Gene Query: PARP2

Dataset Description Geneva Score
Gene expression by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1.4 knock-down and multiple H1 variants 94.82
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 40.7
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 29.27
A common cell state in Triple Negative Breast Cancers represents a druggable vulnerability 25.02
Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma engages the ER-stress response II 23.58
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 21.62
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 19.09
Proteotranscriptomic profiling of potential E6AP targets in prostate cancer cells 17.93
Hijacking of stress response machinery by oncogenes in acute leukaemia 16.37
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 16.37
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 16.29
Mapping interactions for the TNIP2 hub protein 15.58
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 14.82
Tracking of dCas9-methyltransferase footprints 14.72
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 13.67
Transcriptome analysis of BAP1 knockout and restoration 13.67
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 13.31
RNA-seq analysis to identify the genes regulated by p53-SET interplay 13.25
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 13.16
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 12.95
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 12.47
LNCaP treated with iBET 12.14
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 12.06
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 11.98
N6-methyladenine DNA Modification in Glioblastoma 11.98
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 11.7
Quantitative Analysis of negative control and overexpression-TRIB1 in PC3 and DU145 Transcriptomes 11.53
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 11.44
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 11.37
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 10.95
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 10.92
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 10.92
Quantitative comparison between cellular mRNAs and exosomal mRNAs in human iPSC-derived motor neurons 10.49
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 10.25
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 10.25
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 10.22
microRNA suppresses prostate cancer stem cells and metastasis by inhibiting a cohort of pro-metastasis targets including CD44, Rho GTPases and EZH2 10.19
The flightless I protein is involved in the genome-wide mRNA post-transcriptional regulation in lung carcinoma cells 10.14
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 10.1
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 9.89
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas 9.82
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 9.67
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 9.54
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 9.54
BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors 9.49
MDM2 and MDM4 are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors 9.39
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 9.35
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 9.17
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 9.12
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 9.02
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 9.02
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 8.9
RNA-seq analysis of control and NRDE2-depleted breast cancer cells 8.67
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 8.45
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 8.4
3’ Uridylation Expands miRNA Target Repertoire 8.28
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 8.11
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 8.0
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 7.91
Disruption of the exocyst induces podocyte loss and dysfunction 7.82
A549 cells and MSR-A549 cells 7.81
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 7.81
Transcriptional responses of human insulinoma cells to acute cytokine exposure 7.78
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 7.76
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 7.73
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 7.7
A single-cell atlas of the human cortex reveals drivers of transcriptional changes in Alzheimer’s disease in specific cell subpopulations 7.63
Effect of BRCA1 overexpression on genetic expressions of cervical cancer based on next generation sequencing 7.53
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 7.39
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 7.37
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 7.26
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 7.15
A role for ZNF598 in post-transcriptional gene regulation 7.06
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 7.05
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 7.05
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 7.05
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 7.03
RNA-Seq of cKIT+ sorted cells from 16-16.5 week old fetal testes and ovaries and RNA-Seq of TRA-1-60+ H1 hESCs 7.02
The BCL6 RD2 domain governs commitment of activated B-cells to form germinal centers 6.99
RNA-seq analysis of HT-29, MCF10A, and MDA-MB-436 cells 6.99
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 6.91
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 6.91
RNAseq of HEK293 cells after Chtop knockdown 6.77
Co-transcriptional loading of RNA export factors shapes the human transcriptome 6.77
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 6.76
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 6.76
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 6.75
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer 6.74
ZNF804A transcriptome networks in differentiating human neurons derived from induced pluripotent stem cells 6.73
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 6.64
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 6.61
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 6.61
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 6.52
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 6.5
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 6.43
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 6.42
A transcriptome dataset revealing the molecular features of breast cancer stem cells 6.39
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 6.35
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 6.35
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 6.34
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1 6.34
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 6.34
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 6.34
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells 6.33
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 6.3
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 6.3
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA) 6.3
Seletive inhibition of CDK9 in DLBCL cell lines 6.27
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 6.22
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 6.2
Differential responses by human respiratory epithelial cell lines to respiratory syncytial virus reflect distinct patterns of infection control 6.2
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 6.17
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 6.15
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 6.15
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 6.11
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 6.05
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 6.05
RNA sequence analysis of stable versus reversible EMT events and the resultant metastases 6.0
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 5.99
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 5.88
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 5.8
Functional role of SLIT2 and ROBO1 in trophoblasts 5.78
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 5.67
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 5.67
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 5.63
The landscape of alternative splicing in aggressive prostate cancers 5.63
