Gene Query: SOX4

Dataset Description Geneva Score
Distinct epigenomes in CD4+ T cells of newborns, middle-ages and centenarians. 150.22
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 127.4
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 127.4
NAD+ Analog-sensitive PARPs Reveal a Role for PARP-1 in Transcription Elongation 114.07
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 105.4
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 105.4
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 99.58
Differential analysis of gene regulation at transcript resolution by RNA-Seq 98.03
Differential analysis of HOXA1 in adult cells at isoform resolution by RNA-Seq [Illumina] 98.03
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 96.5
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 96.5
ARID1A and ARID1B loss in HCT116 cells 95.65
Transcriptome analysis of human immortilized astrocytes reprogrammed into dopaminergic neurons 91.77
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 89.75
To investigate the decay constants (half-lives) of transcript isoforms generated by alternative polyadenylation in proliferating and quiescent cells 85.11
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 83.82
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 81.34
Differential expression of genes in AD169-infected MRC5. 80.0
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 79.16
circRNA-sequencing 78.62
Gene expression by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1.4 knock-down and multiple H1 variants 76.96
Defining a microRNA-mRNA targetome for calcineurin inhibitor induced nephrotoxicity 73.28
Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells. [RNA-Seq - ex vivo] 71.68
Expression profiling of lncRNAs, miRNAs and mRNAs and their differential expression in leiomyoma using next generation RNA sequencing 69.08
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 68.1
Genome wide mapping of polyadenylation sites in proliferating and contact-inhibited cells and cells with knockdown of cleavage and polyadenylation factors 68.02
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 67.74
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 66.94
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 66.94
Deletion of DXZ4 on the human inactive X chromosome eliminates superdomains and impairs gene silencing 64.67
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 64.55
A549 cells and MSR-A549 cells 64.29
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 64.29
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 62.06
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 59.04
iRNA-seq: Computational method for genome wide assessment of acute transcriptional regulation from total RNA-seq data 58.53
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 56.7
RNA helicase A is necessary for KIF1Bβ tumor suppression in neuroblastoma 56.45
Gene expression data from IMR90 control, IMR90 shRRM2 and shRRM2/shp16 54.32
SNHG5 siRNA knock down in HCT116 cells 53.51
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 52.56
Nrf2 regulated genes in A549 cells 52.04
Identification of Nrf2 regulated genes by RNA sequencing 52.04
MULTI-seq: Universal sample multiplexing for single-cell RNA sequencing using lipid-tagged indices 51.95
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 51.69
Gene expression changes upon drug withdrawal (Mel888 cell line) 50.47
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 49.63
Ebola virus (EBOV) infection of ARPE-19 cells 49.59
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 49.29
IL-33 activates tumor stroma to promote intestinal polyposis 49.12
RNA-Sequencing of human dermal lymphatic endothelial cells (HDLEC) treated with siRNA targeting YAP/TAZ and YAP5SA 48.69
Overexpression of PHF8 promotes an EMT-related gene signature in MCF10A cells 48.64
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 47.82
Improved post thaw function and genetic changes for mesenchymal stromal cells cryopreserved using multicomponent osmolyte solutions 47.7
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 47.05
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 46.12
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 46.12
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 44.91
Rorc disruption in human FG pancreatic cancer cells 43.67
SETDB1 compacts the inactive X chromosome in part through silencing an enhancer in the IL1RAPL1 gene 42.43
Rational targeting of cooperating layers of the epigenome yields enhanced therapeutic efficacy against AML 42.17
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 41.38
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 40.25
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 40.04
SRSF2 mutations impair hematopoiesis and alter exon recognition 39.69
Landscape of human mast cell chromatin: a rich resource for identification of novel mediators and genetic drivers of allergic and inflammatory diseases 39.56
