Gene Query: SERPINB2

Dataset Description Geneva Score
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells 273.8
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 253.44
UBC9 knockdown in bladder cancer T24 cell lines 250.33
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 220.91
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest 209.61
KLF4 as a rheostat of osteolysis and osteogenesis in prostate tumors in the bone 196.53
ZIKV infection of monocytes activates inflammasome pathways 195.19
Genome-wide transcriptional response to random aneuploidy in human cells 194.81
Next generation sequencing of human hepatic stellate cell line, LX-2 treated with recombinant human TGF-β1, with DMSO or ML290 (5 µM) for 72h. 194.27
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 191.28
Transcriptome-wide analysis of adipose circular RNAs reveals their dynamic regulation in obesity and functional role in adipogenesis 181.22
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 169.45
STRIPAK directs PP2A activity to promote oncogenic transformation 139.7
Transcriptome analysis of AGS cells infected with Helicobacter pylori P12 138.63
Regulation of protein translation during mitosis 138.08
RNA-seq data of adipocytes co-cocultured with OVCAR5 in Boyden chamber (4d) 133.01
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells (Poly(I:C) and LPS) 131.9
TLR2 dimerization blockade allows generation of homeostatic intestinal macrophages under acute colitis challenge 121.69
Transcriptomic profiling of human coronary artery endothelial cells under laminar shear stress (LS), oscillatory shear stress (OS) and static culture (ST) 116.42
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 114.37
Transcriptomics of human macrophages upon infection with Legionella pneumophila and two isogenic mutants, LamA and AnkH using RNA-seq 111.32
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 108.27
Genome-wide analysis of herpes simplex virus type 1 (HSV-1) infected cells 105.0
SETDB1 compacts the inactive X chromosome in part through silencing an enhancer in the IL1RAPL1 gene 98.04
Generation of trichogenic adipose-derived stem cells by expression of three factors 94.56
RNA-Seq analysis of breast cancer cells after shikonin treatment 93.38
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 89.75
Transcriptome profiling of influenza virus-infected human bronchial epithelial cells 88.44
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling 87.82
Virus-like vesicles of Kaposi’s Sarcoma-Associated Herpesvirus activate lytic replication through triggering differentiation signaling (mRNA) 87.82
RNA sequence analysis of stable versus reversible EMT events and the resultant metastases 85.32
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 83.87
RNA-sequencing (RNA-seq) in BxPC-3 and S2-007 cell lines 82.73
MYC interacts with the G9a histone methyltransferase to drive transcriptional repression and tumorigenesis 80.52
Mycobacterium bovis Bacillus Calmette-Guerin (BCG) reprograms melanoma microenvironment to promote antitumor T cell responses 78.55
Germline NLRP1 mutations cause skin inflammatory and cancer susceptibility syndromes via inflammasome activation 76.72
PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome 74.05
PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome [RNA-seq] 74.05
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 72.38
RNA-sequencing of human leukemia cells and mouse hematopoietic progenitors 71.27
Genetic and pharmacological restoration of TET2 function blocks stem cell self-renewal and progression of leukemia 71.27
JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors 70.57
RNA-Seq and ATAC-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 68.58
RNA-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 68.58
Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 63.9
Human CD11b+ macrophages - Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 63.9
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 63.14
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 62.97
CD74 role in transcription regulation 61.81
CD74 role in transcription regulation [RNA-seq] 61.81
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 61.04
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 60.85
Generation of KRAS signatures using immortalized isogenic lung cells. 60.74
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 59.75
Prediction of bacterial infection outcome using single cell RNA-seq analysis of human immune cells [sorted population Bulk RNA-seq] 58.41
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 58.12
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 55.34
Chromatin-informed inference of transcriptional programs in gynecologic cancers [RNA-Seq] 55.16
Chromatin-informed inference of transcriptional programs in gynecologic cancers 55.16
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 54.75
Transcriptional effect of ETV1 knockdown in melanoma cells 52.47