Alu RNA modulates the expression of cell cycle genes in human fibroblasts 5.62
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 5.56
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 5.5
Genetic disruption of COX-1 inhibits multiple oncogenic pathways 5.46
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 5.46
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 5.45
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 5.45
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells 5.42
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 5.37
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 5.34
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 5.33
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 5.31
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 5.3
Chromatin-informed inference of transcriptional programs in gynecologic cancers 5.28
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 5.28
LncRNA-GAS5 negative regulation of YAP-target genes expression 5.28
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 5.27
Expression changes in melanoma cell lines pre MAPKi treatment vs. post-MAPKi resistance (RNA-seq_CellLine.batch2) 5.17
Transcriptomic Profiling of Developing Human Paraxial Mesoderm from 4.5-5 Weeks of Gestation Human Embryos 5.17
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 5.13
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 5.1
AUF-1 affected genes in human skin cells 5.09
Enriched EWSR1 and EWS-FLI1 RNA-seq of HNRNPH1-silenced TC32 Ewing sarcoma and 293T human embryonic kidney cells. 5.06
Gene target specificity of the Super Elongation Complex (SEC) family: How HIV-1 Tat employs selected SEC members to activate viral transcription 5.06
FBXW7 modulates stress response by post-translational modification of HSF1 5.02
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 5.02
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 5.01
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 5.0
Global Mapping of Human RNA-RNA Interactions 4.98
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 4.97
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 4.97
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer 4.92
Transcriptional profiling of LS1034 cells treated with tepoxalin 4.91
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 4.9
Biological effect of chronic mistranslation in mammalian cells 4.87
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 4.85
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 4.84
Gene expression analysis of immortalized human liver progenitor-like cells in culture 4.83
Bi-allelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney 4.8
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 4.8
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 4.79
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 4.79
Single-cell analysis of adult human ovary using 10X genomics 4.78
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 4.74
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 4.73
IL-33 activates tumor stroma to promote intestinal polyposis 4.72
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 4.72
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 4.69
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 4.69
Characterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer 4.68
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways 4.67
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress 4.63
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 4.61
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 4.61
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 4.61
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression 4.58
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 4.57
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 4.57
Chronophin regulates metabolic and transcriptomic features of glioblastoma stem-like cells 4.54
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 4.53
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 4.51
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 4.51
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 4.44
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 4.43
Discovery of cis-spliced chimeric RNAs between adjacent genes in human prostate cells 4.43
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 4.4
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 4.4
Transcriptomes analysis for the regulation of Z36 induced autophagy in HeLa cell death 4.37
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 4.35
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 4.33
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 4.28
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 4.28
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 4.27
Gene expression in GBM with Cav3.2 inhibition 4.25
DART-seq: an antibody-free method for global m6A detection 4.24
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 4.22
Essential Roles of SETD7 as Transcriptional Activator and Co-regulator of H3K36me in Cardiac Lineage Commitment 4.21
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 4.2
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 4.2
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 4.18
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 4.18
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 4.18
Charaterization of genetic alterations and gene expression signatures found in BCR-ABL inhibitor-resistant KCL-22 subpopulations and single clones 4.16
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 4.16
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 4.15
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 4.15
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export II 4.15
High-efficiency RNA-based reprogramming of human primary fibroblasts 4.11
RNA-seq analysis of differentiating human erythroblasts 4.06
Transcriptome analysis of immature and matured human oocytes from patients of young and advanced maternal age 4.05
Sequencing Universal Human Reference RNA by Smart-seq and early barcoding library preparation methods 4.04
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 4.04
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 4.04
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 4.04
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 4.03
A TGFbeta-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression 4.03
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 4.02
A Unique Epigenomic Landscape Defines Human Erythropoiesis 4.02
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 4.02
Transcriptional profile of human STAT1-/- fibroblasts expressing LY6E or empty control vector 4.02
Differential gene expression analysis between proliferating and quiescent human dermal fibroblasts 3.99
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 3.97
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 3.97
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 3.96
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 3.93
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 3.9
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 3.9
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 3.86
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 3.86
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 3.86
Accurate annotation of human protein-coding small open reading frames 3.84
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 3.82
NHLRC1 re-expression in cancer cells 3.82
miR941 overexpression experiment 3.81
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 3.81
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 3.8
Effect of drugs on transcriptomic profiles 3.8
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 3.8
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 3.8
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 3.76
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 3.73
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 3.73
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 3.73
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_RNA-seq] 3.73
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 3.69
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 3.67
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer 3.64