Transcriptomic profiling of human CD34+ derived mast cells [RNA-Seq] 39.56
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte [RNA-seq] 39.15
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte 39.15
Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq 39.02
Telomere-Dependent and Telomere-Independent Roles of RAP1 in Regulating Human Stem Cell Homeostasis 38.83
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 38.68
Global transcriptomic analyses of bronchial epithelial cells exposed to 5 ng/mL TGF-β1 and 10 nM Estrogen individually and in combination 38.65
BRG1 governs Glucocorticoid Receptor interactions with chromatin and pioneer factors across the genome 38.62
Transcriptomic profiling of nasopharyngeal carcinoma (NPC) and normal control samples 38.52
Transcriptomic profiling of mRNA and miRNA from nasopharyngeal carcinoma (NPC) and normal control samples 38.52
Transcription profile analysis of wild type and Irf9-/- human monocytic THP1 cells in response to type I interferons 38.3
Irf9 function in immunity in mouse 38.3
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 38.21
Silencing p300 in MCF7 cells to study expression and alternative splicing 38.01
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 37.52
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 37.48
Single-nucleotide-resolution mapping of HBV promoters using CAGE 37.43
Epigenetic reprogramming at estrogen-receptor binding sites alters the 3D chromatin landscape in endocrine resistant breast cancer [RNA-seq] 37.18
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine resistant breast cancer 37.18
DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes 36.66
Transcriptome-wide identification of CELF2 functional targets in T cells 36.25
Enriched EWSR1 and EWS-FLI1 RNA-seq of HNRNPH1-silenced TC32 Ewing sarcoma and 293T human embryonic kidney cells. 36.09
Quantitative Analysis of negative control and overexpression-TRIB1 in PC3 and DU145 Transcriptomes 36.07
Stably-paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor Triptolide 35.96
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 35.9
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells 35.78
Inhibition of TNBC metastasis by Gpx1 35.73
RNA-seq analysis of SLIRP knockdown with 1nM DHT in LNCaP cells 35.71
Real-time observation of light-controlled transcription in living cells 34.95
Transcriptomic profile of T cell acute lymphoblastic leukemia (T-ALL) cell from patients in CHCQMU 34.91
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 34.8
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 34.74
RNA-sequencing of human peripheral blood mononuclear cells (PB MNCs) and induced neural progenitor cells derived from PB MNCs 34.68
Decrease in EZH2 histone methyltransferase mediates the effects of fluid shear stress (FSS) in endothelial cells 34.42
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 34.12
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 33.87
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 33.62
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 33.39
The transcriptomic landscape of MAIT cell development in the thymus (C006 RNAseq data set) 33.39
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 33.33
RNA-seq of human aneuploid cell lines with Trisomy 21 33.25
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-seq of KLF6 KO) 33.19
33.01
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 32.94
Transcriptional profiles of human blood dendritic cell (DC) subsets at steady state 32.46
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 32.13
Transcriptome-wide analysis of the role of HTLV-1 Tax PBM in T-Cells from infected humanized-mice (hu-Mice) 32.11
Comprehensive RNA sequencing of healthy human endometrium at two time points of the menstrual cycle 32.0
RNA sequencing of GlyH-101-treated MCF-7 cell line 31.97
Lung Cancer Cell-Mediated Skeletal Muscle Mitochondrial Dysfunction is Mitigated by 1a,25-Dihydroxyvitamin D3 31.58
Analysis by Whole Transcriptome Sequencing of the Effects of LLC1 conditioned medium, LLC1 conditioned plus Calcitriol, non-conditioned medium, and non-conditioned medium plus Calcitriol on mRNA Expression in Primary Human Skeletal Muscle Cells 31.58
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 31.15
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 31.15
Effects on gene expression of ibrutinib treatment in human stem cells-derived atrial- and ventricular-like cardiomyocytes 31.15
The Role of Histone H3 Lysine 36 Methylation in Reprogramming of fibroblasts and on Induced Pluripotent stem Cell Generation 30.99
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 30.78
Expression profile of LNCaP/AR cells with or without HNF4G expression grown for long term in charcoal stripped-serum (CSS) media 30.78
Transcriptome analysis in a radiosensitive and a radioresistant cell line after ionizing radiation 30.74
ZNF131 suppresses centrosome fragmentation in Glioblastoma stem-like cells through regulation of HAUS5 30.65