Identification of the role of polydom in neurofibromas 52.0
Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors 50.81
Aneuploidy triggers an immune response 49.69
Effect of BMP inhibition or stimulation of primary human keratinocytes 49.27
Single-cell ID-seq identifies BMP signaling as a driver of a late stage epidermal differentiation program. 49.27
Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation 47.54
Hydroxychloroquine inhibits responses to group A streptococcus in peripheral blood mononuclear cells 46.54
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes 45.27
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes (RNA-seq) 45.27
Identification of differentially expressed genes between senescence and senescence bypass cells 45.12
A pooled single-cell genetic screen identifies regulatory barriers in the continuum of the epithelial-to-mesenchymal transition 45.01
Downregulation of LATS kinases alters p53 to promote cell migration 44.95
Transcriptomic analysis of senescent cells upon EXOC7 knockdown. 44.66
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 44.52
Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols 44.46
Differential expression of genes in HCMV-infected fibroblasts regulated by the purinergic receptor P2Y2. 44.27
Transcriptomes of oxLDL exposed trained monocytes 44.16
oxLDL exposed trained monocytes 44.16
Differential susceptibility of human pleural and peritoneal mesothelial cells to asbestos exposure 43.77
Analysis of the polyA+ RNA of LPS-treated human CD14+ monocytes 43.18
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 43.02
Transcriptional change of THP-1 after HSV-1UL37WT or HSV-1UL37C819S 42.97
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 42.85
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 42.85
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 42.43
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 42.43
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 42.2
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_1A_PI3K_RNA-seq] 42.17
Reprogramming postnatal human epidermal keratinocytes toward functional neural crest fates 41.37
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer 40.82
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 40.78
Transcriptomic and gene ontology profiling of the human corneal cell types 39.23
Deletion of DXZ4 on the human inactive X chromosome eliminates superdomains and impairs gene silencing 39.07
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 38.9
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 38.9
hTERT promotes cell adhesion and migration independent of telomerase activity 38.46
Sequencing-based analyses characterize a tumor suppressive role of mir-1271 repressed by DNA hypermethylation in gastric cancer 38.37
NAPRT activation of macrophages 38.25
Cyclophosphamide (CTX) Enhances Cancer Antibody Immunotherapy in the Resistant Bone Marrow Niche by Modulating Macrophage FcγR Expression 37.99
Modulation of ESRP2 and MBNL2 in normal kidney and clear cell renal cell carcinoma cell lines for analysis of stability programs 37.6
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 37.49
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 36.89
Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells 36.86
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 36.82
Prostaglandin E2 inhibits pro-fibrotic function of human pulmonary fibroblasts by disrupting Ca2+-signaling 36.79
RNA expression following TMPRSS11B overexpression or depletion 36.77
Regulation of Lipids is Central to Replicative Senescence 36.14
Comparison of single-cell transcriptomics quality between unfixed cells and cells that were fixed and mock stained according to the RAID procedure 34.65
PTP4A1 phosphatase is overexpressed in systemic sclerosis fibroblasts and promotes TGFb signaling 34.63
RNA-seq of human foreskin fibroblast cells lacking RB, p130, and p107 treated with doxorubicin. 34.47
Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing 33.71
Molecular Mechanisms of Endothelial Hyperpermeability 33.68
6mer seed toxicity in tumour suppressive microRNAs 33.58
MiR-26 dampens IL-6 production by down-regulating TNF-a/NF-kB signaling through silencing HMGA1 and MALT1 and not by directly targeting IL-6 mRNA 33.52
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 33.03
RNASeq of mouse, human, and non-human primate primary dermal fibroblasts to poly(I:C) transfection 33.01
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure 32.83
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 32.5
Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9 32.46
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells 32.29
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells (RNA-seq) 32.29
The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells 32.25
Identification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression 32.25
Transcriptome profiles of moderate dysplasia in oral mucosa associated with malignant conversion 32.11
