Gene Query: POLR3A

Dataset Description Geneva Score
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 38.35
Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis . 27.3
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 23.05
Quantitative Analysis of negative control and overexpression-TRIB1 in PC3 and DU145 Transcriptomes 20.88
MYCi975 regulates MYC target genes 19.24
RNA-seq Analysis of Castration-Resistant Prostate Cancer With Knock-down of E2F1 18.04
RNA transcriptome analysis during HSV-1 infection 17.49
RNA-seq analyses of human prostate cancer cells 16.74
Genome-wide CRISPR-Cas9 screen identifies SLC1A3 as a key contributor to L-asparaginase Resistance in Solid tumors 16.53
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HET] 16.44
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 15.87
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 14.92
Next Generation Sequencing upon siRNA-mediated knockdown of DRAIC in MCF-7 cells. 14.78
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 14.71
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 14.62
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 14.11
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 13.73
RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures 13.7
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 13.5
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 13.5
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 13.1
Defining a microRNA-mRNA targetome for calcineurin inhibitor induced nephrotoxicity 13.0
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 12.94
A transcriptome-wide divergence in protein translation scales with LIN28B expression 12.9
Co-regulation of splicing by Rbfox1 and hnRNP M 12.04
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 12.04
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways 11.91
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 11.85
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer 11.72
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer [RNA-seq] 11.72
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 11.64
3’ Uridylation Expands miRNA Target Repertoire 11.51
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived SPINK1 11.18
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia [shRNA] 11.16
miR-450a acts as a tumor suppressor in ovarian cancer by readjusting energy metabolism 11.1
RNA sequencing of mechanically strained NHEKs and control NHEKs 10.86
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 10.85
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 10.34
Ribosomal footprinting of MDA-Parental and MDA-LM2 10.25
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 10.14
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 10.14
Transcriptomic analyssis following EHMT1/2 inhibition 10.01
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 9.99
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 9.89
RNAseq Analysis in glioblastoma cells treated with Mepazine 9.82
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 9.57
FGF2 induces migration of human bone marrow stromal cells by increasing core-fucosylations on N-glycans of integrins 9.55
Transcription differences in DLBCL cell lines U2932, DOHH2 on treatment with TK compound compared to DMSO 9.52
Genetic-to-epigenetic Therapy for Pancreatic Cancer 9.45
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 9.38
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 9.01
Leukodystrophy-associated POLR3A mutations down-regulate the RNA polymerase III transcript and important regulatory RNA BC200 8.96
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 8.83
Atheroprotective flow alters EZH2/H3K27me3 dependent transcriptional profile in human endothelial cells 8.72
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network 8.72
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2 [RNA-seq] 8.72
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 8.58
Characterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer 8.57
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 8.55
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 8.55
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 8.46
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 8.46
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 8.46
Multiple roles for Grainyheadlike transcription factors in the establishment and maintenance of human mucociliary airway epithelium 8.37
Messenger RNA profile analysis deciphers new Esrrb responsive genes in prostate cancer cells 8.36
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 8.36
Gene expression analysis of the impact of TDP-43 knockout in human cells. 8.34
U1 snRNP telescripting regulates size-function stratified human genome 8.33
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 8.21
Ribosomal footprinting of CN34-Parental and CN34-LM1a 7.94
Gene expression in PANC1 cells treated with Rakicidin 7.94
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 7.88
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 7.88
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 7.83
EWSR1 influences alternative splicing through direct and indirect mechanisms 7.8
Transcriptomic analysis of human coronary artery endothelial cells stimulated with TNF-alpha in the presence and absence of ACSL3 siRNA 7.75
mRNA-sequencing of 293T-no dice transfected with miR-16, miR-214, or KSHV-miR-K6-5p 7.75
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 7.59
A Unique Epigenomic Landscape Defines Human Erythropoiesis 7.59
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 7.55
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 7.55
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 7.54
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 7.54
