Gene Query: QDPR

Dataset Description Geneva Score
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 48.05
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 46.5
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 31.11
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 28.83
Effect of TUNAR silencing and GSK3 inhibition on human b-cell transcriptome 26.22
The X-linked DDX3X RNA helicase dictates translation re-programming and metastasis in melanoma 24.7
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain [RNA-Seq] 24.54
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain 24.54
Loss of the Chr16p11.2 candidate gene QPRT leads to aberrant neuronal differentiation 21.71
RNA-seq analysis of BAP1-depleted uveal melanoma cells 19.56
Gene-Centric Functional Dissection of Human Genetic Variation Uncovers Regulators of Hematopoiesis 18.66
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 18.05
Gene expression in mature and immature human ES-derived beta cells, and sorted beta-cells from adult islets 17.64
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [d7+d14] 16.87
Analyzing the interactions of mRNAs, miRNAs, lncRNAs and circRNAs to predict competing endogenous RNA networks in glioblastoma 16.45
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 16.07
Impact of dieldrin on transcription in Jurkat T cells 16.0
Global expression profiles in cardiac progenitor cells generated by ISX-9 15.72
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 15.72
RNA-seq profile of expanded human ST2-transduced Tregs cultured with IL-2 and TCR in the presence or absence of IL-33 15.63
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 14.9
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 14.41
High-throughput sequencing of the human hepatic progenitor cell niche in PSC and HCV. 14.17
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 14.08
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 14.08
Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma 13.91
Comparison of single-cell transcriptomics quality between unfixed cells and cells that were fixed and mock stained according to the RAID procedure 12.91
RNA sequencing of matched nephrectomy samples [RNA-seq] 12.78
Genome-wide maps of H3K36me3 in ccRCC and RNA-seq of matched nephrectomy samples 12.78
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 12.76
Functional interactions between Mi-2β and AP1 complexes control response and recovery from barrier disruption 12.71
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 12.27
RNA-Sequencing of human dermal lymphatic endothelial cells (HDLEC) treated with siRNA targeting YAP/TAZ and YAP5SA 12.2
Identification of transcription start sites for human A549 cell line using ReCappable-seq 12.15
The age and genomic integrity of neurons after cortical stroke in humans 11.63
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 11.59
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer [RNA-Seq] 11.24
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer 11.24
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 11.08
RNA-seq analysis of uveal melanoma cells treated with FR900359 10.92
Transcriptome analysis of human reninomas as an approach to understanding juxtaglomerular cell biology 10.68
Effect of circPTPRM on the biological behaviors of hepatocellular carcinoma cells in vitro and its clinical significance. 10.62
IGF2BP3 controls cancer cell invasiveness by modulation RISC function 10.47
The regulartory role of ZCCHC24 in splicing machinery 10.46
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 10.13
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing 10.11
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 10.11
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 9.94
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 9.94
Global Transcriptional analysis of human spinal cord and neocortical neuroepithelial stem (NES) cells 9.93
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 9.75
Human Long Intergenic Noncoding RNA Linc-ADAL Knockdown in Mature Adipocytes using Lentiviral ShRNA 9.51
ZNF131 suppresses centrosome fragmentation in Glioblastoma stem-like cells through regulation of HAUS5 9.5
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration 9.47
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+ T regulatory cells activation 9.43
Generation, transcriptome profiling, and functional validation of cone-enriched human retinal organoids 9.33
circRNA-sequencing 9.2
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 9.09
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response 9.05
Transcriptional responses of melanoma cells to BRAF inhibition 9.02
Human embryonic stem cell, chimpanzee induced pluripotent stem cell, orangutan induced pluripotent stem cell, rhesus embryonic stem cell, and their derived cortical organoid RNA-seq 8.95
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 8.93
RNA-seq data from human SGBS adipocytes differentiated with marine oxohexadecenoic acids 8.91
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration [Microfluidics] 8.86
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data 8.81
The Human Testis Cell Atlas via Single-cell RNA-seq (Healthy men scRNA-seq data set) 8.78
Transcriptome profiling of omental adipose tissues in human obesity by RNA-Seq 8.78
Genome wide mapping of polyadenylation sites in proliferating and contact-inhibited cells and cells with knockdown of cleavage and polyadenylation factors 8.7
