Gene Query: P4HA2

Dataset Description Geneva Score
SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 75.8
Gene expression analysis in response to hypoxic pathway inhibition 75.41
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 73.68
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 68.46
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 68.46
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 68.38
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 66.82
Ultracentifugation and nanoscale deterministic lateral displacement (nanoDLD) of samples for exRNA analysis 58.73
Global expression profiles in cardiac progenitor cells generated by ISX-9 55.72
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 55.72
RNA-seq of human iPS derived macrophages with or without KLF1- transcription factor Activation 53.91
High-throughput RNA sequencing on circular RNA profiles of human pancreatic cancer cell lines and gemcitabine resistant pancreatic cancer cell lines. 53.8
Overexpression of PHF8 promotes an EMT-related gene signature in MCF10A cells 53.2
ETS family proteins bind glucocorticoid receptor: relevance for treatment of Ewing sarcoma 51.49
Global gene expression profiles of cardiomyocytes differentiated from human pluripotent stem cells (hiPSC-CMs) in 3D culture exposed to ethanol 50.86
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 48.73
HNF1 regulates critical functions of the human epididymis epithelium. [RNA-Seq] 47.77
HNF1 regulates critical functions of the human epididymis epithelium. 47.77
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 47.18
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 45.96
Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted hearts 44.26
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 43.94
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 43.76
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 41.79
RNA profiling Analysis of the Serum Exosomes Derived from Active and Latent M.tuberculosis infectious Patients 41.77
Profiling in vivo Bone Lesion (IVBL) and Orthotopic tumors by Next Generation Sequencing 41.23
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 40.89
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells with PolyIC treatment 39.59
Gene expression changes in HSV-1 infected HeLa cells with knockdown of B2M 39.39
Safeguarding nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis 39.04
Analysis of Combined Transcriptomes Identifies Gene Modules Differentially Responding to Pathogenic Stimulation in Vascular Smooth Muscle and Endothelial Cells 38.98
Genome-wide expression profiling of an in vitro model for studying esophageal epithelial differentiation 38.86
RNA sequencing of GlyH-101-treated MCF-7 cell line 37.41
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 37.04
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 36.47
Cerebellar differentiation in Ataxia-Telangiectasia 36.37
RNA expression profiles from HUVECs overexpressing adenovirally delivered HIF1a and HIF2a proteins 33.75
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 33.22
Ribo_seq (aka ribosome profiling) analysis of control and Myc-induced U2OS cells 32.92
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 32.61
XBP1s Activation Globally Remodels N-Glycan Structure Distribution Patterns 32.33
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 32.27
Single-cell expression profiling reveals new roles for G-protein-coupled receptors in the regulation of Th17 pathogenicity 31.89
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 31.53
A role for ZNF598 in post-transcriptional gene regulation 31.44
Gene expression profile using RNA-seq in WC00060 or SR-0788 cells transfected with siRNA for KPC1 or control 31.18
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 30.6
Molecular mechanism underlying increased ischemic damage in the ALDH2*2 genetic polymorphism using a human iPSC model system 30.58
Poly(ADP-ribosyl)ation dependent changes in CTCF-chromatin binding and gene expression in breast cells 29.77
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis 29.56
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis [RNA-seq] 29.56
Therapeutic targeting of GCB- and ABC-DLBCLs by rationally designed BCL6 inhibitors 29.52
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 28.62
High level DNA repair gene expression in human ES cells 28.18
Functional role of SLIT2 and ROBO1 in trophoblasts 27.44
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 27.27
Transcriptomic profiling of human coronary artery endothelial cells under laminar shear stress (LS), oscillatory shear stress (OS) and static culture (ST) 27.09
Genes regulated by SPDEF or FOXA3 in A549 lung carcinoma cells [RNA-seq] 26.9
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 26.77
Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells 26.77
Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells 26.24
