Gene Query: WDR46

Dataset Description Geneva Score
3’READS+, a sensitive and accurate method for 3’ end sequencing of polyadenylated RNA 23.12
Phosphatase inhibitor PPP1R11 modulates resistance of human T cells towards Treg-mediated suppression of TCR signaling 21.46
Genome wide miR-191 target profile determined by RIP and gene expression profiling 19.35
miR-191 regulates human cell proliferation and directly targets multiple oncogenes [seq] 19.35
Global transcriptome analysis of HAP1 cells 18.89
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 18.35
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 18.16
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 17.47
Total RNA-seq in ALL-SIL upon JQ1 inhibition 17.37
Effect of ROQUIN2(Y691F) expression on mRNA levels upon BCR stimulation 17.21
Identification of transcription start sites for human A549 cell line using ReCappable-seq 16.86
TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality 16.13
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression 15.97
EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression [RNA-seq] 15.97
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function [Rnase-Seq] 15.57
Open chromatin mapping identifies transcriptional networks regulating human epididymis epithelial function 15.57
METTL3 promotes translation in human cancer cells 15.39
Differetially expressed genes after hTR overexpression in U2OS cells 15.27
Nuclear Parkin Regulates Transcriptional Response during Hypoxia 14.5
Characterization of human CDK12 and CDK13 in the regulation of RNA processing 13.84
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 13.22
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 13.13
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 12.9
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 12.89
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 12.77
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 12.77
Loss of histone macroH2A1 in hepatocellular carcinoma cells promotes paracrine-mediated chemoresistance and CD4+CD25+ T regulatory cells activation 12.51
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 12.48
Regulating Interleukin-2 activity with engineered receptor signaling clamps 12.44
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 12.06
A common cell state in Triple Negative Breast Cancers represents a druggable vulnerability 11.88
Proteinase-Activated Receptor 4 (PAR4) mediates cell membrane blebbing in a Gaq/11, Gai independent, RhoA and ß-arrestin-dependent manner. 11.78
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 11.58
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 11.53
RNA Sequencing Reveals Immunosuppressive Role of Anthrax Lethal Toxin in Human Lung Epithelial and Monocytic Cells 11.5
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 11.38
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 11.38
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 11.17
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 11.17
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 10.93
Wide-scale analysis of alternative polyadenylation (APA) associated with proliferation and transformation using 3'-Seq 10.85
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies 10.81
Click chemistry enables comprehensive preclinical evaluation of targeted epigenetic therapies [RNA-seq] 10.81
Transcriptomic analysis of T84 colon carcinoma cell line treated with trametinib, JQ1 or their combination 10.74
H3K27ac ChIP-Seq and mRNA-Seq analysis of five human B-lymphoblastoid cell lines (LCLs) prepared from the same healthy male individual (CEPH/UTAH). 10.6
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 10.6
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 10.35
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 10.17
Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen 10.1
The landscape of alternative splicing in aggressive prostate cancers 10.04
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 9.95
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 9.91
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 9.91
Small molecule inhibition of ERK dimerization prevents tumorigenesis by Ras-ERK pathway oncogenes 9.9
Nuclear import of the DSCAM-cytoplasmic domain drives signaling capable of inhibiting synapse formation 9.77
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 9.63
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 9.62
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 9.62
HOXC6 affects the malignant phenotype of esophageal squamous cell carcinoma cells 9.48
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 9.3
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 9.3
The SPOP-containing Complex Functions as an E3 Ligase for SETD2 to Regulate Gene-Specific H3K36me3-Coupled Alternative Splicing 9.23
transcriptomic profiling of HEK293 cells upon individual knockdown of the splicing factors RBM17, U2SURP or CHERP 9.23
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 9.2
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 9.2
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells [RNA-seq] 9.18
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells 9.18
Circular RNAs in the mammalian brain are highly abundant, conserved, and dynamically expressed 9.1
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 9.01
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 8.92