scRNASeq analysis of cycling cardiomyocytes 8.69
Sequencing Universal Human Reference RNA by Smart-seq and early barcoding library preparation methods 8.63
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes 8.14
Characterization of Type I Interferon pathway during Hepatic Differentiation of Human Pluripotent Stem Cells and hepatitis C virus infection 8.12
Comprehensive comparative analysis of 5’ end RNA sequencing methods 8.12
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 8.02
Cell responses to dysregulated VZV-induced cell-cell fusion 8.0
Simultaneous quantification of antibody-RNA conjugates and the transcriptome from fixed cells by RAID 7.98
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 7.95
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 7.95
Seletive inhibition of CDK9 in DLBCL cell lines 7.86
The Glioma-Infiltrating T Cell Receptor Repertoire 7.82
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression 7.82
Mastermind-like 3 controls proliferation and differentiation in neuroblastoma (RNA-seq) 7.81
Mastermind-like 3 controls proliferation and differentiation in neuroblastoma 7.81
Comparative gene expression profiling of human primary endotheliocytes cultivated on polyurethane-based electrospun 3D matrices and natural decellularized vein 7.8
MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma 7.61
RNA seq data of Hep3B-control, Hep3B-sertraline, Hep3B-XL413, Hep3B-XL413-sertraline, Huh7-control, Huh7-sertraline, Huh7-XL413, Huh7-XL413-sertraline cells 7.61
3’READS+, a sensitive and accurate method for 3’ end sequencing of polyadenylated RNA 7.44
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 7.42
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation 7.42
RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms, and GTPase binding in bipolar disorder 7.4
The role of FAM46C in myeloma cells [sequencing] 7.36
The role of FAM46C in myeloma cells 7.36
Gene expression analysis of dengue-infected cells 7.31
Differential gene expression of human melanoma cells [RNA-seq] 7.31
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 7.31
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 7.29
Gene expression profile using RNA-seq in WC00060 or SR-0788 cells transfected with siRNA for KPC1 or control 7.28
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 7.15
Induction of human hemogenesis in adult fibroblasts by defined factors and hematopoietic co-culture 7.12
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 7.1
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 7.1
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 7.01
Transcriptomics profiles of patient-matched normal kidney and ccRCC pairs 7.01
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 6.99
Evaluating pre-clinical models for studying NASH driven HCC. 6.97
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 6.96
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 6.84
Maturation of human iNSCs 6.75
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 6.7
Cell-to-cell variation in defective virus expression and effect on host response during influenza virus infection 6.66
RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas 6.61
Transcriptome-wide analysis to determine miR-200a targets in melanoma cell lines 6.52
Divergent expression and metabolic functions of human glucuronosyltransferases through alternative splicing 6.36
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 6.35
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells 6.2
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells [RNA-seq] 6.2
Next Generation Sequencing of control (Untreated), PAN injured and Adriamycin injured human podocytes 6.14
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 6.1
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 6.08
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 6.08
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 6.02
A peninsular structure coordinates asynchronous differentiation with morphogenesis to generate pancreatic islets [bulk vs buds] 5.98
Quantitative profiling of the UGT transcriptome in human drug metabolizing tissues [Total RNA] 5.93
Global gene expression profiles of cardiomyocytes differentiated from human pluripotent stem cells (hiPSC-CMs) in 3D culture exposed to ethanol 5.93
Gene expression changes in human melanoma cell lines compared to primary melanocytes 5.88
Gene expression profile difference among renal location in a stone former 5.85
Polarized B -cell functions 5.8
Chromatin landscape of human visceral and subcutaneous adipocytes 5.72
mRNA and miRNA expression in primary human muscle cells treated with 1,25(OH)2D3 or vehicle 5.67
RNA expression in primary huamn muscle cells treated with 1,25(OH)2D3 or vehicle 5.67
Cooperative and Antagonistic Transcriptional Regulation by BRG/BRM [RNA-seq] 5.64
Co-regulation of transcription by BRG1 and Brm, two mutually exclusive SWI/SNF ATPase subunits 5.64
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 5.63
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 5.63
Transcriptional profile of CAOV2 ovarian cancer cells with TAZ silencing 5.61
Transcriptome analyses of human pancreatic islets and pseudoislets 5.61
Single-cell analysis of adult human ovary using 10X genomics 5.58
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 5.56
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation [RNA-Seq] 5.52
