Gene Query: SFRP1

Dataset Description Geneva Score
circRNA-sequencing 191.48
The effect of spontaneous acquisition of an extra chromosome 7 for engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 177.7
IRF2 is a master regulator of human keratinocyte stem cell fate [RNA-seq] 157.14
IRF2 is a master regulator of human keratinocyte stem cell fate 157.14
Global Gene Expression Changes in Cholangiocytes Treated with TGF-beta 132.73
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 111.65
Human embryonic stem cells in E8 and AKIT culture medium 111.65
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq Human] 111.58
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 105.43
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 105.14
mTOR hyperactivation in Down Syndrome mediates deficits in autophagy induction, autophagosome formation, and mitophagy 99.32
Gene expression profile using RNA-seq in WC00060 or SR-0788 cells transfected with siRNA for KPC1 or control 94.99
Transcriptome of human keratinocytes with or without HPV16 oncogene expression 88.59
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B 86.22
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 84.68
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 83.86
Gene expression profile of human iPSC-derived nephron progenitor cells 81.23
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation 81.15
Bladder cancer associated mutations in RXRA activate peroxisome proliferator-activated receptors 81.15
Transcriptomic Profiling of Developing Human Paraxial Mesoderm from 4.5-5 Weeks of Gestation Human Embryos 78.94
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 77.66
Codon usage optimization in pluripotent embryonic stem cells [tRNA sequencing] 77.3
Nonpregnant and term pregnant human myometrial tissues 77.04
Transcriptomic profiles of nonpregnant and term pregnant human myometrial tissues 77.04
PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome 74.65
PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome [RNA-seq] 74.65
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons [RNA-seq] 74.16
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons 74.16
G-quadruplex structures mark human regulatory chromatin 74.08
RNA-seq of human fibroblasts after irradiation 73.82
Analysis of Combined Transcriptomes Identifies Gene Modules Differentially Responding to Pathogenic Stimulation in Vascular Smooth Muscle and Endothelial Cells 72.42
Transcripotome analysis of different locations of hair follicles (bulb, bulge) in androgenetic alopecia 71.59
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 70.75
RNA-seq of human aneuploid cell lines with Trisomy 21 70.1
Comprehensive RNA sequencing of healthy human endometrium at two time points of the menstrual cycle 68.85
RNA-Seq analysis of primary human keratinocytes exposed to Cannabidiol 68.15
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth 67.42
mRNA Profiling of miR-17 family inhibition using TuD lentiviral vector in HepG2 and SK-Hep1 hepatocellular carcinoma cell lines [RNA-Seq] 67.42
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 66.2
RNA sequencing analysis of human embryonic stem cells and axial progenitors 66.13
The effect of PPARG inhibition on human angiomyolipoma cells 64.82
Virus Mimicry in the Tumor Microenvironment Activates RIG-I Through Unshielding of Endogenous RNA in Exosomes [RNA-Seq] 63.68
Transcriptome profiling of microRNA-mediated neuronal reprogramming with REST repression at day 7 62.91
Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration 61.81
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 61.59
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 59.56
Bone marrow-derived and dental pulp-derived human mesenchymal stem cell RNA-Seq 59.4
Improved LCL to iPSC reprogramming: RNA Analysis of LCLs, reprogrammed iPSCs, and differentiated NSCs reveal potential regulatory and functional processes involved in these cellular transitions. 59.05
RNA-seq Transcriptome Analysis of AD169 and AD169-ΔUL26 infected MRC5 fibroblasts. 58.02
Targeting EZH2 in MYCN-amplified Neuroblastoma [RNA-seq] 57.28
Targeting EZH2 in MYCN-amplified Neuroblastoma 57.28
RNA-seq and Microarray in Transcriptome Profiling of Anterior Cruciate Ligament Tears: Implications for Prognostic Biomarkers Discovery 56.73
RNA-seq from control and macroH2A1-depleted IMR90 primary human lung fibroblasts 56.65
Exploring the role of macroH2A1 in transcription regulation in IMR90 primary human lung fibroblasts with RNA-seq and ChIP-seq 56.65
6mer seed toxicity in tumour suppressive microRNAs 56.56
RNA-seq data for non-targeting siRNA and CDK11 siRNA transfection in SHhES8 cells 56.27
PTP4A1 phosphatase is overexpressed in systemic sclerosis fibroblasts and promotes TGFb signaling 55.01
Maturing an Enteric Nervous System in Human Intestinal Organoid-derived Tissue-Engineered Small Intestine 54.95
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer 54.67
Cancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor development 54.57
Gene expression analysis of a panel of human fibroblasts that generate an aligned (anisotropic) vs non-aligned extracellular matrix 54.18
RNA-seq of SOX5 overexpressing primary human neuronal progenitors 53.78
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer [RNA-Seq] 53.35
Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs 51.04
Alu RNA modulates the expression of cell cycle genes in human fibroblasts 49.64
Global analyses of the effect of different cellular contexts on microRNA targeting (RNA-Seq) 49.59
Global analyses of the effect of different cellular contexts on microRNA targeting 49.59
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 49.51
RNA helicase A is necessary for KIF1Bβ tumor suppression in neuroblastoma 48.96
CDK12 inhibition in Hep3B, Huh7 and SNU449 cells 48.38
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 48.26
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 48.26
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 48.21
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 48.21
RNA sequencing to compare gene expession in control and PF228-treated hepatic stellate cells 48.06
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma [RNA-Seq; normal samples] 47.75
Human RELA haploinsufficiency results in autosomal dominant chronic mucocutaneous ulceration: the transcriptional profile of RelA haploinsufficient patients 47.38
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 47.22
hTERT promotes cell adhesion and migration independent of telomerase activity 47.2
Fbxo32 mediated gene expression program underlies EMT and metastasis 46.95
Regionally distinct astrocyte interferon signaling promotes blood-brain barrier integrity and limits immunopathology during neurotropic viral infection 46.73
Expression alterations induced by restoration of AXIN1 expression in SNU449 hepatocellular carcinoma cells 46.42
A prostate cancer chromatin interaction map 45.61
RNA expression following TMPRSS11B overexpression or depletion 45.52
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 44.84
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 44.36
ZNF131 suppresses centrosome fragmentation in Glioblastoma stem-like cells through regulation of HAUS5 44.08
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 43.76
Genes regulated by SPDEF or FOXA3 in A549 lung carcinoma cells [RNA-seq] 43.39
Gene expression analysis in U251 and U87 cells transduced with NANEP5 vector. 42.86
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 42.83
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 42.51
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 41.5
Human Long Intergenic Noncoding RNA Linc-ADAL Knockdown in Mature Adipocytes using Lentiviral ShRNA 41.36
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 41.33
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 41.18
Mammalian Hbs1L deficiency causes Pelota depletion and is associated with a unique phenotype 41.15
Next Generation Sequencing Facilitates Quantitative Analysis of ALDH+ E-BCSC, CD24-CD44+ M-BCSC and Bulk tumor cell Transcriptomes from MC1 and Vari068 PDX models of TNBC 40.79
Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols 40.06
Lineage specific differentiation is influenced by state of human pluripotency 40.02
Lineage specific differentiation is influenced by state of human pluripotency [RNA-seq] 40.02
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 39.92
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 39.55
Genome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells 39.42
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 39.38
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected EVT cells 39.29
Endometrial transcriptome and PGR cistrome in cycling fertile women [RNA-seq] 38.64
Endometrial transcriptome and PGR cistrome in cycling fertile women 38.64
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 38.57
Next Generation Sequencing of isolated EGFR+ and HLA-G+ first trimester human trophoblasts 38.57
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 38.33
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 38.31
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 37.07
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 36.24
Differentially expressed vascular development genes for iPSC-ECs from CDI 35.27
Effect of Hypoxia in Severe Preeclampsia through Epigenetic Regulation 35.23
Transcriptomics profiles of patient-matched normal kidney and ccRCC pairs 35.21
p63 establishes epithelial enhancers de novo at critical craniofacial development genes 35.09
Expression profiling of converted and control dermal BJ fibroblasts 35.09
Maturation of human iNSCs 34.51
Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors 34.25
MCF10A H-Ras RNA-Seq 34.18
The Cushing's disease adipose gene expression profile reveals effects of long term glucocorticoids on adipose tissue lipid, protein and glucose metabolism 34.09
