Gene Query: SHQ1

Dataset Description Geneva Score
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 29.07
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 26.06
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 25.53
Transcriptome analysis of Jurkat T-ALL clones from control and CBAP-knockdown/knockout sets 24.87
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 22.22
Hijacking of stress response machinery by oncogenes in acute leukaemia 20.94
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 20.94
Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation 19.26
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 18.92
HEK293 TFAM Knockout Expression Study 17.98
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 16.88
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 16.88
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 15.38
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo 13.61
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo [RNA-seq] 13.61
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [short_hairpins_RNA-seq] 12.7
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 12.17
ETV7 and interferon response 12.17
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 12.09
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 11.65
Oncogenic MYC induces a dependency on the spliceosome in human cancer 10.72
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 10.28
Gene expression changes associated with resistance to tagraxofusp (SL-401) 9.09
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 8.95
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia 8.49
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 8.29
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 8.16
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-seq of KLF6 KO) 6.96
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 6.57
RNAseq of T-ALL upon long non coding rna purturbation 6.55
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 6.44
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 6.44
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 6.38
The lung-enriched p53 mutants V157F and R158L/P regulate a novel transcriptome in lung cancer 6.34
FBXW7 modulates stress response by post-translational modification of HSF1 6.11
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 6.11
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 6.05
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 6.04
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 6.02
BCL11B 5.72
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 5.63
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 5.59
Transcriptome of melanoma cell lines resistant to inhibition of the MAPK pathway. 5.55
The cohesin complex prevents Myc-induced replication stress 5.46
RNAseq of HEK293 cells after Chtop knockdown 5.46
Co-transcriptional loading of RNA export factors shapes the human transcriptome 5.46
Sequence dependency and regulatory function of dimeric NOTCH1/RBPJ complexes on coding and non-coding transcription in T-lymphoblastic leukemia 5.36
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 5.13
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 5.06
Integration of kinase and calcium signaling at the level of chromatin underlines inducible gene activation in T cells 4.95
Transcriptome-wide identification of CELF2 functional targets in T cells 4.94
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 4.84
A transcriptome-wide divergence in protein translation scales with LIN28B expression 4.78
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 4.76
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 4.75
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [GSKJ4_RNA-seq] 4.6
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 4.59
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 4.57
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance 4.57
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 4.49
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 4.47
LncRNA-GAS5 negative regulation of YAP-target genes expression 4.42
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 4.39
Gene expression alterations associated with acquired-resistance to the CDK4/6 inhibitor palbociclib [Palbociclib resistance_RNASeq] 4.38
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 4.38
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 4.26
mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II transcription 4.18
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 4.17
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 4.17
RNA-Sequencing experiment for effects of PKF115-584 treatment on four T-ALL cell lines (RPMI8402, HPB-ALL, Jurkat, CCRF-CEM). 4.14
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 4.07
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 4.07
Next generation sequencing on knockdown of AC093323.3 in lung cancer cells 4.07
Transcription differences in DLBCL cell lines U2932, DOHH2 on treatment with TK compound compared to DMSO 4.02
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 4.02
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 3.97
Analysis of transcriptomes of healthy donor and CD46 deficient CD8 T cells 3.95
Transcriptome analysis of CD8+ T cells from healthy controls and patients wth CD46 deficiency 3.95
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 3.93
Transcriptome analysis of dominant-negative Brd4 mutants identifies Brd4-specific target genes of BET inhibitor JQ1 3.9
The landscape of alternative splicing in aggressive prostate cancers 3.85
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 3.84
Transcriptome of activated human and mouse MAIT cells 3.83
BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors 3.79
Trans-differentiation of human adult peripheral blood T cells into neurons 3.78
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 3.72
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 3.63
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 3.63
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 3.61
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 3.61
Human T-cell lymphoblastic lymphoma samples and control thymuses 3.6
RNA-Seq in human T-cell lymphoblastic lymphoma samples and control thymuses 3.6
Downregulation of DDX5/DDX17 and REST 3.57
The Genetic Landscape of Diamond-Blackfan Anemia 3.57
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 3.56
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling 3.55
RNA-seq analysis of control and Myc-induced U2OS cells 3.53
Specific inhibition of DPY30 activity by peptides suppresses blood cancer cell growth 3.48
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 3.47
