Gene Query: PLEKHG4

Dataset Description Geneva Score
Genome wide expression change in LCC2 and MCF-7 cells 73.22
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 70.42
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 46.67
Gene Expression Profiling of SPOP Knocked Down Cell 39.71
Estrogen receptor and mTOR signaling rewires cancer metabolism in obesity-associated breast cancer 37.36
Pharmacologic inhibition of STAT5 in AML 36.16
ARS2 is a general suppressor of pervasive transcription [RNAseq] 33.03
Mutational landscape of splicing genes and functional consequences across 33 cancer types 32.54
Improved post thaw function and genetic changes for mesenchymal stromal cells cryopreserved using multicomponent osmolyte solutions 32.11
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived SPINK1 31.88
Transcriptome of human keratinocytes with or without HPV16 oncogene expression 26.89
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 26.08
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 25.57
Integrated Systems Biology Analysis of KSHV Latent Infection Reveals Viral Induction and Reliance on Peroxisome Mediated Lipid Metabolism 24.63
Lysine benzoylation is a novel histone mark [RNA-seq] 24.23
Lysine benzoylation is a novel histone mark 24.23
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 24.02
Tamoxifen Resistance in Breast Cancer is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis 23.13
Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance 22.31
ZRANB2 and SYF2 mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin 21.45
RNAseq of T-ALL upon long non coding rna purturbation 21.4
IRF2 is a master regulator of human keratinocyte stem cell fate 21.13
IRF2 is a master regulator of human keratinocyte stem cell fate [RNA-seq] 21.13
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 20.93
Identification of ZEB1-regulated gene expression changes in HCC827 human lung adenocarcinoma cells 20.64
RNA-seq analysis of AML cells in response to ASLAN003 20.05
Effect of SHP2 inhibition on hepatic stellate cell transcriptome. 19.93
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 19.46
RNA expression analysis of neuroblastoma cell lines treated with epigenetic drugs 19.38
WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription 19.2
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 18.22
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 18.22
Gene expression analysis in U251 and U87 cells transduced with NANEP5 vector. 17.68
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma 17.66
Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer 16.94
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 16.74
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 16.59
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 16.42
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 16.42
Transcriptome analysis of U87 cells upon LINC00152 knockdown 16.23
NOTCH signaling is activated in and contributes to resistance in enzalutamide-resistant prostate cancer cells 15.66
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 15.35
Global transcriptional profiling changes upon knockdown of LKB1 in human glioblastoma cell lines 15.12
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 14.95
Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence 14.89
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 14.84
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 14.6
RNA-seq of MDA-MB-231 cells with TET1 knockout 14.4
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression 14.37
Genome-wide CRISPR-Cas9 screen identifies SLC1A3 as a key contributor to L-asparaginase Resistance in Solid tumors 14.31
Gene expression changes associated with resistance to tagraxofusp (SL-401) 14.27
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 14.07
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 13.98
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 13.83
Preliminary Report of Transplantation of Human Fetal Retinal Pigment Epithelial Cells on Age-related Macular Degeneration Patients 13.8
Differentially expressed (DE) genes analysis in synovial fluid mesenchymal stem cells (SF-MSCs), SF-MSC derived iPSCs and iPSC derived MSCs (iPSC-MSCs) 13.75
Gene expression changes in human melanoma cell lines compared to primary melanocytes 13.74
Identification of a core p53 transcriptional program with highly fractionated tumor suppressive activity 13.41
GRO-seq from HCT116, MCF7 and SJSA cell lines treated with DMSO and Nutlin 13.41
RNA-seq Analysis of Castration-Resistant Prostate Cancer With Knock-down of E2F1 13.41
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 13.38
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq] 13.38
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 13.27
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 13.2
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 13.09
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 13.09
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 13.09
Transcriptome analysis in HT29 and SW480 cells depleted of Prdx2 12.94
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation 12.84
ChIP-seq of ER and RUNX2 in MCF7 breast cancer cell lines 12.79
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 12.72
Defining a microRNA-mRNA targetome for calcineurin inhibitor induced nephrotoxicity 12.66
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 12.61
LncRNA NONHSAT113026 represses renal cell carcinoma tumorigenesis through interacting with NF-κB/p50 and SLUG 12.59
A sister of NANOG regulates genes expressed in pre-implantation human development 12.53
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 12.29
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 12.29
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 12.17
Transcriptome profiling of influenza virus-infected human bronchial epithelial cells 11.96
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 11.79
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not 11.49
