Gene Query: POLR2D

Dataset Description Geneva Score
RIG-I and MDA5 fRIP during KSHV lytic reactivation 42.76
Nrf2 regulated genes in A549 cells 40.55
Identification of Nrf2 regulated genes by RNA sequencing 40.55
Altering cancer transcriptomes using epigenomic inhibitors [RNA-Seq] 35.07
Altering cancer transcriptomes using epigenomic inhibitors 35.07
Effect of PRDM11 depletion in U2932 cells 34.39
miR941 overexpression experiment 32.83
NAD+ Analog-sensitive PARPs Reveal a Role for PARP-1 in Transcription Elongation 30.87
Low-Cell-Number, Single-Tube Amplification (STA) of RNAs Revealed miRNA Changes from Pluripotency to Endothelium 29.51
CD73 knockdown effect in pancreatic cancer cell lines 28.66
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HET] 27.0
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 26.3
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 26.3
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 25.06
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 24.94
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 24.84
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 23.95
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 21.18
Knockdown of FOXP1 promotes the development of lung adenocarcinoma 19.09
An atlas of TNF-α-responsive promoters and enhancers in the intestinal epithelial cell model Caco-2 19.02
Investigation into human Tra2 protein-dependent splicing in MDA-MB-231 cells using iCLIP and RNA-seq 17.61
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 16.19
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 16.19
Genome wide expression change by RNF168 knocking down in NEC cells 16.16
mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II transcription 15.89
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 15.88
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 15.88
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 15.73
Human HAP1 cells before and after nutrient deprivation 15.48
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation 15.48
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 15.43
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 15.28
Global transcriptional profiling changes upon knockdown of G9a in human non-small cell lung cancer cells 14.95
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 14.86
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 14.81
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 14.17
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 13.77
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 13.73
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis[Ribosome Profiling] 13.27
Mitochondrial dsRNA triggers antiviral signalling in humans 12.8
To investigate the decay constants (half-lives) of transcript isoforms generated by alternative polyadenylation in proliferating and quiescent cells 12.79
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 11.86
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 11.86
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 11.82
RNA-seq of YB5 cells treated with Proscillaridin A 11.72
Seletive inhibition of CDK9 in DLBCL cell lines 11.5
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation 11.36
Bladder cancer associated mutations in RXRA activate peroxisome proliferator-activated receptors 11.36
Nucleoporin-mediated regulation of cell identity genes 11.33
RNAseq Analysis in glioblastoma cells treated with Mepazine 11.2
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 11.2
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 11.19
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 10.54
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 10.51
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 10.3
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 10.27
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 10.2
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 10.08
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 10.08
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 10.01
Downregulation of DDX5/DDX17 and REST 9.94
RNA-seq of human foreskin fibroblast cells lacking RB and/or p130 after doxorubicin treatment 9.8
Targeting EZH2 in MYCN-amplified Neuroblastoma [RNA-seq] 9.7
Targeting EZH2 in MYCN-amplified Neuroblastoma 9.7
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 9.68
DRB/GRO-Seq -/+ UV 9.65
Systematic discovery of endogenous human ribonucleoprotein complexes 9.59
RNAseq of HEK293 cells after Chtop knockdown 9.57
Co-transcriptional loading of RNA export factors shapes the human transcriptome 9.57
Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate. 9.54
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 9.53
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 9.48
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 9.4
Human Induced Pluripotent Stem Cells Recapitulate Breast Cancer Patients’ Predilection to Doxorubicin-Induced Cardiotoxicity 9.38
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 9.35
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 9.35
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 9.35
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 9.35
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 9.33
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 9.33
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 9.33
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 9.3
EP400 is required for Max and MCPyV mediated gene activation 9.14
FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs 9.09
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 9.06
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 9.06
EWSR1 influences alternative splicing through direct and indirect mechanisms 9.03
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 8.86
Peptidomimetic blockade of MYB in acute myeloid leukemia 8.86
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation 8.85
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 8.84
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 8.82
Ultracentifugation and nanoscale deterministic lateral displacement (nanoDLD) of samples for exRNA analysis 8.81
Combined use of astragalus polysaccharide and berberine attenuates insulin resistance in IR-HepG2 cells via regulation of the gluconeogenesis signaling pathway 8.78
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 8.77
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 8.74
Paxillin regulates genomic networks in prostate cancer [LNCaP] 8.72
hnRNP C is a key regulator of protein synthesis in mitosis 8.72
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 8.71
