Gene Query: PLXDC2

Dataset Description Geneva Score
Effect of Hotair overexpression in human breast cancer cell lines 104.67
Effect of hypoxia and TGFβ1 on gene expression in HPF fibroblast cells 95.14
Differential gene expressions in the heart of hypertrophic cardiomyopathy patients 79.98
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor 69.39
ZIKV infection of monocytes activates inflammasome pathways 67.3
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 63.74
STVI-120 Induction of differentiation in human epidermal stem cells followed by differential splicing analysis 57.82
Expression profile of LNCaP/AR cells with or without HNF4G expression grown for long term in charcoal stripped-serum (CSS) media 56.19
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 52.46
Genome-wide analysis of herpes simplex virus type 1 (HSV-1) infected cells 49.22
Self-organization of polarized cerebellar plate neuroepithelium in three-dimensional culture of human pluripotent stem cells 46.1
RNA-seq of young and quiescent MRC-5 human fibroblasts 45.39
RNA expression following TMPRSS11B overexpression or depletion 41.57
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia 41.29
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia (RNA-seq) 41.29
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 38.42
Bi-allelic Alteration and Dysregulation of the Hippo Pathway in Mucinous Tubular and Spindle Cell Carcinoma of the Kidney 38.17
RNA-seq in untreated and flagellin-treated Human Intestinal Myofibroblast cells (HIMF) 37.98
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 37.34
Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures 37.24
CD1c+ dendritic cell activation by Plasmodium falciparum-infected red blood cells 36.46
Mutation independent activation of the Notch pathway is associated with Lapatinib resistance in Her2+ breast cancer cell lines 35.65
CircRNAome diversity in human mature B-cells, T-cells and monocytes 34.37
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 34.02
Mycobacterium bovis Bacillus Calmette-Guerin (BCG) reprograms melanoma microenvironment to promote antitumor T cell responses 33.48
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression 33.3
microRNA suppresses prostate cancer stem cells and metastasis by inhibiting a cohort of pro-metastasis targets including CD44, Rho GTPases and EZH2 33.11
Mutated H3 Histones Drive Human Pre-Leukemic Hematopoietic Stem Cell Expansion And Promote Leukemic Aggressiveness 31.62
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II 31.22
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 30.7
Functional studies of missense TREM2 mutations in human stem cell-derived microglia 30.37
Catalogue of differentially expressed long non-coding RNAs following activation of human and mouse innate immunity 30.34
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 30.3
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 30.3
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 30.12
Integration of genome-wide DNA methylome and transcriptome of human intestinal fibroblasts reveals novel candidate gene signatures in Crohn’s disease-associated fibrosis 30.02
Human iPSC derived glomeruli facilitate accurate modelling of podocytopathy 28.98
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 28.72
A549 cells and MSR-A549 cells 28.72
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 28.13
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 27.77
Inhibition of the Aryl Hydrocarbon Receptor - Polyamine Biosynthesis Axis Suppresses Multiple Myeloma and prostate cancer progression 27.65
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation 27.35
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq] 27.35
Effects of rFVIIIFc on human macrophages 27.27
Prostaglandin E2 inhibits pro-fibrotic function of human pulmonary fibroblasts by disrupting Ca2+-signaling 27.13
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 26.56
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability 26.19
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability [ RNA-seq] 26.19
RNA sequencing to compare gene expession in control and PF228-treated hepatic stellate cells 25.97
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) 25.97
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 25.94
Next Generation Sequencing Facilitates Quantitative Analysis of ALDH+ E-BCSC, CD24-CD44+ M-BCSC and Bulk tumor cell Transcriptomes from MC1 and Vari068 PDX models of TNBC 25.75
RNA-seq profiling identifies Androgen Receptor-regulated genes in prostate cancer cells 25.6
Androgen Receptor-regulated genes in prostate cancer cells 25.6
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 25.49
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 25.07
Effect of selective glucocorticoid receptor modulation (SGRM) on gene expression in human prostate cancer cell lines 24.53
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA_seq_Whole] 24.12
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [RNA-seq] 23.55