DJ-1 is dispensable for human stem cell homeostasis 30.64
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 30.62
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer 30.49
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer [RNA-seq] 30.49
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells [RNA-Seq] 30.44
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells 30.44
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 30.35
H1609088 Human RNA-Sequencing 30.34
Investigation about fibroblasts of different origins in culture 30.09
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia [RNA-Seq] 29.74
Endogenous retroviruses are a source of oncogenic enhancers in acute myeloid leukemia 29.74
PER2 synchronizes mitotic expansion and decidual transformation of human endometrial stromal cells 29.41
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq 28.88
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq and microarray 28.88
Control of prostate tumour growth by the long non-coding RNA GHSROS 28.75
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 28.63
Human ovarian granulosa cell transcriptome 28.54
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 28.49
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 28.36
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 28.24
Genome-wide analysis of STAT3 in diffuse large B-cell lymphoma 28.19
mRNA and miRNA expression in primary human muscle cells treated with 1,25(OH)2D3 or vehicle 28.09
RNA expression in primary huamn muscle cells treated with 1,25(OH)2D3 or vehicle 28.09
Effect of TUNAR silencing and GSK3 inhibition on human b-cell transcriptome 28.02
RNA-seq data from human lymphoma cell lines 27.95
ChIP-seq and RNA-seq from human lymphoma cell lines 27.95
Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers 27.76
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 27.55
High-throughput RNA sequencing on circular RNA profiles of human triple-negative breast cancer and adjacent normal tissues 27.41
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 27.12
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 27.12
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 27.06
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 26.89
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging 26.55
Inhibition of the Aryl Hydrocarbon Receptor - Polyamine Biosynthesis Axis Suppresses Multiple Myeloma and prostate cancer progression 26.43
Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing 26.42
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 26.42
RNA-Seq gene profiling comparison from human cDC subsets and pre-cDC subsets 26.33
SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors 26.17
Gene expression analysis of ER+ and ER- breast cancer cell lines with acquired resistance to palbociclib 26.12
Insights into snoRNA biogenesis and processing from PAR-CLIP of snoRNA core proteins and small RNA sequencing 25.79
Generation of trichogenic adipose-derived stem cells by expression of three factors 25.78
A novel non-canonical signaling pathway mediates TGF-β1-induced glucocorticoid insensitivity in epithelial cells 25.68
Fixed tissue ChIP-Seq (FiT-Seq) of archived clinical samples reveals chromatin dynamics and tumor-specific enhancer profiles 25.58
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO] 25.48
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 25.46
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 25.15
RNA-Seq Analysis of Anacardic Acid Treated MCF7 and MDA-MB-231 Breast Cancer Cell Lines 25.07
Gene expression in PANC1 cells treated with Rakicidin 25.07
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 24.9
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 24.89
Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells 24.76
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived SPINK1 24.74
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 24.68
GIST cell cycle dysregulation is required for progression to high-risk disease but not for resistance to kinase inhibitors 24.62
Single Cell RNA-Sequencing Identifies Diverse Roles of Epithelial Cells in Idiopathic Pulmonary Fibrosis 24.52
RNA-Seq of human PDA cell lines transfected with control siRNA or Pdx1 siRNA 24.52
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on PANC1 cells treated with CoCl2) 24.41
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 24.41
Multiple roles for Grainyheadlike transcription factors in the establishment and maintenance of human mucociliary airway epithelium 24.15
Evolved Labels of Placental Invasion in Human and Bovine Endometrial Stroma 24.13
PTP4A1 phosphatase is overexpressed in systemic sclerosis fibroblasts and promotes TGFb signaling 24.12
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and SMAD4 Y95 Mutation Transcriptomes 24.08
Exploring the role of macroH2A1 in transcription regulation in IMR90 primary human lung fibroblasts with RNA-seq and ChIP-seq 24.0
