Gene Query: TP53BP1

Dataset Description Geneva Score
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 79.48
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 23.7
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 23.3
Stably-paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor Triptolide 22.69
Biological effect of chronic mistranslation in mammalian cells 22.63
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 21.89
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 21.57
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 20.11
Montelukast counteracts the influenza virus-induced block in unfolded protein stress response and reduces virus multiplication 18.31
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 17.96
Quantitative comparison between cellular mRNAs and exosomal mRNAs in human iPSC-derived motor neurons 16.58
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 16.31
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 15.79
BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors 15.78
Mechanistic Model-Guided Study of Embryonic Morphogenesis 15.44
Transcriptome data from human endocrine cells recovered from mouse grafts with pre-engraftment controls 15.2
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 15.01
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 14.61
Absence of NKG2D ligands defines human leukaemia stem cells and mediates their immune evasion 14.31
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (RNA-seq dataset) 14.3
mRNA expression in human DAOY cells 14.25
Genome wide miR-191 target profile determined by RIP and gene expression profiling 14.12
miR-191 regulates human cell proliferation and directly targets multiple oncogenes [seq] 14.12
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 14.08
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 14.08
The stress granule transcriptome reveals principles of mRNA accumulation in stress granules. 13.96
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 13.79
CpG dinucleotides introduced into gag can inhibit HIV-1 gene expression by modulating pre-mRNA splicing 13.76
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 13.55
Wide-scale analysis of alternative polyadenylation (APA) associated with proliferation and transformation using 3'-Seq 13.53
A TGFbeta-PRMT5-MEP50 Axis Regulates Cancer Cell Invasion through Histone H3 and H4 Arginine Methylation Coupled Transcriptional Activation and Repression 13.5
The effect of spontaneous acquisition of an extra chromosome 7 for engineered del(7q) on induced pluripotent stem cells (iPSCs) derived from patients with Shwachman Diamond Syndrome (SDS). 13.48
MOF acetyl transferase regulates transcription and respiration in mitochondria 13.3
The regulation of ferroptosis by TAZ in epithelial ovarian cancer 13.27
Differentiation enhances Zika virus infection in neuronal brain cells 13.26
IGF2BP3 controls cancer cell invasiveness by modulation RISC function 13.2
Characterization of parental and rociletinib-resistant derived H1975 cell lines 13.18
Knockdown of FOXP1 promotes the development of lung adenocarcinoma 13.15
RNA-seq of tumor cells following angiopellosis extravasation 13.04
Human Adipocytes Regulate Gene Expression in Triple-negative Breast Cancer Assessed by NGS Sequencing 12.95
Major roles of cyclobutane pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation 12.93
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 12.79
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 12.79
LNCaP treated with iBET 12.43
An in vitro human liver model by iPSC-derived parenchymal and non-parenchymal cells 12.43
Estrogen receptor and mTOR signaling rewires cancer metabolism in obesity-associated breast cancer 12.43
Transcriptomic characterization of a human in vitro model of arrhythmogenic cardiomyopathy under topological and mechanical stimuli 12.29
Genes significantly down or Up-regulated upon RNF219 knockdown 12.19
Exogenous pyruvate represses histone gene expression to inhibit cancer cell proliferation via the NAMPT-NAD + -SIRT1 pathway 12.08
Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells 11.82
circRNA-sequencing 11.8
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 11.71
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 11.71
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 11.6
Total RNA-seq in ALL-SIL upon JQ1 inhibition 11.55
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer [RNA-seq] 11.33
A Novel PI3K Regulator, ARID4B, Presents Synthetic Essentiality in PTEN-deficient Prostate Cancer 11.33
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 11.31
A novel P300 inhibitor reverses DUX4-mediated global histone H3 hyperacetylation, target gene expression and cell death 11.18
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 11.13
MLL-AF4 binds directly to a BCL-2 specific enhancer and impacts H3K27 acetylation 11.06
Gene expression profiling of leukemia cells following asparagine depletion 11.04
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 10.97