Identification of the networks that regulate human monocytic myeloid-derived suppressor cell differentiation into inflammatory macrophages 23.54
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 23.51
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq] 23.51
Estrogen receptor and mTOR signaling rewires cancer metabolism in obesity-associated breast cancer 23.48
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis 23.39
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis: Expression data (RNA-seq) 23.39
RNA-sequencing WT vs SOCS3 knockout Glioblastoma stem-cells 23.12
Transcriptome analysis of Zika infected neural stem cells 23.11
Zika infected neural stem cells 23.11
Histone H3 Lysine4 Acetylation-Methylation Dynamics Define Breast Cancer Subtypes 23.07
Histone H3 lysine 4 acetylation-methylation dynamics define breast cancer subtypes [RNA-seq] 23.07
EZH2 inhibitor-mediated transcriptional profiling in prostate cancer cells [RNA-seq] 22.56
Distinct changes in transcriptional profiles and epigenetic patterns mediated by EZH2 inhibitors in sensitive and insensitive prostate cancer cells 22.56
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 22.25
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 22.1
RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells I 21.53
RNA-seq identifies novel lncRNAs involved in vascular smooth muscle cell proliferation 21.5
Comparative analysis of mesenchymal stem cells derived from amniotic membrane, umbilical cord and chorionic plate under serum-free condition 21.39
A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo 21.39
RNA-Seq profiling of day 7 and day 18 kidney organoids differentiated in two batches 21.36
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 21.18
RNAseq to determine gene expression changes following depletion of SETDB1 in THP-1 AML Cells 21.11
The dynamic landscape of coding and non-coding RNAs in the innate immune response to microbial pathogens 20.93
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 20.91
The effect of Foxc1 deficiency on undifferentiated and differentiated human primary keratinocytes 20.61
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 20.37
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 20.37
AQP5-Expressing Cells Serve as Stem Cells and Cancer Origins in the Distal Stomach 20.33
Selective expression of long non-coding RNAs in a breast cancer cell progression model 20.11
Neutrophils in systemic onset Juvenile Idiopathic Arthritis display sepsis-like features which can be reverted by IL-1 blockade 20.11
Next Generation Sequencing Facilitates Quantitative Analysis of Human Pluripotent Stem Cell-Derived Endocardial-like And Primary Cardiac Endothelial Cell Transcriptomes 20.07
Transcription control by the ENL YEATS domain in acute leukemia 19.99
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 19.99
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 19.95
Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols 19.56
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 19.51
Therapy-induced hypoxia contributes to AML drug-resistance through BMX Kinase upregulation 19.45
Role for the Transcriptional Activator ZRF1 in Breast Cancer Progression and Endocrine Resistance 19.26
Characterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer 18.73
Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2 18.67
ARID1A is a critical regulator of luminal identity and therapeutic response in oestrogen receptor-positive breast cancer (RNA-Seq) 18.61
Intron retention induced by microsatellite expansions as a disease biomarker. 18.41
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 18.36
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 18.36
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis [bulk RNA-Seq] 18.32
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis 18.32
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 18.26
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 18.26
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L 18.2
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 18.19
Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes 18.1
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [ribosome profiling] 18.06
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with pancreatic carcinoma 17.96
Transcriptomic profiling of mesenchymal stem cells (MSC) differentiation into mesangial cells 17.89
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages (RNA-Seq, CAGE and ChIP-Seq) 17.82
Utilizing single-cell variations to reveal environment-dependent tuning of network connectivity in human macrophages 17.82
RNA splicing alteration on glioblastoma and normal neural stem cells 17.8
Expression data from human perivascular stem cell-derived extracellular vesicles (PSC-EVs) and PSCs 17.73
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 17.62
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 17.62
PTHrP overexpression in MCF7 cells 17.59
RNAseq to determine whether bidirectional transcription occurs over transposable elements following depletion of SETDB1 in THP-1 AML Cells 17.57
