Gene Query: SPP1

Dataset Description Geneva Score
Energy Metabolism during Anchorage-Independence 560.15
Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer 388.63
Codon usage optimization in pluripotent embryonic stem cells [tRNA sequencing] 350.9
Role of cervicovaginal microbiota in genital inflammation 229.36
FOXD3 is a novel tumor suppressor in lung cancer 138.02
Rational targeting of cooperating layers of the epigenome yields enhanced therapeutic efficacy against AML 125.5
Identification of ZEB1-regulated gene expression changes in HCC827 human lung adenocarcinoma cells 119.71
Transcriptome analysis of U87 cells upon LINC00152 knockdown 113.24
Distinct roles of cohesin-SA1 and cohesin-SA2 in 3D chromosome organization  112.91
Gene Expression Profiling of SPOP Knocked Down Cell 110.67
Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures 106.94
RNA sequencing of BT142 and TS603 cell lines 102.23
Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas 102.23
Global Gene Expression Changes in Cholangiocytes Treated with TGF-beta 98.35
Alteration of the microRNA network during the progression of Alzheimer’s disease 96.67
Transcriptome-wide analysis of the role of HTLV-1 Tax PBM in T-Cells from infected humanized-mice (hu-Mice) 95.15
Regionally distinct astrocyte interferon signaling promotes blood-brain barrier integrity and limits immunopathology during neurotropic viral infection 93.04
RNA expression following TMPRSS11B overexpression or depletion 89.48
The Cushing's disease adipose gene expression profile reveals effects of long term glucocorticoids on adipose tissue lipid, protein and glucose metabolism 89.21
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 88.22
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [ribosome profiling] 86.17
Glioma Stem Cell Specific Super Enhancer Drives Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling 85.96
PARP3 is a promoter of chromosomal rearrangements and limits G4 DNA 81.64
Candidate genes and pathways downstream of PAX8 involved in ovarian high-grade serous carcinoma 80.85
Zika infected neural stem cells 80.07
Transcriptome analysis of Zika infected neural stem cells 80.07
WRN knockout effects upon gene expression in SW48 and OVK18 77.36
RNA-Seq from early time points in the kidney differentiation protocol 75.46
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 74.38
MARS Seq data from human cortical organoids 73.81
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 73.41
RNA-Seq and ATAC-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 71.39
RNA-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 71.39
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 70.43
High level DNA repair gene expression in human ES cells 70.19
Knockdown of FOXP1 promotes the development of lung adenocarcinoma 69.58
Gene expression profile of human iPSC-derived nephron progenitor cells 68.96
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses 65.53
Sequencing-based analyses characterize a tumor suppressive role of mir-1271 repressed by DNA hypermethylation in gastric cancer 64.08
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 62.57
Development of an In Vitro Human Liver System for Interrogating Non-Alcoholic Steatohepatitis 62.52
IgG immunocomplexes sensitize human monocytes for inflammatory hyperactivity via transcriptomic and epigenetic reprogramming in Rheumatoid Arthritis 62.29
Uridilation by TUT4/7 restricts retrotransposition of human Line-1s 62.0
Identification of Nrf2 regulated genes by RNA sequencing 61.52
Nrf2 regulated genes in A549 cells 61.52
Modeling and characterization of the dynamic gene regulatory networks underlying cancer drug resistance based on time-course RNA-seq data 60.88
Differential responses by human respiratory epithelial cell lines to respiratory syncytial virus reflect distinct patterns of infection control 60.59
JQ1 +/- Vemurafenib in BRAF mutant melanoma (A375) 60.54
The Role of Histone H3 Lysine 36 Methylation in Reprogramming of fibroblasts and on Induced Pluripotent stem Cell Generation 60.49
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 60.03
LncRNA NMR knockdown and overexpression in esophageal squamous cell carcinoma cell lines 59.9
High-Throughput Drug Screening identifies Pazopanib and Clofilium tosylate as effective treatments for malignant rhabdoid tumors 59.62
RNAseq to determine gene expression changes following depletion of SETDB1 in THP-1 AML Cells 59.28
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 59.12
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 59.09
Global transcriptional profiling changes upon knockdown of G9a in human non-small cell lung cancer cells 58.72
GATA3 enhances the neurogenic potential of primary human astrocytes after traumatic injury [exp2] 58.1
Generation of targeted homozygosity in the genome of human induced pluripotent stem cells 57.72
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 56.9
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 56.9
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 56.06
METTL3 promotes translation in human cancer cells 55.66
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells [RNA-seq] 55.45