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 8.92
Gene expression profile of human multiple myeloma cell line MM.1S after knockdown of KDM6B 8.81
Transcriptome of activated human and mouse MAIT cells 8.8
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 8.73
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors [RNA-seq] 8.64
Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors 8.64
RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH) 8.64
Epigenetic siRNA and chemical screens identify SETD8 inhibition as a new therapeutic strategy of p53 reactivation in high-risk Neuroblastoma. 8.58
High-throughput RNA sequencing on circular RNA profiles of human pancreatic cancer cell lines and gemcitabine resistant pancreatic cancer cell lines. 8.54
U1 snRNP telescripting regulates size-function stratified human genome 8.52
RNA sequencing of primary human platelets and in vitro cell lines 8.48
Single-nucleotide-resolution mapping of HBV promoters using CAGE 8.45
Endothelial gene expression analysis 8.39
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 8.39
Global transcriptional profiling changes upon knockdown of LKB1 in human glioblastoma cell lines 8.37
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 8.32
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 8.32
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 8.32
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 8.32
The X-linked DDX3X RNA helicase dictates translation re-programming and metastasis in melanoma 8.26
Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing 8.26
Gene expression changes in HSV-1 infected HeLa cells with knockdown of B2M 8.25
DHX15 regulates CMTR1-dependent gene expression and cell proliferation 8.22
MeRIP-seq for heat shock in B-cell lymphoma cells 8.16
IQGAP3 interacts with Rad17 to activate the MRN/ATM/Chk2 signaling and promote radioresistance in lung cancer 8.1
RNA-seq analysis of BAP1-depleted uveal melanoma cells 8.09
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 8.06
A transcriptome-wide divergence in protein translation scales with LIN28B expression 8.05
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity 8.04
RNA-seq analysis of RALD iPSCs after in vitro differentiation 8.04
RNA seq with AML (NB4) cells upon FTO inhibition 7.99
IL-1β induces the rapid secretion of the antimicrobial protein IL-26 from Th17 cells 7.99
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 7.98
SETBP1-WT and SETBP1-G870S epigenetic landscapes 7.98
5hmC and gene expression data in breast cancer cell lines treated with an antioxidant 7.94
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 7.91
Genome wide expression change by RNF168 knocking down in MCF-7 cells 7.74
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 7.62
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 7.62
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 7.61
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 7.61
Human embryonic stem cells in E8 and AKIT culture medium 7.56
Growth factor-free, chemically-defined culture system for expansion and derivation of human pluripotent stem cells 7.56
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 7.48
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 7.47
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 7.47
RNA-seq of resting and activated CD4+ T cells +-JQ1 7.47
MUC1-C represses the RASSF1A tumor suppressor and activated Kras signaling in human carcinoma cells 7.4
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 7.34
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 7.33
Hijacking of stress response machinery by oncogenes in acute leukaemia 7.33
Transcriptional regulation in pluripotent stem cells by Methyl CpG binding protein 2 (MeCP2) 7.28
Whole Transcriptome RNASeq Data for Cell-Sorted Antibody Secreting Cells (ASC) 7.28
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 7.27
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 7.22
Pharmacologic inhibition of STAT5 in AML 7.21
Lysine benzoylation is a novel histone mark [RNA-seq] 7.16
Lysine benzoylation is a novel histone mark 7.16
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 7.14
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 7.14
Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear RNA 7.12
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 7.02
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer 6.97
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage (RNA-seq) 6.95
BRG1 recruitment by transcription factors MITF and SOX10 defines a specific configuration of regulatory elements in the melanocyte lineage 6.95
High-throughput sequencing of pluripotent cells 6.94
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 6.94
Nuclear HNRNPA2B1 HITS-CLIP and RNA-seq 6.91
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia 6.91
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [RNA-seq] 6.91
RNA-seq analysis of melanoma and carcinoma cells expressing FOXQ1 6.89
SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells 6.86
Gene expression changes in human melanoma cell lines compared to primary melanocytes 6.83
AUF-1 affected genes in human skin cells 6.83
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 1: RNA-seq) 6.75
The influence of PPFIA1 silencing to gene expression in breast carcinoma cell line and head and neck squamous cell carcinoma cell lines by RNA-sequencing in three dimensional collagen I 6.71