Trans-chromosomal regulation by a novel lincRNA required for adipogenesis that escapes X-chromosome inactivation 17.56
Gene expression alterations of pancreatic intraepithlial neoplasia 17.38
Differential gene expression in Jagged1 treated human dental pulp cells. 17.33
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 17.31
Effect of SHP2 inhibition on hepatic stellate cell transcriptome. 17.15
Identification of an IL-1-induced gene expression pattern in AR+ PCa cells that mimics the molecular phenotype of AR- PCa cells 16.95
Enriched EWSR1 and EWS-FLI1 RNA-seq of HNRNPH1-silenced TC32 Ewing sarcoma and 293T human embryonic kidney cells. 16.91
RNA-Sequencing shows novel transcriptomic signatures in failing and non-failing human heart 16.87
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell type specificity 16.78
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 16.76
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival 16.61
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival [RNA-Seq] 16.61
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor [human RNA-seq] 16.28
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor. 16.28
RNA Sequencing of three pairs of gastric cancer 16.27
Expression profiles of the four human major ectodermal lineages 16.22
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 16.22
Transcriptional profiles of human blood dendritic cell (DC) subsets at steady state 16.21
Allelic expression mapping across cell lineages reveal repressor disruption among disease SNPs 16.05
RNA sequencing of primary human platelets and in vitro cell lines 16.04
Reducing the structure bias of RNA-Seq reveals a large number of non-annotated non-coding RNA 15.94
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (wtRNA-Seq) 15.85
Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx 15.55
Single-Cell Genotyping of Transcriptomes 15.53
RNA-seq of Single-Cell Genotyping of Transcriptomes 15.53
Next Generation Sequencing Study of Circadian Changes in Transcriptome of Human Pineal Gland 15.5
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells 15.47
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells [RNA-Seq] 15.47
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 15.37
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 15.37
Definition of Natural Killer cell heterogeneity in humans and mice by high-throughput single-cell RNA sequencing 15.35
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 15.28
RNA-sequencing of fibrolamellar carcinoma (FLC) cell line treated with miR-375 mimic 15.26
MLL-AF4 binds directly to a BCL-2 specific enhancer and impacts H3K27 acetylation 15.16
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 15.09
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 15.09
Transcriptome Analysis and Functional Identification of Adipose-Derived Mesenchymal Stem Cells in Secondary Lymphedema 15.01
RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells. 15.0
The influence of PPFIA1 silencing to gene expression in breast carcinoma cell line and head and neck squamous cell carcinoma cell lines by RNA-sequencing in three dimensional collagen I 14.88
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 14.86
Transcriptional landscape of epithelial and immune cell populations revealed through FACS-seq of healthy human skin 14.77
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 14.68
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 14.68
RNA-seq expression data from EB-HSPC after AM580 treatment compated to DMSO-trated and FL-HSPCs 14.59
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization 14.52
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization [RNA-Seq] 14.52
RNA sequencing analysis of human embryonic stem cells and axial progenitors 14.41
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (mRNA-Seq) 14.39
Transcriptional changes after overexpression of proliferation drivers in human mammary epithelial cells. 14.38
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 14.2
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 14.2
The role of antigen presenting cells in the induction of HIV-1 latency in resting CD4+ T-cells 14.12
An in vitro human liver model by iPSC-derived parenchymal and non-parenchymal cells 14.07
Generation of trichogenic adipose-derived stem cells by expression of three factors 14.03
Interferon-γ Converts Human Microvascular Pericytes into Negative Regulators of Alloimmunity through Induction of Indoleamine 2,3-Dioxygenase 1 13.99
Human iPSC-derived glomeruli provide an advanced model to interrogate podocyte biology and accurately recapitulate podocytopathy 13.93
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 13.76
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 13.75
Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues 13.69
Human primary macrophages derived in vitro from circulating monocytes comprise adherent and non-adherent subsets with differential expression of Siglec-1 and CD4 and permissiveness to HIV-1 infection 13.62
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 13.61