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas 31.88
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 31.75
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 31.75
Electronic cigarettes 31.39
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 31.3
Molecular pathogenesis of human prostate basal cell hyperplasia reveals a keratinocyte metaplasia 31.11
Integrative analysis of mRNA and lncRNA profiles identified pathogenetic lncRNAs in esophageal squamous cell carcinoma 31.07
Effect of Hotair overexpression in human breast cancer cell lines 30.82
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [RNA-seq] 30.29
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES 30.29
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 30.15
GCTM-5 positive and negative cells in pancreatic adenocarcinoma cell lines 29.82
Transcriptomes of human monocytes and monocyte-derived macrophages with or without glucocorticoid treatment 29.8
Next-generation sequencing analysis of transcriptom in gemcitabine resistant pancreatic cancer cells 29.61
Mutational landscape of splicing genes and functional consequences across 33 cancer types 29.19
Decrease in EZH2 histone methyltransferase mediates the effects of fluid shear stress (FSS) in endothelial cells 29.12
RNA Sequencing Reveals Immunosuppressive Role of Anthrax Lethal Toxin in Human Lung Epithelial and Monocytic Cells 28.58
Effect of mitochondria deficiency on senescence-associated gene expression 28.39
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 28.05
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 28.05
Poly(ADP-ribosyl)ation dependent changes in CTCF-chromatin binding and gene expression in breast cells 27.89
Expression analysis of THP1 cells following shRNA knock-down of RUVBL2 27.81
Gene expression analysis of a panel of human fibroblasts that generate an aligned (anisotropic) vs non-aligned extracellular matrix 27.61
Analysis Of The TGFb-Induced Program In Primary Airway Epithelial Cells Shows Essential Role Of NF-kB/RelA Signaling Network In Type II Epithelial Mesenchymal Transition 27.4
Transcriptome of melanoma cell lines resistant to inhibition of the MAPK pathway. 27.3
Transcriptome analysis of virus infected tissues 27.27
Expression profiling of converted and control dermal BJ fibroblasts 27.02
p63 establishes epithelial enhancers de novo at critical craniofacial development genes 27.02
RNA-seq of cells with TET1 knockout 26.98
Epigenomes and Transcriptomes of human monocytes from Hyper IgD Syndrome (HIDS) patients 26.93
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 26.72
Effect of nuclear IL-33 on gene expression 26.67
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 26.47
In vivo genome editing restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers 26.41
Control of gene expression in senescence through transcriptional read-through of convergent protein-coding genes 26.33
Dermal endothelial cells of type 2 diabetic patients 26.31
CD97 is a Critical Regulator of Acute Myeloid Leukemia Stem Cell Function 26.29
Race-specific transcriptome and Long non-coding RNA of ADT-resistant African-American prostate cancer cell models. 25.43
Long Non-coding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity 25.39
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 25.23
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 25.23
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 25.01
Viral infection enhances NK cell activation via Type I dependent pathways and can be utilized to enhance influenza-specific monoclonal antibody therapies 25.01
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 24.51
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 24.51
RNA sequencing of human fibroblasts after SUPT4H1 siRNA treatment 24.13
RNA-seq of MCF10A cells and CAF 23.81
Expression by CD133+ cells isolated from the adult human exocrine pancreas 23.8
Tricyclic Antidepressants Induce Inactivation of Hepatic Stellate Cell (HSC) Myofibroblasts 23.77
Study of dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest 23.44
RNA sequencing for lncRNA, miRNA and mRNA expression analysis in human laryngeal cancer 23.41
Next generation sequencing on knockdown of AC093323.3 in lung cancer cells 23.16
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 22.87
CD1c+ dendritic cell activation by Plasmodium falciparum-infected red blood cells 22.16
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 22.15
Transcriptome changes due to nuclear penetration of cancer extracellular vesicles 22.1
Transcriptome-wide analysis to determine miR-200a targets in melanoma cell lines 22.04
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 21.65
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 21.53
Whole transcriptome splicing analysis in isogenic lung epithelial and adenocarcinoma cell lines with or without a recurrent splicing factor mutation, U2AF1 (S34F) 21.5
Immune Checkpoint Regulation of Pulmonary Fibrosis [bulk RNA-seq] 21.38
