Gene Query: SYNGAP1

Dataset Description Geneva Score
Suppression of NAF-1 in Breast Cancer Cells Reduces their Tumorigenicity by Interfering with Cellular Iron Distribution and Metabolism and Ensuing ROS Formation and Apoptosis 179.15
AMPK signaling for naïve pluripotency [Hs] 30.72
AMPK signaling for naïve pluripotency 30.72
Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche 29.91
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling 26.79
Gene expressions of H9s in different culture systems 26.42
Intrahepatic MAIT cell gene expression revealed by RNA-seq 23.66
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging 23.59
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 23.36
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 23.06
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq2] 22.92
21.74
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 20.59
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 20.59
RNA-seq of naive and primed ES cells (NHSM) 20.41
Silencing SPIB in attached and floating state of H1703 lung cancer cells 19.89
RNA sequencing analysis of triple cytokine-captured human CD4 T cells 19.24
IL-11 neutralising therapies for the treatment of nonalcoholic steatohepatitis 18.66
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 18.65
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium 18.03
Waterpipe Smoking Induces Epigenetic Changes in the Small Airway Epithelium [RNA-Seq] 18.03
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 17.39
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 16.49
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 16.39
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 16.32
The effect of engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 16.06
Genetic disruption of COX-1 inhibits multiple oncogenic pathways 15.89
Dissecting the dynamics of signaling events in the BMP,WNT and NODAL cascade during self-organized fate patterning in human gastruloids 15.4
Differential gene expression profiles in imatinib-resistant cell lines 15.31
RNA-seq of PC3 prostate cancer cell line xenografts in mice administered the ghrelin receptor antagonist [D-Lys3]-GHRP-6 or PBS for two weeks 14.47
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5’ and 3’ Ends of Genes 14.28
Next Generation Sequencing Facilitates Quantitative Analysis of Retinoblastoma Transcriptomes 14.16
Transcriptome analysis of human lung epithelial cells 13.97
Maturing an Enteric Nervous System in Human Intestinal Organoid-derived Tissue-Engineered Small Intestine 13.83
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells 13.74
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator 13.66
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator [RNA-seq] 13.66
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 13.58
Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of binding sites in a cell type-specific manner 13.2
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 13.14
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 13.1
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 13.05
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 13.05
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 12.94
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 12.93
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells 12.88
EZHIP constrains Polycomb Repressive Complex 2 activity in germ cells (RNA-Seq) 12.88
Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin 12.81
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 12.56
ZNF131 suppresses centrosome fragmentation in Glioblastoma stem-like cells through regulation of HAUS5 12.53
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 12.46
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 12.46
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell type specificity 12.27
Regulation of protein translation during mitosis 12.18
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 12.11
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 12.06
Global gene expression profile of dasatinib-resistant RCH-ACV cells 11.94
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia 11.91
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [RNA-seq] 11.91
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 11.89
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 11.84
The Unfolded Protein Response Regulator, ATF6, Promotes Mesodermal Differentiation 11.59
Histone Demethylase-Assisted Somatic Cell Nuclear Transfer Facilitates Derivation of Human Pluripotent Stem Cells 11.51
Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome 11.4
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 11.34
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 11.19
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 11.19
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 11.16
Transcriptome analysis of human reninomas as an approach to understanding juxtaglomerular cell biology 11.1
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells 11.02
Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [ChIP-Seq & RNA-Seq] 11.02
High-throughput RNA sequencing of human preovulatory cumulus and mural granulosa cells (mRNA) 10.83
Small RNA-seq of human granulosa cells reveals miRNAs in FSHR and aromatase genes 10.83
Comparative genome-wide analysis of human BM IL3Rα-high precursors show a more MΦ-, DC- and OC committed gene expression profile, as compared to IL3Rα-low precursors 10.6
