Gene Query: USP1

Dataset Description Geneva Score
CD95L derived si- and shRNAs and the CD95L mRNA kill cancer cells through an RNAi mechanism by targeting survival genes [siL3.RNAseq.lg] 73.57
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 70.14
Triplet nucleotide repeat-based siRNAs are highly toxic to cancer cells 49.05
Homolog-selective degradation as a strategy to probe the function of CDK6 in AML 45.33
Comparison of single-cell transcriptomics quality between unfixed cells and cells that were fixed and mock stained according to the RAID procedure 44.14
MDM2 and MDM4 are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors 43.73
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 39.71
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 39.71
Genome wide transcriptome analysis of palbociclib or GSK3326595 treated A375 cells [Palbociclib_GSK_RNASeq] 38.72
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 38.32
NAD+ Analog-sensitive PARPs Reveal a Role for PARP-1 in Transcription Elongation 37.28
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 35.84
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 35.84
Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation 33.87
Gene expression profiles in response to proanthocyanidins in pancreatic cancer cells 33.77
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 33.6
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 31.46
HOXC6 affects the malignant phenotype of esophageal squamous cell carcinoma cells 29.18
Genes significantly down or Up-regulated upon RNF219 knockdown 28.38
Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies 27.69
Seletive inhibition of CDK9 in DLBCL cell lines 26.83
Genome-wide transcriptional response to random aneuploidy in human cells 26.25
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 26.13
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 26.03
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 26.03
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 25.52
Human cell line and subcutaneous tumor 25.4
Changes in RNA expression in human oral cavity carcinoma cells as a result of LDB1 reduction 25.34
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 25.24
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (chromatin-bound RNA-seq) 24.9
A Hybrid Mechanism of Action for BCL6 in B Cells Defined by Formation of Functionally Distinct Complexes at Enhancers and Promoters 23.99
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with ENST00000431060 shRNA or control shRNA 23.7
The p30 isoform of CEBPA uncovers a silent enhancer to drive the expression of the tumor promotive factor CD73 in CEBPA mutant AML 23.51
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 23.23
RNA expression analysis of neuroblastoma cell lines treated with epigenetic drugs 22.93
Transcriptomic analysis of primary human T cells and murine RAW 264.7 macrophages 3D cultured in different collagen densities 22.5
Transcriptome analysis of total RNA in human osteosarcoma cell line U2OS before and after inhibition of zinc finger protein ZNF768 22.41
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 21.9
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation [RNA-Seq] 21.66
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 21.19
Limiting cholesterol biosynthetic flux engages type I IFN signaling in a STING-dependent manner 21.17
High-throughput sequencing of PROMPT-enriched samples. 20.85
ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state 20.56
Implication of Long noncoding RNAs in the endothelial cell response to hypoxia revealed by RNA-sequencing. 20.46
A code of mono-phosphorylation modulates the function of RB. 20.4
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 20.38
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (human 3' mRNA-seq) 20.01
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 19.96
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 19.51
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 19.51
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 19.51
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 19.48
Epigenome-wide Effects of Vitamin-D on Bronchial Epithelial Cells using ATAC-Seq and RNA-seq 19.46
Transcriptome analysis of Jurkat T-ALL clones from control and CBAP-knockdown/knockout sets 19.22
Ribosomal footprinting of CN34-Parental and CN34-LM1a 19.02
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 18.94
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 18.9
RNA Sequencing Reveals Immunosuppressive Role of Anthrax Lethal Toxin in Human Lung Epithelial and Monocytic Cells 18.66
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 18.58
Transcriptome analysis of BAP1 knockout and restoration 18.58
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 18.43
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 18.38
RNA sequencing (RNA-SEQ) of Human endothelial cells (HUVEC) in LFS, sFRP2OE, and WT conditioned media 18.16
