Gene Query: UPF3A

Dataset Description Geneva Score
MeRIP sequencing reveals angiogenic properties of vascular endothelial cells 43.23
Treatment of multiple myeloma cells with EZH2 small molecule inhibitor 42.35
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma 23.17
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 22.98
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer 18.63
Gene target specificity of the Super Elongation Complex (SEC) family: How HIV-1 Tat employs selected SEC members to activate viral transcription 18.38
Identification of genes regulated by Long noncoding RNA H19 in hepatic cells 17.72
H19 regulates hepatic glucose production by epigenetic modification of Hnf4* 17.72
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 16.65
Cancer avatars derived from genetically engineered pluripotent stem cells allow for longitudinal assessment of tumor development 15.01
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 14.66
A common cell state in Triple Negative Breast Cancers represents a druggable vulnerability 14.3
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors 14.19
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors [RNA-seq] 14.19
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 13.98
Dual modulation of neuron specific microRNAs and the REST complex promotes functional maturation of induced human adult neurons 13.9
mRNA and RNC-mRNA deep sequencing of three hepatocellular carcinoma cell lines 13.43
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 13.31
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 13.31
Time-Resolved Proteomics Extends Ribosome Profiling-Based Measurements of Protein Synthesis Dynamics 12.96
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 12.55
Cleavage Factor Im as a key regulator of 3’ UTR length 12.51
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 12.49
Transcriptome wide identification of Dicer binding in human and C. elegans reveals a variety of substrates 12.37
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma (RNA-Seq) 11.72
High resolution ChIP sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma 11.72
Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed 11.36
RNA sequencing of human mammary epithelial cells 11.31
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 11.06
Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes 10.64
SAM68 is required for regulation of Pumilio by the NORAD long noncoding RNA 10.62
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 10.54
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 10.53
3D genome of multiple myeloma reveals spatial genome disorganization associated with copy number variations 10.49
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 10.47
Transcriptome Profiling Reveals the key genes and pathways involved in polycystic ovary syndrome [RNA-seq] 10.45
Identification of epigenetic interactions between miRNA and DNA methylation associated with polycystic ovarian syndrome 10.45
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 10.3
Improved genome-wide mapping of uncapped and cleaved transcripts in eukaryotes—GMUCT 2.0 10.29
Gene expression analysis of the impact of TDP-43 knockout in human cells. 9.99
mRNA-sequencing of U87 glioblastoma and DAOY medulloblastoma spheroidal aggregates undergoing electrotaxis 9.94
Gene expression changes associated with resistance to tagraxofusp (SL-401) 9.93
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 9.92
Global transcriptional changes in U87MG glioblastoma cells upon shRNA-mediated TRIM52 knockdown 9.91
Genome-scale screens identify JNK/JUN signaling as a barrier for pluripotency exit and endoderm differentiation 9.82
RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures 9.77
Sequencing Universal Human Reference RNA by Smart-seq and early barcoding library preparation methods 9.37
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 9.29
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 9.18
IL-33 activates tumor stroma to promote intestinal polyposis 9.17
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 9.05
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 8.99
The evolution of N6-methyladenosine in primates 8.89
Transcriptomic profiling of O-GlcNAcylated mRNA-protein complexes by using OG-CLAP in HeLa cells. 8.78
Mitochondrial phosphoenolpyruvate carboxykinase (PCK2) regulates metabolic adaptation and glucose-independent tumor cell growth 8.6
Adaptive chromatin remodeling in glioblastoma stem cell plasticity and drug tolerance 8.57
ONECUT2 Drives Neuroendocrine Prostate Cancer Through Hypoxia Signaling 8.54
Identifying ASCL1 target genes in primary GBM stem cell cultures [RNA-seq] 8.5
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 8.33
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response 8.31
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 8.08
Gene expression changes in THP1 cells at day 2 and 4 following shRNA knock-down of RUVBL2 8.03
Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells 8.02
Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing 7.9
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 7.86
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 7.82
Differentiation enhances Zika virus infection in neuronal brain cells 7.79
Post-transcriptional manipulation of TERC reverses molecular hallmarks of telomere disease 7.74
Meta-organization of Translation Centers Revealed by Proximity Mapping of Endoplasmic Reticulum Ribosome Interactors 7.7
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 7.66