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells 55.45
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells [RNA-seq] 55.45
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells 55.45
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 54.55
Identifying a novel candidate diagnostic and prognostic biomarker SPRR3 for oral squamous cell carcinoma via mRNA Sequencing and Bioinformatics 54.05
Global transcriptional profiling changes upon knockdown of LKB1 in human glioblastoma cell lines 53.42
Wnt5a and its downstream transcription factor Stat3 are therapeutic targets for diffuse intrinsic pontine gliomas 52.89
PNET animal model: new insights (II) 52.87
Generation of induced neural stem cells from urine derived cells by synthetic mRNA 52.86
miRNA-1343 attenuates pathways of fibrosis by targeting the TGF-beta receptors [RNA-seq] 52.38
RNA Expression Profile of Calcified Bicuspid, Tricuspid and Normal Human Aortic Valves by RNA Sequencing [TAV] 52.24
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition [RNA-Seq] 52.14
Krüppel-like Transcription Factor-10 (KLF10) Provides a Negative Feedback Mechanism to Suppress TGFβ-Induced Epithelial-to-Mesenchymal Transition 52.14
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 51.91
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock 51.67
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock [RNA-Seq] 51.67
Error-free and error-prone DNA repair gene expression through reprogramming and passage in human iPS cells 51.42
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 50.79
SF3B1 Degron knockdown RNA-seq 49.14
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 48.48
RNA-seq and Microarray in Transcriptome Profiling of Anterior Cruciate Ligament Tears: Implications for Prognostic Biomarkers Discovery 48.22
Lipid Nanoparticle-Mediated Delivery of Anti-miR-17 Family Oligonucleotide Suppresses Hepatocellular Carcinoma Growth 47.82
mRNA Profiling of miR-17 family inhibition using TuD lentiviral vector in HepG2 and SK-Hep1 hepatocellular carcinoma cell lines [RNA-Seq] 47.82
Total RNA sequencing of WT intestinal orgaonids. 47.81
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 47.75
Integrative analysis of mRNA and lncRNA profiles identified pathogenetic lncRNAs in esophageal squamous cell carcinoma 47.66
Integrating the Epigenome to Identify Novel Drivers of Hepatocellular Carcinoma 47.39
FOXP1 orchestration of ASD-relevant signaling pathways. 47.21
ASCL1 mediates neuronal differentiation of primary GBM stem cell cultures upon Notch signalling blockade [RNA-seq] 46.83
Gene expression profiling of human MSC-educated macrophages vs. classical macrophages from bone marrow and blood 46.67
Human Pancreatic Islets Expressing HNF1A Variant Have Defective β cell Transcriptional Regulatory Networks 46.47
Anti-inflammatory effect of indoleacrylic acid (IA) 46.42
A NIK-SIX signaling axis controls inflammation by targeted silencing of noncanonical NF-κB 46.35
Aberrant downstream mechanisms following loss of KMT2C and KMT2D in Pancreatic Ductal Adenocarcinoma 46.08
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 46.07
Gene expression profile of multiple myeloma cell lines treated with CB-5083 45.96
Transcriptomic profiles of nonpregnant and term pregnant human myometrial tissues 45.91
Nonpregnant and term pregnant human myometrial tissues 45.91
Gene expression profile of calcified and normal tricuspid aortic valves by RNA sequencing. 45.45
Aneuploidy triggers an immune response 45.42
RNAseq to determine whether bidirectional transcription occurs over transposable elements following depletion of SETDB1 in THP-1 AML Cells 45.14
Endometrial transcriptome and PGR cistrome in cycling fertile women 44.76
Endometrial transcriptome and PGR cistrome in cycling fertile women [RNA-seq] 44.76
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 44.72
Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors 44.69
Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing 44.56
Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols 44.43
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 44.24
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization [RNA-Seq] 44.19
Transcriptional Profiling Identifies Novel Regulators of Macrophage Polarization 44.19
RNA-sequencing of formalin fixed human primary melanoma tissue 44.14
Epigenomes and Transcriptomes of human monocytes from Hyper IgD Syndrome (HIDS) patients 44.14
An integrative network biology analysis identifies miR-508-3p as the determinant and a prognosis biomarker of the mesenchymal subtype ovarian cancer 43.56
Expression by CD133+ cells isolated from the adult human exocrine pancreas 43.46
mRNA and RNC-mRNA deep sequencing of three hepatocellular carcinoma cell lines 43.35
Gene expression in mature and immature human ES-derived beta cells, and sorted beta-cells from adult islets 43.27
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 43.1
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 42.9
The role of CFTR in islet function 42.61
Transcriptomic insights into human decidual and peripheral blood CD4 T cells 42.07
Genomic analysis of human parthenogenetic haploid ESCs (hPGES), normal human ESCs(H9) and human forskin fibroblast 42.0