RNA-seq from control and macroH2A1-depleted IMR90 primary human lung fibroblasts 24.0
Epigenomic landscape during organ formation in human early embryos 23.99
Transcriptomic analysis of trametinib-resistant HCT116 colorectal carcinoma cells compared to the parental control cells 23.97
RNA-seq in transgenic cells 23.91
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming 23.9
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 23.76
RNA-Seq analysis of breast cancer cells after shikonin treatment 23.73
Transcriptomic profiling of human peripheral blood-derived mast cells 23.71
Genome-wide analyses of chromatin state in human mast cells reveal molecular drivers and mediators of allergic and inflammatory diseases 23.71
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells 23.52
Next generation sequencing analysis of transcriptomes at different timepoints after chlorprothixene treatment in NB4 and Kasumi-1 cells 23.5
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 23.39
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 23.38
mRNA sequencing identifies differential gene expresssion profiles between ASCC3 knock-down cells and control cells 23.36
Searching for target genes of miR-508/509/506/514 in HCT116 cells 23.29
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 23.27
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 23.04
Suppression of the FOXM1 transcriptional program via novel small molecule inhibition 23.03
Transcription differences in DLBCL cell lines U2932, DOHH2 on treatment with TK compound compared to DMSO 22.9
Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation 22.74
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [RNA-Seq] 22.69
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 22.62
RNA-seq of human fibroblasts after irradiation 22.6
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 22.58
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 22.55
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates 22.55
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 22.3
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 22.22
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 22.17
Cell-specific expression and function patterns of microRNA-150-5p in liver fibrogenesis 22.16
Human gut derived-organoids as model to study gluten response and effects of microbiota bioproducts in celiac disease 22.12
RNAseq of HEK293 cells after Chtop knockdown 22.12
Co-transcriptional loading of RNA export factors shapes the human transcriptome 22.12
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 22.09
Profiling of gene expression using RNA-Seq in fibroblasts, iPSCs, iPSC-derived neurons and cells overexpressing Onecut transcription factors 22.07
Changes in chromatin accessibility and gene expression induced by overexpression of ONECUT transcription factors 22.07
Global transcriptional profiling changes upon knockdown of G9a in human non-small cell lung cancer cells 21.83
RNA-seq in untreated and flagellin-treated Human Intestinal Myofibroblast cells (HIMF) 21.8
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived AREG 21.71
KMT2C medaites the estrogen dependence of breast cancer through regulation of ERα enhancer function 21.71
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 21.68
RNA-seq of shEZH2 cells 21.55
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 21.5
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 21.5
Regionally distinct astrocyte interferon signaling promotes blood-brain barrier integrity and limits immunopathology during neurotropic viral infection 21.38
ONECUT2 Drives Neuroendocrine Prostate Cancer Through Hypoxia Signaling 21.34
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 21.31
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 21.31
Global epigenomic reconfiguration during mammalian brain development 21.28
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 21.18
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 21.13
Subclonal cooperation drives metastasis through modulating local and systemic immune microenvironments 21.12
Regulation of hypoxia-inducible factor activity by ZMYND8 21.07
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 21.01
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 20.98
RNA-sequencing time course of Human Intestinal Epithelial Cells (HIECs) following knockdown of miR-30bcd using complementary locked nucleic acids 20.93
Rare cell variability and drug-induced reprogramming as a mode of cancer drug resistance [RNA-seq] 20.84
A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo 20.82
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 20.82
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 20.82
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 20.72
Transcriptomic Profiling of Developing Human Paraxial Mesoderm from 4.5-5 Weeks of Gestation Human Embryos 20.5
A global identification of PUM1 and PUM2 mRNA targets and their protein cofactors in human seminoma TCam-2 cells 20.5