ChIP-seq and RNA-Seq analyses of epithelial and mesenchymal cells - HMLE, N8, N8-CTx 34.02
RNA-Seq comparisons of gene expression profiles of epithelial and mesenchymal cells - HMLE, N8, N8-CTx 34.02
Poly(ADP-ribosyl)ation dependent changes in CTCF-chromatin binding and gene expression in breast cells 33.85
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 33.69
Genome-wide identification of cancer-specific alternative splicing in circRNA 33.56
Generation of trichogenic adipose-derived stem cells by expression of three factors 33.31
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 33.3
JunB control of keratinocyte-mediated inflammation [RNA-seq] 33.28
RNA-Seq and ChIP-Seq reveals SQSTM1/p62 as a key mediator of JunB suppression of NF-kB-dependent inflammation 33.28
Gene expression changes in human melanoma cell lines compared to primary melanocytes 32.69
Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells 32.53
Integration of genome-wide DNA methylome and transcriptome of human intestinal fibroblasts reveals novel candidate gene signatures in Crohn’s disease-associated fibrosis 32.29
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 31.92
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity 31.83
Transcriptional changes after overexpression of proliferation drivers in human mammary epithelial cells. 31.67
Identification of the role of polydom in neurofibromas 31.61
Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells 31.41
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination (RNAseq) 31.29
Response of triple negative breast cancer to BAZ2A/B inhibition and BET bromodomain inhibition alone and in combination 31.29
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 31.25
Transcriptomic and gene ontology profiling of the human corneal cell types 31.16
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 31.02
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells 30.84
Transcriptome sequencing of differentially expressed genes in acne inversa (AI) patients with NCSTN mutation and healthy individuals 30.81
Transcriptome sequencing of differentially expressed genes in mouse and human skin with and without NCSTN mutation 30.81
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 30.74
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 30.74
RNA-seq during MCF10A-ER-Src cell transformation and upon factor knockdowns 30.48
Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation 30.48
Zika infected neural stem cells 30.44
Transcriptome analysis of Zika infected neural stem cells 30.44
Transcription elongation factors are in vivo-specific cancer dependencies in glioma 30.43
RNA-seq Profiles in Transcription elongation factors are in vivo-specific cancer dependencies in glioma 30.43
Expression level comparison under dividing and quiescent states in human primary fibroblasts 30.35
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 30.11
HBEC-shp53-PCHD7 29.93
Effect of hypoxia and TGFβ1 on gene expression in HPF fibroblast cells 29.84
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 29.77
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 29.76
Examining serotonergic neuron differentiation from human iPSCs 29.7
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 29.66
TFAP2C signalling in human fibroblasts 29.66
Convergent roles of ATF3 and CSL in chromatin control of CAF activation [RNA-seq] 29.53
Convergent roles of ATF3 and CSL in chromatin control of CAF activation 29.53
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 29.43
Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells 29.08
RNA-sequencing of pediatric idiopathic dilated cardiomyopathy patients and healthy controls 28.89
RNA-seq analysis of HT-29, MCF10A, and MDA-MB-436 cells 28.65
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 28.46
Nucleoporin-mediated regulation of cell identity genes 28.31
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [d7+d14] 28.25
AKAP8 inhibits tumor metastasis by antagonizing EMT-associated RNA alternative splicing 27.98
NEUROD1 dependent gene regulation in murine pancreatic endocrine cells and human stem cell derived insulin producing cells 27.88
Rna-seq transcriptome data for insulin-GFP+ cells differentiated from NEUROD1 knock out and NEUROD1+/+ control human embryonic stem cells. 27.88
Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines 27.86
RNA-Seq profiling of day 7 and day 18 kidney organoids differentiated in two batches 27.7
Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium 27.64
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 27.64
RNA seq_A375 gSMARCB1 + A549 etoposide, Aurora kinases inhibitors treated 27.59
hiPSCs unravel aberrant TGFβ signaling as an etiology of left ventricular non-compaction 27.45
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 27.38
Functional astrocytes differentiated from hiPSCs 27.37
RNAseq of IL-36 stimulated primary human keratinocytes 27.3
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics 27.29