Gene expression profiling of human MSC-educated macrophages vs. classical macrophages from bone marrow and blood 21.37
RNA-seq of cancer-associated fibroblasts (CAF) treated with PBS or extracellular vesicles (EV) from MCF10A or MDA-MB-231 cells 21.34
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells 21.18
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells [RNA-Seq] 21.18
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 21.04
RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express either ER or ER-SOX4 with and without 4-OHT to induce nuclear translocation 20.82
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 20.7
Quantitative Analysis of negative control and overexpression-TRIB1 in PC3 and DU145 Transcriptomes 20.63
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell 20.23
RNA-Seq and ChIP-Seq reveals SQSTM1/p62 as a key mediator of JunB suppression of NF-kB-dependent inflammation 20.16
JunB control of keratinocyte-mediated inflammation [RNA-seq] 20.16
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis [RNA-seq] 20.09
Immune-restricted epigenetic reader SP140 maintains macrophage identity and activation states critical to intestinal homeostasis 20.09
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 20.0
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation [RNA-seq] 19.97
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation 19.97
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 19.66
Global transcriptional profiling changes upon knockdown of LKB1 in human glioblastoma cell lines 19.56
ZRANB2 and SYF2 mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin 19.4
CDK12 regulates alternative last exon mRNA splicing and promotes invasion of a breast cancer cell line 19.39
Epigenome regulation during epidermal lineage commitment [ATAC-seq, RNA-seq] 19.28
An in vitro human liver model by iPSC-derived parenchymal and non-parenchymal cells 19.15
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition [CAGE] 19.07
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition 19.07
RNAseq to determine gene expression changes following depletion of SETDB1 in THP-1 AML Cells 19.07
Differentially Expressed Genes upon Knockdown of ZRANB1 or EZH2 in LM2 Cells 19.05
RNA sequencing of erythroid and granulomonocytic colonies differentiated from transduced bone marrow CD34+ cells expressing U2AF1 S34F mutation, U2AF1 wild-type or empty vector control 18.96
miRNA-1343 attenuates pathways of fibrosis by targeting the TGF-beta receptors [RNA-seq] 18.67
RNA-Seq analysis of NKX2.2 knockdown in human pancreatic islets 18.61
NKX2.2 18.61
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 18.57
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 18.57
Toxoplasma gondii remodels the cis-regulatory landscape of infected human host cells [RNA-seq] 18.55
Toxoplasma gondii remodels the cis-regulatory landscape of infected human host cells 18.55
A Basal Stem Cell Signature Identifies Aggressive Prostate Cancer Phenotypes 18.52
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP 18.5
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma [RNA-seq] 18.44
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma 18.44
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 18.43
RNAseq of quiescent (Q) and stress induced premature senescent (SIPS) fibroblasts treated with plant extract (1201) from Solidago vigaurea subspecies alpestris 18.43
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 18.24
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 18.24
Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells 18.18
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 18.14
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 [RNA-seq] 18.14
Differential gene expression analysis between proliferating and quiescent human dermal fibroblasts 18.12
Gene expression analysis of human liver progenitor-like cells in culture 18.1
Single-cell RNA-seq reveals novel cell differentiation dynamics during human airway epithelium regeneration 17.96
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype 17.89
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype [RNA-Seq] 17.89
Gene Expression Analysis of Melanoma Cells Treated with 6-Thio-dG In Vitro 17.87
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 17.64
Toxoplasma gondii infection of human retinal pigment epithelial cells 17.63
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 17.5
Tumor exosome integrins determine organotropic metastasis 17.49
The Molecular Dissection of the Oncogenic Role of ETS1 in the Mesenchymal Subtypes of Head and Neck Squamous Cell Carcinoma [RNA-seq Cell lines] 17.42
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 17.41
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 17.41
Transcriptional impact of MTHFD2 in Human Aortic Endothelial Cells 17.38
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 17.33
Reprogrammed myeloid cell transcriptomes in NSCLC 17.23
Flura-seq identifies organ-specific adaptations in metastasis-initiating cells 17.16