Mechanosensitive ion channel regulates tissue stiffening to promote glioma aggression 6.65
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 6.63
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer [RNA-Seq] 6.62
Expanding the Nucleoside Recoding Toolkit: Revealing RNA Population Dynamics with 6-thioguanisine 6.62
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 6.62
Gene expression profiling of leukemia cells following asparagine depletion 6.61
Two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 6.58
Gene expression profiling in two dimensional and extracellular matrix based three-dimensional cultures of lung and breast cancer cells 6.58
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 6.56
RNA-Seq Analysis of Anacardic Acid Treated MCF7 and MDA-MB-231 Breast Cancer Cell Lines 6.47
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 6.47
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 6.46
Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells 6.46
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 6.45
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 6.45
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 6.45
Epigenetic silencing of the tumor suppressor RASSF4 favors multiple myeloma progression 6.43
Glioblastoma stem cells infected by ZIKA virus 6.41
Metastasis in triple negative breast cancer is dependent on ΔNp63/CXCL2/CCL22-mediated recruitment of myeloid-derived suppressor cells 6.37
The mRNA export receptor NXF1 coordinates transcriptional dynamics, alternative polyadenylation and mRNA export 6.37
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia 6.36
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 6.36
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes 6.35
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 6.32
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia [RNA-seq] 6.31
ncRNA (non-coding RNA) signature in endothelial cells during hypoxia 6.31
RNA-seq and ChIP-seq analysis of BMI1 or RING1B-silenced prostate cancer cells C4-2 6.3
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 6.27
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells 6.25
Transcriptome analysis of H9 hESC derived cerebral organoids 6.25
Translocation of dense granule effectors across the parasitophorous vacuole membrane in Toxoplasma-infected cells requires the activity of ROP17, a rhoptry protein kinase 6.25
hiPSCs unravel aberrant TGFβ signaling as an etiology of left ventricular non-compaction 6.23
Landscape and variation of RNA secondary structure across the human transcriptome 6.22
Comparative transcriptomic analysis of human and Drosophila extracellular vesicles reveals extensive conservation 6.19
Selective modulation of inflammatory Natural Killer (NK) cell phenotypes following histone H3K27 demethylase inhibition [RNA-Seq] 6.18
Selective modulation of inflammatory Natural Killer (NK) cell phenotypes following histone H3K27 demethylase inhibition 6.18
Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination 6.15
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation (Ribo-seq, RNA-seq) 6.15
hTERT promotes cell adhesion and migration independent of telomerase activity 6.13
Analysis of gene expression, motif and pattern of m6A modified region and m6A enrichment level in Ocular melanoma and Melanocyte cell lines. Gene expressin analysis of METTL3 knock down in PIG1, ALKBH5 knock down and HINT2 over expression in OCM1. 6.12
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 6.07
Expression alterations induced by restoration of AXIN1 expression in SNU449 hepatocellular carcinoma cells 6.07
EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC 6.02
Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network 5.99
Global gene expression profile of dasatinib-resistant RCH-ACV cells 5.97
Cajal bodies are linked to genome conformation 5.94
Cajal bodies are linked to genome conformation [RNA-Seq] 5.94
Proteomics identifies a marker signature of MAPKi resistance in melanoma 5.94
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival 5.93
Spontaneous single-copy loss of TP53 in human embryonic stem cells markedly increases cell proliferation and survival [RNA-Seq] 5.93
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer 5.91
LncRNA NONHSAT113026 represses renal cell carcinoma tumorigenesis through interacting with NF-κB/p50 and SLUG 5.89
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line [RNA-Seq] 5.86
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line 5.86
Transcriptome analysis upon C6orf203 silencing 5.84
RUNX2/CBFB modulates the response to MEK inhibitors through activation of receptor tyrosine kinases in KRAS mutant colorectal cancer 5.8
RNA-sequencing WT vs SOCS3 knockout Glioblastoma stem-cells 5.76
Analysis of transcriptome changes following SOX2 knockdown in three different Ewing sarcoma cell lines 5.75
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 5.74
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 5.74
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 5.74
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 5.73
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 5.69
Single-cell analysis of adult human ovary using 10X genomics 5.68
Transcriptional repression in hypoxia is mediated by the Sin3A histone deacetylase complex [RNA-seq] 5.67
Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML 5.66
Identification of mRNAs with reduced ribosomal loading upon knock-down of translation factor DAP5 from hESCs. 5.64