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 11.43
Transcriptomic profiling of human coronary artery endothelial cells under laminar shear stress (LS), oscillatory shear stress (OS) and static culture (ST) 11.37
mRNA Profiling of miR-17 family inhibition using TuD lentiviral vector in HepG2 and SK-Hep1 hepatocellular carcinoma cell lines [RNA-Seq] 11.29
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth 11.29
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 11.26
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 11.26
Global gene expression differences between blood- and lymphatic-specific endothelial colony forming cells 11.18
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 11.17
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 10.94
Mastermind-like 3 controls proliferation and differentiation in neuroblastoma (RNA-seq) 10.89
Mastermind-like 3 controls proliferation and differentiation in neuroblastoma 10.89
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 10.87
EWSR1 influences alternative splicing through direct and indirect mechanisms 10.83
Global Gene Expression Changes in Cholangiocytes Treated with TGF-beta 10.77
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  10.76
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 10.66
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 10.66
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq] 10.56
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation 10.56
IDH3a KO RNA-seq 10.5
Biological effect of chronic mistranslation in mammalian cells 10.48
Transcriptome of EBV-infected gastric cancer cell lines 10.37
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 10.29
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 10.26
Characterization of parental and rociletinib-resistant derived H1975 cell lines 10.25
RNA-seq of young and quiescent MRC-5 human fibroblasts 10.24
Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation 10.22
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways [RNA-seq] 9.97
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways 9.97
Universal alternative splicing of noncoding exons 9.96
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 9.91
Hijacking of stress response machinery by oncogenes in acute leukaemia 9.91
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 9.73
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 9.59
Sequence dependency and regulatory function of dimeric NOTCH1/RBPJ complexes on coding and non-coding transcription in T-lymphoblastic leukemia 9.56
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 9.53
The effect of PPARG inhibition on human angiomyolipoma cells 9.53
Novel mutations segregating with Complete Androgen Insensitivity Syndrome and their molecular characteristics. 9.5
Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures 9.48
Identification of the role of polydom in neurofibromas 9.45
Metastasis in triple negative breast cancer is dependent on ΔNp63/CXCL2/CCL22-mediated recruitment of myeloid-derived suppressor cells 9.44
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 9.4
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with tcons_00001221 shRNA or control shRNA 9.38
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreas cancer 9.37
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 9.26
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 9.26
Expression data from human perivascular stem cell-derived extracellular vesicles (PSC-EVs) and PSCs 9.21
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 9.18
The DNM3OS lncRNA is a reservoir of fibromiRs with major functions in fibroblast response to TGF-beta and fibrogenesis 9.13
RNA-Seq analysis of human lung fibroblasts exposed to TGF-β 9.13
Gene expression profile using RNA-seq in WC00060 or SR-0788 cells transfected with siRNA for KPC1 or control 9.07
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 9.07
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 9.05
Random mono-allelic expression in MECP2-mutated cells 9.04
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell type specificity 8.99
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 8.95
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 8.95
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 8.92
Generation of trichogenic adipose-derived stem cells by expression of three factors 8.9
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 8.85
Identification of the O-GlcNAc-regulated alternative splicing events by performing RNA sequencing on HeLa cells with altered O-GlcNAc level. 8.8
RNA expression following TMPRSS11B overexpression or depletion 8.73
RNA-seq of cancer cell lines treated with T-025 8.71
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 8.64
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 8.62
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 8.62
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 8.61
Effect of BRCA1 overexpression on genetic expressions of cervical cancer based on next generation sequencing 8.61
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 8.56
RNA-Sequencing data of Varicella Zoster Virus (VZV)-infected human dermal fibroblasts (HDF) 8.33
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 8.29
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 8.29
GATA3-mediated chromatin reprogramming in breast cancer cells 8.26
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 8.25
Ligand-dependent genomic function of glucocorticoid receptor in triple-negative breast cancer 8.18
Glioblastoma stem cells infected by ZIKA virus 8.05
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 7.92
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 7.85
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 7.84
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 7.84
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 7.8
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes 7.76
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes (RNA-Seq) 7.76
EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC 7.75
Differential expression in wild-type and mutant neurofibroma and MPNST cell lines 7.67
Neurofibroma 7.67
Downregulation of DDX5/DDX17 and REST 7.65
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 7.58
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 7.57
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 7.55
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 7.55
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 7.54
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 7.51
Prostate Cancer Cell RNA-Seq (PC3E and GS689.Li) 7.46
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 7.4
Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells 7.4
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer 7.32
Genome-wide functional assessment of enhancer activities in the human genome 7.3
RNA-seq of PC3 prostate cancer cell line xenografts in mice administered the ghrelin receptor antagonist [D-Lys3]-GHRP-6 or PBS for two weeks 7.25
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 7.24
Loss of CHD1 facilitates oncogenic hijacking of AR during cancer progression 7.21
Loss of CHD1 facilitates oncogenic hijacking of AR during cancer progression [RNA-seq] 7.21
Controlling for gene expression changes in transcription factor protein networks. 7.2
Paxillin regulates genomic networks in prostate cancer [C4-2] 7.18
Prostaglandin E2 inhibits pro-fibrotic function of human pulmonary fibroblasts by disrupting Ca2+-signaling 7.07
GATA3 enhances the neurogenic potential of primary human astrocytes after traumatic injury [exp2] 7.04
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (22RV1 RNA-seq) 7.03
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability 7.03
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 6.98
RNA sequencing of human fibroblasts after SUPT4H1 siRNA treatment 6.97
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 6.95
Epidermal growth factor activates β-catenin via integrin-linked kinase to control proliferation of mesenchymal stromal cells. 6.94
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 6.93
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer [RNA-Seq] 6.91
UBR7 is a novel E3 ubiquitin ligase for H2BK120 and acts as a tumor-suppressor in breast cancer 6.91
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 6.83
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 6.83
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 6.82
Expression changes in melanoma cell lines pre MAPKi treatment vs. post-MAPKi resistance (RNA-seq_CellLine.batch2) 6.8
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 6.73
In vivo genome editing restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers 6.71
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 6.7
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery 6.7
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery (RNA-seq data set) 6.7
snRNAs as regulators of alternative splicing 6.64
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 6.58
Effect of mitochondria deficiency on senescence-associated gene expression 6.55
RNA-seq of human aneuploid cell lines with Trisomy 21 6.48
RNA-seq analyisis of PUM2 knockout cells 6.46
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 6.46
Identification of global regulators of T-helper cell lineage specification 6.46
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development 6.44
Multivalent binding of PWWP2A to H2A.Z-marked transcriptional active chromatin regulates mitosis and organ development [RNA-seq] 6.44
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 6.37
AR-independent prostate cancer is sustained through FGF signaling 6.31
miRNAs affected by antagomiR-17 treatment 6.28
The Polycomb protein BMI1 induces an invasive gene expression signature in melanoma that promotes metastasis and chemoresistance. 6.25
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 6.25
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 6.25
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 6.25
Chromatin landscape of human visceral and subcutaneous adipocytes 6.21
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export II 6.19
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 6.17
High-depth RNA sequencing of isogenic wild-type, PIK3CA-WT/H1047R and PIK3CA-H1047R/H1047R human iPSCs 6.17
Targeting MTHFD2 in Acute Myeloid Leukemia 6.16
ARID1A and ARID1B loss in HCT116 cells 6.11
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq 6.1
Global transcriptional analysis and genome-wide analysis of chromatin state in extended pluripotent stem cells, primed pluripotent stem cells, and naïve pluripotent stem cells 6.1
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 6.07
DART-seq: an antibody-free method for global m6A detection 6.05
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 6.02
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB 6.02
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 6.01
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 5.99
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 5.99
The cytokine environment influence on human skin-derived T cells 5.96
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 5.96
RNA-seq of YB5 cells treated with Proscillaridin A 5.91
Splicing and gene expression changes in human mammary epithelial MCF-10A cells expressing SR or SR-like proteins 5.9
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 5.89
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 5.89
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 5.88
CDK4/6 inhibitor resistance in prostate cancer 5.85
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 5.84
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 5.81
Transciptomic profiling of human fetal lung samples 5.81
RNA-seq of tumor cells following angiopellosis extravasation 5.79
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [RBM47 KD] 5.72