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer (RNA-seq) 3.64
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 3.62
Whole-transcriptome profilings between a pair of HCA7-derived KRAS-wildtype cetuximab sensitive and resistant colon cancer cells from 3D culture 3.62
Effect of CHKA knockdown on C4-2 cell transcriptome 3.61
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 3.6
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 3.59
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 3.59
An optimization system for isolating and sequencing of single human colon cancer cells 3.58
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 3.57
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 3.56
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 3.56
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5’ and 3’ Ends of Genes 3.53
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 3.53
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 3.5
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 3.46
RNA-seq analysis of the role of HBO1 (KAT7/MYST2) in the ovarian cancer cell line UWB1.289. 3.42
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 3.42
Discovering the anti-cancer potential of non-oncology drugs by systematic PRISM profiling 3.4
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 3.4
Transcriptome-wide response to synthetic chromatin protein PcTF 3.4
Molecular Criteria for Defining the Naive Human Pluripotent State 3.39
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 3.38
ETV7 and interferon response 3.38
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 3.36
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 3.35
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 3.35
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 3.35
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 3.33
SLIGRL-induced gene expression changes in NHEK cells 3.3
Silencing p300 in MCF7 cells to study expression and alternative splicing 3.28
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression [RNA-Seq] 3.25
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression 3.25
DAOY-Notch1/Notch2 knockout: transcriptome comparison 3.23
Profiling of escape kinetics of viruses subjected to RNAi 3.22
RNA-sequencing time course of Human Intestinal Epithelial Cells (HIECs) following knockdown of miR-30bcd using complementary locked nucleic acids 3.2
RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 3.2
RNA-seq Profiles in RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 3.2
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 3.19
UV_24h_GRO-Seq 3.18
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 3.16
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 3.16
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 3.16
KLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the bone 3.15
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 3.01
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 3.0
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 2.98
Downregulation of DDX5/DDX17 and REST 2.95
ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression 2.93
single cell RNA-seq from GM12878 (ENCSR673UIY) 2.91
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 2.88
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 2.88
CD73 knockdown effect in pancreatic cancer cell lines 2.88
Controlling for gene expression changes in transcription factor protein networks. 2.88
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer 2.84
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 2.82
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 2.82
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 2.81
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions 2.8
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (ChIP-seq & RNA-seq datasets) 2.77
Depicting early human development and germ cell origin with porcine embryos 2.76
Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation 2.76
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer [RNA-Seq] 2.76
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 2.76
Identification of a LIF-responsive replication-competent human β cell 2.74
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 2.73
Cell cycle dynamics of human pluripotent stem cells primed for differentiation 2.72
Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth 2.71
Gene expression signatures of innate lymphoid cells from human blood 2.69
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 2.67
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 2.67
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 2.65
Functional role of CPPED1 in trophoblasts. 2.63
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 2.62
Gene Expression Profiling of WT and KDM3A Knocked out Cell 2.62
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 2.62
METTL3 and WTAP 2.61
A combinatorial screen of the CLOUD uncovers a synergy targeting the androgen receptor 2.59
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 2.58
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 2.58
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 2.52
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer 2.46
Whole Transcriptomic Sequencing of Metastatic Castration Resistant Prostate Cancer Samples 2.43
Effect of OVO-like 1 knockdown on global transcript expression in differentiated BeWo trophoblast cells 2.42
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 2.42
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 2.42
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes 2.4
Neurofibromin is an Estrogen Receptor alpha Transcriptional Co-repressor in Breast cancer 2.39
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 2.37
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 2.37
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 2.36
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 2.36
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 2.32
A bioinformatics approach reveals novel mechanisms of the OVOL transcription factors in the regulation of epithelial-mesenchymal cell programming and cancer progression. 2.32
Human MAIT cells exit peripheral tissues and re-circulate via lymph in steady state conditions 2.31
Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia 2.23
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 2.22
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 2.22
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 2.11
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 2.09
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 2.09
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 2.08
m6A-dependent regulation of messenger RNA stability 2.08
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 2.07
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 2.07
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 2.03
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 1.97
p53 activity results in DNA replication fork processivity 1.96
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion 1.95
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 1.94
SETBP1-WT and SETBP1-G870S epigenetic landscapes 1.94
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 1.93
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 1.92
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain [RNA-Seq] 1.85
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain 1.85
YAP and MRTF-A, transcriptional co-activators of RhoA- mediated gene expression, are critical for glioblastoma tumorigenicity 1.83
Identification of global XBP1s target gene expression in human prostate cancer cells 1.81
Club cells surviving influenza A virus infection induce temporary non-specific anti-viral immunity 1.81
Comparison of single-cell transcriptomics quality between unfixed cells and cells that were fixed and mock stained according to the RAID procedure 1.78
Functional significance of the HIV-1 Tat signature amino acid residues 1.74
Modulation of nonsense-mediated decay by rapamycin 1.7
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 1.69
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 1.65
Iron response of HepG2 cells 1.65
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 1.64
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 1.63
