Gene Query: TMEM59L

Dataset Description Geneva Score
The Polycomb protein BMI1 induces an invasive gene expression signature in melanoma that promotes metastasis and chemoresistance. 113.83
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 39.74
Hydrogel scaffolds promote neural gene expression and structural reorganization in human astrocyte cultures 28.88
Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence 27.52
RNA sequencing for PDX1, NGN3 and MAFA transduced iPSCs cell 24.71
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data 22.51
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 21.48
The m 6 A-methylase complex recruits TREX and regulates mRNA export. 20.73
Transcriptome analysis of human reninomas as an approach to understanding juxtaglomerular cell biology 19.56
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 18.49
A peninsular structure coordinates asynchronous differentiation with morphogenesis to generate pancreatic islets [bulk vs buds] 18.41
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 18.24
Comparing gene expression in iPSC derived RPE from control and AMD donors 18.24
RNA helicase A is necessary for KIF1Bβ tumor suppression in neuroblastoma 18.09
Genome-wide functional assessment of enhancer activities in the human genome 17.74
Quantitative comparison between cellular mRNAs and exosomal mRNAs in human iPSC-derived motor neurons 17.49
circRNA-sequencing 16.97
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 16.87
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 16.87
Robust generation of honemogeneous midbrain organoids with in vivo–like cellular composition facilitates neurotoxin-based Parkinson’s disease modeling 16.59
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 16.03
Hyper-excitability of Neurons generated from Patients with Bipolar Disorder 15.42
ZNF804A transcriptome networks in differentiating human neurons derived from induced pluripotent stem cells 14.9
CDK4/6 inhibitor resistance in prostate cancer 14.42
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 14.12
Co-regulation of splicing by Rbfox1 and hnRNP M 13.87
Co-regulation of splicing by Rbfox1 and hnRNP M [hnRNPM k-d+Rbfox1 RNA-Seq] 13.87
Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21 13.87
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 13.49
Rna-seq transcriptome data for insulin-GFP+ cells differentiated from NEUROD1 knock out and NEUROD1+/+ control human embryonic stem cells. 13.21
NEUROD1 dependent gene regulation in murine pancreatic endocrine cells and human stem cell derived insulin producing cells 13.21
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells [RNA-seq] 13.14
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells 13.14
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability [RNA-Seq] 12.83
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability 12.83
AR-independent prostate cancer is sustained through FGF signaling 12.76
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 12.42
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes 12.34
Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes [RNA-Seq] 12.34
Synaptic dysfunction in human neurons with Autism associated deletions in PTCHD1-AS 12.06
Examining serotonergic neuron differentiation from human iPSCs 11.84
Repurposing of promoters and enhancers during mammalian evolution 11.61
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 11.54
Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain 11.17
Analysis of the Clustered Protocadherin (cPcdh) Locus in Human Pluripotent Stem and Derived Cells [RNA-seq II our of II] 11.09
Early transcriptome profiling of microRNA-mediated neuronal reprogramming [RNA-seq timecourse] 10.88
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 10.86
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L 10.74
Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons 10.57
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression 10.5
Transcriptional dependencies in diffuse intrinsic pontine glioma 10.46
Discovery of cis-spliced chimeric RNAs between adjacent genes in human prostate cells 9.9
Transcriptional profiling of microglia; current state of the art and future perspectives 9.72
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 9.71
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 9.71
Disruption of GRIN2B impairs differentiation in human neurons 9.64
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 9.57
Analyzing the interactions of mRNAs, miRNAs, lncRNAs and circRNAs to predict competing endogenous RNA networks in glioblastoma 9.48
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 9.25
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 9.25
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 9.07
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 9.07
Whole transcriptome RNA sequencing of human cells after HCV infection (ML-1 thyroid cell line, primary thyrocytes and Huh7.5 hepatocyte cell line) 9.02