mRNA expression data from human parthenogenetic haploid ESCs (hPGES), normal ESCs (H9) and human fibroblast 25.86
Genomic analysis of human parthenogenetic haploid ESCs (hPGES), normal human ESCs(H9) and human forskin fibroblast 25.86
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 25.77
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 25.76
High-throughput RNAi cell viability screen to identify selective targets for EWS-FLI1 positive Ewing sarcoma 25.74
Ebola virus (EBOV) infection of ARPE-19 cells 25.69
Transcriptional Signatures of Hypoxic and Inflammatory Renal Epithelial Injury 25.55
An atlas of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2 25.48
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells 25.46
Gene expression profiling of iPSC-derived cardiomyocytes with BAG3 mutations 25.27
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 24.81
A549 cells and MSR-A549 cells 24.81
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 24.36
Genome-wide chromatin analysis of Ewing sarcoma 24.36
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging 24.11
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 24.07
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 24.07
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 23.9
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors 23.85
A histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing 23.8
PAX3-FOXO1 requires BRD4 to drive oncogene addiction in RMS cells [RNA-seq] 23.56
Epigenetic Lanscape and BRD4 Transcriptional Dependency of PAX3-FOXO1 Driven Rhabdomyosarcoma 23.56
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 23.48
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 23.48
Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols 23.36
RNA-seq data from human SGBS adipocytes differentiated with marine oxohexadecenoic acids 23.18
Human iPSC derived glomeruli facilitate accurate modelling of podocytopathy 23.12
Epigenome regulation during epidermal lineage commitment [ATAC-seq, RNA-seq] 23.09
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 22.84
4sU-seq of HFF exposed to salt and heat stress 22.8
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues 22.63
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues (sequencing) 22.63
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of human mesenchymal stem cells differentiation from human embryonic stem cells and adult bone marrow mesenchymal stem cells 22.47
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 22.3
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq and microarray 21.93
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq 21.93
Genome-wide transcriptome profiling of NEDD9-regulated genes using RNA-seq 21.86
Telomere-Dependent and Telomere-Independent Roles of RAP1 in Regulating Human Stem Cell Homeostasis 21.63
Transcriptomic analysis of T84 colon carcinoma cell line treated with trametinib, JQ1 or their combination 21.63
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq] 21.54
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition 21.54
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 21.52
Regulation of hypoxia-inducible factor activity by ZMYND8 21.52
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 21.47
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 [RNA-seq] 21.47
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 21.39
Transcriptome analysis in HT29 and SW480 cells depleted of Prdx2 21.27
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 21.2
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 21.2
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 21.2
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 21.2
Identification of mesothelial-to-mesenchymal gene signature in ascitic fluid-isolated mesothelial cells through RNA-sequencing 21.19
Silencing SPIB in attached and floating state of H1703 lung cancer cells 20.84
Effect of estrogen (E2) treatment on the C4-12 relative to the MCF7 cells 20.68
Gene expression profiling of human MSC-educated macrophages vs. classical macrophages from bone marrow and blood 20.67
Genome-wide RNA-sequencing (RNA-seq) of benign and malignant prostate cell lines without and with androgen (R1881) stimulation. 20.54
Gene expression profile of HGC27 and LMSU gastric cancer cell p53 KO and KD 20.42
RNA-Seq of cKIT+ sorted cells from 16-16.5 week old fetal testes and ovaries and RNA-Seq of TRA-1-60+ H1 hESCs 20.35
Mesothelioma xenografts in nude mice: PBS treated versus pirfenidone treated 20.33
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 20.08
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 20.08
Genome-wide Analysis of Human Constitutive Androstane Receptor (CAR) Transcriptome in Wild-type and CAR-knockout HepaRG cells 20.03
A novel non-canonical signaling pathway mediates TGF-β1-induced glucocorticoid insensitivity in epithelial cells 19.98
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 19.91
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 19.85