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 3.46
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 3.46
Identification of global regulators of T-helper cell lineage specification 3.46
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 3.46
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 3.45
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 3.43
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 3.43
Transcriptomic profile of T cell acute lymphoblastic leukemia (T-ALL) cell from patients in CHCQMU 3.38
miR-191 regulates human cell proliferation and directly targets multiple oncogenes [seq] 3.37
Genome wide miR-191 target profile determined by RIP and gene expression profiling 3.37
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 3.37
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 3.37
Transcription control by the ENL YEATS domain in acute leukemia 3.32
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 3.32
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 3.32
MicroRNA (miR)-211 loss promotes metabolic vulnerability and BRAF inhibitor sensitivity in melanoma 3.31
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 3.31
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 3.3
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 3.3
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 3.3
DART-seq: an antibody-free method for global m6A detection 3.23
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 3.19
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 3.18
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 3.15
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 3.15
KSDM1b Role in Ewing Sarcoma 3.14
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 3.13
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 3.11
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression 3.1
HNF1A deficiency impairs β-cell fate, granule maturation and function 3.07
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 3.07
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 3.06
transcriptomic profiling of HEK293 cells upon individual knockdown of the splicing factors RBM17, U2SURP or CHERP 3.06
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 3.04
MYC dependent mRNA translation shapes gene expression and cell biology 3.03
Cajal bodies are linked to genome conformation [RNA-Seq] 3.02
Cajal bodies are linked to genome conformation 3.02
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia 3.0
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia (RNA-seq) 3.0
Systematic discovery of endogenous human ribonucleoprotein complexes 3.0
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 2.99
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 2.99
Transcriptome analysis in HT29 and SW480 cells depleted of Prdx2 2.92
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 2.92
HITS-CLIP analysis uncovers a link between the Kaposi's sarcoma associated herpesvirus ORF57 protein and host pre-mRNA metabolism 2.91
BRG1 governs Glucocorticoid Receptor interactions with chromatin and pioneer factors across the genome 2.89
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 2.89
RNA-seq data from human lymphoma cell lines 2.88
ChIP-seq and RNA-seq from human lymphoma cell lines 2.88
Salmonella activation of STAT3 signaling by SarA effector promotes intracellular replication and production of IL-10 2.88
Global transcriptional changes in U87MG glioblastoma cells upon shRNA-mediated TRIM52 knockdown 2.87
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 2.86
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 2.85
Transcriptional effect of ETV1 knockdown in melanoma cells 2.84
A Unique Epigenomic Landscape Defines Human Erythropoiesis 2.82
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 2.82
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 2.81
Comparison of single-cell transcriptomics quality between unfixed cells and cells that were fixed and mock stained according to the RAID procedure 2.8
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors 2.77
Low-Cell-Number, Single-Tube Amplification (STA) of RNAs Revealed miRNA Changes from Pluripotency to Endothelium 2.75
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 2.73
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 2.71
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 2.7
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 2.69
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 2.68
Wide-scale analysis of alternative polyadenylation (APA) associated with proliferation and transformation using 3'-Seq 2.68
H3K27ac ChIP-Seq and mRNA-Seq analysis of five human B-lymphoblastoid cell lines (LCLs) prepared from the same healthy male individual (CEPH/UTAH). 2.67
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations 2.67
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations [RNA-Seq] 2.67
RNA-seq analysis of differentiating human erythroblasts 2.66
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 2.65
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 2.65
Ro60-knockout cells 2.65
LNCaP treated with iBET 2.62
Total RNA-seq in ALL-SIL upon TLX1 knockdown 2.61
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 2.61
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 2.61
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 2.58
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 2.58
Integrative analysis of RNA, translation and protein levels reveals distinct regulatory variation across humans 2.56
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence 2.56
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 2.56
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 2.56
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 2.56
Genetic and pharmacological restoration of TET2 function blocks stem cell self-renewal and progression of leukemia 2.53
RNA-sequencing of human leukemia cells and mouse hematopoietic progenitors 2.53
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 2.51
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 2.49
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 2.47
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 2.47
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 2.47
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 2.47
Role of COP1 on MAP kinase transcriptional output in gastrointestinal stromal tumor 2.46
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 2.46
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells 2.44
Dynamics of MBD2 deposition across methylated DNA regions during malignant transformation of human mammary epithelial cells (2) 2.44
A sister of NANOG regulates genes expressed in pre-implantation human development 2.41