Dynamic and stable enhancer-promoter contacts regulate terminal differentiation 5.52
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes [RNA-Seq] 5.51
Genome wide transcriptome analysis of palbociclib or GSK3326595 treated A375 cells [Palbociclib_GSK_RNASeq] 5.51
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells 5.48
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 5.45
Gene Expression Analysis of Melanoma Cells Treated with 6-Thio-dG In Vitro 5.28
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 5.28
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 5.15
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 5.15
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 5.14
SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF 5.04
Genome-wide maps of transcriptomic and epigenomic state in melanoma cell lines 5.03
Trans-chromosomal regulation by a novel lincRNA required for adipogenesis that escapes X-chromosome inactivation 4.98
Human gut derived-organoids as model to study gluten response and effects of microbiota bioproducts in celiac disease 4.97
Tracking transcriptional changes in a species-specific manner during experimental hepatoblastoma progression in vivo 4.96
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 4.95
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 4.95
Gene expression analysis of human liver progenitor-like cells in culture 4.94
Gene expression signatures of innate lymphoid cells from human blood 4.92
Response of HEK293 Freestyle cells to 36 h of culture in Zn(II)-depleted Freestyle medium 4.86
RNA sequencing based comparative analysis of human hepatic progenitor cells and their niche from alcoholic steatohepatitis livers 4.84
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 4.8
Alternative splicing of differentiated myeloid cell transcripts after infection by Anaplasma phagocytophilum impacts a selective group of cellular programs 4.78
Global epigenomic reconfiguration during mammalian brain development 4.77
Whole genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver 4.77
Whole genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver [RNA-Seq] 4.77
Molecular Biomarkers Screened by Next-generation RNA Sequencing for non-sentinel lymph node status predicting in breast cancer patients with metastatic sentinel lymph node 4.75
Effect of disulfiram treatment on pediatric high grade glioma 4.75
Whole transcriptome RNA sequencing of human cells after HCV infection (ML-1 thyroid cell line, primary thyrocytes and Huh7.5 hepatocyte cell line) 4.68
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 4.67
Peptidomimetic blockade of MYB in acute myeloid leukemia 4.65
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 4.65
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 4.64
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 4.62
Pseudotime Ordering of Single Human Beta-Cells Reveals States of Insulin Production and Unfolded Protein Response 4.59
Expansion, in vivo-ex vivo cycling and genetic manipulation of primary human hepatocytes 4.55
Single-cell transcription profiling in KS1 patient iPSCs and NPCs 4.52
nELAVL HITS-CLIP in Alzheimer's Disease patients 4.51
Generating Patterned Kidney Organoids for Studying Development and Diseases 4.5
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 4.49
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 4.48
Transcriptomic and gene ontology profiling of the human corneal cell types 4.48
Transcriptome sequencing of K-562 cells 4.46
LncRNA DEANR1 facilitates human endoderm differentiation by activating FOXA2 expression 4.43
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 4.41
Hyper-excitability of Neurons generated from Patients with Bipolar Disorder 4.4
Cleavage Factor Im as a key regulator of 3’ UTR length 4.38
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability [RNA-Seq] 4.37
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability 4.37
POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells 4.36
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [RNA-Seq III] 4.29
Transcriptomic analysis of human tonsillar TFH subsets 4.28
Patient Derived Xenograft for Delivery of Precision Medicine in Castrate Resistant Prostate Cancer 4.26
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 4.25
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 4.24
Human iPSC-based Modeling of Late-Onset Disease using Progerin-induced Aging 4.21
RNA helicase A is necessary for KIF1Bβ tumor suppression in neuroblastoma 4.19
RNA-seq analysis of HT-29, MCF10A, and MDA-MB-436 cells 4.16
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 4.14
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 4.1
RNA-seq analysis of SKMEL28 melanoma cells following DIRC3 and IGFBP5 ASO knockdown 4.1
Mutation independent activation of the Notch pathway is associated with Lapatinib resistance in Her2+ breast cancer cell lines 4.07
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia 4.05
Lysine benzoylation is a novel histone mark [RNA-seq] 4.04
Lysine benzoylation is a novel histone mark 4.04
A20 regulates canonical wnt-signaling through an interaction with RIPK4 4.04
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 4.04
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 4.04
RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues 4.01
Next generation sequencing analysis of transcriptomes at different timepoints after chlorprothixene treatment in NB4 and Kasumi-1 cells 4.01