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 19.84
STVI-120 Induction of differentiation in human epidermal stem cells followed by differential splicing analysis 19.83
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 19.77
RNA-seq analysis of BAP1-depleted uveal melanoma cells 19.76
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 19.61
Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma 19.53
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected EVT cells 19.48
Single-cell ID-seq identifies BMP signaling as a driver of a late stage epidermal differentiation program. 19.39
Effect of BMP inhibition or stimulation of primary human keratinocytes 19.39
Hypoxic transcriptome of SQ20B human head and neck cancer cells 19.18
Rorc disruption in human FG pancreatic cancer cells 19.06
Endothelial gene expression analysis 19.0
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 19.0
EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling 18.81
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 18.71
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 18.71
The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion 18.59
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG 18.4
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG functional reactivation [human cells RNA-seq] 18.4
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 18.25
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 18.25
Interferon-γ Converts Human Microvascular Pericytes into Negative Regulators of Alloimmunity through Induction of Indoleamine 2,3-Dioxygenase 1 18.16
Gene expression changes after LOC550643 silencing 18.02
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 17.96
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 17.91
Next Generation Sequencing Facilitates Quantitative Analysis of human patient derived primary Glioblastoma (GBM) cancer cell Transcriptomes 17.77
Expression data from human perivascular stem cell-derived extracellular vesicles (PSC-EVs) and PSCs 17.67
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 17.61
The SUMO Pathway as a Therapeutic Option in Pancreatic Cancer 17.57
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 17.51
Identification of gene signature in ascitic fluid-isolated mesothelial cells from high grade serous ovarian cancer patients 17.46
SIX4 acts as a master regulator of genes associated with the malignant phenotype of non-small cell lung cancer cells 17.38
DJ-1 is dispensable for human stem cell homeostasis 17.37
Chemical Enhancement of Direct Cardiac Reprogramming In Vitro and In Vivo 17.03
Generation of induced neural stem cells from urine derived cells by synthetic mRNA 17.03
Multiple waves of transcriptome changes during extended hypoxic induction in human pulmonary microvascular endothelial cells 16.94
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 16.83
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming 16.69
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming (RNA-seq fibroblasts) 16.69
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 16.61
Differential gene expression of human melanoma cells [RNA-seq] 16.61
Rna-seq transcriptome data for insulin-GFP+ cells differentiated from NEUROD1 knock out and NEUROD1+/+ control human embryonic stem cells. 16.61
NEUROD1 dependent gene regulation in murine pancreatic endocrine cells and human stem cell derived insulin producing cells 16.61
Gene expression profile of multiple myeloma cell lines treated with CB-5083 16.6
Effects of Freeze-Thawing and Intravenous Infusion on Mesenchymal Stromal Cell Gene Expression 16.59
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+ T regulatory cells activation 16.41
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of AIM2. 16.33
mRNA expression in iPS cells generated by a synthetic self-replicative RNA 16.13
CSL RNA-Seq on HKC and SCC cell lines 16.11
CSL 16.11
Alu RNA modulates the expression of cell cycle genes in human fibroblasts 16.0
Small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes 15.97
High-throughput RNA sequencing of human preovulatory cumulus and mural granulosa cells (mRNA) 15.97
Single-cell analysis reveals stochastic regulation of type I IFN production by plasmacytoid dendritic cells and identifies host-derived environmental cues as amplifier of type I IFN production 15.83
Simultaneous quantification of antibody-RNA conjugates and the transcriptome from fixed cells by RAID 15.81
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs 15.79
ELF1 expression in prostate cells reduces oncogenic ETS functions and promotes senescence and sensitivity to chemotherapy through distinct gene expression programs [RNA-seq] 15.79
Transcriptional repression in hypoxia is mediated by the Sin3A histone deacetylase complex [RNA-seq] 15.77
Transcriptomic of MKD (MUC1 kidney disease) patient compares to normal derived kidney epithelial cells 15.75
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 15.71