Generation of a Panel of Induced Pluripotent Stem Cells From Chimpanzees: a Resource for Comparative Functional Genomics (RNA-Seq) 27.29
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 26.92
Regulation of Lipids is Central to Replicative Senescence 26.73
m6A level and isoform characterization sequencing (m6A-LAIC-seq) reveal the census and complexity of the m6A epitranscriptome 26.57
Modeling the MYC-driven normal-to-tumour switch in breast cancer. 26.49
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription 26.39
Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription [RNA-Seq] 26.39
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 26.35
PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA 26.31
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies 26.19
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis 26.09
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis: Expression data (RNA-seq) 26.09
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 26.09
Identification of Resistance Genes to BRAF Inhibitor in Melanoma by piggyBac Transposon Activation Mutagenesis Screen 25.97
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 25.82
Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders 25.81
Differential gene expression in Jagged1 treated human dental pulp cells. 25.81
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 25.54
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 25.46
RNA-Seq of Kaposi’s sarcoma reveal alterations in glucose and lipid metabolism 25.41
Whole transcriptome RNA sequencing of human cells after HCV infection (ML-1 thyroid cell line, primary thyrocytes and Huh7.5 hepatocyte cell line) 25.08
In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells 25.06
Wnt5a and its downstream transcription factor Stat3 are therapeutic targets for diffuse intrinsic pontine gliomas 24.97
Evolved Labels of Placental Invasion in Human and Bovine Endometrial Stroma 24.96
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells 24.86
Generation of KRAS signatures using immortalized isogenic lung cells. 24.61
A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis 24.6
ELP1 splicing correction reverses proprioceptive sensory loss in familial dysautonomia 24.59
Differential gene expression of static and intermittent compressive force treated human periodontal ligament cells 23.96
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 23.95
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 23.89
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes [RNA-seq] 23.81
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes 23.81
Characterization and therapeautic application of mesenchymal stem cells with neuromesodermal origin from human pluripotent stem cells 23.79
microRNA-seq and RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 23.78
RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 23.78
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 23.72
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. [RNA-seq] 23.56
Molecular Signature of CAID Syndrome: Noncanonical Roles of SGO1 in Regulation of TGF-β Signaling and Epigenomics. 23.56
Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma 23.44
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 23.31
Oncogenic changes and EMT in normal human bile duct epithelial cells are caused by parasite-derived materials and N-nitrosodimethylamine 23.28
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 23.23
A common cell state in Triple Negative Breast Cancers represents a druggable vulnerability 23.22
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB 23.03
Proteomics identifies a marker signature of MAPKi resistance in melanoma 22.97
Epigenomic landscape during organ formation in human early embryos 22.91
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 22.88
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 22.87
High-depth RNA sequencing of isogenic wild-type, PIK3CA-WT/H1047R and PIK3CA-H1047R/H1047R human iPSCs 22.69
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 22.65
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 22.6
Ribosome profiling of TGFb-treated cells indicates reduced leucine availability 22.49
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation, modulates translation and spliceosomal processes 22.47
High level DNA repair gene expression in human ES cells 22.38
Transcriptome profiling of a mouse model of alveolar soft part sarcoma 22.27
Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues 22.26
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 22.25
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 22.25
Transcriptional responses of melanoma cells to BRAF inhibition 22.18
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 22.13
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 22.04
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 22.03
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas 21.93
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 21.91
