Gene Query: TOLLIP

Dataset Description Geneva Score
Effects of Cardiac Glycosides on RNA Expression in Prostate Cancer LNCaP-abl Cells 80.66
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 64.56
Targeting JNK Pathway Expands Human Hematopoietic Stem Cells 27.14
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile 23.09
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile [mRNA-Seq] 23.09
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 21.71
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 20.89
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth 20.26
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia 18.74
ENPP1 Mutation Causes Recessive Cole Disease by Altering Melanogenesis 18.02
Dynamic epigenetic remodeling underlies microRNA-mediated transdifferentiation of human adult fibroblasts into neuronal subtypes 17.25
Investigation into human Tra2 protein-dependent splicing in MDA-MB-231 cells using iCLIP and RNA-seq 16.56
TCF7L1 knockdown in pancreatic cancer 16.37
ZNF804A transcriptome networks in differentiating human neurons derived from induced pluripotent stem cells 16.2
circRNA-sequencing 15.17
Gene expression profile of HGC27 and LMSU gastric cancer cell p53 KO and KD 14.03
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways 13.6
Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes 13.15
A pooled single-cell genetic screen identifies regulatory barriers in the continuum of the epithelial-to-mesenchymal transition 13.14
ETV7 and interferon response 13.0
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 13.0
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing 12.46
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells [RNA-seq] 12.33
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells 12.33
RNA-Seq analysis and comparison of corneal epithelium in keratoconus and myopia patients 12.2
Dual modulation of neuron specific microRNAs and the REST complex promotes functional maturation of induced human adult neurons 12.13
Peroxisome Proliferator-activated Receptor gamma- Deficiency in Endothelial Cells Impairs Angiogenic Capacity by Loss-of E2F1 Mediated Wnt Effector Genes 12.13
Comprehensive evaluation of differential gene expression analysis methods for RNA-seq data 12.03
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (22RV1 RNA-seq) 11.94
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability 11.94
Cleavage Factor Im as a key regulator of 3’ UTR length 11.84
Gene expression profile using RNA-seq in WC00060 or SR-0788 cells transfected with siRNA for KPC1 or control 11.27
Pitfalls in Single Clone CRISPR-Cas9 Mutagenesis to Fine-map Regulatory Intervals 11.06
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 10.98
Convergent exaptation of Alu and B/ID SINEs for Staufen-mediated mRNA decay 10.87
STVI-120 Induction of differentiation in human epidermal stem cells followed by differential splicing analysis 10.81
Understanding the reproducibility and robustness of the kidney organoid differentiation protocol using RNA-seq 10.63
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 10.62
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 10.17
Pharmacologic inhibition of STAT5 in AML 10.14
Global Bidirectional Transcription of the Epstein-Barr Virus Genome During Reactivation 9.67
Transcriptional profile of CAOV2 ovarian cancer cells with TAZ silencing 9.43
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 [HET] 9.4
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer [RNA-seq] 9.24
Clinical and genomic crosstalk between glucocorticoid receptor and estrogen receptor α in endometrial cancer 9.24
RNA-Seq of over-expression and knockdown of the lncRNA SLNCR1 in melanoma cells 9.23
UBC9 knockdown in bladder cancer T24 cell lines 9.02
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 8.97
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 8.97
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 8.97
RNA-Seq analysis of primary human keratinocytes exposed to Cannabidiol 8.96
RNAseq analysis of the human neutrophil transcriptome, with and without in vitro cytokine stimulation 8.87
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) [RNA-seq] 8.8
Co-expression of CD163 and CD141 Identifies Human Circulating IL-10-Producing Dendritic Cells (DC-10) 8.8
Expansion, in vivo-ex vivo cycling and genetic manipulation of primary human hepatocytes 8.69
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 8.59
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 8.52
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 8.5
DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation 8.48
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 8.48
Gastrointestinal Stromal Tumor Enhancers Support a Transcription Factor Network Predictive of Clinical Outcome 8.48
NAPRT activation of macrophages 8.41
Selective modulation of inflammatory Natural Killer (NK) cell phenotypes following histone H3K27 demethylase inhibition 8.4