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq] 15.71
Maturation of human iNSCs 15.61
The Unfolded Protein Response Regulator, ATF6, Promotes Mesodermal Differentiation 15.37
Postnatal lipids drive hepatocyte maturation 15.35
Paxillin regulates genomic networks in prostate cancer [LNCaP] 15.35
mRNA differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 15.31
Differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 15.31
Effects of human adipose tissue-derived and umbilical cord tissue-derived mesenchymal stem cells in a dextran sulfate sodium-induced mouse model 15.28
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 15.26
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 15.26
RNA-seq of young and quiescent MRC-5 human fibroblasts 15.24
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 15.18
Changes in chromatin accessibility and gene expression induced by overexpression of ONECUT transcription factors 15.13
Profiling of gene expression using RNA-Seq in fibroblasts, iPSCs, iPSC-derived neurons and cells overexpressing Onecut transcription factors 15.13
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 15.12
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 15.1
Three congruent human Schwann cell models of CMT1A reveal a converged phenotype 14.9
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells (RNA-seq) 14.87
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells 14.87
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 14.84
Human neutrophil genome during PMA- and E. coli encounter-induced activation 14.81
RNA-seq profiling of the human neutrophil genome during PMA- and E. coli encounter-induced activation 14.81
Differentially expressed vascular development genes for iPSC-ECs from CDI 14.79
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 14.71
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition 14.71
Sensitivity and engineered resistance of myeloid leukemia cells to BRD9 inhibition (RNA-seq) 14.71
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family (RNA-seq) 14.59
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family 14.59
Short and long-term effects of CDK4/6 inhibition on early stage breast cancer 14.55
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 14.51
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock 14.5
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock [RNA-Seq] 14.5
Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer 14.46
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq] 14.46
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation 14.46
Radiomic and gEnomic approaches for the enhanced DIagnosis of REnal Cancer (REDIRECt): A translational pilot study 14.45
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 14.44
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 14.26
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 14.26
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 14.21
Modeling and characterization of the dynamic gene regulatory networks underlying cancer drug resistance based on time-course RNA-seq data 14.21
Be1 and Be2 B cells are transcriptionally distinct 14.21
RNA deep sequencing analysis of human brain microvascular endothelial cells (ECs) treated with glioma-conditioned medium (glioma-CM) 14.17
Efficient direct reprogramming of c-Kit− mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression 13.99
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 13.98
Decrease in EZH2 histone methyltransferase mediates the effects of fluid shear stress (FSS) in endothelial cells 13.81
Characterization and therapeautic application of mesenchymal stem cells with neuromesodermal origin from human pluripotent stem cells 13.8
Next Generation Sequencing Facilitates Quantitative Analysis of Human Primary and Pluripotent Stem Cell-Derived Epicardial Cell Transcriptomes 13.75
RNA-sequencing WT vs SOCS3 knockout Glioblastoma stem-cells 13.74
SRSF2 mutations impair hematopoiesis and alter exon recognition 13.7
Dermal fibroblasts play a central role in skin model protection against C. albicans invasion 13.58
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 13.48
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 13.48
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 13.47
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 13.47
RNA sequencing reveals transcriptional changes after Hippo signaling activation in podocytes 13.43
Replicated transcriptome profiling of Normal and Cancerous Prostate Cells [RNA-Seq] 13.43
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer [RNA-seq] 13.39
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer 13.39
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 13.32
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression 13.27
Transcriptomic profile of human embryonic renal corpuscles 13.24
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 13.22
Charaterization of genetic alterations and gene expression signatures found in BCR-ABL inhibitor-resistant KCL-22 subpopulations and single clones 13.2
