Gene Query: PITX2

Dataset Description Geneva Score
High-depth RNA sequencing of isogenic wild-type, PIK3CA-WT/H1047R and PIK3CA-H1047R/H1047R human iPSCs 57.9
Effects of human adipose tissue-derived and umbilical cord tissue-derived mesenchymal stem cells in a dextran sulfate sodium-induced mouse model 52.54
Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells 43.32
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 40.63
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 38.14
RNA sequencing reveals transcriptional changes after Hippo signaling activation in podocytes 36.2
Cerebellar differentiation in Ataxia-Telangiectasia 35.23
Next Generation Sequencing Facilitates Quantitative Analysis of Retinoblastoma Transcriptomes 34.33
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells with PolyIC treatment 34.02
Differentially expressed genes during pancreatic bud differentiation in cellular aggregates 29.94
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells 29.69
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [ChIP-Seq & RNA-Seq] 29.69
Mechanistic Model-Guided Study of Embryonic Morphogenesis 28.02
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq2] 26.33
Transcriptomic and gene ontology profiling of the human corneal cell types 26.1
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma 25.32
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma [RNA-seq] 25.32
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 24.36
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes 23.44
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [RNA-seq] 22.54
Rescue of Fragile X syndrome by DNA methylation editing of the FMR1 22.54
Next Generation Sequencing Facilitates Quantitative Analysis of mesoderm posterior bHLH transcription factor 1(MESP1)+ and MESP1- cells' Transcriptomes 21.77
RNA sequencing of hPSC-derived cardiac progenitors and endocardium 21.3
Endothelial Cells Control Pancreatic Cell Fate at Defined Stages through EGFL7 Signaling 20.43
EP400 is required for Max and MCPyV mediated gene activation 19.73
Transcriptome profiling of self-renewing hESCs and multipotent mesoderm progenitor cells as a function of substrate stiffness 18.29
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 18.23
Histone Demethylases KDM3A and KDM4C regulate mesenchymal stromal cell senescence and bone aging through condensin-mediated heterochromatin organization 17.13
PANCR, the PITX2 adjacent noncoding RNA, is specifically expressed in human left atria and regulates PITX2c expression 17.11
Gene expressions of H9s in different culture systems 17.03
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes 16.91
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes [RNA-seq] 16.91
Postnatal lipids drive hepatocyte maturation 16.23
Differentially Expressed Genes for Atrial Fibrillation Identified using RNA Sequencing from Paired Human Left and Right Atrial Appendages. 15.62
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 15.52
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 15.24
Deep sequencing of transcript levels in pluripotent stem cells and their differentiated derivatives in all three germ layers 15.04
RNA-Seq Analysis in purified iPS cell-derived neuronal samples 14.87
Restoration of Progranulin Expression Rescues Cortical Neuron Generation in Induced Pluripotent Stem Cell Model of Frontotemporal Dementia 14.68
Next Generation Sequencing Facilitates Quantitative Analysis of Human Primary and Pluripotent Stem Cell-Derived Epicardial Cell Transcriptomes 14.64
High-Throughput Kinetic Analysis of Fractional Killing 13.89
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development [set 1] 13.78
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 13.72
Comparative analysis of mesenchymal stem cells derived from amniotic membrane, umbilical cord and chorionic plate under serum-free condition 13.48
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier [human] 13.2
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier 13.2
Heterozygous and homozygous knock-in of PIK3CA-H1047R into human iPSCs 12.99
Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells 12.85
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 12.31
yylncT acts as a gatekeeper of the mesodermal transcriptional program by local modulation of DNMT3B [human_2] 12.21
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 11.97
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 11.97
Transcriptome Analysis and Functional Identification of Adipose-Derived Mesenchymal Stem Cells in Secondary Lymphedema 11.48
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 11.32
Human iPSC-based Modeling of Late-Onset Disease using Progerin-induced Aging 11.16
Exercise-induced transcriptome changes in skeletal muscle adapted to aerobic training 10.99
DIGIT regulates endoderm differentiation of human embryonic stem cells 10.92
FGF2 regulation of gene expression in stable inducible Neurons 10.83
Chromatin landscape of human visceral and subcutaneous adipocytes 10.72
hiPSCs unravel aberrant TGFβ signaling as an etiology of left ventricular non-compaction 10.71
RNA-seq of naive and primed ES cells (NHSM) 10.7
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 10.59
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells 10.29
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 10.29
Dissecting cell composition and cell-cell interaction network of normal human heart tissue by single-cell sequencing 10.22
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 10.2
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 10.2
LncRNA DEANR1 facilitates human endoderm differentiation by activating FOXA2 expression 10.04
