Gene Query: PLK1

Dataset Description Geneva Score
Genome-wide transcriptional response to random aneuploidy in human cells 181.48
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 101.51
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 79.03
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 78.01
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 78.01
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 75.83
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 73.23
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 69.17
RNA-sequencing experiment: Treatment of MCF-7 breast cancer cells with the novel small molecule ZNA 69.12
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 66.66
miR941 overexpression experiment 65.75
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 63.57
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts 63.28
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 63.24
Expression level comparison under dividing and quiescent states in human primary fibroblasts 63.21
RNA-seq of shEZH2 cells 60.44
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 59.24
High-throughput RNA sequencing on circular RNA profiles of human pancreatic cancer cell lines and gemcitabine resistant pancreatic cancer cell lines. 58.94
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 58.42
Steroid Receptor Coactivator-2 Regulated Transcriptome in Human Endometrial Stromal Cells 57.51
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 56.06
Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic co-culture 55.56
scRNASeq analysis of cycling cardiomyocytes 54.8
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 54.26
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 54.26
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 53.28
The regulartory role of ZCCHC24 in splicing machinery 53.24
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 53.04
Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation 52.7
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 52.44
The Promyelocytic Leukemia Zinc Finger Dependent Transcriptome during Human Endometrial Stromal Cell Decidualization 51.31
Gene expression data from IMR90 control, IMR90 shRRM2 and shRRM2/shp16 50.87
GREB1, a novel target of Wnt signaling, promotes development of hepatoblastoma by suppressing TGFβ signaling 48.78
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 47.68
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 46.41
Transcriptome profiling identified a 3-lncRNA regulatory network in transthyretin against glucose induced hRECs dysfunction 45.91
SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 44.28
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 43.38
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 42.91
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors 42.76
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors [RNA-seq] 42.76
Suppression of the FOXM1 transcriptional program via novel small molecule inhibition 42.61
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 42.35
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 42.21
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 41.98
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 41.36
MYCi361 regulates MYC target genes 41.21
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 40.36
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 39.41
RNA-seq of human foreskin fibroblast cells lacking RB and/or p130 after doxorubicin treatment 39.28
Transcriptional profiles of normal human mature B cells 39.14
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 38.68
A549 cells and MSR-A549 cells 38.68
Measuring the effect of MYC on transcription during the DNA double-strand break response by RNA-seq of newly synthesized transcripts 38.43
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 38.16
Differential gene expression analysis between proliferating and quiescent human dermal fibroblasts 37.93
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 37.82
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 37.82
MDM2 and MDM4 are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors 37.18
G-quadruplex structures mark human regulatory chromatin 37.14
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 37.0
Genome wide transcriptome analysis of palbociclib or GSK3326595 treated A375 cells [Palbociclib_GSK_RNASeq] 36.75
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies 36.54
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 36.37
Effect of CHKA knockdown on C4-2 cell transcriptome 36.27
Response of HEK293 Freestyle cells to 36 h of culture in Zn(II)-depleted Freestyle medium 36.1
transcriptome studies of BRD4 inhibitor BDF-1253 on renal clear carcinoma 786-O cells 36.0
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance 35.57
Transcriptome analysis of ECFCs treated with GSK-343 and Panobinostat 35.55
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy 35.52
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 35.14
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 35.02
Global modulation of signaling pathways by SARM RAD140 in AR/ER+ breast cancer xenografts 34.99
microRNA-seq and RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 34.54
RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 34.54
IRF2 is a master regulator of human keratinocyte stem cell fate 33.68
IRF2 is a master regulator of human keratinocyte stem cell fate [RNA-seq] 33.68
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 33.61
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 32.27
A Unique Epigenomic Landscape Defines Human Erythropoiesis 31.93
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 31.93
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 31.8
Genome-wide analysis of ferroptosis related genes in liver cancer cells. 31.71
Wnt addiction of genetically defined cancers reversed by PORCN inhibition 31.68
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 31.67
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis[Ribosome Profiling] 31.63
Indoxyl sulfate stimulates angiogenesis by regulating reactive oxygen species production via CYP1B1 31.55
FOXD3 is a novel tumor suppressor in lung cancer 31.5
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 31.07
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways 31.02
Multiple roles for Grainyheadlike transcription factors in the establishment and maintenance of human mucociliary airway epithelium 30.96
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 30.9
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 30.81
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 30.73
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 30.46
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 30.43
Mammalian Hbs1L deficiency causes Pelota depletion and is associated with a unique phenotype 30.02
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 29.52
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 29.52