Urinary sediment transcriptomic and longitudinal data to investigate renal function decline in type 1 diabetes 17.09
Distinct epigenomes in CD4+ T cells of newborns, middle-ages and centenarians. 17.01
Convergent roles of ATF3 and CSL in chromatin control of CAF activation [RNA-seq] 17.0
Convergent roles of ATF3 and CSL in chromatin control of CAF activation 17.0
Global transcriptional changes in U87MG glioblastoma cells upon shRNA-mediated TRIM52 knockdown 16.83
Transcriptomes of human monocytes after ex vivo exposure to uric acid 16.76
Identification of a Cell-of-Origin for Fibroblasts Comprising the Fibrotic Reticulum in Idiopathic Pulmonary Fibrosis 16.72
Transcriptional profiling of PBMC from patients with aGvHD and patients without aGvHD after alloHSCT 16.66
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 16.51
Analysis of the senescent transcriptome upon expression of a ZFP36L1 phosphomutant 16.13
Analysis of Combined Transcriptomes Identifies Gene Modules Differentially Responding to Pathogenic Stimulation in Vascular Smooth Muscle and Endothelial Cells 16.1
Cell-to-cell variation in defective virus expression and effect on host response during influenza virus infection 16.09
Identifying a novel candidate diagnostic and prognostic biomarker SPRR3 for oral squamous cell carcinoma via mRNA Sequencing and Bioinformatics 16.06
Transcriptome analysis of human airway epithelium infected by Human Bocavirus 1 16.04
Large-scale profiling of intracellular signalling pathway activation reveals major distinctions between airway smooth muscle cells of asthmatics and non-asthmatics. 15.87
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 15.78
STX4 Over-Expression in Human islets 15.72
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 15.7
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 15.7
Simultaneous quantification of antibody-RNA conjugates and the transcriptome from fixed cells by RAID 15.69
RNA deep sequencing analysis of human brain microvascular endothelial cells (ECs) treated with glioma-conditioned medium (glioma-CM) 15.65
CircRNAome diversity in human mature B-cells, T-cells and monocytes 15.59
Genome-wide expression analysis of young, senescent and p38MAPK-inhibitited senescent human fibroblasts. 15.55
RNA-Seq of polysome profiling fractions and whole cell lysates of UVB-irradiated N-TERT keratinocytes 15.49
Identification of a LIF-responsive replication-competent human β cell 15.34
polyA RNA Sequencing Analysis of HTR-8/SVneo cells after lnc-SLC4A1-1 overexpression 15.07
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 14.97
ChIP-seq and RNA-Seq analyses of epithelial and mesenchymal cells - HMLE, N8, N8-CTx 14.69
RNA-Seq comparisons of gene expression profiles of epithelial and mesenchymal cells - HMLE, N8, N8-CTx 14.69
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 14.69
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 14.52
SILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors 14.43
A transcriptome dataset revealing the molecular features of breast cancer stem cells 14.37
Genome-wide RNA-sequencing (RNA-seq) of benign and malignant prostate cell lines without and with androgen (R1881) stimulation. 14.28
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 14.05
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 14.05
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 14.02
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 14.02
Transcriptomic profiling of mesenchymal stem cells (MSC) differentiation into mesangial cells 13.84
Transcriptome analysis of human lung epithelial cells 13.78
Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4 13.78
A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (RNA-Seq) 13.73
Effects of rFVIIIFc on human macrophages 13.56
Reprogramming of dermal papilla cell intact gene signature with 3D culture and Lef-1 overexpression 13.5
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 13.47
Integrin signaling regulates YAP/TAZ to control skin homeostasis 13.44
Long non-coding RNA SMILR regulates genes involved in cytokinesis in human vascular smooth muscle cell 13.25
RNA-sequencing in immortalized human mammary epithelial cells 13.21
Alternative splicing regulated by QKI and RBFOX1 promotes the mesenchymal cell state in breast cancer 13.21
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 13.21
Androgen receptor programming in human tissue implicates HOXB13 in prostate pathogenesis 13.03
Androgen receptor programming in human tissue implicates HOXB13 in prostate pathogenesis [RNA-Seq] 13.03
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 13.01
Treatment of prostate cancer cells with S-adenosylmethionine leads to genomewide alterations of transcription profiles 12.84
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 12.61
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 12.5
HBEC-shp53-PCHD7 12.47
mRNA sequencing of the mouse and human Hep-Orgs, Chol-Orgs and primary hepatocytes 12.43