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 5.63
The effect of REST and its alternatively spliced transcript, REST-003, on breast cancer invasiveness 5.57
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 5.57
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 5.55
Positively selected enhancer elements endow tumor cells with metastatic competence 5.54
Chromatin landscape of human visceral and subcutaneous adipocytes 5.52
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 5.52
SRSF1 role in cellular gene expression and splicing 5.48
RNA-seq of tumor cells following angiopellosis extravasation 5.47
Study functions of ADAR proteins using next generation sequencing of genome and transcriptome 5.46
Analysis of transcriptomes of healthy donor and CD46 deficient CD8 T cells 5.46
Transcriptome analysis of CD8+ T cells from healthy controls and patients wth CD46 deficiency 5.46
MYC dependent mRNA translation shapes gene expression and cell biology 5.42
High RNA polymerase II occupancy on herpes simplex virus 1 late genes early in infection suggests progression to elongation is a critical switch to trigger late viral gene expression 5.4
p53 activity results in DNA replication fork processivity 5.32
Activation of a SOX2-dependent transcriptional regulatory circuit drives glioblastoma. 5.32
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 5.3
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 5.25
PRDM1 inhibits proliferation of human colon cancer organoids 5.24
Genome-wide analysis of ferroptosis related genes in liver cancer cells. 5.21
RG/RGG boxes are common binding motifs in RNA-G-quadruplex-interacting proteins 5.21
RNA-seq analysis of control and ZC3H18-depleted ovarian cancer cells 5.19
Transcriptome sequencing of human coronary artery smooth muscle cell under treatment of nitrated fatty acid 5.18
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 5.1
Transcriptomic analysis of effect of oncolytic measles virus (MV) on transformed and non-transformed bone marrow-derived mesenchymal stem cells (MSCs) 5.1
RNA-seq of HBV-infected Primary Human Hepatocytes treatment by Tazarotene 5.09
ETV7 and interferon response 5.09
Impact of ETV7 activity on interferon-stimulated gene expression in 293T cells treated with interferon alpha 5.09
RNA-seq of HDAC2-disrupted 293FT cells by CRISPR-Cas9 5.08
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 5.08
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (RNA-seq dataset) 5.07
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation. 5.07
Co-Stimulation–Induced AP-1 Activity is Required for Chromatin Opening During T Cell Activation [RNA-seq] 5.07
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 5.03
Over expression of Receptor Activity Modifying Protein 2 in HEK293T cells 5.01
Capturing the Interactome of Newly Transcribed RNA (RICK) 4.99
Capturing the Interactome of Newly Transcribed RNA 4.99
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 4.95
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 4.92
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 4.92
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 4.87
Thymine DNA Glycosylase as a novel target for melanoma: effect of TDG silencing on gene expression in SK-mel-28 melanoma cells 4.86
Isogenic patient-derived human iPSCs, wild-type or heterozygous for PIK3CA-E418K 4.85
Transcriptomic analysis of senescent cells upon PTBP1 knockdown. 4.84
FOXF1 defines the core-regulatory circuitry in gastrointestinal stromal tumor (GIST) 4.81
Expression profile of GIST48 cells with siETV1 or siFOXF1 knockdown 4.81
Sirt6 Oncogene Mediates PI3K/Akt Signaling Activation in Diffuse Large B-Cell Lymphoma 4.77
RNA-sequencing analysis for gene expression profiles affected by CASC9 knockdown 4.73
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 4.71
Patient-derived xenograft platform for metastatic melanoma 4.7
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 4.69
Transcriptional responses of melanoma cells to BRAF inhibition 4.68
Trans-differentiation of human adult peripheral blood T cells into neurons 4.68
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 4.66
Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators 4.64
CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia 4.55
siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia 4.54
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 4.54
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 4.53
Patient Derived Xenograft for Delivery of Precision Medicine in Castrate Resistant Prostate Cancer 4.53
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 4.51
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [MB157_RNA-seq] 4.47
Gene expression changes after depletion of Cyclin F and atypical E2Fs in HeLa cells. 4.44
Club cells surviving influenza A virus infection induce temporary non-specific anti-viral immunity 4.44
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 4.42
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 4.42
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo [RNA-Seq] 4.39
CRISPR Display: A modular method for locus-specific targeting of long noncoding RNAs and synthetic RNA devices in vivo 4.39
Microprocessor mediates transcription termination in long noncoding microRNA genes 4.38
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 4.37
The Wnt/β-catenin and RAS-ERK Pathways were Activated in Tissues of Chemotherapy-Resistant Gastric Cancer PDX Tumor 4.37
RNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946 4.36
Functional interdependency of BRD4 and DOT1L in MLL leukaemia 4.36
DAOY-Notch1/Notch2 knockout: transcriptome comparison 4.36
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 4.34
AhR activity directs BRAF inhibitors resistance in metastastic melanoma 4.29
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 4.29
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 4.29
Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells 4.27
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [GSKJ4_RNA-seq] 4.27
Transcriptome sequencing of K-562 cells 4.23
A map of gene expression in neutrophil-like cell lines 4.22
RNA-Seq of SLNCR1 over-expression in the melanoma cell line A375 4.22
pSILAC mass spectrometry reveals ZFP91 as novel IMiD dependent substrate of the CRL4CRBN ligase 4.21
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 4.2
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 4.13
Long non-coding RNA TYKRIL controls pericyte function and survival in the cardiovascular and central nervous system through regulation of p53 activity and PDGFRß expression 4.11
Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D 4.09
Poly(A)-ClickSeq resolves CF25-mediated alternative poly-adenylation, HeLa 4.05
Genome-wide Gene Expression Profiling in DLBCL Cell Lines Treated with CUDC-907 4.03
The Developmental Heterogeneity of Human Natural Killer Cells Defined by Single-cell Transcriptome 4.03
Primary Human B-cell Temporal Response to CD40L Stimulation 4.03
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 4.01
Discovery and verification of liver cancer marker genes and variable scission based on second-generation sequencing data analysis 3.96
miR941 overexpression experiment 3.94
The anti-leukemic effect of R-2HG depends on its acting as an m6A mRNA modifier-RNA Seq-PBS / R-2HG treatment 3.91
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 3.9
Human cells contain natural double-stranded RNAs with potential regulatory capacity 3.9
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 3.88
Temporal comparison of transcriptomic alterations in human, mouse and rat primary B lymphocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) 3.85
RNA-seq on Enasidenib or DMSO Treated CD71+ Cells from Umbilical Cord Blood (UCB) 3.83
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 3.83
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 3.83
IMP3 regulated gene expression in breast cancer cells 3.79
Tracing Enhancer Networks using Epigenetic Traits (TENET) 3.78
The effect of very-high-molecular-mass hyaluronan (vHMM-HA) on IMR90 transcriptome 3.77
Ribosome profiling upon inhibition of eIF4A 3.74
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 3.69
X-Ray induced DNA-Hydroxymethylation changes 3.67
Global transcriptional changes in the JJN3 myeloma cell line that occur as a result of treatment with 2 pyrrolobenzodiazepine (PBD) monomers 3.64
GLIS3 Transcriptionally Activates WNT Genes to Promote Differentiation of Human Embryonic Stem Cells to Posterior Neural Progenitors 3.58
Transcript abundance in A-T-derived iPSC: Comparing isogenic cells to unrelated individual 3.58
Multi-platform assessment of transcriptional profiling technologies utilizing a precise probe mapping methodology 3.58
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte [RNA-seq] 3.56
Distinct regulatory programs for Sox9 in transcriptional regulation of the developing mammalian chondrocyte 3.56
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability [RNA-seq] 3.54
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability 3.54
Transcriptomic analysis of differential expressed genes of human tonsillar epithelial cells UT-SCC-60B in response to EV71 infection 3.52
Functional role of CPPED1 in trophoblasts. 3.47
NF-κB p65 dimerization and DNA-binding is important for inflammatory gene expression 3.46
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2 [RNA-seq] 3.45
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network 3.45
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 3.44
Polarized B -cell functions 3.43
TT-Seq captures the human transient transcriptome 3.41
RNA sequencing of human mammary epithelial cells 3.34
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 3.34
Transcriptome landscape of HeLa response upon triamcinolone acetonide 3.33
TimeLapse-seq: adding a temporal dimension to RNA sequencing through nucleoside recoding 3.33
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 3.32
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 3.32
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 3.29
Nuclear Actin Regulates Inducible Transcription by Enhancing RNA Polymerase II Clustering 3.24
Real-time observation of light-controlled transcription in living cells 3.22
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq 2] 3.17
ADAR1-editing of cellular and measles virus-derived duplex RNA 3.16
ADAR1-editing in HeLa, p150-KO and ADAR1-KO transcriptomes 3.16
Next Generation Sequencing Facilitates Quantitative Analysis of SW480 cells and HPSE-knockdown SW480 cells Transcriptomes 3.11
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 3.1
Chemotherapeutic drugs inhibiting Topoisomerase 1 activity inhibit TNF-induced inflammatory gene expression 3.09
RNA-seq analysis of human cardiosphere cells with different tubule supportive potential 3.07
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 3.06