Integrating single-cell transcriptomic data across different conditions, technologies, and species 2.4
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 2.38
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 2.38
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 2.37
Osteogenic programming of adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the Polycomb protein EZH2 2.37
RNA-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 2.37
RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 2.37
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 2.37
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 2.36
PRDM1 inhibits proliferation of human colon cancer organoids 2.36
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 2.35
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 2.34
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 2.33
PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer 2.32
mRNA expression profile of Lymphocytes 2.32
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 2.32
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer [RNA-seq] 2.31
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer 2.31
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 2.3
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 2.24
Global analysis of alternative splicing regulated by RBM10 2.23
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers (RNA-Seq) 2.21
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers 2.21
Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects 2.21
MYCL and EP400 are required for Max and MCPyV mediated gene activation 2.2
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 2.19
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 2.18
Transcriptomic analyssis following EHMT1/2 inhibition 2.18
Integrated high-throughput screen to identify novel treatment leads for pediatric acute myeloid leukemia (AML) 2.18
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 2.18
RIG-I and MDA5 fRIP during KSHV lytic reactivation 2.15
RNA-Seq of cKIT+ sorted cells from 16-16.5 week old fetal testes and ovaries and RNA-Seq of TRA-1-60+ H1 hESCs 2.14
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 2.12
RNA-seq of resting and activated CD4+ T cells +-JQ1 2.11
Long non-coding RNA profiling of human lymphoid progenitors reveals transcriptional divergence of B cell and T cell lineages 2.11
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 2.1
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 2.09
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 2.09
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 2.09
Seletive inhibition of CDK9 in DLBCL cell lines 2.07
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 2.06
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity 2.06
Investigsting the role of NF-ĸB p50 S80 phosphorylation in regulating TNFα-induced transcription in HEK293T cells 2.05
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 2.05
HeLa transcriptome induction by IFN gamma and indoleamine 2,3-dioxygenase (IDO) 2.05
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 2.05
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 2.03
Dynamic 3D chromosomal landscapes in acute leukemia [RNA-Seq] 2.02
Dynamic 3D chromosomal landscapes in acute leukemia 2.02
Poly(A)-ClickSeq resolves CF25-mediated alternative poly-adenylation, HeLa 2.01
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 2.01
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 2.0
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 2.0
Silencing p300 in MCF7 cells to study expression and alternative splicing 2.0
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 1.97
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 1.97
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 1.97
SLIGRL-induced gene expression changes in NHEK cells 1.97
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 1.96
Gene expression changes in human melanoma cell lines compared to primary melanocytes 1.95
Glutaminolysis is a metabolic dependency in FLT3 ITD Acute Myeloid Leukemia unmasked by FLT3 Tyrosine Kinase Inhibition 1.93
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 1.93
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 1.93
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 1.92
Study functions of ADAR proteins using next generation sequencing of genome and transcriptome 1.92
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 1.9
RNA transcriptome analysis during HSV-1 infection 1.89
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 1.88
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 1.88
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 1.82
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 1.82
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 1.81
Flura-seq identifies organ-specific adaptations in metastasis-initiating cells 1.81
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP 1.81
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 1.8
Dissecting cell composition and cell-cell interaction network of normal human heart tissue by single-cell sequencing 1.79
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer 1.79
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer (RNA-seq) 1.79
Human Treg IFNg/IL-10 subpopulations 1.78
MAIT cell RNA sequencing 1.78
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 1.77
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 1.76
RNA-seq of YB5 cells treated with Proscillaridin A 1.76
Genome-wide Gene Expression Profiling in DLBCL Cell Lines Treated with CUDC-907 1.75
RNA expression profiling of human mPB or CB-derived CD34+ cells treated with UM171 at different doses 1.75
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (RNA-seq dataset) 1.74
KSHV vIRF3 promotes angiogenesis of lymphatic endothelial cells (LECs) 1.74
A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (RNA-Seq) 1.73
RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express either ER or ER-SOX4 with and without 4-OHT to induce nuclear translocation 1.72
Epigenome Editing by a CRISPR/Cas9-Based Acetyltransferase Activates Genes from Promoters and Enhancers 1.71
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 1.7
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 1.7
Knockdown of ADNP in HCT116 colon cancer cells 1.7
SNHG5 siRNA knock down in HCT116 cells 1.69
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 1.68
Gene expression signatures of innate lymphoid cells from human blood 1.68
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 1.68
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 1.67
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 1.64
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 1.62