mRNA expression data from human parthenogenetic haploid ESCs (hPGES), normal ESCs (H9) and human fibroblast 42.0
Primary human trophoblast from term placenta 41.66
Patient Derived Xenograft for Delivery of Precision Medicine in Castrate Resistant Prostate Cancer 41.65
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 41.16
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 40.93
Global transcriptional profiling changes upon knockout of USP22 in human Non-small cell lung cancer cells 40.69
Single-cell RNA-Seq Investigation of Foveal and Peripheral Expression in the Human Retina 40.54
Diverse Compounds from Pleuromutilin Lead to a Thioredoxin Inhibitor and Inducer of Ferroptosis 40.54
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 40.43
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 40.43
High-depth RNA sequencing of isogenic wild-type, PIK3CA-WT/H1047R and PIK3CA-H1047R/H1047R human iPSCs 39.97
Expression alterations induced by restoration of AXIN1 expression in SNU449 hepatocellular carcinoma cells 39.94
Transcriptome profiling of omental adipose tissues in human obesity by RNA-Seq 39.93
An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans. 39.85
RNA-seq analysis to identify the genes regulated by p53-SET interplay 39.83
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq 39.78
Global transcriptional analysis and genome-wide analysis of chromatin state in extended pluripotent stem cells, primed pluripotent stem cells, and naïve pluripotent stem cells 39.78
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 39.48
Depicting early human development and germ cell origin with porcine embryos 39.45
Differentially expressed genes during pancreatic bud differentiation in cellular aggregates 39.43
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels 39.42
Differentiation of Induced Pluripotent Stem Cells towards Mesenchymal Stromal Cells is Hampered by Culture in 3D Hydrogels [RNA-Seq] 39.42
Transcriptome of invasive mucinous adnocarcinoma of the lung and adjacent normal lung tissues from 6 patients based on RNA-seq method 39.2
Viral infection enhances NK cell activation via Type I dependent pathways and can be utilized to enhance influenza-specific monoclonal antibody therapies 38.92
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 38.75
Derivation of ventrical and atrial cardiomyocytes and maturation using biowires 38.56
Generation, transcriptome profiling, and functional validation of cone-enriched human retinal organoids 38.2
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 38.16
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells (wtRNA-Seq) 38.13
RNA Sequencing Reveals Immunosuppressive Role of Anthrax Lethal Toxin in Human Lung Epithelial and Monocytic Cells 37.85
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor 37.6
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain 36.97
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain [RNA-Seq] 36.97
CDK12 inhibition in Hep3B, Huh7 and SNU449 cells 36.84
High-Throughput Kinetic Analysis of Fractional Killing 36.5
Fibroblasts in cholesteatoma activate osteoclasts. 36.45
RNA-seq analysis of SKMEL28 melanoma cells following DIRC3 and IGFBP5 ASO knockdown 36.22
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 36.04
UPA-Seq: Prediction of functional lncRNAs using the sensitivities to UV-crosslinking 36.04
Transcriptome Analysis and Functional Identification of Adipose-Derived Mesenchymal Stem Cells in Secondary Lymphedema 35.93
Cooperative and Antagonistic Transcriptional Regulation by BRG/BRM [RNA-seq] 35.54
Co-regulation of transcription by BRG1 and Brm, two mutually exclusive SWI/SNF ATPase subunits 35.54
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 35.24
RNA-Seq profiling of days 0, 7 and 18 kidney organoids differentiated from three separate vials of starting material 34.96
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 34.84
Single-nucleotide-resolution mapping of HBV promoters using CAGE 34.7
Deletion of DXZ4 on the human inactive X chromosome eliminates superdomains and impairs gene silencing 34.68
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 34.59
Analyses of a panel of transcripts and construction of RNA networks in hepatocellular carcinoma 34.4
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 34.33
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 34.33
CD86 regulates a pro-survival signal in myeloma cells 34.28
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [RBM47 KD] 33.85
Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype 33.69
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 33.44
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 33.33
Genes regulated by SPDEF or FOXA3 in A549 lung carcinoma cells [RNA-seq] 33.11
Evolution of a transcriptional regulator from a transmembrane nucleoporin 32.38
RNA-seq in HepG2 and IMR90 cells 32.38
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 31.37
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 31.37
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination 31.15
Transcriptome sequencing analysis of BRAF-mutant melanoma metastases. 30.98