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 9.89
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 9.89
Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model 9.88
9.79
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1 and H1 after SNAI1 deletion at Day2 after human early hematopoietic differentiation . 9.69
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development 9.66
Ectoderm specification of H1 human embryonic stem cells 9.61
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies 9.5
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 9.4
Depicting early human development and germ cell origin with porcine embryos 9.25
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 9.14
Modeling Trilateral Retinoblastoma using Human Embryonic Stem Cells 8.89
Identifying a novel candidate diagnostic and prognostic biomarker SPRR3 for oral squamous cell carcinoma via mRNA Sequencing and Bioinformatics 8.64
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival 8.34
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival [RNA-Seq] 8.34
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 8.18
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 8.13
Genome-wide chromatin analysis of Ewing sarcoma 8.13
ERBB3 and NGFR mark distinct skeletal muscle progenitor cells in human development enabling enrichment and maturation of hPSC muscle 8.09
BI Human Reference Epigenome Mapping Project 8.05
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [H1 RNA-seq] 7.51
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells (Poly(I:C) and LPS) 7.47
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 7.14
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy 6.99
Genome-wide transcriptome analysis of organotypic rafts derived from human papillomavirus type 16 infected primary keratinocytes [3D raft] 6.8
Derivation and differentiation of haploid human embryonic stem cells [RNA-Seq 1] 6.78
Derivation and differentiation of haploid human embryonic stem cells 6.75
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 6.74
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 6.73
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 6.73
Gene expression patterns define the hepatocyte-like cells derived by different strategies 6.64
Gene expression patterns define the hepatocyte-like cells derived by different strategies [RNA-seq] 6.64
Bone marrow-derived and dental pulp-derived human mesenchymal stem cell RNA-Seq 6.63
MYCL and EP400 are required for Max and MCPyV mediated gene activation 6.47
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 1] 6.16
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 6.11
High-Throughput Screening of Human Induced Pluripotent Stem Cell Cardiomyocytes Predicts Tyrosine Kinase Inhibitor Cardiotoxicity 6.09
Tyrosine Kinase Inhibitor Cardiotoxicity 6.09
MEIS1 regulates hematopoiesis in hPSCs 6.01
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 5.94
Mechanosensitive ion channel regulates tissue stiffening to promote glioma aggression 5.94
Preliminary Report of Transplantation of Human Fetal Retinal Pigment Epithelial Cells on Age-related Macular Degeneration Patients 5.83
Epigenetic Inactivation of Cysteine Dioxygenase Type 1 Contributes to ROS-dependent Progression of Colorectal Cancer 5.64
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 5.63
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 5.63
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 5.61
Pericyte-like cells generated from human pluripotent stem cells support hematopoietic stem and progenitors ex vivo 5.6
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression and cell death 5.52
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 5.42
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 5.38
The Unfolded Protein Response Regulator, ATF6, Promotes Mesodermal Differentiation 5.32
The comparison of high-throughput single-cell RNA-seq methods 5.27
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 5.26
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 5.26
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 4.94
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 4.94
RNA-seq characterization of downstream effects of upregulating SMN2 via down-regulating PRC2 or blocking the PRC2:SMN-AS1 interaction with a mixmer oligonucleotide 4.9
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 4.88
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks 4.85
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 4.77
The effect of spontaneous acquisition of an extra chromosome 7 for engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 4.74
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs 4.67
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies 4.63
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies [RNA-Seq] 4.63
Essential Roles of SETD7 as Transcriptional Activator and Co-regulator of H3K36me in Cardiac Lineage Commitment 4.63
Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation 4.59
Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells via Transcription Factor Conversion of Hemogenic Endothelium 4.59
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation, modulates translation and spliceosomal processes 4.54
CUREfast: Accelerating research with families 4.5
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 4.38
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 4.31
Human pluripotent stem cell-derived brain tumor model uncovered embryonic stem cell signature as a key driver in atypical teratoid/rhabdoid tumor (RNA-Seq) 4.23
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 4.23
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells 4.16
