Gene Query: PRIM1

Dataset Description Geneva Score
Mechanosensitive ion channel regulates tissue stiffening to promote glioma aggression 36.67
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 32.18
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 31.58
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 29.15
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 23.97
The Human Testis Cell Atlas via Single-cell RNA-seq (Healthy men scRNA-seq data set) 22.23
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 21.64
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 17.4
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 16.59
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 16.41
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 16.14
Transcription control by the ENL YEATS domain in acute leukemia 15.41
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 15.41
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 15.32
Identification of global regulators of T-helper cell lineage specification 15.12
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 15.12
LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene 14.5
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 13.49
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 13.34
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 13.34
LNCaP treated with iBET 12.87
Targeting MTHFD2 in Acute Myeloid Leukemia 12.85
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 12.78
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 12.78
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 12.57
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions 12.05
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 12.05
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 12.04
Neonatal and adult human testis defined at the single-cell level 11.86
transcriptomic profiling of HEK293 cells upon individual knockdown of the splicing factors RBM17, U2SURP or CHERP 11.65
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 11.58
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 11.39
In situ CAPTURE of chromatin interactions by biotinylated dCas9 11.38
RNA-seq transcriptonal profiling in human K562 cells with or without dCas9 and sgRNAs 11.38
IRF1 regulates IFN dependent and independent gene expression 11.22
Peptidomimetic blockade of MYB in acute myeloid leukemia 11.15
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 11.15
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 10.96
Hijacking of stress response machinery by oncogenes in acute leukaemia 10.96
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 10.66
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 10.61
Dtx3L and Androgen Signaling in Prostate Cancer 10.6
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival 10.58
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival [RNA-Seq] 10.58
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 10.47
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 10.36
HEK293 TFAM Knockout Expression Study 10.35
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 10.32
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [cPDS-RNA-seq] 10.14
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 9.94
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 9.94
ETV7 and interferon response 9.94
Oncogenic MYC induces a dependency on the spliceosome in human cancer 9.92
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 9.9
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 9.9
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 9.9
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 9.69
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 9.69
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 9.5
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 9.32
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 9.31
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 9.26
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 9.22
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 9.2
microRNA suppresses prostate cancer stem cells and metastasis by inhibiting a cohort of pro-metastasis targets including CD44, Rho GTPases and EZH2 9.09
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 8.96
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 8.88
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 8.86
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 8.86
Biological effect of chronic mistranslation in mammalian cells 8.83
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 8.83
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 8.83
HNRNPM-regulated splicing dependencies in prostate cancer [RNA-Seq] 8.76
HNRNPM-regulated splicing dependencies in prostate cancer 8.76
p53 activity results in DNA replication fork processivity 8.72
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 8.69
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 8.63
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 8.63
A map of gene expression in neutrophil-like cell lines 8.5
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 8.46
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 8.4
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 8.2
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 8.01
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 7.79
SRSF2 mutations impair hematopoiesis and alter exon recognition 7.79
Genome wide transcriptome analysis of palbociclib or GSK3326595 treated A375 cells [Palbociclib_GSK_RNASeq] 7.69
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 7.56
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 [RNA-seq] 7.53
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 7.53
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 7.52
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 7.52
Next Generation RNA Sequencing Analysis of AMPK Wild Type, AMPKα-KO and AMPKα1-2A U2OS cell Transcriptomes 7.47
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 7.39
Gene expression changes after depletion of Cyclin F and atypical E2Fs in HeLa cells. 7.39
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 7.39
Hierarchy of mono- and bi-allelic TP53 alterations in Multiple Myeloma cell fitness 7.37
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 7.35
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 7.33
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 7.28
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 7.27
Effect of CHKA knockdown on C4-2 cell transcriptome 7.21
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 7.19
Genome-wide analysis of the Integrator complex (HTS) 7.17
Genome-wide analysis of the Integrator complex 7.17