Transcriptome profile of HepG2-expressing ATP7B-H1069Q (liver hepatocellular cells) exposed to JNK or p38 Inhibitor 8.89
Generation of Brain Region-specific Organoids using a Miniaturized Spinning Bioreactor and Modelling ZIKV Exposure 8.87
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 8.74
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 8.74
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer [RNA-Seq] 8.67
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer 8.67
GREB1, a novel target of Wnt signaling, promotes development of hepatoblastoma by suppressing TGFβ signaling 8.65
In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells 8.33
Functional astrocytes differentiated from hiPSCs 8.13
Restoration of Progranulin Expression Rescues Cortical Neuron Generation in Induced Pluripotent Stem Cell Model of Frontotemporal Dementia 8.02
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 7.42
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 7.12
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 7.04
Gene Expression Profiling of WT and KDM3A Knocked out Cell 7.04
A single-cell atlas of the human cortex reveals drivers of transcriptional changes in Alzheimer’s disease in specific cell subpopulations 6.99
Epigenomic landscape during organ formation in human early embryos 6.91
Novel Targeting of Transcription and Metabolism in Glioblastoma 6.88
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas [Human RNA-Seq] 6.88
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas 6.88
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 6.84
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 6.84
Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration 6.73
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing 6.71
EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling 6.35
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 6.33
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 6.28
Chromatin landscape of human visceral and subcutaneous adipocytes 6.24
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 6.23
Lung Cancer Cell-Mediated Skeletal Muscle Mitochondrial Dysfunction is Mitigated by 1a,25-Dihydroxyvitamin D3 6.22
Analysis by Whole Transcriptome Sequencing of the Effects of LLC1 conditioned medium, LLC1 conditioned plus Calcitriol, non-conditioned medium, and non-conditioned medium plus Calcitriol on mRNA Expression in Primary Human Skeletal Muscle Cells 6.22
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 6.13
Receptor tyrosine kinase signaling promotes post-embryonic morphogenesis and survival of glia and neural progenitor cells 6.11
Universal alternative splicing of noncoding exons 6.08
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 6.07
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 5.81
The Glioma-Infiltrating T Cell Receptor Repertoire 5.76
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 5.73
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 5.73
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 5.57
Dynamic epigenetic remodeling underlies microRNA-mediated transdifferentiation of human adult fibroblasts into neuronal subtypes 5.56
Transcriptomic analysis of trametinib-resistant HCT116 colorectal carcinoma cells compared to the parental control cells 5.53
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 5.51
CUREfast: Accelerating research with families 5.42
Regionally specified human pluripotent stem cell-derived astrocytes 5.41
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq 5.4
Global transcriptional analysis and genome-wide analysis of chromatin state in extended pluripotent stem cells, primed pluripotent stem cells, and naïve pluripotent stem cells 5.4
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation 5.36
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network 5.35
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2 [RNA-seq] 5.35
Efficient derivation of microglia-like cells from human pluripotent stem cells 5.28
Regionally distinct astrocyte interferon signaling promotes blood-brain barrier integrity and limits immunopathology during neurotropic viral infection 5.27
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration [Microfluidics] 5.27
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 5.23
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 5.23
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 5.23
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition 5.16
Enhancer Domains in Gastrointestinal Stromal Tumor Regulate KIT Expression and are Targetable by BET Bromodomain Inhibition [RNA-seq] 5.16
TGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity 4.96
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 4.95
Non-coding regions are the main source of tumor-specific antigens 4.94
Non-coding regions are the main source of tumor-specific antigens [human] 4.94