HNRNPM-regulated splicing dependencies in prostate cancer [RNA-Seq] 7.54
HNRNPM-regulated splicing dependencies in prostate cancer 7.54
RNA-sequencing WT vs SOCS3 knockout Glioblastoma stem-cells 7.53
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 7.48
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 7.47
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 7.41
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 7.36
Chemotherapeutic drugs inhibiting Topoisomerase 1 activity inhibit TNF-induced inflammatory gene expression 7.27
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 7.25
Genome wide miR-191 target profile determined by RIP and gene expression profiling 7.23
miR-191 regulates human cell proliferation and directly targets multiple oncogenes [seq] 7.23
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 7.17
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 7.17
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 7.16
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 7.03
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 7.03
Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases 6.97
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 6.96
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 6.96
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 6.84
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 6.83
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 6.81
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1 6.74
Next Generation Sequencing Facilitates Quantitative Analysis of colorectal cancer cells transfected with NC siRNA or RPL9 siRNA 6.72
Alternative splicing regulated by QKI and RBFOX1 promotes the mesenchymal cell state in breast cancer 6.71
RNA-sequencing in immortalized human mammary epithelial cells 6.71
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 6.71
Maturation of human iNSCs 6.7
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 6.65
Sequencing-based analyses characterize a tumor suppressive role of mir-1271 repressed by DNA hypermethylation in gastric cancer 6.65
MeRIP sequencing reveals angiogenic properties of vascular endothelial cells 6.63
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 6.62
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 6.62
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 6.59
Function of HNRNPC in breast cancer cells by controlling the dsRNA-induced interferon response 6.58
Genome-wide analysis of the Integrator complex (HTS) 6.58
Genome-wide analysis of the Integrator complex 6.58
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 6.57
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 6.57
RNA-seq analysis of control and Myc-induced U2OS cells 6.56
The stress granule transcriptome reveals principles of mRNA accumulation in stress granules. 6.52
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 6.47
IMP3 regulated gene expression in breast cancer cells 6.45
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 6.42
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 6.42
Human Adipocytes Regulate Gene Expression in Triple-negative Breast Cancer Assessed by NGS Sequencing 6.36
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 6.34
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 6.34
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 6.33
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 6.32
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq 2] 6.31
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 6.3
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 6.3
Global analysis of alternative splicing regulated by RBM10 6.28
Transcriptome Analysis of CircMRPS35 mediated mRNA expression profiles 6.25
PNET animal model: new insights (II) 6.24
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 6.24
R430: A potent inbibitor of DNA and RNA viruses 6.23
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [ChrRNA-seq] 6.22
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 6.2
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 6.16
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 6.08
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 6.07
RNA-seq after siRNA targeting DDX24 applied to iHUVECs cell lines 6.06
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 6.02
The effect of REST and its alternatively spliced transcript, REST-003, on breast cancer invasiveness 6.01
Rna-seq transcriptome data for insulin-GFP+ cells differentiated from NEUROD1 knock out and NEUROD1+/+ control human embryonic stem cells. 6.0
NEUROD1 dependent gene regulation in murine pancreatic endocrine cells and human stem cell derived insulin producing cells 6.0
RNA-seq analysis of RALD iPSCs after in vitro differentiation 5.97
KMT2C medaites the estrogen dependence of breast cancer through regulation of ERα enhancer function 5.92
TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality 5.86
Proliferation pause as an early blockade of human cellular reprogramming toward pluripotency [RNA-seq analysis] 5.82
Trans-chromosomal regulation by a novel lincRNA required for adipogenesis that escapes X-chromosome inactivation 5.81
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation 5.79
Bladder cancer associated mutations in RXRA activate peroxisome proliferator-activated receptors 5.79
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 5.78
Chromatin-informed inference of transcriptional programs in gynecologic cancers 5.74
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 5.74
Endothelial gene expression analysis 5.73
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 5.73
Identification of HOXB13 target genes responsive to BET inhibitors 5.73
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 5.71
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 5.69