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 18.05
Ribosomal footprinting of MDA-Parental and MDA-LM2 18.04
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 17.68
Gene expression profile of human multiple myeloma cell line MM.1S after knockdown of KDM6B 17.56
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 17.47
Chromatin accessibility landscape upon induction of Msgn1, Pax3 and Myf5 in mesodermal cells and identification of conserved Pax3 binding sites and target genes during skeletal myogenesis 17.4
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling [RNA-seq] 17.33
The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling 17.33
ETS1 acts as a tumor suppressor in breast cancer by inhibiting growth-related factors 17.09
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidgenic proteins 16.92
EGR1-controlled transcriptome of T HESCs 16.91
Differential responses by human respiratory epithelial cell lines to respiratory syncytial virus reflect distinct patterns of infection control 16.75
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 16.69
Transcriptional profiles of normal human mature B cells 16.49
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 16.47
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 16.47
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 16.38
Differential roles of human PUS10 in miRNA processing and tRNA pseudouridylation 16.25
Identification of Nrf2 regulated genes by RNA sequencing 16.23
Nrf2 regulated genes in A549 cells 16.23
Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases 16.0
Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation 15.94
Fbxo32 mediated gene expression program underlies EMT and metastasis 15.88
Overexpression and knockdown experiment for circCSNK1G3 15.82
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 15.68
Toxoplasma gondii remodels the cis-regulatory landscape of infected human host cells [RNA-seq] 15.66
Toxoplasma gondii remodels the cis-regulatory landscape of infected human host cells 15.66
RNA transcriptome analysis during HSV-1 infection 15.63
Genome models integrating chromatin contacts and nuclear lamin-genome interactions reveal implications of laminopathy-causing lamin mutations on genome architecture 15.54
RNASEQ Analysis of sh-TRC and sh-MIR100HG in the triplex negative breast cancer 15.5
Exploring transcriptomic landscapes in red cell populations, in their extracellular vesicles and on single cell level 15.41
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 15.33
3’ Uridylation Expands miRNA Target Repertoire 15.27
Elucidating the microRNA-203 specific biological processes in glioblastoma cells from comprehensive high-throughput RNA-sequencing transcriptome profiling 15.24
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 15.12
Effect of drugs on transcriptomic profiles 15.11
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell 15.04
RNA-seq analysis to identify the genes regulated by p53-SET interplay 15.01
Novel Targeting of Transcription and Metabolism in Glioblastoma 14.89
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 14.89
COMBINING BET AND MEK INHIBITORS SYNERGISTICALLY TARGETS NRAS MUTANT MELANOMA 14.88
Genome-wide analysis of YAP and TFCP2 occupancy and regulated expression in liver cancer cells 14.86
Genome-wide analysis of YAP and TFCP2 down-regulated genes in liver cancer cells 14.86
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 14.82
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 14.82
Identification of Sin3B regulated genes during quiescence 14.8
Differential expression analysis of RNA-seq data from melanocytes driven by tumor cell-derived exosomes 14.71
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 14.68
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 14.68
Simultaneous quantification of antibody-RNA conjugates and the transcriptome from fixed cells by RAID 14.48
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 14.37
Global Mapping of Human RNA-RNA Interactions 14.33
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 14.26
Long non-coding RNAs are central regulators of the IL-1b-induced inflammatory response in human lung fibroblasts 14.02
FOXD3 is a novel tumor suppressor in lung cancer 14.0
Ribosomal footprinting of MDA_Ctrl and MDA_Arg overexpression cell lines 14.0
E2F1 orchestrates transcriptomics and oxidative metabolism in Wharton’s jelly derived mesenchymal stem cells from growth-restricted neonates 13.99
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure by siRNA knockdown of Anillin [tpo8] 13.98
JQ1 +/- Vemurafenib in BRAF mutant melanoma (A375) 13.93
SLAM-seq for K562 endogenous mRNA decay 13.87
Presence of NAD+-capped RNA in human cells: function and removal by the DXO deNADing Protein 13.86
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development 13.84
Transcriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq] 13.84