Redifferentiation of expanded human islet β cells by inhibition of ARX 4.84
Transciptomic profiling of human fetal lung samples 4.8
RNA-Seq analysis of neurons derived from induced pluripotent stem cells reprogrammed from dental pulp 4.79
MYOD Gene Expression Regulation during Myogenic Conversion of Fibroblasts 4.78
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 4.75
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 4.71
RNA-sequencing WT vs SOCS3 knockout Glioblastoma stem-cells 4.68
RNA-seq in endometrial stromal tumors 4.68
RNA expression in primary huamn muscle cells treated with 1,25(OH)2D3 or vehicle 4.51
mRNA and miRNA expression in primary human muscle cells treated with 1,25(OH)2D3 or vehicle 4.51
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 4.51
Trans-differentiation of human adult peripheral blood T cells into neurons 4.5
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [HCT RNA-Seq] 4.27
FOXP2's impact on the primate transcriptome 4.27
Expression profile of GIST48 cells with siETV1 or siFOXF1 knockdown 4.23
FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST) 4.23
Anaylsis of the effect of down-regulation of the EWS-FLI1 fusion protein in Ewing Sarcoma cells by RNA-seq. 4.22
TGF-β promotes genomic instability after loss of RUNX3 4.21
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain 4.2
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain [RNA-Seq] 4.2
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 4.13
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 4.07
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 4.07
Re-Wiring 3D Nuclear Architecture by a Single Transcription Factor during Somatic Cell Reprogramming 4.01
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration [RNA-seq2] 4.0
Genome expression analysis of Lung Progenitors matured in the presence of constitutively active or pharmacologically inhibited Glycogen Synthase Kinase 3 4.0
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing (Total RNA sequencing) 3.97
Regulartory effect of HNRNPL and LARP on RNA expression in LNCaP prostate cancer cells 3.94
HNRNPL and its RNA Targets in Prostate Cancer 3.94
MYOD Remodeling of the Genome Architecture during Myogenic Conversion of Somatic Cells 3.92
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 3.9
Human embryonic stem cells in E8 and AKIT culture medium 3.89
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 3.89
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 3.89
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 [RNA-seq] 3.86
Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21 3.86
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 3.83
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [ribosome profiling] 3.75
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 3.68
RNA-Seq characterization of human H1-derived NPC differentiation timecourse 3.6
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 3.57
High-Throughput Drug Screening identifies Pazopanib and Clofilium tosylate as effective treatments for malignant rhabdoid tumors 3.57
Engineering Patient-Specific Tissue Implants 3.54
RNA sequencing for human induced pluripotent stem cell cardiomyocyte differentiation 3.54
Transcriptome analyses of human pancreatic islets and pseudoislets 3.52
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease 3.48
REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set) 3.48
single cell RNA-seq from Purkinje cell (ENCSR888LYA) 3.46
The transition from proliferation to quiescence in glioblastoma stem-like cells requires Ca2+ signaling and mitochondria remodeling 3.38
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (LNCaP RNA-seq) 3.36
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 3.35
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 3.29
Next Generation Sequencing Facilitates Quantitative Analysis of transcriptomes of human cord blood CD34+ cells treated with HDAC5 inhibitor 3.27
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 3.25
Elucidating the microRNA-203 specific biological processes in glioblastoma cells from comprehensive high-throughput RNA-sequencing transcriptome profiling 3.24
Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx 3.21
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [RNA-seq] 3.19
Rescue of Fragile X syndrome by DNA methylation editing of the FMR1 3.19
Kidney organoid reproducibility across multiple human iPSC lines and diminished off target cells after transplantation revealed by single cell transcriptomics 3.19
Detailed genomic and molecular characterization of Indian induced pluripotent stem cell lines 3.16
Inhibition of the Aryl Hydrocarbon Receptor - Polyamine Biosynthesis Axis Suppresses Multiple Myeloma and prostate cancer progression 3.15
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 3.14
Human iPSC-based Modeling of Late-Onset Disease using Progerin-induced Aging 3.11