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 1.62
Transcriptomic analysis of ERR alpha orphan nuclear receptor 1.61
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 1.6
Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells 1.59
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 1.59
RNAseq of human monocyte cell line (U937-Cas9) WT or IRF2KO 1.59
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 1.59
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 1.58
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 1.57
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 1.57
Gene expression profile in breast cancer cell lines using RNA sequencing 1.56
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 1.56
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 1.56
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 1.54
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 1.54
Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays 1.54
Dynamic gene expression in T-ALL following treatment and release of gamma-secretase inhibition [GRO-Seq] 1.52
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 1.51
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq] 1.5
Profiling of lung tumor-infiltrating CD8 T cells according to their expression status of CD39 1.49
N6-methyladenine DNA Modification in Glioblastoma 1.47
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 1.47
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 1.45
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 1.45
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 1.43
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 1.43
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 1.42
RNA-dependent RNA polymerase sequence specificities of capsnatching viruses are tailored to aid viral replication 1.41
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 1.39
Translating transcriptome of cancer cells in situ in mesenchymal-rich tumor microenvironment 1.39
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis 1.38
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia 1.38
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia [RNA-Seq] 1.37
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia 1.37
Real-time observation of light-controlled transcription in living cells 1.37
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 1.37
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 1.37
Transcriptome of TNF-a-treated and untreated HeLa cells before and after TFIIB knockdown 1.35
Therapy-induced hypoxia contributes to AML drug-resistance through BMX Kinase upregulation 1.34
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 1.34
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer 1.34
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks 1.33
β-Caryophyllene Enhances the Transcriptional Upregulation of SREBP-dependent Lipid Biosynthesis in Breast Cancer Cells 1.31
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 1.31
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 1.3
Next-generation RNA sequencing to determine changes in gene expression during breast cancer progression 1.3
Human Treg NaCl stimulation 1.27
Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and Natural Killer Cell Function 1.25
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 1.23
Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist 1.21
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 1.21
Landscape and variation of RNA secondary structure across the human transcriptome 1.2
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 1.18
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 1.17
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 1.16
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 1.16
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 1.16
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 1.14
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 1.13
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 1.12
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 1.12
RNA-Seq in PWS iPSC-derived neurons 1.11
single cell RNA-seq from Purkinje cell (ENCSR888LYA) 1.1
Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution 1.08
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 1.08
Human cell line and subcutaneous tumor 1.07
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 1.06
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 1.06
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 1.06
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 1.05
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 1.05
The transcriptome and chromatin accessbility landscape of mammalian germline 1.01
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 1.01
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 1.01
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 1.0
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 1.0
RNA sequencing with KSHV infection and enrichment for circular RNAs 0.99
Changes in CD34 and Erythroid Progenitor Transcriptome After RUNX3 Kock-down 0.97
SETBP1-WT and SETBP1-G870S epigenetic landscapes 0.96
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 0.96
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 0.96
Nascent RNA Sequencing after NMYC activation in SH-EP MYCNER cells 0.95
Identification of long noncoding RNAs in T-ALL cell lines 0.95
A20 regulates canonical wnt-signaling through an interaction with RIPK4 0.94
Human Adult Sorted Live Cell Erythroblasts RNA-Seq. 0.94
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 0.93
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 0.9
Effect of PRDM11 depletion in U2932 cells 0.89
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 0.89
Transcriptional landscape changes during human embryonic stem cell derivation 0.87
RNA-seq data 0.87
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 0.87
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 0.85
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 0.84
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 0.84
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 0.84
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 0.84
p53 activity results in DNA replication fork processivity 0.83
microRNAs with an AAGUGC seed motif constitute an integral part of a signaling network driving NSCLC cell proliferation 0.82
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 0.79
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on HepG2) 0.78
RNA-seq analysis of SKMEL28 melanoma cells following DIRC3 and IGFBP5 ASO knockdown 0.78
Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq 0.78
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 0.76
