Gene Query: SAT1

Dataset Description Geneva Score
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 169.07
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 169.07
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte [RNA-seq] 128.95
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte 128.95
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 120.8
Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy 109.97
Paxillin regulates genomic networks in prostate cancer [C4-2] 96.11
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 93.1
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia (RNA-seq) 92.05
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia 92.05
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 89.26
Self-organization of polarized cerebellar plate neuroepithelium in three-dimensional culture of human pluripotent stem cells 88.28
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 85.96
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes 85.1
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes (RNA-seq) 85.1
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 83.81
UBC9 knockdown in bladder cancer T24 cell lines 83.47
FOXD3 is a novel tumor suppressor in lung cancer 83.43
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 83.06
RNA sequencing analysis of human embryonic stem cells and axial progenitors 83.04
Transcriptional change of THP-1 after HSV-1UL37WT or HSV-1UL37C819S 82.9
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 82.79
Expression analysis of Mebendazole treated THP-1 cells in three paired samples 82.75
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 76.22
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 76.22
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not 75.45
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 73.01
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 72.52
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 71.54
Cajal bodies are linked to genome conformation 70.14
Cajal bodies are linked to genome conformation [RNA-Seq] 70.14
Crizotinib v. DMSO in SW480 cells 68.12
Effect of BB608 on Gene Expression in HNSCC Cell Line 67.51
The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis 67.28
Trnascriptome analysis of HeLa cells infected with rTHOV-wt, -dML, -SW mutant or mock-treated 66.86
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 66.63
A transcriptome-wide divergence in protein translation scales with LIN28B expression 64.95
Lineage specific differentiation is influenced by state of human pluripotency [RNA-seq] 62.56
Lineage specific differentiation is influenced by state of human pluripotency 62.56
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 61.74
Rational targeting of cooperating layers of the epigenome yields enhanced therapeutic efficacy against AML 61.29
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 61.24
RNAseq analysis of ESRP regulated splicing events in prostate cancer 60.89
RNA-seq of human foreskin fibroblast cells lacking RB and/or p130 after doxorubicin treatment 59.11
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 58.46
RNASeq of 4SU labelled nascent RNA in MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 58.43
CD95/Fas ligand mRNA is toxic to cells 57.94
Exploring transcriptomic landscapes in red cell populations, in their extracellular vesicles and on single cell level 57.79
Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium 57.73
High-Throughput Drug Screening identifies Pazopanib and Clofilium tosylate as effective treatments for malignant rhabdoid tumors 57.65
Transcriptome analysis in Neobractatin treated cells 56.12
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 55.33
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 53.69
Stably-paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor Triptolide 53.66
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells 53.51
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells [RNA-seq] 53.51
Leukodystrophy-associated POLR3A mutations down-regulate the RNA polymerase III transcript and important regulatory RNA BC200 53.51
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype 51.87
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype [RNA-Seq] 51.87
Effects of Polybrominated Diphenyl Ether (PBDE) Mixture on estrogen receptor positive (ER+) patient-derived tumor xenograft (PDX) model 51.33
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 50.23
STRIPAK directs PP2A activity to promote oncogenic transformation 49.94
Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation 49.52
RNA-Seq from early time points in the kidney differentiation protocol 49.48
Differential gene expression in Jagged1 treated human dental pulp cells. 49.19
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 48.56
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 47.79
Gene expression data from IMR90 control, IMR90 shRRM2 and shRRM2/shp16 47.19
Combined use of astragalus polysaccharide and berberine attenuates insulin resistance in IR-HepG2 cells via regulation of the gluconeogenesis signaling pathway 46.69
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 46.63
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 46.63
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 46.58
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 46.58
RNA-seq of human aneuploid cell lines with Trisomy 21 46.28
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 45.82
