Gene Query: POLA2

Dataset Description Geneva Score
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 38.45
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 31.76
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 27.41
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 25.63
Transcriptomes analysis for the regulation of Z36 induced autophagy in HeLa cell death 25.61
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 25.37
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 25.05
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 24.58
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 24.58
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 23.95
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 22.55
The regulartory role of ZCCHC24 in splicing machinery 21.41
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 21.37
ETV7 and interferon response 21.37
High-throughput RNA sequencing on circular RNA profiles of human pancreatic cancer cell lines and gemcitabine resistant pancreatic cancer cell lines. 21.07
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 21.02
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 20.16
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 19.69
Transcriptome analysis of U87 cells upon LINC00152 knockdown 19.52
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 19.16
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 18.3
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 18.21
Transcriptome analysis of immature and matured human oocytes from patients of young and advanced maternal age 18.14
MeRIP-seq for heat shock in B-cell lymphoma cells 17.97
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 17.71
H3K27ac ChIP-Seq and mRNA-Seq analysis of five human B-lymphoblastoid cell lines (LCLs) prepared from the same healthy male individual (CEPH/UTAH). 16.92
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 16.37
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 16.35
Hijacking of stress response machinery by oncogenes in acute leukaemia 16.35
Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation 16.34
A549 cells and MSR-A549 cells 16.07
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 16.07
EWSR1 influences alternative splicing through direct and indirect mechanisms 16.05
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 15.79
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 15.76
Transcription control by the ENL YEATS domain in acute leukemia 15.76
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 15.62
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 15.53
Transcriptomic analyssis following EHMT1/2 inhibition 15.21
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors [RNA-seq] 15.18
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors 15.18
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 15.17
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 14.99
Identification of global regulators of T-helper cell lineage specification 14.99
Differential gene expression analysis between proliferating and quiescent human dermal fibroblasts 14.78
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 14.58
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 14.3
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 14.28
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 14.24
Estrogen response in breast cancer cell line MCF-7 is dependent on NR2F2 [RNA-seq] 13.98
NR2F2 study 13.98
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 13.88
MYOD Remodeling of the Genome Architecture during Myogenic Conversion of Somatic Cells 13.69
A common cell state in Triple Negative Breast Cancers represents a druggable vulnerability 13.59
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 13.39
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 13.25
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 13.18
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 13.06
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 13.06
RNAseq Study in CC-671 Treated Cal-51 Cells 12.97
MYOD Gene Expression Regulation during Myogenic Conversion of Fibroblasts 12.88
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 12.86
RNAseq analysis of ESRP regulated splicing events in prostate cancer 12.86
Transcriptome analysis of BAP1 knockout and restoration 12.84
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 12.84
Genome-wide analysis of ferroptosis related genes in liver cancer cells. 12.56
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 12.56
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 12.44
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation 12.29
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq] 12.29
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 12.27
Conservative alteration of chromosomal expression pattern across human solid tumor types 11.84
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 11.76
Functional role of SLIT2 and ROBO1 in trophoblasts 11.74
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 11.72
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 11.71
Alu RNA modulates the expression of cell cycle genes in human fibroblasts 11.7
Downregulation of DDX5/DDX17 and REST 11.61
BRG1 governs Glucocorticoid Receptor interactions with chromatin and pioneer factors across the genome 11.6
A Unique Epigenomic Landscape Defines Human Erythropoiesis 11.57
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 11.57
Genome wide expression change by RNF168 knocking down in MCF-7 cells 11.53
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 11.52
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 11.36
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 11.36
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 11.35
Re-Wiring 3D Nuclear Architecture by a Single Transcription Factor during Somatic Cell Reprogramming 11.19
Alternative splicing of differentiated myeloid cell transcripts after infection by Anaplasma phagocytophilum impacts a selective group of cellular programs 11.03
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 11.0
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 10.98
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 10.96
Genome-wide chromatin analysis of Ewing sarcoma 10.96
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 10.83
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 10.83
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 10.77
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 10.76
Impact of DNA MMR activity on antiviral gene expression in H441 cells infected with influenza A virus 10.66
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 10.6
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 10.59