Transcriptome profiling of a mouse model of alveolar soft part sarcoma 30.91
Comparing gene expression in iPSC derived RPE from control and AMD donors 30.82
The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas 30.76
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks 30.64
Transcription elongation regulates genome 3D structure 30.59
RNA-seq expression data from EB-HSPC after AM580 treatment compated to DMSO-trated and FL-HSPCs 30.48
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 30.42
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq2] 30.32
High-throughput sequencing of the human hepatic progenitor cell niche in PSC and HCV. 29.75
Universal alternative splicing of noncoding exons 29.35
6mer seed toxicity in tumour suppressive microRNAs 29.21
RNA-sequencing of human peripheral blood mononuclear cells (PB MNCs) and induced neural progenitor cells derived from PB MNCs 29.11
Transcriptional effect of ETV1 knockdown in melanoma cells 28.96
Expression profiling by RNA-Seq of breast cancer samples from patients in walnut-consuming and control groups 28.94
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_TK] 28.92
The X-linked DDX3X RNA helicase dictates translation re-programming and metastasis in melanoma 28.88
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming (RNA-seq fibroblasts) 28.87
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming 28.87
Comprehensive RNA sequencing of healthy human endometrium at two time points of the menstrual cycle 28.81
Extensive remodeling of DC function by rapid maturation-induced epigenetic gene silencing 28.78
Extensive remodeling of DC function by rapid maturation-induced epigenetic gene silencing [RNA-Seq] 28.78
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons [RNA-seq] 28.69
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons 28.69
RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues 28.53
Efficient direct reprogramming of c-Kit− mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression 28.15
Compared performance of Affymetrix HTA arrays and Illumina RNAseq for the analysis of tumours 27.82
Compared performance of Affymetrix HTA arrays and Illumina RNAseq for the analysis of tumours [RNA-seq] 27.82
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 27.61
Human embryonic stem cells in E8 and AKIT culture medium 27.61
CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg] 27.56
NHLRC1 re-expression in cancer cells 27.24
ARID1A and ARID1B loss in HCT116 and TOV21G cells 27.21
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug [human] 27.17
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug 27.17
mRNA sequencing of the global effect of SOX2 on gene expression in hESC and hESC derived NPCs. 27.1
Hydroxychloroquine inhibits responses to group A streptococcus in peripheral blood mononuclear cells 27.02
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 27.01
Effect of circPTPRM on the biological behaviors of hepatocellular carcinoma cells in vitro and its clinical significance. 27.0
Reducing the structure bias of RNA-Seq reveals a large number of non-annotated non-coding RNA 26.86
Transcriptome profiling of H1-iCas9 cells grown on laminin and on MEFs 26.62
BI Human Reference Epigenome Mapping Project 26.5
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells 26.44
Evaluation of the immunogenicity of live-attenuated influenza vaccines in nasal epithelial cells in primary differentiated human nasal epithelial cells [RNA-Seq] 26.44
GCTM-5 positive and negative cells in pancreatic adenocarcinoma cell lines 26.41
Characterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer 26.3
Next Generation Sequencing Facilitates Quantitative Analysis of Retinoblastoma Transcriptomes 25.81
Identifying deer antler proliferation and mineralization genes using comparative RNA-seq 25.71
RNA sequencing of matched nephrectomy samples [RNA-seq] 25.65
Genome-wide maps of H3K36me3 in ccRCC and RNA-seq of matched nephrectomy samples 25.65
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 25.54
Distinct Pathological Signatures in Human Cellular Models of Myotonic Dystrophy Subtypes 25.47
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency (RNA-Seq) 25.46
Critical role of transient activation of human endogenous retroviruses during reprogramming toward pluripotency 25.46
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 25.4
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 24.03
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 24.01
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 24.01
SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate 23.93
RNA isoform screens reveal the essentiality and tumor suppressor activity of ultraconserved poison exons 23.72
RNA-seq data for non-targeting siRNA and CDK11 siRNA transfection in SHhES8 cells 23.63
Genome wide transcriptome analysis of palbociclib or GSK3326595 treated A375 cells [Palbociclib_GSK_RNASeq] 23.6
Epigenetic programming during monocyte to macrophage differentiation and trained innate immunity 23.48
Gene expression alterations of pancreatic intraepithlial neoplasia 23.3
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing (Total RNA sequencing) 23.29