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 4.15
RNA-Sequencing shows novel transcriptomic signatures in failing and non-failing human heart 4.15
RNA-sequencing analysis of 5' capped RNAs identifies novel differentially expressed genes in sessile serrated colon polyps (SSPs) 4.15
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination 4.05
Global transcriptome analysis of WT versus HEB-/- hESCs 4.03
FGF2 induces migration of human bone marrow stromal cells by increasing core-fucosylations on N-glycans of integrins 4.01
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor 3.92
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 3.82
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 3.79
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 3.68
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 3.6
Transcriptomic analysis of the effect of trastuzumab in human iPSC-CMs 3.58
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes 3.55
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes [RNA-Seq] 3.55
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 3.4
HNF1 regulates critical functions of the human epididymis epithelium. 3.38
HNF1 regulates critical functions of the human epididymis epithelium. [RNA-Seq] 3.38
Global expression profiles in cardiac progenitor cells generated by ISX-9 3.36
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 3.36
UMI-count modeling and differential expression analysis for single-cell RNA sequencing 3.36
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 3.24
The bromodomain protein BRD4 regulates splicing during heat shock 3.24
Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells 3.14
Meta-organization of Translation Centers Revealed by Proximity Mapping of Endoplasmic Reticulum Ribosome Interactors 3.1
Long non-coding RNA expression profile associated with malignant progression of oral submucous fibrosis 3.08
POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells 3.08
PAX3-FOXO1 requires BRD4 to drive oncogene addiction in RMS cells [RNA-seq] 3.08
Epigenetic Lanscape and BRD4 Transcriptional Dependency of PAX3-FOXO1 Driven Rhabdomyosarcoma 3.08
Antiviral innate immunity of hepatitis C virus-infected stem cell-derived hepatocytes 3.06
Transcriptomic Dynamics during Differentiation Process of Human Pluripotent Cells into Hepatocyte-like Cells 3.05
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 3.04
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq Human] 3.03
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 3.02
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 3.02
RNA-seq analysis of RALD iPSCs after in vitro differentiation 2.9
MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block 2.9
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition 2.9
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 2.85
DART-seq: an antibody-free method for global m6A detection 2.84
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity 2.78
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 2.73
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 2.73
Characterization of Type I Interferon pathway during Hepatic Differentiation of Human Pluripotent Stem Cells and hepatitis C virus infection 2.67
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons 2.6
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons [RNA-seq] 2.6
RNA-seq analysis of A2780 and OVCAR3 human ovarian cancer cell lines after overexpression of collagen type XI alpha 1 (COL11A1) 2.55
CHD1 regulates cell fate determination by activation of differentiation-induced genes 2.52
Maturing an Enteric Nervous System in Human Intestinal Organoid-derived Tissue-Engineered Small Intestine 2.49
De novo reconstruction of human adipose reveals conserved lncRNAs as regulators of brown adipogenesis 2.43
Reconstitution of the human pancreatic niche stimulates differentiation of hESCs into beta cells and reveals new signals for pancreatic endocrine cell maturation 2.42
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 2.41
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 2.4
Transcriptome changes due to nuclear penetration of cancer extracellular vesicles 2.39
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 2.39
Analysis of transcrptomes of Danon patient derived hiPSC-cardiomyocytes by RNA-deep Sequencing 2.36
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens [RNA-Seq] 2.35
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens 2.35
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation 2.35
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation (RNA-Seq) 2.35
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 2.34
PRRX2 and HEY2 double knock-down facilitates ASCL1-induced neuron conversion in human dermal fibroblasts. 2.28
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors 2.22
Distinct Pathological Signatures in Human Cellular Models of Myotonic Dystrophy Subtypes 2.12
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 2.03
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 2.01
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes 2.01
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration [RNA-seq2] 2.01
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 2.0
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 1.99
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 1.99
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 1.99
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+ T regulatory cells activation 1.97
Oncogenic Serine-Threonine Kinase Receptor Associated Protein Supports Hepatocellular Carcinoma Cell Growth by Enhancing Wnt/β-catenin Signaling 1.96
