Gene Query: PSRC1

Dataset Description Geneva Score
scRNASeq analysis of cycling cardiomyocytes 46.2
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 46.12
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 37.21
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 36.99
Single Cell Analysis Reveals Unexpected Transcriptional Heterogeneity of Neural Progenitors in the Developing Human Cortex 34.61
Gene expression changes after depletion of Cyclin F and atypical E2Fs in HeLa cells. 29.6
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 29.54
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 26.34
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 24.86
Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function 23.81
Comparing gene expression in iPSC derived RPE from control and AMD donors 23.27
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 22.98
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export II 20.77
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 19.37
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 19.35
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 19.09
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 19.09
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 18.21
Targeting JNK Pathway Expands Human Hematopoietic Stem Cells 18.12
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 18.07
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest 17.94
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 17.55
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 17.12
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 16.56
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 16.42
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 16.41
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts 15.64
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 15.56
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 15.04
Next Generation Sequencing Compares Effects of microRNA-9 perturbation in control and SZ hiPSC NPCs 14.63
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 13.83
Next Generation RNA Sequencing Analysis of AMPK Wild Type, AMPKα-KO and AMPKα1-2A U2OS cell Transcriptomes 13.76
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 13.66
A common cell state in Triple Negative Breast Cancers represents a druggable vulnerability 13.52
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 13.5
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 13.08
microRNA-seq and RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 12.99
RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 12.99
Regulation of protein translation during mitosis 12.94
Genome wide expression change in LCC2 and MCF-7 cells 12.89
Next generation sequencing of human hepatic stellate cell line, LX-2 treated with recombinant human TGF-β1, with DMSO or ML290 (5 µM) for 72h. 12.81
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 12.5
RNA-Seq profiling of day 7 and day 18 kidney organoids differentiated in two batches 12.4
Suppression of the FOXM1 transcriptional program via novel small molecule inhibition 12.11
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes 11.73
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes [RNA-Seq] 11.73
RNAseq analysis of ESRP regulated splicing events in prostate cancer 11.61
Effect of the knockdown of MLL1 and MLL2 on pediatric high grade glioma 11.53
Vitamin C dependent KDM6 demethylation specifies a functional chromatin state for endothelial-to-hematopoietic transition [RNA-Seq] 11.4
Vitamin C–dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition 11.4
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 11.33
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 11.16
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 10.97
Next Generation Sequencing of human SMA and healthy control Motor Neurons 10.96
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 10.95
Co-regulation of splicing by Rbfox1 and hnRNP M 10.9
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 10.9
Strand-specific Dual RNA-seq of Bronchial Epithelial cells Infected with Influenza A/H3N2 Viruses Reveals Splicing of Gene Segment 6 and Novel Host-Virus Interactions 10.87
Regionally distinct astrocyte interferon signaling promotes blood-brain barrier integrity and limits immunopathology during neurotropic viral infection 10.82
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 10.79
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 10.75
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 10.72
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 10.72
Global Transcriptional analysis of human spinal cord and neocortical neuroepithelial stem (NES) cells 10.63
Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D 10.51
The BCL6 RD2 domain governs commitment of activated B-cells to form germinal centers 10.45
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 10.37
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 10.33
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 10.19
Genome-wide transcriptional response to random aneuploidy in human cells 10.17
transcriptome studies of BRD4 inhibitor BDF-1253 on renal clear carcinoma 786-O cells 10.16
Differential gene expression analysis between proliferating and quiescent human dermal fibroblasts 9.95
Novel Targeting of Transcription and Metabolism in Glioblastoma 9.85
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 9.79
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 9.79
Total RNA sequencing of APC mutant and wt colonic organoids 9.67
p38 SAPK and SKIIP induced changes in alternative splicing patterns upon osmostress 9.64
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 9.63
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes 9.54
Pomalidomide inhibits PD-L1 induction to promote anti-tumor immunity 9.36
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion 9.3
SRSF2 mutations impair hematopoiesis and alter exon recognition 9.26
Survival of pancreatic cancer cells lacking KRAS function 9.22
Multiple sclerosis and EAE 9.19
Human optic chiasm from healthy controls and multiple sclerosis patients 9.19
MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma 9.12
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 8.94
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency [RNA-seq] 8.82
Low cytosolic folate cycling is a hallmark of U251 glioblastoma cells reprogramming towards pluripotency 8.82
PRDM1 inhibits proliferation of human colon cancer organoids 8.71
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 8.69
RNA-seq of shEZH2 cells 8.67
EWSR1 influences alternative splicing through direct and indirect mechanisms 8.63
FOXP1 orchestration of ASD-relevant signaling pathways. 8.36
DJ-1 is dispensable for human stem cell homeostasis 8.3
RNA-seq analysis to identify the genes regulated by p53-SET interplay 8.27
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 8.23