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 8.6
A Unique Epigenomic Landscape Defines Human Erythropoiesis 8.6
RNA-seq in SUNE-1 cells after downregulation of DANCR expression 8.56
MYC dependent mRNA translation shapes gene expression and cell biology 8.39
Novel Targeting of Transcription and Metabolism in Glioblastoma 8.34
Global transcriptional profiling changes upon knockout of USP22 in human Non-small cell lung cancer cells 8.33
Effect of FGF13 depletion on the H460 cell line 8.32
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor 8.18
Effects of Cardiac Glycosides on RNA Expression in Prostate Cancer LNCaP-abl Cells 8.16
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 8.15
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 8.11
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 8.05
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 8.02
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia 8.0
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 7.98
Ribosomal footprinting of CN34-Parental and CN34-LM1a 7.93
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 7.89
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 7.86
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 7.86
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 7.81
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 7.81
Genome wide expression change by RNF168 knocking down in MCF-7 cells 7.74
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 7.73
Transcriptome Analysis of CircMRPS35 mediated mRNA expression profiles 7.66
RNA-seq of IL-4 stimulated human keratinocytes 7.64
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia 7.61
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia (RNA-seq) 7.61
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 7.55
Transcriptomic analyssis following EHMT1/2 inhibition 7.54
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer 7.52
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells [RNA-seq] 7.5
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells 7.5
The landscape of alternative splicing in aggressive prostate cancers 7.5
Transcriptomic analysis of ERR alpha orphan nuclear receptor 7.45
Ribosomal footprinting of MDA-Parental and MDA-LM2 7.39
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 7.39
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 7.31
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 7.27
Genome wide mapping of polyadenylation sites in proliferating and contact-inhibited cells and cells with knockdown of cleavage and polyadenylation factors 7.27
The evolution of N6-methyladenosine in primates 7.26
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 7.24
Genome-wide chromatin analysis of Ewing sarcoma 7.24
Vitamin C Promotes Apoptosis in Breast Cancer Cells by Increasing TRAIL Expression 7.23
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 7.21
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 7.12
GREB1, a novel target of Wnt signaling, promotes development of hepatoblastoma by suppressing TGFβ signaling 7.08
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 7.07
U1 snRNP telescripting regulates size-function stratified human genome 7.06
miR-450a acts as a tumor suppressor in ovarian cancer by readjusting energy metabolism 6.93
RNA expression analysis of neuroblastoma cell lines treated with epigenetic drugs 6.92
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation, modulates translation and spliceosomal processes 6.89
Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear RNA 6.85
A transcriptome-wide divergence in protein translation scales with LIN28B expression 6.79
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 6.77
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 6.77
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 6.76
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 6.76
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  6.7
Osteogenic programming of adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the Polycomb protein EZH2 6.68
Tracing Enhancer Networks using Epigenetic Traits (TENET) 6.66
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 6.62
Disruption of the exocyst induces podocyte loss and dysfunction 6.61
A global identification of PUM1 and PUM2 mRNA targets and their protein cofactors in human seminoma TCam-2 cells 6.61
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 6.56
The SUMO Pathway as a Therapeutic Option in Pancreatic Cancer 6.54
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 6.52
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 6.52
Differentiation enhances Zika virus infection in neuronal brain cells 6.43
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 6.43
HEK293 TFAM Knockout Expression Study 6.36
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer [RNA-Seq] 6.24
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer 6.24
Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function 6.23
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 6.22
Effect of drugs on transcriptomic profiles 6.21
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues (sequencing) 6.21
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues 6.21
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 6.19
Knockdown of ADNP in HCT116 colon cancer cells 6.19
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 6.19
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 6.19
Developmental stage specific chromosome architecture in human erythroid cells 6.18
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 6.18
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with tcons_00001221 shRNA or control shRNA 6.18
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 6.16
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation 6.06
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 6.02
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1 6.01
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 6.01
Trans-differentiation of human adult peripheral blood T cells into neurons 5.99
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 5.97
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 5.97
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 5.94
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 5.94
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 5.89
Gene expression in PANC1 cells treated with Rakicidin 5.87
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 5.85
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance 5.85
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq) 5.85
3’ Uridylation Expands miRNA Target Repertoire 5.85