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 21.79
Single Cell Analysis Reveals Unexpected Transcriptional Heterogeneity of Neural Progenitors in the Developing Human Cortex 21.75
Proliferation pause as an early blockade of human cellular reprogramming toward pluripotency [RNA-seq analysis] 21.71
LncPRESS1 is a p53-regulated lncRNA that safeguards pluripotency by disrupting SIRT6 mediated de-acetylation of histone H3K56 21.38
mRNA-Seq profiling of human developing kidney 21.36
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 21.34
Next Generation Sequencing Analysis of human embryonic stem cells derived MESP1-mTomato reporter cells 21.32
Effect of disulfiram treatment on pediatric high grade glioma 21.13
Small-molecule targeting of brachyury transcription factor addiction in chordoma 21.13
Differential expression of genes in AD169-infected MRC5. 20.73
HLA peptides derived from tumor antigens induced by inhibition of DNA methylation for development of drug-facilitated immunotherapy 20.54
Codon usage optimization in pluripotent embryonic stem cells [RNA-seq] 20.36
A myogenic double reporter human pluripotent stem cell line allows prospective isolation of skeletal muscle progenitors 20.16
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy [RNA-Seq] 20.06
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy 20.06
Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells 20.05
Differentially expressed (DE) genes analysis in synovial fluid mesenchymal stem cells (SF-MSCs), SF-MSC derived iPSCs and iPSC derived MSCs (iPSC-MSCs) 19.88
RNA-seq analysis and shRNA screen of breast cancer 19.78
RNA-seq analysis of breast cancer 19.78
CSL 19.76
CSL RNA-Seq on HKC and SCC cell lines 19.76
Modeling and characterization of the dynamic gene regulatory networks underlying cancer drug resistance based on time-course RNA-seq data 19.69
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes 19.69
Transcriptomic profiling of human coronary artery endothelial cells under laminar shear stress (LS), oscillatory shear stress (OS) and static culture (ST) 19.66
Dissecting the dynamics of signaling events in the BMP,WNT and NODAL cascade during self-organized fate patterning in human gastruloids 19.65
Expression profiling of lncRNAs, miRNAs and mRNAs and their differential expression in leiomyoma using next generation RNA sequencing 19.54
RNA-seq in HepG2 and IMR90 cells 19.53
Evolution of a transcriptional regulator from a transmembrane nucleoporin 19.53
The Role of Histone H3 Lysine 36 Methylation in Reprogramming of fibroblasts and on Induced Pluripotent stem Cell Generation 19.45
Morphological and molecular characterization of human dermal lymphatic collectors 19.45
Toxoplasma gondii remodels the cis-regulatory landscape of infected human host cells 19.18
Toxoplasma gondii remodels the cis-regulatory landscape of infected human host cells [RNA-seq] 19.18
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier 19.18
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier [human] 19.18
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 18.98
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 18.98
RNA Seq analysis of NKX2-5 Null and Het human embryonic stem cells in cardiomyogenesis 18.98
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells [RNA-seq] 18.89
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells 18.89
Metabolism as an early predictor of DPSCs aging 18.83
Integrated Profiling of mRNAs and microRNAs to Identify Potential Biomarkers for Oral Malignant Transformation [mRNA-Seq] 18.77
Integrated Profiling of mRNAs and microRNAs to Identify Potential Biomarkers for Oral Malignant Transformation 18.77
Transcriptomic Dynamics during Differentiation Process of Human Pluripotent Cells into Hepatocyte-like Cells 18.72
Splicing and epigenetic factors jointly regulate epidermal differentiation 18.64
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 18.57
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 18.55
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 18.55
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 18.4
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes (RNA-seq) 18.39
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes 18.39
iPSC derived motor neuron cultures from C9ORF72 carriers 18.33
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 18.29
Gene Expression Analysis of Melanoma Cells Treated with 6-Thio-dG In Vitro 18.23
The interplay between SOX4 and SMAD3 in the context of breast cancer 18.06
DIGIT regulates endoderm differentiation of human embryonic stem cells 17.85
DNA Methylation Reprograms Metabolic Gene Expression in End-Stage Human Heart Failure 17.5
A Novel Population of Human Cardiac Resident Mesenchymal Stem Cells 17.49
Osteogenic programming of adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the Polycomb protein EZH2 17.43
Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors 17.12