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 7.1
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 7.09
The X-linked DDX3X RNA helicase dictates translation re-programming and metastasis in melanoma 7.08
Identification of HOXB13 target genes responsive to BET inhibitors 7.08
XPO1 inhibition antagonizes MCL via nuclear retention of IkB: Selinexor demonstrates antitumor activities in both ibr-sensitive and ibr-resistant tumor cells 7.07
Gene induction by the USP6 oncogene in response to interferon 7.04
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 7.03
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 7.01
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 6.94
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 6.89
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 6.86
Alternative splicing of differentiated myeloid cell transcripts after infection by Anaplasma phagocytophilum impacts a selective group of cellular programs 6.82
RNA-seq of RKO cells with cTAZ KO or putback 6.77
Spliceosomal disruption of the non-canonical BAF complex in cancer 6.76
N6-methyladenine DNA Modification in Glioblastoma 6.71
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 6.71
Small molecule targets TMED9, promotes lysosomal degradation to reverse proteinopathy 6.68
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 6.66
Gene expression changes after LOC550643 silencing 6.64
LncRNA-GAS5 negative regulation of YAP-target genes expression 6.63
Overexpression and knockdown experiment for circCSNK1G3 6.56
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 6.56
MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway 6.55
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 6.52
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 6.48
RIG-I and MDA5 fRIP during KSHV lytic reactivation 6.47
Transcriptome profiling of Caki2 cells re-expressing Polybromo-1 (PBRM1) 6.46
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 6.42
Comprehensive comparative analysis of RNA sequencing methods for degraded or low input samples 6.39
High-efficiency RNA-based reprogramming of human primary fibroblasts 6.35
Identification of the O-GlcNAc-regulated alternative splicing events by performing RNA sequencing on HeLa cells with altered O-GlcNAc level. 6.34
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 6.34
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis [RNA-Seq] 6.34
Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis 6.34
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 6.28
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 6.25
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 6.24
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 6.22
RNA-seq of resting and activated CD4+ T cells +-JQ1 6.12
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 6.11
Proteotranscriptomic profiling of potential E6AP targets in prostate cancer cells 6.05
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 6.05
A Unique Epigenomic Landscape Defines Human Erythropoiesis 6.05
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 6.03
RNA seq comparison between scrambled and shGRP78 cells 5.97
Cancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor development 5.92
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 5.88
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells 5.87
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells [RNA-seq] 5.87
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 5.85
The pause-initiation limit restricts transcription activation in human cells 5.81
RNA-seq analysis to identify the genes regulated by p53-SET interplay 5.76
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network 5.76
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 5.71
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 5.69
RNA-seq analysis of differentiating human erythroblasts 5.66
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 5.66
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 5.65
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 5.65
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer [RNA-Seq] 5.58
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer 5.58
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 5.57
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 5.57
Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma engages the ER-stress response II 5.57
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 5.51
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 5.51
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 5.5
Cerebellar differentiation in Ataxia-Telangiectasia 5.5
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 5.48
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 5.48
TT-Seq captures the human transient transcriptome 5.46
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 5.46
SUV420H2 knockdown in PANC-1 5.39
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 5.33
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 5.33
Integrative classification of human coding and non-coding genes based on RNA metabolism profiles 5.3
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 5.27
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 5.27
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 5.26
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 5.26
Real-time observation of light-controlled transcription in living cells 5.26
Gene expression in PANC1 cells treated with Rakicidin 5.24
Genes altered in expression by Cisplatin treatment in lung cancer cell lines 5.23
Enriched retinal ganglion cells derived from human embryonic stem cells (RNA-seq) 5.21
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 5.21
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation 5.2
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 5.2
RNA-Seq of cKIT+ sorted cells from 16-16.5 week old fetal testes and ovaries and RNA-Seq of TRA-1-60+ H1 hESCs 5.18
RNAseq Study in CC-671 Treated Cal-51 Cells 5.18
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 5.17
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 5.13
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [RNA-Seq] 5.12
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 5.12
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation II 5.11
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 5.09
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 5.08
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 5.08
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 5.07
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 5.05
Generating Patterned Kidney Organoids for Studying Development and Diseases 5.0
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (RNA-seq dataset) 4.98