Differential gene expression by suppression of either SOX2 or TP63 in KYSE70 human esophageal squamous carcinoma cell line. 23.28
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis 23.01
Endothelial TGFb signaling drives vascular inflammation and atherosclerosis [bulk RNA-Seq] 23.01
Aortic Valve Tissue: Stenosis vs. Sclerosis 22.88
The histone variant H3.3 G34W substitution in giant cell tumor of the bone link chromatin and RNA processing [RNA-seq] 22.78
SEUSS: A scalable screening platform to assess transcriptomic and fitness effects of transcription factor overexpression 22.7
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 22.48
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HOM] 22.42
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 22.35
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 22.34
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 22.3
Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx 22.3
Changes in human endometrial gland transcriptome over the window of implantation 22.15
Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic β-cell death 22.1
Molecular analysis of high-grade serous ovarian carcinoma with and without associated serous tubal intra-epithelial carcinoma [RNA-Seq; normal samples] 21.97
Exploring the gene expression profile upon FXR1 knockdown in H358 cells using RNA-seq 21.91
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 21.85
Transcriptome analysis reveals differential splicing events in IPF lung tissue 21.77
KLF6-dependent transcription in renal cancer cells 21.68
Global expression profiles in cardiac progenitor cells generated by ISX-9 21.35
Global mRNA expression profile in cardiac progenitor cells generated by ISX-9 21.35
Comparative Transcriptome analysis of hESCs- and iPSCs-derived lentoid body 21.22
Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma 21.17
Zika Virus Has Oncolytic Activity against Glioblastoma Stem Cells 21.13
Transcriptome analysis reveals determinant stages controlling human embryonic stem cell commitment to neuronal cells 21.11
Transcriptome profiling of 5 human adenocarcinoma cell lines 21.06
POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells 20.96
Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis 20.72
Differential gene expression of human melanoma cells [RNA-seq] 20.53
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 20.53
Overexpression and knockdown experiment for circCSNK1G3 20.38
Human iPSC-derived cells and microengineered Organ-Chip enhance neural development. 20.32
RNA-sequencing of human tendon after injury 19.96
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance 19.96
Next Generation Sequencing Facilitated Differential Transcriptome Study of melanoma cells transduced with Notch 1 Intracellular Domain (NICD) 19.91
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 19.81
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 19.81
Nucleotide excision repair capacity increases during differentiation of human embryonic carcinoma cells into neurons and muscle cells 19.73
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 19.72
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 19.71
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 19.71
A transcriptional regulatory network connects mitochondrial biogenesis and metabolic shift with stem cell commitment to hepatic differentiation 19.71
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 19.69
Apatinib preferentially inhibits Gefitinib-resistant lung cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway 19.6
RNA-seq analysis of gene expression patterns during hESC neural differentiation 19.2
hESC neural differentiation 19.2
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 19.2
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 18.99
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor [human RNA-seq] 18.93
Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor. 18.93
Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes 18.6
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 18.08
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 18.08
Targeted enhancer activation by a subunit of the integrator complex 18.04
A pooled single-cell genetic screen identifies regulatory barriers in the continuum of the epithelial-to-mesenchymal transition 17.97
Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines 17.95
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 17.85
Efficient derivation of microglia-like cells from human pluripotent stem cells 17.69
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 17.67
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 17.67
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 17.6
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_KD] 17.55
A systematic analysis of the time series gene expression in TGF-beta induced EMT by Next-generation sequencing 17.49
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 17.15
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 17.11
RNA Sequencing Analysis of villus tissues from unexplained recurrent spontaneous abortion patients and controls with induced abortions 16.92
The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis 16.72