Selective modulation of inflammatory Natural Killer (NK) cell phenotypes following histone H3K27 demethylase inhibition [RNA-Seq] 8.4
Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer 8.39
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 8.35
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells 8.24
Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells [RNA-seq] 8.24
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 8.23
Next generation sequencing of human hepatic stellate cell line, LX-2 treated with recombinant human TGF-β1, with DMSO or ML290 (5 µM) for 72h. 8.2
Genome wide mapping of polyadenylation sites in proliferating and contact-inhibited cells and cells with knockdown of cleavage and polyadenylation factors 8.09
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance 8.07
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 8.06
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 8.06
PTP4A1 phosphatase is overexpressed in systemic sclerosis fibroblasts and promotes TGFb signaling 8.04
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 8.03
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 8.03
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation (Ribo-seq, RNA-seq) 8.0
Gene expression changes in human melanoma cell lines compared to primary melanocytes 7.91
Human induced pluripotent stem cell-derived vocal fold mucosa mimics development and responses to smoke exposure 7.89
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia 7.77
A TFIID-SAGA perturbation that targets MYB and suppresses acute myeloid leukemia (RNA-seq) 7.77
Time-dependent regulation of cellular programming of monocytes by NCOR2 [RNASeq_KD] 7.72
TGF-β regulation of miRNA expression in pancreatic cancer 7.71
RNA-sequencing WT vs SOCS3 knockout Glioblastoma stem-cells 7.67
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 7.66
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells 7.66
Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells [RNA-seq] 7.66
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 7.59
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 7.57
Profiling of gene expression using RNA-Seq in fibroblasts, iPSCs, iPSC-derived neurons and cells overexpressing Onecut transcription factors 7.52
Changes in chromatin accessibility and gene expression induced by overexpression of ONECUT transcription factors 7.52
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_RNA-seq] 7.5
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 7.39
Development of an In Vitro Human Liver System for Interrogating Non-Alcoholic Steatohepatitis 7.37
Effect of CTCF and Rad21 knockdown on SLK cells and KSHV gene expression 7.29
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 7.2
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression 7.19
Transcriptome profiling in primary human skeletal myotubes with MondoA knockdown 7.16
MondoA Links Muscle Lipid Accumulation and Insulin Resistance Driven by Nutrient Overload 7.16
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 7.14
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 7.12
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 7.12
Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells. 7.06
Novel Targeting of Transcription and Metabolism in Glioblastoma 7.05
Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth 7.02
A genome-wide long noncoding RNA CRISPRi screen identifies PRANCR as a novel regulator of epidermal homeostasis 7.0
Transcriptomics of human macrophages upon infection with Legionella pneumophila and two isogenic mutants, LamA and AnkH using RNA-seq 7.0
Transcriptomes analysis for the regulation of Z36 induced autophagy in HeLa cell death 6.97
Expression analysis of primary human monocytes stimulated with an anti-TLR10 mAb (5C2C5) 6.91
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 6.83
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 6.82
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 6.78
Flura-seq identifies organ-specific adaptations in metastasis-initiating cells 6.76
SUV420H2 knockdown in PANC-1 6.74
Transcriptome profiling of microRNA-mediated neuronal reprogramming with REST repression at day 7 6.66
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 6.65
LncRNA-GAS5 negative regulation of YAP-target genes expression 6.63
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 6.61
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 6.59
MLL-AF4 binds directly to a BCL-2 specific enhancer and impacts H3K27 acetylation 6.46
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 6.45
TOP2B disturbed the quality of human oocytes with advanced maternal age 6.39
CSL 6.39
CSL RNA-Seq on HKC and SCC cell lines 6.39
Profiling of circular RNAs in gastric cancer tissues and adjacent normal tissues 6.39
RNA sequencing (RNA-SEQ) of EPAS1 knockdown by siRNA in endothelial cells 6.39
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 6.34
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 6.34