Reduced CYFIP1 in human neural progenitors as 15q11.2 deletion model: donor specific dysregulation of schizophrenia/epilepsy genes 3.1
RNA-Seq of the corpus callosum from 12 individuals 3.07
Identification of the RB loss-induced transcriptome in prostate cancer [RNA] 3.06
Identification of the RB loss-induced transcriptome and E2F1 cistrome in prostate cancer 3.06
Transcriptome analysis of SH-SY5Y cells after knockdown of circSLC45A4 3.05
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS 3.04
Multiple sclerosis and EAE 3.03
Human optic chiasm from healthy controls and multiple sclerosis patients 3.03
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma [RNA-seq] 2.99
The SS18-SSX oncoprotein hijacks KDM2B-PRC1.1 to drive synovial sarcoma 2.99
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 2.98
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 2.98
Analysis of human, chimpanzee, macaque and mouse tissue transcriptomes using Next Generation Sequencing 2.98
Transcriptome of invasive mucinous adnocarcinoma of the lung and adjacent normal lung tissues from 6 patients based on RNA-seq method 2.97
High-efficiency RNA-based reprogramming of human primary fibroblasts 2.92
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B 2.86
Total RNAseq of human putamen and caudate nucleus tissues in healthy control and Bipolar Disorder individuals 2.86
Dual modulation of neuron specific microRNAs and the REST complex promotes functional maturation of induced human adult neurons 2.86
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 2.84
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 2.82
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations 2.8
Mechanism suppressing H3K9 trimethylation in pluripotent stem cells and its demise by polyQ-expanded huntingtin mutations [RNA-seq] 2.8
Necroptosis inhibition protects from dopaminergic neuronal cell death in OPA1 mutant Parkinson’s disease patient neurons and MPTP treated mice 2.74
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 2.72
Capturing the biology of mild versus severe disease in a pluripotent stem cell-based model of Familial Dysautonomia 2.72
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 2.71
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 2.71
Functional role of SLIT2 and ROBO1 in trophoblasts 2.66
FGF2 regulation of gene expression in stable inducible Neurons 2.65
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas 2.64
c-Jun promotes cell migration and drives expression of the motility factor ENPP2 in soft tissue sarcomas [RNA-Seq] 2.64
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [d7+d14] 2.6
Verification and rectification of cell type-specific splicing of a Seckel syndrome-associated ATR mutation using iPS cell model 2.59
Integration of genome-wide DNA methylome and transcriptome of human intestinal fibroblasts reveals novel candidate gene signatures in Crohn’s disease-associated fibrosis 2.58
Next Generation Sequencing Facilitates Quantitative Analysis of human patient derived primary Glioblastoma (GBM) cancer cell Transcriptomes 2.57
Total RNA sequencing of APC mutant and wt colonic organoids 2.53
Targeted reactivation of FMR1 transcription in FXS embryonic stem cells 2.52
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 2.51
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 2.51
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 2.49
Non-coding and coding transcriptional profiles are significantly altered in pediatric Retinoblastoma tumors 2.47
Effects of Belinostat and Dexamethasone treatment of A549 gene expression 2.45
Iron response of HepG2 cells 2.43
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 2.43
Persistence of stem cell metabolism in cancers as a failure of differentiation 2.34
Human Long Intergenic Noncoding RNA Linc-ADAL Knockdown in Mature Adipocytes using Lentiviral ShRNA 2.32
NKX2.2 2.3
RNA-Seq analysis of NKX2.2 knockdown in human pancreatic islets 2.3
Transcriptome profiling of HepG2 cells upon treatment of the menin-MLL inhibitor MI-503 or DMSO 2.29
High throughput analysis of three human adipose cell lines PAZ6, SGBS and SW872 2.28
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration 2.28
RNA Missplicing in Fuchs Endothelial Corneal Dystrophy 2.26
Total RNA sequencing of WT intestinal orgaonids. 2.24
Identification of differential expressed genes of JQ1 or JQ1+Bortezomib in colorectal cancer cells 2.24
Gene expression regulated by CSA and CSB in neuroblastoma cell line 2.19
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 2.15
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 2.13
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 2.13
Epigenetic Inactivation of Cysteine Dioxygenase Type 1 Contributes to ROS-dependent Progression of Colorectal Cancer 2.11
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 2.09
Gene expression changes after LOC550643 silencing 2.08
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 2.04
