Gene Query: THADA

Dataset Description Geneva Score
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 69.4
RNA-sequencing of human liver tissue 23.97
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 21.47
RNA-dependent RNA polymerase sequence specificities of capsnatching viruses are tailored to aid viral replication 21.01
R430: A potent inbibitor of DNA and RNA viruses 19.57
BET bromodomain inhibitor iBET151 impedes human ILC2 activation and prevents experimental allergic lung inflammation 17.88
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 17.42
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes 15.44
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes (RNA-Seq) 15.44
Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells 14.88
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 13.87
Estrogen response in breast cancer cell line MCF-7 is dependent on NR2F2 [RNA-seq] 12.77
NR2F2 study 12.77
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 11.69
ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma 11.59
Effect of Influenza virus infection on lncRNA expression in A549 cells 10.85
NRDE2 negatively regulates nuclear exosome functions 10.73
Transcriptomics of human macrophages upon infection with Legionella pneumophila and two isogenic mutants, LamA and AnkH using RNA-seq 10.68
Viral determinants in H5N1 influenza A virus enable productive infection of HeLa cells 10.59
Transcriptome analysis of RANK-positive and RANK-negative luminal progenitor subpopulations in the human breast 10.32
NET-CAGE Characterizes the Dynamics and Topology of Human Transcribed Cis-regulatory Elements 9.83
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression 9.82
The ARID1A tumor suppressor controls global transcription via pausing of RNA Polymerase II 9.7
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma 9.66
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (RNA-Seq) 9.66
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 8.77
Transcriptome analysis of human airway epithelium infected by Human Bocavirus 1 8.75
Transcriptomic analysis of human tonsillar TFH subsets 8.7
Expression profiling of etoposide-induced senescent cells 8.58
MeRIP sequencing reveals angiogenic properties of vascular endothelial cells 8.54
Stably-paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor Triptolide 8.48
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 8.08
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation 7.92
IDH3a KO RNA-seq 7.91
Transcriptome analysis of total RNA in human osteosarcoma cell line U2OS before and after inhibition of zinc finger protein ZNF768 7.85
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer [RNA-Seq] 7.75
Modeling the ESR1 tyrosine 537 mutation with CRISPR-Cas9 for mechanistic studies and evaluation of therapeutic approaches for metastatic breast cancer 7.75
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 7.65
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 7.51
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 7.3
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 7.22
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 7.15
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 7.14
A sister of NANOG regulates genes expressed in pre-implantation human development 7.14
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 7.04
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 6.97
Transcriptional regulation of autophagy-lysosomal function in BRAF-driven melanoma progression and chemoresistance 6.85
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 6.83
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 6.82
RNA-seq in transgenic cells 6.78
Identification and validation of differentially expressed transcripts by RNA-Sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis 6.66
Expression profile and potential functions of circulating long noncoding RNAs in acute ischemic stroke in the Southern Chinese Han population 6.61
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 6.51
Effect of digoxin treatment on the gene and alternative splice expression in human pluripotent stem cells- derived mesenchymal stem cells 6.48
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 6.46
Molecular Hallmarks of Experimentally Acquired Immunity to Malaria [Pilot Study] 6.46
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation (RNA-Seq) 6.45
Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation 6.45
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 6.44
Response of HEK293 Freestyle cells to 36 h of culture in Zn(II)-depleted Freestyle medium 6.42
RNA-sequencing of isogenic primary, pre-malignant immortalized, and Ras-transformed human mammary epithelial cells 6.36
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 6.33
Gene expression changes caused by KRAS in MCF-10A 6.29
Evidence for rRNA 2'-O-methylation plasticity: control of intrinsic translational capabilities of human ribosomes 6.28
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 6.24
High throughput characterization of the m6A demethylase FTO by CLIP and RNAseq 6.23
Oncogenic MYC induces a dependency on the spliceosome in human cancer 6.22
Poly(ADP-ribosyl)ation dependent changes in CTCF-chromatin binding and gene expression in breast cells 6.22
Sorted MDMs with RFP+GFP+ or RFP+GFP- Mtb 6.21
Identification of transcription start sites for human A549 cell line using ReCappable-seq 6.18
High-Throughput Kinetic Analysis of Fractional Killing 6.14
RNASeq of Healthy Human Skin Tregs and CD4 Teffs versus Psoriatic Human Skin Tregs and CD4 Teffs 6.02
Whole Transcriptomic Sequencing of Metastatic Castration Resistant Prostate Cancer Samples 5.97
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 5.93
RNAseq Study in CC-671 Treated Cal-51 Cells 5.92
Profiling of lung tumor-infiltrating CD8 T cells according to their expression status of CD39 5.89
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 5.87
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 5.87
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 5.84
