Gene Query: POLE2

Dataset Description Geneva Score
Short and Long RNA sequencing of human mature erythrocytes 15.21
Gene-Centric Functional Dissection of Human Genetic Variation Uncovers Regulators of Hematopoiesis 14.86
BRG1 governs Glucocorticoid Receptor interactions with chromatin and pioneer factors across the genome 11.79
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 11.15
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 10.87
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 9.96
RNA sequencing of primary human platelets and in vitro cell lines 9.52
Differential expression of long non‑coding RNA and mRNA in children with Henoch‑Schönlein purpura nephritis 9.48
RNA-seq Analysis of Castration-Resistant Prostate Cancer With Knock-down of E2F1 8.21
Transcription control by the ENL YEATS domain in acute leukemia 7.9
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 7.9
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 7.75
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 7.75
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 7.74
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 7.64
Hijacking of stress response machinery by oncogenes in acute leukaemia 7.64
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 7.06
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 7.02
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 6.92
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 6.81
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile [mRNA-Seq] 6.6
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile 6.6
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 6.58
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 6.44
Developmental stage specific chromosome architecture in human erythroid cells 6.44
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 6.41
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 6.4
RNA-seq analysis of differentiating human erythroblasts 6.37
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 6.25
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 5.76
LIN28A Over-expression RNAseq 5.35
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 5.33
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 5.21
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 5.05
Nucleoporin-mediated regulation of cell identity genes 4.97
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 4.87
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 4.61
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 4.43
MUC1-C Drives Lineage Plasticity in Progression to Neuroendocrine Prostate Cancer 4.4
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 4.37
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 4.37
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived SPINK1 4.37
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 4.35
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 4.34
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 4.33
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 4.31
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 4.23
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 4.22
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype 4.2
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype [RNA-Seq] 4.2
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 4.18
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 4.05
Genome-wide discovery of human splicing branchpoints 3.95
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 3.88
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 3.87
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 3.81
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 3.81
A Unique Epigenomic Landscape Defines Human Erythropoiesis 3.76
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 3.76
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 3.75
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 3.71
A549 cells and MSR-A549 cells 3.71
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 3.61
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 3.59
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 3.59
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 3.56
Genome-wide RNA-seq from GALNT14-depleted and GALNT14 overexpressing MDA-MB-231 LM2 and Par cells 3.55
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 3.51
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 3.5
A transcriptome-wide divergence in protein translation scales with LIN28B expression 3.47
Consequences of Ribosomal Protein Haploinsufficiency in Human Hematopoiesis 3.46
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 3.43
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 3.34
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 3.33
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  3.31
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 3.3
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 3.3
PTHrP overexpression in MCF7 cells 3.29
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 3.29
Identification of global regulators of T-helper cell lineage specification 3.29
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 3.27
IGF2BP3 controls cancer cell invasiveness by modulation RISC function 3.26
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 3.26
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 3.24
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 3.23
TGF-β regulation of miRNA expression in pancreatic cancer 3.2
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 3.18
RNA-seq of resting and activated CD4+ T cells +-JQ1 3.15
Transcriptional changes in lymphoma cells induced by LSD1 depletion 3.13
Histone demethylase LSD1 is required for germinal center formation and BCL6 driven lymphomagenesis 3.13
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [short_hairpins_RNA-seq] 3.1
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 3.09
Changes in CD34 and Erythroid Progenitor Transcriptome After RUNX3 Kock-down 3.05
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 3.03
An atlas of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2 3.01
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 3.0
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 2.96
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 2.95
RNA-seq analysis to identify the genes regulated by p53-SET interplay 2.94
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 2.91
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 2.91
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 2.91
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 2.91
The BCL6 RD2 domain governs commitment of activated B-cells to form germinal centers 2.89