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 2.04
HNF1A deficiency impairs β-cell fate, granule maturation and function 2.03
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 2.01
Lysine benzoylation is a novel histone mark [RNA-seq] 1.98
Lysine benzoylation is a novel histone mark 1.98
Gene expression analysis of human haploid cells (HAP1) depleted of SMARCB1 and SMARCA4 1.92
Evidence for HOXC6 as a potential molecular marker for non-small cell lung cancer 1.91
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug 1.91
Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug [human] 1.91
FOXP1 orchestration of ASD-relevant signaling pathways. 1.89
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 1.87
RNA-Sequencing of HepG2 cells treated with TGFBeta 1.86
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 1.84
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 1.84
Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq) 1.8
Genome-wide chromatin analysis of Ewing sarcoma 1.8
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung [RNA-seq] 1.79
Super-enhancer-driven CCAT1 is co-activated by SOX2 and TP63 and promotes squamous cancer from esophagus, head and neck and lung 1.79
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival 1.78
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival [RNA-Seq] 1.78
SIX4 acts as a master regulator of genes associated with the malignant phenotype of non-small cell lung cancer cells 1.77
Identification of Resistance Genes to BRAF Inhibitor in Melanoma by piggyBac Transposon Activation Mutagenesis Screen 1.76
RNA-seq of human fibroblasts after irradiation 1.76
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [cPDS-RNA-seq] 1.74
Directed differentiation of human embryonic stem cells to corneal endothelial cell-like cells: A transcriptomic analysis 1.72
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 1.72
RNAseq in Alzheimer's Disease patients 1.71
iPSC-Derived Cholangiocytes 1.69
Metabolism as an early predictor of DPSCs aging 1.69
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability 1.69
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability [RNA-seq] 1.69
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 1.66
Tracking distinct RNA populations using efficient and reversible covalent chemistry 1.65
iPSC derived motor neuron cultures from C9ORF72 carriers 1.64
Analysis of Combined Transcriptomes Identifies Gene Modules Differentially Responding to Pathogenic Stimulation in Vascular Smooth Muscle and Endothelial Cells 1.64
Zika virus directly infects human peripheral neurons and induces cell death 1.63
RNA-seq analysis of RALD iPSCs after in vitro differentiation 1.63
Impeding transcription of expanded microsatellite repeats by deactivated Cas9 1.61
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 1.58
In vitro differentiation of human embryonic stem cells into ovarian follicle-like cells 1.57
Spatial proximity to fibroblasts impacts molecular features and therapeutic sensitivity of breast cancer cells influencing clinical outcomes 1.55
Exploring ILF2 regulatory genes by next-generation sequencing 1.55
Differetially expressed genes after hTR overexpression in U2OS cells 1.49
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 1.49
ENCODE Cold Spring Harbor Labs Long RNA-seq 1.49
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 1.48
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 1.48
BioProject PRJNA381064: Convergent origination of a Drosophila-like dosage compensation mechanism in a reptile lineage (Gene expression profiling in several tetrapod species, bulk tissue RNA-seq) 1.47
Differentiation enhances Zika virus infection in neuronal brain cells 1.46
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 1.46
Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance 1.44
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 1.44
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons 1.42
Generation of mature lung alveolar epithelial cells from human pluripotent stem cells 1.42
ARID1A and ARID1B loss in HCT116 and TOV21G cells 1.41
BMS-470539 on human synovial fibroblasts 1.4
Increased Neanderthal ancestry in genomic regions associated with lipid catabolism in contemporary Europeans 1.37
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 1.37
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 1.35
The effect of insulin on mRNA transcription of human pluripotent stem cells 1.34
Cellular response to hepatitis E virus (HEV) infection 1.34
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 1.33
Identification of Sin3B regulated genes during quiescence 1.32
Transcriptome analysis of diverse cell types infected with human cytomegalovirus [RNA-Seq] 1.3
A SIRT1-centered Circuitry Regulates Breast Cancer Stemness and Metastasis 1.3
LncRNA DEANR1 facilitates human endoderm differentiation by activating FOXA2 expression 1.29