Transcriptome analysis of total RNA in human osteosarcoma cell line U2OS before and after inhibition of zinc finger protein ZNF768 10.95
Analysis of the Clustered Protocadherin (cPcdh) Locus in Human Pluripotent Stem and Derived Cells [RNA-seq II our of II] 10.85
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 10.65
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 10.63
Gene expression changes upon drug withdrawal (A375/451Lu cell lines) 10.59
WRN knockout effects upon gene expression in SW48 and OVK18 10.57
The effect of insulin on mRNA transcription of human pluripotent stem cells 10.44
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming 10.34
Bromodomain inhibition of the co-activators CBP/EP300 facilitates reprogramming (RNA-seq fibroblasts) 10.34
Transcriptomic Dynamics during Differentiation Process of Human Pluripotent Cells into Hepatocyte-like Cells 10.33
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 10.28
SETDB2 links E2A-PBX1 to cell cycle dysregulation in acute leukemia through CDKN2C repression [sequencing] 10.17
Impact of dieldrin on transcription in Jurkat T cells 10.16
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 10.13
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 10.13
RNA-sequencing of human peripheral blood mononuclear cells (PB MNCs) and induced neural progenitor cells derived from PB MNCs 9.96
Intron retention induced by microsatellite expansions as a disease biomarker. 9.94
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 9.92
Transcriptome profiling of influenza virus-infected human bronchial epithelial cells 9.9
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements 9.82
MenSCs inhibit HCC growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements [RNA-seq] 9.82
Single-cell Transcriptomic Atlas of the Human Retina Identifies Cell Types Associated with Age-Related Macular Degeneration 9.82
Searching for target genes of miR-508/509/506/514 in HCT116 cells 9.81
Next generation sequencing analysis of transcriptomes at different timepoints after chlorprothixene treatment in NB4 and Kasumi-1 cells 9.78
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 9.76
Transcriptome of TNF-a-treated and untreated HeLa cells before and after TFIIB knockdown 9.75
Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells 9.68
Function of HNRNPC in breast cancer cells by controlling the dsRNA-induced interferon response 9.66
Transcriptomic but not genomic variability confers phenotype of breast cancer stem cells 9.62
Characterization of Type I Interferon pathway during Hepatic Differentiation of Human Pluripotent Stem Cells and hepatitis C virus infection 9.52
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 9.5
Gene expressions of H9s in different culture systems 9.44
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 9.4
Epigenomic plasticity enables human pancreatic alpha to beta cell reprogramming 9.37
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 9.35
iRNA-seq: Computational method for genome wide assessment of acute transcriptional regulation from total RNA-seq data 9.32
Transcriptional Modulation of Human Endogenous Retroviruses in Primary CD4+ T Cells Following Vorinostat Treatment 9.24
Improved LCL to iPSC reprogramming: RNA Analysis of LCLs, reprogrammed iPSCs, and differentiated NSCs reveal potential regulatory and functional processes involved in these cellular transitions. 9.18
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 9.16
RNA sequencing of lncRNAs knockdown in human pancreatic cancer cell lines 9.1
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 9.06
Global Mapping of Human RNA-RNA Interactions 9.04
AMPK signaling for naïve pluripotency [Hs] 9.03
AMPK signaling for naïve pluripotency 9.03
RNA-seq in HepG2 and IMR90 cells 8.96
Evolution of a transcriptional regulator from a transmembrane nucleoporin 8.96
Bladder-cancer-associated mutations in RXRA activate peroxisome proliferator-activated receptors to drive urothelial proliferation 8.96
Bladder cancer associated mutations in RXRA activate peroxisome proliferator-activated receptors 8.96
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 8.96
XPO1 inhibition antagonizes MCL via nuclear retention of IkB: Selinexor demonstrates antitumor activities in both ibr-sensitive and ibr-resistant tumor cells 8.95
Transcriptional profile of CAOV2 ovarian cancer cells with TAZ silencing 8.94
MDM2 and MDM4 are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors 8.88
EP400 is required for Max and MCPyV mediated gene activation 8.85
Gene expression profile in response to HIF-1α inhibition together with PPARα activation and the postnatal factors (T3, IGF-1 and dexamethasone) in hiPSC-CMs 8.82
Codon usage optimization in pluripotent embryonic stem cells [RNA-seq] 8.8
Examining serotonergic neuron differentiation from human iPSCs 8.77
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 8.64
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 8.63
Differential expression of human parthenogenic stem cells, neural stem cells and DA progenitors. 8.59
