Gene Query: SHC2

Dataset Description Geneva Score
Differentiation enhances Zika virus infection in neuronal brain cells 53.03
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 38.33
Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence 36.78
Lysine benzoylation is a novel histone mark 31.94
Lysine benzoylation is a novel histone mark [RNA-seq] 31.94
mRNA and RNC-mRNA deep sequencing of three hepatocellular carcinoma cell lines 26.82
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 23.38
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 22.95
Transcriptome analysis of ECFCs treated with GSK-343 and Panobinostat 21.93
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 20.89
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 20.1
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 20.1
Transcriptome variation among human embryonic stem cell lines impacts on their differentiation 18.54
The DPYSL2 gene connects mTOR and schizophrenia 18.4
Expansion, in vivo-ex vivo cycling and genetic manipulation of primary human hepatocytes 17.77
Endothelial Cells Control Pancreatic Cell Fate at Defined Stages through EGFL7 Signaling 16.37
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS 16.29
RNA sequencing of hPSC-derived cardiac progenitors and endocardium 15.58
Transcriptional profiling of microglia; current state of the art and future perspectives 14.96
Expression analysis of Mebendazole treated THP-1 cells in three paired samples 13.22
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 13.21
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 13.21
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 12.96
Capturing the biology of mild versus severe disease in a pluripotent stem cell-based model of Familial Dysautonomia 12.46
Rapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq) 12.33
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 11.27
Comparative Transcriptome analysis of hESCs- and iPSCs-derived lentoid body 11.22
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 10.38
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer 10.37
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer [RNA-Seq] 10.37
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 10.32
Telomere-Dependent and Telomere-Independent Roles of RAP1 in Regulating Human Stem Cell Homeostasis 9.65
RNA-seq of HBV-infected Primary Human Hepatocytes treatment by Tazarotene 8.86
EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling 8.42
A peninsular structure coordinates asynchronous differentiation with morphogenesis to generate pancreatic islets [bulk vs buds] 8.18
Self-organization of polarized cerebellar plate neuroepithelium in three-dimensional culture of human pluripotent stem cells 8.17
Global modulation of signaling pathways by SARM RAD140 in AR/ER+ breast cancer xenografts 8.02
Evaluating pre-clinical models for studying NASH driven HCC. 7.96
Engineering Patient-Specific Tissue Implants 7.95
A practical evaluation of alignment algorithms for RNA variant calling analysis 7.89
Comprehensive comparative analysis of RNA sequencing methods for degraded or low input samples 7.85
Nonpregnant and term pregnant human myometrial tissues 7.8
Transcriptomic profiles of nonpregnant and term pregnant human myometrial tissues 7.8
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation 7.69
RNA seq data of Hep3B-control, Hep3B-sertraline, Hep3B-XL413, Hep3B-XL413-sertraline, Huh7-control, Huh7-sertraline, Huh7-XL413, Huh7-XL413-sertraline cells 7.63
Generation of mature lung alveolar epithelial cells from human pluripotent stem cells 7.53
Transcriptional dependencies in diffuse intrinsic pontine glioma 7.49
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 7.44
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia 7.35
RNA-sequencing based transcriptome-wide expression profiling of Cynomolgus monkey and human IPSCs in vitro differentiated into endothelial cells 7.25
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 7.23
Total RNA sequencing of WT intestinal orgaonids. 7.07
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 7.05
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 7.05
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation 7.04
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 7.01
Analysis of transcrptomes of Danon patient derived hiPSC-cardiomyocytes by RNA-deep Sequencing 6.97
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 6.92
Rna-seq transcriptome data for insulin-GFP+ cells differentiated from NEUROD1 knock out and NEUROD1+/+ control human embryonic stem cells. 6.8
NEUROD1 dependent gene regulation in murine pancreatic endocrine cells and human stem cell derived insulin producing cells 6.8
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer 6.78
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray [RNA-Seq] 6.76
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray 6.76
Differetially expressed genes after hTR overexpression in U2OS cells 6.73