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 5.81
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 5.76
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 5.73
The stress granule transcriptome reveals principles of mRNA accumulation in stress granules. 5.7
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 5.68
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 5.68
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 5.65
Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. 5.65
Osteogenic programming of adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the Polycomb protein EZH2 5.63
High-throughput sequencing of PROMPT-enriched samples. 5.63
Targeted enhancer activation by a subunit of the integrator complex 5.62
Impact of dieldrin on transcription in Jurkat T cells 5.62
Expression analysis of Mebendazole treated THP-1 cells in three paired samples 5.6
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations [RNA-Seq] 5.57
DDX3X regulation of global translation is impaired by medulloblastoma-associated mutations 5.57
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia 5.56
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 5.55
Knockdown of ADNP in HCT116 colon cancer cells 5.5
RNA-seq analysis of the role of HBO1 (KAT7/MYST2) in the ovarian cancer cell line UWB1.289. 5.47
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 5.44
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 5.44
Splicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing 5.42
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 5.41
6mer seed toxicity in tumour suppressive microRNAs 5.37
The BCL6 RD2 domain governs commitment of activated B-cells to form germinal centers 5.37
RNAseq Analysis in glioblastoma cells treated with Mepazine 5.36
Effect of Hotair overexpression in human breast cancer cell lines 5.35
hTERT promotes cell adhesion and migration independent of telomerase activity 5.3
Transcriptome of EMT induced MCF10A cells by TGFb treatment or SNAIL S6A expression. 5.25
RNA-seq of YB5 cells treated with Proscillaridin A 5.24
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 5.22
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 5.21
Codon usage optimization in pluripotent embryonic stem cells [RNA-seq] 5.2
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 5.2
MicroRNA-125a-5p overexpression in human macrophages 5.19
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 5.16
Microprocessor mediates transcription termination in long noncoding microRNA genes 5.14
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 5.13
Identification of miRNA signatures during the differentiation of hESCs into retinal pigment epithelial cells 5.12
Single Cell RNA-Sequencing Identifies Diverse Roles of Epithelial Cells in Idiopathic Pulmonary Fibrosis 5.11
Gene expression alterations associated with acquired-resistance to the CDK4/6 inhibitor palbociclib [Palbociclib resistance_RNASeq] 5.07
RNA-seq analysis of control and CDK12-depleted ovarian cancer cells 5.03
TGF-β regulation of miRNA expression in pancreatic cancer 5.01
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 4.99
4sUDRB-seq: measuring transcription elongation and initiation genomewide 4.98
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 4.98
RNA-sequencing in irradiated and normal A549 cells. 4.97
Effect of BB608 on Gene Expression in HNSCC Cell Line 4.97
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 4.97
MYC dependent mRNA translation shapes gene expression and cell biology 4.95
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 4.93
Transcriptome analysis upon C6orf203 silencing 4.91
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 4.89
Gene expression changes upon drug withdrawal (Mel888 cell line) 4.88
Effect of FGF13 depletion on the H460 cell line 4.85
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC [Total RNA-Seq] 4.84
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC 4.84
Impact of HypERrlnc Knockdown on the human pericyte transcriptome 4.83
Developmental origins define epigenomic differences between subcutaneous and visceral adipocytes 4.79
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 4.79
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 4.77
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 4.76
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 4.76
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 4.71
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 4.7
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 4.7
Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells 4.69
Differentially expressed genes from RNA-Seq and functional enrichment results are affected by the choice of single-end versus paired-end reads and stranded versus non-stranded protocols 4.67
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 4.66
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 4.66
Ribosome profiling of TGFb-treated cells indicates reduced leucine availability 4.64
Vitamin C Promotes Apoptosis in Breast Cancer Cells by Increasing TRAIL Expression 4.59
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 4.59
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 4.57
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 4.57
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 4.57
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 4.48
Gene expression profile in breast cancer cells 4.48
Identification of ZEB1-regulated gene expression changes in HCC827 human lung adenocarcinoma cells 4.48
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 4.45
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 4.45
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 4.45
A TGFbeta-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression 4.44
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 4.44
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 4.42
Identification of Sin3B regulated genes during quiescence 4.42
A role for ZNF598 in post-transcriptional gene regulation 4.38
METTL3 promotes translation in human cancer cells 4.38