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 1.94
Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes 1.92
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer 1.91
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer [RNA-Seq] 1.91
Effect of selective glucocorticoid receptor modulation (SGRM) on gene expression in human prostate cancer cell lines 1.91
Differetially expressed genes after hTR overexpression in U2OS cells 1.89
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 1.84
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates 1.84
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 1.83
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 1.83
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 1.82
Comparative Transcriptomics of Triple Negative Breast Cancer Stem Cells and Differentiated Tumor Cells Identifies Teneurin-4 as a Potential Therapeutic Target 1.82
RNA-seq of human iPS derived macrophages with or without KLF1- transcription factor Activation 1.82
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration 1.81
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 1.81
Gene expression profiling of human and murine in vitro muscle differentiation 1.79
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 1.79
PRDM1 inhibits proliferation of human colon cancer organoids 1.79
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 1.73
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 1.72
Next Generation Sequencing Analysis of human embryonic stem cells derived MESP1-mTomato reporter cells 1.72
Gene expression profile of HGC27 and LMSU gastric cancer cell p53 KO and KD 1.66
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 1.66
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 1.65
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_RNA-seq] 1.65
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 1.63
Global gene expression profiles of cardiomyocytes differentiated from human pluripotent stem cells (hiPSC-CMs) in 3D culture exposed to ethanol 1.62
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT, U0126, CYHX, ActD, EGF, FGF, or IGF and labelled with 4SU 1.62
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT and labelled with 4SU 1.62
SETBP1-WT and SETBP1-G870S epigenetic landscapes 1.61
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 1.61
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency 1.6
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency [RNA-Seq] 1.6
RNA profiling Analysis of the Serum Exosomes Derived from Active and Latent M.tuberculosis infectious Patients 1.59
Next Generation Sequencing Facilitates Quantitative Analysis of Human Pluripotent Stem Cell-Derived Endocardial-like And Primary Cardiac Endothelial Cell Transcriptomes 1.59
Organoids derived from directly reprogrammed human hepatocytes for modeling liver cancer initiation 1.59
Reciprocal Reprogramming of Cancer Cells and Associated Mesenchymal Stem Cells in Gastric Cancer. 1.58
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 1.58
Characterization and therapeautic application of mesenchymal stem cells with neuromesodermal origin from human pluripotent stem cells 1.56
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation 1.54
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq] 1.54
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells 1.52
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors 1.5
Prostaglandin E2 inhibits pro-fibrotic function of human pulmonary fibroblasts by disrupting Ca2+-signaling 1.5
Reprogramming postnatal human epidermal keratinocytes toward functional neural crest fates 1.48
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7 1.48
Lineage specific differentiation is influenced by state of human pluripotency [RNA-seq] 1.47
Lineage specific differentiation is influenced by state of human pluripotency 1.47
MOV10 Is a 5' to 3' RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3'UTRs 1.45
MOV10 Is a 5' to 3' RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3'UTRs (expression) 1.45
Transcriptome of human white and brown adipose tissue biopsies 1.44
RNA Seq analysis of NKX2-5 Null and Het human embryonic stem cells in cardiomyogenesis 1.44
RNA-sequencing of formalin fixed human primary melanoma tissue 1.43
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 1.42
Whole transcriptome RNA sequencing of human cells after HCV infection (ML-1 thyroid cell line, primary thyrocytes and Huh7.5 hepatocyte cell line) 1.4
Transcriptional profiling of LS1034 cells treated with tepoxalin 1.37
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 1.34
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 1.34
RNA-seq in endometrial stromal tumors 1.34
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 1.33
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 1.33
Transcriptome analysis of H9 hESC derived cerebral organoids 1.33
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells (RNA-seq) 1.32
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells 1.32
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 1.29
Gene expression analysis of human adenomas. 1.28
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq 1.27
Global transcriptional analysis and genome-wide analysis of chromatin state in extended pluripotent stem cells, primed pluripotent stem cells, and naïve pluripotent stem cells 1.27
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation (RNA-seq) 1.27
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation 1.27
Dual role of CSL (RBP-Jk) and NOTCH1 in cancer-associated fibroblast genome stability and expansion [RNA-seq] 1.23
Dual role of CSL (RBP-Jk) and NOTCH1 in CAF 1.23