AUF-1 affected genes in human skin cells 10.56
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 10.54
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 10.49
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 10.31
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 10.21
RNA-seq analysis of YFV-17D specific and total naive CD8 T cells in humans 10.2
The regulartory role of ZCCHC24 in splicing machinery 10.13
Gene expression profile of human iPSC-derived nephron progenitor cells 10.09
RNA-sequencing based transcriptome-wide expression profiling of Cynomolgus monkey and human IPSCs in vitro differentiated into endothelial cells 10.06
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros 10.03
circRNA-sequencing 10.03
Differentially expressed vascular development genes for iPSC-ECs from CDI 9.93
Total RNA sequencing of APC mutant and wt colonic organoids 9.86
RNA-seq of young and quiescent MRC-5 human fibroblasts 9.81
Characterization of sperm lncRNA and its differently expression in the sperm of asthenozoospermic patients 9.77
Bone marrow-derived and dental pulp-derived human mesenchymal stem cell RNA-Seq 9.67
Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression 9.66
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [ribosome profiling] 9.52
Monitoring Nivolumab binding as a method to clarify the residual therapeutic effects and to characterize the immune profile in antibody bound T cells in previously treated non-small cell lung cancer patients 9.51
RNA-seq of naive and primed ES cells 9.5
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 9.47
RNA-seq analysis of A2780 and OVCAR3 human ovarian cancer cell lines after overexpression of collagen type XI alpha 1 (COL11A1) 9.43
The evolution of N6-methyladenosine in primates 9.31
Transcriptome data from human endocrine cells recovered from mouse grafts with pre-engraftment controls 9.28
POLR3G Dependent PolyA+ and smallRNA Transcriptomes in Human Pluripotent Stem Cells 9.17
nELAVL HITS-CLIP in Alzheimer's Disease patients 9.16
Human co-transcriptional splicing kinetics and coordination revealed by direct nascent RNA sequencing 9.09
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells 9.03
Tumor exosome integrins determine organotropic metastasis 8.93
Deletion of DXZ4 on the human inactive X chromosome eliminates superdomains and impairs gene silencing 8.86
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 8.85
Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1 [RNA-seq] 8.85
IMP3 regulated gene expression in breast cancer cells 8.72
RNA polymerase in pre-B-ALL cell lines 8.7
Transcriptome sequencing of K-562 cells 8.69
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 8.62
Hyper-excitability of Neurons generated from Patients with Bipolar Disorder 8.56
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure 8.54
Epigenomic landscape during organ formation in human early embryos 8.51
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 8.49
Altering cancer transcriptomes using epigenomic inhibitors [RNA-Seq] 8.44
Altering cancer transcriptomes using epigenomic inhibitors 8.44
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of human mesenchymal stem cells differentiation from human embryonic stem cells and adult bone marrow mesenchymal stem cells 8.43
Cancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor development 8.35
High-Throughput Drug Screening identifies Pazopanib and Clofilium tosylate as effective treatments for malignant rhabdoid tumors 8.33
Transcriptional alteration after ionizing radiation exposure in human fibroblasts, iPSCs and NPCs 8.31
Expression and functions of long noncoding RNAs during human T helper cell differentiation 8.28
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family (RNA-seq) 8.26
Regulation of DNA methylation landscape in human somatic cell reprogramming by miR-29 family 8.26
Induced pluripotent stem cell modeling of bone marrow failure and MDS identifies therapeutic targets 8.15
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons [RNA-seq] 8.11
A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons 8.11
Comprehensive molecular phenotypic effects of the large deletion on chromosome 22q11.2 8.11
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 8.09
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer 8.01
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes. 8.01
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes [RNA-seq] 8.01
The stress granule transcriptome reveals principles of mRNA accumulation in stress granules. 8.0
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [short_hairpins_RNA-seq] 7.98
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis[Ribosome Profiling] 7.85
Pancreatic cancer-derived exosomes induce apoptosis of T lymphocytes through the p38 MAPK signal transduction pathway 7.79
RNA profiling Analysis of the Serum Exosomes Derived from Active and Latent M.tuberculosis infectious Patients 7.78
Safeguarding nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis 7.77
SIRT7 Antagonizes TGF-β Signaling and Inhibits Breast Cancer Metastasis 7.74
Whole transcriptome analysis of PBMCs stimulated with either a P. aeruginosa phage PNM lysate or with its bacterial host P. aeruginosa 7.66
RNA-seq analysis of AML cells in response to ASLAN003 7.59
Gene expression in PANC1 cells treated with Rakicidin 7.51
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 7.49