Alu RNA modulates the expression of cell cycle genes in human fibroblasts 13.81
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on PANC1 cells treated with CoCl2) 13.78
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 13.69
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 13.67
Tristetraprolin disables prostate cancer maintenance by impairing proliferation and metabolic function 13.58
WNK1 kinase and the termination factor PCF11 connect nuclear mRNA export with transcription 13.45
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 13.36
HIV-1 perturbs homeostatic ILCs, unmasks ILC1 plasticity, and boosts TCF7+ memory NK cells 13.3
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 13.3
Transcriptome of iPSC-derived Neural Cells with Heterozygous Knockout in CHD8 13.27
Comparison of expression profiles of APP-depleted prostate cancer cells (LNCaP) 13.26
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 13.19
Rorc disruption in human FG pancreatic cancer cells 13.18
Analysis of HPV16 E2 host gene expression using TERT immortalized keratinocytes (NOKs) cell lines and RNA-sequencing 12.98
Effects of Cardiac Glycosides on RNA Expression in Prostate Cancer LNCaP-abl Cells 12.95
Investigation into human Tra2 protein-dependent splicing in MDA-MB-231 cells using iCLIP and RNA-seq 12.95
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 12.89
Transcriptome analysis of Zika infected neural stem cells 12.85
Zika infected neural stem cells 12.85
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues (sequencing) 12.84
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues 12.84
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG 12.83
Stable oxidative cytosine modifications accumulate in cardiac mesenchymal cells from Type2 diabetes patients: rescue by alpha-ketoglutarate and TET-TDG functional reactivation [human cells RNA-seq] 12.83
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 12.8
Transcription control by the ENL YEATS domain in acute leukemia 12.8
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 12.78
Enriched EWSR1 and EWS-FLI1 RNA-seq of HNRNPH1-silenced TC32 Ewing sarcoma and 293T human embryonic kidney cells. 12.71
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-Seq KO] 12.66
Opposing Effects of Cyclooxygenase-2 (COX-2) on Estrogen Receptor β (ERβ) Response to 5α-reductase Inhibition in Prostate Epithelial Cells 12.61
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 12.61
RNA-seq analysis of BAP1-depleted uveal melanoma cells 12.59
The landscape of alternative splicing in aggressive prostate cancers 12.58
Global transcriptional profiling changes upon knockout of USP22 in human Non-small cell lung cancer cells 12.56
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 12.5
Gene expression profiles of active and restricted R/G-HIV+ primary human fetal astrocytes 12.5
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 12.5
Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage 12.44
SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy 12.43
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 12.38
Transcriptome profiling identified a 3-lncRNA regulatory network in transthyretin against glucose induced hRECs dysfunction 12.35
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging 12.35
Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of binding sites in a cell type-specific manner 12.33
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 12.3
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 12.28
Transcriptomic profiles of human foreskin fibroblast cells in response to orf virus 12.27
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 12.26
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 12.25
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 12.23
Peptidomimetic blockade of MYB in acute myeloid leukemia 12.23
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1, H1 derived APLNR+ cells, CD31+CD34+ cells and CD43+ cells during human early hematopoietic differentiation 12.18
Mitotic stress is an integral part of the oncogene-induced senescence program that promotes multinucleation and cell cycle arrest 12.15
RNA sequencing of HepG2 cells treated with estradiol or estrogen receptor agonist 12.13
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and AXL-/- astrocytes Transcriptomes 12.12
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 12.09
Expression profiling of etoposide-induced senescent cells 12.02
DDX54 regulates transcriptome dynamics during DNA damage response [4SU-seq] 11.98
Conservative alteration of chromosomal expression pattern across human solid tumor types 11.95
Gene expression and 4sUDRB-seq for NF90/NF110 of human scramble and KD HeLa cells. 11.94
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 11.88
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 11.81
lncRNA-PCAT1 knockdown effect on the gene expression of androgen independent LNCaP (LNCaP-AI) cell line 11.8