Integrative Genomic and Transcriptomic Analysis Identified Candidate Genes Implicated in the Pathogenesis of Hepatosplenic T-cell Lymphoma 5.7
Hepatosplenic T cell lymphoma 5.7
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 5.69
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 5.69
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 5.64
RNA-seq analysis of SKMEL28 melanoma cells following DIRC3 and IGFBP5 ASO knockdown 5.64
Chromatin-informed inference of transcriptional programs in gynecologic cancers 5.58
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 5.58
Whole transcriptome RNA sequencing of human cells after HCV infection (ML-1 thyroid cell line, primary thyrocytes and Huh7.5 hepatocyte cell line) 5.57
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 5.55
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates 5.53
Gene Expression Profiling of WT and KDM3A Knocked out Cell 5.52
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 5.52
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 5.51
Effector and regulatory T cells roll at high shear stress by inducible tether and sling formation 5.5
Specific inhibition of DPY30 activity by peptides suppresses blood cancer cell growth 5.49
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 5.48
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  5.47
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 5.45
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 5.45
Targeted enhancer activation by a subunit of the integrator complex 5.41
TGF-β promotes genomic instability after loss of RUNX3 5.41
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 5.37
Fbxo32 mediated gene expression program underlies EMT and metastasis 5.35
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 5.32
Transcriptome Analysis and Functional Identification of Adipose-Derived Mesenchymal Stem Cells in Secondary Lymphedema 5.32
MYC dependent mRNA translation shapes gene expression and cell biology 5.28
PRDM1 inhibits proliferation of human colon cancer organoids 5.26
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 5.25
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 5.2
5.19
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 5.18
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected EVT cells 5.12
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 5.11
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells 5.06
HEK293 TFAM Knockout Expression Study 5.05
Whole transcriptome splicing analysis in isogenic lung epithelial and adenocarcinoma cell lines with or without a recurrent splicing factor mutation, U2AF1 (S34F) 4.94
CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells 4.94
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 4.88
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 4.86
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 4.83
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 4.75
Silencing SPIB in attached and floating state of H1703 lung cancer cells 4.71
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 4.69
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 4.68
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 4.59
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 4.58
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 4.58
RNA-seq characterization of downstream effects of upregulating SMN2 via down-regulating PRC2 or blocking the PRC2:SMN-AS1 interaction with a mixmer oligonucleotide 4.47
ELP1 splicing correction reverses proprioceptive sensory loss in familial dysautonomia 4.46
RNA profiling Analysis of the Serum Exosomes Derived from Active and Latent M.tuberculosis infectious Patients 4.36
RNA sequencing of primary human platelets and in vitro cell lines 4.34
Nascent RNA Sequencing after NMYC activation in SH-EP MYCNER cells 4.33
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 4.33
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 4.33
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 4.31
Cell responses to dysregulated VZV-induced cell-cell fusion 4.31
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 4.29
Profiling of circular RNAs in gastric cancer tissues and adjacent normal tissues 4.28
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 4.25
Mesenchymal stem/stromal cell engulfment reveals metastatic advantage in breast cancer 4.23
Entrectinib Resistance in a Neuroblastoma Xenograft Model 4.19
Widespread Transcription beyond mRNA 3’ Ends Yields Abundant Regulatory RNAs 4.17
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation 4.16
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Human_RWPE1_RNA-Seq) 4.16
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer 4.16
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer [RNA-Seq] 4.16
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 4.08
Next Generation Sequencing of human SMA and healthy control Motor Neurons 4.08
Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation 4.08
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L 4.05
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance 4.05
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 4.04
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 4.04
Leucegene: ALL sequencing 4.0
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray 3.98
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray [RNA-Seq] 3.98
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 3.95
Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells. [RNA-Seq - ex vivo] 3.95
Novel Non-catalytic Substrate-selective p38α-specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-inflammatory Activity 3.94
Expression profiling by high throughput sequencing of tumors derived from human prostate epithelial cells transformed with the oncogenes N-Myc and myrAKT1. 3.91
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 3.8
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 3.69
RNA Sequencing of three pairs of gastric cancer 3.69
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 3.67