PTP4A1 phosphatase is overexpressed in systemic sclerosis fibroblasts and promotes TGFb signaling 7.45
Deep sequencing of transcript levels of human embryonic stem cell derived mesothelium (epithelial and mesenchymal forms) and mesothelium from neonatal mouse E15.5 of the heart, lung, liver and gut and ChIP-seq data of the mesenchymal form of mesothelium 7.45
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 7.44
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 7.36
DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [uvCLAP CLIP-seq] 7.36
Differetially expressed genes after hTR overexpression in U2OS cells 7.34
Analysis of active enhancers and direct androgen receptor target genes in VCaP prostate cancer cells 7.33
Total RNA sequencing of WT intestinal orgaonids. 7.3
Multiple waves of transcriptome changes during extended hypoxic induction in human pulmonary microvascular endothelial cells 7.26
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 7.23
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 7.23
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 7.22
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 7.22
iPSC-Derived Cholangiocytes 7.2
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 7.2
Transcriptomic Dynamics during Differentiation Process of Human Pluripotent Cells into Hepatocyte-like Cells 7.2
Differential expression of human parthenogenic stem cells, neural stem cells and DA progenitors. 7.19
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 7.19
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line 7.16
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line [RNA-Seq] 7.16
Next Generation Sequencing Facilitates Quantitative Analysis of mesoderm posterior bHLH transcription factor 1(MESP1)+ and MESP1- cells' Transcriptomes 7.14
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells 7.13
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 6.95
Reversing Abnormal Neural Development by Inhibiting OLIG2 in Down Syndrome Human iPSC Brain Organoids and Neuronal Mouse Chimeras 6.95
RNA expression in primary huamn muscle cells treated with 1,25(OH)2D3 or vehicle 6.89
mRNA and miRNA expression in primary human muscle cells treated with 1,25(OH)2D3 or vehicle 6.89
Heterozygous mutations in SMARCA2 lead to impaired neurogenesis due to global retargeting of SMARCA4 6.86
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 6.86
Targeted enhancer activation by a subunit of the integrator complex 6.83
MEIS1 regulates hematopoiesis in hPSCs 6.81
Transcriptomic profiles of nonpregnant and term pregnant human myometrial tissues 6.79
Nonpregnant and term pregnant human myometrial tissues 6.79
RNA-seq of shEZH2 cells 6.74
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 6.69
Improved LCL to iPSC reprogramming: RNA Analysis of LCLs, reprogrammed iPSCs, and differentiated NSCs reveal potential regulatory and functional processes involved in these cellular transitions. 6.64
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 6.63
Characterization and therapeautic application of mesenchymal stem cells with neuromesodermal origin from human pluripotent stem cells 6.6
A Unique Epigenomic Landscape Defines Human Erythropoiesis (RNA-seq) 6.56
A Unique Epigenomic Landscape Defines Human Erythropoiesis 6.56
Hierarchy of mono- and bi-allelic TP53 alterations in Multiple Myeloma cell fitness 6.56
Differentiation enhances Zika virus infection in neuronal brain cells 6.56
Next Generation Sequencing Study of Circadian Changes in Transcriptome of Human Pineal Gland 6.54
Lysine benzoylation is a novel histone mark 6.54
Lysine benzoylation is a novel histone mark [RNA-seq] 6.54
Reprogramming by de-bookmarking somatic transcriptional program via targeting the BET bromodomains 6.51
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 6.5
Human Pancreatic Islets Expressing HNF1A Variant Have Defective β cell Transcriptional Regulatory Networks 6.45
RNA-sequencing with micro-dissected boundary organoid into anterior, posterior, and boundary regions 6.42
Role of FGFR1 in neuronal devlopment 6.39
Functional Importance of eRNAs for Estrogen-dependent Gene Transcriptional Activation 6.39
Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells 6.38
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies 6.38
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies [RNA-Seq] 6.38
BACH2 in human plasma cell fate decision 6.36
The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis 6.34
DJ-1 is dispensable for human stem cell homeostasis 6.32
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation (RNA-Seq) 6.19
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation 6.19
In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells 6.17
A novel CD4+ T cell population expanded in SLE blood provides B cell help through IL10 and succinate 6.13
Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation 6.12
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 6.06
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 6.05
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells 6.0
UTX and 53BP1 co-regulate genetic programs for neural differentiation of human embryonic stem cells [RNA-seq] 6.0
LIN28A modulates splicing and gene expression programs in breast cancer cells [RNA-Seq] 6.0
LIN28A modulates splicing and gene expression programs in breast cancer cells 6.0