Defining a microRNA-mRNA targetome for calcineurin inhibitor induced nephrotoxicity 1.23
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 1.22
RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS mutant colorectal cancer 1.21
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 1.21
Dynamic epigenetic remodeling underlies microRNA-mediated transdifferentiation of human adult fibroblasts into neuronal subtypes 1.19
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells [RNA-seq] 1.19
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells 1.19
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 1.19
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 1.19
Molecular Criteria for Defining the Naive Human Pluripotent State 1.18
Glucose inhibits cardiac maturation through nucleotide biosynthesis 1.17
Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype 1.16
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 1.16
RNA-Seq of human induced pluripotent stem cell-derived cardiomyocytes from a cardiomyopathy patient and familial control 1.15
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 1.14
The control of rRNA synthesis during the directed differentiation of human embryonic stem cells precedes heterochromatin formation. 1.13
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 1.12
Epigenome regulation during epidermal lineage commitment [RNA-seq] 1.11
Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9 1.1
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 1.07
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 1.06
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function 1.06
Mammalian Hbs1L deficiency causes Pelota depletion and is associated with a unique phenotype 1.04
Dissecting cell composition and cell-cell interaction network of human disease heart tissue by single-cell sequencing 1.04
Transcriptome profiling of a mouse model of alveolar soft part sarcoma 1.03
RNAseq of quiescent (Q) and stress induced premature senescent (SIPS) fibroblasts treated with plant extract (1201) from Solidago vigaurea subspecies alpestris 1.03
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of human mesenchymal stem cells differentiation from human embryonic stem cells and adult bone marrow mesenchymal stem cells 1.02
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 1.02
G-quadruplex structures mark human regulatory chromatin 1.0
FMR1 reactivating treatments in Fragile X iPSC-derived neural progenitors in-vitro and in-vivo 0.99
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 0.99
Long non-coding RNA SMILR regulates genes involved in cytokinesis in human vascular smooth muscle cell 0.99
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 0.98
Transcriptional profile of CAOV2 ovarian cancer cells with TAZ silencing 0.98
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes 0.97
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes (RNA-Seq) 0.97
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 0.97
Efficient direct reprogramming of c-Kit− mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression 0.97
Molecular analysis of renal cell carcinoma with unclassfied histology 0.96
Molecular analysis of renal cell carcinoma with unclassfied histology [gene expression] 0.96
Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways 0.96
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules 0.96
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules [gene expression] 0.96
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 0.95
High-efficiency RNA-based reprogramming of human primary fibroblasts 0.94
Next-generation sequencing of human dermal fibroblasts transdifferentiated towards the otic lineage 0.94
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 0.93
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 0.93
Robust generation of honemogeneous midbrain organoids with in vivo–like cellular composition facilitates neurotoxin-based Parkinson’s disease modeling 0.93
Next Generation Sequencing of human SMA and healthy control Motor Neurons 0.92
Reassessment of Exosome Composition 0.92
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 0.92
ZRANB2 and SYF2 mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin 0.91
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 0.91
Impact of HypERrlnc Knockdown on the human pericyte transcriptome 0.9
RNA Sequencing Analysis of villus tissues from unexplained recurrent spontaneous abortion patients and controls with induced abortions 0.9
Transcriptome profiles of moderate dysplasia in oral mucosa associated with malignant conversion 0.9
Gene expression profiles of ibrutinib-responsive and ibrutinib non-responsive cells in ERBB4 expressing cancer cell lines 0.89
An electrical pulse stimulation protocol to study acute epigenetic response to muscle cell contraction uncovers acute hydroxymethylation of the exercise-responsive gene Nr4a3 [RNA-Seq] 0.88
An electrical pulse stimulation protocol to study acute epigenetic response to muscle cell contraction uncovers acute hydroxymethylation of the exercise-responsive gene Nr4a3 0.88
RNA-SEQ assay for wild type and CRISPR induced endoglin knockout human pulmonary artery smooth muscle cells (PASMC) 0.88
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 0.88
RNA-seq identifies novel lncRNAs involved in vascular smooth muscle cell proliferation 0.87
Global analysis of alternative splicing regulated by RBM10 0.86
Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis 0.86
Kidney organoid reproducibility across multiple human iPSC lines and diminished off target cells after transplantation revealed by single cell transcriptomics 0.85
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 0.84