Mesenchymal stem/stromal cell engulfment reveals metastatic advantage in breast cancer 4.37
Isolation and Transcriptome Analyses of Human Erythroid Progenitors: BFU-E and CFU-E 4.36
A Brain Penetrant Mutant IDH1 Inhibitor Provides In Vivo Survival Benefit 4.36
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 4.33
RNA-sequencing 4.32
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 4.31
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 4.29
Subcellular RNA fractions of HSV-1 infected primary human fibroblasts 4.29
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 4.27
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 4.27
SLIGRL-induced gene expression changes in NHEK cells 4.23
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 4.22
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 4.21
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 4.19
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 4.17
RNA-seq during MCF10A-ER-Src cell transformation and upon factor knockdowns 4.17
Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation 4.17
IQGAP3 interacts with Rad17 to activate the MRN/ATM/Chk2 signaling and promote radioresistance in lung cancer 4.14
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 4.13
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 4.13
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 4.13
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 4.1
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 4.09
EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC 4.09
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 4.08
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 4.08
Genome-wide view of the impact of Spt5-Pol II inhibitors (SPIs) on mRNA levels [RNA-Seq 2h] 4.07
SETDB2 links E2A-PBX1 to cell cycle dysregulation in acute leukemia through CDKN2C repression [sequencing] 4.07
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 4.07
Epigenetic reprogramming of melanoma cells by vitamin C treatment 4.05
BCL11B 4.04
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 4.03
Landscape of H3K4me3 in human CD19 cells 4.02
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer 4.01
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer [RNA-seq] 4.01
Downregulation of LATS kinases alters p53 to promote cell migration 4.01
H3K27Ac in MCF7 Y537S ER mutant cells and RNAseq with and without treatment with THZ1 4.01
Plasma cell mitochondrial pyruvate import controls the duration of humoral immunity. 4.0
Expression and functions of long noncoding RNAs during human T helper cell differentiation 3.98
RNA-seq differential expression studies: more sequence, or more replication? 3.98
RNA editing in nascent RNA affects pre-mRNA splicing 3.98
Effect of CHKA knockdown on C4-2 cell transcriptome 3.98
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation 3.96
Global Mapping of Human RNA-RNA Interactions 3.96
Activation of a SOX2-dependent transcriptional regulatory circuit drives glioblastoma. 3.95
NAPRT activation of macrophages 3.93
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 3.92
Integrative Genomic and Transcriptomic Analysis Identified Candidate Genes Implicated in the Pathogenesis of Hepatosplenic T-cell Lymphoma 3.89
Hepatosplenic T cell lymphoma 3.89
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 3.85
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 3.85
Transcriptomic profiling of O-GlcNAcylated mRNA-protein complexes by using OG-CLAP in HeLa cells. 3.83
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 3.8
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 3.8
Circular RNA profiling reveals the different distribution/characteristic and possible transport mechanism among the subcellular fractions 3.8
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 3.78
RNA seq_A375 gSMARCB1 + A549 etoposide, Aurora kinases inhibitors treated 3.76
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 3.73
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 3.72
Development of an In Vitro Human Liver System for Interrogating Non-Alcoholic Steatohepatitis 3.71
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 3.7
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 3.68
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 3.68
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 3.67
ETV7 and interferon response 3.67
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 3.67
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 3.67
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 3.65
Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma 3.61
Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation 3.58
RNA-sequencing of formalin fixed human primary melanoma tissue 3.58
Cellular recruitment by podocyte-derived pro-migratory factors in assembly of the human renal filter 3.57
PRDM1 inhibits proliferation of human colon cancer organoids 3.57
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 3.55
Intron retention induced by microsatellite expansions as a disease biomarker. 3.54
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 3.51
RNA isoform screens reveal the essentiality and tumor suppressor activity of ultraconserved poison exons 3.48
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines [RNA-seq] 3.46
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines 3.46
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 3.45
DNA Methylation Reprograms Metabolic Gene Expression in End-Stage Human Heart Failure 3.43
RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells. 3.43
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 3.42
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 3.42
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 3.42
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 3.32
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 3.32
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 3.28
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 3.27
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 3.27
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 3.26