Identification of mesothelial-to-mesenchymal gene signature in ascitic fluid-isolated mesothelial cells through RNA-sequencing 6.69
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 6.58
Whole transcriptome RNA sequencing of human cells after HCV infection (ML-1 thyroid cell line, primary thyrocytes and Huh7.5 hepatocyte cell line) 6.44
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 6.28
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 6.26
Gene expression in mature and immature human ES-derived beta cells, and sorted beta-cells from adult islets 6.16
RNA-Seq analysis of neurons derived from induced pluripotent stem cells reprogrammed from dental pulp 6.16
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 6.13
Transcriptome analysis of human reninomas as an approach to understanding juxtaglomerular cell biology 6.11
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 6.1
Identification of gene signature in ascitic fluid-isolated mesothelial cells from high grade serous ovarian cancer patients 5.99
Detailed genomic and molecular characterization of Indian induced pluripotent stem cell lines 5.91
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells 5.87
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells [RNA-seq] 5.87
RNA-sequencing with micro-dissected boundary organoid into anterior, posterior, and boundary regions 5.84
Genome-wide Analysis of Human Constitutive Androstane Receptor (CAR) Transcriptome in Wild-type and CAR-knockout HepaRG cells 5.7
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes [RNA-Seq] 5.66
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes 5.66
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 5.65
Tamoxifen Resistance in Breast Cancer is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis 5.65
Next Generation Sequencing of human SMA and healthy control Motor Neurons 5.61
RNA-Seq profiling of days 0, 7 and 18 kidney organoids differentiated from three separate vials of starting material 5.58
Total RNA sequencing of APC mutant and wt colonic organoids 5.54
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration 5.52
Global gene expression differences between blood- and lymphatic-specific endothelial colony forming cells 5.46
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 5.45
Potential signaling pathways and gene signatures associated with brain metastases in NSCLC patients 5.44
Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming 5.43
Role of COP1 on MAP kinase transcriptional output in gastrointestinal stromal tumor 5.42
Differential susceptibility of human pleural and peritoneal mesothelial cells to asbestos exposure 5.36
Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas 5.34
RNA sequencing of BT142 and TS603 cell lines 5.34
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 5.24
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 5.19
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 5.18
The Wnt/β-catenin-signaling pathway is modulated by androgen ablation therapy for advanced clinical prostate cancer and contributes to androgen independent cell growth 5.17
Hepatitis C virus functionally sequesters miR-122 5.15
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 5.15
Role of FGFR1 in neuronal devlopment 5.11
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 5.08
Gene expression analysis of human hepatocellular cancers 4.98
Transcriptome profiling of HepG2 cells upon treatment of the menin-MLL inhibitor MI-503 or DMSO 4.96
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (22RV1 RNA-seq) 4.96
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability 4.96
Robust generation of honemogeneous midbrain organoids with in vivo–like cellular composition facilitates neurotoxin-based Parkinson’s disease modeling 4.93
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 4.92
Synaptic dysfunction in human neurons with Autism associated deletions in PTCHD1-AS 4.9
Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model 4.87
RNA seq with AML (NB4) cells upon FTO inhibition 4.87
Gene expression regulated by CSA and CSB in neuroblastoma cell line 4.81
Transcriptional responses of human insulinoma cells to acute cytokine exposure 4.79
Reconstruction of the Human Blood-Brain Barrier in vitro reveals a Pathogenic Mechanism of APOE4 in Pericytes 4.76
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 4.75
RNA-seq of young and quiescent MRC-5 human fibroblasts 4.75
Integrating the Epigenome to Identify Novel Drivers of Hepatocellular Carcinoma 4.71
Postnatal lipids drive hepatocyte maturation 4.7
De novo reconstruction of human adipose reveals conserved lncRNAs as regulators of brown adipogenesis 4.57
Next Generation Sequencing Analysis of human embryonic stem cells derived MESP1-mTomato reporter cells 4.53
DAOY-NERT2 Notch/Hypoxia Transcriptome Analysis 4.52
Development of an In Vitro Human Liver System for Interrogating Non-Alcoholic Steatohepatitis 4.45
Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium 4.42
RNA-seq of PC3 prostate cancer cell line xenografts in mice administered the ghrelin receptor antagonist [D-Lys3]-GHRP-6 or PBS for two weeks 4.38