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 13.61
RNA-sequencing transcriptome profiling of normal human keratinocytes differentiation 13.59
Next-generation RNA sequencing to determine changes in gene expression during breast cancer progression 13.51
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes 13.33
Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation 13.29
Generation of Patient-Matched Malignant and Normal Primary Cell Cultures from Clear Cell Renal Cell Carcinoma Patients 13.23
Hydroxychloroquine inhibits responses to group A streptococcus in peripheral blood mononuclear cells 13.2
Global transcriptome analysis of HAP1 cells 13.19
p63 controls the enhancer landscape during keratinocyte differentiation 13.08
The DNM3OS lncRNA is a reservoir of fibromiRs with major functions in fibroblast response to TGF-beta and fibrogenesis 13.04
RNA-Seq analysis of human lung fibroblasts exposed to TGF-β 13.04
Differential gene expression of static and intermittent compressive force treated human periodontal ligament cells 13.0
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 12.89
DNA Methylation Reprograms Metabolic Gene Expression in End-Stage Human Heart Failure 12.86
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 12.84
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 12.81
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance 12.78
A Novel Population of Human Cardiac Resident Mesenchymal Stem Cells 12.76
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence 12.69
Codon usage optimization in pluripotent embryonic stem cells [RNA-seq] 12.65
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells 12.61
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 12.56
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 12.5
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 12.42
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis 12.38
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [RNA-Seq_Hs] 12.38
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 12.28
Transcriptome profiling of a mouse model of alveolar soft part sarcoma 12.25
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 12.23
Next Generation Sequencing Facilitates Quantitative Analysis of UVB(20mJ/cm2 and 40mJ/cm2) exposed and untreated HaCaT keratinocytes Transcriptomes 12.16
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing (Total RNA sequencing) 12.08
Whole transcriptome analysis of PBMCs stimulated with either a P. aeruginosa phage PNM lysate or with its bacterial host P. aeruginosa 12.05
Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing 11.96
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 11.94
RNA expression profiling of human mPB or CB-derived CD34+ cells treated with UM171 at different doses 11.92
Dual modulation of neuron specific microRNAs and the REST complex promotes functional maturation of induced human adult neurons 11.76
Progesterone Receptor- and FOXO1-dependent transcriptomes decidualized human endometrial stromal cells 11.66
Progesterone receptor transcriptome and cistrome in decidualized human endometrial stromal cells 11.66
FOXO1 is required for binding of PR on IRF4, novel transcriptional regulator of endometrial stromal decidualization 11.66
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 11.63
NAPRT activation of macrophages 11.59
Morphological and molecular characterization of human dermal lymphatic collectors 11.55
Improved genome-wide mapping of uncapped and cleaved transcripts in eukaryotes—GMUCT 2.0 11.51
Transcriptomes of human monocytes after ex vivo exposure to uric acid 11.41
Long-term expandable SOX9+ chondrogenic ectomesenchymal cells from human pluripotent stem cells 11.38
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 11.29
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 11.23
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 11.23
Transcriptome profiling of influenza virus-infected human bronchial epithelial cells 11.07
Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with Eralpha 11.06
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 11.01
AR-independent prostate cancer is sustained through FGF signaling 11.01
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 10.96
Differential expression of long non‑coding RNA and mRNA in children with Henoch‑Schönlein purpura nephritis 10.91
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas 10.84
PR isoform-specific ER and PR chromatin binding and gene expression observed in-vitro in breast cancer cells. 10.78
Comprehensive RNA sequencing of healthy human endometrium at two time points of the menstrual cycle 10.69
IL-6/Stat3-Dependent Induction of Distinct, Obesity-Associated Natural Killer Cells Deteriorates Energy and Glucose Homeostasis 10.61
RNA-seq of cancer-associated fibroblasts (CAF) treated with PBS or extracellular vesicles (EV) from MCF10A or MDA-MB-231 cells 10.57
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 10.54
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes 10.49