Peroxisome Proliferator-activated Receptor gamma- Deficiency in Endothelial Cells Impairs Angiogenic Capacity by Loss-of E2F1 Mediated Wnt Effector Genes 8.56
Functional Screening in Human Cardiac Organoids Reveals a Metabolic Mechanism for Cardiomyocyte Maturation 8.56
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress 8.54
Expression data from fresh human embryonic lung epithelial tip and stalk cells and cultured organoids derived from tip and stalk. 8.48
RNA-dependent RNA polymerase sequence specificities of capsnatching viruses are tailored to aid viral replication 8.46
Transcriptomic changes mediated by β-amyloid in human aortic endothelial cells (HAOEC) 8.46
Toxoplasma gondii infection of human retinal pigment epithelial cells 8.43
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells 8.37
Heterogeneous maintenance of human tissue resident memory T cells based on efflux capacities 8.36
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 8.26
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 8.12
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 8.09
Regulation of highly expressed hCINAP on translatome 8.03
H3K27Ac in MCF7 Y537S ER mutant cells and RNAseq with and without treatment with THZ1 8.02
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 8.0
Effect of CRISPR-Cas9 mediated knock-out of integrin alpha2 on the transcriptome of DU145 prostate cancer cell grown as a spheroid culture 7.97
Genes regulated by soluble guanylyl cyclase in VCaP prostate cancer cells 7.96
Global transcriptional analysis and genome-wide analysis of chromatin state in extended pluripotent stem cells, primed pluripotent stem cells, and naïve pluripotent stem cells 7.95
Global transcriptional analysis of human extended pluripotent stem cells, human primed pluripotent stem cells, mouse extended pluripotent stem cells, and mouse embryonic stem cells by RNA-seq 7.95
RNA-seq analysis of A2780 and OVCAR3 human ovarian cancer cell lines after overexpression of collagen type XI alpha 1 (COL11A1) 7.95
Exploring the gene expression profile upon FXR1 knockdown in H358 cells using RNA-seq 7.95
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq2] 7.93
Transcriptome Analysis of CircMRPS35 mediated mRNA expression profiles 7.92
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 7.9
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 7.9
Expression profile of LNCaP/AR cells with or without HNF4G expression grown for long term in charcoal stripped-serum (CSS) media 7.89
Treatment of SW480 colon cancer cell induced xenografts with AZD and DBZ 7.88
Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) of BJ cells treated with Nutlin-3a, an MDM2 inhibitor, which induces p53. 7.87
Hypoxic transcriptome of SQ20B human head and neck cancer cells 7.8
Targets of CDK12 on ZR-75-30 breast cancer cells (RNA-seq) 7.8
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 7.8
Effect in HCT116 cells of 3hr cortistatin A treatment on gene expression. 7.78
Mediator kinase inhibition further activates super-enhancer-associated genes in AML 7.78
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq 7.78
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq and microarray 7.78
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 7.77
Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D 7.76
PTHrP overexpression in MCF7 cells 7.75
Transcriptomic analyssis following EHMT1/2 inhibition 7.74
Stimulation of isolated plasmacytoid dendritic cells (pDCs) with TLR9 agonist CpG C (CpG) and TLR7 agonist imiquimod (IMQ) 7.71
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 7.7
Fibroblasts in cholesteatoma activate osteoclasts. 7.68
Molecular Mechanisms of Endothelial Hyperpermeability 7.65
Trans-chromosomal regulation by a novel lincRNA required for adipogenesis that escapes X-chromosome inactivation 7.64
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 7.58
Loss of CREBBP results in gene expression repression in lymphoma cells 7.58
Differential expression of pancreatic cancer PANC1 cells treated with pilocarpine 7.58
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 7.55
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff 7.53
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging 7.51
RNAseq to determine gene expression changes following depletion of SETDB1 in THP-1 AML Cells 7.49
Stage-specific regulation of the WNT/β-catenin pathway enhances differentiation of hESCs into hepatocytes 7.46
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 7.44
Silencing SPIB in attached and floating state of H1703 lung cancer cells 7.43
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 7.41
Transcriptome analysis of AGS cells infected with Helicobacter pylori P12 7.33
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 7.33
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 7.26
Pericyte-like cells generated from human pluripotent stem cells support hematopoietic stem and progenitors ex vivo 7.24
Bioinformatics analysis of transcriptome related to blood stasis syndrome in diabetes mellitus patients 7.23
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 7.22