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 11.79
Integrative Genomic Analysis Reveals Widespread Enhancer Regulation by p53 in Response to DNA Damage 11.79
ChIP-seq of ER and RUNX2 in MCF7 breast cancer cell lines 11.7
TWIST1-induced microRNA-424 drives an intermediate epithelial-to-mesenchymal transition that opposes metastasis 11.69
Gene expression changes in human melanoma cell lines compared to primary melanocytes 11.63
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer [RNA-seq] 11.55
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer 11.55
SIRT6 regulates redox homeostasis in human mesenchymal stem cells by the transactivation of NRF2 11.54
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells 11.52
Culture-induced recurrent epigenetic aberrations in human pluripotent stem cells [RNA-seq] 11.52
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 11.5
Proliferation pause as an early blockade of human cellular reprogramming toward pluripotency [RNA-seq analysis] 11.49
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 11.41
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 11.36
3’READS+, a sensitive and accurate method for 3’ end sequencing of polyadenylated RNA 11.32
The Promyelocytic Leukemia Zinc Finger Dependent Transcriptome during Human Endometrial Stromal Cell Decidualization 11.25
shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 reveals set of genes potentially coregulated by MED25 and ETV4 11.24
Genome-wide occupancy of FLAG-MED25 and ETV4 and expression profiling of shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 11.24
Cranial pericytes derived from neural crest cells reveal an inherent cell type-specific defect in Alzheimer's Disease 11.24
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 11.24
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 11.24
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 11.18
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent 11.18
Cis-Regulatory Circuits Regulating NEK6 Kinase Overexpression in Transformed B Cells Are Super-Enhancer-Independent (RNA-seq) 11.18
IL-33 activates tumor stroma to promote intestinal polyposis 11.15
Coordinated control of senescence by lncRNA UCA1 and a novel CAPERα/TBX3 co-repressor 11.13
TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality 11.11
FBXW7 modulates stress response by post-translational modification of HSF1 11.04
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 11.04
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 11.0
LncRNA expression profiling of ischemic stroke patients 11.0
Statins modulate endothelial transcriptional profile by inhibiting EZH2 10.9
Inducible three-factor direct reprogramming to nephron progenitors using piggyBac transposons 10.85
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 10.82
Characterization of transcriptomics landscape in HUVEC cells exposed to oxidative stress (Total RNA) 10.81
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 10.81
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 10.81
miRNA-1343 attenuates pathways of fibrosis by targeting the TGF-beta receptors [RNA-seq] 10.81
UV_24h_GRO-Seq 10.77
Recruiting Endogenous ADARs with Antisense Oligonucleotides to Reprogram the Transcriptome 10.77
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 10.74
Studying the selectivity of a targeted small molecule degrading a hypoxia-associated non-coding RNA 10.71
Transcriptomic analysis of the HOTAIR-regulated genes 10.7
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis [MultiDisease] 10.68
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 10.67
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 10.67
Determination of tRNA aminoacylation levels by high throughput sequencing 10.62
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 10.6
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 10.6
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 10.59
RNA-Seq of PRMT1 overexpression ECA109 cells 10.58
Neonatal and adult human testis defined at the single-cell level 10.56
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 10.54
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 10.54
Aneuploidy triggers an immune response 10.52
Mammalian Hbs1L deficiency causes Pelota depletion and is associated with a unique phenotype 10.48
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 10.48
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq B-ALL) 10.46
Bioinformatics analysis of transcriptome related to blood stasis syndrome in diabetes mellitus patients 10.46
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 10.43
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 10.42
Integrated analyses of early responses to radiation in glioblastoma identify new alterations in RNA processing and candidate targets to improve treatment outcomes 10.36
HBEC-shp53-PCHD7 10.35