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 29.42
Overexpression and knockdown experiment for circCSNK1G3 29.33
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 29.2
Identification of global regulators of T-helper cell lineage specification 29.2
Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function 29.16
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 28.96
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq] 28.71
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation 28.71
Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma engages the ER-stress response II 28.62
Acetylation-Dependent Control of Global Poly(A) RNA Degradation by CBP/p300 and HDAC1/2 28.44
Gene expression comparison of resting human peripheral-blood NK cells and activated counterparts 28.26
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 28.19
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 28.19
The landscape of alternative splicing in aggressive prostate cancers 28.11
Paxillin regulates genomic networks in prostate cancer [LNCaP] 27.59
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 27.59
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 27.41
A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis 27.38
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 27.06
The interplay between SOX4 and SMAD3 in the context of breast cancer 27.06
Next generation sequencing of human hepatic stellate cell line, LX-2 treated with recombinant human TGF-β1, with DMSO or ML290 (5 µM) for 72h. 27.0
Transcriptomic analysis of the role of the integrin a6b4 in detached cells 26.94
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 26.92
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells 26.81
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells [RNA-seq] 26.81
RNA-sequencing in irradiated and normal A549 cells. 26.75
Transcriptome analysis of immature and matured human oocytes from patients of young and advanced maternal age 26.63
A code of mono-phosphorylation modulates the function of RB. 26.6
Transcriptional profiling of MCF7 cells treated with H3B05942, E2, or standard of care compounds 26.52
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 26.4
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 26.13
DAOY-NERT2 Notch/Hypoxia Transcriptome Analysis 26.12
Transcriptome analysis of AGS cells infected with Helicobacter pylori P12 25.94
Chromatin landscape of human visceral and subcutaneous adipocytes 25.88
Effect of mitochondria deficiency on senescence-associated gene expression 25.86
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 25.86
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 25.86
RNA sequencing (RNA-SEQ) of Human endothelial cells (HUVEC) in LFS, sFRP2OE, and WT conditioned media 25.73
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 25.51
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 25.39
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 25.29
miR-191 regulates human cell proliferation and directly targets multiple oncogenes [seq] 25.12
Genome wide miR-191 target profile determined by RIP and gene expression profiling 25.12
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 25.12
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 25.11
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 25.11
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 25.03
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 24.75
Differential analysis of HOXA1 in adult cells at isoform resolution by RNA-Seq [Illumina] 24.7
Differential analysis of gene regulation at transcript resolution by RNA-Seq 24.7
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 24.52
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 24.52
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 24.43
Differential gene expression of human melanoma cells [RNA-seq] 24.43
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 24.41
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 24.4
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion 24.38
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation 24.37
Aneuploidy triggers an immune response 24.32
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 24.25
RNA sequencing of GlyH-101-treated MCF-7 cell line 24.13
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer 24.08
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 24.08
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 24.06
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 24.06
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 23.86
EWSR1 influences alternative splicing through direct and indirect mechanisms 23.63
Adaptive chromatin remodeling in glioblastoma stem cell plasticity and drug tolerance 23.57
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 23.49
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 23.49
A sister of NANOG regulates genes expressed in pre-implantation human development 23.39
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 23.14
Transcription control by the ENL YEATS domain in acute leukemia 23.14
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 22.73
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 22.29
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 22.22
Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells 22.19
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 22.06
Molecular Mechanisms of Endothelial Hyperpermeability 21.79
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 21.77
A comparison of gene expression between lesional and non-lesional derived keratinocytes of Hailey-Hailey disease patients. 21.66
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 21.64
Genome-wide transcriptome profiling of NEDD9-regulated genes using RNA-seq 21.63
Genome-wide analysis of Dengue virus 2 infected cells 21.54
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 21.42
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 21.42
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 21.33
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 21.33
RNA-seq analysis to identify the genes regulated by p53-SET interplay 21.31
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 21.24
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 21.07
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 21.07
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation 21.01
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Human_RWPE1_RNA-Seq) 21.01
Single-nucleotide-resolution mapping of HBV promoters using CAGE 20.65
Differentially expressed vascular development genes for iPSC-ECs from CDI 20.64
Estrogen response in breast cancer cell line MCF-7 is dependent on NR2F2 [RNA-seq] 20.42
NR2F2 study 20.42
Gene expression by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1.4 knock-down and multiple H1 variants 20.41
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites (RNA-seq) 20.31