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 45.63
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 45.2
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 45.11
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 45.01
Tamoxifen Resistance in Breast Cancer is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis 44.51
CpG dinucleotides introduced into gag can inhibit HIV-1 gene expression by modulating pre-mRNA splicing 44.27
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 43.64
Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells 43.42
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 43.28
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 [RNA-seq] 43.16
Genes directly regulated by NF-κB in human hepatocellular carcinoma HepG2 43.16
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer 43.1
Transcriptome profiling of a mouse model of alveolar soft part sarcoma 42.57
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells 41.36
RNA-seq analysis of A498 cell line treated with siSETD2 or si-NC 41.29
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 40.23
Gene expression by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1.4 knock-down and multiple H1 variants 39.69
Resistance to BET inhibitor leads to new therapeutic vulnerabilities in castration resistant prostate cancer 39.66
Depicting early human development and germ cell origin with porcine embryos 39.39
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 39.32
Improved genome-wide mapping of uncapped and cleaved transcripts in eukaryotes—GMUCT 2.0 39.04
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 38.76
SUV420H2 knockdown in PANC-1 38.54
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 38.5
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (ChIP-seq & RNA-seq datasets) 38.44
AUF-1 affected genes in human skin cells 37.89
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 37.85
RNA-Seq analysis of breast cancer cells after shikonin treatment 37.83
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons 37.77
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons [RNA-seq] 37.77
RNA-seq of shEZH2 cells 37.75
Peptidomimetic blockade of MYB in acute myeloid leukemia 37.56
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 37.56
Extracellular matrix hydrogel derived from decellularized tissues enables endoderm organoids culture 37.46
Response of HEK293 Freestyle cells to 36 h of culture in Zn(II)-depleted Freestyle medium 37.31
Single-nucleotide-resolution mapping of HBV promoters using CAGE 37.27
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 37.21
Sequencing of freshly produced RNA following exposure of cells to DNA damage-inducing UV mimetic 4-hydroxyaminoquinolone (4-NQO) 37.17
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 37.04
Limiting cholesterol biosynthetic flux engages type I IFN signaling in a STING-dependent manner 37.04
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination 37.01
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 36.89
Allogeneic mature human dendritic cells generate superior alloreactive regulatory T cells in the presence of IL-15 36.57
Transcriptomic profiling of human coronary artery endothelial cells under laminar shear stress (LS), oscillatory shear stress (OS) and static culture (ST) 36.46
Generation of induced neural stem cells from urine derived cells by synthetic mRNA 36.38
Ribosome profiling and RNA sequencing of MCF10A-ER-Src and fibroblast cell transformation 36.22
Transcriptomic analysis of trametinib-resistant HCT116 colorectal carcinoma cells compared to the parental control cells 36.03
Gene expression analysis of C4-2 cells treated with ACLY inhibitor and Enzalutamide 35.58
Total RNA sequencing of prospective axial stem cell cultures derived from human pluripotant stem cells 35.56
METTL3 promotes translation in human cancer cells 35.38
Tracking of dCas9-methyltransferase footprints 35.28
Knockout of miR-221 and miR-222 reveals overlapping and specific function between paralogous miRNAs 35.19
Contribution of SRF and Nkx2-5 to androgen-dependent gene expression in prostate cancer 35.02
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 34.92
Transcripotome analysis of different locations of hair follicles (bulb, bulge) in androgenetic alopecia 34.81
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells 34.51
Large-scale epigenetic reprogramming is punctuated late during the evolution of pancreatic cancer progression 34.49
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 34.31
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 34.31
miR941 overexpression experiment 34.3
Gene expression analysis of the impact of TDP-43 knockout in human cells. 34.22
ChIP-seq of ER and RUNX2 in MCF7 breast cancer cell lines 34.06
Differential Gene Expression between MCF10A and MCF7 cells 33.95
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 33.84
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 33.81
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [HCT RNA-Seq] 33.74
mRNA-seq from Nutlin-3a, doxorubicin, and DMSO treated HCT116 p21-/- cells 33.36
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 33.33
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 33.19
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 32.92
A sister of NANOG regulates genes expressed in pre-implantation human development 32.9
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 32.9