Repurposing of promoters and enhancers during mammalian evolution 3.97
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 3.95
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 3.94
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 3.94
Human Pancreatic Islets Expressing HNF1A Variant Have Defective β cell Transcriptional Regulatory Networks 3.92
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 3.91
mRNA Profiling of miR-17 family inhibition using TuD lentiviral vector in HepG2 and SK-Hep1 hepatocellular carcinoma cell lines [RNA-Seq] 3.9
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth 3.9
Transcriptome data from human endocrine cells recovered from mouse grafts with pre-engraftment controls 3.9
SNHG5 siRNA knock down in HCT116 cells 3.85
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma 3.74
CROP-Seq in Primary Human T Cells 3.72
Exercise-induced transcriptome changes in skeletal muscle adapted to aerobic training 3.68
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 3.65
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 3.62
Neuronal Development And The Onset Of Electrical Activity In The Human Enteric Nervous System 3.61
Regionally distinct astrocyte interferon signaling promotes blood-brain barrier integrity and limits immunopathology during neurotropic viral infection 3.6
Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas 3.55
RNA sequencing of BT142 and TS603 cell lines 3.55
Single-cell analysis of human kidney organoids 3.55
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 3.53
RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 3.53
microRNA-seq and RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 3.53
Multiple sclerosis and EAE 3.52
Human optic chiasm from healthy controls and multiple sclerosis patients 3.52
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor [human RNA-seq] 3.51
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor. 3.51
transcriptome studies of BRD4 inhibitor BDF-1253 on renal clear carcinoma 786-O cells 3.44
Identification of differential expressed genes of JQ1 or JQ1+Bortezomib in colorectal cancer cells 3.33
Gene expression changes caused by KRAS in MCF-10A 3.31
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 3.29
N6-methyladenine DNA Modification in Glioblastoma 3.29
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 3.29
A sister of NANOG regulates genes expressed in pre-implantation human development 3.28
RNA-sequencing with micro-dissected boundary organoid into anterior, posterior, and boundary regions 3.27
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 3.26
Iron response of HepG2 cells 3.21
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 3.19
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 3.19
Human Induced Pluripotent Stem Cells Recapitulate Breast Cancer Patients’ Predilection to Doxorubicin-Induced Cardiotoxicity 3.18
Transcriptional study of ARN8 cells treated with novel DHODH inhibitors 3.18
Global analysis of enhancer targets: Mosaic-seq 3.17
RNA splicing alteration on glioblastoma and normal neural stem cells 3.16
Integrating the Epigenome to Identify Novel Drivers of Hepatocellular Carcinoma 3.14
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 3.13
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 3.13
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 3.12
Similarity of therapeutic networks induced by a multi-component herbal remedy in neurovascular unit cells 3.11
Microvesicle-mediated delivery of miR-1343: impact on markers of fibrosis 3.06
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug [human] 3.04
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug 3.04
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 3.02
Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays 3.01
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 2.99
Carcinoma-astrocyte gap junctions promote brain metastasis by cytosolic dsDNA response transfer 2.98
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 2.9
Gene expression profile in breast cancer cell lines using RNA sequencing 2.9
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 2.89
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 2.88
The Cushing's disease adipose gene expression profile reveals effects of long term glucocorticoids on adipose tissue lipid, protein and glucose metabolism 2.87
Effects of Polybrominated Diphenyl Ether (PBDE) Mixture on estrogen receptor positive (ER+) patient-derived tumor xenograft (PDX) model 2.84
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 2.82
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 2.82
Non-coding regions are the main source of tumor-specific antigens [human] 2.82
Non-coding regions are the main source of tumor-specific antigens 2.82
Activity-dependent transcriptional changes in human neurons 2.82
Analyses of a panel of transcripts and construction of RNA networks in hepatocellular carcinoma 2.8
FOXP1 orchestration of ASD-relevant signaling pathways. 2.78
single cell RNA-seq from Purkinje cell (ENCSR888LYA) 2.78
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5’ and 3’ Ends of Genes 2.78
Identification of a LIF-responsive replication-competent human β cell 2.77
PRDM1 inhibits proliferation of human colon cancer organoids 2.76
RNA-Seq identifies condition-specific biological signatures of ischemia-reperfusion injury in the human kidney 2.74
Altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency 2.72