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 5.84
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 5.8
Functional role of SLIT2 and ROBO1 in trophoblasts 5.79
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 5.77
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy 5.75
Complementary Post Transcriptional Regulatory Information is Detected by PUNCH-P and Ribosome Profiling 5.74
Non-transmissible measles virus vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells 5.73
Identification of Sin3B regulated genes during quiescence 5.72
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 5.71
Transcriptome sequencing of K-562 cells 5.6
Wnt addiction of genetically defined cancers reversed by PORCN inhibition 5.55
Gene expression analysis of dengue-infected cells 5.53
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 5.52
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 5.52
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 5.52
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 5.5
Global Transcriptional analysis of human spinal cord and neocortical neuroepithelial stem (NES) cells 5.48
Hypoxic regulation of transcription in HUVEC is mediated by EPAS1 5.46
Region-specific Innate Antiviral Responses of the Human Epididymis 5.41
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 5.4
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 5.39
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 5.32
Nuclear Actin Regulates Inducible Transcription by Enhancing RNA Polymerase II Clustering 5.32
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 5.28
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 5.28
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 5.28
Zika infected neural stem cells 5.27
Transcriptome analysis of Zika infected neural stem cells 5.27
Translocation of dense granule effectors across the parasitophorous vacuole membrane in Toxoplasma-infected cells requires the activity of ROP17, a rhoptry protein kinase 5.27
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 5.24
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 5.19
High-efficiency RNA-based reprogramming of human primary fibroblasts 5.19
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 5.15
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 5.15
Spliceosomal disruption of the non-canonical BAF complex in cancer 5.1
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 5.09
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 5.07
Transcription control by the ENL YEATS domain in acute leukemia 5.07
RNA sequencing of primary human platelets and in vitro cell lines 5.06
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 5.05
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 5.05
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 5.0
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 4.98
Conservative alteration of chromosomal expression pattern across human solid tumor types 4.97
Changes in CD34 and Erythroid Progenitor Transcriptome After RUNX3 Kock-down 4.9
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 4.9
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 4.9
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer 4.87
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer (RNA-seq) 4.87
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 4.87
Illumina Total RNA-seq in HeLa 4.86
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 4.86
RNA-seq of resting and activated CD4+ T cells +-JQ1 4.84
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 4.83
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 4.83
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 4.76
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq] 4.75
UV_24h_GRO-Seq 4.69
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 4.67
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 4.65
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 4.64
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 4.64
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 4.63
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 4.6
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 4.57
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 4.57
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. 4.56
Uridylation-mediated RNA quality control pathway in mammalian cytoplasm [RNA-Seq] 4.56
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 4.56
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 4.56
Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans. 4.48
RNA-seq profile of expanded human ST2-transduced Tregs cultured with IL-2 and TCR in the presence or absence of IL-33 4.45
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 4.43
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 4.43
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 4.4
Gene induction by the USP6 oncogene in response to interferon 4.34
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 4.33
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 4.32
Human cell line and subcutaneous tumor 4.31
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 4.3
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 4.3
Identification of global XBP1s target gene expression in human prostate cancer cells 4.28
Next generation sequencing of small RNAs isolated from exosomes in human semen 4.27
SNHG5 siRNA knock down in HCT116 cells 4.27
Epigenetic reprogramming of melanoma cells by vitamin C treatment 4.26
RNA-seq analysis of differentiating human erythroblasts 4.26
Total RNA sequencing of prospective axial stem cell cultures derived from human pluripotant stem cells 4.24
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer [RNA-seq] 4.21
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer 4.21
mRNA differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 4.17
Differential expression in LNCaP cells expressing the wild-type androgen receptor (AR-WT) or the ligand-independent AR-V7 splice variant 4.17
MOV10 Is a 5' to 3' RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3'UTRs 4.15
MOV10 Is a 5' to 3' RNA Helicase Contributing to UPF1 mRNA Target Degradation by Translocation along 3'UTRs (expression) 4.15
FMR1 reactivating treatments in Fragile X iPSC-derived neural progenitors in-vitro and in-vivo 4.09
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 4.07
The Genetic Landscape of Diamond-Blackfan Anemia 4.04
High-throughput RNA sequencing on circular RNA profiles of human pancreatic cancer cell lines and gemcitabine resistant pancreatic cancer cell lines. 4.03
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 4.01
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 4.01