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 7.54
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 7.54
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 7.54
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype [RNA-Seq] 7.5
Bromodomain-containing Protein 4 (BRD4) is Required for the Maintenance of a Mammary Epithelial Phenotype 7.5
CROP-Seq in Primary Human T Cells 7.44
Integrating single-cell transcriptomic data across different conditions, technologies, and species 7.4
Total RNA sequencing of prospective axial stem cell cultures derived from human pluripotant stem cells 7.39
Transcriptome analysis of total RNA in human osteosarcoma cell line U2OS before and after inhibition of zinc finger protein ZNF768 7.37
Synaptic dysfunction in human neurons with Autism associated deletions in PTCHD1-AS 7.32
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 7.19
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer [RNA-Seq] 7.17
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 7.16
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 7.12
Fibroblasts in cholesteatoma activate osteoclasts. 7.09
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer 7.08
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 7.07
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration 7.07
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development [set 1] 7.06
Epigenomic landscape during organ formation in human early embryos 7.05
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 7.04
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Human_RWPE1_RNA-Seq) 6.97
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation 6.97
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 6.93
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 6.89
Epigenetic Inactivation of Cysteine Dioxygenase Type 1 Contributes to ROS-dependent Progression of Colorectal Cancer 6.86
Next Generation Sequencing Facilitates Quantitative Analysis of ALDH+ E-BCSC, CD24-CD44+ M-BCSC and Bulk tumor cell Transcriptomes from MC1 and Vari068 PDX models of TNBC 6.84
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 6.82
Identification of elevated A-to-I editing sites due to expression of an active ADAR3 mutant in human glioblastoma cells 6.8
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 6.79
IL-6/Stat3-Dependent Induction of Distinct, Obesity-Associated Natural Killer Cells Deteriorates Energy and Glucose Homeostasis 6.79
RNA-seq, ChIP-seq and single cell RNA-seq of human skin Langerhans cells 6.78
Genome-Wide Transcriptional Effects of the Anti-Cancer Agent Camptothecin 6.72
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia 6.72
Accurate annotation of human protein-coding small open reading frames 6.66
Toxicogenomics of the flame retardant tris (2-butoxyethyl) phosphate in HepG2 cells using RNA-seq. 6.65
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 6.62
Differential expression of human parthenogenic stem cells, neural stem cells and DA progenitors. 6.5
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 6.44
Human Pancreatic Islets Expressing HNF1A Variant Have Defective β cell Transcriptional Regulatory Networks 6.44
Short-term effect of Boost versus Radical doses of Intraoperative electron Radiotherapy in breast cancer tumor bed using high-throughput approaches 6.42
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 6.4
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression 6.39
Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression [RNA-Seq] 6.39
scRNASeq analysis of cycling cardiomyocytes 6.35
Survival of pancreatic cancer cells lacking KRAS function 6.31
N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis [RNA-Seq] 6.3
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 6.24
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 6.24
Exploring transcriptomic landscapes in red cell populations, in their extracellular vesicles and on single cell level 6.22
RNA-seq of human aneuploid cell lines with Trisomy 21 6.22
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 6.17
Transcriptional effect of ETV1 knockdown in melanoma cells 6.15
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [cPDS-RNA-seq] 6.14
Species-specific maturation profiles of human, chimpanzee and bonobo neural cells 6.12
De novo reconstruction of human adipose reveals conserved lncRNAs as regulators of brown adipogenesis 6.08
Synergy from Gene Expression and Network Mining (SynGeNet) method predicts genotype-specific synergistic drug combinations in melanoma 6.07
In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity 6.06
Expression data from fresh human embryonic lung epithelial tip and stalk cells and cultured organoids derived from tip and stalk. 6.01
Gene expression in control and DOCK8 CRISPR KHYG1 NK cells 6.01
Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution 5.96
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 5.96
MYT1 attenuates neuroblastoma cell differentiation by inhibiting retinoic acid signaling pathway 5.96
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 5.96
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 5.88
DJ-1 is dispensable for human stem cell homeostasis 5.86
RNA-Seq in two Ewing sarcoma cell lines: A673 and SKNMC 5.76
Poly(ADP-ribosyl)ation dependent changes in CTCF-chromatin binding and gene expression in breast cells 5.69
Paired Related Homeobox Protein 1 Regulates Quiescence in Human Oligodendrocyte Progenitors 5.69