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells [RNA-seq] 1.28
Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells 1.28
Comprehensive Transcriptome Analysis of Cerebral Cavernous Malformation Across Multiple Species and Genotypes 1.27
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration 1.27
Identification of a LIF-responsive replication-competent human β cell 1.26
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived neurons 1.24
Single Cell Analysis Reveals Unexpected Transcriptional Heterogeneity of Neural Progenitors in the Developing Human Cortex 1.24
Effect of CHKA knockdown on C4-2 cell transcriptome 1.24
Gene expression profiling of iPSC-derived cardiomyocytes with BAG3 mutations 1.22
Transcriptome analysis of human embryonic stem cells (hESCs) upon siRNA-mediated knockdown of hESC-essential genes 1.22
PRRX2 and HEY2 double knock-down facilitates ASCL1-induced neuron conversion in human dermal fibroblasts. 1.22
Effect of hyper-and hypoactivation of Notch signaling in IL-4-stimulate THP-1 1.18
Allosteric Antagonist Modulation of TRPV2 by Piperlongumine Impairs Glioblastoma Progression 1.17
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 1.17
nELAVL HITS-CLIP in Alzheimer's Disease patients 1.16
Gene expression profiling of LNCaP cells following shRNA-mediated knockdown of TMEFF2 and growth in presence and absence of dihydrotestosterone 1.15
Molecular Pathology of adverse local tissue reaction caused by metal-on-metal implants 1.14
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma 1.13
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 1.13
Functional role of CPPED1 in trophoblasts. 1.12
Discovering human diabetes-risk gene function with genetics and physiological assays 1.12
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 1.12
Modeling Trilateral Retinoblastoma using Human Embryonic Stem Cells 1.12
FMR1 reactivating treatments in Fragile X iPSC-derived neural progenitors in-vitro and in-vivo 1.11
Role of FGFR1 in neuronal devlopment 1.11
Analysis of MGE Transcriptomes with or without Ctnnb1 knockout in human through RNA Sequencing 1.11
Inhibition of Enhancer of Zeste Homologue 2 attenuates TGF-β dependent hepatic stellate cell activation and liver fibrosis 1.1
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 1.09
Single-cell RNA-Seq Investigation of Foveal and Peripheral Expression in the Human Retina 1.09
Gene expression analysis upon mtDNA depletion 1.08
Gene expression analysis upon mtDNA depletion [RNA-seq] 1.08
Enhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest 1.07
Heterozygous and homozygous knock-in of PIK3CA-H1047R into human iPSCs 1.07
A next generation sequencing based approach to identify extracellular vesicle mediated mRNA transfers between cells 1.05
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 1.0
Mutations in EBF3 disturb transcriptional profiles and cause intellectual disability, ataxia and facial dysmorphism 0.99
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq] 0.99
Alteration of the microRNA network during the progression of Alzheimer’s disease 0.99
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 0.98
Disease modelling of core pre-mRNA splicing factor haploinsufficiency 0.97
Studying iPSCs from a hibernating mammal reveals molecular mechanisms of cold resistance in neural tissues 0.97
X-Ray induced DNA-Hydroxymethylation changes 0.95
Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation 0.95
mitoCPR - a surveillance pathway that protects mitochondria in response to mitochondrial import stress 0.94
mitoCPR - a surveillance pathway that protects mitochondria in response to mitochondrial import stress [human] 0.94
Histone deacetylase inhibition enhances antimicrobial peptide but not inflammatory cytokine expression upon bacterial challenge 0.94
Global reduction in H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas 0.93
High-depth RNA sequencing of isogenic wild-type, PIK3CA-WT/H1047R and PIK3CA-H1047R/H1047R human iPSCs 0.93
The MEF2B Regulatory Network - RNA-seq data 0.93
The MEF2B Regulatory Network 0.93
In vivo genome editing restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers 0.91
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 0.89
Derivation and differentiation of haploid human embryonic stem cells [RNA-Seq 1] 0.89
Biomarkers of Cavernous Angioma with Symptomatic Hemorrhage (CASH) 0.89
Biomarkers of Cavernous Angioma with Symptomatic Hemorrhage (CASH) [RNA-seq] 0.89
yylncT acts as a gatekeeper of the mesodermal transcriptional program by local modulation of DNMT3B [human_2] 0.89
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 0.89
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 0.89
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 0.88
De novo reconstruction of human adipose reveals conserved lncRNAs as regulators of brown adipogenesis 0.88
Generation, transcriptome profiling, and functional validation of cone-enriched human retinal organoids 0.88