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 32.72
Single-cell analysis reveals stochastic regulation of type I IFN production by plasmacytoid dendritic cells and identifies host-derived environmental cues as amplifier of type I IFN production 32.62
The landscape of alternative splicing in aggressive prostate cancers 32.61
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 32.51
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 32.5
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NfkB-dependent differentiation of AML cells 32.11
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 32.1
Replicated transcriptome profiling of Normal and Cancerous Prostate Cells [RNA-Seq] 32.03
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations [RNA-seq] 32.02
Three-dimensional disorganisation of the cancer genome occurs coincident with long range genetic and epigenetic alterations 32.02
Essential Roles of SETD7 as Transcriptional Activator and Co-regulator of H3K36me in Cardiac Lineage Commitment 31.86
RNASEQ Analysis of sh-TRC and sh-MIR100HG in the triplex negative breast cancer 31.77
FOXP1 orchestration of ASD-relevant signaling pathways. 31.77
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 31.7
Effects on gene expression of ibrutinib treatment in human stem cells-derived atrial- and ventricular-like cardiomyocytes 31.45
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (LNCaP RNA-seq) 31.36
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 31.34
Genes regulated by SPDEF or FOXA3 in A549 lung carcinoma cells [RNA-seq] 31.34
Studying the selectivity of a targeted small molecule degrading a hypoxia-associated non-coding RNA 31.21
Maturation of human iNSCs 31.06
Dtx3L and Androgen Signaling in Prostate Cancer 30.84
Single-cell transcription profiling in KS1 patient iPSCs and NPCs 30.7
Genome-wide view of the impact of Spt5-Pol II inhibitors (SPIs) on mRNA levels [RNA-Seq 2h] 30.52
MicroRNA-125a-5p overexpression in human macrophages 30.47
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program 30.42
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program (RNA-Seq) 30.42
mRNA Sequencing of Human PromoCells Using 3'-directed Digital Gene Expression (3'-DGE) Technique 30.38
XBP1s Activation Globally Remodels N-Glycan Structure Distribution Patterns 30.29
SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 30.28
mRNA sequencing identifies differential gene expresssion profiles between ASCC3 knock-down cells and control cells 30.26
transcriptome studies of BRD4 inhibitor BDF-1253 on renal clear carcinoma 786-O cells 30.2
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells 30.13
Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells. [RNA-Seq - ex vivo] 30.12
Tricyclic Antidepressants Induce Inactivation of Hepatic Stellate Cell (HSC) Myofibroblasts 30.02
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation [RNA-seq] 29.94
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation 29.94
The dynamic landscape of coding and non-coding RNAs in the innate immune response to microbial pathogens 29.86
Consequences of Ribosomal Protein Haploinsufficiency in Human Hematopoiesis 29.86
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 29.82
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 29.75
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 29.74
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 29.72
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 29.63
CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells 29.53
The Human Testis Cell Atlas via Single-cell RNA-seq (Healthy men scRNA-seq data set) 29.32
Identification of the RB loss-induced transcriptome and E2F1 cistrome in prostate cancer 29.18
Identification of the RB loss-induced transcriptome in prostate cancer [RNA] 29.18
Identification of differential expressed genes of JQ1 or JQ1+Bortezomib in colorectal cancer cells 29.18
Differential expression of long non‑coding RNA and mRNA in children with Henoch‑Schönlein purpura nephritis 29.17
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 29.16
The ribonuclease activity of SAMHD1 is required for HIV-1 restriction 29.06
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 29.03
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1 28.93
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 28.82
Genome-wide analysis of STAT3 in diffuse large B-cell lymphoma 28.75
Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells 28.75
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation I 28.74
Improved post thaw function and genetic changes for mesenchymal stromal cells cryopreserved using multicomponent osmolyte solutions 28.61
Transcriptional profiling of MCF7 cells treated with H3B05942, E2, or standard of care compounds 28.55
Lung Cancer Cell-Mediated Skeletal Muscle Mitochondrial Dysfunction is Mitigated by 1a,25-Dihydroxyvitamin D3 28.49
Analysis by Whole Transcriptome Sequencing of the Effects of LLC1 conditioned medium, LLC1 conditioned plus Calcitriol, non-conditioned medium, and non-conditioned medium plus Calcitriol on mRNA Expression in Primary Human Skeletal Muscle Cells 28.49
Transcriptional impact of MTHFD2 in Human Aortic Endothelial Cells 28.43
A peninsular structure coordinates asynchronous differentiation with morphogenesis to generate pancreatic islets [bulk vs buds] 28.43
Recruiting Endogenous ADARs with Antisense Oligonucleotides to Reprogram the Transcriptome 28.29
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability 27.75