Transcriptional profiling of LS1034 cells treated with tepoxalin 8.2
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 8.19
Telomere-Dependent and Telomere-Independent Roles of RAP1 in Regulating Human Stem Cell Homeostasis 8.18
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 8.18
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 8.18
RNA-seq analysis of control and Myc-induced U2OS cells 8.17
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 8.09
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 8.06
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 8.05
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 8.04
The regulartory role of ZCCHC24 in splicing machinery 8.03
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 7.98
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 7.96
Sequencing of messenger RNAs with N6-methyladenosine modifications in acute myeloid leukemia (AML) with and without forced expression of FTO 7.91
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 7.84
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 7.83
Single-Cell Transcriptome Analysis of Lineage Diversity and Microenvironment in High-Grade Glioma 7.8
ChIP-seq and RNA-seq from human lymphoma cell lines 7.79
RNA-seq data from human lymphoma cell lines 7.79
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 7.75
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 7.62
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 7.53
RNAseq Study in CC-671 Treated Cal-51 Cells 7.42
UBC9 knockdown in bladder cancer T24 cell lines 7.3
RNA-sequencing experiment: Treatment of MCF-7 breast cancer cells with the novel small molecule ZNA 7.22
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 7.14
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 7.14
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 7.08
Transcriptional profiling of MCF7 cells treated with H3B05942, E2, or standard of care compounds 6.95
yylncT acts as a gatekeeper of the mesodermal transcriptional program by local modulation of DNMT3B [human_2] 6.94
Gene expression data from IMR90 control, IMR90 shRRM2 and shRRM2/shp16 6.93
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 6.92
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 6.92
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 6.92
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability [RNA-Seq] 6.9
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability 6.9
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 6.89
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 6.88
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 6.8
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 6.8
Gene expression in PANC1 cells treated with Rakicidin 6.72
RNA splicing alteration on glioblastoma and normal neural stem cells 6.67
Effect of disulfiram treatment on pediatric high grade glioma 6.66
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 6.63
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 6.63
Differential gene expression profiles in imatinib-resistant cell lines 6.6
Elucidating the microRNA-203 specific biological processes in glioblastoma cells from comprehensive high-throughput RNA-sequencing transcriptome profiling 6.59
RNA-seq in HT-29 colorectal cancer cells after F. nucleatum treatment 6.56
RNAseq to determine whether bidirectional transcription occurs over transposable elements following depletion of SETDB1 in THP-1 AML Cells 6.55
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 6.54
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling 6.49
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling (mRNA) 6.49
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 6.48
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 6.44
PNET animal model: new insights (II) 6.44
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  6.39
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 6.38
Epigenetic Lanscape and BRD4 Transcriptional Dependency of PAX3-FOXO1 Driven Rhabdomyosarcoma 6.37
PAX3-FOXO1 requires BRD4 to drive oncogene addiction in RMS cells [RNA-seq] 6.37
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 6.36
Activity-dependent transcriptional changes in human neurons 6.32
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 6.27
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 6.27
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 6.24
Nascent RNA Sequencing after NMYC activation in SH-EP MYCNER cells 6.23
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 6.14
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 6.13
Transcriptome analysis of Zika infected neural stem cells 6.11
Zika infected neural stem cells 6.11
Transcriptome analysis of U87 cells upon LINC00152 knockdown 6.11
A code of mono-phosphorylation modulates the function of RB. 6.07
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq] 6.06
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation 6.06
Therapeutic targeting of KDM1A/LSD1 in Ewing sarcoma engages the ER-stress response II 6.03
CASZ1 directly regulates expression of myogenic genes through regional epigenetic modifications to induce muscle and rhabdomyosarcoma cell differentiation 6.02
Functional astrocytes differentiated from hiPSCs 6.02
Epigenetic reprogramming at estrogen-receptor binding sites alters the 3D chromatin landscape in endocrine resistant breast cancer [RNA-seq] 5.97
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine resistant breast cancer 5.97
RNA sequencing reveals transcriptional changes after Hippo signaling activation in podocytes 5.96
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 5.95
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 5.91
Transcriptional study of ARN8 cells treated with novel DHODH inhibitors 5.9
RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 5.9
RNA-seq Profiles in RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 5.9
Disruption of GRIN2B impairs differentiation in human neurons 5.9
Total RNA-seq in ALL-SIL upon JQ1 inhibition 5.89
High-efficiency RNA-based reprogramming of human primary fibroblasts 5.81
The lung-enriched p53 mutants V157F and R158L/P regulate a novel transcriptome in lung cancer 5.8
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 5.71
Carcinoma-astrocyte gap junctions promote brain metastasis by cytosolic dsDNA response transfer 5.7
Differentially expressed vascular development genes for iPSC-ECs from CDI 5.68
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 5.68
Gene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4 5.67
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 5.66
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 5.65
STRIPAK directs PP2A activity to promote oncogenic transformation 5.64
Total RNA sequencing of WT intestinal orgaonids. 5.64
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 5.63
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 5.61
Gene Expression Profiling of WT and KDM3A Knocked out Cell 5.61