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner 1.62
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 1.56
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 1.56
RNA-seq analysis upon ARID1B overexpression 1.53
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 1.52
A20 regulates canonical wnt-signaling through an interaction with RIPK4 1.47
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 1.47
SILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors 1.44
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 1.41
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 1.37
Transcriptomics profiling of Alzheimer’s disease reveal novel molecular targets 1.36
The transcriptome and chromatin accessbility landscape of mammalian germline 1.36
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 1.31
Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures 1.3
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 1.28
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 1.26
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 1.24
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 1.24
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 1.23
The DPYSL2 gene connects mTOR and schizophrenia 1.18
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery (RNA-seq data set) 1.16
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery 1.16
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 1.15
Induction of Cardiomyocyte Proliferation [pz-822_human] 1.15
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 1.14
Critical role for Lymphocytes in Producing FLT3LG in Tumors and Driving Checkpoint Therapy-Receptive Immune Microenvironments 1.13
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 1.13
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 1.12
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 1.11
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 1.11
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7 1.09
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 1.08
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  1.08
CDK12 mediated transcriptional regulation in U2OS cells 1.07
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 1.05
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 1.04
Sirt6 Oncogene Mediates PI3K/Akt Signaling Activation in Diffuse Large B-Cell Lymphoma 1.03
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 1.0
Isolation and Functional Interrogation of Adult Human Prostate Epithelial Stem Cells at Single Cell Resolution 0.98
5hmC and gene expression data in breast cancer cell lines treated with an antioxidant 0.93
The cohesin complex prevents Myc-induced replication stress 0.92
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma [RNA-seq] 0.89
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma 0.89
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 0.88
Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models 0.86
Comparative Analysis of Cas9 Activators Across Multiple Species 0.85
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 0.84
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 0.79
RNASeq of Healthy Human Skin Tregs and CD4 Teffs versus Psoriatic Human Skin Tregs and CD4 Teffs 0.78
Genome-Wide Specificity of DNA-Binding, Gene Regulation, and Chromatin Remodeling by TALE- and CRISPR/Cas9-Based Transcription Factors 0.76
Single-cell transcriptomics of human oocytes: environment-driven metabolic competition and compensatory mechanisms during oocyte maturation 0.75
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.74
Transcriptome-wide identification of CELF2 functional targets in T cells 0.74
The impact of oil spill to lung health – insights from an RNA-seq study of human airway epithelial cells 0.74
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 0.73
Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. 0.73
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 0.72
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 0.7
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 0.7
SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate 0.67
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.67
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 0.67
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 0.67
RNA-Seq of cKIT+ sorted cells from 53-137 day old fetal testes and ovaries and RNA-Seq of TRA-1-81+ H1 and UCLA1 hESCs. 0.65
cKIT+ sorted cells from 57-137 day old fetal testes and ovaries 0.65
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] 0.63
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 0.63
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 0.62
The role of CFTR in islet function 0.62
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis [RNA-Seq] 0.61
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis 0.61
Gene expression analysis upon mtDNA depletion [RNA-seq] 0.59
Gene expression analysis upon mtDNA depletion 0.59
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 0.58
RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs 0.58
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  0.54
Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability? 0.53
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 0.53
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.52
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.52
Chemical Enhancement of Direct Cardiac Reprogramming In Vitro and In Vivo 0.5
Gene expression changes due to PARP knockdown in human cells 0.5
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 0.46
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 0.46
Gene expression analysis of human hepatocellular cancers 0.45
Anaylsis of the effect of down-regulation of the EWS-FLI1 fusion protein in Ewing Sarcoma cells by RNA-seq. 0.43
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 0.38
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 0.36
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 0.34
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 0.34
FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA 0.33
Gene expression profile in FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA using RNA-seq. 0.33
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 0.31
Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation 0.31
Exogenous rescue of KLHL9 in SF210 cell line 0.29
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 0.29
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.28
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 0.26
Transcriptional response of human endocervical epithelial A2EN cells to infection with wild-type or CpoS-deficient Chlamydia trachomatis L2/434/Bu 0.26
Transcriptome-wide modulation of splicing by the exon junction complex 0.25
Characterizing the Chemoresistant Ovarian Cancer Population using the Heterogeneous PDX 0.25
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 0.24
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 0.24
RNA-seq analysis reveals endogenous aryl hydrocarbon receptor regulation is highly associated with eicosanoid synthesis and tumor necrosis factor activity in MCF-7 cancer cells 0.2
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line 0.2
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line [RNA-Seq] 0.2
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 0.19
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock [RNA-Seq] 0.17
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock 0.17
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 0.14
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 0.14
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 0.13
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing 0.12
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing (RNA-seq) 0.12
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 0.11
mRNA sequencing of oropharyngeal cancer cell lines 0.11
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 0.11
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 0.1
Function and hormonal regulation of GATA3 in human first trimester placentation 0.06
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 0.05
iPSC derived motor neuron cultures from C9ORF72 carriers 0.02
Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer 0.01


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