Active translatome profiling with RiboLace in MCF7 cells 10.54
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 10.5
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 10.4
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 10.39
Estrogen receptor and mTOR signaling rewires cancer metabolism in obesity-associated breast cancer 10.32
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 10.3
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 10.29
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 10.25
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 10.2
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 10.2
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 10.13
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 9.98
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 9.95
Knockdown of FOXP1 promotes the development of lung adenocarcinoma 9.92
Response of HEK293 Freestyle cells to 36 h of culture in Zn(II)-depleted Freestyle medium 9.91
XPO1 inhibition antagonizes MCL via nuclear retention of IkB: Selinexor demonstrates antitumor activities in both ibr-sensitive and ibr-resistant tumor cells 9.87
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 9.86
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 9.86
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 9.8
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 9.8
4sUDRB-seq: measuring transcription elongation and initiation genomewide 9.77
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 9.68
SRSF2 mutations impair hematopoiesis and alter exon recognition 9.65
Gene expression analysis of ER+ and ER- breast cancer cell lines with acquired resistance to palbociclib 9.65
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 9.65
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 9.62
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 9.58
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 9.55
Differential gene expression of human melanoma cells [RNA-seq] 9.48
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 9.48
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 9.42
RNA-seq differential expression studies: more sequence, or more replication? 9.32
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 9.24
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 9.23
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 9.16
Transcriptome analysis of VCaP xenografts resistant to dual therapy with abiraterone and enzalutamide 9.07
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 9.06
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 9.06
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 9.04
The Promyelocytic Leukemia Zinc Finger Dependent Transcriptome during Human Endometrial Stromal Cell Decidualization 9.01
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 9.0
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 8.96
Steroid Receptor Coactivator-2 Regulated Transcriptome in Human Endometrial Stromal Cells 8.9
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Human_RWPE1_RNA-Seq) 8.86
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation 8.86
The myelin protein PMP2 is regulated by SOX10 and drives melanoma cell invasion 8.83
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 8.79
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 8.78
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 8.77
RNA-seq of resting and activated CD4+ T cells +-JQ1 8.77
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 8.73
WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription 8.66
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 8.6
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 8.6
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 8.59
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 8.54
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 8.52
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 8.48
Overexpression of NFIB and YBX1 in MCF-7 cells 8.46
Genome-wide transcriptional response to random aneuploidy in human cells 8.35
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 8.34
RNA-seq analysis of differentiating human erythroblasts 8.33
mRNA-seq from Nutlin-3a, doxorubicin, and DMSO treated HCT116 p21-/- cells 8.32
Seletive inhibition of CDK9 in DLBCL cell lines 8.27
STRIPAK directs PP2A activity to promote oncogenic transformation 8.27
RNA-seq in SUNE-1 cells after downregulation of DANCR expression 8.2
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 8.06
LncRNA-GAS5 negative regulation of YAP-target genes expression 8.01
The landscape of alternative splicing in aggressive prostate cancers 7.97
Small molecule targets TMED9, promotes lysosomal degradation to reverse proteinopathy 7.94
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 7.93
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 7.93
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 7.9
Transcriptome-wide identification of CELF2 functional targets in T cells 7.87
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 7.85
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 7.83
ChIPseq and RNAseq analysis of T47D cells with/without silencing TRPS1/CHD4 7.81
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 7.8
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 7.72
Downregulation of LATS kinases alters p53 to promote cell migration 7.66
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 7.64
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 7.64
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 7.64
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 7.61
Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation 7.54
Gene expression comparison of resting human peripheral-blood NK cells and activated counterparts 7.52
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 7.51
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 7.5
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 7.5
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 7.5
EWS-Fli and LNC regulated genes in comparison to GFP samples 7.48
miRNA-1343 attenuates pathways of fibrosis by targeting the TGF-beta receptors [RNA-seq] 7.39
MYCi361 regulates MYC target genes 7.37
Transcriptome profiling identified a 3-lncRNA regulatory network in transthyretin against glucose induced hRECs dysfunction 7.37
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 7.36
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 7.31
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 7.29
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 7.29
RNA expression profiling of human mPB or CB-derived CD34+ cells treated with UM171 at different doses 7.28
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 7.26
BCL11B 7.25