Gene expressions of H9s in different culture systems 0.87
Transposon-based construction of strand-specific RNA-seq libraries 0.86
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 0.85
Functional Haploid Human Oocytes Generated from Polar Body Genomes (RNA-Seq) 0.84
Functional Haploid Human Oocytes Generated from Polar Body Genomes 0.84
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 0.84
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 0.84
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 0.84
Transcriptomics profiling of Alzheimer’s disease reveal novel molecular targets 0.84
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 0.83
Transcriptomic analysis of human iPS cells derived from fragile X syndrome patients during neural differentiation 0.83
Concomitant BCORL1 and BRAF mutations in vemurafenib-resistant melanoma cells 0.81
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 0.81
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 0.81
FUS KO mRNA sequencing and anti-FUS RNA immunoprecipitation sequencing 0.8
RNA-seq analysis of hPSC-derived brain pericyte-like cells, hPSC-derived neural crest stem cells, and primary human brain pericytes 0.8
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 0.8
A RUNX2-mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells 0.8
Expression profile of LNCaP/AR cells with or without HNF4G expression grown for long term in charcoal stripped-serum (CSS) media 0.79
Transcriptome profiling of de-differentiated chondrocytes over-expressing miR-138 or miR-181ab1 during osteogenic induction 0.79
Gene expression changes in HSV-1 infected HeLa cells with knockdown of B2M 0.78
Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic β-cell death 0.78
The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression 0.77
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 0.77
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 0.74
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 0.74
The cohesin release factor WAPL restricts chromatin loop extension. [RNA-Seq] 0.74
The cohesin release factor WAPL restricts chromatin loop extension. 0.74
A transcriptome dataset revealing the molecular features of breast cancer stem cells 0.73
FOXA1 Chromatin Binding is Regulated by LSD1-Mediated Demethylation 0.71
RNA-Seq with DHT induction and/or GSK treatment at 24, 48 hrs and 2 weeks 0.71
Deep sequencing of transcript levels of human embryonic stem cell derived mesothelium (epithelial and mesenchymal forms) and mesothelium from neonatal mouse E15.5 of the heart, lung, liver and gut and ChIP-seq data of the mesenchymal form of mesothelium 0.7
Microsatellite expansion RNA visualization, elimination, and reversal of molecular pathology by RNA-targeting Cas9 0.69
ARID1A and ARID1B loss in HCT116 cells 0.69
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 0.68
FUS mutant human motoneurons transcriptome analysis reveals altered pathways and impairment of microRNA function 0.68
Single-Cell Transcriptome Analysis of Lineage Diversity and Microenvironment in High-Grade Glioma 0.68
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis 0.66
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 0.65
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 0.65
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 0.64
Modulation of nonsense-mediated decay by rapamycin 0.64
Epithelial-mesenchymal transition markers screenedina cell-based model and validated in lung adenocarcinoma 0.63
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 0.62
The age and genomic integrity of neurons after cortical stroke in humans 0.6
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 0.58
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 0.57
Cooperative and Antagonistic Transcriptional Regulation by BRG/BRM [RNA-seq] 0.56
Co-regulation of transcription by BRG1 and Brm, two mutually exclusive SWI/SNF ATPase subunits 0.56
Hyper-activation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2 0.56
A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [RNA-seq] 0.56
0.55
An integrative analysis of non-coding regulatory DNA variations associated with autism 0.55
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 0.54
The DPYSL2 gene connects mTOR and schizophrenia 0.54
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 0.54
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 0.54
Integrated Multi-omic Analysis of Esthesioneuroblastomas Identifies Two Subgroups Linked to Cell Ontogeny 0.53
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 0.52
CD133hi, Notchhi, DP (double positive) and DN (double negative) in GBML8 and GBML20, both patient-derived glioblastoma tumorsphere cultures 0.52
Identification of Tissue-Specific Protein-Coding and Noncoding Transcripts across 14 Human Tissues Using RNA-seq 0.51
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 0.49
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 0.49