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 0.84
Differential gene expression analysis between proliferating and quiescent human dermal fibroblasts 0.84
Histone deacetylase inhibition enhances antimicrobial peptide but not inflammatory cytokine expression upon bacterial challenge 0.83
Genetic and Epigenetic Landscapes of Laterally Spreading Tumors of the Colorectum 0.82
The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma [RNA-Seq Tumor] 0.81
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.81
A20 regulates canonical wnt-signaling through an interaction with RIPK4 0.81
RNA-seq analysis of HT-29, MCF10A, and MDA-MB-436 cells 0.81
Transcriptional landscape changes during human embryonic stem cell derivation 0.8
RNA-Seq profiling of iPSC-derived ventricular and atrial cardiomyocytes 0.8
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation 0.78
Histone H3.1K27 methylation promotes NHEJ by antagonizing FANCD2 on Chromatin 0.78
Region-specific Innate Antiviral Responses of the Human Epididymis 0.77
RNAseq data from Mesenchymal stem cells treated with TCDD or 1-methyl tryptophan 0.77
Microglia innatly develop within cerebral organoids 0.73
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 0.72
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 0.71
Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium 0.71
Effect of estrogen (E2) treatment on the C4-12 relative to the MCF7 cells 0.7
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 0.68
High-throughput sequencing of pluripotent cells 0.66
Identification of long noncoding RNAs regulated by p53 0.64
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 0.64
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 0.64
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 0.64
Engineering Patient-Specific Tissue Implants 0.64
RNA-sequencing with micro-dissected boundary organoid into anterior, posterior, and boundary regions 0.64
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency 0.64
A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis 0.63
Whole genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver 0.62
Whole genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver [RNA-Seq] 0.62
Human serum and heparin-free platelet lysate as appropriate xeno-free alternatives for production of human MuStem cell batches 0.61
A transcriptome-wide divergence in protein translation scales with LIN28B expression 0.6
RNA-seq of exosomes identifies lncRNA profiles that distinguish early-stage esophageal squamous cell carcinoma (ESCC) from non-malignant esophagitis 0.6
Human naïve pluripotent stem cells exhibit X chromosome dampening and X-inactivation (RNA-Seq) 0.6
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 0.59
Reprogramming of Tumor-infiltrating Immune Cells in Early Stage of NSCLC 0.59
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 0.59
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 0.59
iPSC-Derived Cholangiocytes 0.58
Controlling for gene expression changes in transcription factor protein networks. 0.57
Subtle asymmetry of gene expression in embryonic and foetal human brains 0.56
RNA-sequencing of healthy human skeletal myocytes 0.55
Functional Haploid Human Oocytes Generated from Polar Body Genomes (RNA-Seq) 0.55
Functional Haploid Human Oocytes Generated from Polar Body Genomes 0.55
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 0.54
Effects of a nutritional supplement in older individuals subject to ten days of complete bed rest. 0.53
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 0.52
Single-Cell Transcriptome Analysis of Lineage Diversity and Microenvironment in High-Grade Glioma 0.52
Epigenome regulation during epidermal lineage commitment 0.52
Generation of trichogenic adipose-derived stem cells by expression of three factors 0.51
mRNA expression data from ESCs derived by polar body transfer reconstructed embryos (PBTESCs) 0.51
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 0.5
RNA Sequencing of Human iPS derived Cardiomyocytes 0.48
Gene expression in skeletal muscle in older individuals subject to ten days of complete bed rest. 0.48
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis 0.46
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis [bulk RNA-Seq] 0.46
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 0.44
Isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 0.43
CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 0.43
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 0.43
The global transcriptome analysis in the time course of hESC-derived cardiac differentiation 0.42
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 0.41
Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability? 0.4
A runaway PRH/HHEX-Notch3 feedback loop drives cholangiocarcinoma (RNA-Seq) 0.4
Analysis of MGE Transcriptomes with or without Ctnnb1 knockout in human through RNA Sequencing 0.4
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 0.39
Reprogramming of dermal papilla cell intact gene signature with 3D culture and Lef-1 overexpression 0.39
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [RNA-Seq] 0.39
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis 0.39
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells [RNA-Seq] 0.38
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells 0.38
A myogenic double reporter human pluripotent stem cell line allows prospective isolation of skeletal muscle progenitors 0.37
Comparative analysis of kidney organoid and adult human kidney single cell and single nucleus transcriptomes 0.37
ENCODE Cold Spring Harbor Labs Long RNA-seq 0.37
A549 cell transcriptome responses to infection with H7N9 influenza virus 0.37