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing 3.25
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing [RNA-Seq] 3.25
Novel Targeting of Transcription and Metabolism in Glioblastoma 3.22
The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains 3.17
Recovery and analysis of nascent RNA 3.17
m6A-RNA mapping, SND1-RNA binding profile mapping and SND1-depletion in KSHV-infected B-lymphocytes 3.15
DAOY-Notch1/Notch2 knockout: transcriptome comparison 3.11
Transcriptome sequencing wide functional analysis of human mesenchymal stem cells 3.07
The RNA helicase DDX39B regulates IL7R alternative splicing reducing the risk of Multiple Sclerosis 3.04
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 3.04
Transcriptomes of human monocytes from patients with familial hypercholesterolemia before and after statin treatment 2.98
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 2.95
Transcriptomes of human monocytes and monocyte-derived macrophages with or without glucocorticoid treatment 2.92
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 2.91
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 2.9
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 2.9
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 2.87
Widespread backtracking by RNA pol II is a major effector of gene activation, 5’ pause release, termination and transcription elongation rate 2.85
Histone deacetylase inhibition enhances antimicrobial peptide but not inflammatory cytokine expression upon bacterial challenge 2.85
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 2.83
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence 2.82
RNA-Seq profiling in PBMCs and spinal cord from ALS patients and healthy controls 2.8
Comprehensive RNA-Seq profiling in PBMCs of ALS patients and healthy controls 2.8
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 2.79
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 2.73
The Polycomb protein BMI1 induces an invasive gene expression signature in melanoma that promotes metastasis and chemoresistance. 2.72
Gene expression signatures of innate lymphoid cells from human blood 2.71
RNA-Sequencing experiment for effects of PKF115-584 treatment on four T-ALL cell lines (RPMI8402, HPB-ALL, Jurkat, CCRF-CEM). 2.7
LIN28A Over-expression RNAseq 2.67
mRNA expression in human DAOY cells 2.67
Integrative classification of human coding and non-coding genes based on RNA metabolism profiles 2.67
Identification of PRMT5-dependent genes in ESA+CD24lowCD44+ MCF7 cells 2.6
Widespread intronic polyadenylation diversifies immune cell transcriptomes 2.58
Single-cell expression profiling reveals new roles for G-protein-coupled receptors in the regulation of Th17 pathogenicity 2.58
Genome-wide expression profiling of B Lymphocytes reveals IL4R increase in allergic asthma 2.57
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 2.55
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 2.55
p53 activity results in DNA replication fork processivity 2.53
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 2.52
Non-transmissible measles virus vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells 2.49
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 2.49
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [Primary RNA-Seq] 2.48
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 2.47
YAP and MRTF-A, transcriptional co-activators of RhoA- mediated gene expression, are critical for glioblastoma tumorigenicity 2.46
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 2.46
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 2.43
Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects 2.41
Effect of PRDM11 depletion in U2932 cells 2.41
A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (RNA-Seq) 2.39
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 2.38
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 2.35
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 2.33
Gene expression profiling in follicular lymphoma (FL) samples and paired transformed follicular lymphoma (tFL) (n=6 samples) 2.32
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. 2.32
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 2.28
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export II 2.28
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 2.27
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 2.27
RNA-sequencing of the human milk fat layer during colostrum, transitional, and mature stages of lactation 2.27
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 2.26
Exploring transcriptomic landscapes in red cell populations, in their extracellular vesicles and on single cell level 2.26
Transcriptome profiling of H1-iCas9 cells grown on laminin and on MEFs 2.26
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 2.25
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 2.21
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 2.2
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 2.2
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 2.19
NF-κB p65 dimerization and DNA-binding is important for inflammatory gene expression 2.19
RNA-Seq in PWS iPSC-derived neurons 2.13
Sequence dependency and regulatory function of dimeric NOTCH1/RBPJ complexes on coding and non-coding transcription in T-lymphoblastic leukemia 2.12
Next Generation Sequencing upon siRNA-mediated knockdown of DRAIC in MCF-7 cells. 2.12
Monitoring Nivolumab binding as a method to clarify the residual therapeutic effects and to characterize the immune profile in antibody bound T cells in previously treated non-small cell lung cancer patients 2.12
The Regulation of IFN Type I Pathway Related Genes RSAD2 and ETV7 Specifically Indicate Antibody-Mediated Rejection After Kidney Transplantation 2.09
Thyroid State Regulates Gene Expression in Human Whole Blood Cells 2.08
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 2.06
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 2.06
Aberrant expression profile of lncRNA and mRNA in dilated cardiomyopathy by RNA-sequence 2.04