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 2.7
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 2.7
Patient-derived organoids (PDOs) model treatment response of metastatic gastrointestinal cancers. 2.69
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 2.68
Patient-derived xenograft platform for metastatic melanoma 2.67
RNA editing in nascent RNA affects pre-mRNA splicing 2.66
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 2.64
RNA-sequencing analysis of human fibrolamellar hepatocellular carcinoma and 4 maturational stages of the human hepatobiliary system 2.64
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 2.63
Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant 2.6
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 2.59
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 2.57
Analysis of human, chimpanzee, macaque and mouse tissue transcriptomes using Next Generation Sequencing 2.56
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma 2.53
Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability? 2.49
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells 2.49
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 2.46
RNA-seq, ChIP-seq and single cell RNA-seq of human skin Langerhans cells 2.44
RNA-seq of IL-4 stimulated human keratinocytes 2.42
Sequencing of ponatinib-resistant LC-2/ad derivatives (PR1 and PR2) and parental LC-2/ad cells 2.4
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [mutant MEF2C] 2.39
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes 2.39
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes 2.39
Measure transcript integrity using RNA-seq data 2.38
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 2.36
SLIGRL-induced gene expression changes in NHEK cells 2.36
CDK12 regulates alternative last exon mRNA splicing and promotes invasion of a breast cancer cell line 2.33
Generation and persistence of human tissue-resident memory T cells in lung transplantation 2.31
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 2.3
The Polycomb protein BMI1 induces an invasive gene expression signature in melanoma that promotes metastasis and chemoresistance. 2.29
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 2.29
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 2.28
The DNA methylation landscape of human melanoma [RNA-Seq] 2.27
The DNA methylation landscape of human melanoma 2.27
CHCHD2 gene KO effect in iPSC drived motor neurons 2.25
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 2.25
Dissecting the single-cell transcriptome network underlying gastric premalignant lesions and early gastric cancer [10x genomics] 2.25
Transcriptome analysis of immature and matured human oocytes from patients of young and advanced maternal age 2.24
Sex differences in transcriptomic profiles in aged kidney cells of renin lineage 2.23
The expression of genes encoding palmitoylated proteins in axonal and synaptic compartments is affected in CLN1/PPT1 transfected neuronal cells 2.22
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 2.19
A bioinformatics approach reveals novel mechanisms of the OVOL transcription factors in the regulation of epithelial-mesenchymal cell programming and cancer progression. 2.19
RNA-sequencing of pediatric idiopathic dilated cardiomyopathy patients and healthy controls 2.17
Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming 2.17
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 2.16
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 2.16
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 2.15
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 2.15
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development 2.14
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 2.14
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 2.1
To identify transcripts that are differentially expressed in the MYCN amplified vs MYCN non-amplified cell lines using Next Generation Sequencing 2.1
Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization  2.1
CUREfast: Accelerating research with families 2.08
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC [Total RNA-Seq] 2.08
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC 2.08
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 2.06
BioProject PRJNA381064: Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage (Gene expression profiling in several tetrapod species, bulk tissue RNA-seq) 2.06
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 2.05
Hepatitis C virus functionally sequesters miR-122 2.05
Gene expression in control and DOCK8 CRISPR KHYG1 NK cells 2.03
Single-cell RNA-Seq Investigation of Foveal and Peripheral Expression in the Human Retina 2.01
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 1.99
PSEN1ΔE9, APPswe and APOE4 confer disparate phenotypes in human iPSC-derived microglia 1.98
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 1.98
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 1.98
List of TIAM1 differentially expressed genes in SW620 cells [RNA-seq] 1.94
The inhibitory effect of TIAM1 on TAZ transcriptional activity and TIAM1 differentially expressed genes 1.94
RNAseq of Extracellular vesicle RNAs and cellular RNAs from HPASMCs with or without TGF-b1 or BMP4 treatment 1.84
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence 1.84
Transcriptome sequencing identify a recurrent CRYL1-IFT88 chimeric transcript in hepatocellular carcinoma 1.83