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 2.88
Oncogenic MYC induces a dependency on the spliceosome in human cancer 2.88
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 2.86
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 2.81
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 2.8
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 2.8
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 2.78
Gene expression profile in breast cancer cells 2.78
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 2.78
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 2.78
MYCi361 regulates MYC target genes 2.77
RNAseq Study in CC-671 Treated Cal-51 Cells 2.76
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 2.74
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 2.74
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 2.72
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 2.67
SETDB2 links E2A-PBX1 to cell cycle dysregulation in acute leukemia through CDKN2C repression [sequencing] 2.65
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 2.63
Overexpression and knockdown experiment for circCSNK1G3 2.63
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 2.59
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 2.59
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 2.56
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 2.56
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia (RNA-seq) 2.56
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia 2.56
Non-synchronized cell cycle transcriptomics in U2OS and HeLa cancer cells 2.55
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 2.53
Global gene expression profile of dasatinib-resistant RCH-ACV cells 2.52
hTERT promotes cell adhesion and migration independent of telomerase activity 2.52
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 2.5
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 2.5
Human Treg NaCl stimulation 2.49
Total RNA-seq in ALL-SIL upon JQ1 inhibition 2.46
Transcriptomic analysis of T84 colon carcinoma cell line treated with trametinib, JQ1 or their combination 2.45
Total RNA-seq in ALL-SIL upon TLX1 knockdown 2.44
Seletive inhibition of CDK9 in DLBCL cell lines 2.4
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 2.36
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 2.36
Hypoxic transcriptome of SQ20B human head and neck cancer cells 2.36
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 2.35
Histone H3 Lysine4 Acetylation-Methylation Dynamics Define Breast Cancer Subtypes 2.34
Histone H3 lysine 4 acetylation-methylation dynamics define breast cancer subtypes [RNA-seq] 2.34
Flura-seq identifies organ-specific adaptations in metastasis-initiating cells 2.34
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 2.33
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 2.32
FBXW7 modulates stress response by post-translational modification of HSF1 2.32
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 2.31
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 2.3
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 2.3
transcriptomic profiling of HEK293 cells upon individual knockdown of the splicing factors RBM17, U2SURP or CHERP 2.29
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 2.28
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 2.24
The cohesin complex prevents Myc-induced replication stress 2.22
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 2.21
N6-methyladenine DNA Modification in Glioblastoma 2.21
MYC interacts with the G9a histone methyltransferase to drive transcriptional repression and tumorigenesis 2.21
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 2.2
Silencing p300 in MCF7 cells to study expression and alternative splicing 2.19
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 2.18
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 2.17
RNA-Seq and ATAC-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 2.16
RNA-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 2.16
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 2.16
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 2.15
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 2.14
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 2.13
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 2.13
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 2.11
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 2.1
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 2.1
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 2.1
Cerebellar differentiation in Ataxia-Telangiectasia 2.09
Accurate annotation of human protein-coding small open reading frames 2.08
Expression changes in melanoma cell lines pre MAPKi treatment vs. post-MAPKi resistance (RNA-seq_CellLine.batch2) 2.08
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 2.07
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 2.07
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 2.06
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 2.06
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 2.06
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 2.05
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 2.04
EP400 is required for Max and MCPyV mediated gene activation 2.04
Peripheral whole blood mRNAs and lncRNAs expression analysis in eosinophilic asthmatics 2.04
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 2.03
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 2.0
Small molecule targets TMED9, promotes lysosomal degradation to reverse proteinopathy 1.99
Regulation of hypoxia-inducible factor activity by ZMYND8 1.98
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 1.98
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 1.96
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma [RNA-seq] 1.95
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma 1.95
Spliceosomal disruption of the non-canonical BAF complex in cancer 1.95
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 1.93
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 1.93
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 1.92
microRNA suppresses prostate cancer stem cells and metastasis by inhibiting a cohort of pro-metastasis targets including CD44, Rho GTPases and EZH2 1.91
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 1.91
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 1.91
Transcriptome-wide identification of CELF2 functional targets in T cells 1.9
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 1.9
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 1.88