Effects of Polybrominated Diphenyl Ether (PBDE) Mixture on estrogen receptor positive (ER+) patient-derived tumor xenograft (PDX) model 5.68
hTERT promotes cell adhesion and migration independent of telomerase activity 5.68
METTL3 promotes translation in human cancer cells 5.66
Gene expression profiling of leukemia cells following asparagine depletion 5.66
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 5.65
DECIDUALIZATION INDUCES A SECRETOME SWITCH IN THE PERIVASCULAR NICHE CELLS OF THE HUMAN ENDOMETRIUM 5.64
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling 5.62
TRIM28-Regulated Transposon Repression Is Required for Human Germline Competency and Not Primed or Naive Human Pluripotency 5.61
The comparison of high-throughput single-cell RNA-seq methods 5.58
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 5.55
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 5.53
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros 5.5
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 5.5
Rorc disruption in human FG pancreatic cancer cells 5.48
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation 5.46
Transcriptional profiling of LS1034 cells treated with tepoxalin 5.39
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 5.39
Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors 5.38
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not 5.35
Gene expression in GBM with Cav3.2 inhibition 5.34
Global analysis of enhancer targets: Mosaic-seq 5.34
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 5.3
Differetially expressed genes after hTR overexpression in U2OS cells 5.28
Role of FGFR1 in neuronal devlopment 5.25
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 5.22
Patient-derived luminal breast cancer xenografts with progestins 5.22
Transcriptomic analysis of the HOTAIR-regulated genes 5.22
MYC dependent mRNA translation shapes gene expression and cell biology 5.18
Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression 5.17
Transcriptome-wide response to synthetic chromatin protein PcTF 5.16
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq 2] 5.15
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 5.14
RNA-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 5.11
RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 5.11
Selective modulation of inflammatory Natural Killer (NK) cell phenotypes following histone H3K27 demethylase inhibition [RNA-Seq] 5.11
Selective modulation of inflammatory Natural Killer (NK) cell phenotypes following histone H3K27 demethylase inhibition 5.11
The age and genomic integrity of neurons after cortical stroke in humans 5.11
RNA-sequencing 5.1
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 5.09
Characterization of sperm lncRNA and its differently expression in the sperm of asthenozoospermic patients 5.09
RNA-Seq analysis of Head and Neck Squamous cell carcinoma cell-lines 5.06
Genome expression analysis of Lung Progenitors matured in the presence of constitutively active or pharmacologically inhibited Glycogen Synthase Kinase 3 5.05
Altering cancer transcriptomes using epigenomic inhibitors [RNA-Seq] 5.03
Altering cancer transcriptomes using epigenomic inhibitors 5.03
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 5.02
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [MB157_RNA-seq] 5.02
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 5.01
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with tcons_00001221 shRNA or control shRNA 5.0
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 4.98
RNA sequencing of BT142 and TS603 cell lines 4.98
Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas 4.98
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 4.98
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 4.95
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes 4.95
Global transcriptional profiling changes upon knockdown of LKB1 in human glioblastoma cell lines 4.94
Gene expression analysis of BRD4 knockdown in HT-29 and HCT116 cells 4.92
Chronic Myeloid Leukemia (CML), induced pluripotent stem cell (iPSC)-derived lin-CD34+CD45+ (iCD34) cell population 4.91
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 4.9
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia [scRNA-seq] 4.87
Chromatin mapping and single-cell immune profiling defines the temporal dynamics of ibrutinib drug response in chronic lymphocytic leukemia 4.87
RNA-seq analysis of YFV-17D specific and total naive CD8 T cells in humans 4.87
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 4.85
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 4.83
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 4.83
Medial Ganglionic Eminence and Cortical Organoids Model Human Brain Development and Interneuron Migration 4.8
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 4.8
Transcriptome analysis of BAP1 knockout and restoration 4.8
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 4.74
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 4.74
Improved post thaw function and genetic changes for mesenchymal stromal cells cryopreserved using multicomponent osmolyte solutions 4.66
Functional Screening in Human Cardiac Organoids Reveals a Metabolic Mechanism for Cardiomyocyte Maturation 4.65
SERPINA3- a novel keratinocyte differentiation promotor mediates epidermal barrier repair response in psoriatic lesion 4.64
RNA seq data of Hep3B-control, Hep3B-sertraline, Hep3B-XL413, Hep3B-XL413-sertraline, Huh7-control, Huh7-sertraline, Huh7-XL413, Huh7-XL413-sertraline cells 4.6
Gene expression changes after depletion of Cyclin F and atypical E2Fs in HeLa cells. 4.59