Treatment Paradigms for Retinal and Macular Diseases Using 3-D Retina Cultures Derived From Human Reporter Pluripotent Stem Cell Lines 5.97
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 5.97
IGF2BP3 controls cancer cell invasiveness by modulation RISC function 5.93
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray 5.91
Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray [RNA-Seq] 5.91
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 5.91
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 5.91
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 5.89
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 5.89
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 5.78
RNA-Sequencing data of Varicella Zoster Virus (VZV)-infected human dermal fibroblasts (HDF) 5.78
Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells 5.76
Human T-cell lymphoblastic lymphoma samples and control thymuses 5.74
RNA-Seq in human T-cell lymphoblastic lymphoma samples and control thymuses 5.74
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 5.71
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 5.67
Regulating Interleukin-2 activity with engineered receptor signaling clamps 5.65
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) of BJ cells treated with Nutlin-3a, an MDM2 inhibitor, which induces p53. 5.64
TGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity 5.56
RNA-Seq of cKIT+ sorted cells from 16-16.5 week old fetal testes and ovaries and RNA-Seq of TRA-1-60+ H1 hESCs 5.51
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 5.47
ARID1A and ARID1B loss in HCT116 cells 5.43
Transcriptional profile in human S. haematobium infection 5.37
Defining a microRNA-mRNA targetome for calcineurin inhibitor induced nephrotoxicity 5.36
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 5.33
SETBP1-WT and SETBP1-G870S epigenetic landscapes 5.33
Next Generation Sequencing Facilitates Quantitative Analysis of Health donors and SLE patients' PBMC Transcriptomes 5.32
SOX10 Single Transcription Factor Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells 5.28
High-efficiency RNA-based reprogramming of human primary fibroblasts 5.27
Effect of BCL11B overexpression on transcriptome of T-cell acute lymphoblastic leukemia (T-ALL) cells 5.21
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 5.2
Paxillin regulates genomic networks in prostate cancer [PC3] 5.19
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 5.15
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 5.15
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 5.13
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 5.11
Human pluripotent stem cell-derived brain tumor model uncovered embryonic stem cell signature as a key driver in atypical teratoid/rhabdoid tumor (RNA-Seq) 5.1
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 5.08
Functional role of CPPED1 in trophoblasts. 5.08
Widespread Transcription beyond mRNA 3’ Ends Yields Abundant Regulatory RNAs 5.03
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 5.01
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 5.01
Clinker: visualizing fusion genes detected in RNA-seq data 4.97
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells [RNA-seq] 4.96
ETV4 is necessary for estrogen signaling and growth in endometrial cancer cells 4.96
Analysis of transcriptome changes following SOX2 knockdown in three different Ewing sarcoma cell lines 4.96
Effector and regulatory T cells roll at high shear stress by inducible tether and sling formation 4.95
Anaylsis of the effect of down-regulation of the EWS-FLI1 fusion protein in Ewing Sarcoma cells by RNA-seq. 4.91
MYOD Remodeling of the Genome Architecture during Myogenic Conversion of Somatic Cells 4.89
MYOD Gene Expression Regulation during Myogenic Conversion of Fibroblasts 4.88
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 4.8
Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation 4.78
RNA-seq characterization of downstream effects of upregulating SMN2 via down-regulating PRC2 or blocking the PRC2:SMN-AS1 interaction with a mixmer oligonucleotide 4.76
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts 4.75
Human embryonic stem cells in E8 and AKIT culture medium 4.69
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 4.69
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 4.69
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 4.67
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 4.67
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 4.67
Transcriptome profiling of H1-iCas9 cells grown on laminin and on MEFs 4.61
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [RNA-seq] 4.58
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 4.57
High level DNA repair gene expression in human ES cells 4.5
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [RNA-seq] 4.48
Rescue of Fragile X syndrome by DNA methylation editing of the FMR1 4.48
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 4.42
Differential gene expression analysis between proliferating and quiescent human dermal fibroblasts 4.41
Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons 4.36
CD1c+ dendritic cell activation by Plasmodium falciparum-infected red blood cells 4.35
Repurposing of promoters and enhancers during mammalian evolution 4.32
m6A-dependent regulation of messenger RNA stability 4.27
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 4.26
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 4.22
