Gene Query: SPG7

Dataset Description Geneva Score
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program (RNA-Seq) 40.8
RUNX1 mutations lead to a myeloid differentiation block by altering the RUNX1 transcriptional program 40.8
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 39.14
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 39.14
Comprehensive comparative analysis of 5’ end RNA sequencing methods 39.03
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 31.4
Studying the selectivity of a targeted small molecule degrading a hypoxia-associated non-coding RNA 28.5
Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases 27.41
WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription 20.47
Function of HNRNPC in breast cancer cells by controlling the dsRNA-induced interferon response 17.7
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 17.67
Single-cell transcriptome of human epithelial cells reveals novel insights into early innate immune responses to influenza virus and viral antagonism 17.44
Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues 16.83
Disruption of the exocyst induces podocyte loss and dysfunction 16.49
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 16.46
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 16.32
Next generation sequencing of small RNAs isolated from exosomes in human semen 16.3
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 15.92
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 15.85
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 15.31
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 14.55
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 14.1
RNA expression following TMPRSS11B overexpression or depletion 13.86
MULTI-seq: Universal sample multiplexing for single-cell RNA sequencing using lipid-tagged indices 13.78
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation 13.77
Argonaute proteins couple chromatin silencing to alternative splicing 13.73
Argonaute proteins couple chromatin silencing to alternative splicing (RNA IP-Seq) 13.73
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 13.67
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 13.66
NRDE2 negatively regulates nuclear exosome functions 13.5
Club cells surviving influenza A virus infection induce temporary non-specific anti-viral immunity 13.37
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 13.26
Integrating single-cell transcriptomic data across different conditions, technologies, and species 12.92
The m 6 A-methylase complex recruits TREX and regulates mRNA export. 12.36
RNA-seq in HT-29 colorectal cancer cells after F. nucleatum treatment 12.08
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 11.96
The effect of REST and its alternatively spliced transcript, REST-003, on breast cancer invasiveness 11.72
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 11.62
Evidence for HOXC6 as a potential molecular marker for non-small cell lung cancer 11.55
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 11.41
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 11.41
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 11.37
SIX4 acts as a master regulator of genes associated with the malignant phenotype of non-small cell lung cancer cells 11.17
Sensing self and nonself circular RNAs 11.08
A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo 10.99
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 10.96
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 10.92
Genome wide mapping of polyadenylation sites in proliferating and contact-inhibited cells and cells with knockdown of cleavage and polyadenylation factors 10.9
Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic β-cell death 10.85
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 10.3
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression [RNA-Seq] 10.13
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression 10.13
Exploring the RNA landscape of endothelial exosomes 9.78
Triple vectors expand AAV transfer capacity in the retina 9.77
Major roles of cyclobutane pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation 9.75
TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality 9.75
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation 9.7
Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing analysis 9.65
RNA polymerase in pre-B-ALL cell lines 9.63
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 9.53
Identification of ZEB1-regulated gene expression changes in HCC827 human lung adenocarcinoma cells 9.39
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 9.25
Effect of the knockdown of MLL1 and MLL2 on pediatric high grade glioma 9.24
Indoxyl sulfate stimulates angiogenesis by regulating reactive oxygen species production via CYP1B1 9.22
Identification of Atrial Fibrillation associated genes and functional non-coding variants 9.07
Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig 8.95
NET-CAGE Characterizes the Dynamics and Topology of Human Transcribed Cis-regulatory Elements 8.82
Effect of hypoxia and TGFβ1 on gene expression in HPF fibroblast cells 8.8
Human iPSC-based Modeling of Late-Onset Disease using Progerin-induced Aging 8.77
Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle by inducing capillary sprouting and decreasing vascular permeability via reduced eNOS activity 8.65
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 8.58
Targeted enhancer activation by a subunit of the integrator complex 8.58
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 8.52
Transcriptomic analysis of human tonsillar TFH subsets 8.49
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 8.46
RNA-Seq of human induced pluripotent stem cell-derived cardiomyocytes from a cardiomyopathy patient and familial control 8.45
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 8.43
RNA-sequencing of formalin fixed human primary melanoma tissue 8.4
Real-time observation of light-controlled transcription in living cells 8.4
Gene expression in PANC1 cells treated with Rakicidin 8.39
Expression data from human perivascular stem cell-derived extracellular vesicles (PSC-EVs) and PSCs 8.36
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 8.36
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 8.35
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 8.35
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells 8.31
CD95/Fas ligand mRNA is toxic to cells 8.21
Characterization of the Merkel cell carcinoma miRNome 8.2
RNA expression analysis of neuroblastoma cell lines treated with epigenetic drugs 8.13
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 8.1
Regulartory effect of HNRNPL and LARP on RNA expression in LNCaP prostate cancer cells 8.02
HNRNPL and its RNA Targets in Prostate Cancer 8.02
Dynamic epigenetic remodeling underlies microRNA-mediated transdifferentiation of human adult fibroblasts into neuronal subtypes 8.01
RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures 7.95
RNA-Seq analysis of human lung fibroblasts exposed to TGF-β 7.85
The DNM3OS lncRNA is a reservoir of fibromiRs with major functions in fibroblast response to TGF-beta and fibrogenesis 7.85
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 7.68
Identification of microRNA-668 and microRNA-489 targets by RISC immunoprecipitation 7.64
Single-cell analysis of human kidney organoids 7.62
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 7.62
RNA-seq analysis to identify the genes regulated by p53-SET interplay 7.57
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 7.56
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development [set 1] 7.54
Quantitative Analysis of negative control and overexpression-TRIB1 in PC3 and DU145 Transcriptomes 7.49
HIV-1 perturbs homeostatic ILCs, unmasks ILC1 plasticity, and boosts TCF7+ memory NK cells 7.48
mRNA expression in iPS cells generated by a synthetic self-replicative RNA 7.29
Functional interactions between Mi-2β and AP1 complexes control response and recovery from barrier disruption 7.27
Defining a microRNA-mRNA targetome for calcineurin inhibitor induced nephrotoxicity 7.25
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 7.22
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 7.21
ETV7 and interferon response 7.21
Impact of DNA MMR activity on antiviral gene expression in H441 cells infected with influenza A virus 7.18
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 7.1
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 7.06
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 7.06
A global identification of PUM1 and PUM2 mRNA targets and their protein cofactors in human seminoma TCam-2 cells 6.97
HNF1A deficiency impairs β-cell fate, granule maturation and function 6.96
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 6.95
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples 6.83
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 6.83
Transcriptome analysis reveals differential splicing events in IPF lung tissue 6.8
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures 6.79
High-resolution liver cancer genomic profiling links etiology, epigenetic and mutation signatures [RNA-Seq] 6.79
SnapShot-Seq: a method for extracting genome-wide, in vivo mRNA dynamics from a single total RNA sample 6.66
Landscape and variation of RNA secondary structure across the human transcriptome 6.64
Flura-seq identifies organ-specific adaptations in metastasis-initiating cells 6.63
Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV. 6.61
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [K562] 6.6
RNAseq of HEK293 cells after Chtop knockdown 6.56
Co-transcriptional loading of RNA export factors shapes the human transcriptome 6.56
Tracking distinct RNA populations using efficient and reversible covalent chemistry 6.55
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma 6.54
IL-6/Stat3-Dependent Induction of Distinct, Obesity-Associated Natural Killer Cells Deteriorates Energy and Glucose Homeostasis 6.52
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 6.49
U1 snRNP telescripting regulates size-function stratified human genome 6.48
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 6.47
The evolution of N6-methyladenosine in primates 6.46
RNA-Seq analysis of human Tr1, Tregs and IL10neg cells 6.45
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 6.45
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 6.45
Discovery of cis-spliced chimeric RNAs between adjacent genes in human prostate cells 6.44