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 5.66
Effect of estrogen (E2) treatment on the C4-12 relative to the MCF7 cells 5.65
MicroRNA targetome analysis during HCMV infection 5.65
XPO1 inhibition antagonizes MCL via nuclear retention of IkB: Selinexor demonstrates antitumor activities in both ibr-sensitive and ibr-resistant tumor cells 5.65
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 5.63
RNA-seq analysis of control and NRDE2-depleted breast cancer cells 5.62
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 5.59
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 5.59
Investigsting the role of NF-ĸB p50 S80 phosphorylation in regulating TNFα-induced transcription in HEK293T cells 5.59
Quantitative comparison between cellular mRNAs and exosomal mRNAs in human iPSC-derived motor neurons 5.58
Seletive inhibition of CDK9 in DLBCL cell lines 5.55
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 5.55
CHD1 regulates cell fate determination by activation of differentiation-induced genes 5.54
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 5.52
Single-cell expression profiling reveals new roles for G-protein-coupled receptors in the regulation of Th17 pathogenicity 5.52
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 5.48
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 5.45
Differentially expressed vascular development genes for iPSC-ECs from CDI 5.44
TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells [RNA-seq] 5.43
TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells 5.43
A sister of NANOG regulates genes expressed in pre-implantation human development 5.43
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 5.42
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 5.41
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 5.39
Inhibition of the Aryl Hydrocarbon Receptor - Polyamine Biosynthesis Axis Suppresses Multiple Myeloma and prostate cancer progression 5.39
Effect of drugs on transcriptomic profiles 5.33
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 5.31
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells 5.3
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 5.29
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 5.26
Cell-specific expression and function patterns of microRNA-150-5p in liver fibrogenesis 5.26
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 5.25
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  5.23
The DPYSL2 gene connects mTOR and schizophrenia 5.23
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 5.22
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 5.22
MYC dependent mRNA translation shapes gene expression and cell biology 5.18
Cajal bodies are linked to genome conformation 5.16
Cajal bodies are linked to genome conformation [RNA-Seq] 5.16
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 5.14
N6-methyladenine DNA Modification in Glioblastoma 5.14
Genome-wide transcriptome profiling of NEDD9-regulated genes using RNA-seq 5.13
Transcriptome changes due to nuclear penetration of cancer extracellular vesicles 5.12
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 5.11
Endothelial-AGO1-knockout (EC-AGO1-KO) mice and wild-type (WT) littermates 5.1
RNA Seq of HMVEC under hypoxia 5.1
Codon usage optimization in pluripotent embryonic stem cells [RNA-seq] 5.07
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 5.06
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 5.04
FOXP1 orchestration of ASD-relevant signaling pathways. 5.04
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 5.02
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 5.02
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 4.98
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner 4.97
EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC 4.94
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 4.92
Non-transmissible measles virus vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells 4.91
Modulation of nonsense-mediated decay by rapamycin 4.86
Genome-wide transcriptional response to random aneuploidy in human cells 4.85
Chromatin landscape of human visceral and subcutaneous adipocytes 4.84
Role of XRN2 ribonucleolytic activity in RNA metabolism 4.81
RNA-seq analysis of A498 cell line treated with siSETD2 or si-NC 4.8
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells 4.77
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells [RNA-seq] 4.77
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 4.76
Early transcriptome profiling of microRNA-mediated neuronal reprogramming [RNA-seq timecourse] 4.75
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 4.74
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 4.74
Genome-wide MAF1-dependent regulation of RNA polymerase III transcription [RNA-Seq] 4.74
Genome-wide MAF1-dependent regulation of RNA polymerase III transcription 4.74
H3K27ac ChIP-Seq and mRNA-Seq analysis of five human B-lymphoblastoid cell lines (LCLs) prepared from the same healthy male individual (CEPH/UTAH). 4.72
4.7
Targets of CDK12 on ZR-75-30 breast cancer cells (RNA-seq) 4.7
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 4.7
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 4.69
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 4.68
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 4.68
Plasma cell mitochondrial pyruvate import controls the duration of humoral immunity. 4.65
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 4.63
Transcription elongation factors are in vivo-specific cancer dependencies in glioma 4.62
RNA-seq Profiles in Transcription elongation factors are in vivo-specific cancer dependencies in glioma 4.62
Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies 4.59
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 4.59
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 4.59