Direct Isolation and Characterization of Human Nephron Progenitors. 4.58
Single-cell analysis reveals stochastic regulation of type I IFN production by plasmacytoid dendritic cells and identifies host-derived environmental cues as amplifier of type I IFN production 4.51
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 4.51
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 4.46
Potent antitumor activity of Cabozantinib, a c-MET and VEGFR2 Inhibitor, in a Colorectal Cancer Patient-derived Tumor Explant Model 4.46
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 4.45
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 4.45
Sequencing of messenger RNAs with N6-methyladenosine modifications in acute myeloid leukemia (AML) with and without forced expression of FTO 4.42
Folliculin regulates mTORC1/2 and WNT pathways in early human pluripotency 4.35
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer 4.3
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer [RNA-seq] 4.3
RNA sequencing of heart samples of myotonic dystrophic (DM1) patients 4.3
Gene expression changes caused by KRAS in MCF-10A 4.26
Gene expression analysis upon mtDNA depletion 4.23
Gene expression analysis upon mtDNA depletion [RNA-seq] 4.23
Similarity of therapeutic networks induced by a multi-component herbal remedy in neurovascular unit cells 4.21
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 4.19
Global response to chemotherapy-induced apoptosis 4.18
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 4.17
Comparative gene expression profiling of MHH-CALL4 cells subject to pharmacological JAK2 inhibitor treatment (ruxolitinib or CHZ868) or shRNA-mediated JAK2 depletion in vitro 4.16
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias 4.16
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 4.07
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors 4.06
CD86 regulates a pro-survival signal in myeloma cells 4.01
Effect of BCL11B overexpression on transcriptome of T-cell acute lymphoblastic leukemia (T-ALL) cells 3.97
Dysregulated immune system networks in war veterans with PTSD 3.96
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq] 3.96
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 3.94
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 3.92
Inhibition of ERG Activity in Patient Derived Prostate Cancer Xenografts using the Small Molecule Inhibitor YK-4-279 3.89
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 3.87
Generation and persistence of human tissue-resident memory T cells in lung transplantation 3.84
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 3.76
CD90 Identifies Adventitial Mesenchymal Progenitor Cells in Adult Humans 3.74
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 3.71
Single-cell RNA sequencing-based CRISPRi screening resolves molecular drivers of early human endoderm development 3.71
Enhancement of Arterial Specification in Human Pluripotent Stem Cell Cultures Promotes Definitive Hematoendothelial Program with Broad Myelolymphoid Potential 3.62
Transcriptome of Stabilin-1 siRNA transfected human monocytes 3.61
Transcriptome changes due to nuclear penetration of cancer extracellular vesicles 3.59
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 3.55
Universal alternative splicing of noncoding exons 3.55
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells [RNA-seq] 3.54
JMJD3 and UTX Determine Fidelity and Lineage Specification of Human Neural Progenitor Cells 3.54
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 3.53
Identification of renal resident macrophages across species 3.53
single cell RNA-seq from GM12878 (ENCSR673UIY) 3.52
SLIGRL-induced gene expression changes in NHEK cells 3.48
Histone Demethylases KDM3A and KDM4C regulate mesenchymal stromal cell senescence and bone aging through condensin-mediated heterochromatin organization 3.42
Control of gene expression in senescence through transcriptional read-through of convergent protein-coding genes 3.37
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability 3.32
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability [RNA-seq] 3.32
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5’ and 3’ Ends of Genes 3.32
MiR-26 dampens IL-6 production by down-regulating TNF-a/NF-kB signaling through silencing HMGA1 and MALT1 and not by directly targeting IL-6 mRNA 3.31
RNA sequencing analysis of selumetinib-resistant CRC cells lines 3.31
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines [RNA-seq] 3.25
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines 3.25
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (ChIP-seq & RNA-seq datasets) 3.25
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 3.25
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 3.22
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation 3.2
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation (RNA-Seq) 3.2
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 3.17
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL [RNA-seq] 3.13
Genetic analysis of Ikaros target genes and tumor suppressor function in BCR-ABL1+ pre-B ALL 3.13
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 3.11
SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate 3.11
Transcriptomic analysis of LSD1 3.09
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 2.98
RNA-Sequencing data of Varicella Zoster Virus (VZV)-infected human dermal fibroblasts (HDF) 2.93
The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC derived cardiomyocytes. 2.92