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites 20.31
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 20.17
Integrated Systems Biology Analysis of KSHV Latent Infection Reveals Viral Induction and Reliance on Peroxisome Mediated Lipid Metabolism 20.02
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 19.98
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 19.87
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 19.87
Expression profile of LNCaP/AR cells with or without HNF4G expression grown for long term in charcoal stripped-serum (CSS) media 19.85
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 19.54
Targeting EZH2 in MYCN-amplified Neuroblastoma [RNA-seq] 19.49
Targeting EZH2 in MYCN-amplified Neuroblastoma 19.49
Gene target specificity of the Super Elongation Complex (SEC) family: How HIV-1 Tat employs selected SEC members to activate viral transcription 19.45
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 19.43
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 19.35
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 19.28
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 19.19
Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing 19.17
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 19.04
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 19.04
Evolving Spindlin1 Small Molecule Inhibitors Using Protein Microarrays 18.97
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 18.84
Effect of Influenza virus infection on lncRNA expression in A549 cells 18.8
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 18.73
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 18.73
mRNA sequencing identifies differential gene expresssion profiles between ASCC3 knock-down cells and control cells 18.71
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 18.69
Maturation of human iNSCs 18.65
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 18.54
Endothelial gene expression analysis 18.52
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 18.52
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 18.5
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 18.5
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 18.48
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 18.48
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 18.45
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 18.45
RNA-seq in SUNE-1 cells after downregulation of DANCR expression 18.36
Aneuploidy-induced cellular stresses limit autophagic degradation. 18.31
Identification of differential expressed genes of JQ1 or JQ1+Bortezomib in colorectal cancer cells 18.12
Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx 18.03
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 18.02
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 17.96
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 17.95
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions 17.88
Global Bidirectional Transcription of the Epstein-Barr Virus Genome During Reactivation 17.77
ChIPseq and RNAseq analysis of T47D cells with/without silencing TRPS1/CHD4 17.76
CSL RNA-Seq on HKC and SCC cell lines 17.71
CSL 17.71
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 17.7
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 17.64
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 17.61
Transcriptome Analysis and Functional Identification of Adipose-Derived Mesenchymal Stem Cells in Secondary Lymphedema 17.51
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 17.49
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 17.48
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 17.36
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 17.32
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 17.32
Transcriptional responses of human insulinoma cells to acute cytokine exposure 17.31
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data 17.31
MYOD Gene Expression Regulation during Myogenic Conversion of Fibroblasts 17.3
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes. 17.13
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq] 17.13
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 17.07
RNA-Seq profiling of day 7 and day 18 kidney organoids differentiated in two batches 17.03
Lung Cancer Cell-Mediated Skeletal Muscle Mitochondrial Dysfunction is Mitigated by 1a,25-Dihydroxyvitamin D3 17.03
Analysis by Whole Transcriptome Sequencing of the Effects of LLC1 conditioned medium, LLC1 conditioned plus Calcitriol, non-conditioned medium, and non-conditioned medium plus Calcitriol on mRNA Expression in Primary Human Skeletal Muscle Cells 17.03
3’READS+, a sensitive and accurate method for 3’ end sequencing of polyadenylated RNA 16.85
Transcriptional profiling of LS1034 cells treated with tepoxalin 16.84
Effect of from Human Umbilical Vein Endothelial Cells 16.8
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 16.7
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 16.7
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 16.66
Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed 16.62
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 16.51
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 16.41
Genome-wide chromatin analysis of Ewing sarcoma 16.38
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 16.38
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 16.32
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 16.32
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 16.3
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 [RNA-seq] 16.3
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 16.29
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 16.28
Transcriptional profile of human STAT1-/- fibroblasts expressing LY6E or empty control vector 16.24
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 16.23
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 16.18
Induced DNA demethylation, genome instability and transcription 16.09
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 16.09
Proliferation pause as an early blockade of human cellular reprogramming toward pluripotency [RNA-seq analysis] 16.06
RNAseq to determine gene expression changes following depletion of SETDB1 in THP-1 AML Cells 16.05
Epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 15.93
Gene expression profiling study by RNA-seq for identifying genes associated with epithelial-mesenchymal transition and acquired resistance to ALK inhibitors 15.93
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 15.86
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 15.84
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 15.83
Whole-transcriptome profilings between a pair of HCA7-derived KRAS-wildtype cetuximab sensitive and resistant colon cancer cells from 3D culture 15.83
MCF10A H-Ras RNA-Seq 15.67
mRNA differential expression analysis in a human ex vivo model of chronic wounds 15.54
Paxillin regulates genomic networks in prostate cancer [PC3] 15.53