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes [RNA-seq] 10.49
Salmonella activation of STAT3 signaling by SarA effector promotes intracellular replication and production of IL-10 10.47
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 10.45
Proteolytic cleavage by taspase1 and the regulation of the stability of MLL1 10.44
Non-coding regions are the main source of tumor-specific antigens 10.41
Non-coding regions are the main source of tumor-specific antigens [human] 10.41
EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling 10.41
RNAseq of IL-36 stimulated primary human keratinocytes 10.39
Human Airway Smooth Muscle Transcriptome Changes in Response to Asthma Medications 10.37
Genome-wide identification of cancer-specific alternative splicing in circRNA 10.35
Suppression of NAF-1 in Breast Cancer Cells Reduces their Tumorigenicity by Interfering with Cellular Iron Distribution and Metabolism and Ensuing ROS Formation and Apoptosis 10.25
Transcriptomic Analysis of Endothelial Cells from Fibrovascular Membranes in Proliferative Diabetic Retinopathy 10.25
Reprogrammed myeloid cell transcriptomes in NSCLC 10.24
Expression data for hiPSC-derived RPE treated with 10mM Nicotinamide or vehicle 10.23
Toxoplasma gondii infection of human retinal pigment epithelial cells 10.21
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 10.15
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 10.14
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 10.14
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 10.06
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 10.02
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 9.99
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 9.96
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 9.95
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 9.93
Investigation about fibroblasts of different origins in culture 9.92
The transcriptome of human endometrial mesenchymal stem cells under TGFβR inhibition reveals improved potential for cell-based therapies 9.83
The contribution of adenosine receptor 3-mediated signaling to TLR4-induced responses by human dendritic cells 9.82
Genome-wide expression profiling of an in vitro model for studying esophageal epithelial differentiation 9.82
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression [RNA-Seq] 9.79
Prediction of bacterial infection outcome using single cell RNA-seq analysis of human immune cells [sorted population Bulk RNA-seq] 9.74
Single-Cell Transcriptome Analysis of Lineage Diversity and Microenvironment in High-Grade Glioma 9.72
Fibroblasts in cholesteatoma activate osteoclasts. 9.72
LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs 9.6
Generation and functional characterization of MDSC-like cells 9.52
Zika virus antagonizes interferon response in patients and disrupts RIG-I-MAVS interaction through its CARD-TM domains 9.41
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 9.1
Transcriptome Analysis of PBMCs in peripheral blood of patients with hepatocellular carcinoma 9.08
Anaylsis of the effect of down-regulation of the EWS-FLI1 fusion protein in Ewing Sarcoma cells by RNA-seq. 8.99
Tyrosine Kinase Inhibitor Cardiotoxicity 8.94
High-Throughput Screening of Human Induced Pluripotent Stem Cell Cardiomyocytes Predicts Tyrosine Kinase Inhibitor Cardiotoxicity 8.94
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells 8.84
Human serum and heparin-free platelet lysate as appropriate xeno-free alternatives for production of human MuStem cell batches 8.78
RNA sequencing of erythroid and granulomonocytic colonies differentiated from transduced bone marrow CD34+ cells expressing U2AF1 S34F mutation, U2AF1 wild-type or empty vector control 8.73
Long noncoding RNA LNMAT1 promotes lymphatic metastasis in bladder cancer 8.73
An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans. 8.64
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines [RNA-Seq] 8.57
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines 8.57
Reprogramming of Endothelium Into Hematopoietic Progenitors by Defined Factors and Vascular Induction 8.46
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 8.45
Transcriptional profile in human S. haematobium infection 8.4
Pain-driven transcriptome changes in synovium of knee osteoarthritis patients 8.37
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 8.27
Next Generation Sequencing Facilitates Quantitative Analysis of Human Primary and Pluripotent Stem Cell-Derived Epicardial Cell Transcriptomes 8.26
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. 8.26
Gene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4 8.18
Expression profiling of ILC transitional populations and Aiolos accessability and H3K27ac histone modifications in transfected MNK3 cells 8.15
RNA-Seq from human ILC transitional populations 8.15
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 8.13
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 8.12
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 8.08
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 8.08
miCLIP, RNA-Seq, and Ribo-Seq in MOLM13 cells 7.94