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [Primary RNA-Seq] 7.18
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 7.17
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 7.16
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes (RNA-seq) 7.15
Genomic and proteomic resolution of heterochromatin and its restriction of alternate fate genes 7.15
Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases 7.14
Combined use of astragalus polysaccharide and berberine attenuates insulin resistance in IR-HepG2 cells via regulation of the gluconeogenesis signaling pathway 7.14
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration 7.13
Human Induced Pluripotent Stem Cells Recapitulate Breast Cancer Patients’ Predilection to Doxorubicin-Induced Cardiotoxicity 7.12
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 7.12
Co-transcriptional loading of RNA export factors shapes the human transcriptome 7.1
RNAseq of HEK293 cells after Chtop knockdown 7.1
Epigenetic reprogramming at estrogen-receptor binding sites alters the 3D chromatin landscape in endocrine resistant breast cancer [RNA-seq] 7.05
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine resistant breast cancer 7.05
Human gut derived-organoids as model to study gluten response and effects of microbiota bioproducts in celiac disease 7.05
Heterogeneous effects of massive hypoxia pathway activation in kidney cancer 7.03
miRNAs affected by antagomiR-17 treatment 7.03
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 7.02
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 7.02
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 7.01
Human colon organoids reveal distinct physiologic and oncogenic Wnt responses 6.98
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 6.96
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq] 6.96
RNA-seq of naive and primed ES cells 6.95
ARID1A and ARID1B loss in HCT116 cells 6.93
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 6.92
Next Generation Sequencing Facilitates Quantitative Analysis of mesoderm posterior bHLH transcription factor 1(MESP1)+ and MESP1- cells' Transcriptomes 6.88
Non-transmissible measles virus vector with segmented RNA genome establishes different types of iPSCs from hematopoietic cells 6.86
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer [RNA-Seq] 6.82
LSD1 mediates AKT activity in PIK3CA mutant colorectal cancer 6.82
Molecular Criteria for Defining the Naive Human Pluripotent State 6.81
Impact of DNA MMR activity on antiviral gene expression in H441 cells infected with influenza A virus 6.79
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 6.79
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 6.72
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 6.72
Ribosome profiling and RNA sequencing of MCF10A-ER-Src and fibroblast cell transformation 6.71
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq2] 6.71
Integrin signaling regulates YAP/TAZ to control skin homeostasis 6.7
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma 6.66
Enhancer Sequence Variants and Transcription Factor Deregulation Synergize to Construct Pathogenic Regulatory Circuits in B Cell Lymphoma (RNA-Seq) 6.66
Analysis of chromosomal aberrations and recombination by allelic bias in RNA-Seq 6.62
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay 6.58
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 6.57
Activation of Wnt/beta-catenin in Ewing sarcoma cells antagonizes EWS/ETS function and promotes phenotypic transition to more metastatic cell states 6.53
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 6.45
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 6.45
Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS 6.43
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 6.43
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 6.37
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 6.34
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation [RNA-seq] 6.34
Androgen receptor functions as transcriptional repressor of Cancer Associated Fibroblast (CAF) activation 6.34
RNA-sequencing with micro-dissected boundary organoid into anterior, posterior, and boundary regions 6.32
Transcriptional changes after overexpression of proliferation drivers in human mammary epithelial cells. 6.29
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors 6.23
Coding mutations and loss-of-imprinting in human pluripotent cells derived by nuclear transfer and defined factors [RNA-Seq] 6.23
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 6.22
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 6.13
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 6.11
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 6.11
RNA-seq of human foreskin fibroblast cells lacking RB and/or p130 after doxorubicin treatment 6.1
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers 6.05
Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor Alpha Bound Enhancers [RNA-Seq] 6.05
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 6.05
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes 6.03