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 15.36
Dynamic 3D chromosomal landscapes in acute leukemia [RNA-Seq] 15.15
Dynamic 3D chromosomal landscapes in acute leukemia 15.15
Vitamin C–dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition 15.14
Vitamin C dependent KDM6 demethylation specifies a functional chromatin state for endothelial-to-hematopoietic transition [RNA-Seq] 15.14
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 15.1
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 15.1
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 15.09
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 15.09
CD97 is a Critical Regulator of Acute Myeloid Leukemia Stem Cell Function 15.05
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 15.02
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 15.01
TAF1 is critical for AE driven leukemogenesis [RNA-seq] 14.97
TAF1 is critical for AE driven leukemogenesis 14.97
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 14.93
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 14.88
PSEN1ΔE9, APPswe and APOE4 confer disparate phenotypes in human iPSC-derived microglia 14.85
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 14.83
Rescue of Fragile X syndrome by DNA methylation editing of the FMR1 14.82
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [RNA-seq] 14.82
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 14.58
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 14.55
Gene expression profiles of primary human NK cells before and after expansion on CSTX002 feeder cells, with and without IL-21 stimulation 14.54
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 14.27
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 14.17
Derivation and differentiation of haploid human embryonic stem cells 14.11
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA) 14.03
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 13.93
Effect of FGF13 depletion on the H460 cell line 13.85
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq knock-down] 13.82
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 13.81
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 13.77
Neurofibromin is an Estrogen Receptor alpha Transcriptional Co-repressor in Breast cancer 13.74
yylncT acts as a gatekeeper of the mesodermal transcriptional program by local modulation of DNMT3B [human_2] 13.73
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 13.62
Transcriptomic analysis of senescent cells upon EXOC7 knockdown. 13.47
A map of gene expression in neutrophil-like cell lines 13.38
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 13.37
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 13.37
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity 13.14
Iron response of HepG2 cells 13.12
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 13.05
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1 12.95
FOXP2's impact on the primate transcriptome 12.92
RNA seq with AML (NB4) cells upon FTO inhibition 12.62
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 12.57
High-efficiency RNA-based reprogramming of human primary fibroblasts 12.5
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 12.46
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 12.46
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 12.42
Apatinib preferentially inhibits Gefitinib-resistant lung cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway 12.4
Bone marrow derived human B cells [normal proB] 12.38
Transcriptomic insights into human decidual and peripheral blood CD8 T cells 12.37
Selective expression of long non-coding RNAs in a breast cancer cell progression model 12.17
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells 12.12
X-Ray induced DNA-Hydroxymethylation changes 12.02
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 12.01
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 11.66
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer (RNA-Seq) 11.62
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer 11.62
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 11.56
Differential gene expression in Jagged1 treated human dental pulp cells. 11.48
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 11.41
RNA-sequencing analysis of glucose and acetate regulated transcripts in glioblastoma cells 11.36
Identification of differentially expressed genes between senescence and senescence bypass cells 11.3
High throughput analysis of three human adipose cell lines PAZ6, SGBS and SW872 11.23
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation 11.15
Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation (RNA-seq) 11.15
Identification of HOXB13 target genes responsive to BET inhibitors 11.11
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 11.01
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 11.0
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis 10.79
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis: Expression data (RNA-seq) 10.79
CRISPR-Cas9 based screen for p53-bound enhancers that function in oncogene-induced senescence 10.79
Gene expression profile of multiple myeloma cell lines treated with CB-5083 10.59
The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing [RNA-seq] 10.53
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 10.38
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition 10.37
MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block 10.37
The Genetic Landscape of Diamond-Blackfan Anemia 10.29
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 10.14
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 10.14
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer 10.04
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 9.98
hiPSCs unravel aberrant TGFβ signaling as an etiology of left ventricular non-compaction 9.82
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 9.82
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 9.8
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 9.8
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 9.72
ARID1A and ARID1B loss in HCT116 cells 9.71
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 9.64
RNA sequencing of human mammary epithelial cells 9.39
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 9.33
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer [RNA-Seq] 9.28
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 9.19
Generation of KRAS signatures using immortalized isogenic lung cells. 9.16
Global gene expression differences between blood- and lymphatic-specific human dermal microvascular endothelial cells 9.09
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 9.09
RNA-seq of tumor cells following angiopellosis extravasation 9.08
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 9.06
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 9.04
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 [RNA-seq] 9.04