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer (RNA-Seq) 13.19
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer 13.19
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 13.17
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 13.17
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells 13.12
Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells 13.12
Effect of MDK expressing Melanoma cells conditioned media in Human LEC 13.11
RNA-seq identifies novel lncRNAs involved in vascular smooth muscle cell proliferation 13.05
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 13.04
Genome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA 13.0
High-efficiency RNA-based reprogramming of human primary fibroblasts 12.92
The Genomic Landscape of Atypical Fibroxanthoma 12.89
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations [RNA-seq] 12.83
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations 12.83
Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML 12.79
Apoptotic endothelial cells release small extracellular vesicles loaded with immunostimulatory viral-like RNAs 12.77
Peroxisome Proliferator-activated Receptor gamma- Deficiency in Endothelial Cells Impairs Angiogenic Capacity by Loss-of E2F1 Mediated Wnt Effector Genes 12.69
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 12.67
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 12.67
Cell-specific expression and function patterns of microRNA-150-5p in liver fibrogenesis 12.63
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 12.62
Neurofibroma 12.61
Differential expression in wild-type and mutant neurofibroma and MPNST cell lines 12.61
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 12.57
SUV420H2 knockdown in PANC-1 12.56
The effect of Foxc1 deficiency on undifferentiated and differentiated human primary keratinocytes 12.54
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 12.44
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 12.44
Evidence for HOXC6 as a potential molecular marker for non-small cell lung cancer 12.26
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 12.25
Gene expression analysis of immortalized human liver progenitor-like cells in culture 12.14
Regionally distinct astrocyte interferon signaling promotes blood-brain barrier integrity and limits immunopathology during neurotropic viral infection 11.91
Enhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest 11.9
Global analyses of the effect of different cellular contexts on microRNA targeting (RNA-Seq) 11.87
Global analyses of the effect of different cellular contexts on microRNA targeting 11.87
Transcriptomic profiling of mesenchymal stem cells (MSC) differentiation into mesangial cells 11.86
RNA-sequencing experiment: Treatment of MCF-7 breast cancer cells with the novel small molecule ZNA 11.78
Morphological and molecular characterization of human dermal lymphatic collectors 11.78
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 11.76
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells 11.75
Mycobacterium bovis Bacillus Calmette-Guerin (BCG) reprograms melanoma microenvironment to promote antitumor T cell responses 11.65
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors 11.64
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors [RNA-seq] 11.64
Transcriptomics profiling of Alzheimer’s disease reveal novel molecular targets 11.64
Transcriptome profiling of Normal and Cancerous Prostate Cells 11.62
Knockdown of FOXP1 promotes the development of lung adenocarcinoma 11.56
Novel kinase fusion oncogenes in post-Chernobyl radiation-induced pediatric thyroid cancers 11.54
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 11.44
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells 11.38
MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma 11.27
Determining effects of microbial metabolite, Urolithin A on colon epithelial cells 11.08
Differential gene expression by suppression of either SOX2 or TP63 in KYSE70 human esophageal squamous carcinoma cell line. 11.05
Isolation and Functional Interrogation of Adult Human Prostate Epithelial Stem Cells at Single Cell Resolution 11.05
ChIP-seq of ER and RUNX2 in MCF7 breast cancer cell lines 11.05
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 10.95
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 10.92
Transcriptome analysis in Neobractatin treated cells 10.91
RNA-seq of cells with TET1 knockout 10.84
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 10.79
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 10.79
Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors 10.76
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and SMAD4 Y95 Mutation Transcriptomes 10.74
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 10.71
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 10.63
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 10.61