Knockout of miR-221 and miR-222 reveals overlapping and specific function between paralogous miRNAs 7.25
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 7.25
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 7.19
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 7.19
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 7.09
Co-regulation of splicing by Rbfox1 and hnRNP M 7.09
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 7.06
RNA-seq profile of expanded human ST2-transduced Tregs cultured with IL-2 and TCR in the presence or absence of IL-33 7.01
Modulation of nonsense-mediated decay by rapamycin 7.01
Genome wide transcriptome analysis of palbociclib or GSK3326595 treated A375 cells [Palbociclib_GSK_RNASeq] 7.0
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 7.0
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 6.98
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 6.98
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 6.96
Entrectinib Resistance in a Neuroblastoma Xenograft Model 6.95
Global gene expression profile of dasatinib-resistant RCH-ACV cells 6.95
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 6.94
Total RNA-seq in ALL-SIL upon JQ1 inhibition 6.93
Gene induction by the USP6 oncogene in response to interferon 6.91
3’READS+, a sensitive and accurate method for 3’ end sequencing of polyadenylated RNA 6.91
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 6.91
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 6.91
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 [RNA-seq] 6.91
Identifying lincRNA as prognostic biomarker for clear cell renal cell carcinoma 6.85
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 6.83
Effect of Influenza virus infection on lncRNA expression in A549 cells 6.82
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 6.82
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer 6.81
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer [RNA-Seq] 6.81
A code of mono-phosphorylation modulates the function of RB. 6.76
Identification of Sin3B regulated genes during quiescence 6.67
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 6.63
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 6.63
Transcriptome-wide modulation of splicing by the exon junction complex 6.62
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 6.6
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 6.6
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 6.59
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 6.49
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 6.47
Genes altered in expression by Cisplatin treatment in lung cancer cell lines 6.46
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 6.42
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 6.41
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 6.4
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 6.39
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq B-ALL) 6.37
BASP1 modifies the Tamoxifen response 6.36
Transcriptional profiles of normal human mature B cells 6.32
FGF2 induces migration of human bone marrow stromal cells by increasing core-fucosylations on N-glycans of integrins 6.32
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity 6.31
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 6.31
Cystathionine-β-Synthase Promotes Colon Carcinogenesis 6.3
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 6.3
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 6.27
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 6.27
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 6.21
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 6.19
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 6.17
Histone Demethylases KDM3A and KDM4C regulate mesenchymal stromal cell senescence and bone aging through condensin-mediated heterochromatin organization 6.16
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 6.12
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 6.11
MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway 6.1
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 6.09
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 6.09
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia 6.08
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia (RNA-seq) 6.08
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy 5.96
Gene expression profile of multiple myeloma cell lines treated with CB-5083 5.9
Genome-wide analysis of Dengue virus 2 infected cells 5.83
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 5.82
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 5.82
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 5.81
HOXC6 affects the malignant phenotype of esophageal squamous cell carcinoma cells 5.78
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 5.75
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 5.74
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 5.74
A faithful in vivo model of human MLL-AF4 proB acute lymphoblastic leukemia 5.71
IRF2 is a master regulator of human keratinocyte stem cell fate [RNA-seq] 5.7
IRF2 is a master regulator of human keratinocyte stem cell fate 5.7
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 5.7
Exploring ILF2 regulatory genes by next-generation sequencing 5.69
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 5.68
Neurofibromin is an Estrogen Receptor alpha Transcriptional Co-repressor in Breast cancer 5.64
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 5.6
Identification of differential expressed genes of JQ1 or JQ1+Bortezomib in colorectal cancer cells 5.57
ARS2 is a general suppressor of pervasive transcription [RNAseq] 5.57
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 5.53
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 5.53
RNA-seq analysis of uveal melanoma cells treated with FR900359 5.51
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 5.5
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 5.49
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 5.47
MCF-7 as a model for functional analysis of breast cancer risk variants 5.43
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation 5.43
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation [RNA-seq] 5.43
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 5.4
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 5.4
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 5.38
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 5.33
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 5.33
p53 activity results in DNA replication fork processivity 5.18
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 5.18
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 5.13