Gene expression profiles of BxPC-3, MiaPaCa-2 and PANC-1 cell lines treated with DMSO and THZ1 respectively 6.29
LNCaP treated with iBET 6.28
RNAseq of HEK293 cells after Chtop knockdown 6.23
Co-transcriptional loading of RNA export factors shapes the human transcriptome 6.23
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 6.23
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 6.21
IGF2BP3 controls cancer cell invasiveness by modulation RISC function 6.16
Hypoxic regulation of transcription in HUVEC is mediated by EPAS1 6.12
Silencing p300 in MCF7 cells to study expression and alternative splicing 6.12
MUC1-C Drives Lineage Plasticity in Progression to Neuroendocrine Prostate Cancer 6.09
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 6.04
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 6.04
Epigenomic profiling reveals the key function of histone H3K9 methylation during tumor transformation process 6.02
Expression analysis of THP1 cells following shRNA knock-down of RUVBL2 6.0
Impeding transcription of expanded microsatellite repeats by deactivated Cas9 5.98
Next Generation Sequencing Facilitates Quantitative Analysis of human patient derived primary Glioblastoma (GBM) cancer cell Transcriptomes 5.95
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 5.93
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 5.93
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 5.93
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 5.85
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells 5.83
Cell responses to dysregulated VZV-induced cell-cell fusion 5.81
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 5.8
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 5.76
Dermal fibroblasts play a central role in skin model protection against C. albicans invasion 5.76
Indoxyl sulfate stimulates angiogenesis by regulating reactive oxygen species production via CYP1B1 5.75
Gene expression in PANC1 cells treated with Rakicidin 5.74
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy 5.74
Hyper-excitability of Neurons generated from Patients with Bipolar Disorder 5.69
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 5.69
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 5.69
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines [RNA-Seq] 5.64
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines 5.64
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 5.63
A novel CRISPR-engineered prostate cancer cell line defines the AR-V transcriptome and identifies PARP inhibitor sensitivities. 5.61
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 5.6
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 5.59
Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic Cells 5.58
Reprogramming by de-bookmarking somatic transcriptional program via targeting the BET bromodomains 5.54
G-quadruplex structures mark human regulatory chromatin 5.52
SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 5.52
Molecular pathogenesis of human prostate basal cell hyperplasia reveals a keratinocyte metaplasia 5.52
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 5.52
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 5.52
miR941 overexpression experiment 5.51
Lipid degradation promotes prostate cancer cell survival 5.5
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 5.47
An integrative network biology analysis identifies miR-508-3p as the determinant and a prognosis biomarker of the mesenchymal subtype ovarian cancer 5.47
RNAseq analysis of ESRP regulated splicing events in prostate cancer 5.44
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 5.42
Decrease in EZH2 histone methyltransferase mediates the effects of fluid shear stress (FSS) in endothelial cells 5.42
Reprogramming postnatal human epidermal keratinocytes toward functional neural crest fates 5.41
Crizotinib v. DMSO in SW480 cells 5.38
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq] 5.36
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine 5.36
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 5.34
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 5.34
Genome-wide transcriptome profiling of NEDD9-regulated genes using RNA-seq 5.33
Impact of dieldrin on transcription in Jurkat T cells 5.32
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 5.27
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 5.25
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 5.24
RNA-sequencing time course of Human Intestinal Epithelial Cells (HIECs) following knockdown of miR-30bcd using complementary locked nucleic acids 5.24
RNA-seq analyses of human prostate cancer cells 5.19
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 5.18
Next-generation sequencing of human dermal fibroblasts transdifferentiated towards the otic lineage 5.16
RNAseq of IL-36 stimulated primary human keratinocytes 5.15
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 5.15
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation 5.15