Single-cell RNA Sequencing Resolves Spatiotemporal Development of Pre-thymic Lymphoid Progenitors and Thymus Organogenesis in Human Embryos 4.98
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 4.95
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 4.95
Global transcriptome analysis of HAP1 cells 4.93
Short and Long RNA sequencing of human mature erythrocytes 4.92
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 4.92
The landscape of alternative splicing in aggressive prostate cancers 4.92
A role for ZNF598 in post-transcriptional gene regulation 4.89
List of TIAM1 differentially expressed genes in SW620 cells [RNA-seq] 4.89
The inhibitory effect of TIAM1 on TAZ transcriptional activity and TIAM1 differentially expressed genes 4.89
Transcriptome analysis of U87 cells upon LINC00152 knockdown 4.88
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 4.87
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 4.87
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 4.87
Transcriptome analysis of H9 hESC derived cerebral organoids 4.86
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 4.85
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 4.8
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 4.8
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 4.79
Global Mapping of Human RNA-RNA Interactions 4.78
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 4.77
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 4.75
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 4.75
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 4.72
Characterization of parental and rociletinib-resistant derived H1975 cell lines 4.7
Genetic and pharmacological restoration of TET2 function blocks stem cell self-renewal and progression of leukemia 4.7
RNA-sequencing of human leukemia cells and mouse hematopoietic progenitors 4.7
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 4.67
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 4.67
MYC interacts with the G9a histone methyltransferase to drive transcriptional repression and tumorigenesis 4.67
scRNASeq analysis of cycling cardiomyocytes 4.67
The Human Testis Cell Atlas via Single-cell RNA-seq 4.66
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 4.65
A549 cells and MSR-A549 cells 4.65
Total RNA was extracted from three samples of CD33 CAR or control T cells from three different donors 4.64
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation 4.63
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 4.62
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 4.62
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 4.6
Differentially expressed (DE) genes analysis in synovial fluid mesenchymal stem cells (SF-MSCs), SF-MSC derived iPSCs and iPSC derived MSCs (iPSC-MSCs) 4.57
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 4.57
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 4.56
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 4.56
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 4.56
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 4.56
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo 4.52
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo [RNA-seq] 4.52
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 4.52
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 4.52
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 4.5
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 4.48
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 4.48
Nucleoporin-mediated regulation of cell identity genes 4.46
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 4.44
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 4.44
RNA-seq of naive and primed ES cells (NHSM) 4.43
The Developmental Heterogeneity of Human Natural Killer Cells Defined by Single-cell Transcriptome 4.4
Global analysis of enhancer targets: Mosaic-seq 4.39
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 4.36
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 4.36
BRG1 governs Glucocorticoid Receptor interactions with chromatin and pioneer factors across the genome 4.36
Effect of selective glucocorticoid receptor modulation (SGRM) on gene expression in human prostate cancer cell lines 4.36
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 4.35
Effect of PDZ domain binding Kinase inhibition using TOPK-32 (called PBKi) on C4-2 cell transcriptome 4.34
FOXP3 protects conventional human T cells from premature restimulation-induced cell death 4.34
Examining serotonergic neuron differentiation from human iPSCs 4.32
Human embryonic stem cell, chimpanzee induced pluripotent stem cell, orangutan induced pluripotent stem cell, rhesus embryonic stem cell, and their derived cortical organoid RNA-seq 4.32
Transcriptome analysis of SKI knock-out in HL60 cells 4.31
Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1 4.31
Downregulation of DDX5/DDX17 and REST 4.3
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 4.28
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 4.27
RNA-Seq with and without RNase treatment in PCa cell lines 4.27
SREBP1 drives Keratin 80-dependent cytoskeletal changes and invasive behavior in endocrine resistant ERα breast cancer 4.26
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 4.2
Gene expression changes due to PARP knockdown in human cells 4.12
Transcriptional profile of human STAT1-/- fibroblasts expressing LY6E or empty control vector 4.12
Transcriptional Signatures of Hypoxic and Inflammatory Renal Epithelial Injury 4.09
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells 4.07
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 4.05
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 4.05
In vitro modeling of human germ cell development using pluripotent stem cells 4.02
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 4.0
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 3.99
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 3.99
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 3.95
Seletive inhibition of CDK9 in DLBCL cell lines 3.89
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 3.88
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 3.87
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 3.84
The cohesin release factor WAPL restricts chromatin loop extension. 3.82
The cohesin release factor WAPL restricts chromatin loop extension. [RNA-Seq] 3.82
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 3.81
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 3.8
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 3.8
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 3.79
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 3.78
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 3.78