Heterozygous and homozygous knock-in of PIK3CA-H1047R into human iPSCs 4.19
Lineage specific differentiation is influenced by state of human pluripotency 4.16
Lineage specific differentiation is influenced by state of human pluripotency [RNA-seq] 4.16
Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells 4.13
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-Resistant, sensitive and healthy control 4.1
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 4.09
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 4.08
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape 4.08
High-depth RNA sequencing of isogenic wild-type, PIK3CA-WT/H1047R and PIK3CA-H1047R/H1047R human iPSCs 4.05
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas [Human RNA-Seq] 4.04
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas 4.04
RNA sequencing with KSHV infection and enrichment for circular RNAs 4.04
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells 4.01
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells [RNA-seq] 4.01
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 3.95
Expression data from fresh human embryonic lung epithelial tip and stalk cells and cultured organoids derived from tip and stalk. 3.93
Proliferation-correlated expression 3.9
RNA-seq of SOX5 overexpressing primary human neuronal progenitors 3.84
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 3.84
Long non-coding RNA profiling of human lymphoid progenitors reveals transcriptional divergence of B cell and T cell lineages 3.82
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 3.82
PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs 3.81
A549 cell transcriptome responses to infection with H7N9 influenza virus 3.79
Transcriptomic insights into human decidual and peripheral blood CD4 T cells 3.78
Transcriptional profiling of CD45RO+CD57+CD4+ T cells 3.78
X-Ray induced DNA-Hydroxymethylation changes 3.77
C9/ALS Human Embryonic Stem Cells and C9/ALS Induced Pluripotent Stem Cells 3.76
Primary Human B-cell Temporal Response to CD40L Stimulation 3.72
Induced DNA demethylation, genome instability and transcription 3.7
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 3.7
Hydroxychloroquine inhibits responses to group A streptococcus in peripheral blood mononuclear cells 3.63
Three congruent human Schwann cell models of CMT1A reveal a converged phenotype 3.59
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 KO] 3.58
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 3.51
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 3.46
The m 6 A-methylase complex recruits TREX and regulates mRNA export. 3.46
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 3.46
RNA-seq of ASXL2 shRNA KD in SKNO-1 cells 3.43
Re-Wiring 3D Nuclear Architecture by a Single Transcription Factor during Somatic Cell Reprogramming 3.42
Human naïve pluripotent stem cells exhibit X chromosome dampening and X-inactivation (RNA-Seq) 3.42
The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells 3.34
Identification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression 3.34
Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models 3.28
The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis 3.2
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies 3.2
Pharmacological Induction of a Progenitor State for the Efficient Expansion of Primary Human Hepatocytes 3.17
SQSTM1/p62-directed metabolic reprogramming is essential for normal neurodifferentiation 3.17
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 3.09
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 3.07
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 3.07
Gene expression analysis of breast cancer cell-lines 3.04
Gene expression and genome-wide location analysis of breast cancer cell-lines 3.04
Expression profile of GIST48 cells with siETV1 or siFOXF1 knockdown 3.0
FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST) 3.0
Evaluation of the effectiveness of semen collection and sperm purification methods for spermatozoa transcript profiling 2.99
Analyses of T-ALL (COG study) 2.94
RNA sequencing of T-ALL (COG study) 2.94
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 2.93
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 2.92
RNA-seq data for non-targeting siRNA and CDK11 siRNA transfection in SHhES8 cells 2.86
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 2.78
Antiviral and anti-inflammatory properties of novel anti-HIV candidate ABX464 promotes specifics RNA splicing while preserving cellular RNA integrity. 2.76
Global transcriptome analysis of WT versus HEB-/- hESCs 2.76
RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms, and GTPase binding in bipolar disorder 2.73
A comprehensive gene expression analysis identifies novel immune signatures in cesarean-born infants 2.63
Analysis of transcrptomes of Danon patient derived hiPSC-cardiomyocytes by RNA-deep Sequencing 2.61
Functional astrocytes differentiated from hiPSCs 2.57
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 2.57
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 2.53
FMR1 reactivating treatments in Fragile X iPSC-derived neural progenitors in-vitro and in-vivo 2.52
SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate 2.5
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 2.5
Genome-wide mapping of TEL-AML1 targets in acute leukemia 2.49
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 2.48