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 0.37
Transcriptome-analysis of patient-derived normal and ulcerative colitis intestinal epithelial organoids 0.36
Human Induced Pluripotent Stem Cells Recapitulate Breast Cancer Patients’ Predilection to Doxorubicin-Induced Cardiotoxicity 0.34
Transcriptomic profiling of mesenchymal stem cells (MSC) differentiation into mesangial cells 0.34
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 0.33
Hemogenic Endothelium transcriptome along the timeline of hESC differentiation 0.33
Impeding transcription of expanded microsatellite repeats by deactivated Cas9 0.32
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes 0.32
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 0.32
Generating Patterned Kidney Organoids for Studying Development and Diseases 0.29
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 0.29
CDK12 mediated transcriptional regulation in U2OS cells 0.29
Integrated Multi-omic Analysis of Esthesioneuroblastomas Identifies Two Subgroups Linked to Cell Ontogeny 0.26
SF3B1 Degron knockdown RNA-seq 0.26
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 0.25
Generating Patterned Kidney Organoids for Studying Development and Diseases [bulk RNA-Seq] 0.25
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 0.25
Expression profiles of cultured human epididymis cells reveal the functional diversity of caput, corpus and cauda regions. 0.24
SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF 0.23
RNA sequencing of CACO-2 cells incubated with bifidobacteria grown on human milk oligosaccharides. 0.23
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 0.21
Assessing placental maturity through histological and transcriptomic analyses in idiopathic spontaneous preterm birth 0.21
Identification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq 0.21
Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells 0.2
Transcriptome profiling in primary human skeletal myotubes with MondoA knockdown 0.19
MondoA Links Muscle Lipid Accumulation and Insulin Resistance Driven by Nutrient Overload 0.19
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HOM] 0.19
Modeling Human Cancer-induced Cachexia (Human) 0.18
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 0.17
Early transcriptome profiling of microRNA-mediated neuronal reprogramming [RNA-seq timecourse] 0.14
Evaluation of the effectiveness of semen collection and sperm purification methods for spermatozoa transcript profiling 0.14
Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes 0.13
Genome wide transcript and miRNAanalysis of invitro and in-vivo generated human cardiac samples 0.13
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [RNA-Seq III] 0.13
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 0.12
RNA-seq of cancer cell lines treated with T-025 0.12
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.11
Human ES Cell-derived Hepatoblasts are an Optimal Lineage Stage for HCV Infection 0.11
RNA-sequencing analysis examining how the Vibrio cholerae MARTX toxin and its inidividual effector domains modulate the transcriptome of human intestinal epithelial cells. 0.11
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 0.11
Human colon organoids reveal distinct physiologic and oncogenic Wnt responses 0.11
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 0.11
Deep sequencing of transcript levels of human embryonic stem cell derived mesothelium (epithelial and mesenchymal forms) and mesothelium from neonatal mouse E15.5 of the heart, lung, liver and gut and ChIP-seq data of the mesenchymal form of mesothelium 0.11
The phosphatidylinositol 3-kinase pathway as a potential therapeutic target in bladder cancer 0.1
Identification of Atrial Fibrillation associated genes and functional non-coding variants 0.09
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 0.09
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 0.08
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 0.08
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 0.07
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 0.07
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 0.07
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 0.06
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 0.06
Methylome, hydroxymethylome, and integrative transcriptome profiling in human CRC tissue and paired normal tissues 0.06
A systematic analysis of the time series gene expression in TGF-beta induced EMT by Next-generation sequencing 0.06
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 0.05
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 0.05
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 0.05
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 0.05
Screening in Human Cardiac Organoids Identifies a Requirement for the Mevalonate Pathway in Cardiomyocyte Proliferation 0.05
Single-Cell reconstruction of differentiation trajectory reveals essential dynamics in human cardiac lineage commitment 0.04
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease (human) 0.04
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease 0.04
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 0.03
Fixed tissue ChIP-Seq (FiT-Seq) of archived clinical samples reveals chromatin dynamics and tumor-specific enhancer profiles 0.02
Muscle transcriptome analysis following Total Knee Arthroplasty with Tourniquet 0.02
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 0.01
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 0.01
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 0.01
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 0.0


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