Effects of a nutritional supplement in older individuals subject to ten days of complete bed rest. 7.93
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 7.87
Gene expression profiles of tumor-infiltrating CD8 T cells in hepatocellular carcinoma 7.75
circNFIB suppresses lymphatic metastasis of pancreatic cancer 7.71
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy 7.68
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells 7.63
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells [RNA-Seq] 7.63
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype 7.55
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype [RNA-seq] 7.55
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 7.53
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq knock-down] 7.52
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 7.47
The transcriptome of Kawasaki Disease arteritis 7.37
RNA-Seq in neutrophils from Antiphospholipid Syndrome 7.36
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 7.34
Truncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line 7.28
Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype 7.23
The Promyelocytic Leukemia Zinc Finger Dependent Transcriptome during Human Endometrial Stromal Cell Decidualization 7.17
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice 7.16
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription 7.15
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription [RNA-Seq] 7.15
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 7.15
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells 7.02
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 6.86
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] 6.86
Novel Atherogenic Pathways from the Differential Transcriptiome Analysis of Diabetic Epicardial Adipose Tissue 6.81
A map of gene expression in neutrophil-like cell lines 6.8
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 6.73
Respecifying human iPSC-derived blood cells into highly engraftable hematopoietic stem and progenitor cells with a single factor 6.72
Immune Checkpoint Regulation of Pulmonary Fibrosis [bulk RNA-seq] 6.69
C9/ALS Human Embryonic Stem Cells and C9/ALS Induced Pluripotent Stem Cells 6.65
TLR2 dimerization blockade allows generation of homeostatic intestinal macrophages under acute colitis challenge 6.62
Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant 6.58
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies [RNA-Seq] 6.53
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies 6.53
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors 6.32
Tpl-2 small molecule project 6.23
Tpl-2 and MEK small molecule inhibitors 6.23
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 6.22
Activity-dependent transcriptional changes in human neurons 6.21
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 5.96
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 5.96
Modeling Human Cancer-induced Cachexia (Human) 5.94
microRNA-seq and RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 5.9
RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 5.9
Non-transmissible measles virus vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells 5.83
Inhibition of Enhancer of Zeste Homologue 2 attenuates TGF-β dependent hepatic stellate cell activation and liver fibrosis 5.82
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 5.82
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence 5.78
Histone acetyltransferase p300 induces de novo super-enhancers to drive cellular senescence [RNA-seq] 5.78
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 5.75
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 5.75
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 1] 5.67
Expression profiling and occupancy after knockdown or over-expression of HFN1A or HNF4G in prostate cancer cells 5.66
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers 5.64
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers (RNA-Seq) 5.64
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis [RNA-seq] 5.61
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis 5.61
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 5.56
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion 5.55
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 5.53
Transcriptome of invasive mucinous adnocarcinoma of the lung and adjacent normal lung tissues from 6 patients based on RNA-seq method 5.35
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 5.3
a-synuclein accumulation in an iPSC derived model of early onset sporadic Parkinson’s Disease reveals novel drug targets 5.28
CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops 5.24
Three congruent human Schwann cell models of CMT1A reveal a converged phenotype 5.21
Multi-omic measurements of heterogeneity in HeLa cells across laboratories 5.2
Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders 5.17
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 5.16
Differentially expressed genes during pancreatic bud differentiation in cellular aggregates 5.09