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 4.33
Alagille_Nodder 4.27
RNA Seq of Alagille liver biopsies 4.27
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor 4.27
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 4.26
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 4.25
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 4.23
SETBP1-WT and SETBP1-G870S epigenetic landscapes 4.23
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 4.21
Connexin 32-mediated cell-cell communication is essential for hepatic differentiation from human embryonic stem cells 4.2
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 4.08
Gene expression changes after LOC550643 silencing 4.08
HNF1A deficiency impairs β-cell fate, granule maturation and function 4.03
Novel Targeting of Transcription and Metabolism in Glioblastoma 4.02
The effect of spontaneous acquisition of an extra chromosome 7 for engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 3.98
Enhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest 3.91
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived neurons 3.91
Reconstitution of the human pancreatic niche stimulates differentiation of hESCs into beta cells and reveals new signals for pancreatic endocrine cell maturation 3.87
Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21 3.77
RNA-sequencing of human liver tissue 3.72
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 3.7
RNA-Seq analysis of NKX2.2 knockdown in human pancreatic islets 3.68
NKX2.2 3.68
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation 3.68
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation (RNA-Seq) 3.68
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons 3.68
Loss of EGFR-DDEF1 signaling in metastatic and unresectable hepatoblastoma 3.66
Subtle asymmetry of gene expression in embryonic and foetal human brains 3.64
NGS based identification of GD2-positive tumor-specific phenotype for cancer diagnostics and therapy 3.64
circRNA-sequencing 3.62
Generating Patterned Kidney Organoids for Studying Development and Diseases 3.6
Total RNA sequencing of prospective axial stem cell cultures derived from human pluripotant stem cells 3.59
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 3.57
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 3.57
Transcriptome profiling of CXCR2+ neuroendocrine (NE) tumor cells purified from patients' fresh prostate adenocarcinoma 3.56
AR-independent prostate cancer is sustained through FGF signaling 3.56
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 3.56
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 3.56
Reversible LSD1 Inhibition with HCI-2509 induces the p53 gene expression signature in high-risk neuroblastoma cells 3.55
Genome-wide profiling of siRNA targeting EWS-FLI1 in TC32 Ewing sarcoma cell line 3.53
Next generation sequencing of advanced non-castrate prostate cancer treated with docetaxel chemotherapy 3.52
Effect of TUNAR silencing and GSK3 inhibition on human b-cell transcriptome 3.49
Oncogenic Serine-Threonine Kinase Receptor Associated Protein Supports Hepatocellular Carcinoma Cell Growth by Enhancing Wnt/β-catenin Signaling 3.49
Expression profiles of cultured human epididymis cells reveal the functional diversity of caput, corpus and cauda regions. 3.48
PRRX2 and HEY2 double knock-down facilitates ASCL1-induced neuron conversion in human dermal fibroblasts. 3.44
FGF2 regulation of gene expression in stable inducible Neurons 3.4
Hematopoietic Stem and Progenitor Cells from Human Pluripotent Stem Cells via Transcription Factor Conversion of Hemogenic Endothelium 3.39
DJ-1 is dispensable for human stem cell homeostasis 3.39
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 3.38
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 3.37
Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines 3.37
a-synuclein accumulation in an iPSC derived model of early onset sporadic Parkinson’s Disease reveals novel drug targets 3.32
Tracing transcriptome profiles of human oocyte cultured by growth hormone or not in vitro by single cell RNA-seq 3.31
Transcriptome analysis of virus infected tissues 3.25
Patient-derived luminal breast cancer xenografts with progestins 3.22
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 3.22
Disruption of GRIN2B impairs differentiation in human neurons 3.21
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes 3.17
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes [RNA-seq] 3.17
Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons 3.17
Human iPSC-based Modeling of Late-Onset Disease using Progerin-induced Aging 3.17
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 3.17
RNA-seq analysis of RALD iPSCs after in vitro differentiation 3.16
Genome expression analysis of Lung Progenitors matured in the presence of constitutively active or pharmacologically inhibited Glycogen Synthase Kinase 3 3.14