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 10.34
The effect of Abl kinases,or Ponatinib challenging on breast cancer cells' global transcriptome 10.32
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing 10.3
Reducing the structure bias of RNA-Seq reveals a large number of non-annotated non-coding RNA 10.26
Transcriptomic alterations in fibroblasts from Parkinson's disease patients carrying Parkin mutations 10.25
Co-transcriptional loading of RNA export factors shapes the human transcriptome 10.22
RNAseq of HEK293 cells after Chtop knockdown 10.22
MYC dependent mRNA translation shapes gene expression and cell biology 10.21
Reassessment of Exosome Composition 10.2
Toxoplasma gondii infection of human retinal pigment epithelial cells 10.13
RNA-seq of human foreskin fibroblast cells lacking RB, p130, and p107 treated with doxorubicin. 10.1
Global transcriptional profiling changes upon knockdown of LKB1 in human glioblastoma cell lines 10.09
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 10.06
Suppression of NAF-1 in Breast Cancer Cells Reduces their Tumorigenicity by Interfering with Cellular Iron Distribution and Metabolism and Ensuing ROS Formation and Apoptosis 10.05
Profiling of escape kinetics of viruses subjected to RNAi 10.05
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice 10.04
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 10.02
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 10.01
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 9.99
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 9.99
Downregulation of DDX5/DDX17 and REST 9.98
The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting 9.97
The mSWI/SNF ATPase module mediates subcomplex identity and non-catalytic targeting in SCCOHT [RNA-seq] 9.97
FGF2 induces migration of human bone marrow stromal cells by increasing core-fucosylations on N-glycans of integrins 9.95
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 9.94
Metformin induces chromosome reorganization and changes in gene expression in normal human fibroblasts 9.92
Gene expression analysis of immortalized human liver progenitor-like cells in culture 9.92
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 9.9
Poly(A)-specific ribonuclease (PARN) mediates 3' end maturation of the telomerase RNA component 9.87
Ro60-knockout cells 9.86
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 9.82
Reprogramming of human stem cells towards a rejuvenated and transformation-resisting state by recoding a single nucleotide 9.81
Genome-wide maps of m6A circRNAs identify widespread and cell-type-specific methylation patterns that are distinct from mRNAs 9.78
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 9.68
Transcriptomic analysis of differential expressed genes of human tonsillar epithelial cells UT-SCC-60B in response to EV71 infection 9.63
Gene expression changes after depletion of Cyclin F and atypical E2Fs in HeLa cells. 9.6
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 9.53
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with tcons_00001221 shRNA or control shRNA 9.51
Osteogenic programming of adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the Polycomb protein EZH2 9.47
Differential gene expression analysis between proliferating and quiescent human dermal fibroblasts 9.38
Identification of differentially expressed genes between senescence and senescence bypass cells 9.33
Fisetin induces autophagy in pancreatic cancer cells via endoplasmic reticulum stress- and mitochondrial stress-dependent pathways 9.28
Contribution of SRF and Nkx2-5 to androgen-dependent gene expression in prostate cancer 9.27
Genome-scale identification of transcription factors that mediate an inflammatory network during breast cellular transformation 9.09
RNA-seq during MCF10A-ER-Src cell transformation and upon factor knockdowns 9.09
Global loss of epigenetic and transcriptional fidility defines a subclass of cancer with immunotherapy resistance 9.03
Gene expression profiling associated with knockdown of RNF20 in human normal and malignant lung epithelial cell lines 8.96
Differential expression of pancreatic cancer PANC1 cells treated with pilocarpine 8.9
ZNF804A transcriptome networks in differentiating human neurons derived from induced pluripotent stem cells 8.89
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 8.79
Expression changes in melanoma cell lines under BRAFi treatment timepoints [RNA-Seq.CellLine.batch4] 8.76
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 8.73
A novel Menin-MLL inhibitor induces specific chromatin changes and eradicates disease in models of MLL-rearranged leukemia [RNA-Seq II] 8.67
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 8.65
N6-methyladenine DNA Modification in Glioblastoma 8.6
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 8.6
Transcriptome of U251 cells overexpression complement component 7 8.58
The Genetic Landscape of Diamond-Blackfan Anemia 8.58