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner 12.02
Epigenome regulation during epidermal lineage commitment [RNA-seq] 12.0
Human Bone Marrow Assessment by Single Cell RNA Sequencing, Mass Cytometry and Flow Cytometry [bulk] 11.97
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 11.92
Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans. 11.76
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NfkB-dependent differentiation of AML cells 11.74
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 11.41
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of AIM2. 11.39
Genes altered in expression by Cisplatin treatment in lung cancer cell lines 11.13
circRNA-sequencing 11.0
Gene expression profile of human placenta from T. Cruzi infected mothers 10.95
mRNA differential expression analysis in a human ex vivo model of chronic wounds 10.82
Early response of human ovarian and fallopian tube surface epithelial cells to norepinephrine 10.61
The contribution of adenosine receptor 3-mediated signaling to TLR4-induced responses by human dendritic cells 10.36
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 10.21
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 10.21
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 10.17
Genome-wide maps of transcriptomic and epigenomic state in melanoma cell lines 9.95
Bulk RNA-sequencing of cell types isolated by FACS from normal human prostates 9.95
Transcriptome landscape of human primary monocytes response upon different ligand glucocorticoids 9.92
TSLP acts on neutrophils to drive complement-mediated killing of methicillin-resistant Staphylococcus aureus 9.9
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk 9.71
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk [RNA-seq] 9.71
Absence of NKG2D ligands defines human leukaemia stem cells and mediates their immune evasion 9.57
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells 9.55
Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia 9.46
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer 9.45
Characterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer 9.42
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 9.38
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 9.29
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) in proliferation, quiescence, senescence and transformed states. 9.28
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 9.27
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 9.25
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 9.25
Next-generation RNA sequencing to determine changes in gene expression during breast cancer progression 9.21
Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer 9.18
RNA-seq analysis upon ARID1B overexpression 9.17
De novo reconstruction of human adipose reveals conserved lncRNAs as regulators of brown adipogenesis 9.16
Effects of transcription on genome - nuclear lamina interactions: RNA-seq data 8.89
Effects of transcription on genome - nuclear lamina interactions 8.89
RNA-seq and flow-cytometry of conventional, scalp, and palmoplantar psoriasis reveal shared and distinct molecular pathways 8.78
RNA-seq identifies novel lncRNAs involved in vascular smooth muscle cell proliferation 8.69
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 8.69
Identification of the networks that regulate human monocytic myeloid-derived suppressor cell differentiation into inflammatory macrophages 8.39
Epigenome regulation during epidermal lineage commitment 8.32
Gene expression profile in endometrial organoids cultured in normal follicular phase vs PCOS-like hormone profile 8.32
TGF-β regulation of miRNA expression in pancreatic cancer 8.29
SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors 8.24
RNA-seq of human foreskin fibroblast cells lacking RB and/or p130 after doxorubicin treatment 8.15
Transcriptional analysis of ZIKV-infected Ifnar-/- and Ifnar+/- placentas and IFN-beta (IFN-b) or IFN-lambda (IFN-l) treated human mid-gestation chorionic villus explants 8.11
Analysis of transcriptional differences after IFN-beta (IFN-b) or IFN-lambda (IFN-l) treated human mid-gestation chorionic villus explants 8.11
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 8.04
Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity 8.01
RNA sequencing of human mammary epithelial cells 7.92
CRIG identifies a novel population of highly phagocytic peritoneal macrophages associated with disease severity in patients with cirrhosis and ascites 7.81
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer 7.7
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways [RNA-seq] 7.57
Altered Hydroxymethylation is seen at regulatory regions in pancreatic cancer and regulates oncogenic pathways 7.57
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes (RNA-Seq) 7.43
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes 7.43
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program (RNA-Seq) 7.4
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program 7.4