Membrane Metallo-Endopeptidase (Neprilysin) Regulates Inflammatory Response and Insulin Signaling in White Preadipocytes (RNA-Seq) 6.03
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 6.03
RNA-sequencing in irradiated and normal A549 cells. 6.01
FGF2 induces migration of human bone marrow stromal cells by increasing core-fucosylations on N-glycans of integrins 6.01
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 5.92
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 5.92
Identification of PAX7-induced transcriptional changes and PAX7 genomic binding during skeletal myogenic differentiation of H9 embryonic stem cells 5.9
Identification of PRMT5-dependent genes in ESA+CD24lowCD44+ MCF7 cells 5.87
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 5.82
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 5.82
Human cells contain natural double-stranded RNAs with potential regulatory capacity 5.78
Transcriptional repression in hypoxia is mediated by the Sin3A histone deacetylase complex [RNA-seq] 5.77
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_sgrna] 5.75
Apolipoprotein E4 Expression Causes Gain of Toxic Function in Isogenic Human Induced Pluripotent Stem Cell-Derived Endothelial Cells 5.69
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 5.66
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 5.66
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction [III] 5.54
RNA-sequencing 5.53
A transcriptome dataset revealing the molecular features of breast cancer stem cells 5.51
Effects on gene expression of doxorubicin in human stem cells-derived cardiomyocytes 5.44
RNA-seq of cultured human kidney peritubular microvascular endothelial cells following exposure to cyclosporine A 5.43
Gene expression profile of melanoma cell lines after overexpression or knockdown of KPC1 5.39
Subcellular RNA fractions of HSV-1 infected primary human fibroblasts 5.36
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 5.34
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 5.3
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 5.3
RNA sequencing of mechanically strained NHEKs and control NHEKs 5.25
Characterisation of the EZH2 regulated transcriptome in de novo transformed cells (RNA-Seq) 5.21
C9/ALS Human Embryonic Stem Cells and C9/ALS Induced Pluripotent Stem Cells 5.14
RNA deep sequencing analysis of glioma stem cells(GSCs) and non-GSCs 5.11
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  5.1
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 5.1
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 5.06
Human embryonic stem cells in E8 and AKIT culture medium 5.06
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell 5.06
Identification of Atrial Fibrillation associated genes and functional non-coding variants 4.96
Gene Expression Analysis of HUVEC Seeded rBEL Contructs at Low and High Phases of Glucose Consumption 4.91
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 4.9
Oxaliplatin resistance is enhanced by saracatinib via upregulation of ABCG1 and Wnt/β-catenin signaling in hepatocellular carcinoma 4.89
Next Generation Sequencing Facilitates Quantitative Analysis of colorectal cancer cells transfected with NC siRNA or RPL9 siRNA 4.85
Identification of miR-100 and miR-125b targets by AGO2 RIP-seq and RNA-seq after ectopic expression of miR-100 or miR-125b and evaluation of the TGFb expression signature in PANC-1 cells by RNA-seq 4.8
RNA-sequencing of human mammary epithelial cells (HMLEs) engineered to express either ER or ER-SOX4 with and without 4-OHT to induce nuclear translocation 4.79
polyA RNA Sequencing Analysis of HTR-8/SVneo cells after lnc-SLC4A1-1 overexpression 4.78
BET bromodomain inhibition 4.76
Effect of BET bromodomain inhibition with JQ1 in stressed human derived iPS cardiomyocytes 4.76
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 4.7
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest 4.69
Transcription elongation regulates genome 3D structure 4.68
BET bromodomain inhibitor iBET151 impedes human ILC2 activation and prevents experimental allergic lung inflammation 4.65
RNA-SEQ assay for wild type and CRISPR induced endoglin knockout human pulmonary artery smooth muscle cells (PASMC) 4.63
Transcriptome-wide modulation of splicing by the exon junction complex 4.61
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation (RNA-Seq) 4.59
5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation 4.59
An alternative CTCF isoform antagonizes canonical CTCF occupancy and changes chromatin architecture to promote apoptosis 4.53
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with tcons_00001221 shRNA or control shRNA 4.52
TFPa/HADHA is required for fatty acid beta-oxidation and cardiolipin re-modeling in human cardiomyocytes 4.51
DAOY-Notch1/Notch2 knockout: transcriptome comparison 4.51
Small extracellular vesicles are key regulators of non-cell autonomous intercellular communication in senescence via the interferon protein, IFITM3 4.44
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 4.44