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 5.5
Effect of CHKA knockdown on C4-2 cell transcriptome 5.49
Combined use of astragalus polysaccharide and berberine attenuates insulin resistance in IR-HepG2 cells via regulation of the gluconeogenesis signaling pathway 5.48
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability [RNA-seq] 5.47
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability 5.47
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 5.45
Downregulation of DDX5/DDX17 and REST 5.42
The Promyelocytic Leukemia Zinc Finger Dependent Transcriptome during Human Endometrial Stromal Cell Decidualization 5.4
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 5.39
Gene Expression of Breast Cancer Cell Lines Across Biomaterial Platforms 5.39
Genes significantly down or Up-regulated upon RNF219 knockdown. [RNA-Seq] 5.35
Poly(ADP-ribosyl)ation dependent changes in CTCF-chromatin binding and gene expression in breast cells 5.34
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 5.33
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 5.33
Sequencing Universal Human Reference RNA by Smart-seq and early barcoding library preparation methods 5.32
KMT2C medaites the estrogen dependence of breast cancer through regulation of ERα enhancer function 5.31
MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway 5.31
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 5.28
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 5.28
Analyzing the interactions of mRNAs, miRNAs, lncRNAs and circRNAs to predict competing endogenous RNA networks in glioblastoma 5.27
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 5.26
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 5.24
Transcriptomics profiling of Alzheimer’s disease reveal novel molecular targets 5.22
Neurofibromin is an Estrogen Receptor alpha Transcriptional Co-repressor in Breast cancer 5.19
RNA-Seq of polysome profiling fractions and whole cell lysates of UVB-irradiated N-TERT keratinocytes 5.18
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 5.16
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 5.1
Downregulation of LATS kinases alters p53 to promote cell migration 5.09
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 5.08
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 5.08
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 5.08
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 5.06
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 5.03
WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription 5.02
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex 5.01
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 5.01
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 5.0
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells 4.95
Effect of drugs on transcriptomic profiles 4.89
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-seq of KLF6 KO) 4.84
RNA-sequencing analysis of glucose and acetate regulated transcripts in glioblastoma cells 4.84
Reduced CYFIP1 in human neural progenitors as 15q11.2 deletion model: donor specific dysregulation of schizophrenia/epilepsy genes 4.83
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 4.83
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 4.81
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 4.78
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 4.77
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 4.77
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 4.75
Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors 4.75
Human Adipocytes Regulate Gene Expression in Triple-negative Breast Cancer Assessed by NGS Sequencing 4.74
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 4.74
Antiviral innate immunity of hepatitis C virus-infected stem cell-derived hepatocytes 4.73
Differentially expressed (DE) genes analysis in synovial fluid mesenchymal stem cells (SF-MSCs), SF-MSC derived iPSCs and iPSC derived MSCs (iPSC-MSCs) 4.71
U2AF1 mutations alter splice site recognition in hematological malignancies 4.66
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 4.66
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors [RNA-seq] 4.65
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors 4.65
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 4.65
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 4.63
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq Human] 4.59
Steroid Receptor Coactivator-2 Regulated Transcriptome in Human Endometrial Stromal Cells 4.58
Cajal bodies are linked to genome conformation 4.58
Cajal bodies are linked to genome conformation [RNA-Seq] 4.58
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 4.57
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not 4.57
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells 4.57
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [ChIP-Seq & RNA-Seq] 4.57
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 4.54
RNA-seq transcriptonal profiling in human K562 cells with or without dCas9 and sgRNAs 4.52
In situ CAPTURE of chromatin interactions by biotinylated dCas9 4.52
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [RNA-seq] 4.5
Rescue of Fragile X syndrome by DNA methylation editing of the FMR1 4.5
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 4.46
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 4.45
ENCODE Cold Spring Harbor Labs Long RNA-seq 4.44
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 4.43
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 4.43
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 4.39
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 4.36
m6A level and isoform characterization sequencing (m6A-LAIC-seq) reveal the census and complexity of the m6A epitranscriptome 4.33
Gene expression in GBM with Cav3.2 inhibition 4.31
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 4.31
Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes 4.31
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells [RNA-seq] 4.3
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells 4.3
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 4.28
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 4.27
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 4.24
TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma 4.19
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation [RNA-seq] 4.17
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation 4.17
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 4.16
DAOY-NERT2 Notch/Hypoxia Transcriptome Analysis 4.1
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 4.08
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 4.07
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 4.07
Chronophin regulates metabolic and transcriptomic features of glioblastoma stem-like cells 4.07
RNA-seq of Human neck of femur (NOF) fracture hip and osteoarthritic (OA) cartilage 4.06