Transcriptomic analysis of trametinib-resistant HCT116 colorectal carcinoma cells compared to the parental control cells 1.86
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 1.85
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 1.85
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 1.84
Integrin signaling regulates YAP/TAZ to control skin homeostasis 1.84
Genome-wide CRISPR-Cas9 screen identifies SLC1A3 as a key contributor to L-asparaginase Resistance in Solid tumors 1.83
KSDM1b Role in Ewing Sarcoma 1.81
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1 1.8
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine resistant breast cancer 1.8
Epigenetic reprogramming at estrogen-receptor binding sites alters the 3D chromatin landscape in endocrine resistant breast cancer [RNA-seq] 1.8
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 1.77
Genes altered in expression by Cisplatin treatment in lung cancer cell lines 1.77
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 1.76
RNA-seq of cells with TET1 knockout 1.74
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 1.73
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 1.73
Genome wide expression change by RNF168 knocking down in MCF-7 cells 1.73
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 1.72
Gene expression changes after depletion of Cyclin F and atypical E2Fs in HeLa cells. 1.72
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 1.71
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 1.71
Genome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA 1.71
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 1.71
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-seq of KLF6 KO) 1.71
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 1.71
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 1.71
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 1.7
The influence of PPFIA1 silencing to gene expression in breast carcinoma cell line and head and neck squamous cell carcinoma cell lines by RNA-sequencing in three dimensional collagen I 1.69
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 1.69
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma 1.68
Functional significance of the HIV-1 Tat signature amino acid residues 1.68
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 1.68
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 1.68
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 1.68
Physiologic expression of Sf3b1K700E causes impaired erythropoieses, aberrant splicing, and sensitivity to pharmacologic spliceosome modulation 1.68
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 1.67
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 1.65
GATA3-mediated chromatin reprogramming in breast cancer cells 1.65
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 1.63
A map of gene expression in neutrophil-like cell lines 1.63
Regulation of protein translation during mitosis 1.63
Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance 1.62
Single-cell RNA Sequencing Resolves Spatiotemporal Development of Pre-thymic Lymphoid Progenitors and Thymus Organogenesis in Human Embryos 1.62
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 1.62
A role for ZNF598 in post-transcriptional gene regulation 1.61
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 1.61
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 1.61
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 1.61
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 1.6
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 1.6
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 1.6
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 1.59
Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma engages the ER-stress response II 1.59
MYC dependent mRNA translation shapes gene expression and cell biology 1.59
Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth 1.57
Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic co-culture 1.57
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 1.56
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 1.56
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 1.55
In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity 1.54
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 1.54
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 1.54
Cancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor development 1.54
Biased Expression of the FOXP3Δ3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance 1.53
Oncogenic changes and EMT in normal human bile duct epithelial cells are caused by parasite-derived materials and N-nitrosodimethylamine 1.53
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 1.52
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [polyA RNA-seq] 1.5
A sister of NANOG regulates genes expressed in pre-implantation human development 1.5
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 1.5
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 1.5
Treatment of prostate cancer cells with S-adenosylmethionine leads to genomewide alterations of transcription profiles 1.48
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 1.48
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 1.48
Effect of CHKA knockdown on C4-2 cell transcriptome 1.47
Gene expression analysis of dengue-infected cells 1.46
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity 1.45
4sU-seq of HFF exposed to salt and heat stress 1.45
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer 1.44
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer [RNA-seq] 1.44
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 1.44
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 1.44
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 1.42
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 1.42
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 1.42
K562 polyA RNA-Seq 1.42
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 1.41
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 1.4
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 1.4
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 1.39
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors 1.39
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 1.38
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 1.37
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 1.36
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer 1.35
Identification of long noncoding RNAs regulated by p53 1.35
The transcriptome and chromatin accessbility landscape of mammalian germline 1.34
SRSF2 mutations impair hematopoiesis and alter exon recognition 1.3
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 1.29