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (22RV1 RNA-seq) 27.75
WRN knockout effects upon gene expression in SW48 and OVK18 27.69
In vivo genome editing restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers 27.67
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 27.6
FBXW7 modulates stress response by post-translational modification of HSF1 27.6
KLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the bone 27.52
hnRNP C is a key regulator of protein synthesis in mitosis 27.42
Telomere-Dependent and Telomere-Independent Roles of RAP1 in Regulating Human Stem Cell Homeostasis 27.31
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 27.28
Effect of ILF3 on translation during homeostasis and the antiviral response 27.27
Polarized B -cell functions 27.26
mRNA Sequencing of Human PromoCells Using Random Primed mRNA-Sequencing Technique 27.04
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 27.02
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 27.02
Irf9 function in immunity in mouse 26.98
Transcription profile analysis of wild type and Irf9-/- human monocytic THP1 cells in response to type I interferons 26.98
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 26.92
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 26.92
Paxillin regulates genomic networks in prostate cancer [LNCaP] 26.68
Steroid Receptor Coactivator-2 Regulated Transcriptome in Human Endometrial Stromal Cells 26.65
Identification of Sin3B regulated genes during quiescence 26.33
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq Human] 26.11
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 25.92
Long non-coding RNA TYKRIL controls pericyte function and survival in the cardiovascular and central nervous system through regulation of p53 activity and PDGFRß expression 25.85
Stimulation of isolated plasmacytoid dendritic cells (pDCs) with TLR9 agonist CpG C (CpG) and TLR7 agonist imiquimod (IMQ) 25.78
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 25.75
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 25.75
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance 25.74
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq) 25.74
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on HepG2) 25.53
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 25.13
Enriched EWSR1 and EWS-FLI1 RNA-seq of HNRNPH1-silenced TC32 Ewing sarcoma and 293T human embryonic kidney cells. 25.0
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 24.96
RNA sequencing (RNA-SEQ) of Human endothelial cells (HUVEC) in LFS, sFRP2OE, and WT conditioned media 24.79
Nuclear HNRNPA2B1 HITS-CLIP and RNA-seq 24.73
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 24.66
Ebola virus (EBOV) infection of ARPE-19 cells 24.5
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 24.49
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 24.48
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 24.48
Global expression profiles in cardiac progenitor cells generated by ISX-9 24.4
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 24.4
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer 24.33
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer [RNA-Seq] 24.33
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 24.3
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 24.3
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 24.18
Prediction of bacterial infection outcome using single cell RNA-seq analysis of human immune cells [sorted population Bulk RNA-seq] 24.01
Circular RNA expression signature of low-glucose-treated MIA PaCa-2 cells 23.91
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation 23.84
Assembly of methylated LSD1 and CHD1 drives AR-dependent transcription and translocation [RNA-Seq] 23.84
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 23.81
Transcriptome profiling of Normal and Cancerous Prostate Cells 23.78
MYCi361 regulates MYC target genes 23.72
RNA-seq data from human SGBS adipocytes differentiated with marine oxohexadecenoic acids 23.48
Human iPSC derived glomeruli facilitate accurate modelling of podocytopathy 23.28
Gene expression in control and DOCK8 CRISPR KHYG1 NK cells 23.24
Diverse Compounds from Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis 23.03
Cell-specific expression and function patterns of microRNA-150-5p in liver fibrogenesis 22.92
RNA seq with AML (NB4) cells upon FTO inhibition 22.71
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies 22.65
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies [RNA-Seq] 22.65
Profiling and bioinformatics analyses reveal differential expression of circular RNA in tongue cancer revealed by high-throughput sequencing 22.6
Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition 22.54
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 22.48
Transcriptomics analysis of human jejunal enteroendocrine cells after vertical sleeve gastrectomy 22.42
Transcriptomics analysis of enteroendocrine cells following vertical sleeve gastrectomy 22.42
Generation of trichogenic adipose-derived stem cells by expression of three factors 22.38
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [polyA RNA-seq] 22.37
Tracking distinct RNA populations using efficient and reversible covalent chemistry 22.36
The DNM3OS lncRNA is a reservoir of fibromiRs with major functions in fibroblast response to TGF-beta and fibrogenesis 22.28
RNA-Seq analysis of human lung fibroblasts exposed to TGF-β 22.28