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 2.03
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 2.02
Cajal bodies are linked to genome conformation [RNA-Seq] 1.96
Cajal bodies are linked to genome conformation 1.96
Self-associated molecular patterns mediate cancer immune evasion by engagement of Siglec receptors 1.96
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 1.93
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 1.91
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 1.91
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 1.89
Human interleukin-4 treated regulatory macrophages promote epithelial wound healing and reduce colitis in an mouse model 1.87
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 1) 1.85
Energy Metabolism during Anchorage-Independence 1.78
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 1.76
Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells 1.75
Real-time observation of light-controlled transcription in living cells 1.72
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (scRNA-Seq) 1.72
Determination of tRNA aminoacylation levels by high throughput sequencing 1.71
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 1.69
Unbiased evaluation of cell-free amniotic fluid transcriptome of term and preterm infants to detect fetal maturity 1.67
Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy 1.66
Single-cell RNA-seq reveals differentiation of bona fide human pDCs and cDC1s in cultures of cord blood CD34+ progenitors, and a newly identified terminal differentiation step of cDC1s 1.65
RNA-seq of Human neck of femur (NOF) fracture hip and osteoarthritic (OA) cartilage 1.64
Long noncoding RNA ROCR contributes to SOX9 expression and chondrogenic differentiation of human mesenchymal stem cells 1.64
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 1.64
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 1.64
Characterization of human ILC2 subsets 1.63
Circular RNA expression signature of low-glucose-treated MIA PaCa-2 cells 1.58
Noncoding regions are the main source of targetable tumor-specific antigens 1.56
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 1.55
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 1.47
Osmostress induced changes of chromatin architecture and transcription in mammalian cells [RNA-Seq, HiC] 1.44
Osmostress induced changes of chromatin architecture and transcription in mammalian cells 1.44
Anti-inflammatory effect of indoleacrylic acid (IA) 1.44
Frailty in middle age is associated with race-specific changes to the transcriptome. 1.42
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 1.4
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] 1.4
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. [RNA-Seq] 1.39
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. 1.39
Identification of a LIF-responsive replication-competent human β cell 1.39
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 1.39
Evolutionary origin and functional divergence of stem cell homeobox genes in eutherian mammals 1.38
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 1.36
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 1.36
Regulatory network controlling tumor-promoting inflammation in human cancers [RNA-seq] 1.35
Regulatory network controlling tumor-promoting inflammation in human cancers 1.35
Transcriptome analysis of BAP1 knockout and restoration 1.3
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 1.3
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 1.27
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 1.26
Human Treg IFNg/IL-10 subpopulations 1.26
Hypoxic transcriptome of SQ20B human head and neck cancer cells 1.23
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 1.23
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 1.23
Genome-wide mapping of TEL-AML1 targets in acute leukemia 1.21
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 1.19
An optimization system for isolating and sequencing of single human colon cancer cells 1.19
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 1.16
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 1.16
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 1.14
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 1.14
Transcriptome profiling identified a 3-lncRNA regulatory network in transthyretin against glucose induced hRECs dysfunction 1.12
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 1.1
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 1.1
Transcriptome profiling of A2M treated A549 Cell Line Samples 1.1
Genomic deletion of malic enzyme 2 confers collateral lethality in pancreas cancer 1.08
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 1.04
RNA-Seq of SLNCR1 over-expression in the melanoma cell line A375 1.04
Sequencing of freshly produced RNA following exposure of cells to DNA damage-inducing UV mimetic 4-hydroxyaminoquinolone (4-NQO) 1.03
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 1.02
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 1.02
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq) 1.01
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles 1.01
Generation and persistence of human tissue-resident memory T cells in lung transplantation 1.0
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 1.0
RNAseq of CD8+ and CD8- MAIT cells in human peripheral blood 0.98
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 0.98
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis 0.98
Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains 0.96
Dual RNA-seq – High-resolution comparative Dual RNA-seq time-course 0.96
Low H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas 0.96
Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1 0.93
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 0.93
ChIPseq and RNAseq analysis of T47D cells with/without silencing TRPS1/CHD4 0.9
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 0.86
TALEN-based knockout of mir-141 and mir-200c in SK-BR-3 cells 0.84
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 0.84
RNA-seq of primary patient AML samples 0.84