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 4.56
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 4.54
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 4.52
Mapping interactions for the TNIP2 hub protein 4.51
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 4.5
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 4.5
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 4.5
Proteolytic cleavage by taspase1 and the regulation of the stability of MLL1 4.47
miRNAs affected by antagomiR-17 treatment 4.44
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 4.43
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 4.4
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 4.37
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 4.35
4sUDRB-seq: measuring transcription elongation and initiation genomewide 4.31
Identification of an IL-1-induced gene expression pattern in AR+ PCa cells that mimics the molecular phenotype of AR- PCa cells 4.3
ERK potentiates transactivation and oncogenic function of ERG by phosphorylation induced dissociation of PRC2 complex 4.27
Capturing the Interactome of Newly Transcribed RNA 4.27
Capturing the Interactome of Newly Transcribed RNA (RICK) 4.27
Widespread backtracking by RNA pol II is a major effector of gene activation, 5’ pause release, termination and transcription elongation rate 4.26
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 4.2
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 4.2
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 4.18
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 4.18
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 4.17
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 4.17
UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons 4.12
KLF6-dependent transcription in renal cancer cells 4.09
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation 4.08
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 4.06
UV_24h_GRO-Seq 4.04
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 3.99
Knockdown of ADNP in HCT116 colon cancer cells 3.99
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 3.97
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 3.97
Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist 3.95
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 3.95
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer 3.95
Effect of CHKA knockdown on C4-2 cell transcriptome 3.94
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 3.9
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 3.9
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 3.9
Transcriptional response of human endocervical epithelial A2EN cells to infection with wild-type or CpoS-deficient Chlamydia trachomatis L2/434/Bu 3.89
Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap 3.87
Analysis of active enhancers and direct androgen receptor target genes in VCaP prostate cancer cells 3.84
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 3.83
The SUMO Pathway as a Therapeutic Option in Pancreatic Cancer 3.83
Effect of PBK knockdown on C4-2 cell transcriptome 3.75
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 3.74
Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV. 3.72
Aneuploidy triggers an immune response 3.69
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation 3.67
Cooperation of GRSF1 and the mitochondrial degradosome (hSuv3-PNPase complex) in degradation of mitochondrial RNA 3.6
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 3.59
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 3.59
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal 3.57
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal [RNA-Seq] 3.57
Gene expression in GBM with Cav3.2 inhibition 3.57
Mutational landscape of splicing genes and functional consequences across 33 cancer types 3.56
SETDB1 compacts the inactive X chromosome in part through silencing an enhancer in the IL1RAPL1 gene 3.56
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 3.55
Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance  3.54
Genome-wide discovery of human splicing branchpoints 3.49
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 3.48
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 3.43
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 3.43
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites 3.42
Replicative senescence is associated with nuclear reorganization and DNA methylation at specific transcription factor binding sites (RNA-seq) 3.42
RNA-seq of naive and primed ES cells 3.42
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 3.36
RNA-seq analysis of the role of HBO1 (KAT7/MYST2) in the ovarian cancer cell line UWB1.289. 3.31
Transcriptional dependencies in diffuse intrinsic pontine glioma 3.29
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 3.29
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 3.28
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 3.27
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP 3.25
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 3.2
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 3.2
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer 3.17
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer [RNA-seq] 3.17
Gene Expression Profiling of Cutaneous CD30+ Lymphoproliferative Disorders by RNA-seq 3.1
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 [RNA-Seq] 3.09
ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 3.09
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 3.07
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates (part 4) 3.07
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates 3.07
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 3.06
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 3.04