CRISPR-Cas9 based screen for p53-bound enhancers that function in oncogene-induced senescence 7.34
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  7.32
Investigation about fibroblasts of different origins in culture 7.22
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 7.19
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 7.1
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 7.09
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration 7.04
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 6.93
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 6.84
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 6.84
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 6.81
JAG1 Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium 6.59
Dexamethasone inhibits respiratory syncytial virus-driven mucus production while increasing viral replication without altering antiviral interferon signaling 6.56
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 6.45
Gene expression profiles of BxPC-3, MiaPaCa-2 and PANC-1 cell lines treated with DMSO and THZ1 respectively 6.39
Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii 6.11
The influence of PPFIA1 silencing to gene expression in breast carcinoma cell line and head and neck squamous cell carcinoma cell lines by RNA-sequencing in three dimensional collagen I 6.1
RNA expression profiles from HUVECs overexpressing adenovirally delivered HIF1a and HIF2a proteins 6.09
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 6.07
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 5.95
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 5.91
Long non-coding RNA expression profile associated with malignant progression of oral submucous fibrosis 5.87
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 5.87
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells (2) 5.81
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells 5.81
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 5.76
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 5.7
Subcellular pathways shared by afflicted patients and mutant mice identify a new drug treatment for aortic aneurysm in Marfan syndrome 5.64
Novel SF3B1 Deletion Mutations Result in Aberrant RNA Splicing in CLL Patients 5.57
Splicing and gene expression changes in human mammary epithelial MCF-10A cells expressing SR or SR-like proteins 5.53
Next Generation Sequencing of Lung Primary Fibroblast Responding to Eosinophil-Degranulation Products 5.48
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules [gene expression] 5.45
Conversion of Human Gastric Epithelial Cells to Multipotent Endodermal Progenitors using Defined Small Molecules 5.45
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription [RNA-Seq] 5.38
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription 5.38
The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing [RNA-seq] 5.35
Transcriptome Analysis and Functional Identification of Adipose-Derived Mesenchymal Stem Cells in Secondary Lymphedema 5.27
MicroRNA targetome analysis during HCMV infection 5.23
Effect of from Human Umbilical Vein Endothelial Cells 5.18
Expression of the mannose receptor (CD206) defines distinct populations of human colonic macrophages in health and inflammatory bowel disease 5.12
Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome 5.01
Hypoxic regulation of gene expression in HUVEC is dominated by EPAS1 4.94
Transcriptome analyses of human pancreatic islets and pseudoislets 4.94
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 4.93
Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance  4.87
Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders 4.85
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 4.68
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 4.68
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 4.68
Ribosome profiling and RNA sequencing of MCF10A-ER-Src and fibroblast cell transformation 4.66
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis 4.49
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis: Expression data (RNA-seq) 4.49
Analysis of transcriptional regulation by Myt1 and Myt1l 4.25
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 4.22
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 4.22
CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Humans 4.2
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 4.2
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 4.2
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 3.95
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 3.89
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 3.89
Redifferentiation of expanded human islet β cells by inhibition of ARX 3.76
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 3.74
Effect of hyperfractionated irradiation (HFRT) of prostate primary basal cells (PrEPs) on the transcriptome 3.71
RNA-seq of IL-4 stimulated human keratinocytes 3.69
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 3.51
MAIT cell RNA sequencing 3.41