Transposon-based construction of strand-specific RNA-seq libraries 0.81
mRNA expression profile of Lymphocytes by high-throuput sequencing 0.79
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 0.76
CT Irradiation Induced Changes of Gene Expression within Peripheral Blood Cells 0.76
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 0.75
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 0.75
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 0.73
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 0.72
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 0.72
RNA seq with AML (NB4) cells upon FTO inhibition 0.71
Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and Natural Killer Cell Function 0.71
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 0.7
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 0.69
Genes encoding cognate receptors for IRI-related recipient cytokines are expressed in donor livers 0.69
Nascent RNA Sequencing after NMYC activation in SH-EP MYCNER cells 0.67
Measuring the effect of MYC on transcription during the DNA double-strand break response by RNA-seq of newly synthesized transcripts 0.66
Alterations of the MEK/ERK, BMP, and Wnt/b-catenin pathways detected in the blood of individuals with lymphatic malformations 0.64
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 0.64
RNA-Seq of CD4+ T cells treated with AS1842856 or DMSO 0.62
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.61
Next Generation Sequencing Facilitates Quantitative Analysis of UVB(20mJ/cm2 and 40mJ/cm2) exposed and untreated HaCaT keratinocytes Transcriptomes 0.6
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 0.58
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 0.58
Effects of plasticizers (bisphenol A, bisphenol AF) and an herbicide in MCF7 human breast cancer cells 0.56
Transcriptional changes after overexpression of proliferation drivers in human mammary epithelial cells. 0.56
Identification of Resistance Genes to BRAF Inhibitor in Melanoma by piggyBac Transposon Activation Mutagenesis Screen 0.54
Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer 0.51
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 0.5
RNA expression profiles from HUVECs overexpressing adenovirally delivered HIF1a and HIF2a proteins 0.5
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) [RNA-seq] 0.49
Epigenetic changes induced by Bacteroides fragilis toxin (BFT) 0.49
Mesothelioma xenografts in nude mice: PBS treated versus pirfenidone treated 0.48
Effect of OVO-like 1 knockdown on global transcript expression in differentiated BeWo trophoblast cells 0.47
Unbiased identification of trans regulators of ADAR and A-to-I RNA editing 0.46
Identification of trans regulators of ADAR and A-to-I RNA editing using RNA-seq 0.46
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma 0.44
Targetting super enhancer associated oncogenes in esophageal squamous cell carcinoma [RNA-seq] 0.44
Function and hormonal regulation of GATA3 in human first trimester placentation 0.44
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.42
Oncogenic roles of ARID5B in T-ALL 0.4
RNA-seq analysis in knockdown Jurkat samples for each factor of TAL1 complex 0.4
MCF-7 as a model for functional analysis of breast cancer risk variants 0.39
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation 0.38
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 0.38
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 0.38
Positively selected enhancer elements endow tumor cells with metastatic competence 0.36
Gene expression changes due to PARP knockdown in human cells 0.35
Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements 0.29
Characterisation of the EZH2 regulated transcriptome in de novo transformed cells (RNA-Seq) 0.29
RNA sequencing data of whole blood cells of normal glucose tolerant (NGT) and gestational diabetes (GDM) pregnant women 0.29
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk 0.28
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk [RNA-seq] 0.28
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease 0.28
Pre-clinical evaluation of cysteamine bitartrate as a therapeutic agent for mitochondrial respiratory chain disease (human) 0.28
An evolutionary recent IFN-IL-6-CEBP axis is linked to monocyte expansion and tuberculosis severity in humans. 0.27
Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes 0.26
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.26
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.26
Modulation of nonsense-mediated decay by rapamycin 0.26
Transcriptomics profiling of CD141+ dendritic cells isolated from peripheral blood or synovial fluid of arthritis patients 0.25
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 0.23
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 0.21
Pro-angiogenic Ginsenoside F1 and Rh1 Inhibit Vascular Leakage by Modulating NR4A1 0.19
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex 0.19
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex (Gro-seq) 0.19
Stapled peptide inhibitors of RAB25 target context-specific phenotypes in cancer 0.15
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 0.13
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 0.13
Widespread Transcription beyond mRNA 3’ Ends Yields Abundant Regulatory RNAs 0.12
single cell RNA-seq from GM12878 (ENCSR673UIY) 0.1
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 0.1
The Wnt/β-catenin-signaling pathway is modulated by androgen ablation therapy for advanced clinical prostate cancer and contributes to androgen independent cell growth 0.09
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 0.06
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 0.06
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 0.05
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 0.04
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 0.02
The Small Molecule ISRIB Reverses the Effects of eIF2α Phosphorylation on Translation and Stress Granule Assembly 0.01


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