Gene expression in GBM with Cav3.2 inhibition 3.99
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 3.96
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 3.96
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 3.96
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 3.95
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 3.94
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 3.93
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 3.93
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 3.92
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 3.91
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 3.9
Human Treg NaCl stimulation 3.86
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 3.86
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 3.85
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 3.85
RNA-seq of hiPSCs-derived NPCs from 3 pairs of dizygotic discordant twins for Congenital Zika syndrome 3.83
RNASeq of 4SU labelled nascent RNA in MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 3.82
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 3.82
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition [CAGE] 3.77
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition 3.77
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 3.77
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 3.74
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 3.71
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 3.67
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 3.63
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 3.62
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 3.61
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates 3.61
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates (part 4) 3.61
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 3.59
Evolving Spindlin1 Small Molecule Inhibitors Using Protein Microarrays 3.55
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 3.54
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 3.49
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 3.49
RNA sequencing with KSHV infection and enrichment for circular RNAs 3.45
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 3.41
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 3.37
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 3.33
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 3.33
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 3.33
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal 3.32
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal [RNA-Seq] 3.32
RNA-seq of human foreskin fibroblast cells lacking RB, p130, and p107 treated with doxorubicin. 3.27
Determining mRNA half-lives on a transcriptome-wide scale 3.24
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 3.22
High-resolution comparative analysis of great ape genomes 3.16
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 3.16
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 3.16
RNA-seq of RKO cells with cTAZ KO or putback 3.16
Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs 3.1
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of AIM2. 3.09
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 3.02
Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. 3.02
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer 3.01
Myeloid-derived suppressor cells facilitie invasion and metastasis of papillary thyroid cancer cells by repressing miR-486-3p 2.97
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 2.96
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 2.96
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 2.93
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 2.9
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 2.89
Searching for target genes of miR-508/509/506/514 in HCT116 cells 2.88
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits 2.84
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits [mRNA-Seq] 2.84
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 2.83
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock [RNA-Seq] 2.82
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock 2.82
Characterization of Type I Interferon pathway during Hepatic Differentiation of Human Pluripotent Stem Cells and hepatitis C virus infection 2.75
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 2.73
METTL3 and WTAP 2.7
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 2.7
In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity 2.69
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 2.68
Transcriptomic profile of T cell acute lymphoblastic leukemia (T-ALL) cell from patients in CHCQMU 2.65
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 2.65
Loss of CREBBP results in gene expression repression in lymphoma cells 2.65
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 [RNA-seq] 2.59
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 2.59
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 2.56
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells 2.56
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells [RNA-seq] 2.56
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 2.56
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 2.54
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo 2.51
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo [RNA-seq] 2.51
HBEC-shp53-PCHD7 2.46
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 2.44
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 2.43
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction [III] 2.4
A20 regulates canonical wnt-signaling through an interaction with RIPK4 2.26
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 2.24
FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA 2.21
Gene expression profile in FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA using RNA-seq. 2.21
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 2.2
Next Generation Sequencing upon siRNA-mediated knockdown of DRAIC in MCF-7 cells. 2.15
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 2.15
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 2.15
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 2.07
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 2.05
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 2.05
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 2.05
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 2.03
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 2.03
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 1.96
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 1.94
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 1.94