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo 2.91
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo [RNA-seq] 2.91
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells (RNA-seq) 2.87
PLZF targets developmental enhancers for activation during osteogenic differentiation of human mesenchymal stem cells 2.87
RNA-seq in HT-29 colorectal cancer cells after F. nucleatum treatment 2.86
IMP3 regulated gene expression in breast cancer cells 2.85
EP400 is required for Max and MCPyV mediated gene activation 2.83
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 2.83
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 2.83
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 [3mRNA-seq] 2.83
Identification of renal resident macrophages across species [C1] 2.8
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 2.78
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 2.78
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 2.78
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 2.78
Molecular Criteria for Defining the Naive Human Pluripotent State 2.77
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 2.77
Capturing the Interactome of Newly Transcribed RNA 2.77
Capturing the Interactome of Newly Transcribed RNA (RICK) 2.77
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion 2.74
Single-cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment - 5' RNA sequencing and TCR sequencing 2.74
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 2.71
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 2.68
Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria 2.66
N6-methyladenosine (m6A) profiling of EndoC-bH1 cell line and RNA seq of Mettl14 knockout mice beta cell 2.65
The transcriptome and chromatin accessbility landscape of mammalian germline 2.64
Hepatocyte maturation 2.61
mRNA sequencing of highly and lowly metastatic human colorectal cancer PDXs 2.56
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 2.54
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 2.53
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier [human] 2.53
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier 2.53
Class I histone deacetylases HDAC1, 2 and 3 are histone decrotonylases 2.53
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 2.5
Transcriptome response to 4h IL-1b stimulation of primary chondrocytes 2.44
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 2.37
Transcriptional profiling of microglia; current state of the art and future perspectives 2.33
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 2.32
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 2.32
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid [TEMRA] 2.3
Clonally expanded CD8 T cells patrol Alzheimer's cerebrospinal fluid 2.3
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 2.29
An integrative analysis of non-coding regulatory DNA variations associated with autism 2.28
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 2.24
4sUDRB-seq: measuring transcription elongation and initiation genomewide 2.22
High-throughput single cell transcriptome analysis and CRISPR screen identify key β cell-specific disease genes 2.22
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples 2.19
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity 2.18
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 2.17
Identification of Atrial Fibrillation associated genes and functional non-coding variants 2.17
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans 2.14
Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans [human scRNA-seq] 2.14
Expression analysis of THP1 cells following shRNA knock-down of RUVBL2 2.12
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile [mRNA-Seq] 2.05
Transcriptome analysis of reticulated platelets reveals a prothrombotic profile 2.05
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 2.05
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 2.04
Identification of transcripts altered upon LIN-41 knockdown in human embryonic stem cells 2.04
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 2.02
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 2.01
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 2.01
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 2.01
ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex 1.97
Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome 1.97
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 1.95
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 1.94
The transcriptomic landscape of MAIT cell development in the thymus (NN41 RNAseq data set) 1.93
Comparative Transcriptomic Analysis of Hematopoietic System Across Species by Microwell-Seq 1.91
Ex vivo Dynamics of Human Glioblastoma Cells in a Microvasculature-on-a-Chip System Correlates with Tumor Heterogeneity and Subtypes 1.9
RNA-seq of cultured human kidney peritubular microvascular endothelial cells following exposure to cyclosporine A 1.89
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 1.88
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers (RNA-Seq) 1.87
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers 1.87
Subtle asymmetry of gene expression in embryonic and foetal human brains 1.83
Neuronal Development And The Onset Of Electrical Activity In The Human Enteric Nervous System 1.8
Methylome, hydroxymethylome, and integrative transcriptome profiling in human CRC tissue and paired normal tissues 1.77
mRNA expression profiling in MDA-MB-231 (LM1) cells with a tet-incible MBD2 or p66α knock down, or treated with MBD2-targeting small molecule ABA or APC 1.76