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 3.05
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 3.05
Ex-vivo Human Hematopoietic Stem Cell Expansion Requires Coordination of Cellular Reprogramming with Mitochondrial Remodeling and P53 Activation [bulk] 3.04
In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [LN-521 or LN-521+LN-221] 3.04
Searching for target genes of miR-508/509/506/514 in HCT116 cells 3.01
RNA-seq analysis upon ARID1B overexpression 3.0
RNA-Seq analysis of human Tr1, Tregs and IL10neg cells 2.99
TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions 2.95
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 2.94
Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation 2.94
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 2.92
Widespread Transcription beyond mRNA 3’ Ends Yields Abundant Regulatory RNAs 2.87
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 2.82
Myeloid-derived suppressor cells facilitie invasion and metastasis of papillary thyroid cancer cells by repressing miR-486-3p 2.82
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 2.81
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 2.79
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 2.78
A20 regulates canonical wnt-signaling through an interaction with RIPK4 2.77
Circular RNA profiling reveals the different distribution/characteristic and possible transport mechanism among the subcellular fractions 2.73
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 2.68
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HCT116 cells treated with or without TNF-alpha 2.66
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer 2.63
A Suv39H1-low chromatin state drives migratory cell populations in cervical cancer [RNA-Seq] 2.63
Single-Cell RNA Sequencing Reveals Metallothionein Heterogeneity during hESC Differentiation to Definitive Endoderm [RNA-Seq] 2.61
Enhancement of Human B Cell Differentiation and Function in Lymph Nodes by the TLR9 Agonist MGN1703 2.61
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 2.59
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 2.57
Neurofibromin is an Estrogen Receptor alpha Transcriptional Co-repressor in Breast cancer 2.54
Mapping interactions for the TNIP2 hub protein 2.51
Transcriptome of human ILC2s; primary vs IL-1b-primed 2.38
Retroviral Replicating Vectors Deliver Cytosine Deaminase Leading to Targeted 5-FU-Mediated Cytotoxicity in Multiple Human Cancer Types 2.32
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 2.32
CRISPR/Cas9 Screens Reveal Epstein-Barr virus Synthetic Lethal Targets 2.32
Comprehensive molecular phenotypic effects of the large deletion on chromosome 22q11.2 2.31
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 2.3
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 2.3
Effects of Inhibition of CDK8/19 Mediator Kinase by Senexin B in HEK293 cells treated with or without TNF-alpha 2.24
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 2.22
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 2.19
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 2.17
Network-based, cross-cohort discovery of transcriptional mechanisms presiding over maintenance of high-risk neuroblastoma subtype state 2.17
Transcriptomics profiling of Alzheimer’s disease reveal novel molecular targets 2.13
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 2.12
Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 2] 2.12
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis 2.11
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis [RNA-seq] 2.11
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 2.03
HEK293 TFAM Knockout Expression Study 2.0
BBBomics - Human Blood Brain Barrier Transcriptomics Hub 1.99
BBBomics - Human Blood Brain Barrier Transcriptomics Hub [RNA-seq] 1.99
Tunable protein synthesis by transcript isoforms in human cells (Transcript Isoforms in Polysomes sequencing: TrIP-seq) 1.99
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer 1.99
Therapeutic targeting of GCB- and ABC-DLBCLs by rationally designed BCL6 inhibitors 1.98
Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells 1.97
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo 1.97
The hematopoietic master transcription factor PU.1 requires its interaction with the SWI/SNF remodeler to access chromatin de novo [RNA-seq] 1.97
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 1.97
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 1.95
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (human 3' mRNA-seq) 1.9
Changes in CD34 and Erythroid Progenitor Transcriptome After RUNX3 Kock-down 1.84
UPF1/SMG7-dependent MicroRNA-mediated Gene Regulation 1.81
Global transcriptome analysis of WT versus HEB-/- hESCs 1.8
The impact of oil spill to lung health – insights from an RNA-seq study of human airway epithelial cells 1.79
Ambient O2 pressure induces NF-kB1/RelA related inflammatory response in human lung epithelial cells in vitro 1.78
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 1.73
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 1.69
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 1.69
RNA-seq analysis reveals profound changes in transcript profiles between siCon- and siH19-transfected uterine smooth muscle cells (USMC) 1.69
RNAseq of T-ALL upon long non coding rna purturbation 1.63
Hsa-miR-139-5p/HNRNPF axis modulates gene-transcripts balance in thyroid cancer cells 1.62
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 1.54