Transcriptomic insights into human decidual and peripheral blood CD4 T cells 6.42
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) of BJ cells treated with Nutlin-3a, an MDM2 inhibitor, which induces p53. 6.33
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming 6.32
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype [RNA-Seq] 6.31
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype 6.31
NOTCH signaling is activated in and contributes to resistance in enzalutamide-resistant prostate cancer cells 6.31
Cleavage Factor Im as a key regulator of 3’ UTR length 6.28
Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells 6.26
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 6.25
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 6.25
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 6.25
Epigenomes and transcriptomes of human monocytes before and after in vivo exposure to Bacillus Calmette-Guérin vaccine 6.22
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 6.22
m6A-dependent regulation of messenger RNA stability 6.21
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 6.19
Effect of CHKA knockdown on C4-2 cell transcriptome 6.19
RNA-seq of tumor cells following angiopellosis extravasation 6.19
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice 6.18
Regulation of protein translation during mitosis 6.16
RNA-seq melanoma 6.15
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 6.14
DNA Methylation Reprograms Metabolic Gene Expression in End-Stage Human Heart Failure 6.13
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 6.13
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA) 6.12
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 6.12
Transcriptome analysis in Neobractatin treated cells 6.11
Paxillin regulates genomic networks in prostate cancer [PC3] 6.1
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 6.08
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration 6.08
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [mutant MEF2C] 6.07
Role of XRN2 ribonucleolytic activity in RNA metabolism 6.07
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 6.01
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 6.0
Hierarchy of mono- and bi-allelic TP53 alterations in Multiple Myeloma cell fitness 5.96
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 5.95
H3K27Ac in MCF7 Y537S ER mutant cells and RNAseq with and without treatment with THZ1 5.94
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 5.92
Noncoding regions are the main source of targetable tumor-specific antigens 5.91
Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells 5.9
Differential expression of long non‑coding RNA and mRNA in children with Henoch‑Schönlein purpura nephritis 5.88
RNA-seq of YB5 cells treated with Proscillaridin A 5.87
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 5.86
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 5.86
Intrahepatic MAIT cell gene expression revealed by RNA-seq 5.85
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 5.74
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (chromatin-bound RNA-seq) 5.73
Diarrhoeal mechanisms of the Campylobacter jejuni enteritis 5.72
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 5.71
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros 5.69
Tyrosine Kinase Inhibitor Cardiotoxicity 5.67
High-Throughput Screening of Human Induced Pluripotent Stem Cell Cardiomyocytes Predicts Tyrosine Kinase Inhibitor Cardiotoxicity 5.67
Molecular Mechanisms of Endothelial Hyperpermeability 5.67
Transcriptomic profiling of O-GlcNAcylated mRNA-protein complexes by using OG-CLAP in HeLa cells. 5.66
RNA-seq of Single-Cell Genotyping of Transcriptomes 5.65
Single-Cell Genotyping of Transcriptomes 5.65
Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates 5.49
Diverse and Targetable Kinase Alterations Drive Histiocytic Neoplasms 5.48
Whole transcriptome sequencing identifies increased CXCR2 expression in PNH granulocytes 5.48
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ 10x genomics] 5.46
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 5.44
Identification of a unique subtype of lung squamous cell carcinoma defined by SOX2 and a neural differentiation factor BRN2 [RNA-seq] 5.44
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue 5.38
Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells 5.38
Transcriptome analysis in a radiosensitive and a radioresistant cell line after ionizing radiation 5.37
Evaluating pre-clinical models for studying NASH driven HCC. 5.29
Functional Importance of eRNAs for Estrogen-dependent Gene Transcriptional Activation 5.27
Effect of SHP2 inhibition on hepatic stellate cell transcriptome. 5.24
Transcriptome of TNF-a-treated and untreated HeLa cells before and after TFIIB knockdown 5.22
Replication defective viral products exploit a cellular pro-survival mechanism to establish persistent infections 5.17
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 5.15
POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells 5.14
Identification of epigenetic interactions between miRNA and DNA methylation associated with polycystic ovarian syndrome 5.13
Transcriptome Profiling Reveals the key genes and pathways involved in polycystic ovary syndrome [RNA-seq] 5.13
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 5.13