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines [HTS] 20.49
Functional characterization of RNA-binding protein IMP2 in primary Glioma cell lines 20.49
Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors 20.47
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency 20.42
RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS mutant colorectal cancer 20.24
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 20.23
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 20.23
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 20.2
Next-generation sequencing of human dermal fibroblasts transdifferentiated towards the otic lineage 19.95
Reprogramming by de-bookmarking somatic transcriptional program via targeting the BET bromodomains 19.89
PML2-mediated thread-like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome 19.85
PML2‐mediated thread‐like nuclear bodies mark late senescence in Hutchinson–Gilford progeria syndrome [RNA-seq] 19.85
B cells expressing the IgA receptor FcRL4 participate in the autoimmune response in patients with rheumatoid arthritis 19.8
Absence of NKG2D ligands defines human leukaemia stem cells and mediates their immune evasion 19.73
Transcriptome analysis of RANK-positive and RANK-negative luminal progenitor subpopulations in the human breast 19.66
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 19.62
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer 19.62
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer [RNA-seq] 19.62
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity 19.62
FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs 19.61
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 19.56
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 19.51
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of AIM2. 19.38
TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma 19.38
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 19.36
Redifferentiation of expanded human islet β cells by inhibition of ARX 19.34
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 19.28
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma (RNA-Seq) 19.28
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma 19.28
Transcript abundance in A-T-derived iPSC: Comparing isogenic cells to unrelated individual 19.21
An siRNA screen identifies CHD4 as a target for epigenetic therapy 19.19
Genome wide expression change in LCC2 and MCF-7 cells 19.13
RNA-seq Analysis of Castration-Resistant Prostate Cancer With Knock-down of E2F1 19.02
Low-Cell-Number, Single-Tube Amplification (STA) of RNAs Revealed miRNA Changes from Pluripotency to Endothelium 18.99
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing 18.96
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing (RNA-seq) 18.96
RNA sequencing of GLO1-depleted MDA-MB-231 breast cancer cells 18.88
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [MB157_RNA-seq] 18.77
Reversible LSD1 Inhibition with HCI-2509 induces the p53 gene expression signature in high-risk neuroblastoma cells 18.73
Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes 18.72
Expression profiling of ILC transitional populations and Aiolos accessability and H3K27ac histone modifications in transfected MNK3 cells 18.64
RNA-Seq from human ILC transitional populations 18.64
Small molecule targets TMED9, promotes lysosomal degradation to reverse proteinopathy 18.56
Mutant p63 disrupts the key specification switch from the multipotent cell state to stratified epithelia during epithelial differentiation/in ectodermal dysplasia disorders 18.33
Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs 18.32
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier 18.1
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier [human] 18.1
Analysis Of The TGFb-Induced Program In Primary Airway Epithelial Cells Shows Essential Role Of NF-kB/RelA Signaling Network In Type II Epithelial Mesenchymal Transition 18.08
mRNA differential expression analysis in a human ex vivo model of chronic wounds 17.98
Contribution of SRF and Nkx2-5 to androgen-dependent gene expression in prostate cancer 17.94
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 17.86
A High-Throughput Screen Identifies DYRK inhibitor ID-8 that Stimulates Human Kidney Tubular Proliferation 17.82
High-throughput sequencing of the human hepatic progenitor cell niche in PSC and HCV. 17.68
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 17.67
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 17.67
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression and cell death 17.6
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 17.44
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 17.38
Consequences of Ribosomal Protein Haploinsufficiency in Human Hematopoiesis 17.14
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells 17.09
Profiling and bioinformatics analyses reveal differential expression of circular RNA in tongue cancer revealed by high-throughput sequencing 17.05