TALEN-based knockout of mir-141 and mir-200c in SK-BR-3 cells 5.07
Global gene expression analysis of human monocyte-derived dendritic cells (DCs) treated with HMGN1 (N1) and R848 alone or in combination. 5.01
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 4.97
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 4.97
Characterization of Human Pegivirus Infection in Liver Transplantation Recipients 4.89
A compendium of promoter-centered long-range chromatin interactions in diverse human tissues and cell types 4.87
Whole Transcriptomic Sequencing of Metastatic Castration Resistant Prostate Cancer Samples 4.86
Urinary sediment transcriptomic and longitudinal data to investigate renal function decline in type 1 diabetes 4.85
Wnt1 silences CC/CXC motif chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma 4.74
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses 4.73
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 4.72
OBESITY IS ASSOCIATED WITH IMPAIRED EXPRESSION OF THE GLYCOSYLTRANSFERASE EOGT IN DECIDUALIZING ENDOMETRIUM 4.63
Hemogenic Endothelium transcriptome along the timeline of hESC differentiation 4.58
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 4.54
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 4.54
Xeno-free and Chemically Defined Human System for Culturing Human Epidermal Keratinocytes 4.48
Epigenomes and Transcriptomes of human monocytes from Hyper IgD Syndrome (HIDS) patients 4.37
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 4.27
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 4.16
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 4.15
Leucegene: AML sequencing (part 6) 4.15
Pericyte-like cells generated from human pluripotent stem cells support hematopoietic stem and progenitors ex vivo 4.03
lncRNA expression analysis in patients with eosinophilic and neutrophilic asthma 3.97
Next Generation Sequencing Compares Effects of microRNA-9 perturbation in control and SZ hiPSC NPCs 3.96
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 3.93
Anti-Inflammatory Effects of Budesonide in Human Fetal Lung 3.92
Cancer-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1 3.91
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 3.91
Transcriptomic profiling of mRNA and miRNA from nasopharyngeal carcinoma (NPC) and normal control samples 3.89
Transcriptomic profiling of nasopharyngeal carcinoma (NPC) and normal control samples 3.89
Ribosome profiling of TGFb-treated cells indicates reduced leucine availability 3.87
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 3.86
The gene expression profiles of gallbladder cancer 3.82
RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues 3.82
Fixed tissue ChIP-Seq (FiT-Seq) of archived clinical samples reveals chromatin dynamics and tumor-specific enhancer profiles 3.76
RNA-Seq of Kaposi’s sarcoma reveal alterations in glucose and lipid metabolism 3.76
Study functions of ADAR proteins using next generation sequencing of genome and transcriptome 3.56
RNA-seq analysis upon ARID1B overexpression 3.54
Combined Genome and Transcriptome Sequencing to Identify Allelic Selection in Epithelial Ovarian Cancer 3.49
A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells 3.43
Comparing oestrogen-responsive genes in endometrial and breast cancer cell lines 3.4
mRNA expression profile of Lymphocytes by high-throuput sequencing 3.38
Next Generation Sequencing Analysis of Colorectal Cancer Tissue Transcriptomes 3.35
Interferon-beta-inducible genes in human monocyte-derived macrophages (MDMs) 3.25
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 3.2
The transition from proliferation to quiescence in glioblastoma stem-like cells requires Ca2+ signaling and mitochondria remodeling 3.17
Select correlative genes involved in pathogenesis of idiopathic interstitial pneumonia by high-throughput sequencing analysis 3.11
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 3.1
Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability? 3.08
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [RNA-Seq] 3.06
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [DNA Methylation] 3.06
RNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation 2.92
H3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation [RNA_Chondroblastoma_H3K36M_H3WT] 2.9
H3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation 2.9
The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner 2.84
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 2.78
Long non-coding RNA profiling of human lymphoid progenitors reveals transcriptional divergence of B cell and T cell lineages 2.63
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 2.61
Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis 2.48
Transcriptomic profiling of sequential tumours from breast cancer patients provides a global view of metastatic expression changes following endocrine therapy 2.43
Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing analysis 2.43
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with colorectal carcinoma 2.41