Canonical and non-canonical regulatory roles of androgen receptor variant 7 in prostate cancer 0.48
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells 0.48
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells (RNA-seq) 0.48
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function 0.47
The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma [RNA-Seq Tumor] 0.46
Dissecting neural differentiation regulatory networks through epigenetic footprinting 0.45
RNAseq of Extracellular vesicle RNAs and cellular RNAs from HPASMCs with or without TGF-b1 or BMP4 treatment 0.45
Preliminary Report of Transplantation of Human Fetal Retinal Pigment Epithelial Cells on Age-related Macular Degeneration Patients 0.43
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 0.4
Derivation and differentiation of haploid human embryonic stem cells 0.4
CHCHD2 gene KO effect in iPSC drived motor neurons 0.39
Epigenomic conservation of transposable element silencing 0.38
Epigenomic conservation of transposable element silencing [RNA-seq] 0.38
UBE3A-mediated regulation of imprinted genes and epigenome-wide marks in human neurons 0.37
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 0.33
Single cell transcriptomics analysis of induced pluripotent stem cell-derived cortical neurons reveals frequent dual layer identity 0.33
Activin/Smad2-induced H3K27me3 reduction is crucial to initiate mesendoderm differentiation of ES Cells 0.32
TGFβ1-mediated functional inhibition of mesenchymal stromal cells in MDS and AML 0.32
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.32
Next Generation Sequencing Study of Circadian Changes in Transcriptome of Human Pineal Gland 0.32
A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors 0.31
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 0.26
Small-molecule targeting of brachyury transcription factor addiction in chordoma 0.26
Pseudotime Ordering of Single Human Beta-Cells Reveals States of Insulin Production and Unfolded Protein Response 0.25
Comparative analysis of WT and ZEB1 KO cells in different stages during differentiation 0.25
RNA-Seq in PWS iPSC-derived neurons 0.24
RNA-Seq Analysis in purified iPS cell-derived neuronal samples 0.24
SF3B1 Degron knockdown RNA-seq 0.22
Rapid neurogenesis through transcriptional activation in human stem cell (RNA-Seq) 0.21
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 0.21
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 0.19
Transcriptome analysis of diverse cell types infected with human cytomegalovirus 0.19
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 0.18
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 0.18
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 0.18
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 0.17
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 0.17
Identifying markers predicting successful graft outcome for clinical translation of hESC-based cell therapy for Parkinson’s disease 0.16
a-synuclein accumulation in an iPSC derived model of early onset sporadic Parkinson’s Disease reveals novel drug targets 0.16
RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells II 0.16
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq 2] 0.15
Gene expression in mature and immature human ES-derived beta cells, and sorted beta-cells from adult islets 0.15
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 0.13
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 0.13
The global transcriptome analysis in the time course of hESC-derived cardiac differentiation 0.12
Low H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas 0.12
Transcriptomic Analysis of Endothelial Cells from Fibrovascular Membranes in Proliferative Diabetic Retinopathy 0.12
CHD1 regulates cell fate determination by activation of differentiation-induced genes 0.11
Altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency 0.11
Characterization and transplantation of enteric neural crest cells from human induced pluripotent stem cells 0.11
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.1
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 0.08
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 0.08
Human pluripotent stem cell-derived brain tumor model uncovered embryonic stem cell signature as a key driver in atypical teratoid/rhabdoid tumor (RNA-Seq) 0.08
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 0.06
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 0.06
RNA Expression Profile of Calcified Bicuspid, Tricuspid and Normal Human Aortic Valves by RNA Sequencing [BAV] 0.04
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.03
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 0.03
Reversing Abnormal Neural Development by Inhibiting OLIG2 in Down Syndrome Human iPSC Brain Organoids and Neuronal Mouse Chimeras 0.03
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 0.01


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