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 16.54
Profiling gene expression changes in ovarian cancer cells seeded on 3D organotypic culture of omentum 16.36
Radiomic and gEnomic approaches for the enhanced DIagnosis of REnal Cancer (REDIRECt): A translational pilot study 16.33
Fixed tissue ChIP-Seq (FiT-Seq) of archived clinical samples reveals chromatin dynamics and tumor-specific enhancer profiles 16.32
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 16.3
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 16.3
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 1] 16.18
PANCR, the PITX2 adjacent noncoding RNA, is specifically expressed in human left atria and regulates PITX2c expression 16.1
Functional Haploid Human Oocytes Generated from Polar Body Genomes (RNA-Seq) 16.0
Functional Haploid Human Oocytes Generated from Polar Body Genomes 16.0
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived neurons 15.94
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 15.85
Single cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid  during virologically suppressed HIV 15.76
RNA-sequencing of highly pure synovial tissue macrophages reveals two distinct osteoarthritis subgroups that indicate different disease mechanisms. 15.73
RNA sequencing for lncRNA, miRNA and mRNA expression analysis in human laryngeal cancer 15.6
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes (RNA-seq) 15.51
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes 15.51
Human naïve pluripotent stem cells exhibit X chromosome dampening and X-inactivation (RNA-Seq) 15.51
Circular RNA expression signature of low-glucose-treated MIA PaCa-2 cells 15.44
Different Temporal Effects of Ebola Virus VP35 and VP24 Proteins on Global Gene Expression in Human Dendritic Cells 15.41
RNA-Seq characterization of human H1-derived NPC differentiation timecourse 15.2
RNA-sequencing of pediatric idiopathic dilated cardiomyopathy patients and healthy controls 14.98
mRNA-Seq profiling of human developing kidney 14.91
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [RNA-Seq] 14.82
Genome-Wide DNA Methylation Encodes Cardiac Transcriptional Reprogramming in Human Ischemic Heart Failure [DNA Methylation] 14.82
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC [Total RNA-Seq] 14.47
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC 14.47
Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies 14.39
Profiling of lung tumor-infiltrating CD8 T cells according to their expression status of CD39 14.36
Transcriptome analysis of human reninomas as an approach to understanding juxtaglomerular cell biology 14.04
Improving fibroblast characterization using single-cell RNA sequencing: an optimized tissue disaggregation and data processing pipeline 13.86
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy [RNA-Seq] 13.67
Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes is Associated with Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy 13.67
Global epigenomic reconfiguration during mammalian brain development 13.47
nELAVL HITS-CLIP in Alzheimer's Disease patients 13.42
H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 13.42
RNA-seq of H9-hESC derived human neural stem cells with combinations of mutant IDH1-R132H overexpression, P53 shRNA knockdown and/or ATRX shRNA knockdown 13.42
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 13.27
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 13.03
Quantitative profiling of the UGT transcriptome in human drug metabolizing tissues [Total RNA] 12.95
Effects of rFVIIIFc on human macrophages 12.94
Transcriptomes of oxLDL exposed trained monocytes 12.93
oxLDL exposed trained monocytes 12.93
Human macrophages exhibit high activity to clear intracellular biovar Microtus strain of Y. pestis 12.88
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 12.8
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 12.29
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 12.29
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 12.29
Deep sequencing of transcript levels in pluripotent stem cells and their differentiated derivatives in all three germ layers 12.17
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability] 12.09
Apoptosis enhancing drugs overcome innate platinum resistance in CA125 negative tumor initiating populations of high grade serous ovarian cancer 11.96
Subtle asymmetry of gene expression in embryonic and foetal human brains 11.9
Wnt1 silences CC/CXC motif chemokine genes in dendritic cells and induces adaptive immune resistance in lung adenocarcinoma 11.83
Ribosome profiling of A549 cells depleted of RPLP1 and RPLP2 and infected with DENV. 11.72
RNA sequencing of erythroid and granulomonocytic colonies differentiated from transduced bone marrow CD34+ cells expressing U2AF1 S34F mutation, U2AF1 wild-type or empty vector control 11.62
Cell responses to dysregulated VZV-induced cell-cell fusion 11.59
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 11.28
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 11.22
Aneuploidy-induced cellular stresses limit autophagic degradation. 11.07
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 10.85