Effects on gene expression of ibrutinib treatment in human stem cells-derived atrial- and ventricular-like cardiomyocytes 3.14
Global gene expression differences between blood- and lymphatic-specific human dermal microvascular endothelial cells 3.13
SOX10 Single Transcription Factor Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells 3.12
yylncT acts as a gatekeeper of the mesodermal transcriptional program by local modulation of DNMT3B [human_2] 3.09
Gene expressions of H9s in different culture systems 3.08
CDK12 inhibition in Hep3B, Huh7 and SNU449 cells 3.06
Improved post thaw function and genetic changes for mesenchymal stromal cells cryopreserved using multicomponent osmolyte solutions 3.05
Next Generation RNA Sequencing Analysis of AMPK Wild Type, AMPKα-KO and AMPKα1-2A U2OS cell Transcriptomes 3.01
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 2.96
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 2.95
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 2.94
CUREfast: Accelerating research with families 2.93
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 2.91
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 2.9
Endothelial gene expression analysis 2.9
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 2.9
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 2.88
Analysis of the Clustered Protocadherin (cPcdh) Locus in Human Pluripotent Stem and Derived Cells [RNA-seq II our of II] 2.83
Organoids derived from directly reprogrammed human hepatocytes for modeling liver cancer initiation 2.82
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 2.8
Expression profiling of lncRNAs, miRNAs and mRNAs and their differential expression in leiomyoma using next generation RNA sequencing 2.8
CXCR4 is a host factor that regulates Plasmodium development in hepatocytes 2.79
In search for materials able to be colonized by a normal endothelium: сharacterization and NGS gene expression profiling of human primary endotheliocytes cultivated on electrospun 3D matrices 2.77
Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells [Bulk RNA-Seq] 2.77
iPSC derived motor neuron cultures from C9ORF72 carriers 2.71
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 2.7
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 2.7
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 2.68
The transcriptome and chromatin accessbility landscape of mammalian germline 2.68
RNA-seq of SCLC PDX models treated with EP 2.67
Hyper-excitability of Neurons generated from Patients with Bipolar Disorder 2.67
Gene expression patterns define the hepatocyte-like cells derived by different strategies [RNA-seq] 2.67
Gene expression patterns define the hepatocyte-like cells derived by different strategies 2.67
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 2.67
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 2.67
Integration of genome-wide DNA methylome and transcriptome of human intestinal fibroblasts reveals novel candidate gene signatures in Crohn’s disease-associated fibrosis 2.65
Paxillin regulates genomic networks in prostate cancer [LNCaP] 2.65
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 2.64
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 2.64
GATA2 is Dispensable for Generation of Hemogenic Endothelium But Required for Endothelial-to-Hematopoietic Transition 2.63
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 2.62
Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation 2.58
Hemogenic Endothelium transcriptome along the timeline of hESC differentiation 2.58
Zone dependent distinctive gene expression profile of the normal human liver tissue 2.57
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 2.55
Obstructed defecation – an enteric neuropathy? An exploratory study of patient samples 2.55
Transciptomic profiling of human fetal lung samples 2.54
ZNF804A transcriptome networks in differentiating human neurons derived from induced pluripotent stem cells 2.48
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 2.48
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 2.47
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HOM] 2.46
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 2.46
RNA-Seq Analysis in purified iPS cell-derived neuronal samples 2.44
Global analysis of enhancer targets: Mosaic-seq 2.42
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung [RNA-seq] 2.42
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung 2.42
Analysis of MGE Transcriptomes with or without Ctnnb1 knockout in human through RNA Sequencing 2.4
The expression profiles of GBC liver metastasis 2.39
Preliminary Report of Transplantation of Human Fetal Retinal Pigment Epithelial Cells on Age-related Macular Degeneration Patients 2.38
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes 2.38
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 2.37
Depicting early human development and germ cell origin with porcine embryos 2.36
Zika virus directly infects human peripheral neurons and induces cell death 2.36
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 2.32