Unique features and clinical importance of acute alloreactive immune responses 3.77
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 3.77
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 3.74
U2AF1 mutations alter splice site recognition in hematological malignancies 3.73
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 3.71
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 3.71
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 3.69
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 3.68
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 3.66
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 3.64
TGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity 3.63
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 3.63
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 3.63
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 3.6
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 3.59
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability 3.59
Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability [ RNA-seq] 3.59
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 3.58
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 3.58
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 3.57
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 3.57
Integrin signaling regulates YAP/TAZ to control skin homeostasis 3.55
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 3.52
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation 3.47
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 3.45
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 3.45
Transcriptome analysis of BAP1 knockout and restoration 3.45
Absence of NKG2D ligands defines human leukaemia stem cells and mediates their immune evasion 3.44
Generation of KRAS signatures using immortalized isogenic lung cells. 3.42
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 3.39
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 3.39
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 3.38
Gene expression profiles of primary human NK cells before and after expansion on CSTX002 feeder cells, with and without IL-21 stimulation 3.34
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 3.34
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 3.31
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 3.3
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 3.3
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 3.28
The cohesin complex prevents Myc-induced replication stress 3.28
An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis 3.22
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 3.21
RNA expression analysis of neuroblastoma cell lines treated with epigenetic drugs 3.2
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 3.19
KSDM1b Role in Ewing Sarcoma 3.17
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 3.16
NSD2 overexpression links drives clustered chromatin and transcriptional changes in a subset of insulated domains of insulated domains 3.15
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice 3.14
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice [RNA-seq] 3.14
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 3.11
FBXW7 modulates stress response by post-translational modification of HSF1 3.11
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 3.11
Identification of a core p53 transcriptional program with highly fractionated tumor suppressive activity 3.11
GRO-seq from HCT116, MCF7 and SJSA cell lines treated with DMSO and Nutlin 3.11
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery 3.1
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery (RNA-seq data set) 3.1
Single-cell transcriptome of human epithelial cells reveals novel insights into early innate immune responses to influenza virus and viral antagonism 3.04
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 3.04
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 3.02
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 3.01
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 2.98
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 2.98
Total RNA-seq in ALL-SIL upon TLX1 knockdown 2.92
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 2.86
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 2.86
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II] 2.84
Single-cell Transcriptomics reveals multi-step adaptations to endocrine therapy 2.83
LIN28A Over-expression RNAseq 2.83
Epigenetic reprogramming of melanoma cells by vitamin C treatment 2.81
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 2.81
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 2.81
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7 2.79
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 2.79
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures 2.78
Tumor- and cytokine-primed human natural killer cells exhibit distinct phenotypic and transcriptional signatures [RNA-seq] 2.78
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 2.76
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer 2.76
Transcriptome-wide identification of CELF2 functional targets in T cells 2.75
RNA-seq expression data from EB-HSPC after AM580 treatment compated to DMSO-trated and FL-HSPCs 2.65
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 2.61
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 2.59
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 2.56
Rnase L reprograms translation by widespread mRNA turnover escaped by antiviral mRNAs 2.55
Non-coding and coding transcriptional profiles are significantly altered in pediatric Retinoblastoma tumors 2.55
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 2.54
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer 2.49
Estrogen-independent molecular actions of mutant estrogen receptor alpha in endometrial cancer [RNA-seq] 2.49
O-glcnAc reprograms cellular energetics 2.48
eVIP2: Expression-based variant impact phenotyping to predict the function of gene variants 2.47
Global transcriptomic analyses of bronchial epithelial cells exposed to 5 ng/mL TGF-β1 and 10 nM Estrogen individually and in combination 2.47
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family 2.46
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family (RNA-seq) 2.46
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 2.45
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) 2.43
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 2.34
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 2.34
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 2.26
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 2.26
RNA-seq analysis of control and Myc-induced U2OS cells 2.24