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 10.85
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 10.53
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 10.37
mRNA sequencing of clinical-grade neural stem cells derived from human ES cells 10.36
APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa 10.18
Landscapes of gene translation in hepatocellular carcinoma tumors revealed by ribosome profiling 9.98
CSL RNA-Seq on HKC and SCC cell lines 9.89
CSL 9.89
Long noncoding RNA LNMAT1 promotes lymphatic metastasis in bladder cancer 9.72
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NfkB-dependent differentiation of AML cells 9.63
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 9.62
RNA sequencing of hiPSC derived neural crest populations from Familial Dysautonomia patients 9.37
iPSCs Reveal Protective Modifiers of the BMPR2 mutation in Pulmonary Arterial Hypertension 9.33
Dexamethasone inhibits respiratory syncytial virus-driven mucus production while increasing viral replication without altering antiviral interferon signaling 9.24
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 1) 9.08
Gene expression profiles of isogenic single-cell derived clones of BRAF-mutated SK-MEL-5 melanoma cell lines 9.08
cKIT+ sorted cells from 57-137 day old fetal testes and ovaries 9.04
RNA-Seq of cKIT+ sorted cells from 53-137 day old fetal testes and ovaries and RNA-Seq of TRA-1-81+ H1 and UCLA1 hESCs. 9.04
Single cell transcriptome of peritoneal cells 9.03
Novel Atherogenic Pathways from the Differential Transcriptiome Analysis of Diabetic Epicardial Adipose Tissue 8.99
LINE-2 transposable elements are a source of functional human microRNAs and target sites 8.79
The effect of insulin on mRNA transcription of human pluripotent stem cells 8.78
RNA-Sequencing shows novel transcriptomic signatures in failing and non-failing human heart 8.76
HLA peptides derived from tumor antigens induced by inhibition of DNA methylation for development of drug-facilitated immunotherapy 8.69
Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii 8.6
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 8.56
Next Generation Sequencing Analysis of Colorectal Cancer Tissue Transcriptomes 8.52
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 8.51
RNA-Seq of Breast and Ovarian Cancer Cell Lines 8.44
RNA-seq in endometrial stromal tumors 8.38
RNA-seq of UGP2 mutant human embryonic stem cells and in vitro differentiated neural stem cells 8.37
CD133hi, Notchhi, DP (double positive) and DN (double negative) in GBML8 and GBML20, both patient-derived glioblastoma tumorsphere cultures 8.32
Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis 8.31
Loss of endometrial plasticity in recurrent pregnancy loss 8.29
Loss of endometrial plasticity in recurrent pregnancy loss (RNA-Seq) 8.29
Genome expression analysis of Lung Progenitors matured in the presence of constitutively active or pharmacologically inhibited Glycogen Synthase Kinase 3 8.18
The chromatin modifier CHD8 targets autism risk genes during human neurodevelopment  8.0
Nucleoporin-mediated regulation of cell identity genes 7.99
Transcriptome analysis of eosinophilic and noneosinophilic chronic rhinosinusitis with nasal polyps reveals distinct lncRNA expression profiles 7.91
Differentially Expressed Genes for Atrial Fibrillation Identified using RNA Sequencing from Paired Human Left and Right Atrial Appendages. 7.86
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 7.78
A novel RAF kinase inhibitor with DFG-out binding mode: high efficacy in BRAF-mutant tumor xenograft models in the absence of normal tissue hyperproliferation 7.76
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 7.46
Comparison of microRNA Profiling Platforms 7.38
Comparison of microRNA Profiling Platforms (HTS) 7.38
microRNA-seq and RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 7.29
RNA-seq reveals changes in the astrocyte transcriptome following Borrelia burgdorferi infection 7.29
Select correlative genes involved in pathogenesis of idiopathic interstitial pneumonia by high-throughput sequencing analysis 7.16
Gene expression profiling in follicular lymphoma (FL) samples and paired transformed follicular lymphoma (tFL) (n=6 samples) 7.15
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. 7.15
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells 7.01
Dynamic developmental signaling logic underlying lineage bifurcations during human endoderm induction and patterning from pluripotent stem cells [Endoderm RNA-seq and ChIP-seq data sets] 7.01
MAIT cell RNA sequencing 6.98
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 6.98
Next Generation Sequencing identifying the dosage compensation state in human endometrial carcinoma and adjacent tissues 6.95
circNFIB suppresses lymphatic metastasis of pancreatic cancer 6.78
Transcriptomes of human monocytes after ex vivo exposure to uric acid 6.5
Reprogramming of Tumor-infiltrating Immune Cells in Early Stage of NSCLC 6.49
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 6.48
Next Generation Sequencing Study of Circadian Changes in Transcriptome of Human Pineal Gland 6.43