A zebrafish melanoma model reveals emergence of neural crest identity during melanoma initiation [human cell line RNA-seq] 5.15
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines 5.14
Next Generation Sequencing of Transcriptomes of Cutaneous Melanocytes and Metastatic Melanoma Cell Lines (mRNA-Seq) 5.14
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1 and H1 after SNAI1 deletion at Day2 after human early hematopoietic differentiation . 5.14
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 5.12
Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate 5.12
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 5.08
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 5.08
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 5.07
Massive parallel sequencing uncovers actionable FGFR2-PPHLN1 fusion and ARAF mutations in intrahepatic cholangiocarcinoma 5.05
Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells 5.04
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 5.04
Transcriptomic profiling of cleavage-resistant RIPK1 induced autoinflammation syndrome patients 4.99
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 4.99
Discovery of a Drug Candidate for GLIS3-Associated Diabetes 4.99
Episomal HBV persistence within transcribed host nuclear chromatin compartments involves HBx 4.99
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 4.98
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 4.96
Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 4.95
Human CD11b+ macrophages - Aging of hematopoietic stem cells is driven by regional specialization of marrow macrophages 4.95
Transcriptome analysis of BAP1 knockout and restoration 4.94
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 4.94
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 4.93
Catalogue of differentially expressed long non-coding RNAs following activation of human and mouse innate immunity 4.87
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 4.87
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 4.77
Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance 4.77
Quantitative Analysis of negative control and overexpression-TRIB1 in PC3 and DU145 Transcriptomes 4.76
Identification of IL-27 as potent regulator of inflammatory osteolysis associated with vitamin E-blended ultra-high molecular weight polyethylene debris of orthopedic implants 4.76
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch3] 4.73
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 4.72
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 4.7
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 4.65
Mechanosensitive ion channel regulates tissue stiffening to promote glioma aggression 4.65
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  4.64
Global gene expression profile of human peripheral blood-derived endothelial colony-forming cells is similar to coronary artery and umbilical vein endothelial cells 4.61
A map of gene expression in neutrophil-like cell lines 4.6
Evaluating pre-clinical models for studying NASH driven HCC. 4.53
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq] 4.53
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 4.53
ZFR coordinates crosstalk between RNA decay and transcription in innate immunity 4.48
Epigenetic Inactivation of Cysteine Dioxygenase Type 1 Contributes to ROS-dependent Progression of Colorectal Cancer 4.46
RNASEQ Analysis of sh-TRC and sh-MIR100HG in the triplex negative breast cancer 4.44
RNA sequencing of CACO-2 cells incubated with bifidobacteria grown on human milk oligosaccharides. 4.4
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells 4.33
Bioinformatics analysis of transcriptome related to blood stasis syndrome in diabetes mellitus patients 4.28
Genome-wide identification of cancer-specific alternative splicing in circRNA 4.28
Highly-motile versus unsorted MDA-MB-231 breast cancer cells 4.26
RNAseq to determine whether bidirectional transcription occurs over transposable elements following depletion of SETDB1 in THP-1 AML Cells 4.22
The Glioma-Infiltrating T Cell Receptor Repertoire 4.21
R430: A potent inbibitor of DNA and RNA viruses 4.2
Integrative analysis of mRNA and lncRNA profiles identified pathogenetic lncRNAs in esophageal squamous cell carcinoma 4.18
Identification of atheroprone shear stress responsive regulatory elements in endothelial cells 4.17
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 4.15
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition 4.15
Enhancement of direct reprogramming from fibroblasts to epithelial lineages by OVOL2-induced mesenchymal-to-epithelial transition [CAGE] 4.15
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 4.09
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas [Human RNA-Seq] 4.08
H3.3K27M cooperates with p53 loss and Pdgfra gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas 4.08
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 4.08
The dynamics of cellular response to therapeutic perturbation using multiplexed quantification of the proteome and transcriptome at single-cell resolution 4.07