single cell RNA-seq from GM12878 (ENCSR673UIY) 0.74
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 0.72
Functional significance of the HIV-1 Tat signature amino acid residues 0.72
Transcriptome sequencing analysis of BRAF-mutant melanoma metastases. 0.71
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 0.71
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma 0.69
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells 0.67
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells (RNA-seq) 0.67
An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans. 0.66
Comparative Transcriptomic Analysis of Hematopoietic System Across Species by Microwell-Seq 0.66
Controlling for gene expression changes in transcription factor protein networks. 0.65
An siRNA screen identifies CHD4 as a target for epigenetic therapy 0.64
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 0.63
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 0.63
ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression 0.63
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.62
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 0.62
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 0.62
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 0.61
Effect of drugs on transcriptomic profiles 0.6
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 0.6
Generation and persistence of human tissue-resident memory T cells in lung transplantation 0.56
Human MAIT cells exit peripheral tissues and re-circulate via lymph in steady state conditions 0.56
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 0.56
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.55
RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer 0.54
O-glcnAc reprograms cellular energetics 0.54
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 0.53
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] 0.5
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 0.5
RNA G-quadruplexes mark repressive upstream open reading frames in human mRNAs 0.47
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 0.47
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.44
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 0.42
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 0.42
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 0.41
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 0.41
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 0.41
Modulation of nonsense-mediated decay by rapamycin 0.4
RNAseq of CD8+ and CD8- MAIT cells in human peripheral blood 0.4
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 0.39
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (scRNA-Seq) 0.39
Cap-specific terminal N6-methylation of RNA by an RNA polymerase II-associated methyltransferase. 0.38
Direct Isolation and Characterization of Human Nephron Progenitors. 0.37
RNA sequencing of T-ALL (COG study) 0.36
Analyses of T-ALL (COG study) 0.36
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 0.36
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 0.36
RB tumor suppressor promotes cancer immunity through downregulating PD-L1 expression 0.34
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 0.34
Oncogenic roles of ARID5B in T-ALL 0.34
RNA-seq analysis in knockdown Jurkat samples for each factor of TAL1 complex 0.34
High-resolution comparative analysis of great ape genomes 0.33
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.33
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.33
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 0.33
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 0.33
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.32
Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells 0.32
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 0.3
Genome-wide maps of WT and over-expressing CenH3/CENP-A in Human HeLa S3 cells 0.3
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 0.3
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 0.29
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 0.29
Impact of Escherichia coli K12 and O18 on human platelets: effects on platelet activation, spliced platelet RNAs and proteins 0.25
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 0.23
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 0.23
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 0.22
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 0.21
LKB1, Salt-Inducible Kinases, and MEF2C are linked dependencies in acute myeloid leukemia (RNA-Seq) 0.21
LKB1, Salt-Inducible Kinases, and MEF2C are linked dependencies in acute myeloid leukemia 0.21
Dissecting the single-cell transcriptome network underlying gastric premalignant lesions and early gastric cancer [10x genomics] 0.2
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 0.19
Polarized B -cell functions 0.19
Expression levels of genes of NKG2C+ NK cells after in vitro treatment 0.18
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.16
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.16
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 0.16
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 0.15
Identification of a LIF-responsive replication-competent human β cell 0.14
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 0.13
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.12
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 0.12
Transcriptional changes after overexpression of proliferation drivers in human mammary epithelial cells. 0.1
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 0.09
Human Treg IL-12 stimulation 0.09
Loss of CREBBP results in gene expression repression in lymphoma cells 0.08
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 0.08
Aberrant expression profile of lncRNA and mRNA in dilated cardiomyopathy by RNA-sequence 0.06
Single cell RNA-seq resolves lineage-specific activation dynamics of human blood and tissue T cells 0.06
Leucegene: ALL sequencing 0.05
hsa-miR-503, hsa-miR-103, and hsa-miR-494 genome wide target profiles [RNA-Seq and RIP-Seq] 0.05
Genome-wide hsa-miR-503, hsa-miR-103, and hsa-miR-494 target profiles 0.05
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 0.05
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 0.04
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.04
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 0.03
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 0.03
To identify transcripts that are differentially expressed in the MYCN amplified vs MYCN non-amplified cell lines using Next Generation Sequencing 0.03
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.02


Contact Us

For scientific and technical queries contact Butte Lab @UCSF


Cite GENEVA Tool

Manuscript in Preparation