RNA-seq analysis of uveal melanoma cells treated with FR900359 16.96
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 16.77
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes 16.74
Small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes 16.73
High-throughput RNA sequencing of human preovulatory cumulus and mural granulosa cells (mRNA) 16.73
A novel target of EZH1/2 for treatment of mantle cell lymphoma 16.69
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 16.64
6mer seed toxicity in tumour suppressive microRNAs 16.51
Tafazzin Regulates Cell State by Modulating Phosphatidylethanolamine and Phosphatidylserine levels 16.51
Expression data for hiPSC-derived RPE treated with 10mM Nicotinamide or vehicle 16.49
mRNA sequencing of the mouse and human Hep-Orgs, Chol-Orgs and primary hepatocytes 16.28
Next Generation Sequencing Facilitates Quantitative Analysis of Human Primary and Pluripotent Stem Cell-Derived Epicardial Cell Transcriptomes 16.28
Human cell line and subcutaneous tumor 16.14
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 16.05
Proximity-CLIP provides a snapshot of occupied cis-acting elements on RNA in different subcellular compartments on a transcriptome-wide scale 16.02
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 15.85
HDAC and NFκB antagonists synergistically inhibit growth and metastatic dissemination of MYC-driven medulloblastoma 15.81
RNA-sequencing in immortalized human mammary epithelial cells 15.64
Alternative splicing regulated by QKI and RBFOX1 promotes the mesenchymal cell state in breast cancer 15.64
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 15.5
Integration of genome-wide DNA methylome and transcriptome of human intestinal fibroblasts reveals novel candidate gene signatures in Crohn’s disease-associated fibrosis 15.4
Methylome, hydroxymethylome, and integrative transcriptome profiling in human CRC tissue and paired normal tissues 15.38
Gene expression analysis in U251 and U87 cells transduced with NANEP5 vector. 15.22
ARID1A and ARID1B loss in HCT116 and TOV21G cells 15.22
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 15.16
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 15.02
The transcriptomic landscape of MAIT cell development in the thymus (NN41 RNAseq data set) 14.98
Fbxo32 mediated gene expression program underlies EMT and metastasis 14.91
Trans-differentiation of human adult peripheral blood T cells into neurons 14.6
Effect of Hotair overexpression in human breast cancer cell lines 14.49
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 14.49
Human Airway Smooth Muscle Transcriptome Changes in Response to Asthma Medications 14.18
Transcriptomic changes mediated by β-amyloid in human aortic endothelial cells (HAOEC) 14.11
Radiomic and gEnomic approaches for the enhanced DIagnosis of REnal Cancer (REDIRECt): A translational pilot study 13.68
ARID1A regulates condensin II distribution and chromosomal partition 13.64
ARID1A regulates condensin II distribution and chromosomal partition [RNA-seq] 13.64
RNASeq of Healthy Human Skin Tregs and CD4 Teffs versus Psoriatic Human Skin Tregs and CD4 Teffs 13.54
A pooled single-cell genetic screen identifies regulatory barriers in the continuum of the epithelial-to-mesenchymal transition 13.52
Integrative analysis of mRNA and lncRNA profiles identified pathogenetic lncRNAs in esophageal squamous cell carcinoma 13.25
RNA expression analysis upon JMJD1C depletion 13.14
JMJD1C is required for the survival of acute myeloid leukemia by functioning as a co-activator for key transcription factors 13.14
Similarity of therapeutic networks induced by a multi-component herbal remedy in neurovascular unit cells 13.1
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 12.88
RNA-seq and Hi-C sequencing of neutrophil-like cells migrated through large or small pores 12.78
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [RNA-seq] 12.78
Next Generation Sequencing Facilitates Quantitative Analysis of colorectal cancer cells transfected with NC siRNA or RPL9 siRNA 12.74
RNA sequencing of human mammary epithelial cells 12.53
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 12.45
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 12.45
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program 12.41
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program (RNA-Seq) 12.41
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 12.37
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 12.37
Transcription factors OVOL1 and OVOL2 induce the mesenchymal to epithelial transition in human cancer 12.26
Cooperation of GRSF1 and the mitochondrial degradosome (hSuv3-PNPase complex) in degradation of mitochondrial RNA 12.1
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 12.03
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells [RNA-seq] 11.76
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells 11.76
Identifying a novel candidate diagnostic and prognostic biomarker SPRR3 for oral squamous cell carcinoma via mRNA Sequencing and Bioinformatics 11.61