nELAVL HITS-CLIP in Alzheimer's Disease patients 4.07
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 4.04
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L 4.01
Hepatitis C virus functionally sequesters miR-122 4.0
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 4.0
The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis 3.99
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens [RNA-Seq] 3.97
Inhibitors of the histone methyltransferases EZH2/1 induce a potent antiviral state and suppress infection by diverse viral pathogens 3.97
Identification of monocyte-like precursors of granulocytes as a mechanism for accumulation of PMN-MDSC in cancer 3.95
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 3.91
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 3.9
Identification of the networks that regulate human monocytic myeloid-derived suppressor cell differentiation into inflammatory macrophages 3.88
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 3.83
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 3.83
Single Cell Sequencing Reveals Gene Expression Signatures Associated with Bone Marrow Stromal Cell Subpopulations and Time in Culture [NGS_bulk cell RNA-seq] 3.82
Effect of PDZ domain binding Kinase inhibition using TOPK-32 (called PBKi) on C4-2 cell transcriptome 3.78
Long non-coding RNA TYKRIL controls pericyte function and survival in the cardiovascular and central nervous system through regulation of p53 activity and PDGFRß expression 3.77
Gene expression profiles of PD1-high, PD1-intermediate, and PD1-negative tumor-infiltrating CD8 T cells in hepatocellular carcinoma 3.72
Modeling and characterization of the dynamic gene regulatory networks underlying cancer drug resistance based on time-course RNA-seq data 3.7
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 3.69
MDM2 and MDM4 are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors 3.63
Transcriptomic analysis of senescent cells upon PTBP1 knockdown. 3.6
Differential expression of pancreatic cancer PANC1 cells treated with pilocarpine 3.58
RNA editing in nascent RNA affects pre-mRNA splicing 3.58
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 3.56
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability [RNA-Seq] 3.53
Neuronal brain region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability 3.53
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 3.52
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 3.52
Transcriptome analysis of VCaP xenografts resistant to dual therapy with abiraterone and enzalutamide 3.52
Immunological Imbalance in Fibrodysplasia Ossificans Progressiva Revealed by PBMC Transcriptome Analysis 3.51
Transciptomic profiling of human fetal lung samples 3.44
Transcriptome of diurnal human blood neutrophils 3.44
Transcriptome changes due to nuclear penetration of cancer extracellular vesicles 3.42
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (scRNA-Seq) 3.41
Robust generation of honemogeneous midbrain organoids with in vivo–like cellular composition facilitates neurotoxin-based Parkinson’s disease modeling 3.41
ERK signaling regulates opposing functions of JUN family transcription factors in prostate cancer cell migration 3.39
Metastasis in triple negative breast cancer is dependent on ΔNp63/CXCL2/CCL22-mediated recruitment of myeloid-derived suppressor cells 3.36
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 3.33
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain 3.32
Deciphering H3K4me3 Broad Domains Associated With Gene Regulatory Networks and Conserved Epigenomic Landscapes in the Human Brain [RNA-Seq] 3.32
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 3.32
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 3.3
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 3.3
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer 3.29
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer (RNA-seq) 3.29
Neutrophils in systemic onset Juvenile Idiopathic Arthritis display sepsis-like features which can be reverted by IL-1 blockade 3.27
Paxillin regulates genomic networks in prostate cancer [C4-2] 3.24
GIST cell cycle dysregulation is required for progression to high-risk disease but not for resistance to kinase inhibitors 3.22
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 3.22
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 3.22
Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cell Lines 3.21
CENPA-Bound Genes and Transcriptional Profiling of CENPA-Depleted Prostate Cancer Cells 3.21
Genes regulated by soluble guanylyl cyclase in VCaP prostate cancer cells 3.2
Global gene expression analysis of human monocyte-derived dendritic cells (DCs) treated with HMGN1 (N1) and R848 alone or in combination. 3.13
Effect of PBK knockdown on C4-2 cell transcriptome 3.11
The MEF2B Regulatory Network 3.1
The MEF2B Regulatory Network - RNA-seq data 3.1
KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors 3.09