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 1.82
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 1.82
Short-term effect of Boost versus Radical doses of Intraoperative electron Radiotherapy in breast cancer tumor bed using high-throughput approaches 1.82
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 1.73
CXCR4 is a host factor that regulates Plasmodium development in hepatocytes 1.73
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 [3mRNA-seq] 1.69
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 1.69
Absence of NKG2D ligands defines human leukaemia stem cells and mediates their immune evasion 1.67
RNA Seq data: A375, A375R, A375DR vorinostat treated, and biopy samples from patients pre- and post- treated with Vorinostat 1.63
An acquired vulnerability of drug resistant melanoma with therapeutic potential 1.63
mRNA-sequencing of breast cancer subtypes and normal tissue 1.63
Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s 1.57
To investigate the decay constants (half-lives) of transcript isoforms generated by alternative polyadenylation in proliferating and quiescent cells 1.54
RNA-SEQ assay for wild type and CRISPR induced endoglin knockout human pulmonary artery smooth muscle cells (PASMC) 1.53
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer [RNA-Seq] 1.52
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer 1.52
Expression changes in melanoma cell lines pre MAPKi treatment vs. post-MAPKi resistance (RNA-seq_CellLine.batch2) 1.52
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 1.5
A genomic study of the contribution of DNA methylation to regulatory evolution in primates 1.5
RNAseq in Alzheimer's Disease patients 1.46
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 1.45
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 1.45
Molecular analysis of renal cell carcinoma with unclassfied histology [gene expression] 1.44
Molecular analysis of renal cell carcinoma with unclassfied histology 1.44
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 1.43
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 1.43
Human Treg NaCl stimulation 1.42
Single-cell transcriptomics of human oocytes: environment-driven metabolic competition and compensatory mechanisms during oocyte maturation 1.4
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 1.4
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription.[RNA-seq and ChIP-seq] 1.39
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription 1.39
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 1.38
Critical role for Lymphocytes in Producing FLT3LG in Tumors and Driving Checkpoint Therapy-Receptive Immune Microenvironments 1.37
Genome-wide maps of chromatin state and mRNA expression patterns in leukemic cell lines 1.35
Total RNAseq of human putamen and caudate nucleus tissues in healthy control and Bipolar Disorder individuals 1.34
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 1.34
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.34
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 1.33
SF3B1 Degron knockdown RNA-seq 1.32
Folate modulation induces chromosomal instability and higher proliferation of immortalized human keratinocytes 1.31
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 1.27
The effect of insulin on mRNA transcription of human pluripotent stem cells 1.24
Transcriptional effect of ETV1 knockdown in melanoma cells 1.23
eRNA: A graphic user interface-based tool for RNA sequencing data analysis 1.2
eRNA: A graphic user interface-based tool for RNA sequencing data analysis [mRNA-Seq] 1.2
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 1.16
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes 1.12
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 1.08
STX4 Over-Expression in Human islets 1.07
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 1.06
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 1.06
Antiviral innate immunity of hepatitis C virus-infected stem cell-derived hepatocytes 1.06
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 1.04
RNA-seq of ASXL2 shRNA KD in SKNO-1 cells 1.02
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 1.0
Hepatic transcriptome of pediatric hepatoblastoma. 1.0
Downregulation of DDX5/DDX17 and REST 0.98
Development of an In Vitro Human Liver System for Interrogating Non-Alcoholic Steatohepatitis 0.96
Synectin Promotes Fibrogenesis by Regulating PDGFR Isoforms Through Distinct Mechanisms 0.95
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 0.94
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 0.94
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 0.93
Tracing the first hematopoietic stem cell generation in human embryo by single-cell RNA sequencing 0.92
ENCODE Cold Spring Harbor Labs Long RNA-seq 0.88
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 0.87
Kidney compartment specific eQTL studies highlight causal genes and pathways for renal disease development 0.87
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.86
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.86
Discovery and verification of liver cancer marker genes and variable scission based on second-generation sequencing data analysis 0.86
Gene expression regulated by CSA and CSB in neuroblastoma cell line 0.86
Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes 0.83
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma 0.81