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 1.27
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 1.27
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 1.26
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 1.26
Illumina Total RNA-seq in HeLa 1.23
Neonatal and adult human testis defined at the single-cell level 1.23
RNA-seq of YB5 cells treated with Proscillaridin A 1.21
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 1.21
Cancer-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1 1.19
RNA expression profiling of human mPB or CB-derived CD34+ cells treated with UM171 at different doses 1.18
Systematic discovery of endogenous human ribonucleoprotein complexes 1.14
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 1.13
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 1.12
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 1.11
Ribosome profiling upon inhibition of eIF4A 1.1
Comparative Transcriptomic Analysis of Hematopoietic System Across Species by Microwell-Seq 1.1
A novel compound that blocks HIV-1 replication inhibits the splicing regulatory function of SRSF10 1.08
Ro60-knockout cells 1.07
ETS family proteins bind glucocorticoid receptor: relevance for treatment of Ewing sarcoma 1.07
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 1.07
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 1.07
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.07
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 1.06
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 1.06
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 1.05
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 1.05
Effect of PDZ domain binding Kinase inhibition using TOPK-32 (called PBKi) on C4-2 cell transcriptome 1.05
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 1.04
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 1.03
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 1.02
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with pancreatic carcinoma 1.02
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 1.01
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 1.01
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 1.0
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 1.0
An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans. 1.0
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 0.99
Downregulation of DDX5/DDX17 and REST 0.98
An siRNA screen identifies CHD4 as a target for epigenetic therapy 0.97
RNA sequencing of bone marrow CD34+ cells from myelodysplastic syndrome patients with and without SF3B1 mutation and from healthy controls 0.95
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 0.95
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 0.94
The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells 0.94
Identification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression 0.94
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 0.94
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 0.93
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 0.92
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 0.91
Loss of CREBBP results in gene expression repression in lymphoma cells 0.91
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 0.9
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 0.89
ETS1 acts as a tumor suppressor in breast cancer by inhibiting growth-related factors 0.88
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 0.88
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 0.88
RNA-seq of MDA-MB-231 cells with TET1 knockout 0.88
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 0.88
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 0.88
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 0.87
RNA-Seq of PRMT1 overexpression ECA109 cells 0.87
lncRNA expression analysis in patients with eosinophilic and neutrophilic asthma 0.86
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 0.86
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 0.85
single cell RNA-seq from GM12878 (ENCSR673UIY) 0.85
Effect of from Human Umbilical Vein Endothelial Cells 0.85
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 0.83
Effect of estrogen (E2) treatment on the C4-12 relative to the MCF7 cells 0.82
Highly-motile versus unsorted MDA-MB-231 breast cancer cells 0.81
Human Treg IL-12 stimulation 0.8
Transcriptional landscape changes during human embryonic stem cell derivation 0.8
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 0.8
Real-time observation of light-controlled transcription in living cells 0.79
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 0.79
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability 0.79
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability [ RNA-seq] 0.79
RNA-seq analysis of control and CDK12-depleted ovarian cancer cells 0.79
Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells 0.78
Vitamin C Promotes Apoptosis in Breast Cancer Cells by Increasing TRAIL Expression 0.77
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 0.76
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 0.74
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 0.74
Ribosomal protein RPL26 is the principal target of UFMylation 0.74
O-glcnAc reprograms cellular energetics 0.74
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 0.73
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 0.72
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 0.7
Rnase L reprograms translation by widespread mRNA turnover escaped by antiviral mRNAs 0.69
POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells 0.68
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 0.68
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 0.67
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 0.67
The lung-enriched p53 mutants V157F and R158L/P regulate a novel transcriptome in lung cancer 0.67
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies [RNA-Seq] 0.65
Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies 0.65
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination 0.64
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination (RNAseq) 0.64
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations 0.63
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations [RNA-Seq] 0.63
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 0.63
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 0.63
Expression levels of genes of NKG2C+ NK cells after in vitro treatment 0.63
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation (Ribo-seq, RNA-seq) 0.63
p53 activity results in DNA replication fork processivity 0.6