Proteomics identifies a marker signature of MAPKi resistance in melanoma 6.41
The cytokine environment influence on human skin-derived T cells 6.23
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 6.16
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 5.96
Generating Patterned Kidney Organoids for Studying Development and Diseases [bulk RNA-Seq] 5.81
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 5.7
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 5.63
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes 5.61
Human ovarian granulosa cell transcriptome 5.43
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 5.37
Mutant p63 disrupts the key specification switch from the multipotent cell state to stratified epithelia during epithelial differentiation/in ectodermal dysplasia disorders 5.23
Expression changes in melanoma cell lines pre MAPKi treatment vs. post-MAPKi resistance (RNA-seq_CellLine.batch2) 5.21
Transcriptomic profiling of nasopharyngeal carcinoma (NPC) and normal control samples 4.82
Transcriptomic profiling of mRNA and miRNA from nasopharyngeal carcinoma (NPC) and normal control samples 4.82
A Low-cost Multiplex Biomarker Assay Stratifies Colorectal Cancer Patient Samples into Clinically-relevant Subtypes: Singapore Cohort RNA-seq 4.67
A Low-cost Multiplex Biomarker Assay Stratifies Colorectal Cancer Patient Samples into Clinically-relevant Subtypes 4.67
A cell cycle-based functional screen to identify lncRNA-based cancer biomarkers 4.57
Next Generation Sequencing Facilitates Quantitative Analysis of mesoderm posterior bHLH transcription factor 1(MESP1)+ and MESP1- cells' Transcriptomes 4.54
Zika virus infection reprograms global transcription of host cells to allow sustained infection 4.22
Hepatocyte maturation 4.18
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 4.04
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES [RNA-seq] 3.94
SIGNAL INTEGRATION AND TRANSCRIPTIONAL REGULATION OF THE INFLAMMATORY RESPONSE MEDIATED BY THE GM-/M-CSF SIGNALING AXIS IN HUMAN MONOCYTES 3.94
Epigenomic plasticity enables human pancreatic alpha to beta cell reprogramming 3.78
Common inflammatory pathways between NEC and Crohn's disease 3.67
A single-cell transcriptome atlas of the human pancreas 3.66
Genome wide impact of loss of mechanoluminal stimulation on neonatal intestine 3.6
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations 3.37
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq] 3.37
Human ES Cell-derived Hepatoblasts are an Optimal Lineage Stage for HCV Infection 3.3
Urinary sediment transcriptomic and longitudinal data to investigate renal function decline in type 1 diabetes 3.12
Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq 2.97
Increased Neanderthal ancestry in genomic regions associated with lipid catabolism in contemporary Europeans 2.81
RNA seq_PDX2_SHP099 2.59
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 2.45
Gene activation precedes DNA demethylation in response to infection in human dendritic cells 2.45
EGR1-controlled transcriptome of T HESCs 2.35
Finding missing proteins from epigenetically manipulated human cells 2.3
Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing analysis 2.21
Human Induced Pluripotent Stem Cells Recapitulate Breast Cancer Patients’ Predilection to Doxorubicin-Induced Cardiotoxicity 2.07
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 2.03
Transcriptomic analysis to functionally map the intrinsically disordered domain of EWS/FLI [Experiment 1] 1.93
Transcriptomic analysis of frontal fibrosing alopecia 1.9
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 1.8
Single Cell RNASeq profiling of stromal vascular fraction from Subcutaneous and visceral adipose tissue 1.71
Expression patterns in chronic thromboembolic pulmonary hypertension 1.7
Transcriptomic Analysis of Endothelial Cells from Fibrovascular Membranes in Proliferative Diabetic Retinopathy 1.64
Comparison of 7 small cell lung cancer PDX models, cultured ex vivo, for response to LSD1 inhibitor RG6016/ORY1001 1.41
Functional astrocytes differentiated from hiPSCs 1.32
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 1.28
Gene Expression Profile of human hepatocellular carcinoma by RNA sequencing 1.18
Genomic profiling of biliary tract cancer cell lines reveals molecular subtypes and actionable drug targets 0.98
RNA expression profiles comparing primary and omental ovarian carcinoma samples 0.96
Transcriptional profiling of healthy, eutopic and ectopic endometrial organoids 0.85
Gene profiling of human adult and pediatric liver cancer cells 0.62
The phosphatidylinositol 3-kinase pathway as a potential therapeutic target in bladder cancer 0.59
Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas 0.38
Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas [RNA-seq] 0.38
Trascriptome of thyroid cancer-induced macrophages 0.32
Gene Expression Signature in Adipose Tissue of Acromegaly Patients 0.25
Whole Transcriptomic Sequencing of Metastatic Castration Resistant Prostate Cancer Samples 0.1
Expansion of adult human pancreatic tissue yields organoids harbouring progenitor cells with endocrine differentiation potential 0.01


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