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates (part 4) 4.39
Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates 4.39
Epidermal growth factor activates β-catenin via integrin-linked kinase to control proliferation of mesenchymal stromal cells. 4.39
Genome Wide Chromatin Mapping of accessibility (ATAC-seq) and H3K27ac histone modifications in CD56bright and CD56dim natural killer cells 4.35
Real-time observation of light-controlled transcription in living cells 4.33
The age and genomic integrity of neurons after cortical stroke in humans 4.32
Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells 4.27
Expression profiling of ILC transitional populations and Aiolos accessability and H3K27ac histone modifications in transfected MNK3 cells 4.2
RNA-Seq from human ILC transitional populations 4.2
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 4.2
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 4.18
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 4.17
LSD1 pharmacological inhibition in SET-2 containing wild type and mutant LSD1 [RNA-Seq] 4.17
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 4.15
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 4.14
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer 4.13
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 4.08
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC [Total RNA-Seq] 4.07
Integrative analysis of microRNAs and mRNAs in liver tissue and exosomes from blood of hepatitis C virus (HCV) related hepatocellular carcinoma (HCC) patient to identify biomarker and regulators of HCC 4.07
Capturing the Interactome of Newly Transcribed RNA 4.05
Capturing the Interactome of Newly Transcribed RNA (RICK) 4.05
The transcriptome and chromatin accessbility landscape of mammalian germline 4.04
RNAseq of quiescent (Q) and stress induced premature senescent (SIPS) fibroblasts treated with plant extract (1201) from Solidago vigaurea subspecies alpestris 3.97
Spatially Constrained Tandem Bromodomain Inhibition Bolsters Sustained Repression of BRD4 Transcriptional Activity for TNBC Cell Growth 3.96
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples 3.93
Gene expression in skeletal muscle in older individuals subject to ten days of complete bed rest. 3.93
RNA-Seq Analysis in hES/ iPS cell-derived neuronal samples 3.9
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes 3.89
Epigenetic modulation of β-cells by interferon-α via PNPT11-miR-26a-TET2 triggers autoimmune diabetes [RNA-seq] 3.89
Integration of kinase and calcium signaling at the level of chromatin underlines inducible gene activation in T cells 3.82
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 3.81
CD73 knockdown effect in pancreatic cancer cell lines 3.76
Transcriptional profiling identifies differential expression of long non-coding RNAs in Jo-1 associated and inclusion body myositis 3.74
Time series total RNA sequencing of a differentiation of human embryonic stem cells towards trophoblast lineage 3.74
The cohesin release factor WAPL restricts chromatin loop extension. 3.7
The cohesin release factor WAPL restricts chromatin loop extension. [RNA-Seq] 3.7
Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation 3.68
Transcriptome-wide discovery of microRNA binding sites in human brain by Ago2 HITS-CLIP 3.64
CDK12 mediated transcriptional regulation in U2OS cells 3.63
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 3.54
Multi-omic measurements of heterogeneity in HeLa cells across laboratories 3.49
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 3.48
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 3.48
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 3.4
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 3.37
Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells (longRNA-seq) 3.35
Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells 3.35
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 3.35
RNA Sequencing of Human iPS derived Cardiomyocytes 3.34
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity 3.31
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation 3.3
naive T cell heterogeneity after neonatal thymectomy 3.19
RNA sequencing analysis of triple cytokine-captured human CD4 T cells 3.17
Human Airway Smooth Muscle Transcriptome Changes in Response to Asthma Medications 3.16
RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures 3.1
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 3.09
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 3.09
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 3.02
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 2.95
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 2.92
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 2.87
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 2.87
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 2.85
LHX9 rescues KRAS suppression through transcriptional regulation of YAP1 [RNA-Seq] 2.85
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 2.8
Aneuploidy-induced cellular stresses limit autophagic degradation. 2.76