Molecular characterization of BRSK2 and BRSK1 kinases as negative regulators of the NRF2 transcription factor 3.08
RNA-seq of shEZH2 cells 3.05
The flightless I protein is involved in the genome-wide mRNA post-transcriptional regulation in lung carcinoma cells 3.01
The phosphatidylinositol 3-kinase pathway as a potential therapeutic target in bladder cancer 3.01
Coordinated regulation of synthesis and stability of RNA during the acute TNF-induced proinflammatory response 3.0
SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF 2.97
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes (RNA-Seq) 2.9
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes 2.9
Multidimensional Assessment of the Host Response in Mechanically Ventilated Patients with Suspected Pneumonia 2.9
Small-molecule targeting of brachyury transcription factor addiction in chordoma 2.89
Hydroxychloroquine inhibits responses to group A streptococcus in peripheral blood mononuclear cells 2.89
Tracing transcriptome profiles of human oocyte cultured by growth hormone or not in vitro by single cell RNA-seq 2.87
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 2.87
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation (RNA-seq data) 2.86
Stochastic genome - nuclear lamina contacts are linked to histone H3K9 dimethylation 2.86
Endothelial-AGO1-knockout (EC-AGO1-KO) mice and wild-type (WT) littermates 2.84
RNA Seq of HMVEC under hypoxia 2.84
Gene expression profiles of 4-1BB+PD-1-high, 4-1BB-PD-1-high, and PD-1-int tumor-infiltrating CD8 T cells in hepatocellular carcinoma 2.83
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 2.83
A cell cycle-based functional screen to identify lncRNA-based cancer biomarkers 2.83
Gene expression analysis of human hepatocellular cancers 2.79
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 2.72
Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state. 2.72
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 2.69
Radiomic and gEnomic approaches for the enhanced DIagnosis of REnal Cancer (REDIRECt): A translational pilot study 2.66
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 2.61
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 2.59
Differential gene expression by suppression of either SOX2 or TP63 in KYSE70 human esophageal squamous carcinoma cell line. 2.52
Genome-wide RNA-sequencing of human islets 48 hour after transduction with adenoviruses expressing either GFP (control), or histone chaperone ASF1B. 2.48
Splicing and epigenetic factors jointly regulate epidermal differentiation 2.42
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 2.4
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 2.4
LKB1, Salt-Inducible Kinases, and MEF2C are linked dependencies in acute myeloid leukemia (RNA-Seq) 2.4
LKB1, Salt-Inducible Kinases, and MEF2C are linked dependencies in acute myeloid leukemia 2.4
Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α 2.39
TSLP acts on neutrophils to drive complement-mediated killing of methicillin-resistant Staphylococcus aureus 2.39
Molecular characterization of gene regulatory networks in primary human tracheal and bronchial epithelial cells. 2.38
X-Ray induced DNA-Hydroxymethylation changes 2.37
Total RNAseq of human putamen and caudate nucleus tissues in healthy control and Bipolar Disorder individuals 2.36
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer [RNA-seq] 2.32
FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer 2.32
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 2.32
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 2.24
Genome-wide expression profiling of an in vitro model for studying esophageal epithelial differentiation 2.24
Regulation of hypoxia-inducible factor activity by ZMYND8 2.22
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 2.2
Systems-level analyses reveal a convergent pathway for progression of diffuse astrocytoma and potential role for resveratrol in delaying high-grade transformation 2.2
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 2.18
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 2.15
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 2.08
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 2.08
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq] 2.03
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 1.97
RNAseq of Extracellular vesicle RNAs and cellular RNAs from HPASMCs with or without TGF-b1 or BMP4 treatment 1.93
Comparative transcriptome analysis reveals that ECM-Receptor Interaction contributes to the venous metastases of hepatocellular carcinoma 1.93
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription.[RNA-seq and ChIP-seq] 1.9
PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription 1.9
Integrating the Epigenome to Identify Novel Drivers of Hepatocellular Carcinoma 1.89
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 1.86
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 1.86