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 5.11
Identification of transcription start sites for human A549 cell line using ReCappable-seq 5.06
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination 5.01
RNA sequencing of Formalin-Fixed, Paraffin-Embedded Specimens for Gene Expression Quantification and Data Mining 4.97
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells 4.96
Patterned human microvascular grafts enable rapid vascularization and increase perfusion in infarcted hearts 4.96
Capturing the Interactome of Newly Transcribed RNA (RICK) 4.95
Capturing the Interactome of Newly Transcribed RNA 4.95
Transcriptional profiling of LS1034 cells treated with tepoxalin 4.95
Gene expression analysis upon mtDNA depletion 4.93
Gene expression analysis upon mtDNA depletion [RNA-seq] 4.93
Fibroblasts in cholesteatoma activate osteoclasts. 4.92
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 4.91
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 4.89
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 4.86
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 4.79
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 4.78
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 4.78
TGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity 4.76
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 4.73
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 4.73
Intrinsic histone acetyltransferase activity of BRD4 is responsible for nucleosome eviction and transcriptional activation 4.73
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 4.67
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 4.67
HeLa transcriptome induction by IFN gamma and indoleamine 2,3-dioxygenase (IDO) 4.63
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 4.61
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation 4.59
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation (RNA-Seq) 4.59
Transcriptome-wide profiling of poly(A)-tail length, translation efficiency and mRNA stability using TED-seq, mRNA-seq, Ribo-seq and PRO-seq in ER stress conditions 4.58
Illumina Total RNA-seq in HeLa 4.57
RNA-seq of PC3 prostate cancer cell line xenografts in mice administered the ghrelin receptor antagonist [D-Lys3]-GHRP-6 or PBS for two weeks 4.55
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 4.51
In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity 4.47
Total RNA-seq in ALL-SIL upon JQ1 inhibition 4.46
Dynamic 3D chromosomal landscapes in acute leukemia 4.44
Dynamic 3D chromosomal landscapes in acute leukemia [RNA-Seq] 4.44
Impact of flanking chromosomal sequences on localization and silencing by the ncRNA XIST 4.43
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (RNA-Seq) 4.37
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma 4.37
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors 4.35
CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells 4.31
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 4.3
Transcriptome of activated human and mouse MAIT cells 4.26
Genome-wide CRISPR-Cas9 screen identifies SLC1A3 as a key contributor to L-asparaginase Resistance in Solid tumors 4.25
Subclonal cooperation drives metastasis through modulating local and systemic immune microenvironments 4.24
Bioreactor-engineered cancer tissues mimic phenotypes, gene expression profiles and drug resistance mechanisms detectable in xenografts and clinical specimens. 4.23
Effect of MDK expressing Melanoma cells conditioned media in Human LEC 4.22
Studying the selectivity of a small molecule Synucleozid on transcriptome 4.21
Global gene expression profile of dasatinib-resistant RCH-ACV cells 4.2
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells 4.17
Iron response of HepG2 cells 4.17
Multiple roles for Grainyheadlike transcription factors in the establishment and maintenance of human mucociliary airway epithelium 4.16
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 4.15
p63 controls the enhancer landscape during keratinocyte differentiation 4.15
Differential gene expression by suppression of either SOX2 or TP63 in KYSE70 human esophageal squamous carcinoma cell line. 4.13
Low-Cell-Number, Single-Tube Amplification (STA) of RNAs Revealed miRNA Changes from Pluripotency to Endothelium 4.05
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 4.05
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 4.02
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 3.95
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 3.95
Genome-wide RNA-sequencing (RNA-seq) of benign and malignant prostate cell lines without and with androgen (R1881) stimulation. 3.92
RNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation 3.91
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 3.9
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth [RNA-Seq] 3.87
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth 3.87
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 3.76
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 3.76
Transcriptome landscape of human primary monocytes response upon different ligand glucocorticoids 3.76
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 3.75
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 3.74
Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity 3.73
Differential responses of human fetal brain neural stem cells to Zika virus infection 3.7
Functional Inflammatory Profiles Distinguish Myelin-Reactive T Cells from Patients with Multiple Sclerosis 3.68
Tracing Enhancer Networks using Epigenetic Traits (TENET) 3.68
A bioinformatics approach reveals novel mechanisms of the OVOL transcription factors in the regulation of epithelial-mesenchymal cell programming and cancer progression. 3.67
FUS mutant human motoneurons transcriptome analysis reveals altered pathways and impairment of microRNA function 3.66
X-Ray induced DNA-Hydroxymethylation changes 3.64
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 3.63
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 3.63
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells [RNA-seq] 3.6
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells 3.6
Quantitative Proteomics Reveals a Unique Wiring of Signaling Pathways that Protects Human Regulatory T Cell Identity 3.57
BET bromodomain inhibition 3.47
Effect of BET bromodomain inhibition with JQ1 in stressed human derived iPS cardiomyocytes 3.47
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 3.43
ZNF599 and DNMT3A coordinately control nuclear envelope organization by repression of SUN4 expression 3.42
Transcriptome landscape of HeLa response upon triamcinolone acetonide 3.41
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 3.38
Ectoderm specification of H1 human embryonic stem cells 3.38
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 3.37
Peptidomimetic blockade of MYB in acute myeloid leukemia 3.37
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 3.37
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 3.34
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes 3.32
Multi-omic measurements of heterogeneity in HeLa cells across laboratories 3.3
RNA sequencing of CACO-2 cells incubated with bifidobacteria grown on human milk oligosaccharides. 3.28
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation II 3.28
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 [RNA-Seq] 3.25
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 3.25
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 3.19
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 3.19
Identification of renal resident macrophages across species 3.19
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5’ and 3’ Ends of Genes 3.19
RNA-Seq profiling in PBMCs and spinal cord from ALS patients and healthy controls 3.18
Comprehensive RNA-Seq profiling in PBMCs of ALS patients and healthy controls 3.18
Loss of EGFR-DDEF1 signaling in metastatic and unresectable hepatoblastoma 3.16
quanTIseq: quantifying immune contexture of human tumors 3.11
Single Cell RNASeq profiling of stromal vascular fraction from Subcutaneous and visceral adipose tissue 3.1
RNA-Sequencing of human dermal lymphatic endothelial cells (HDLEC) treated with siRNA targeting YAP/TAZ and YAP5SA 3.06
Sequencing of freshly produced RNA following exposure of cells to DNA damage-inducing UV mimetic 4-hydroxyaminoquinolone (4-NQO) 3.03
Identification of miRNA signatures during the differentiation of hESCs into retinal pigment epithelial cells 3.02
Comparative gene expression profiling of human primary endotheliocytes cultivated on polyurethane-based electrospun 3D matrices and natural decellularized vein 2.99
Genome-wide analysis of the Integrator complex 2.98
Genome-wide analysis of the Integrator complex (HTS) 2.98
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 2.92
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 2.9
Evaluation of the effectiveness of semen collection and sperm purification methods for spermatozoa transcript profiling 2.89
Discovering human diabetes-risk gene function with genetics and physiological assays 2.86
Total RNA-seq in ALL-SIL upon TLX1 knockdown 2.83
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff 2.83
Identification of renal resident macrophages across species [C1] 2.78
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 2.74
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 2.7
Gene expression profile in breast cancer cells 2.7
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 2.69
Metastasis in triple-negative breast cancer 2.62
Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer. 2.62
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 2.6
Age-Related Gene Expression Changes in Prostate Cancer Patients [RNA-Seq] 2.53
Age-Related Gene Expression Changes in Prostate Cancer Patients 2.53
RNA-seq and small RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 2.46
RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 2.46
mRNA recovered upon RNF219 IP. [RNA-IP] 2.46
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability 2.45
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability [RNA-seq] 2.45
Diarrhea in lymphocytic colitis: ERK1/2-dependent ENaC dysregulation and claudin-4-, -5- and -8-related barrier defects 2.41
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 2.39
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 2.39
A novel target of EZH1/2 for treatment of mantle cell lymphoma 2.36
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 2.31