Role of cervicovaginal microbiota in genital inflammation 3.4
Transcriptome of Primitive Human Hematopoietic Cells: A New Resource to Find hHSC-Specific Genes 3.4
PANCR, the PITX2 adjacent noncoding RNA, is specifically expressed in human left atria and regulates PITX2c expression 3.39
RNA sequencing of GLO1-depleted MDA-MB-231 breast cancer cells 3.31
Transcriptional Profiling of Werner Syndrome (WS) iPSC-derived MSC and the isogenic gene-edited controls 3.31
RNA-Seq of Breast and Ovarian Cancer Cell Lines 3.26
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 3.09
Aneuploidy-induced cellular stresses limit autophagic degradation. 3.07
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 3.06
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 2.87
Transcriptional changes during naturally-acquired ZIKA Virus infection render dendritic cells highly conducive to viral replication 2.74
High throughput analysis of three human adipose cell lines PAZ6, SGBS and SW872 2.68
RNA-seq data 2.68
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 2.66
Tpl-2 and MEK small molecule inhibitors 2.59
Tpl-2 small molecule project 2.59
The role of CFTR in islet function 2.58
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB 2.54
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 2.5
RNA-seq study reveals unique transcriptome expression in systemic lupus erythematosus patients with distinct autoantibody profile 2.46
Human islets of varying quality: the good, the (not so) bad and the ugly 2.39
Transcriptome of EBV-infected gastric cancer cell lines 2.31
Expression profiling of pancreatic adenocarcinoma and ductal adenocarcinoma cell lines. 2.28
A monocyte gene expression signature in the early clinical course of Parkinson’s disease 2.25
Transcriptome profiling of CXCR2+ neuroendocrine (NE) tumor cells purified from patients' fresh prostate adenocarcinoma 2.08
RNA-sequencing of highly pure synovial tissue macrophages reveals two distinct osteoarthritis subgroups that indicate different disease mechanisms. 2.08
Histone Demethylases KDM3A and KDM4C regulate mesenchymal stromal cell senescence and bone aging through condensin-mediated heterochromatin organization 2.0
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray 2.0
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray [RNA-Seq] 2.0
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates 1.92
Reprogramming of Tumor-infiltrating Immune Cells in Early Stage of NSCLC 1.87
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 1.86
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 1.85
Specific molecular signatures underlie response to decitabine in CMML 1.79
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 1.79
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 1.76
Single cell transcriptome of peritoneal cells 1.76
Chemical Enhancement of Direct Cardiac Reprogramming In Vitro and In Vivo 1.76
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 1.71
CHD1 regulates cell fate determination by activation of differentiation-induced genes 1.6
The transcriptome of human endometrial mesenchymal stem cells under TGFβR inhibition reveals improved potential for cell-based therapies 1.56
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 1.51
The Genomic Landscape of Atypical Fibroxanthoma 1.43
Transcriptomic analysis of human macrophages in 3D 1.21
mRNA sequencing of oropharyngeal cancer cell lines 1.18
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease (human) 0.95
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease 0.95
The secretome of skin cancer cells activates the mTOR/MYC pathway in healthy keratinocytes and converts them into tumorigenic cells 0.94
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 0.89
RNA-Seq of human PDA cell lines transfected with control siRNA or Pdx1 siRNA 0.69
Small extracellular vesicles are key regulators of non-cell autonomous intercellular communication in senescence via the interferon protein, IFITM3 0.6
Apoptosis enhancing drugs overcome innate platinum resistance in CA125 negative tumor initiating populations of high grade serous ovarian cancer 0.56
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 0.49
6mer seed toxicity in viral microRNAs 0.38
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 0.35
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 0.35
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 0.3
Effect of SHP2 inhibition on hepatic stellate cell transcriptome. 0.21
CSL RNA-Seq on HKC and SCC cell lines 0.19
CSL 0.19
Differences in miRNA Detection Levels are Technology and Sequence Dependent 0.17
Differences in miRNA Detection Levels are Technology and Sequence Dependent [NGS] 0.17
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 0.15
Antibiotics induce polarization of pleural macrophages to M2-like phenotype in patients with tuberculous pleuritis 0.14
Cutaneous Immunoprofile of Three Spotted Fever Group Rickettsiosis 0.01


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