Transcriptome analysis of peripheral blood monocytes 2.34
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 2.34
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 2.34
ERBB3 and NGFR mark distinct skeletal muscle progenitor cells in human development enabling enrichment and maturation of hPSC muscle 2.34
Genome-wide maps of chromatin state and mRNA expression patterns in leukemic cell lines 2.33
EWS-Fli and LNC regulated genes in comparison to GFP samples 2.3
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 2.22
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 2.12
Deletions in the ATAD3 gene cluster cause cerebellar developmental defects with mitochondrial DNA abnormalities owing to local cholesterol insufficiency 2.12
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 2.1
RNA-seq on Enasidenib or DMSO Treated CD71+ Cells from Umbilical Cord Blood (UCB) 1.97
The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma [RNA-Seq Tumor] 1.93
In vitro modeling of human germ cell development using pluripotent stem cells 1.93
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex (Gro-seq) 1.9
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex 1.9
Changes in CD34 and Erythroid Progenitor Transcriptome After RUNX3 Kock-down 1.71
RNAseq of Breast cancer PDX samples 1.64
The effect of slow and rapid H2S production on the levels of LPS-induced proinflammatory mediators and transcription in different human cell cultures 1.61
RNA-Seq analysis of NKX2.2 knockdown in human pancreatic islets 1.59
NKX2.2 1.59
T47D xenografts treated with various combinations of ER- and PR-targeting therapies 1.42
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 1.36
Dissecting cell composition and cell-cell interaction network of normal human heart tissue by single-cell sequencing 1.26
The Cushing's disease adipose gene expression profile reveals effects of long term glucocorticoids on adipose tissue lipid, protein and glucose metabolism 1.26
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 1.25
Illumina HiSeq Sequencing on Breast cancer PDX samples 1.19
Analysis of transcriptome changes following SOX2 knockdown in three different Ewing sarcoma cell lines 1.18
Gene Expression Signature in Adipose Tissue of Acromegaly Patients 1.12
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq] 1.12
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations 1.12
Frailty in middle age is associated with race-specific changes to the transcriptome. 1.1
RNA-sequencing of pediatric idiopathic dilated cardiomyopathy patients and healthy controls 0.99
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 0.97
The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells 0.96
Steroid Receptor Coactivator-2 Regulated Transcriptome in Human Endometrial Stromal Cells 0.9
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 0.87
ELP1 splicing correction reverses proprioceptive sensory loss in familial dysautonomia 0.77
Peripheral whole blood mRNAs and lncRNAs expression analysis in eosinophilic asthmatics 0.7
A RUNX2-mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells 0.69
Transcriptome analysis of fetal Klinefelter testis tissue samples compared to controls 0.69
Gene expression analysis of a panel of human fibroblasts that generate an aligned (anisotropic) vs non-aligned extracellular matrix 0.61
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency 0.61
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency [RNA-Seq] 0.61
mRNA sequencing of highly and lowly metastatic human colorectal cancer PDXs 0.61
Effect of hyper-and hypoactivation of Notch signaling in IL-4-stimulate THP-1 0.52
Pluripotent stem cell models of Blau syndrome reveal an IFN-<gamma>-dependent inflammatory response in macrophages 0.51
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 0.49
RNA-sequencing of highly pure synovial tissue macrophages reveals two distinct osteoarthritis subgroups that indicate different disease mechanisms. 0.45
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 0.4
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 0.4
Dilated cardiomyopathy vs Myocarditis 0.37
Expression of the mannose receptor (CD206) defines distinct populations of human colonic macrophages in health and inflammatory bowel disease 0.36
Identification of differentially expressed circRNA in gallbladder cancer compared with matched normal tissue 0.34
Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies 0.33
Genome Wide Chromatin Mapping of accessibility (ATAC-seq) and H3K27ac histone modifications in CD56bright and CD56dim natural killer cells 0.3
Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis 0.27
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration [RNA-seq2] 0.26
BMS-470539 on human synovial fibroblasts 0.23
RNA-Seq Analysis in purified iPS cell-derived neuronal samples 0.17
Cutaneous Immunoprofile of Three Spotted Fever Group Rickettsiosis 0.15
Longitudinal transcriptome profiling of post-treatment Lyme disease syndrome 0.15
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 0.15


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