STX4 Over-Expression in Human islets 2.3
RNA-Seq in PWS iPSC-derived neurons 2.28
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration 2.27
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 2.27
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 2.27
Genome-wide chromatin analysis of Ewing sarcoma 2.27
High level DNA repair gene expression in human ES cells 2.25
Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells 2.22
Transcriptome data from human endocrine cells recovered from mouse grafts with pre-engraftment controls 2.22
A single-cell atlas of the human cortex reveals drivers of transcriptional changes in Alzheimer’s disease in specific cell subpopulations 2.2
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 2.18
RNAseq to determine whether bidirectional transcription occurs over transposable elements following depletion of SETDB1 in THP-1 AML Cells 2.17
Single-Cell reconstruction of differentiation trajectory reveals essential dynamics in human cardiac lineage commitment 2.16
Adaptive chromatin remodeling in glioblastoma stem cell plasticity and drug tolerance 2.15
Human iPSC-derived glomeruli provide an advanced model to interrogate podocyte biology and accurately recapitulate podocytopathy 2.14
RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues 2.12
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs 2.11
The Cushing's disease adipose gene expression profile reveals effects of long term glucocorticoids on adipose tissue lipid, protein and glucose metabolism 2.11
Patient Derived Xenograft for Delivery of Precision Medicine in Castrate Resistant Prostate Cancer 2.11
Gene expression profiling of iPSC-derived cardiomyocytes with BAG3 mutations 2.1
Induction of Sertoli-like cells from human fibroblasts by NR5A1 and GATA4 2.1
Functional Haploid Human Oocytes Generated from Polar Body Genomes (RNA-Seq) 2.1
Functional Haploid Human Oocytes Generated from Polar Body Genomes 2.1
Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells 2.1
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 2.09
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 2.08
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism. 2.07
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism: Liver RNA profiles of lean non-diabetic, obese non-diabetic as well as obese diabetic humans. 2.07
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators 2.07
RNA Seq data: A375, A375R, A375DR vorinostat treated, and biopy samples from patients pre- and post- treated with Vorinostat 2.05
An acquired vulnerability of drug resistant melanoma with therapeutic potential 2.05
Evolution of an lncRNA leads to a primate specific modulation of alternative splicing 2.04
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros 2.04
A robust qualitative transcriptional signature for the early diagnosis of gastric cancer 2.01
Derivation and differentiation of haploid human embryonic stem cells [RNA-Seq 1] 2.01
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 2.01
Defective transcription elongation in a subset of cancers confers immunotherapy resistance 2.0
Effect of estrogen (E2) treatment on the C4-12 relative to the MCF7 cells 1.96
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 1.9
Short-term effect of Boost versus Radical doses of Intraoperative electron Radiotherapy in breast cancer tumor bed using high-throughput approaches 1.9
Reprogramming postnatal human epidermal keratinocytes toward functional neural crest fates 1.9
RNA sequencing of prostate cancers reveal insights on the prognostic significance of visibility on multi-parametric MRI 1.89
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 1.89
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 1.89
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 1.89
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [RNA-seq] 1.87
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 1.86
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 1.86
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 1.86
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer 1.86
Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease 1.85
Next Generation Sequencing Facilitates Quantitative Analysis of mesoderm posterior bHLH transcription factor 1(MESP1)+ and MESP1- cells' Transcriptomes 1.85
Identification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq 1.84
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 1.84
Mutations in EBF3 disturb transcriptional profiles and cause intellectual disability, ataxia and facial dysmorphism 1.83
MYCL and EP400 are required for Max and MCPyV mediated gene activation 1.81
TGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity 1.8
Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells 1.8
Integrated Multi-omic Analysis of Esthesioneuroblastomas Identifies Two Subgroups Linked to Cell Ontogeny 1.8
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 1.79
Discovering human diabetes-risk gene function with genetics and physiological assays 1.79