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes 22.28
Detailed genomic and molecular characterization of Indian induced pluripotent stem cell lines 22.19
Adaptive chromatin remodeling in glioblastoma stem cell plasticity and drug tolerance 22.16
Evolution of a transcriptional regulator from a transmembrane nucleoporin 22.06
RNA-seq in HepG2 and IMR90 cells 22.06
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 21.91
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 21.89
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 21.86
The ARID1A tumor suppressor controls global transcription via pausing of RNA Polymerase II 21.85
SF3B1 Degron knockdown RNA-seq 21.49
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export II 21.28
Genome-wide RNA-seq from GALNT14-depleted and GALNT14 overexpressing MDA-MB-231 LM2 and Par cells 21.25
Transcriptome Analysis of PBMCs in peripheral blood of patients with hepatocellular carcinoma 21.14
RNA-seq analysis of BAP1-depleted uveal melanoma cells 21.02
Effect of nuclear IL-33 on gene expression 20.99
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 20.87
Regionally specified human pluripotent stem cell-derived astrocytes 20.76
MEIS1 regulates hematopoiesis in hPSCs 20.76
Next Generation Sequencing Facilitates Quantitative Analysis of human patient derived primary Glioblastoma (GBM) cancer cell Transcriptomes 20.58
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 20.48
RNASeq of mouse, human, and non-human primate primary dermal fibroblasts to poly(I:C) transfection 20.35
Cell responses to dysregulated VZV-induced cell-cell fusion 20.16
Targeting JNK Pathway Expands Human Hematopoietic Stem Cells 20.15
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 20.05
RNA sequencing of CACO-2 cells incubated with Bifidobacteria breve grown on human milk oligosaccharides. 20.01
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 19.9
Epigenomic plasticity enables human pancreatic alpha to beta cell reprogramming 19.88
U2AF1 mutations alter splice site recognition in hematological malignancies 19.76
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 19.38
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 19.38
Identification of renal resident macrophages across species [C1] 19.34
Distinct changes in transcriptional profiles and epigenetic patterns mediated by EZH2 inhibitors in sensitive and insensitive prostate cancer cells 19.23
EZH2 inhibitor-mediated transcriptional profiling in prostate cancer cells [RNA-seq] 19.23
Whole Transcriptome RNASeq Data for Cell-Sorted Antibody Secreting Cells (ASC) 19.14
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 19.1
Non-synchronized cell cycle transcriptomics in U2OS and HeLa cancer cells 18.99
Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells 18.6
Gene expression changes upon drug withdrawal (Mel888 cell line) 18.55
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 18.53
Human Pancreatic Islets Expressing HNF1A Variant Have Defective β cell Transcriptional Regulatory Networks 18.44
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 18.38
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  18.27
Genome-wide expression profiling of B Lymphocytes reveals IL4R increase in allergic asthma 18.19
Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation 18.14
RNA-Sequencing of HUVEC treated with Tie2 activating antibody 17.98
Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation 17.96
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 1) 17.84
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal 17.83
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal [RNA-Seq] 17.83
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 17.75
Transcriptome analysis of BAP1 knockout and restoration 17.69
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 17.69
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 17.58
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 17.58
LncRNA NMR knockdown and overexpression in esophageal squamous cell carcinoma cell lines 17.58
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 17.56
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 17.51
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 17.51
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 17.49
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 17.49
Genome-wide DNA accessibility maps and differential gene expression using ChIP-seq, ATAC-seq and RNA-seq for the human secondary fibroblast cell line hiF-T and whole worms with and without knockdown of FACT complex 17.1
Characterization of parental and rociletinib-resistant derived H1975 cell lines 16.92
DRB/GRO-Seq -/+ UV 16.51
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 16.41
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 16.41
Integrative vascular endothelial cell genomics identify AIDA as a coronary artery disease candidate gene (RNAseq) 16.36
Integrative vascular endothelial cell genomics identify AIDA as a coronary artery disease candidate gene 16.36
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 16.36
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 16.12
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 16.12
Molecular mechanism underlying increased ischemic damage in the ALDH2*2 genetic polymorphism using a human iPSC model system 16.02
DAOY-NERT2 Notch/Hypoxia Transcriptome Analysis 16.0
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HET] 15.92