OBESITY IS ASSOCIATED WITH IMPAIRED EXPRESSION OF THE GLYCOSYLTRANSFERASE EOGT IN DECIDUALIZING ENDOMETRIUM 17.06
RNA-sequencing based transcriptome-wide expression profiling of Cynomolgus monkey and human IPSCs in vitro differentiated into endothelial cells 16.93
Genome-wide Analysis of Chromatin Interactions in Human Cells 16.78
PANC-1 and AsPC-1 human pancreatic carcinoma cells under hypoxia, nutrient starvation and low pH culture condition 16.7
Transcriptome profiling of self-renewing hESCs and multipotent mesoderm progenitor cells as a function of substrate stiffness 16.43
Hypoxic transcriptome of SQ20B human head and neck cancer cells 16.4
High-throughput RNA sequencing on circular RNA profiles of human triple-negative breast cancer and adjacent normal tissues 16.25
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 16.16
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 16.09
Chronophin regulates metabolic and transcriptomic features of glioblastoma stem-like cells 16.05
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells 15.89
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia [shRNA] 15.87
Reconstitution of the human pancreatic niche stimulates differentiation of hESCs into beta cells and reveals new signals for pancreatic endocrine cell maturation 15.62
Total RNA sequencing of prospective axial stem cell cultures derived from human pluripotant stem cells 15.61
CDK12 regulates alternative last exon mRNA splicing and promotes invasion of a breast cancer cell line 15.34
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 15.26
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 15.24
Robust generation of honemogeneous midbrain organoids with in vivo–like cellular composition facilitates neurotoxin-based Parkinson’s disease modeling 15.13
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 14.73
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 14.68
AMPK signaling for naïve pluripotency 14.65
AMPK signaling for naïve pluripotency [Hs] 14.65
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 14.28
Genome-wide profiling of cervical RNA-binding proteins identified HPV regulation of RNASEH2A expression by viral E7 and E2F1 14.17
Transcriptome sequencing analysis of BRAF-mutant melanoma metastases. 14.14
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 14.14
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency [RNA-Seq] 13.97
Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency 13.97
Identification of Sin3B regulated genes during quiescence 13.74
RNA sequencing Facilitates Quantitative Analysis of luminal breast cancer cells and basal breast cancer cells Transcriptomes 13.72
A practical evaluation of alignment algorithms for RNA variant calling analysis 13.48
Expression data from human perivascular stem cell-derived extracellular vesicles (PSC-EVs) and PSCs 13.01
Non-transmissible measles virus vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells 12.99
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) 12.86
Gene expression of thyroid cancer cell lines 12.75
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease 12.59
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease (human) 12.59
RNA-seq of cancer cell lines treated with T-025 12.47
mRNA expression data from human parthenogenetic haploid ESCs (hPGES), normal ESCs (H9) and human fibroblast 12.43
Genomic analysis of human parthenogenetic haploid ESCs (hPGES), normal human ESCs(H9) and human forskin fibroblast 12.43
Transcriptome of melanoma cell lines resistant to inhibition of the MAPK pathway. 12.31
Analysis of MGE Transcriptomes with or without Ctnnb1 knockout in human through RNA Sequencing 11.64
Disruption of GRIN2B impairs differentiation in human neurons 11.6
RNA-seq analysis of the human fetal kidney. 11.57
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 11.22
RNA binding protein CPEB1 remodels host and viral RNA landscapes [RNA-Seq] 11.22
Next Generation Sequencing Facilitates Quantitative Analysis of mesoderm posterior bHLH transcription factor 1(MESP1)+ and MESP1- cells' Transcriptomes 11.07
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 11.05
Transcriptomic analyssis following EHMT1/2 inhibition 10.98
Ex vivo expanded human 3D Nephrospheres engraft long term and repair chronic renal injury in mice 10.81
A comparison of gene expression between lesional and non-lesional derived keratinocytes of Hailey-Hailey disease patients. 10.34
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 10.31
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 10.31
Transcriptomics analysis of gene expression in multiple human and mouse cells and tissues 10.29
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes 10.29
ChIP-seq and RNA-seq analysis of KMT2D-silenced metastatic melanoma cells 10.28
RNA-Seq of the corpus callosum from 12 individuals 10.15
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 9.99
Dilated cardiomyopathy vs Myocarditis 9.73
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 9.72
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 9.72