RNA-Seq with DHT induction and/or GSK treatment at 24, 48 hrs and 2 weeks 1.82
FOXA1 Chromatin Binding is Regulated by LSD1-Mediated Demethylation 1.82
RNA-seq in neutrophils from Juvenile Idiopathic Arthritis 1.79
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors 1.77
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 1.76
ChIP-seq and RNA-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells 1.74
RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits 1.74
Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk 1.73
Pancreatic Beta Cell Enhancers Regulate Rhythmic Transcription of Exocyst Triggering and Diabetes 1.73
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells (RNA-seq) 1.73
Role of NuRD subunits CHD3 and CHD4 in human melanoma cells 1.73
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 1.71
RNA-Seq gene profiling comparison from human cDC subsets and pre-cDC subsets 1.71
RNA-seq of human foreskin fibroblast cells lacking RB, p130, and p107 treated with doxorubicin. 1.65
Isolation and Functional Interrogation of Adult Human Prostate Epithelial Stem Cells at Single Cell Resolution 1.64
The transcription and translation landscapes during human cytomegalovirus infection reveal novel host-pathogen interactions 1.61
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 1.59
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 1.58
RNA Expression Profile of Calcified Bicuspid, Tricuspid and Normal Human Aortic Valves by RNA Sequencing [TAV] 1.58
Activity-dependent transcriptional changes in human neurons 1.58
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing 1.58
RNA sequencing of CACO-2 cells incubated with Bifidobacteria breve grown on human milk oligosaccharides. 1.57
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 1.53
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 1.53
CRISPR-Cas9 based screen for p53-bound enhancers that function in oncogene-induced senescence 1.51
Kidney compartment specific eQTL studies highlight causal genes and pathways for renal disease development 1.5
RNA-seq analysis in Cornea epithelial cells (CECs), skin epithelial cells (SECs), LSCs after knocking down PAX6 (3-D shPAX6 LSCs) and SESCs transduced with PAX6(3-D PAX6+ SESCs) upon 3-D differentiation 1.5
A single-cell transcriptome atlas of the human pancreas 1.47
eRNA: A graphic user interface-based tool for RNA sequencing data analysis 1.45
eRNA: A graphic user interface-based tool for RNA sequencing data analysis [mRNA-Seq] 1.45
Transcriptome of U251 cells overexpression complement component 7 1.41
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 1.4
RNA-Seq expression profiling of hepatocellular carcinoma and adjacent non-tumor liver tissues 1.37
Functional significance of the HIV-1 Tat signature amino acid residues 1.37
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 1.36
Gene expression profile in endometrial organoids cultured in normal follicular phase vs PCOS-like hormone profile 1.35
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 1.34
Gene expression profile of melanoma cell lines after overexpression or knockdown of KPC1 1.32
JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors 1.32
Expression charcaterization of an internal protocol developed to differentiate RPE cells 1.31
Heterogeneous maintenance of human tissue resident memory T cells based on efflux capacities 1.29
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 1.29
Neutrophils RNAseq from Generalised Pustular Psoriasis patients and healthy individuals 1.27
Paclitaxel plus Cirmtuzumab Achieves Greater Clearance of Patient-derived Xenografts By Targeting ROR1+ Breast Cancer Stem Cells 1.2
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 1.19
Inhibition of ERG Activity in Patient Derived Prostate Cancer Xenografts using the Small Molecule Inhibitor YK-4-279 1.13
PRRX2 and HEY2 double knock-down facilitates ASCL1-induced neuron conversion in human dermal fibroblasts. 1.12
Platelet Transcriptome Profiling in HIV and ABCC4 as a Biomarker of Platelet Activity 1.1
Identification of downstream genes regulated by YAP1 through knockdown and overexpression of YAP1 in U251 cell with a stably expression of mutant APP 1.1
Low carbohydrate diet study for non-alcoholic fatty liver disease patients 1.09
Identification of a LIF-responsive replication-competent human β cell 1.05
Expression levels of genes of NKG2C+ NK cells after in vitro treatment 1.01
Increased Neanderthal ancestry in genomic regions associated with lipid catabolism in contemporary Europeans 0.99
The circadian transcriptional landscape in primary human mammary epithelial cells 0.97
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 0.93
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 0.92
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 0.91
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 0.9
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 0.88
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.85
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.85