Fixed tissue ChIP-Seq (FiT-Seq) of archived clinical samples reveals chromatin dynamics and tumor-specific enhancer profiles 3.64
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells 3.61
Long non-coding RNA TYKRIL controls pericyte function and survival in the cardiovascular and central nervous system through regulation of p53 activity and PDGFRß expression 3.58
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 3.58
Transcriptomic analysis of senescent cells upon EXOC7 knockdown. 3.54
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 3.47
Regulation of poly(A) tail and translation during the somatic cell cycle 3.46
KLF6-dependent transcription in renal cancer cells 3.4
High-throughput RNA sequencing on circular RNA profiles of human bladder cancer tissues and normal bladder tissues 3.33
Generation of Patient-Matched Malignant and Normal Primary Cell Cultures from Clear Cell Renal Cell Carcinoma Patients 3.32
HeLa transcriptome induction by IFN gamma and indoleamine 2,3-dioxygenase (IDO) 3.29
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 3.2
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 3.18
The effect of insulin on mRNA transcription of human pluripotent stem cells 3.18
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 3.15
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 3.14
Landscape of human mast cell chromatin: a rich resource for identification of novel mediators and genetic drivers of allergic and inflammatory diseases 3.13
Transcriptomic profiling of human CD34+ derived mast cells [RNA-Seq] 3.13
The role of the Calcium-Sensing receptor in colorectal cancer 3.08
Investigate A2M treatment on human prostate cancer and mouse liver 3.07
Investigate A2M treatment on human prostate cancer xenograft in mice 3.07
Bone marrow-derived and dental pulp-derived human mesenchymal stem cell RNA-Seq 3.04
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 3.03
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 3.0
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 2.96
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 2.96
Human colon organoids reveal distinct physiologic and oncogenic Wnt responses 2.9
High-throughput RNAi cell viability screen to identify selective targets for EWS-FLI1 positive Ewing sarcoma 2.86
The conserved transcriptional landscapes in human spermatogenesis 2.86
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 2.8
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency [RNA-Seq] 2.79
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency 2.79
RNA-seq of cells with TET1 knockout 2.79
Transcriptome profiling of 5 human adenocarcinoma cell lines 2.79
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 2.78
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 2.78
Expression alterations induced by restoration of AXIN1 expression in SNU449 hepatocellular carcinoma cells 2.77
The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing [RNA-seq] 2.72
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HOM] 2.71
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 2.63
Gene expression of thyroid cancer cell lines 2.57
Integrated high-throughput screen to identify novel treatment leads for pediatric acute myeloid leukemia (AML) 2.56
RNA seq_PDX2_SHP099 2.56
Genome-wide analyses of chromatin state in human mast cells reveal molecular drivers and mediators of allergic and inflammatory diseases 2.54
Transcriptomic profiling of human peripheral blood-derived mast cells 2.54
Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration 2.53
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 2.49
RNA sequencing of human pancreatic cancer cell lines 2.47
Gene expression profile in breast cancer cell lines using RNA sequencing 2.46
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 2.43
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes 2.4
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes (RNA-Seq) 2.4
Real-time observation of light-controlled transcription in living cells 2.33
Transcriptomics profiles of patient-matched normal kidney and ccRCC pairs 2.31
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 2.31
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 2.3
RNA sequencing of CACO-2 cells incubated with bifidobacteria grown on human milk oligosaccharides. 2.24
ENCODE Cold Spring Harbor Labs Long RNA-seq 2.21
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 2.19
Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria 2.19
SREBP1 drives Keratin 80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer 2.18
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription 2.12
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription [RNA-Seq] 2.12
m6A-dependent regulation of messenger RNA stability 2.1
Patient Derived Xenograft for Delivery of Precision Medicine in Castrate Resistant Prostate Cancer 2.09
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma 2.09
Short and long-term effects of CDK4/6 inhibition on early stage breast cancer 2.04
An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis 1.97
Persistence of stem cell metabolism in cancers as a failure of differentiation 1.97
Copper Regulation of HIF-1 Transcription Activity 1.96
Copper Regulation of HIF-1 Transcription Activity [RNA-seq] 1.96
Mutated H3 Histones Drive Human Pre-Leukemic Hematopoietic Stem Cell Expansion And Promote Leukemic Aggressiveness 1.94
RNA sequencing of CACO-2 cells incubated with Bifidobacteria breve grown on human milk oligosaccharides. 1.91
JAK dependent survival of ALK- ALCL 1.89
SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia [RNA-seq] 1.81
Gene expression analysis upon mtDNA depletion [RNA-seq] 1.74
Gene expression analysis upon mtDNA depletion 1.74
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 1.74
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (human cell lines RNA-Seq) 1.71
Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders 1.7
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 1.65