Identification of differential expressed genes of JQ1 or JQ1+Bortezomib in colorectal cancer cells 11.5
Immune Checkpoint Regulation of Pulmonary Fibrosis [bulk RNA-seq] 11.45
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 11.31
A Unique Epigenomic Landscape Defines Human Erythropoiesis 11.24
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 11.24
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 11.12
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 11.07
Single cell RNA-seq resolves lineage-specific activation dynamics of human blood and tissue T cells 11.05
PRDM1 inhibits proliferation of human colon cancer organoids 10.89
Mesothelioma xenografts in nude mice: PBS treated versus pirfenidone treated 10.7
Specific inhibition of DPY30 activity by peptides suppresses blood cancer cell growth 10.68
RNA-seq analysis of primary patient samples to characterize the CNS leukemia 10.59
Transcriptome analysis of CNS leukemia 10.59
ELP1 splicing correction reverses proprioceptive sensory loss in familial dysautonomia 10.51
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 [RNA-Seq] 10.19
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 10.19
CD73 knockdown effect in pancreatic cancer cell lines 10.07
FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST) 9.86
Expression profile of GIST48 cells with siETV1 or siFOXF1 knockdown 9.86
The NFkB subunit RELA is a master transcriptional regulator of the committed epithelial-mesenchymal transition in airway epithelial cells 9.71
Nucleoporin-mediated regulation of cell identity genes 9.66
BET bromodomain inhibition 9.65
Effect of BET bromodomain inhibition with JQ1 in stressed human derived iPS cardiomyocytes 9.65
Gene expression signatures of innate lymphoid cells from human blood 9.6
Gene expression profiles of tumor-infiltrating CD8 T cells in hepatocellular carcinoma 9.49
Efficient derivation of microglia-like cells from human pluripotent stem cells 9.46
Comparative Analysis of Cas9 Activators Across Multiple Species 9.37
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 9.37
Transcriptome analyses of human pancreatic islets and pseudoislets 9.33
Differential gene expression in Jagged1 treated human dental pulp cells. 9.23
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 9.23
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 9.23
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 9.18
Ribosome profiling of TGFb-treated cells indicates reduced leucine availability 9.1
Gene expression profiling of KSHV-infected periodontal ligament cells 9.07
The Developmental Heterogeneity of Human Natural Killer Cells Defined by Single-cell Transcriptome 8.5
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 8.42
A single cell reference map for human blood and tissue T cell activation 8.2
Metastasis in triple-negative breast cancer 8.0
Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer. 8.0
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 7.99
Early transcriptome profiling of microRNA-mediated neuronal reprogramming [RNA-seq timecourse] 7.96
MiR-26 dampens IL-6 production by down-regulating TNF-a/NF-kB signaling through silencing HMGA1 and MALT1 and not by directly targeting IL-6 mRNA 7.66
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 7.61
RNA-seq analysis of the role of HBO1 (KAT7/MYST2) in the ovarian cancer cell line UWB1.289. 7.6
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5’ and 3’ Ends of Genes 7.14
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 7.02
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 6.9
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 6.9
Identification of renal resident macrophages across species [C1] 6.81
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 6.77
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 6.77
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 6.68
Transcriptome Analysis and Functional Identification of Adipose-Derived Mesenchymal Stem Cells in Secondary Lymphedema 6.6
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 6.53
Transcriptome profiling of microRNA-mediated neuronal reprogramming with REST repression at day 7 6.51
Cooperative and Antagonistic Transcriptional Regulation by BRG/BRM [RNA-seq] 6.51
Co-regulation of transcription by BRG1 and Brm, two mutually exclusive SWI/SNF ATPase subunits 6.51
Genes altered in expression by Cisplatin treatment in lung cancer cell lines 6.4
Heterogeneous effects of massive hypoxia pathway activation in kidney cancer 6.39
Genome Wide Chromatin Mapping of accessibility (ATAC-seq) and H3K27ac histone modifications in CD56bright and CD56dim natural killer cells 6.22
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 6.15
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 6.08
Gene expression analysis of a panel of human fibroblasts that generate an aligned (anisotropic) vs non-aligned extracellular matrix 6.03
ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression 5.59