A prostate cancer chromatin interaction map 10.61
Subcellular RNA fractions of HSV-1 infected primary human fibroblasts 10.6
Clinker: visualizing fusion genes detected in RNA-seq data 10.57
GATA3 enhances the neurogenic potential of primary human astrocytes after traumatic injury [exp1] 10.57
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 10.55
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 10.51
Identification of downstream genes regulated by YAP1 through knockdown and overexpression of YAP1 in U251 cell with a stably expression of mutant APP 10.47
Global loss of epigenetic and transcriptional fidility defines a subclass of cancer with immunotherapy resistance 10.44
Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer. 10.43
Metastasis in triple-negative breast cancer 10.43
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 10.4
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 10.4
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 10.4
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 10.29
RNA sequencing of human mammary epithelial cells 10.25
Transcriptomic analysis of the effect of trastuzumab in human iPSC-CMs 10.12
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [RNA-Seq III] 10.11
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 10.06
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 10.06
Reduced CYFIP1 in human neural progenitors as 15q11.2 deletion model: donor specific dysregulation of schizophrenia/epilepsy genes 10.05
Zika Virus Has Oncolytic Activity against Glioblastoma Stem Cells 9.95
The interplay between SOX4 and SMAD3 in the context of breast cancer 9.92
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 9.88
RNA-seq of MDA-MB-231 cells with TET1 knockout 9.83
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming 9.78
RNA-seq and Microarray in Transcriptome Profiling of Anterior Cruciate Ligament Tears: Implications for Prognostic Biomarkers Discovery 9.7
Enriched retinal ganglion cells derived from human embryonic stem cells (RNA-seq) 9.66
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 9.61
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 9.61
Transcriptome of melanoma cell lines resistant to inhibition of the MAPK pathway. 9.57
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 9.47
Small molecule targets TMED9, promotes lysosomal degradation to reverse proteinopathy 9.32
Transcriptomics analysis of enteroendocrine cells following vertical sleeve gastrectomy 9.2
Transcriptomics analysis of human jejunal enteroendocrine cells after vertical sleeve gastrectomy 9.2
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance 9.15
Combined Genome and Transcriptome Sequencing to Identify Allelic Selection in Epithelial Ovarian Cancer 9.15
RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues 9.1
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 9.06
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis [bulk RNA-Seq] 8.99
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis 8.99
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 8.69
RNA-Sequencing of human dermal lymphatic endothelial cells (HDLEC) treated with siRNA targeting YAP/TAZ and YAP5SA 8.64
Gene expression profile in endometrial organoids cultured in normal follicular phase vs PCOS-like hormone profile 8.57
Transcriptome analysis of RANK-positive and RANK-negative luminal progenitor subpopulations in the human breast 8.54
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling (mRNA) 8.49
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling 8.49
Transcriptome-wide analysis to determine miR-200a targets in melanoma cell lines 8.48
Histone demethylase LSD1 is required for germinal center formation and BCL6 driven lymphomagenesis 8.46
Transcriptional changes in lymphoma cells induced by LSD1 depletion 8.46
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 8.43
Wide-spread disruption of transcription termination in HSV-1 infection: Next-generation sequencing of translational activityd by ribosome profiling 8.4
U2AF1 mutations alter splice site recognition in hematological malignancies 8.31
Glioma Stem Cell Specific Super Enhancer Drives Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling 8.27
FOXO1 is required for binding of PR on IRF4, novel transcriptional regulator of endometrial stromal decidualization 8.1
Progesterone receptor transcriptome and cistrome in decidualized human endometrial stromal cells 8.1
Progesterone Receptor- and FOXO1-dependent transcriptomes decidualized human endometrial stromal cells 8.1
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 8.06
LIN28A modulates splicing and gene expression programs in breast cancer cells [RNA-Seq] 8.05
LIN28A modulates splicing and gene expression programs in breast cancer cells 8.05
Dnmt3a and Dnmt3b associate with enhancers to regulate human epidermal stem cell homeostasis 8.04
RNA-seq analysis of A2780 and OVCAR3 human ovarian cancer cell lines after overexpression of collagen type XI alpha 1 (COL11A1) 8.03