A rare subpopulation of melanoma cells with low expression of metastasis suppressor NME1 has a neural crest-like phenotype and is highly metastatic in vivo 8.54
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 8.4
Effect of PBK knockdown on C4-2 cell transcriptome 8.39
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 8.38
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 8.22
The MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in MLLr AML 8.18
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 8.18
Genomic location of PRMT6-dependent H3R2 methylation is decisive for the transcriptional outcome of associated genes 8.18
Transcriptome analysis of PRMT6 knock-out in NT2/D1 cells 8.18
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice [RNA-seq] 8.08
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice 8.08
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 8.06
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 8.05
The contribution of Alu exons to the human proteome 8.03
Cell responses to dysregulated VZV-induced cell-cell fusion 8.02
Transcriptome-wide identification of CELF2 functional targets in T cells 8.0
EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC 8.0
Inhibition of TAZ contributes radiation-induced senescence and growth arrest in glioma cells 7.99
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 7.99
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 7.99
Differential Protein Occupancy Profiling of the mRNA Transcriptome 7.94
PolyA-sequencing in Kelly and Kelly E9R neuroblastoma cells treated with THZ531 or DMSO 7.9
RAID allows multiplexed quantification of intracellular (phospho-)proteins and transcriptomes from fixed single cells 7.87
Transcriptome of iPSC-derived Cerebral Organoids with Heterozygous Knockout in CHD8 7.76
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection [RNA-seq] 7.4
Adenovirus Small E1A Employs the Lysine Acetylases p300/CBP and Tumor Suppressor Rb to Repress Select Host Genes and Promote Productive Virus Infection 7.4
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 7.33
Prolyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer 7.26
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 7.15
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 7.08
Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates 7.05
Human cells contain natural double-stranded RNAs with potential regulatory capacity 7.03
mRNA expression in iPS cells generated by a synthetic self-replicative RNA 7.0
Regulation of protein translation during mitosis 6.98
Next Generation Sequencing upon siRNA-mediated knockdown of EIF5A in MCF-7 cells. 6.93
Recapitulating and Deciphering Tumor-stroma Microenvironment by Using a “LEGO” like 3D printed microfluidic device 6.8
Targeting MTHFD2 in Acute Myeloid Leukemia 6.8
RNA-Seq and ChIP-Seq reveals SQSTM1/p62 as a key mediator of JunB suppression of NF-kB-dependent inflammation 6.79
JunB control of keratinocyte-mediated inflammation [RNA-seq] 6.79
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq 2] 6.76
Identification of HOXB13 target genes responsive to BET inhibitors 6.76
mitoCPR - a surveillance pathway that protects mitochondria in response to mitochondrial import stress 6.68
mitoCPR - a surveillance pathway that protects mitochondria in response to mitochondrial import stress [human] 6.68
RNA-seq of RKO cells with cTAZ KO or putback 6.68
Comparative Analysis of Cas9 Activators Across Multiple Species 6.56
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 6.51
Identifying transcripts that are transcriptinoally regulated by CBFB and RUNX1 using RNAseq 6.49
EWS-Fli and LNC regulated genes in comparison to GFP samples 6.46
Capturing the Interactome of Newly Transcribed RNA 6.42
Capturing the Interactome of Newly Transcribed RNA (RICK) 6.42
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 6.4
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 [3mRNA-seq] 6.4
Evolving Spindlin1 Small Molecule Inhibitors Using Protein Microarrays 6.37
The impact of stanniocalcin 1 on the transcriptome of human cord blood stem/progenitors 6.37
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 6.37
m6A-dependent regulation of messenger RNA stability 6.35
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events 6.27
Transcriptional profile in dermal fibroblasts from patients with collagen VI related muscular dystrophy 6.25
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 6.0
O-glcnAc reprograms cellular energetics 5.86
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 5.79
Characterization of Type I Interferon pathway during Hepatic Differentiation of Human Pluripotent Stem Cells and hepatitis C virus infection 5.78
6mer seed toxicity in tumour suppressive microRNAs 5.76
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 5.72
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 5.72