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 1.92
CDK12 mediated transcriptional regulation in U2OS cells 1.92
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 1.91
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 1.88
Transcriptomic profiling of O-GlcNAcylated mRNA-protein complexes by using OG-CLAP in HeLa cells. 1.88
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 1.85
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 1.85
Genome-wide mapping of TEL-AML1 targets in acute leukemia 1.85
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 1.85
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 1.83
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 1.83
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 1.83
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 1.79
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 1.69
Discovering human diabetes-risk gene function with genetics and physiological assays 1.68
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 1.62
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 1.62
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 1.59
RNA-seq analysis of PRMT5-regulated genes in irradiated/non-irradiated LNCaP cells 1.58
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 1.53
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 1.51
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 1.43
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 1.42
Evaluation of the effectiveness of semen collection and sperm purification methods for spermatozoa transcript profiling 1.41
High-throughput sequencing of PROMPT-enriched samples. 1.41
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 1.41
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 1.4
Widespread backtracking by RNA pol II is a major effector of gene activation, 5’ pause release, termination and transcription elongation rate 1.37
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.37
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 1.34
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 1.3
K562 polyA RNA-Seq 1.3
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 1.28
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 1.28
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 1.26
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line 1.23
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line [RNA-Seq] 1.23
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 1.23
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 1.23
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 1.2
MicroRNA-125a-5p overexpression in human macrophages 1.13
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 1.09
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability] 1.05
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 1.05
Time series total RNA sequencing of a differentiation of human embryonic stem cells towards trophoblast lineage 1.01
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 0.98
Effect of PDZ domain binding Kinase inhibition using TOPK-32 (called PBKi) on C4-2 cell transcriptome 0.95
mRNA recovered upon RNF219 IP. [RNA-IP] 0.95
Human Treg IL-12 stimulation 0.89
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 0.88
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer 0.88
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer [RNA-seq] 0.88
Small-molecule targeting of brachyury transcription factor addiction in chordoma 0.88
Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes 0.86
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 0.86
Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics 0.81
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 0.78
single cell RNA-seq from GM12878 (ENCSR673UIY) 0.75
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 0.67
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 0.65
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.61
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.61
Myc activation coordinates gene transcription and protein translation responses 0.6
RNA-seq data 0.59
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 0.57
Apoptosis enhancing drugs overcome innate platinum resistance in CA125 negative tumor initiating populations of high grade serous ovarian cancer 0.55
Interphase condensins regulate ligand-depedent enhancer activation (GRO-seq) 0.54
Interphase condensins regulate ligand-depedent enhancer activation 0.54
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 0.54
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 0.47
A single cell reference map for human blood and tissue T cell activation 0.45
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 0.44
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.43
4sUDRB-seq: measuring transcription elongation and initiation genomewide 0.42
JAG1 Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium 0.42
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.4
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.39
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.39
RNA-seq analysis reveals endogenous aryl hydrocarbon receptor regulation is highly associated with eicosanoid synthesis and tumor necrosis factor activity in MCF-7 cancer cells 0.28
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 0.26
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.23
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 0.23
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 0.23
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.23
mTORC1 balances cellular amino acid supply with demand for protein synthesis through post-transcriptional control of ATF4 0.22
Antioxidant metabolism in activated CD8+ T cells regulates stem-like human memory T cell formation and anti-tumor immunity 0.21
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis 0.19
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells 0.14
Single cell RNA-seq resolves lineage-specific activation dynamics of human blood and tissue T cells 0.13
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 0.1
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 0.1
Identification of downstream genes regulated by YAP1 through knockdown and overexpression of YAP1 in U251 cell with a stably expression of mutant APP 0.09
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.08
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 0.07
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 0.05
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.01
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.01


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