Effects of plasticizers (bisphenol A, bisphenol AF) and an herbicide in MCF7 human breast cancer cells 15.87
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 15.82
TAF1 is critical for AE driven leukemogenesis 15.75
TAF1 is critical for AE driven leukemogenesis [RNA-seq] 15.75
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 15.69
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 15.51
CDK4/6 inhibitor resistance in prostate cancer 15.49
Transcriptional Signatures of Hypoxic and Inflammatory Renal Epithelial Injury 15.46
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 15.2
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens 15.05
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens [RNA-Seq] 15.05
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 14.93
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 14.93
Identification of HOXB13 target genes responsive to BET inhibitors 14.88
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 14.69
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes [seq] 14.63
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes 14.63
Silencing p300 in MCF7 cells to study expression and alternative splicing 14.5
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 14.47
Gene expression changes in human melanoma cell lines compared to primary melanocytes 14.26
Expansion of adult human pancreatic tissue yields organoids harbouring progenitor cells with endocrine differentiation potential 14.24
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy 14.08
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy [RNA-Seq] 14.08
Gene expression profile in FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA using RNA-seq. 14.05
FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA 14.05
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 13.74
A novel target of EZH1/2 for treatment of mantle cell lymphoma 13.71
Epidermal growth factor activates β-catenin via integrin-linked kinase to control proliferation of mesenchymal stromal cells. 13.54
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 13.52
A map of gene expression in neutrophil-like cell lines 13.31
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 13.3
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 13.27
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 13.15
Radiomic and gEnomic approaches for the enhanced DIagnosis of REnal Cancer (REDIRECt): A translational pilot study 13.1
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 12.98
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 12.98
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 12.87
mRNA sequencing of the global effect of SOX2 on gene expression in hESC and hESC derived NPCs. 12.87
Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models 12.86
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 12.77
Genome-wide transcriptional response to random aneuploidy in human cells 12.69
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 12.25
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 12.25
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner 12.23
KSHV vIRF3 promotes angiogenesis of lymphatic endothelial cells (LECs) 12.12
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 12.1
Identification of miR-100 and miR-125b targets by AGO2 RIP-seq and RNA-seq after ectopic expression of miR-100 or miR-125b and evaluation of the TGFb expression signature in PANC-1 cells by RNA-seq 11.91
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes 11.8
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes [RNA-seq] 11.8
Next generation sequencing of small RNAs isolated from exosomes in human semen 11.79
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 11.69
ARS2 is a general suppressor of pervasive transcription [RNAseq] 11.33
Comparative gene expression profiling of human primary endotheliocytes cultivated on polyurethane-based electrospun 3D matrices and natural decellularized vein 11.03
GATA2 promotes hematopoietic development and represses cardiac differentiation of human mesoderm 11.02
Vammin induces a highly efficient angiogenic response through VEGFR-2/NRP-1 and bypasses the regulatory function of VEGFR-1 10.95
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 10.88
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 10.88
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 10.87
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 10.87
β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells 10.83
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 10.37
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 10.29
H3K27ac ChIP-Seq and mRNA-Seq analysis of five human B-lymphoblastoid cell lines (LCLs) prepared from the same healthy male individual (CEPH/UTAH). 10.2
FOXO1 is required for binding of PR on IRF4, novel transcriptional regulator of endometrial stromal decidualization 9.75
Progesterone receptor transcriptome and cistrome in decidualized human endometrial stromal cells 9.75
Progesterone Receptor- and FOXO1-dependent transcriptomes decidualized human endometrial stromal cells 9.75
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 9.35
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 9.3
Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains 9.21
Dual RNA-seq – High-resolution comparative Dual RNA-seq time-course 9.21
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 9.21
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 9.21
RNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation 8.94
JQ1 +/- Vemurafenib in BRAF mutant melanoma (A375) 8.91
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 8.84
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 8.82
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 8.82
FOXA1 Chromatin Binding is Regulated by LSD1-Mediated Demethylation 8.75
RNA-Seq with DHT induction and/or GSK treatment at 24, 48 hrs and 2 weeks 8.75
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 8.75
Quantitative analysis of bi-modal binding of BET proteins at promoters predicts I-BET sensitivity 8.56
CDK12 mediated transcriptional regulation in U2OS cells 8.24
A histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing 7.92
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 7.88
Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and Natural Killer Cell Function 7.22
Differences in miRNA Detection Levels are Technology and Sequence Dependent 7.07
Differences in miRNA Detection Levels are Technology and Sequence Dependent [NGS] 7.07
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 6.79
Effect of ILF3 depletion in HeLa cells on RNA steady state levels 6.73
mRNA sequencing of the mouse and human Hep-Orgs, Chol-Orgs and primary hepatocytes 6.59
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples 6.53
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 6.51
Transcription factors and stress response gene alterations in human keratinocytes following Solar Simulated Ultra Violet Radiation 6.47
Identification of renal resident macrophages across species 6.47
Similarity of therapeutic networks induced by a multi-component herbal remedy in neurovascular unit cells 6.33
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 6.16
Widespread regulated alternative splicing of single codons accelerates proteome evolution 6.13
Muscle transcriptome analysis following Total Knee Arthroplasty with Tourniquet 6.12
Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells 6.01
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L 6.0
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 5.94
Aneuploidy-induced cellular stresses limit autophagic degradation. 5.78
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 5.5
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 5.5
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 4.6
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 4.49
Effect of SHP2 inhibition on hepatic stellate cell transcriptome. 4.44
Regulators of cellular heterogeneity in basal-like breast cancer influence symmetric versus asymmetric division rates (shRNA targeting) 4.16
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 4.05
The bromodomain protein BRD4 regulates splicing during heat shock 4.0
Sirt6 Oncogene Mediates PI3K/Akt Signaling Activation in Diffuse Large B-Cell Lymphoma 3.81
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 3.81
RNA-Seq analysis of prostate cancer cell line LNCaP treated with vehicle, androgen, androgen and IMTPPE, androgen and JJ-(+)-450, androgen and JJ-(-)450, androgen and enzalutamide 3.51
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 3.49
RNA-seq and ChIP-seq analysis of BMI1 or RING1B-silenced prostate cancer cells C4-2 3.34
Immune Checkpoint Regulation of Pulmonary Fibrosis [bulk RNA-seq] 3.18
Temporal comparison of transcriptomic alterations in human, mouse and rat primary B lymphocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) 3.09
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 2.91
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 2.91
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 2.82
MRTF activates TEAD-YAP target gene expression 2.74
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 2.67
Organelle-based therapy for immune mediated disease: mitochondrial transfer elicits Tregs reprogramming 2.59
IMP3 regulated gene expression in breast cancer cells 2.54
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency 2.54
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency [RNA-Seq] 2.54
Genome-wide transcriptome analysis of organotypic rafts derived from human papillomavirus type 16 infected primary keratinocytes [3D raft] 2.48
DAOY-Notch1/Notch2 knockout: transcriptome comparison 2.46
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ super-enhancers 2.46
RNA-sequencing of the human milk fat layer during colostrum, transitional, and mature stages of lactation 2.2
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 1.84
RNA-seq of human foreskin fibroblast cells lacking RB, p130, and p107 treated with doxorubicin. 1.5
mRNA-Seq profiling SIX2+ and Foxd1+ cells in mouse embryonic and SIX2+ and SIX2-/MEIS1+ cells human fetal kidney 1.28
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 1.24
HNRNPM-regulated splicing dependencies in prostate cancer [RNA-Seq] 1.19
HNRNPM-regulated splicing dependencies in prostate cancer 1.19
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 1.16
Proteomics identifies a marker signature of MAPKi resistance in melanoma 1.09
Frailty in middle age is associated with race-specific changes to the transcriptome. 0.81
RNA expression profiles comparing primary and omental ovarian carcinoma samples 0.68
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (scRNA-Seq) 0.51
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 0.16
FOXP3 protects conventional human T cells from premature restimulation-induced cell death 0.08


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