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 5.12
HEXIM1 is induced by DHODH inhibition to suppress melanoma 5.11
HEXIM1 is induced by DHODH inhibition to suppress melanoma [Gro-Seq] 5.11
PTHrP overexpression in MCF7 cells 5.09
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity 5.04
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 5.03
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 5.02
Integrin signaling regulates YAP/TAZ to control skin homeostasis 4.98
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine resistant breast cancer 4.95
Epigenetic reprogramming at estrogen-receptor binding sites alters the 3D chromatin landscape in endocrine resistant breast cancer [RNA-seq] 4.95
KLF6-dependent transcription in renal cancer cells 4.89
RNA-seq of hiPSCs-derived NPCs from 3 pairs of dizygotic discordant twins for Congenital Zika syndrome 4.88
LIN28A Over-expression RNAseq 4.87
Human HAP1 cells before and after nutrient deprivation 4.86
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation 4.86
Expression and functions of long noncoding RNAs during human T helper cell differentiation 4.86
BACH2 in human plasma cell fate decision 4.79
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 4.79
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 4.76
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 [RNA-seq] 4.76
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 4.76
Silencing p300 in MCF7 cells to study expression and alternative splicing 4.71
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (TLR perturbation Bulk RNA-Seq) 4.67
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 4.64
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 4.64
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 4.62
METTL3 and WTAP 4.59
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression 4.56
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression [RNA-Seq] 4.56
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 4.53
Genome-wide RNA deep sequencing of CAL-101 or AKTi primed human T cells in comparison to traditionally expanded T cells 4.52
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 4.49
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with tcons_00001221 shRNA or control shRNA 4.48
Microvesicle-mediated delivery of miR-1343: impact on markers of fibrosis 4.43
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 4.43
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 4.41
Sequencing of ponatinib-resistant LC-2/ad derivatives (PR1 and PR2) and parental LC-2/ad cells 4.35
Next generation sequencing on knockdown of AC093323.3 in lung cancer cells 4.32
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 4.29
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 4.28
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 4.19
Determining effects of microbial metabolite, Urolithin A on colon epithelial cells 4.16
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 4.16
RNA-seq of human foreskin fibroblast cells lacking RB, p130, and p107 treated with doxorubicin. 4.03
Analysis of active enhancers and direct androgen receptor target genes in VCaP prostate cancer cells 4.02
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 4.01
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 4.01
Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis 3.95
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 3.89
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 3.89
The lung-enriched p53 mutants V157F and R158L/P regulate a novel transcriptome in lung cancer 3.84
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 3.83
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 3.83
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 3.7
Whole transcriptome splicing analysis in isogenic lung epithelial and adenocarcinoma cell lines with or without a recurrent splicing factor mutation, U2AF1 (S34F) 3.69
Evolution of an lncRNA leads to a primate specific modulation of alternative splicing 3.56
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 3.55
miR941 overexpression experiment 3.55
U2AF1 mutations alter splice site recognition in hematological malignancies 3.5
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreas cancer 3.49
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 3.49
Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells 3.47
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 3.43
Decoding breast cancer tissue-stroma interactions using species-specific sequencing 3.42
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 3.38
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 3.35
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 3.35
Human cells contain natural double-stranded RNAs with potential regulatory capacity 3.35
O-glcnAc reprograms cellular energetics 3.35
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 3.34
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 3.28
MARS Seq data from human cortical organoids 3.28
hiPSCs unravel aberrant TGFβ signaling as an etiology of left ventricular non-compaction 3.26
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export II 3.23
β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells 3.22
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 3.02
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 3.02
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 3.01
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 3.01
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 3.0
KLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the bone 2.97
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 2.95
RNA-sequencing analysis of glucose and acetate regulated transcripts in glioblastoma cells 2.88
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 2.86
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 2.84
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 2.84
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma [RNA-seq] 2.75
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma 2.75
FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA 2.73
Gene expression profile in FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA using RNA-seq. 2.73
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 2.68
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 2.67
K562 polyA RNA-Seq 2.62
Integration of genome-wide DNA methylome and transcriptome of human intestinal fibroblasts reveals novel candidate gene signatures in Crohn’s disease-associated fibrosis 2.57
Suppression of the FOXM1 transcriptional program via novel small molecule inhibition 2.56
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 2.55
Small-molecule targeting of brachyury transcription factor addiction in chordoma 2.54