Profiling gene expression changes in ovarian cancer cells seeded on 3D organotypic culture of omentum 5.57
Gene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4 5.55
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 5.53
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 5.51
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 5.48
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 5.48
Specific labeling of stem cell activity in human colorectal organoids using an ASCL2-responsive minigene 5.46
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 5.36
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 5.08
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 5.07
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 5.07
Regulators of cellular heterogeneity in basal-like breast cancer influence symmetric versus asymmetric division rates (shRNA targeting) 4.93
Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells 4.92
RNA sequencing of Formalin-Fixed, Paraffin-Embedded Specimens for Gene Expression Quantification and Data Mining 4.79
RNA-seq analysis upon ARID1B overexpression 4.78
Integrating the Epigenome to Identify Novel Drivers of Hepatocellular Carcinoma 4.75
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 4.38
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 4.38
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 4.32
Transcriptome of human ILC2s; primary vs IL-1b-primed 4.12
A single-cell transcriptome atlas of the human pancreas 3.86
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  3.76
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 3.69
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 3.69
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 3.53
Urinary sediment transcriptomic and longitudinal data to investigate renal function decline in type 1 diabetes 3.51
Transcriptional profiling at the DLK1/MEG3 domain explains clinical overlap between imprinting disorders 3.5
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 3.27
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 3.27
Effects of plasticizers (bisphenol A, bisphenol AF) and an herbicide in MCF7 human breast cancer cells 3.25
Genome-wide maps of transcriptomic and epigenomic state in melanoma cell lines 3.06
BMS-470539 on human synovial fibroblasts 2.98
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 2.86
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 & MCM7 2.85
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 2.79
Reprogramming of dermal papilla cell intact gene signature with 3D culture and Lef-1 overexpression 2.69
Transcriptomic profiling of sequential tumours from breast cancer patients provides a global view of metastatic expression changes following endocrine therapy 2.64
Truncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line 2.59
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 2.53
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 2.35
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression 2.06
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression [RNA-Seq] 2.06
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 1.98
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 1.98
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 1.76
Transcriptome Profiling Reveals the key genes and pathways involved in polycystic ovary syndrome [RNA-seq] 1.72
Identification of epigenetic interactions between miRNA and DNA methylation associated with polycystic ovarian syndrome 1.72
Gene expression profiles of PD1-high, PD1-intermediate, and PD1-negative tumor-infiltrating CD8 T cells in hepatocellular carcinoma 1.43
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 1.36
Does osteogenic potential of clonal human bone marrow mesenchymal stem/stromal cells correlate with their vascular supportive ability? 1.36
Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and Natural Killer Cell Function 1.27
Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy 0.86
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 0.72
RNA-Seq identifies condition-specific biological signatures of ischemia-reperfusion injury in the human kidney 0.71
Transcriptome profiling of de-differentiated chondrocytes over-expressing miR-138 or miR-181ab1 during osteogenic induction 0.67
RNA expression profiles comparing primary and omental ovarian carcinoma samples 0.49
The transcriptome of human endometrial mesenchymal stem cells under TGFβR inhibition reveals improved potential for cell-based therapies 0.48
Functional Cardiac Fibroblasts Derived from Human Pluripotent Stem Cells via Second Heart Field Progenitors 0.45
Transcriptomic analysis of the role of the integrin a6b4 in detached cells 0.35
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 0.17
Comparison of microRNA Profiling Platforms 0.1
Comparison of microRNA Profiling Platforms (HTS) 0.1
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 0.07


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