Long noncoding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells 4.06
snRNAs as regulators of alternative splicing 4.06
Generating Patterned Kidney Organoids for Studying Development and Diseases 4.05
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 4.05
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 4.03
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 4.03
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 4.01
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 4.01
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 4.01
mRNA sequencing of clinical-grade neural stem cells derived from human ES cells 4.0
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 3.99
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 3.99
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 3.95
The chromatin modifier CHD8 targets autism risk genes during human neurodevelopment  3.93
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes. 3.92
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq] 3.92
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 3.89
EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling 3.87
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 3.87
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 3.84
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 3.83
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 3.81
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 3.8
Transcriptional profiling of microglia; current state of the art and future perspectives 3.79
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 3.79
Human embryonic stem cell, chimpanzee induced pluripotent stem cell, orangutan induced pluripotent stem cell, rhesus embryonic stem cell, and their derived cortical organoid RNA-seq 3.77
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 3.76
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 3.75
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 3.74
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 3.74
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability] 3.74
RNASeq of mouse, human, and non-human primate primary dermal fibroblasts to poly(I:C) transfection 3.71
Bone marrow derived human B cells [normal proB] 3.7
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 3.65
Gene expression changes due to PARP knockdown in human cells 3.59
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 3.54
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 3.53
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 3.48
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 3.48
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 3.47
Hyper-activation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2 3.45
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 3.43
The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner 3.37
Kidney organoid reproducibility across multiple human iPSC lines and diminished off target cells after transplantation revealed by single cell transcriptomics 3.34
High-throughput sequencing of pluripotent cells 3.25
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 3.22
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery 3.21
Arginine methylation controls cell proliferation by integrating E2F activity with the splicing machinery (RNA-seq data set) 3.21
Illumina Total RNA-seq in HeLa 3.06
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 3.06
Dynamic reorganization of nuclear architecture during human cardiogenesis [RNA-seq] 3.0
Dynamic reorganization of nuclear architecture during human cardiogenesis 3.0
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 2.97
Estrogen response in breast cancer cell line MCF-7 is dependent on NR2F2 [RNA-seq] 2.95
NR2F2 study 2.95
RNA-seq of hiPSCs-derived NPCs from 3 pairs of dizygotic discordant twins for Congenital Zika syndrome 2.93
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 2.92
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 2.92
Single-Cell reconstruction of differentiation trajectory reveals essential dynamics in human cardiac lineage commitment 2.85
Differential responses of human fetal brain neural stem cells to Zika virus infection 2.78
Non-transmissible measles virus vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells 2.7
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration [Microfluidics] 2.7
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 2.68
SILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors 2.65
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 2.64
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes 2.57
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 2.57
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation 2.52
Dissecting neural differentiation regulatory networks through epigenetic footprinting 2.52
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 2.51
Multiple roles for Grainyheadlike transcription factors in the establishment and maintenance of human mucociliary airway epithelium 2.46
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 2.42
Long Non-coding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity 2.4
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 2.4
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 2.4
The bromodomain protein BRD4 regulates splicing during heat shock 2.39
The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis 2.36
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 2.35
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 2.31
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 2.31
Analysis of gene expression in SKOV3 ovarian cancer cells after knockdown of the long non-coding RNA DNM3OS 2.25
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 2.21
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 2.19
Next-generation RNA sequencing to determine changes in gene expression during breast cancer progression 2.12
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 2.11
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 2.11
FGF2 regulation of gene expression in stable inducible Neurons 2.1
X-Ray induced DNA-Hydroxymethylation changes 2.08
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 2.07
Enriched retinal ganglion cells derived from human embryonic stem cells (RNA-seq) 2.03
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 2.03
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 1.94
RNA-seq analysis upon ARID1B overexpression 1.93
A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism 1.93
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff 1.9
Gene expression profile in breast cancer cells 1.88
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 1.88
Inhibition of H3K4 demethylation induces autophagy in cancer cell lines 1.84
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 1.83
Profiling gene expression changes in ovarian cancer cells seeded on 3D organotypic culture of omentum 1.76