Primate-specific gene TMEM14B promotes cortical expansion and folding 0.77
RNA-Seq gene profiling comparison from human cDC subsets and pre-cDC subsets 0.77
Gene Expression Profile of human hepatocellular carcinoma by RNA sequencing 0.75
Human muscle-derived CLEC14A-positive cells regenerate muscle independent of PAX7 0.75
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 0.69
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 0.68
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML [RNA-Seq human] 0.66
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML 0.66
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 0.65
Gene Expression Signature in Adipose Tissue of Acromegaly Patients 0.64
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 0.63
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes [RNA-seq] 0.62
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes 0.62
Concomitant BCORL1 and BRAF mutations in vemurafenib-resistant melanoma cells 0.59
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 0.59
Transcriptome analysis of BAP1 knockout and restoration 0.59
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 0.56
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells 0.56
Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic β-cell death 0.56
Human Treg IFNg/IL-10 subpopulations 0.55
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 0.54
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] 0.54
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [H1 RNA-seq] 0.52
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 0.51
A single-cell transcriptome atlas of the human pancreas 0.51
Interferon receptor signaling pathways regulating PD-L1 and PD-L2 expression 0.51
0.51
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 0.5
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 0.5
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 0.49
Next generation sequencing of advanced non-castrate prostate cancer treated with docetaxel chemotherapy 0.48
An integrative analysis of non-coding regulatory DNA variations associated with autism 0.46
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.45
Transcriptome profiling of HepG2 cells upon treatment of the menin-MLL inhibitor MI-503 or DMSO 0.44
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 0.41
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 0.4
Next generation sequencing of small RNAs isolated from exosomes in human semen 0.39
Proteomics identifies a marker signature of MAPKi resistance in melanoma 0.33
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism: Liver RNA profiles of lean non-diabetic, obese non-diabetic as well as obese diabetic humans. 0.33
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. 0.33
Alagille_Nodder 0.33
RNA Seq of Alagille liver biopsies 0.33
High-resolution comparative analysis of great ape genomes 0.31
Muscle transcriptome analysis following Total Knee Arthroplasty with Tourniquet 0.3
Genes altered in expression by Cisplatin treatment in lung cancer cell lines 0.29
IKZF1 as a Master Regulator of Immune Infiltrate Recruitment in Solid Tumors 0.29
CRISPR-Cas9 based screen for p53-bound enhancers that function in oncogene-induced senescence 0.25
Transcriptional profiling of LS1034 cells treated with tepoxalin 0.25
JAK dependent survival of ALK- ALCL 0.22
Gene expression profiling of patient's DCIS-IDC tandem lesions by RNA sequencing analysis 0.22
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (BGI12 RNA-Seq) 0.21
Radiation enhances melanoma response to immunotherapeutic and synergizes with benzodiazepines to promote improved anti-tumor activity 0.21
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 0.19
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 0.18
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 0.18
Interleukin-1β induces mitochondrial DAMP production to activate STING-dependent innate immune programs 0.16
Alteration of the microRNA network during the progression of Alzheimer’s disease 0.15
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 0.14
RNAseq of CD8+ and CD8- MAIT cells in human peripheral blood 0.14
Preclinical model of obesity and ER-positive breast cancer 0.13
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 0.13
RNA-Seq and expression data from human adipose tissue 0.12
Tissue-specific RNA-seq in human evoked inflammation identifies novel blood and adipose lincRNA signatures of cardio-metabolic diseases 0.12
Gene expression profile of melanoma cell lines after overexpression or knockdown of KPC1 0.11
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 0.1
Hepatocyte maturation 0.09
Gene expression profiles of isogenic single-cell derived clones of BRAF-mutated SK-MEL-5 melanoma cell lines 0.07
Discovering human diabetes-risk gene function with genetics and physiological assays 0.06
Genes encoding cognate receptors for IRI-related recipient cytokines are expressed in donor livers 0.04
Single-cell ID-seq identifies BMP signaling as a driver of a late stage epidermal differentiation program. 0.04
Effect of BMP inhibition or stimulation of primary human keratinocytes 0.04
Transcriptional dependencies in diffuse intrinsic pontine glioma 0.03
RNA-Seq of polysome profiling fractions and whole cell lysates of UVB-irradiated N-TERT keratinocytes 0.02
Increased Neanderthal ancestry in genomic regions associated with lipid catabolism in contemporary Europeans 0.01


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