A compendium of promoter-centered long-range chromatin interactions in diverse human tissues and cell types 1.73
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons 1.72
NOTCH signaling is activated in and contributes to resistance in enzalutamide-resistant prostate cancer cells 1.68
Transcriptome of EBV-infected gastric cancer cell lines 1.64
A novel target of EZH1/2 for treatment of mantle cell lymphoma 1.6
Epigenomic conservation of transposable element silencing 1.59
Epigenomic conservation of transposable element silencing [RNA-seq] 1.59
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 1.59
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 1.57
Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program 1.54
Transcriptional repression in hypoxia is mediated by the Sin3A histone deacetylase complex [RNA-seq] 1.52
The Cushing's disease adipose gene expression profile reveals effects of long term glucocorticoids on adipose tissue lipid, protein and glucose metabolism 1.52
RNA-seq of human foreskin fibroblast cells lacking RB, p130, and p107 treated with doxorubicin. 1.51
Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence. 1.51
Human Treg IL-12 stimulation 1.48
Genetic and Epigenetic Landscapes of Laterally Spreading Tumors of the Colorectum 1.45
RNA sequencing of T-ALL (COG study) 1.44
Analyses of T-ALL (COG study) 1.44
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses 1.41
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 1.4
Transcriptomic analysis of cultured corneal endothelial cells as a validation for their use in cell-replacement therapy 1.36
RNA-seq analysis of primary patient samples to characterize the CNS leukemia 1.35
Transcriptome analysis of CNS leukemia 1.35
Total RNA-Seq data from leukemic patients with complex structural variants 1.35
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 1.34
Functional separation of IL7Rα/KLRG1-defined CD8+ T cell populations in humans 1.33
Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis 1.32
UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation 1.3
Immunoglobulin transcript sequence and somatic hypermutation computation from unselected RNA-seq reads in Chronic Lymphocytic Leukemia 1.23
mRNA expression in iPS cells generated by a synthetic self-replicative RNA 1.21
SNHG5 siRNA knock down in HCT116 cells 1.18
RNA seq analysis of human Fetal and adult derived Enterospheres 1.18
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 1.18
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 1.18
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis 1.15
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis [RNA-Seq] 1.15
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 1.14
Iron response of HepG2 cells 1.13
Dissecting cell composition and cell-cell interaction network of human disease heart tissue by single-cell sequencing 1.12
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 1.1
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 1.1
RNA sequencing of Formalin-Fixed, Paraffin-Embedded Specimens for Gene Expression Quantification and Data Mining 1.08
Gene expression profiling associated with knockdown of LKB1 in human intrahepatic cholangiocarcinoma 1.07
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 1.05
BMS-470539 on human synovial fibroblasts 1.03
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [mutant MEF2C] 1.02
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells [RNA-Seq] 1.01
A novel transcriptional network for the Androgen Receptor in human epididymis epithelial cells 1.01
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells 1.0
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells [GRO-seq] 1.0
CD48-dependent protective autophagy in conventional human T cells promotes restimulation-induced cell death resistance 1.0
RNA-Sequencing of human dermal lymphatic endothelial cells (HDLEC) treated with siRNA targeting YAP/TAZ and YAP5SA 0.97
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 0.96
RNA Expression Profile of Calcified Bicuspid, Tricuspid and Normal Human Aortic Valves by RNA Sequencing [TAV] 0.95
Functional astrocytes differentiated from hiPSCs 0.95
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 0.93
RNA-sequencing of healthy human skeletal myocytes 0.93
Transcriptomic analysis of inter- and intra-patient variation in human iPSC cardiomyocytes: Platform for precision medicine to predict drug toxicity 0.91
Transcriptomic profile of intestinal epithelial cells obtained from ileal endoscopic biopsies from newly-diagnosed, pediatric Crohn's disease patients and healthy controls. 0.89
RNA-sequencing analysis of 5' capped RNAs identifies novel differentially expressed genes in sessile serrated colon polyps (SSPs) 0.89
A novel non-canonical signaling pathway mediates TGF-β1-induced glucocorticoid insensitivity in epithelial cells 0.88
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 0.86
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.85
Transcription factors and stress response gene alterations in human keratinocytes following Solar Simulated Ultra Violet Radiation 0.85
CD161+ Tconv and Treg share transcriptome and display a migratory phenotype which is modified at the inflamed site 0.83
CRISPR/Cas9 Screens Reveal Epstein-Barr virus Synthetic Lethal Targets 0.82
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.74
Impact on erythroid progenitor type on erythroid differntiation 0.74