Transcriptome analysis of ECFCs treated with GSK-343 and Panobinostat 8.01
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 7.97
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 7.77
Transcriptome profiling of microRNA-mediated neuronal reprogramming with REST repression at day 7 7.58
Gene Expression Profiling of WT and KDM3A Knocked out Cell 7.46
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 7.46
Gene expression changes due to PARP knockdown in human cells 7.3
A comparison of gene expression between lesional and non-lesional derived keratinocytes of Hailey-Hailey disease patients. 7.29
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 7.28
Transcriptome of human ILC2s; primary vs IL-1b-primed 7.21
Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming 7.16
Zika virus infection reprograms global transcription of host cells to allow sustained infection 7.1
Ribosome profiling of TGFb-treated cells indicates reduced leucine availability 7.1
Whole transcriptome splicing analysis in isogenic lung epithelial and adenocarcinoma cell lines with or without a recurrent splicing factor mutation, U2AF1 (S34F) 7.01
Integrative analysis of mRNA and lncRNA profiles identified pathogenetic lncRNAs in esophageal squamous cell carcinoma 7.0
transcriptome studies of BRD4 inhibitor BDF-1253 on renal clear carcinoma 786-O cells 6.87
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 6.83
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 6.83
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 6.77
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells 6.72
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 6.62
Genome-wide occupancy of FLAG-MED25 and ETV4 and expression profiling of shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 6.61
shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 reveals set of genes potentially coregulated by MED25 and ETV4 6.61
Comparing effects of perfusion and hydrostatic pressure on human chondrocytes using gene profiles 6.5
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 6.43
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export II 6.41
Derivation and differentiation of haploid human embryonic stem cells [RNA-Seq 1] 6.35
The NFkB subunit RELA is a master transcriptional regulator of the committed epithelial-mesenchymal transition in airway epithelial cells 6.27
RNA seq with AML (NB4) cells upon FTO inhibition 6.14
A Novel Population of Human Cardiac Resident Mesenchymal Stem Cells 6.13
Aneuploidy-induced cellular stresses limit autophagic degradation. 6.02
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 6.02
Restoration of Progranulin Expression Rescues Cortical Neuron Generation in Induced Pluripotent Stem Cell Model of Frontotemporal Dementia 5.96
In situ CAPTURE of chromatin interactions by biotinylated dCas9 5.86
RNA-seq transcriptonal profiling in human K562 cells with or without dCas9 and sgRNAs 5.86
Human Induced Pluripotent Stem Cells Recapitulate Breast Cancer Patients’ Predilection to Doxorubicin-Induced Cardiotoxicity 5.81
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 5.8
Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells 5.8
RNA-Seq of Breast and Ovarian Cancer Cell Lines 5.77
PANCR, the PITX2 adjacent noncoding RNA, is specifically expressed in human left atria and regulates PITX2c expression 5.74
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 & MCM7 5.71
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 5.69
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 5.67
IKZF1 as a Master Regulator of Immune Infiltrate Recruitment in Solid Tumors 5.65
iPSC derived motor neuron cultures from C9ORF72 carriers 5.6
Early transcriptome profiling of microRNA-mediated neuronal reprogramming [RNA-seq timecourse] 5.5
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 5.4
Differentially expressed genes during pancreatic bud differentiation in cellular aggregates 5.37
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 5.26
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 5.26
The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis 5.09
mRNA sequencing analysis of cultured human primary airway epithelial cells upon exposure to PMN exosomes 5.05
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth [RNA-Seq] 5.02
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth 5.02
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 5.02
Integrated Systems Biology Analysis of KSHV Latent Infection Reveals Viral Induction and Reliance on Peroxisome Mediated Lipid Metabolism 4.93
4.92
Sex differences in transcriptomic profiles in aged kidney cells of renin lineage 4.9
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 4.87
Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis 4.84
Characterisation of the EZH2 regulated transcriptome in de novo transformed cells (RNA-Seq) 4.83
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs 4.66
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition 4.59
MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block 4.59
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 4.55
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 4.55
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 4.55
cKIT+ sorted cells from 57-137 day old fetal testes and ovaries 4.41
RNA-Seq of cKIT+ sorted cells from 53-137 day old fetal testes and ovaries and RNA-Seq of TRA-1-81+ H1 and UCLA1 hESCs. 4.41
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 4.2
The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis 4.18
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 4.04
Global response to chemotherapy-induced apoptosis 4.03
RNA-Seq from human ILC transitional populations 4.01
Expression profiling of ILC transitional populations and Aiolos accessability and H3K27ac histone modifications in transfected MNK3 cells 4.01
Gene expression profile of melanoma cell lines after overexpression or knockdown of KPC1 3.83
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 3.79
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 3.79
Bone marrow derived human B cells [normal proB] 3.72
RNA-Seq analysis of prostate cancer cell line LNCaP treated with vehicle, androgen, androgen and IMTPPE, androgen and JJ-(+)-450, androgen and JJ-(-)450, androgen and enzalutamide 3.6
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 3.56
Specific labeling of stem cell activity in human colorectal organoids using an ASCL2-responsive minigene 3.53
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 3.33
Study of dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest 3.32
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ super-enhancers 3.28
RNA-Seq identifies condition-specific biological signatures of ischemia-reperfusion injury in the human kidney 3.23
A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells 3.22
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 3.18
RNA sequencing of prostate cancer and normal tissue from African Americans and European Americans 3.17
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 3.05
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 2.98
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 2.97
T47D xenografts treated with various combinations of ER- and PR-targeting therapies 2.81
Illumina Human Polycystic Liver Disease and Normal Biliary Stem Cell RNAseq 2.81
Effect of ILF3 depletion in HeLa cells on RNA steady state levels 2.8
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 2.74
The transcriptome of Kawasaki Disease arteritis 2.62
CRISPR/Cas9 Screens Reveal Epstein-Barr virus Synthetic Lethal Targets 2.49
Gene expression profile of regenerated CD8αα T cells and CD8αβ T cells from LMP2 T-iPSCs 2.18
Sequencing of ponatinib-resistant LC-2/ad derivatives (PR1 and PR2) and parental LC-2/ad cells 2.16
Loss of endometrial plasticity in recurrent pregnancy loss 2.14
Expansion of adult human pancreatic tissue yields organoids harbouring progenitor cells with endocrine differentiation potential 2.13
Similarity of therapeutic networks induced by a multi-component herbal remedy in neurovascular unit cells 2.11
Metabolism as an early predictor of DPSCs aging 2.07
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (human cell lines RNA-Seq) 1.92
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 1.92
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 1.69
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells (Poly(I:C) and LPS) 1.55
Comparison of small cell lung cancer PDX model FHSC04 for response to LSD1 inhibitor RG6016/ORY1001 1.34
Transcriptome-analysis of patient-derived normal and ulcerative colitis intestinal epithelial organoids 1.28
Hypoxic regulation of gene expression in HUVEC is dominated by EPAS1 1.26
Transcriptional analysis of ZIKV-infected Ifnar-/- and Ifnar+/- placentas and IFN-beta (IFN-b) or IFN-lambda (IFN-l) treated human mid-gestation chorionic villus explants 1.22
Analysis of transcriptional differences after IFN-beta (IFN-b) or IFN-lambda (IFN-l) treated human mid-gestation chorionic villus explants 1.22
RNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation 1.15
Mutant p63 disrupts the key specification switch from the multipotent cell state to stratified epithelia during epithelial differentiation/in ectodermal dysplasia disorders 0.87
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 0.79
RNA-seq of cancer cell lines treated with T-025 0.79
Immune Checkpoint Regulation of Pulmonary Fibrosis [bulk RNA-seq] 0.77
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. 0.6
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.49
Whole transcriptome sequencing of the human thyroid primary cells with knock-down of the NRG1 gene 0.27
RNA-Seq profiling of iPSC-derived ventricular and atrial cardiomyocytes 0.26
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.2
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 0.18


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