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 3.02
RNA-seq of tumor cells following angiopellosis extravasation 3.01
PRDM1 inhibits proliferation of human colon cancer organoids 2.99
METTL3 and WTAP 2.98
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 2.96
Functional role of CPPED1 in trophoblasts. 2.93
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 2.91
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 2.9
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 2.88
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 2.86
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 2.86
Long non-coding RNA TYKRIL controls pericyte function and survival in the cardiovascular and central nervous system through regulation of p53 activity and PDGFRß expression 2.84
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 2.83
Gene expression profiles of BxPC-3, MiaPaCa-2 and PANC-1 cell lines treated with DMSO and THZ1 respectively 2.8
Transcriptome profiling of HepG2 cells upon treatment of the menin-MLL inhibitor MI-503 or DMSO 2.78
Subcellular RNA fractions of HSV-1 infected primary human fibroblasts 2.75
Transcriptome analysis upon C6orf203 silencing 2.74
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 2.73
Inhibition of ERG Activity in Patient Derived Prostate Cancer Xenografts using the Small Molecule Inhibitor YK-4-279 2.73
Single cell transcriptomics analysis of induced pluripotent stem cell-derived cortical neurons reveals frequent dual layer identity 2.73
AUF-1 affected genes in human skin cells 2.72
Identification of a LIF-responsive replication-competent human β cell 2.69
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 2.67
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 2.67
Study of dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest 2.64
CXCR4 is a host factor that regulates Plasmodium development in hepatocytes 2.61
RNA-seq of RKO cells with cTAZ KO or putback 2.59
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 2.59
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 2.58
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 2.58
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 2.55
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 2.55
ETV7 and interferon response 2.5
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 2.5
Toxoplasma gondii infection of human retinal pigment epithelial cells 2.5
Transcriptomic Analysis Of circRNAs/miRNAs/mRNAs upon Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection 2.49
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 2.49
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 2.47
Transcriptional profile of human STAT1-/- fibroblasts expressing LY6E or empty control vector 2.47
Gene expression profile in breast cancer cell lines using RNA sequencing 2.45
Functional significance of the HIV-1 Tat signature amino acid residues 2.44
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 2.44
RNA-SEQ assay for wild type and CRISPR induced endoglin knockout human pulmonary artery smooth muscle cells (PASMC) 2.32
A single-cell atlas of the human cortex reveals drivers of transcriptional changes in Alzheimer’s disease in specific cell subpopulations 2.29
Meta-organization of Translation Centers Revealed by Proximity Mapping of Endoplasmic Reticulum Ribosome Interactors 2.27
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 2.24
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 2.2
Comparative Analysis of Cas9 Activators Across Multiple Species 2.2
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 2.2
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 2.2
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 2.2
Expression profiling by RNA-Seq of breast cancer samples from patients in walnut-consuming and control groups 2.19
Identification of miR-100 and miR-125b targets by AGO2 RIP-seq and RNA-seq after ectopic expression of miR-100 or miR-125b and evaluation of the TGFb expression signature in PANC-1 cells by RNA-seq 2.07
microRNA-seq and RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 2.06
RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 2.06
Hypoxic regulation of gene expression in HUVEC is dominated by EPAS1 2.03
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 2.01
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing (Total RNA sequencing) 1.96
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis [RNA-Seq] 1.96
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis 1.96
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 1.88
RNA seq with AML (NB4) cells upon FTO inhibition 1.86
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II] 1.86
BRG1 governs Glucocorticoid Receptor interactions with chromatin and pioneer factors across the genome 1.72
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 1.71
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 1.68
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 1.68
Folate modulation induces chromosomal instability and higher proliferation of immortalized human keratinocytes 1.66
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 1.66
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 1.6
RNA binding protein CPEB1 remodels host and viral RNA landscapes [RNA-Seq] 1.59
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 1.52
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 1.52
Oxaliplatin resistance is enhanced by saracatinib via upregulation of ABCG1 and Wnt/β-catenin signaling in hepatocellular carcinoma 1.5
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 1.48
RNA-Seq analysis of prostate cancer cell line LNCaP treated with vehicle, androgen, androgen and IMTPPE, androgen and JJ-(+)-450, androgen and JJ-(-)450, androgen and enzalutamide 1.45
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 1.43