RNAseq of cell lines with knocked in ESR1 mutations 1.51
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 1.51
Ribosomal protein RPL26 is the principal target of UFMylation 1.49
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 1.4
RNA sequencing of GLO1-depleted MDA-MB-231 breast cancer cells 1.39
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 1.37
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 1.35
The Genetic Landscape of Diamond-Blackfan Anemia 1.33
Epigenetic activation and memory at a TGFB2 enhancer in systemic sclerosis 1.29
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 1.28
Patient-derived xenograft platform for metastatic melanoma: a model for studying resistance to targeted therapy. 1.21
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 1.17
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 1.16
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers 1.14
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers (RNA-Seq) 1.14
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 1.09
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 1.09
miRNAs affected by antagomiR-17 treatment 1.08
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 1.08
Function and hormonal regulation of GATA3 in human first trimester placentation 1.07
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 1.03
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 1.03
Functional genomic analysis of the haploinsufficient tumor suppressor, CUX1 0.99
Functional Significance of U2AF1 S34F Mutation in Lung Adenocarcinomas 0.94
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 0.9
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 0.9
IKZF1 as a Master Regulator of Immune Infiltrate Recruitment in Solid Tumors 0.89
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation 0.89
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation (RNA-Seq) 0.89
Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq] 0.87
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies [RNA-seq data set 2] 0.87
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 0.84
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 0.78
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 0.78
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 0.75
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 0.72
Gene expression changes due to PARP knockdown in human cells 0.7
Transcriptome profiling of A2M treated A549 Cell Line Samples 0.64
Impact on erythroid progenitor type on erythroid differntiation 0.62
YTHDF1 Amplifies Wnt/β-Catenin Signaling to Promote Intestinal Stemness 0.58
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.55
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.55
Evaluating and comparing the Transcriptome of (human) Hek 293 based cells, expressing either CHD3 or CHD4 0.54
Transcriptome profiling of 5 human adenocarcinoma cell lines 0.52
Identification of a unique gene expression signature in mercury and 2,3,7,8-tetrachlorodibenzo-p-dioxin co-exposed cells 0.51
RNA-seq of three Ewing sarcoma cell lines (A673, SK-N-MC, RDES), transfected with either siControl or siMYBL2. 0.48
Cooperation of dominant oncogenes with regulatory variants shapes clinical outcomes in pediatric cancer 0.48
Transcriptome of melanoma cell lines resistant to inhibition of the MAPK pathway. 0.47
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 0.45
A Reproducibility-Based Computational Framework Identifies An Inducible, Enhanced Antiviral Dendritic Cell State In HIV-1 Elite Controllers (TLR perturbation Bulk RNA-Seq) 0.45
KSDM1b Role in Ewing Sarcoma 0.45
siRNA-mediated knockdown 0.44
Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome 0.43
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 0.41
Hypoxic regulation of gene expression in HUVEC is dominated by EPAS1 0.38
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 0.35
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 0.32
Heterogeneous maintenance of human tissue resident memory T cells based on efflux capacities 0.32
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.31
single cell RNA-seq from GM12878 (ENCSR673UIY) 0.31
PT2385 HIF2A inhibitor treatment of patient derived orthotopic xenograft neuroblastoma cells in the presence or absence of hypoxia 0.31
Genome-wide analysis of the Integrator complex 0.25
Genome-wide analysis of the Integrator complex (HTS) 0.25
RNA-Seq gene profiling comparison from human cDC subsets and pre-cDC subsets 0.24
Radiation enhances melanoma response to immunotherapeutic and synergizes with benzodiazepines to promote improved anti-tumor activity 0.2
PolyA-sequencing in IMR-32 neuroblastoma cells with shRNA mediated depletion of CDK12, CDK13 or GFP. 0.18
Determining mRNA half-lives on a transcriptome-wide scale 0.18
Myc activation coordinates gene transcription and protein translation responses 0.18
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.15
Genome-wide hsa-miR-503, hsa-miR-103, and hsa-miR-494 target profiles 0.05
hsa-miR-503, hsa-miR-103, and hsa-miR-494 genome wide target profiles [RNA-Seq and RIP-Seq] 0.05
Human bone marrow resident natural killer cells have a unique transcriptional profile and resemble resident memory CD8+ T cells 0.04
Characterisation of the EZH2 regulated transcriptome in de novo transformed cells (RNA-Seq) 0.03
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.0


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