FMR1 reactivating treatments in Fragile X iPSC-derived neural progenitors in-vitro and in-vivo 1.78
Transcriptomics analysis of enteroendocrine cells following vertical sleeve gastrectomy 1.77
Transcriptomics analysis of human jejunal enteroendocrine cells after vertical sleeve gastrectomy 1.77
RNA-seq of human iPS derived macrophages with or without KLF1- transcription factor Activation 1.76
Canonical and non-canonical regulatory roles of androgen receptor variant 7 in prostate cancer 1.74
Transcriptomic analysis of human iPS cells derived from fragile X syndrome patients during neural differentiation 1.73
Differential responses of human fetal brain neural stem cells to Zika virus infection 1.72
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells 1.71
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells [RNA-seq] 1.71
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 1.71
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 1.71
Gene expression profile of CRC-derived HILEC 1.69
Reduced CYFIP1 in human neural progenitors as 15q11.2 deletion model: donor specific dysregulation of schizophrenia/epilepsy genes 1.67
RNA-seq analysis of the human fetal kidney. 1.67
Maturing an Enteric Nervous System in Human Intestinal Organoid-derived Tissue-Engineered Small Intestine 1.66
Deep sequencing of transcript levels in pluripotent stem cells and their differentiated derivatives in all three germ layers 1.61
Effect of circPTPRM on the biological behaviors of hepatocellular carcinoma cells in vitro and its clinical significance. 1.6
Critical role for Lymphocytes in Producing FLT3LG in Tumors and Driving Checkpoint Therapy-Receptive Immune Microenvironments 1.6
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 1.58
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 1.58
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 1.58
Expression profiling and occupancy after knockdown or over-expression of HFN1A or HNF4G in prostate cancer cells 1.55
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (LNCaP RNA-seq) 1.54
RNA profiling Analysis of the Serum Exosomes Derived from Active and Latent M.tuberculosis infectious Patients 1.52
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 1.51
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 1.5
RNA sequencing (RNA-SEQ) of EPAS1 knockdown by siRNA in endothelial cells 1.5
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 1.48
Human embryonic stem cells in E8 and AKIT culture medium 1.48
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 1.48
Reprogrammed myeloid cell transcriptomes in NSCLC 1.47
The Glioma-Infiltrating T Cell Receptor Repertoire 1.43
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 1.42
MEK inhibition rewires enhancer landscapes in RAS-driven Rhabdomyosarcoma to unlock a myogenic differentation block 1.42
Epigenetic Reprogramming of mutant RAS-driven Rhabdomyosarcoma via MEK Inhibition 1.42
Arnica montana stimulates extracellular matrix gene expression in human macrophages differentiated to wound-healing phenotype. Tested on 5 concentrations. 1.4
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency 1.39
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 1.38
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 1.38
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 1.37
Hepatic transcriptome of pediatric hepatoblastoma. 1.37
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [d7+d14] 1.37
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 1.36
GIST cell cycle dysregulation is required for progression to high-risk disease but not for resistance to kinase inhibitors 1.36
Comparative transcriptome analysis reveals that ECM-Receptor Interaction contributes to the venous metastases of hepatocellular carcinoma 1.36
mRNA-Seq profiling SIX2+ and Foxd1+ cells in mouse embryonic and SIX2+ and SIX2-/MEIS1+ cells human fetal kidney 1.34
Global gene expression profiles of cardiomyocytes differentiated from human pluripotent stem cells (hiPSC-CMs) in 3D culture exposed to ethanol 1.34
Gene expression profiling of patient's DCIS-IDC tandem lesions by RNA sequencing analysis 1.27
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 1.26
Novel kinase fusion oncogenes in post-Chernobyl radiation-induced pediatric thyroid cancers 1.23
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 1.23
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 1.23
A single-cell transcriptome atlas of the human pancreas 1.23
RNA-seq analysis of gene expression patterns during hESC neural differentiation 1.23
hESC neural differentiation 1.23
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of human mesenchymal stem cells differentiation from human embryonic stem cells and adult bone marrow mesenchymal stem cells 1.21
Derivation and differentiation of haploid human embryonic stem cells 1.21
Genome-wide identification of cancer-specific alternative splicing in circRNA 1.2
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 1.2
Human ovarian granulosa cell transcriptome 1.18