Time series total RNA sequencing of a differentiation of human embryonic stem cells towards trophoblast lineage 1.42
ADAR1-editing of cellular and measles virus-derived duplex RNA 1.37
ADAR1-editing in HeLa, p150-KO and ADAR1-KO transcriptomes 1.37
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 1.36
Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes 1.34
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 1.34
Myc activation coordinates gene transcription and protein translation responses 1.33
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 1.33
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 1.33
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 1.33
A compendium of promoter-centered long-range chromatin interactions in diverse human tissues and cell types 1.3
single cell RNA-seq from GM12878 (ENCSR673UIY) 1.29
A MYC/GCN2/eIF2alpha negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer 1.27
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 1.18
Wnt5a and its downstream transcription factor Stat3 are therapeutic targets for diffuse intrinsic pontine gliomas 1.18
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 1.17
Gene expression of thyroid cancer cell lines 1.15
Molecular Criteria for Defining the Naive Human Pluripotent State 1.1
Effect of nuclear IL-33 on gene expression 1.1
Gene expression for surgically treated pancreatic cancer after one neoadjuvant vaccine dose 1.09
UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation 1.08
Cell cycle dynamics of human pluripotent stem cells primed for differentiation 1.06
Immune Checkpoint Regulation of Pulmonary Fibrosis [bulk RNA-seq] 1.03
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [H1 RNA-seq] 1.01
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 0.93
KAP1 regulates ERVs in differentiated human cells and contributes to innate immune control 0.91
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 0.91
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] 0.9
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 0.9
Downregulation of LATS kinases alters p53 to promote cell migration 0.88
Transposon-based construction of strand-specific RNA-seq libraries 0.88
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 0.83
Cellular recruitment by podocyte-derived pro-migratory factors in assembly of the human renal filter 0.78
RNA-seq of IL-4 stimulated human keratinocytes 0.78
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 0.75
RNA-Seq of SLNCR1 over-expression in the melanoma cell line A375 0.71
O-glcnAc reprograms cellular energetics 0.68
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers 0.63
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers (RNA-Seq) 0.63
Iron response of HepG2 cells 0.61
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 0.6
A20 regulates canonical wnt-signaling through an interaction with RIPK4 0.56
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 0.56
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 0.56
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (scRNA-Seq) 0.54
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 0.54
Ribosomal protein RPL26 is the principal target of UFMylation 0.52
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers [RNA-Seq] 0.52
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers 0.52
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.47
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.45
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk 0.44
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk [RNA-seq] 0.44
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 0.43
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 0.43
Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements 0.39
Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome 0.38
ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex 0.38
UMI-count modeling and differential expression analysis for single-cell RNA sequencing 0.36
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.35
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 0.33
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells 0.33
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 0.29
Genome-Wide Specificity of DNA-Binding, Gene Regulation, and Chromatin Remodeling by TALE- and CRISPR/Cas9-Based Transcription Factors 0.21
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 0.21
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 0.21
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 0.21
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 0.21
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.2
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.2
single cell RNA-seq from Purkinje cell (ENCSR888LYA) 0.19
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.19
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 0.18
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.15
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 0.15
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 0.15
Gene expression changes due to PARP knockdown in human cells 0.13
RNA-seq of HUVEC ± shRNA knockdown of SENCR 0.12
Next Generation Sequencing of Lung Primary Fibroblast Responding to Eosinophil-Degranulation Products 0.1
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  0.09
hsa-miR-503, hsa-miR-103, and hsa-miR-494 genome wide target profiles [RNA-Seq and RIP-Seq] 0.08
Genome-wide hsa-miR-503, hsa-miR-103, and hsa-miR-494 target profiles 0.08
Function and hormonal regulation of GATA3 in human first trimester placentation 0.08
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 0.07
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.04
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.02


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