Reprogramming of dermal papilla cell intact gene signature with 3D culture and Lef-1 overexpression 2.39
Molecular Criteria for Defining the Naive Human Pluripotent State 2.35
Diffuse Large B Cell Lymphoma cell line with Acquired Resistance to PI3Kδ Inhibitor Idelalisib 2.32
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers (RNA-Seq) 2.31
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers 2.31
Whole blood RNAseq from Generalised Pustular Psoriasis patients and healthy individuals 2.28
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain [RNA-Seq] 2.27
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain 2.27
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers [RNA-Seq] 2.24
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers 2.24
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 2.19
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 2.15
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma 2.15
The role of miR-17-92 in the miRegulatory landscape of Ewing Sarcoma (RNA-Seq) 2.15
The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC derived cardiomyocytes. 2.11
RNA-Seq analysis of human Tr1, Tregs and IL10neg cells 2.1
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 2.08
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 2.08
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 2.06
Analysis of MGE Transcriptomes with or without Ctnnb1 knockout in human through RNA Sequencing 2.01
Human ovarian granulosa cell transcriptome 1.98
The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains 1.98
Recovery and analysis of nascent RNA 1.98
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 1.96
STX4 Over-Expression in Human islets 1.96
Gene expression profile difference among renal location in a stone former 1.92
Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming 1.91
naive T cell heterogeneity after neonatal thymectomy 1.9
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation 1.86
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation [RNA-Seq] 1.86
RNA-seq study reveals unique transcriptome expression in systemic lupus erythematosus patients with distinct autoantibody profile 1.85
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 1.85
Activity-dependent transcriptional changes in human neurons 1.85
FOXO1 is an oncogenic mediator in AML1-ETO leukemia 1.81
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment [RNA-Seq] 1.81
Rapid Irreversible Transcriptional Reprogramming in Human Stem Cells Accompanied by Discordance between Replication Timing and Chromatin Compartment 1.81
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 1.79
Gene expression profile of regenerated CD8αα T cells and CD8αβ T cells from LMP2 T-iPSCs 1.79
Transcriptome analysis of SKI knock-out in HL60 cells 1.78
Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1 1.78
The control of rRNA synthesis during the directed differentiation of human embryonic stem cells precedes heterochromatin formation. 1.76
Generation of Brain Region-specific Organoids using a Miniaturized Spinning Bioreactor and Modelling ZIKV Exposure 1.73
Function and hormonal regulation of GATA3 in human first trimester placentation 1.71
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 1.67
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells [RNA-Seq] 1.66
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells 1.66
RNA splicing alteration on glioblastoma and normal neural stem cells 1.65
Radiation enhances melanoma response to immunotherapeutic and synergizes with benzodiazepines to promote improved anti-tumor activity 1.63
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal [RNA-Seq] 1.63
Identification of a dynamic core transcriptional network in t(8;21) AML regulating differentiation block and self-renewal 1.63
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing (Total RNA sequencing) 1.57
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 1.56
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks 1.54
RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells II 1.54
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 1.53
CHD1 regulates cell fate determination by activation of differentiation-induced genes 1.48
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 1.46
Functional separation of IL7Rα/KLRG1-defined CD8+ T cell populations in humans 1.46
Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria 1.44
RNA-seq of hiPSCs-derived NPCs from 3 pairs of dizygotic discordant twins for Congenital Zika syndrome 1.44
Cancer-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1 1.44
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 1.39
The age and genomic integrity of neurons after cortical stroke in humans 1.32
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity 1.24
Increased Neanderthal ancestry in genomic regions associated with lipid catabolism in contemporary Europeans 1.23
Expression changes in MAPKi resistant M229 melanoma lines co-cultured with PD-1 overexpressing HEK293T cells [CellLine.FPKM.batch5] 1.21
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] 1.21
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 1.21
Transcriptome profiling of de-differentiated chondrocytes over-expressing miR-138 or miR-181ab1 during osteogenic induction 1.18
A myogenic double reporter human pluripotent stem cell line allows prospective isolation of skeletal muscle progenitors 1.18
Human macrophages exhibit high activity to clear intracellular biovar Microtus strain of Y. pestis 1.18