Transcriptome-wide analysis of the role of HTLV-1 Tax PBM in T-Cells from infected humanized-mice (hu-Mice) 5.72
Identification of downstream genes regulated by YAP1 through knockdown and overexpression of YAP1 in U251 cell with a stably expression of mutant APP 5.68
Interaction between mitoNEET and NAF-1 in cancer cells 5.41
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 5.33
Genome-wide analysis of ferroptosis related genes in liver cancer cells. 5.29
RelA mutants 'reconstituted' and cell cycle synchronized HCT116 Colorectal Cancer Cells 5.22
UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation 5.19
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 5.17
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 5.16
Transcriptome Analysis of CircMRPS35 mediated mRNA expression profiles 5.12
Hemogenic Endothelium transcriptome along the timeline of hESC differentiation 5.11
Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq_siRNA] 4.96
Smad5 acts as an intracellular pH messenger and maintains bioenergetic homoeostasis 4.96
Gene expression from AsPC-1 cells treated with PTC596 and DMSO 4.94
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 4.9
polyA RNA Sequencing Analysis of HTR-8/SVneo cells after lnc-SLC4A1-1 overexpression 4.81
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer [RNA-seq] 4.8
Increased Serine and One Carbon Pathway Metabolism by PKCl/i Deficiency Promotes Neuroendocrine Prostate Cancer 4.8
YAP and MRTF-A, transcriptional co-activators of RhoA- mediated gene expression, are critical for glioblastoma tumorigenicity 4.78
METTL3 and WTAP 4.73
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 4.64
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 4.6
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis 4.53
Epigenetic alterations affecting transcription factors and signaling pathways in stromal cells of endometriosis: Expression data (RNA-seq) 4.53
RNA-sequencing of cells derived from the site of inflammation of Juvenile Idiopathic Arthritis patients 4.51
Epigenetic profiling and RNA-sequencing of Juvenile Idiopathic Arthritits (JIA) patients 4.51
Genome wide characterization of a STAT1-independent antiviral and immunoregulatory transcriptional program induced by IFNβ and TNFα reveals non-canonical STAT2 and IRF9 pathways 4.42
Next Generation Sequencing upon siRNA-mediated knockdown of DRAIC in MCF-7 cells. 4.4
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 4.38
Small-molecule targeting of brachyury transcription factor addiction in chordoma 4.34
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction [III] 4.33
EPCR Expression Defines the Most Primitive Subset of Human HSPC and Is Required for Their In Vivo Activity 4.24
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 4.2
Gene expression profile of multiple myeloma cell lines treated with CB-5083 4.05
The transcriptome and chromatin accessbility landscape of mammalian germline 4.04
12hr 5-FU treatment vs. DMSO in SJSA cells (from 'A kinase independent role for CDK19 in p53 response') 4.0
Hyper-activation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2 3.83
Transcriptomic analysis of cultured isogenic myotonic dystrophy type 1 myoblasts with and without the DMPK CTG repeat 3.68
Characterization of the Merkel cell carcinoma miRNome 3.49
Transcriptome of human keratinocytes with or without HPV16 oncogene expression 3.47
Impaired DNA damage metabolism promotes autoimmunity in TREX1 deficiency  3.41
Transcriptome analysis in a radiosensitive and a radioresistant cell line after ionizing radiation 3.36
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5’ and 3’ Ends of Genes 3.35
PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO 3.21
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 3.19
The transcriptome effect of overexpressing EZH2 in MCF7 3.18
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 3.14
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 3.14
RNA-seq after siRNA targeting DDX24 applied to iHUVECs cell lines 3.13
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 3.05
Acetylation-Dependent Control of Global Poly(A) RNA Degradation by CBP/p300 and HDAC1/2 3.04
RNA-seq analysis of control and Myc-induced U2OS cells 3.02
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 3.02
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 2.98
Gene expression profiles in HMC3 cells after exposure to ketamine or its active metabolites: 2R6R-HNK and 2S6S-HNK 2.96
Ribosomal protein RPL26 is the principal target of UFMylation 2.93
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 2.92
Combined MEKi (GDC-0973) and WNT (G007-LK) treatment in APC and KRAS mutant HCT-15 cell line 2.81
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling 2.77
Long-term in vitro expansion of epithelial stem cells enabled by pharmacological inhibition of PAK1-ROCK-Myosin II and TGF-β signaling (RNA-seq) 2.77
Defective transcription elongation in a subset of cancers confers immunotherapy resistance (human cell lines RNA-Seq) 2.76