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 0.6
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 0.6
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 0.59
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 0.59
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 0.59
LIN28A modulates splicing and gene expression programs in breast cancer cells 0.57
LIN28A modulates splicing and gene expression programs in breast cancer cells [RNA-Seq] 0.57
Modulation of nonsense-mediated decay by rapamycin 0.57
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 0.57
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 0.55
Carcinoma-astrocyte gap junctions promote brain metastasis by cytosolic dsDNA response transfer 0.55
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 0.55
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 0.55
HEK293 TFAM Knockout Expression Study 0.54
Transcriptomic analysis of LSD1 0.54
Sequence dependency and regulatory function of dimeric NOTCH1/RBPJ complexes on coding and non-coding transcription in T-lymphoblastic leukemia 0.53
RNA isoform screens reveal the essentiality and tumor suppressor activity of ultraconserved poison exons 0.51
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 0.51
Specific molecular signatures underlie response to decitabine in CMML 0.5
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 0.5
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 0.49
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 0.49
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 0.49
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity 0.49
Single-Cell reconstruction of differentiation trajectory reveals essential dynamics in human cardiac lineage commitment 0.48
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma non-targeting shRNA negative control (SHC002V) with puromycin selection RNAseq 0.47
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 0.46
High-resolution comparative analysis of great ape genomes 0.45
Transcriptional response of human endocervical epithelial A2EN cells to infection with wild-type or CpoS-deficient Chlamydia trachomatis L2/434/Bu 0.45
JAG1 Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium 0.45
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (TLR perturbation Bulk RNA-Seq) 0.45
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 0.44
Gene expression changes due to PARP knockdown in human cells 0.44
RNA-seq reveals abundant circRNA, lncRNA and mRNA in blood exosomes of patients with colorectal carcinoma 0.44
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 0.43
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 0.42
Transcriptome-wide modulation of splicing by the exon junction complex 0.4
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 0.38
CDK12 mediated transcriptional regulation in U2OS cells 0.37
RNA-seq analysis of control and Myc-induced U2OS cells 0.37
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 0.36
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 0.36
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 0.35
Oncogenic roles of ARID5B in T-ALL 0.35
RNA-seq analysis in knockdown Jurkat samples for each factor of TAL1 complex 0.35
Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity 0.35
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.35
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.35
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.33
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.33
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 0.33
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation II 0.32
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 0.32
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 0.3
rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome 0.29
Transcriptomic analysis of ERR alpha orphan nuclear receptor 0.29
A bioinformatics approach reveals novel mechanisms of the OVOL transcription factors in the regulation of epithelial-mesenchymal cell programming and cancer progression. 0.29
RNA-sequencing of tamoxifen-resistant and -sensitive breast cancer cell lines. 0.29
RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs 0.27
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 0.25
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 0.25
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 0.25
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 0.25
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 0.24
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 0.24
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 0.23
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 0.22
Comprehensive comparative analysis of 5’ end RNA sequencing methods 0.21
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 0.21
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 0.21
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 0.2
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 0.18
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 0.14
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 0.12
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 0.12
A20 regulates canonical wnt-signaling through an interaction with RIPK4 0.12
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 0.1
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 0.1
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 0.09
Mutated H3 Histones Drive Human Pre-Leukemic Hematopoietic Stem Cell Expansion And Promote Leukemic Aggressiveness 0.09
Human Adult Sorted Live Cell Erythroblasts RNA-Seq. 0.06
microRNAs with an AAGUGC seed motif constitute an integral part of a signaling network driving NSCLC cell proliferation 0.06
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.06
Myc activation coordinates gene transcription and protein translation responses 0.05
Single-Cell Genotyping of Transcriptomes 0.04
RNA-seq of Single-Cell Genotyping of Transcriptomes 0.04
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.04
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 0.03
Effect of BB608 on Gene Expression in HNSCC Cell Line 0.03
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.02
Function and hormonal regulation of GATA3 in human first trimester placentation 0.02
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.02
SNHG5 siRNA knock down in HCT116 cells 0.02
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 0.01
Folate modulation induces chromosomal instability and higher proliferation of immortalized human keratinocytes 0.01


Contact Us

For scientific and technical queries contact Butte Lab @UCSF


Cite GENEVA Tool

Manuscript in Preparation