Transcriptome analysis in a radiosensitive and a radioresistant cell line after ionizing radiation 0.74
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 0.72
A Phase II Study of Pomalidomide, Daily Low Dose Oral Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma 0.7
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 0.69
A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation 0.67
TALEN-based knockout of mir-141 and mir-200c in SK-BR-3 cells 0.66
Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma 0.65
RNA-Seq profiling of iPSC-derived ventricular and atrial cardiomyocytes 0.62
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 0.62
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 0.6
Expression of MERTK based on Multiple Sclerosis (MS) risk haplotype 0.59
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 0.58
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine [RNA-Seq] 0.58
Expression data for HT29 cells treated with 5-aza-deoxy-cytidine 0.58
The control of rRNA synthesis during the directed differentiation of human embryonic stem cells precedes heterochromatin formation. 0.55
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 0.53
The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner 0.51
Self-associated molecular patterns mediate cancer immune evasion by engagement of Siglec receptors 0.49
CRISPR/Cas9-mediated ASXL1 mutation in U937 cells perturbs myeloid differentiation 0.49
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 0.48
Next Generation Sequencing Facilitates Comparisons of Control and Schizophrenia-Patient derived hiPSC-derived NPCs 0.47
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 0.44
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells 0.43
Human stem cell based models of neuronal migration provide insight into neurological disease pathogenesis and potential treatment 0.43
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 0.41
RNAseq of CD8+ and CD8- MAIT cells in human peripheral blood 0.4
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 0.4
Expression profile of MM.1S tumors folloiwing treatment with bortezomib 0.4
Function and hormonal regulation of GATA3 in human first trimester placentation 0.39
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 0.39
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.38
RNA-sequencing of bulk CD19+ Thymic B cells from young (3 month - 4 year) and old (42 - 61 years) humans 0.37
RNA-sequencing of bulk CD19+ Thymic B cells from mice and humans 0.37
Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles 0.36
Genome-wide mapping of TEL-AML1 targets in acute leukemia 0.35
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of HSCe) 0.35
Zoledronic acid inhibits NFAT and IL-2 signaling pathways in regulatory T cells and diminishes their suppressive function in patients with metastatic cancer 0.33
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.3
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.3
Functional and genomic characterization of a xenograft model system for the study of metastasis in triple-negative breast cancer. 0.27
Metastasis in triple-negative breast cancer 0.27
FOXO1 is an oncogenic mediator in AML1-ETO leukemia 0.26
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG functional reactivation [human cells RNA-seq] 0.25
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG 0.25
Musashi-2 attenuates AHR signalling to expand human haematopoietic stem cells 0.25
Platelet Transcriptome Profiling in HIV and ABCC4 as a Biomarker of Platelet Activity 0.24
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 0.23
Induction of Cardiomyocyte Proliferation [pz-822_human] 0.23
Longitudinal transcriptome profiling of post-treatment Lyme disease syndrome 0.22
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 0.2
MHC Transcriptomic landscape at haplotype-specific resolution 0.19
RNA-seq and small RNA-seq from WT and ADAR1 knockdown H9 lines and their differentiation to specific types of neurons 0.19
Genome-wide effect of inhibition of glutamine transporter ASCT2 in PC-3 cells by BenSer or GPNA 0.18
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 0.17
RNAseq data from Mesenchymal stem cells treated with TCDD or 1-methyl tryptophan 0.16
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles 0.15
CX3CR1/Fractalkine receptor expression separates memory CD8+ T cells with distinct functional profiles (RNA-seq) 0.15
The lung-enriched p53 mutants V157F and R158L/P regulate a novel transcriptome in lung cancer 0.14
Gene expression profile of calcified and normal tricuspid aortic valves by RNA sequencing. 0.13
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 0.11
Primate-specific gene TMEM14B promotes cortical expansion and folding 0.11
Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements 0.11
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 0.09
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 0.09
Downregulation of LATS kinases alters p53 to promote cell migration 0.06
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. 0.05
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. [RNA-Seq] 0.05
Characterizing the Chemoresistant Ovarian Cancer Population using the Heterogeneous PDX 0.05
Gene expression activation in CLL mediated by MSCs contact 0.03
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 0.02
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.01
Genome-wide profiling of cervical RNA-binding proteins identified HPV regulation of RNASEH2A expression by viral E7 and E2F1 0.01


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