RNA profiling Analysis of the Serum Exosomes Derived from Active and Latent M.tuberculosis infectious Patients 2.29
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO] 2.27
MARS Seq data from human cortical organoids 2.24
Low carbohydrate diet study for non-alcoholic fatty liver disease patients 2.24
RNA Seq of Alagille liver biopsies 2.16
Alagille_Nodder 2.16
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 2.16
Gene expression profiling in metabolically heterogeneous human lung tumors 2.16
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 2.13
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 2.11
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid [TEMRA] 2.11
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid 2.11
Identification of the RB loss-induced transcriptome in prostate cancer [RNA] 2.1
Identification of the RB loss-induced transcriptome and E2F1 cistrome in prostate cancer 2.1
Expression profiling of MCF-7 cells with 10nM treatment of TCDD 2.03
Expression profiling of MCF-7 cells with treatment of TCDD 2.03
Profiling of lung tumor-infiltrating CD8 T cells according to their expression status of CD39 1.98
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 1.97
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 1.94
RNA-seq of primary patient AML samples 1.92
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [RNA-seq] 1.84
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 1.78
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 1.78
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 1.75
The mRNA export receptor NXF1 coordinates transcriptional dynamics, alternative polyadenylation and mRNA export 1.74
Transcriptome analysis of fetal Klinefelter testis tissue samples compared to controls 1.72
Analysis of active enhancers and direct androgen receptor target genes in VCaP prostate cancer cells 1.71
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 1.71
SNHG5 siRNA knock down in HCT116 cells 1.71
Aortic Valve Tissue: Stenosis vs. Sclerosis 1.64
Kidney compartment specific eQTL studies highlight causal genes and pathways for renal disease development 1.64
RNA expression profiles from HUVECs overexpressing adenovirally delivered HIF1a and HIF2a proteins 1.61
RNA-seq, ChIP-seq and single cell RNA-seq of human skin Langerhans cells 1.6
Dilated cardiomyopathy vs Myocarditis 1.59
RNA-sequencing 1.59
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 1.55
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 1.54
A practical evaluation of alignment algorithms for RNA variant calling analysis 1.54
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes 1.52
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes [RNA-seq] 1.52
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis 1.51
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [RNA-Seq_Hs] 1.51
A single-cell transcriptome atlas of the human pancreas 1.48
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells [RNA-Seq] 1.45
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells 1.45
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 1.45
Interaction between mitoNEET and NAF-1 in cancer cells 1.45
Integration of ATAC-seq and RNA-seq Identifies Human Alpha Cell and Beta Cell Signature Genes 1.43
transcriptome studies of BRD4 inhibitor BDF-1253 on renal clear carcinoma 786-O cells 1.43
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 1.4
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 1.33
Effect of nuclear IL-33 on gene expression 1.32
Dual RNA-seq – High-resolution comparative Dual RNA-seq time-course 1.3
Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains 1.3
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 1.29
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.27
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 1.26
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 1.25
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 1.25
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 1.24
CRISPR-Cas9 based screen for p53-bound enhancers that function in oncogene-induced senescence 1.22
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 1.22
Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity 1.19
KAP1 regulates ERVs in differentiated human cells and contributes to innate immune control 1.18
Recovery and analysis of nascent RNA 1.17
The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains 1.17
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 1.15
The control of rRNA synthesis during the directed differentiation of human embryonic stem cells precedes heterochromatin formation. 1.15
RNA-seq characterization of downstream effects of upregulating SMN2 via down-regulating PRC2 or blocking the PRC2:SMN-AS1 interaction with a mixmer oligonucleotide 1.11
Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and Natural Killer Cell Function 1.07
Browning of human adipocytes requires KLF11 and reprogramming of PPARγ super-enhancers 1.06
Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer 1.06
RNA seq_PDX2_SHP099 1.06
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 1.04
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 1.02
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 0.93
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 0.92