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion 9.62
Characterization of the Merkel cell carcinoma miRNome 9.6
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 9.41
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 9.41
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 9.23
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 9.21
cKIT+ sorted cells from 57-137 day old fetal testes and ovaries 9.2
RNA-Seq of cKIT+ sorted cells from 53-137 day old fetal testes and ovaries and RNA-Seq of TRA-1-81+ H1 and UCLA1 hESCs. 9.2
Genome-wide maps of transcriptomic and epigenomic state in melanoma cell lines 9.16
Identification of miRNA signatures during the differentiation of hESCs into retinal pigment epithelial cells 9.08
Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner 9.05
ARID1A and ARID1B loss in HCT116 and TOV21G cells 8.95
High throughput analysis of three human adipose cell lines PAZ6, SGBS and SW872 8.91
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 8.84
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 8.84
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 8.75
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 8.74
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 8.48
CD13 and ROR2 permit isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 8.47
Isolation of highly enriched cardiac mesoderm from differentiating human embryonic stem cells 8.47
RNA-seq of stable and unstable section of human atherosclerotic plaques 8.47
Activity-dependent transcriptional changes in human neurons 8.29
Hyper-activation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2 8.12
RNA splicing alteration on glioblastoma and normal neural stem cells 7.77
Transcriptome profiling of de-differentiated chondrocytes over-expressing miR-138 or miR-181ab1 during osteogenic induction 7.71
Gene expression profile of CRC-derived HILEC 7.68
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 1) 7.66
Neurofibroma 7.64
Differential expression in wild-type and mutant neurofibroma and MPNST cell lines 7.64
FGF2 regulation of gene expression in stable inducible Neurons 7.57
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription 7.56
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription.[RNA-seq and ChIP-seq] 7.56
Expression profile of GIST48 cells with siETV1 or siFOXF1 knockdown 7.49
FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST) 7.49
MUC1-C Drives Lineage Plasticity in Progression to Neuroendocrine Prostate Cancer 7.46
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 7.44
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 7.44
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 7.17
Generating Patterned Kidney Organoids for Studying Development and Diseases [bulk RNA-Seq] 7.06
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming 6.9
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming (RNA-seq fibroblasts) 6.9
Effect of OVO-like 1 knockdown on global transcript expression in differentiated BeWo trophoblast cells 6.83
Next Generation Sequencing Compares Effects of microRNA-9 perturbation in control and SZ hiPSC NPCs 6.69
Steroid Receptor Coactivator-2 Regulated Transcriptome in Human Endometrial Stromal Cells 6.67
Pericyte-like cells generated from human pluripotent stem cells support hematopoietic stem and progenitors ex vivo 6.66
Low MITF/AXL ratio predicts early resistance to multiple targeted drugs in melanoma 6.59
CHCHD2 gene KO effect in iPSC drived motor neurons 6.5
ERBB3 and NGFR mark distinct skeletal muscle progenitor cells in human development enabling enrichment and maturation of hPSC muscle 6.42
Histone H3.1K27 methylation promotes NHEJ by antagonizing FANCD2 on Chromatin 5.93
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 5.73
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 5.73
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 5.72
mRNA-sequencing of breast cancer subtypes and normal tissue 5.65
Extracellular matrix (ECM) stiffness and collagen-1 (col-1) responsive genes in 3D cultured mammary epithelial cells 5.45
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype [RNA-seq] 5.4
Cancer Associated Fibroblasts are defined by a core set of epigenome changes that contribute to the tumor phenotype 5.4
Zika virus infection reprograms global transcription of host cells to allow sustained infection 5.32
RNA-Seq of Breast and Ovarian Cancer Cell Lines 5.3
Gene expression of collecting duct carcinoma of the kidney 5.24
Transcriptional Profiling of Werner Syndrome (WS) iPSC-derived MSC and the isogenic gene-edited controls 5.05
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells [RNA-seq] 5.04
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells 5.04
Reprogramming of dermal papilla cell intact gene signature with 3D culture and Lef-1 overexpression 4.96
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 4.92
Gene expression profile of melanoma cell lines after overexpression or knockdown of KPC1 4.81