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 1.65
Global loss of epigenetic and transcriptional fidility defines a subclass of cancer with immunotherapy resistance 1.64
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 1.63
RNA seq with AML (NB4) cells upon FTO inhibition 1.62
Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis 1.61
The DNA methylation landscape of human melanoma [RNA-Seq] 1.5
The DNA methylation landscape of human melanoma 1.5
Patient-derived xenograft platform for metastatic melanoma: a model for studying resistance to targeted therapy. 1.5
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 1.5
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 1.5
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 1.42
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 1.41
Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome 1.4
CHD1 regulates cell fate determination by activation of differentiation-induced genes 1.38
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 1.36
Genome wide impact of loss of mechanoluminal stimulation on neonatal intestine 1.36
Identification of long noncoding RNAs in T-ALL cell lines 1.35
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma [RNA-seq] 1.32
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma 1.32
A histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing 1.31
Profiling gene expression changes in ovarian cancer cells seeded on 3D organotypic culture of omentum 1.29
Function and hormonal regulation of GATA3 in human first trimester placentation 1.25
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 1.25
Identification of long noncoding RNAs regulated by p53 1.21
SF3B1 Degron knockdown RNA-seq 1.14
Dual RNA-seq – High-resolution comparative Dual RNA-seq time-course 1.13
Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains 1.13
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 1.1
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer 1.1
Somatic cell fusions reveal extensive heterogeneity in basal-like breast cancer [RNA-Seq] 1.1
RNA-Seq analysis of human colorectal cancer with liver metastasis 1.06
BMS-470539 on human synovial fibroblasts 1.05
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 1.03
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 1.01
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 0.95
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 0.95
Therapy-induced hypoxia contributes to AML drug-resistance through BMX Kinase upregulation 0.94
DRB/GRO-Seq -/+ UV 0.92
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 0.85
Hypoxic regulation of gene expression in HUVEC is dominated by EPAS1 0.84
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 0.83
A Low-cost Multiplex Biomarker Assay Stratifies Colorectal Cancer Patient Samples into Clinically-relevant Subtypes: Singapore Cohort RNA-seq 0.82
A Low-cost Multiplex Biomarker Assay Stratifies Colorectal Cancer Patient Samples into Clinically-relevant Subtypes 0.82
RNA sequencing of T-ALL (COG study) 0.79
Analyses of T-ALL (COG study) 0.79
Gene expression profile of melanoma cell lines after overexpression or knockdown of KPC1 0.79
The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma [RNA-Seq Tumor] 0.77
FOXP2's impact on the primate transcriptome 0.71
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 0.71
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 0.71
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 0.7
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma 0.68
Gene expression changes due to PARP knockdown in human cells 0.63
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 0.61
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 0.59
RNA sequencing of GLO1-depleted MDA-MB-231 breast cancer cells 0.57
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 0.56
DAOY-Notch1/Notch2 knockout: transcriptome comparison 0.51
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 0.36
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 0.35
Transcriptional dependencies in diffuse intrinsic pontine glioma 0.3
RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 0.3
RNA-seq and small RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 0.3
The MEF2B Regulatory Network 0.26
The MEF2B Regulatory Network - RNA-seq data 0.26
Transcriptome of Primitive Human Hematopoietic Cells: A New Resource to Find hHSC-Specific Genes 0.26
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 0.26
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 0.24
RNAseq data from Mesenchymal stem cells treated with TCDD or 1-methyl tryptophan 0.23
Activating Transcription Factor 4 modulated TGFb-induced aggresiveness in triple negative breast cancer vis SMAD2/3/4 and mTORC2 signaling 0.23
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. 0.19
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 0.19
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 0.18
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.17
Genomic profiling of biliary tract cancer cell lines reveals molecular subtypes and actionable drug targets 0.17
Interferon receptor signaling pathways regulating PD-L1 and PD-L2 expression 0.16
A bioinformatics approach reveals novel mechanisms of the OVOL transcription factors in the regulation of epithelial-mesenchymal cell programming and cancer progression. 0.12
Unlocking the transcriptomic potential of formalin-fixed paraffin embedded clinical tissues: Comparison of gene expression profiling approaches 0.11
Unlocking the transcriptomic potential of formalin-fixed paraffin embedded clinical tissues: Comparison of gene expression profiling approaches [RNA-Seq] 0.11
UV_24h_GRO-Seq 0.11
RNAseq analysis of ruxolitinib treated breast cancers 0.1
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 0.08
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 0.08
Genome-wide maps of transcriptomic and epigenomic state in melanoma cell lines 0.03
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 0.01


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