Transcriptome-wide response to synthetic chromatin protein PcTF 2.73
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 2.59
High-throughput RNAi cell viability screen to identify selective targets for EWS-FLI1 positive Ewing sarcoma 2.52
ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin 2.35
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 2.21
Transcriptional profiling of growing and senescent WT and IL-1R-depleted IMR90 cells 2.13
Dual RNA-seq – High-resolution comparative Dual RNA-seq time-course 2.06
Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains 2.06
Zika virus infection reprograms global transcription of host cells to allow sustained infection 2.05
A novel target of EZH1/2 for treatment of mantle cell lymphoma 1.94
Copper Regulation of HIF-1 Transcription Activity 1.92
Copper Regulation of HIF-1 Transcription Activity [RNA-seq] 1.92
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 1.86
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 1.81
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 1.81
CBFβ-MYH11 fusion blocks hematopoietic differentiation via repression of a GATA2 gene program 1.81
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 1.69
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 1.64
Effect of BCL11B knockdown on transcriptome of human T-cell precursors 1.58
SNHG12 knockdown in Human Umbilical Vein Cells under ROS conditions. 1.55
RNA sequencing analysis of human podocytes reveals glucocorticoid regulated gene networks targeting non-immune pathways 1.54
6mer seed toxicity in viral microRNAs 1.5
RNA-seq from primary skin fibroblasts, derived of matched pairs of middle and late donor age 1.47
Aging signatures developed from a longitudinal study design are dominated by reduced transcription of genes involved in protein synthesis. 1.47
Gene expression profiling by RNA-seq of SW480 TGM2 knockdown cells 1.44
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 1.42
Mouse Dux is myotoxic and shares partial functional homology with its human paralog DUX4 1.32
RNASeq of Arg2 gRNA or scrambled gRNA CRISPR'd Tregs 1.31
Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity 1.31
IFN-γ Represses M2 Gene Expression in Human Macrophages by Suppressing and Disassembling MAF-binding Enhancers [RNA-seq] 1.22
Interferon-γ Represses M2 Gene Expression in Human Macrophages by Disassembling Enhancers Bound by the Transcription Factor MAF 1.22
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 1.16
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 1.16
Joint-specific DNA transcriptome signatures in rheumatoid arthritis [RNA-seq] 1.14
RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment 1.14
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_Stability] 1.09
The impact of oil spill to lung health – insights from an RNA-seq study of human airway epithelial cells 1.02
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 1.01
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 1.01
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 1.0
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 0.97
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 0.93
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 0.83
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 0.81
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 0.8
Effect of from Human Umbilical Vein Endothelial Cells 0.79
Expression profile of MM.1S tumors folloiwing treatment with bortezomib 0.74
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 0.69
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis 0.51
ETS1 induction by the omental microenvironment promotes ovarian cancer metastasis [RNA-Seq] 0.51
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue 0.45
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 0.37
4C-seq of insulin promoter, knockdown of INS promoter activity and Genome-wide maps of chromatin state in EndoC-βH1 Cells 0.35
Viral shRNA Knockdown of INS Promotor Activity in EndoC-βH1 Cells  0.35
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.34
An siRNA screen identifies CHD4 as a target for epigenetic therapy 0.29
Exogenous rescue of KLHL9 in SF210 cell line 0.27
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 0.25
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 0.25
WNT signaling memory is required for ACTIVIN to function as a morphogen 0.13
Modulation of nonsense-mediated decay by rapamycin 0.1
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and SMAD4 Y95 Mutation Transcriptomes 0.04
A cell cycle-based functional screen to identify lncRNA-based cancer biomarkers 0.03
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 0.01
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 0.01
Targets mediated microRNA arm-imbalance promotes gastric cancer progression [lncRNA] 0.0


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