A genomic study of the contribution of DNA methylation to regulatory evolution in primates 1.16
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability 1.13
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability [RNA-Seq] 1.13
Functional astrocytes differentiated from hiPSCs 1.12
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 1.11
Human islets of varying quality: the good, the (not so) bad and the ugly 1.11
Discovery and verification of liver cancer marker genes and variable scission based on second-generation sequencing data analysis 1.11
Expression charcaterization of an internal protocol developed to differentiate RPE cells 1.11
mRNA expression data from ESCs derived by polar body transfer reconstructed embryos (PBTESCs) 1.05
Gene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4 1.05
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors 1.05
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 1.04
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 1.04
Non-coding and coding transcriptional profiles are significantly altered in pediatric Retinoblastoma tumors 1.02
Molecular pathogenesis of human prostate basal cell hyperplasia reveals a keratinocyte metaplasia 1.01
RNA-Seq analysis of human colorectal cancer with liver metastasis 1.0
circNFIB suppresses lymphatic metastasis of pancreatic cancer 1.0
RNA-Seq of Kaposi’s sarcoma reveal alterations in glucose and lipid metabolism 0.97
Deep sequencing of transcript levels of human embryonic stem cell derived mesothelium (epithelial and mesenchymal forms) and mesothelium from neonatal mouse E15.5 of the heart, lung, liver and gut and ChIP-seq data of the mesenchymal form of mesothelium 0.95
Gene expression analysis upon mtDNA depletion 0.94
Gene expression analysis upon mtDNA depletion [RNA-seq] 0.94
RNA-Seq characterization of human H1-derived NPC differentiation timecourse 0.93
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 0.92
RNA-seq in endometrial stromal tumors 0.91
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 0.91
Whole transcriptome sequencing of the human thyroid primary cells with knock-down of the NRG1 gene 0.89
CRISPR-mediated deletion of prostate cancer risk-associated CTCF loop anchors identifies repressive chromatin loops 0.88
RNA-sequencing 0.86
CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Humans 0.86
The expression of genes encoding palmitoylated proteins in axonal and synaptic compartments is affected in CLN1/PPT1 transfected neuronal cells 0.85
eRNA: A graphic user interface-based tool for RNA sequencing data analysis [mRNA-Seq] 0.83
eRNA: A graphic user interface-based tool for RNA sequencing data analysis 0.83
Transcriptome sequencing identify a recurrent CRYL1-IFT88 chimeric transcript in hepatocellular carcinoma 0.83
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 0.82
Glucose inhibits cardiac maturation through nucleotide biosynthesis 0.82
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.8
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 0.8
Single-cell survey of human lymphatics unveils marked endothelial cell heterogeneity and mechanisms of homing for neutrophils 0.8
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 0.77
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 0.77
The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC derived cardiomyocytes. 0.73
The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma [RNA-Seq Tumor] 0.72
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 0.72
Transcriptomics profiling of Alzheimer’s disease reveal novel molecular targets 0.72
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity 0.71
Human optic chiasm from healthy controls and multiple sclerosis patients 0.7
Multiple sclerosis and EAE 0.7
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 0.7
Interferon receptor signaling pathways regulating PD-L1 and PD-L2 expression 0.7
RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas 0.7
Generating Patterned Kidney Organoids for Studying Development and Diseases [bulk RNA-Seq] 0.69
The global transcriptome analysis in the time course of hESC-derived cardiac differentiation 0.69
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 0.69
Identification of miRNA-mRNA regulatory network for Human Atrial Aging [mRNA] 0.65
Identification of miRNA-mRNA regulatory network for Human Atrial Aging 0.65
BI Human Reference Epigenome Mapping Project 0.64
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 0.64
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 0.63
Gene expression profiling of papillary thyroid cancer from central and invasive regions 0.63
Profiling gene expression changes in primary ovarian tumors compared to matched normal fallopian tubes 0.63
Transcriptomic Dynamics during Differentiation Process of Human Pluripotent Cells into Hepatocyte-like Cells 0.62
Targeted differentiation of regional ventral neuroprogenitors and related neuronal subtypes from human pluripotent stem cells 0.62
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 0.62
Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular 0.6
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 0.59
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 0.59
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 0.59
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 0.58
RNA-seq of naive and primed ES cells 0.57
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas 0.55
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas [Human RNA-Seq] 0.55
Meta-organization of Translation Centers Revealed by Proximity Mapping of Endoplasmic Reticulum Ribosome Interactors 0.55
Concomitant BCORL1 and BRAF mutations in vemurafenib-resistant melanoma cells 0.55
Expansion of adult human pancreatic tissue yields organoids harbouring progenitor cells with endocrine differentiation potential 0.52
Comparison of small cell lung cancer PDX model FHSC04 for response to LSD1 inhibitor RG6016/ORY1001 0.48
Vitamin C dependent KDM6 demethylation specifies a functional chromatin state for endothelial-to-hematopoietic transition [RNA-Seq] 0.47
Vitamin C–dependent lysine demethylase 6 (KDM6)-mediated demethylation promotes a chromatin state that supports the endothelial-to-hematopoietic transition 0.47
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 0.47
Generation of Brain Region-specific Organoids using a Miniaturized Spinning Bioreactor and Modelling ZIKV Exposure 0.46
Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence. 0.46
Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells 0.44
Molecular analysis of renal cell carcinoma with unclassfied histology [gene expression] 0.44
Molecular analysis of renal cell carcinoma with unclassfied histology 0.44
Distinct Pathological Signatures in Human Cellular Models of Myotonic Dystrophy Subtypes 0.42
Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain 0.4
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 0.39
The MEF2B Regulatory Network 0.35
The MEF2B Regulatory Network - RNA-seq data 0.35
Cellular recruitment by podocyte-derived pro-migratory factors in assembly of the human renal filter 0.34
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 0.32
Single-Cell Transcriptome Analysis of Lineage Diversity and Microenvironment in High-Grade Glioma 0.31
Transcriptional Profiling of Werner Syndrome (WS) iPSC-derived MSC and the isogenic gene-edited controls 0.3
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.28
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 0.28
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 0.28
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (BGI12 RNA-Seq) 0.27
Identification of epigenetic interactions between miRNA and DNA methylation associated with polycystic ovarian syndrome 0.26
Transcriptome Profiling Reveals the key genes and pathways involved in polycystic ovary syndrome [RNA-seq] 0.26
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes [RNA-seq] 0.25
Gene expression and chromatin organization changes in lamin A/C haploinsufficient human induced pluripotent stem cell-derived cardiomyocytes 0.25
Screening in Human Cardiac Organoids Identifies a Requirement for the Mevalonate Pathway in Cardiomyocyte Proliferation 0.21
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 0.21
Quantitative profiling of the UGT transcriptome in human drug metabolizing tissues [Total RNA] 0.18
Preclinical model of obesity and ER-positive breast cancer 0.16
Genome wide impact of loss of mechanoluminal stimulation on neonatal intestine 0.15
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma 0.15
Transcriptome profiling of omental adipose tissues in human obesity by RNA-Seq 0.14
FOXA1 Chromatin Binding is Regulated by LSD1-Mediated Demethylation 0.13
RNA-Seq with DHT induction and/or GSK treatment at 24, 48 hrs and 2 weeks 0.13
Identification of microRNA-dependent gene regulatory networks driving human pancreatic endocrine cell differentiation [RNA-Seq III] 0.12
RNA sequencing of human pancreatic cancer cell lines 0.11
RNA sequencing of heart samples of myotonic dystrophic (DM1) patients 0.1
The control of rRNA synthesis during the directed differentiation of human embryonic stem cells precedes heterochromatin formation. 0.1
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 0.09
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations 0.08
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq] 0.08
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 0.08
RNA-seq analysis of uveal melanoma cells treated with FR900359 0.07
RNA sequencing of hiPSC derived neural crest populations from Familial Dysautonomia patients 0.07
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 0.07
Dissecting neural differentiation regulatory networks through epigenetic footprinting 0.06
Persistence of stem cell metabolism in cancers as a failure of differentiation 0.03
hNSCs siRNA NOVA2 0.03
Gene Expression Profile of human hepatocellular carcinoma by RNA sequencing 0.03
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue 0.01


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