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HOM] 1.17
Functional characterization of human T cell hyporesponsiveness induced by CTLA4-Ig 1.12
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 1.07
Whole-transcriptome profilings between a pair of HCA7-derived KRAS-wildtype cetuximab sensitive and resistant colon cancer cells from 3D culture 1.07
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [GSKJ4_RNA-seq] 1.04
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 1.03
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 1.02
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 0.99
Induction of Cardiomyocyte Proliferation [pz-822_human] 0.99
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 0.99
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 [stranded] 0.99
Specific molecular signatures underlie response to decitabine in CMML 0.94
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 0.94
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 0.91
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 0.91
RNA-Seq of the corpus callosum from 12 individuals 0.89
Dynamic gene expression in T-ALL following treatment and release of gamma-secretase inhibition [GRO-Seq] 0.86
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 0.84
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 0.83
Engineering Patient-Specific Tissue Implants 0.82
Critical role for Lymphocytes in Producing FLT3LG in Tumors and Driving Checkpoint Therapy-Receptive Immune Microenvironments 0.81
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 0.8
Transcriptome profiling of omental adipose tissues in human obesity by RNA-Seq 0.76
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 0.72
Dissecting neural differentiation regulatory networks through epigenetic footprinting 0.72
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 0.71
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 0.71
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 [RNA-seq] 0.71
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 0.67
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 0.66
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 0.65
Quantitative Proteomics Reveals a Unique Wiring of Signaling Pathways that Protects Human Regulatory T Cell Identity 0.64
RNA sequencing of hiPSC derived neural crest populations from Familial Dysautonomia patients 0.63
CD161+ Tconv and Treg share transcriptome and display a migratory phenotype which is modified at the inflamed site 0.62
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 0.61
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML [RNA-Seq human] 0.6
MEIS2 is a novel oncogenic partner in AML1-ETO positive AML 0.6
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 0.58
CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Humans 0.57
Myc activation coordinates gene transcription and protein translation responses 0.56
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 0.56
Glioblastoma stem cells infected by ZIKA virus 0.54
iPSC derived motor neuron cultures from C9ORF72 carriers 0.53
RNAseq of human monocyte cell line (U937-Cas9) WT or IRF2KO 0.52
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 0.51
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 0.51
Genome-wide maps of chromatin state and mRNA expression patterns in leukemic cell lines 0.49
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 0.47
RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells I 0.46
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes 0.44
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 0.44
Aberrant splicing in B-cell acute lymphoblastic leukemia [B-ALL] 0.43
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) [RNA-seq] 0.38
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) 0.38
Subtle asymmetry of gene expression in embryonic and foetal human brains 0.37
Zika virus directly infects human peripheral neurons and induces cell death 0.29
Transcriptomic analysis of human iPS cells derived from fragile X syndrome patients during neural differentiation 0.26
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 0.25
Identification of metabolically distinct adipocyte progenitor cells in human adipose tissues 0.25
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 0.25
Epigenetic and transcriptional analysis of mesoderm progenitor cells identifies HOPX as a novel regulator of hemogenic endothelium 0.21
Low-dose decitabine priming endows CAR T cells with enhanced and persistent anti-tumor potential by epigenetic reprogramming 0.15
The transcriptome of human endometrial mesenchymal stem cells under TGFβR inhibition reveals improved potential for cell-based therapies 0.09
Transcriptional Profiling of Werner Syndrome (WS) iPSC-derived MSC and the isogenic gene-edited controls 0.09
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 0.06
Genome wide impact of loss of mechanoluminal stimulation on neonatal intestine 0.06
Human ES Cell-derived Hepatoblasts are an Optimal Lineage Stage for HCV Infection 0.05
Altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency 0.05
Longitudinal transcriptome profiling of post-treatment Lyme disease syndrome 0.03
Aneuploidy triggers an immune response 0.03
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq] 0.01
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations 0.01


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