RNA-Sequencing of HUVEC treated with Tie2 activating antibody 0.84
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 0.81
Studying the selectivity of a targeted small molecule degrading a hypoxia-associated non-coding RNA 0.81
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 0.79
Identification of the RB loss-induced transcriptome in prostate cancer [RNA] 0.79
Identification of the RB loss-induced transcriptome and E2F1 cistrome in prostate cancer 0.79
Expression profiling of converted and control dermal BJ fibroblasts 0.78
p63 establishes epithelial enhancers de novo at critical craniofacial development genes 0.78
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 0.73
quanTIseq: quantifying immune contexture of human tumors 0.72
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 0.72
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes 0.71
RNA-sequencing of human vascular endothelial cells after si-RNA mediated gene silencing of interleukin-6 (IL6) 0.7
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived neurons 0.68
The age and genomic integrity of neurons after cortical stroke in humans 0.67
Finding missing proteins from epigenetically manipulated human cells 0.67
Impact of Escherichia coli K12 and O18 on human platelets: effects on platelet activation, spliced platelet RNAs and proteins 0.65
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing (Total RNA sequencing) 0.6
Loss of EGFR-DDEF1 signaling in metastatic and unresectable hepatoblastoma 0.58
Genome-wide expression analysis of human hTert immortalized fibroblasts after donwregulation of MCM7 0.55
Gene expression profiles of tumor-infiltrating CD8 T cells in hepatocellular carcinoma 0.52
Altered expression of signaling pathways regulating neuronal excitability in hippocampal tissue of temporal lobe epilepsy patients with low and high seizure frequency 0.52
Identification of global XBP1s target gene expression in human prostate cancer cells 0.51
miRNAs affected by antagomiR-17 treatment 0.49
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 0.48
MAIT cell RNA sequencing 0.48
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 0.42
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.42
Anti-inflammatory effect of indoleacrylic acid (IA) 0.41
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 0.4
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 0.4
Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer 0.38
Complement protein C1q modulates macrophage molecular signaling and inflammatory responses during ingestion of atherogenic lipoproteins 0.38
Methylation DNA mediated KLF4 binding activity in glioblastoma cells 0.36
Expansion of adult human pancreatic tissue yields organoids harbouring progenitor cells with endocrine differentiation potential 0.36
Modeling genome-wide transcriptional cis-regulation in n LNCaP-abl cell line after siRNA knock down of a series of gene factors [RNA-seq] 0.34
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 0.34
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 0.33
IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus 0.28
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 0.28
RNA sequencing and pathway analysis identify important pathways involved in hypertrichosis and intellectual disability in patients with Wiedemann-Steiner syndrome 0.27
Regulating Interleukin-2 activity with engineered receptor signaling clamps 0.27
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 0.26
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 0.26
SF3B1 Degron knockdown RNA-seq 0.25
RNA-seq characterization of downstream effects of upregulating SMN2 via down-regulating PRC2 or blocking the PRC2:SMN-AS1 interaction with a mixmer oligonucleotide 0.25
Gene expression profile of differentially recognized Mtb-epitopes as a function of disease history 0.23
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk 0.23
Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk [RNA-seq] 0.23
RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 0.22
RNA-seq and small RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 0.22
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 0.19
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 0.17
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells 0.15
CDK4/6 inhibitor resistance in prostate cancer 0.14
Transcriptome analysis of CD8+ T cells from healthy controls and patients wth CD46 deficiency 0.12
Analysis of transcriptomes of healthy donor and CD46 deficient CD8 T cells 0.12
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 0.11
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP [Ago2-miRNA-target mRNA complexes] 0.1
RNA-Seq data for five HER2 over-expressed samples with twelve green fluorescent protein control samples using human mammary epithelial cells 0.09
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.07


Contact Us

For scientific and technical queries contact Butte Lab @UCSF


Cite GENEVA Tool

Manuscript in Preparation