RNA-seq differential expression studies: more sequence, or more replication? 0.92
Effect of BB608 on Gene Expression in HNSCC Cell Line 0.88
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells 0.86
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells [GRO-seq] 0.86
Transcriptome analysis of CD8+ T cells from healthy controls and patients wth CD46 deficiency 0.85
Analysis of transcriptomes of healthy donor and CD46 deficient CD8 T cells 0.85
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.81
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 0.79
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 0.73
FOXO1 is an oncogenic mediator in AML1-ETO leukemia 0.73
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 0.7
Deep RNA sequencing of the human placental transcriptome 0.7
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 0.68
Human pulmonary artery endothelial cells (hPAECs) with downregulated BMPR2 signaling demonstrate a unique gene expression signature after exposure to overexpression of AdAlox5 0.68
UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation 0.68
RNA sequencing of GLO1-depleted MDA-MB-231 breast cancer cells 0.66
Integration of kinase and calcium signaling at the level of chromatin underlines inducible gene activation in T cells 0.66
The transcriptome of Kawasaki Disease arteritis 0.66
Vammin induces a highly efficient angiogenic response through VEGFR-2/NRP-1 and bypasses the regulatory function of VEGFR-1 0.65
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. 0.65
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. [RNA-Seq] 0.65
Molecular Hallmarks of Experimentally Acquired Immunity to Malaria [Pilot Study] 0.64
Pro-angiogenic Ginsenoside F1 and Rh1 Inhibit Vascular Leakage by Modulating NR4A1 0.64
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 0.62
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 0.61
A20 regulates canonical wnt-signaling through an interaction with RIPK4 0.6
miRNAs affected by antagomiR-17 treatment 0.58
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 0.58
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq] 0.57
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine 0.57
HEK293 Heat-shock experiment 0.56
Functional significance of the HIV-1 Tat signature amino acid residues 0.55
Global transcriptomic analyses of bronchial epithelial cells exposed to 5 ng/mL TGF-β1 and 10 nM Estrogen individually and in combination 0.55
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 0.52
Changes in CD34 and Erythroid Progenitor Transcriptome After RUNX3 Kock-down 0.51
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 0.49
Critical role for Lymphocytes in Producing FLT3LG in Tumors and Driving Checkpoint Therapy-Receptive Immune Microenvironments 0.48
Energy Metabolism during Anchorage-Independence 0.47
Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq 0.46
RNA sequencing of prostate cancer and normal tissue from African Americans and European Americans 0.46
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 0.44
ERK signaling regulates opposing functions of JUN family transcription factors in prostate cancer cell migration 0.44
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 0.44
The ARID1A tumor suppressor controls global transcription via pausing of RNA Polymerase II 0.43
m6A/m-Seq of human B-lymphocyte cell lines from healthy controls and major depressive disorder patients 0.41
The role of m6A/m-RNA methylation in stress response regulation 0.41
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML [RNA-Seq human] 0.4
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML 0.4
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 & MCM7 0.4
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 0.38
Gene expression profiles of PD1-high, PD1-intermediate, and PD1-negative tumor-infiltrating CD8 T cells in hepatocellular carcinoma 0.36
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency 0.31
Expression profile of MM.1S tumors folloiwing treatment with bortezomib 0.3
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 0.25
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia 0.23
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.23
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.23
Suppression of NAF-1 in Breast Cancer Cells Reduces their Tumorigenicity by Interfering with Cellular Iron Distribution and Metabolism and Ensuing ROS Formation and Apoptosis 0.21
RNA-seq of HUVEC ± shRNA knockdown of SENCR 0.21
Human ES Cell-derived Hepatoblasts are an Optimal Lineage Stage for HCV Infection 0.19
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 0.13
The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells 0.13
Screening in Human Cardiac Organoids Identifies a Requirement for the Mevalonate Pathway in Cardiomyocyte Proliferation 0.11
Transcriptomes of human monocytes from patients with familial hypercholesterolemia before and after statin treatment 0.1
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 0.09
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 0.06
RNA-seq after siRNA targeting DDX24 applied to iHUVECs cell lines 0.05
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.04
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 0.03


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