RNA-sequencing experiment: Treatment of MCF-7 breast cancer cells with the novel small molecule ZNA 2.54
Proteomics identifies a marker signature of MAPKi resistance in melanoma 2.47
Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells 2.47
Ro60-knockout cells 2.47
Next Generation Sequencing Facilitates Quantitative Analysis of UVB(20mJ/cm2 and 40mJ/cm2) exposed and untreated HaCaT keratinocytes Transcriptomes 2.47
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 2.45
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 2.44
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner 2.41
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 2.39
Folate modulation induces chromosomal instability and higher proliferation of immortalized human keratinocytes 2.23
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 2.2
Gene expression from AsPC-1 cells treated with PTC596 and DMSO 2.15
The circadian transcriptional landscape in primary human mammary epithelial cells 2.1
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 2.01
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 1.99
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 1.98
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 1.95
Loss of CREBBP results in gene expression repression in lymphoma cells 1.95
The Genetic Landscape of Diamond-Blackfan Anemia 1.93
TALEN-based knockout of mir-141 and mir-200c in SK-BR-3 cells 1.92
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 1.77
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 1.67
Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s 1.66
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 1.65
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 1.65
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 1.61
The mRNA export receptor NXF1 coordinates transcriptional dynamics, alternative polyadenylation and mRNA export 1.61
Low-dose decitabine priming endows CAR T cells with enhanced and persistent anti-tumor potential by epigenetic reprogramming 1.59
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 1.56
ADAR1-editing in HeLa, p150-KO and ADAR1-KO transcriptomes 1.53
ADAR1-editing of cellular and measles virus-derived duplex RNA 1.53
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 1.5
RNA deep sequencing analysis of glioma stem cells(GSCs) and non-GSCs 1.45
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 1.44
RNA sequencing of human pancreatic cancer cell lines 1.42
Functional significance of the HIV-1 Tat signature amino acid residues 1.4
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 1.38
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 1.31
RNA-seq analysis upon ARID1B overexpression 1.23
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 1.16
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 1.15
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 1.14
Regulating Interleukin-2 activity with engineered receptor signaling clamps 1.13
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 1.09
Antioxidant metabolism in activated CD8+ T cells regulates stem-like human memory T cell formation and anti-tumor immunity 1.09
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 1.09
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 1.06
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 1.04
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 1.0
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 1.0
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 0.97
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 0.97
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 0.95
Regulation of poly(A) tail and translation during the somatic cell cycle 0.94
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  0.91
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 0.91
Proliferation-correlated expression 0.84
Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify 0.84
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.84
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 0.83
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 0.83
Transcriptomic analysis of LSD1 0.79
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq] 0.75
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations 0.75
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 0.7
Comparative Analysis of Cas9 Activators Across Multiple Species 0.63
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.6
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 0.58
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 0.57
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing (RNA-seq) 0.53
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing 0.53
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 0.49
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 0.49
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 0.49
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 0.44
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 0.44
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.42
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.42
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 0.35
CUREfast: Accelerating research with families 0.35
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 0.33
RNA-seq analysis reveals endogenous aryl hydrocarbon receptor regulation is highly associated with eicosanoid synthesis and tumor necrosis factor activity in MCF-7 cancer cells 0.32
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma 0.3
Transcriptome profiling (RNA-seq) of CREBBP+/+ and CREBBP+/- clones of U2932 DLBCL cell line 0.3
The DPYSL2 gene connects mTOR and schizophrenia 0.3
Clinker: visualizing fusion genes detected in RNA-seq data 0.29
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 0.28
The transcriptome of human endometrial mesenchymal stem cells under TGFβR inhibition reveals improved potential for cell-based therapies 0.25
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 0.24
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 0.2
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 0.2
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 0.17
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 0.14
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.13
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 0.12
Transcriptome-wide analysis to determine miR-200a targets in melanoma cell lines 0.11
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 0.1
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 0.06
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 0.05
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 0.02
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 0.02


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