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 2.22
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma 2.22
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma (RNA-Seq) 2.22
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 2.19
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal 2.19
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal [RNA-Seq] 2.19
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma [RNA-seq] 2.18
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma 2.18
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 2.18
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 2.13
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 2.13
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 2.06
Genome-wide discovery of human splicing branchpoints [RNAse] 2.06
ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex 2.04
Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome 2.04
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 2.04
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 1.98
CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair 1.91
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 1.91
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 1.83
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 1.77
Silencing p300 in MCF7 cells to study expression and alternative splicing 1.71
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 1.69
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 1.68
Osmostress induced changes of chromatin architecture and transcription in mammalian cells 1.65
Osmostress induced changes of chromatin architecture and transcription in mammalian cells [RNA-Seq, HiC] 1.65
K562 polyA RNA-Seq 1.64
single cell RNA-seq from GM12878 (ENCSR673UIY) 1.61
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma non-targeting shRNA negative control (SHC002V) with puromycin selection RNAseq 1.57
Sequencing of matched pair samples (diagnosis and relapse) in human B-cell acute lymphoblastic leukemia cells (ALL) 1.56
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 1.55
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 1.55
MCF-7 as a model for functional analysis of breast cancer risk variants 1.55
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ 10x genomics] 1.51
In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity 1.48
RNA-seq analysis of control and CDK12-depleted ovarian cancer cells 1.47
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 1.45
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 1.45
Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular 1.4
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 1.35
Ribosomal protein RPL26 is the principal target of UFMylation 1.34
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 1.29
SLIGRL-induced gene expression changes in NHEK cells 1.26
RNA-Seq of cKIT+ sorted cells from 53-137 day old fetal testes and ovaries and RNA-Seq of TRA-1-81+ H1 and UCLA1 hESCs. 1.26
cKIT+ sorted cells from 57-137 day old fetal testes and ovaries 1.26
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 1.26
Function and hormonal regulation of GATA3 in human first trimester placentation 1.25
Identification of long noncoding RNAs regulated by p53 1.14
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 1.09
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 1.09
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 1.09
RNA sequencing analysis of selumetinib-resistant CRC cells lines 1.09
Neurofibromin is an Estrogen Receptor alpha Transcriptional Co-repressor in Breast cancer 1.03
Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing 1.02
JAG1 Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium 1.02
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 0.92
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 0.92
Time series total RNA sequencing of a differentiation of human embryonic stem cells towards trophoblast lineage 0.89
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 0.89
6mer seed toxicity in tumour suppressive microRNAs 0.85
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 0.82
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 0.76
Transcriptome-wide analysis of the role of HTLV-1 Tax PBM in T-Cells from infected humanized-mice (hu-Mice) 0.74
Single-Cell reconstruction of differentiation trajectory reveals essential dynamics in human cardiac lineage commitment 0.73
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.69
Comparison of single-cell transcriptomics quality between unfixed cells and cells that were fixed and mock stained according to the RAID procedure 0.67
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 0.6
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 0.6
Club cells surviving influenza A virus infection induce temporary non-specific anti-viral immunity 0.58
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation (Ribo-seq, RNA-seq) 0.58
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 0.55
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 0.52
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [GSKJ4_RNA-seq] 0.49
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 0.45
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 0.45
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.45
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 0.43
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.4
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 0.39
RNA-seq of CD33 KO and control HSPCs 0.3
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 0.29
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer [RNA-seq] 0.27
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer 0.27
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 0.23
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 0.23
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 0.21
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 0.21
Impact on erythroid progenitor type on erythroid differntiation 0.19
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.12
Transcriptome profiling of A2M treated A549 Cell Line Samples 0.11
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 0.09
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 0.09
Transcriptome-wide modulation of splicing by the exon junction complex 0.09
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 0.06
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 0.05
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 0.03
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 0.03
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 0.03
SNHG5 siRNA knock down in HCT116 cells 0.01


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