Allogeneic mature human dendritic cells generate superior alloreactive regulatory T cells in the presence of IL-15 8.96
Conservative alteration of chromosomal expression pattern across human solid tumor types 8.83
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes 8.81
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes [seq] 8.81
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 8.49
An integrative analysis of non-coding regulatory DNA variations associated with autism 8.47
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 8.44
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 8.23
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 8.07
Searching for target genes of miR-508/509/506/514 in HCT116 cells 7.89
Ro60-knockout cells 7.59
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 7.51
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth [RNA-Seq] 7.44
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth 7.44
Characterization of parental and rociletinib-resistant derived H1975 cell lines 7.42
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 7.34
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 7.3
Immune Checkpoint Regulation of Pulmonary Fibrosis [bulk RNA-seq] 7.16
RNA-seq of hiPSCs-derived NPCs from 3 pairs of dizygotic discordant twins for Congenital Zika syndrome 6.99
Study of dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest 6.91
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs 6.59
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 6.49
Splicing and gene expression changes in human mammary epithelial MCF-10A cells expressing SR or SR-like proteins 6.47
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 6.26
Global gene expression differences between blood- and lymphatic-specific endothelial colony forming cells 6.03
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 5.98
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 5.83
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 5.76
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 5.76
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 5.72
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 5.33
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 5.33
Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis 5.31
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 5.28
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 5.13
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 5.04
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 4.93
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 4.77
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 4.65
Rapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq) 4.44
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 4.32
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 4.04
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 4.04
RNA-seq profile of expanded human ST2-transduced Tregs cultured with IL-2 and TCR in the presence or absence of IL-33 4.03
Non-synchronized cell cycle transcriptomics in U2OS and HeLa cancer cells 3.81
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  3.73
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 3.67
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 3.67
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 3.55
Expression profiling of converted and control dermal BJ fibroblasts 3.53
p63 establishes epithelial enhancers de novo at critical craniofacial development genes 3.53
Gene expression profile of CRC-derived HILEC 3.47
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 3.17
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 3.17
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue 3.17
Genome-wide maps of transcriptomic and epigenomic state in melanoma cell lines 3.08
RNA-seq analysis upon ARID1B overexpression 3.07
The impact of oil spill to lung health – insights from an RNA-seq study of human airway epithelial cells 2.95
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 2.9
CD133hi, Notchhi, DP (double positive) and DN (double negative) in GBML8 and GBML20, both patient-derived glioblastoma tumorsphere cultures 2.88
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 2.8
RNA-seq of human foreskin fibroblast cells lacking RB, p130, and p107 treated with doxorubicin. 2.73
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 2.72
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 2.71
6mer seed toxicity in viral microRNAs 2.65
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 2.59
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 2.59
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 2.59
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 2.5
Comparative analysis of mesenchymal stem cells derived from amniotic membrane, umbilical cord and chorionic plate under serum-free condition 2.45
Transcriptome profiling of de-differentiated chondrocytes over-expressing miR-138 or miR-181ab1 during osteogenic induction 2.41
β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells 2.15
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 2.08
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 2.01
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 2.0
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 1.98
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 1.98
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 1.98
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 1.78
ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression 1.65
System-wide profiling of RNA-binding proteins uncovers key regulators of virus infection 1.64
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 1.48
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 1.33
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 1.31
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 1.31
Antioxidant metabolism in activated CD8+ T cells regulates stem-like human memory T cell formation and anti-tumor immunity 1.28
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 1.19
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 0.79
Metabolism as an early predictor of DPSCs aging 0.71
High-resolution comparative analysis of great ape genomes 0.67
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  0.66
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 0.6
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 0.6
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 0.53
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 0.36
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 0.25
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 0.25
The circadian transcriptional landscape in primary human mammary epithelial cells 0.2
Effect of TUNAR silencing and GSK3 inhibition on human b-cell transcriptome 0.15
Knockout of miR-221 and miR-222 reveals overlapping and specific function between paralogous miRNAs 0.14
Concomitant BCORL1 and BRAF mutations in vemurafenib-resistant melanoma cells 0.13


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