Cell cycle dynamics of human pluripotent stem cells primed for differentiation 2.72
Pain-driven transcriptome changes in synovium of knee osteoarthritis patients 2.71
RB tumor suppressor promotes cancer immunity through downregulating PD-L1 expression 2.69
Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells 2.69
GATA3 enhances the neurogenic potential of primary human astrocytes after traumatic injury [exp2] 2.68
Targeting MTHFD2 in Acute Myeloid Leukemia 2.66
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 2.65
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 2.65
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 2.65
CNOT1 and Transcriptomic Landscape of a HeLa Cell Line 2.61
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 2.6
A Novel Population of Human Cardiac Resident Mesenchymal Stem Cells 2.59
Total RNA-seq in ALL-SIL upon TLX1 knockdown 2.57
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes 2.52
Comprehensive Epigenetic Landscape of Rheumatoid Arthritis Fibroblast-like Synoviocytes [RNA-seq] 2.52
Priming mobilization of hair follicle stem cells triggers permanent loss of regeneration after alkylating chemotherapy 2.44
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 2.4
Transcriptome profiling of Caki2 cells re-expressing Polybromo-1 (PBRM1) 2.35
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 2.13
Investigation about Monocytes in metastatic breast cancer patients under chemotherapy +/- Avastin 2.12
Transcriptome wide identification of retained introns upon depletion of the splicing factors SNW1 or PRPF8 1.97
RNA-Seq analysis of human neutrophils isolated by different protocols (Polymorphprep and negative selection) and incubated with and without in vitro cytokine stimulation 1.97
RNA-seq analysis identifies different transcriptomic types and developmental trajectories of primary melanomas 1.94
RNA expression profiles from HUVECs overexpressing adenovirally delivered HIF1a and HIF2a proteins 1.9
Transcriptome Profiling Reveals the key genes and pathways involved in polycystic ovary syndrome [RNA-seq] 1.77
Identification of epigenetic interactions between miRNA and DNA methylation associated with polycystic ovarian syndrome 1.77
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 1.72
Function and hormonal regulation of GATA3 in human first trimester placentation 1.72
RNA-seq analysis of primary patient samples to characterize the CNS leukemia 1.71
Transcriptome analysis of CNS leukemia 1.71
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 1.7
ADAR1-editing of cellular and measles virus-derived duplex RNA 1.66
ADAR1-editing in HeLa, p150-KO and ADAR1-KO transcriptomes 1.66
Subcellular pathways shared by afflicted patients and mutant mice identify a new drug treatment for aortic aneurysm in Marfan syndrome 1.66
Truncation of LOC100288798 (SLC38A4-AS) lncRNA in human haploid KBM7 cell line 1.65
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 1.65
CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Humans 1.64
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 1.63
Aortic Valve Tissue: Stenosis vs. Sclerosis 1.59
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 1.58
Class I histone deacetylases HDAC1, 2 and 3 are histone decrotonylases 1.57
RNA-sequencing of Wnt-dependent and Wnt-independent of Glioblastoma stem cell cultures 1.53
Effect of ILF3 depletion in HeLa cells on RNA steady state levels 1.49
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 1.47
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration [RNA-seq2] 1.47
Gene expression profiles of isogenic single-cell derived clones of BRAF-mutated SK-MEL-5 melanoma cell lines 1.44
WNT signaling memory is required for ACTIVIN to function as a morphogen 1.43
Transposon-based construction of strand-specific RNA-seq libraries 1.43
RNA-Seq of SLNCR1 over-expression in the melanoma cell line A375 1.42
TGF-b-activated LncRNA LINC00115 is a critical regulator for glioma stem-like cell tumorigenicity 1.38
Aneuploidy triggers an immune response 1.35
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 1.34
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 1.28
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 1.26
The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC derived cardiomyocytes. 1.26
H3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation 1.22
H3K36 mutations promote sarcomagenesis through genome-wide remodeling of H3K36 and H3K27 methylation [RNA_Chondroblastoma_H3K36M_H3WT] 1.22
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis 1.22
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [RNA-Seq_Hs] 1.22
Anti-Inflammatory Effects of Budesonide in Human Fetal Lung 1.2
RNA expression profiles comparing primary and omental ovarian carcinoma samples 1.18
Pro-angiogenic Ginsenoside F1 and Rh1 Inhibit Vascular Leakage by Modulating NR4A1 1.16
Compare of gene expression between p16INK4A positive and negative regions of colon cancer from five patients 1.16
Effects of transcription on genome - nuclear lamina interactions 1.13