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 1.72
Tracking transcriptional changes in a species-specific manner during experimental hepatoblastoma progression in vivo 1.69
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 1.67
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 1.65
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 1.65
The Glioma-Infiltrating T Cell Receptor Repertoire 1.65
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 1.64
Knockout of miR-221 and miR-222 reveals overlapping and specific function between paralogous miRNAs 1.62
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 1.61
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 1.61
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 1.57
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 1.57
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 1.56
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 1.56
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 1.55
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 1.52
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 1.5
KSDM1b Role in Ewing Sarcoma 1.47
CD133hi, Notchhi, DP (double positive) and DN (double negative) in GBML8 and GBML20, both patient-derived glioblastoma tumorsphere cultures 1.46
The cohesin complex prevents Myc-induced replication stress 1.45
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 1.37
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 1.31
The effect of PPARG inhibition on human angiomyolipoma cells 1.31
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 1.3
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 1.3
iPSC derived motor neuron cultures from C9ORF72 carriers 1.3
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 1.29
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 1.25
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 1.25
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 1.24
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 1.24
Interaction between mitoNEET and NAF-1 in cancer cells 1.22
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 1.18
Non-coding and coding transcriptional profiles are significantly altered in pediatric Retinoblastoma tumors 1.18
Transcriptome sequencing of K-562 cells 1.18
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 1.16
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 1.16
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies 1.15
DRB/GRO-Seq -/+ UV 1.12
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 1.1
Transcriptome profiling of 5 human adenocarcinoma cell lines 1.06
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 1.06
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 1.04
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 0.98
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 0.96
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 0.96
Non-synchronized cell cycle transcriptomics in U2OS and HeLa cancer cells 0.92
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 0.87
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells 0.86
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations 0.85
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq] 0.85
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 0.82
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 0.82
Efficient derivation of microglia-like cells from human pluripotent stem cells 0.82
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration 0.8
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 [RNA-seq] 0.79
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 0.79
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 0.76
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 0.73
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons 0.72
hNSCs siRNA NOVA2 0.69
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.67
RNA-seq of naive and primed ES cells 0.67
Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer 0.66
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 0.66
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 0.63
DAOY-Notch1/Notch2 knockout: transcriptome comparison 0.62
CDK12 mediated transcriptional regulation in U2OS cells 0.61
N6-methyladenine DNA Modification in Glioblastoma 0.59
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 0.59
The role of the Calcium-Sensing receptor in colorectal cancer 0.58
Genome-wide analysis of the Integrator complex 0.57
Genome-wide analysis of the Integrator complex (HTS) 0.57
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 0.55
Hyper-excitability of Neurons generated from Patients with Bipolar Disorder 0.54
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 0.51
Drug combination of 17-AAG and Belinostat on MDA-MB-231 breast cancer cells 0.47
MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block 0.46
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition 0.46
Increased Neanderthal ancestry in genomic regions associated with lipid catabolism in contemporary Europeans 0.45
Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells 0.41
Role of FGFR1 in neuronal devlopment 0.4
H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 0.4
RNA-seq of H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 0.4
The circadian transcriptional landscape in primary human mammary epithelial cells 0.33
A bioinformatics approach reveals novel mechanisms of the OVOL transcription factors in the regulation of epithelial-mesenchymal cell programming and cancer progression. 0.32
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 0.31
The global transcriptome analysis in the time course of hESC-derived cardiac differentiation 0.3
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 0.29
Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease 0.27
Transcriptome analysis of human embryonic stem cells (hESCs) upon siRNA-mediated knockdown of hESC-essential genes 0.26
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 0.25
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.25
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.25
High-resolution comparative analysis of great ape genomes 0.2
Function and hormonal regulation of GATA3 in human first trimester placentation 0.17
A histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing 0.17
RNA-Seq characterization of human H1-derived NPC differentiation timecourse 0.17
The transition from proliferation to quiescence in glioblastoma stem-like cells requires Ca2+ signaling and mitochondria remodeling 0.15
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 0.11
RNA editing in nascent RNA affects pre-mRNA splicing 0.07
Gene expression from AsPC-1 cells treated with PTC596 and DMSO 0.07
Regulation of poly(A) tail and translation during the somatic cell cycle 0.07
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 0.05
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 0.03


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