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates 4.79
Mutations in EBF3 disturb transcriptional profiles and cause intellectual disability, ataxia and facial dysmorphism 4.69
The DNA methylation landscape of human melanoma 4.53
The DNA methylation landscape of human melanoma [RNA-Seq] 4.53
Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas 4.5
Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas [RNA-seq] 4.5
Epigenetic Control of Skeletal Development by the Histone Methyltransferase Ezh2 4.37
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 4.15
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence 4.15
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 3.75
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 3.75
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 3.73
Transcriptome profiles of moderate dysplasia in oral mucosa associated with malignant conversion 3.73
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 3.64
RNA Expression Profile of Calcified Bicuspid, Tricuspid and Normal Human Aortic Valves by RNA Sequencing [BAV] 3.61
Expression profiling by RNA-Seq of breast cancer samples from patients in walnut-consuming and control groups 3.57
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 3.52
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 3.37
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 3.37
Derivation of ventrical and atrial cardiomyocytes and maturation using biowires 3.3
H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 3.19
RNA-seq of H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 3.19
C9/ALS Human Embryonic Stem Cells and C9/ALS Induced Pluripotent Stem Cells 3.11
Transcriptional profiling of healthy, eutopic and ectopic endometrial organoids 3.03
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels [RNA-Seq] 3.01
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels 3.01
Next Generation Sequencing identifying the dosage compensation state in human endometrial carcinoma and adjacent tissues 3.0
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity 3.0
Expansion of adult human pancreatic tissue yields organoids harbouring progenitor cells with endocrine differentiation potential 2.92
Identification of differentially expressed genes between senescence and senescence bypass cells 2.84
Fibroblasts in cholesteatoma activate osteoclasts. 2.71
Subcellular pathways shared by afflicted patients and mutant mice identify a new drug treatment for aortic aneurysm in Marfan syndrome 2.57
Effects of darunavir upon gene expression in kidney tubular cells after transduction with HIV or EGFP-control lentivirus 2.55
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 & MCM7 2.47
BMS-470539 on human synovial fibroblasts 2.47
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 2.45
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 2.35
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 2.33
The Promyelocytic Leukemia Zinc Finger Dependent Transcriptome during Human Endometrial Stromal Cell Decidualization 2.29
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  2.21
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 2.16
Patient-derived xenograft platform for metastatic melanoma: a model for studying resistance to targeted therapy. 1.97
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 1.81
Genome wide impact of loss of mechanoluminal stimulation on neonatal intestine 1.57
Divergent expression and metabolic functions of human glucuronosyltransferases through alternative splicing 1.42
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 1.2
DAOY-Notch1/Notch2 knockout: transcriptome comparison 1.08
Illumina Human Polycystic Liver Disease and Normal Biliary Stem Cell RNAseq 0.96
Gene expression regulated by CSA and CSB in neuroblastoma cell line 0.85
Whole transcriptome sequencing of the human thyroid primary cells with knock-down of the NRG1 gene 0.64
RNAseq of Breast cancer PDX samples 0.51
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG functional reactivation [human cells RNA-seq] 0.48
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG 0.48
Gene expression profiling of KSHV-infected periodontal ligament cells 0.42
Mutant p63 disrupts the key specification switch from the multipotent cell state to stratified epithelia during epithelial differentiation/in ectodermal dysplasia disorders 0.36
Macrophages redirect phagocytosis by non-professional phagocytes and influence inflammation 0.31
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation (RNA-Seq) 0.19
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation 0.19
Identification of miRNA-mRNA regulatory network for Human Atrial Aging 0.15
Identification of miRNA-mRNA regulatory network for Human Atrial Aging [mRNA] 0.15
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 0.14
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 0.13
Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes 0.12


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