Effects of transcription on genome - nuclear lamina interactions: RNA-seq data 1.13
Proteomics identifies a marker signature of MAPKi resistance in melanoma 1.11
UMI-count modeling and differential expression analysis for single-cell RNA sequencing 1.05
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis [Quant-Seq] 1.04
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis 1.04
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia 1.02
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 1.02
Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains 0.98
Dual RNA-seq – High-resolution comparative Dual RNA-seq time-course 0.98
Specific labeling of stem cell activity in human colorectal organoids using an ASCL2-responsive minigene 0.97
Modeling Human Cancer-induced Cachexia (Human) 0.93
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 0.9
Transcriptome data of temporal and cingulate cortex in the Rett syndrome brain 0.89
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.89
RNA-seq of primary patient AML samples 0.83
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 0.79
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 0.79
UV_24h_GRO-Seq 0.74
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 0.73
Transcriptome analysis of human embryonic stem cells (hESCs) upon siRNA-mediated knockdown of hESC-essential genes 0.68
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 0.64
Induction of Cardiomyocyte Proliferation [pz-822_human] 0.64
Transcriptomic insights into human decidual and peripheral blood CD4 T cells 0.62
Gene expression profiling of neural crest progenitor cultures derived from human embryonic stem cells carrying nonsense mutations in the Polycomb gene ASXL1 0.62
Genome-wide expression analysis of human hTert immortalized fibroblasts after downregulation of MCM2 & MCM7 0.57
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.55
EGR1-controlled transcriptome of T HESCs 0.54
Zika virus directly infects human peripheral neurons and induces cell death 0.5
The control of rRNA synthesis during the directed differentiation of human embryonic stem cells precedes heterochromatin formation. 0.47
High-resolution comparative analysis of great ape genomes 0.47
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 0.47
Integrated high-throughput screen to identify novel treatment leads for pediatric acute myeloid leukemia (AML) 0.45
Genome-wide analyses of chromatin state in human mast cells reveal molecular drivers and mediators of allergic and inflammatory diseases 0.44
Transcriptomic profiling of human peripheral blood-derived mast cells 0.44
Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the TBX2 Subfamily of Tumor Suppressor Genes 0.44
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 0.44
Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures 0.41
Small-molecule-based Human Genome G4 Profiling Reveals Potential Gene Regulation Activity 0.37
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 0.35
RNA-seq analysis of PRMT5-regulated genes in irradiated/non-irradiated LNCaP cells 0.35
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.33
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.33
RNA-seq of HUVEC ± shRNA knockdown of SENCR 0.31
Novel SF3B1 Deletion Mutations Result in Aberrant RNA Splicing in CLL Patients 0.31
In search for materials able to be colonized by a normal endothelium: сharacterization and NGS gene expression profiling of human primary endotheliocytes cultivated on electrospun 3D matrices 0.3
single cell RNA-seq from Purkinje cell (ENCSR888LYA) 0.29
Antiviral and anti-inflammatory properties of novel anti-HIV candidate ABX464 promotes specifics RNA splicing while preserving cellular RNA integrity. 0.28
Human pulmonary artery endothelial cells (hPAECs) with downregulated BMPR2 signaling demonstrate a unique gene expression signature after exposure to overexpression of AdAlox5 0.27
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 0.25
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 0.19
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 0.17
Transcriptomic profiling of sequential tumours from breast cancer patients provides a global view of metastatic expression changes following endocrine therapy 0.17
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 0.14
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 0.12
hsa-miR-503, hsa-miR-103, and hsa-miR-494 genome wide target profiles [RNA-Seq and RIP-Seq] 0.11
Genome-wide hsa-miR-503, hsa-miR-103, and hsa-miR-494 target profiles 0.11
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability] 0.1
Modulation of nonsense-mediated decay by rapamycin 0.09
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 0.08
Functional Inflammatory Profiles Distinguish Myelin-Reactive T Cells from Patients with Multiple Sclerosis 0.07
RNA sequencing of hiPSC derived neural crest populations from Familial Dysautonomia patients 0.05
SOX11 knockdown in B-ALL cell lines 0.01
Transcriptome analysis of fetal Klinefelter testis tissue samples compared to controls 0.0


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