Gene Query: WDR5

Dataset Description Geneva Score
Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes 71.68
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 57.41
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 36.08
Gene-Centric Functional Dissection of Human Genetic Variation Uncovers Regulators of Hematopoiesis 26.54
Whole-transcriptome profilings between a pair of HCA7-derived KRAS-wildtype cetuximab sensitive and resistant colon cancer cells from 3D culture 26.5
Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation 22.8
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques [HCC1599_RNA-seq] 19.85
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia [RNA-seq] 19.75
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia 19.75
The landscape of alternative splicing in aggressive prostate cancers 18.76
Alternative splicing of differentiated myeloid cell transcripts after infection by Anaplasma phagocytophilum impacts a selective group of cellular programs 17.97
The LIN28B/let-7 axis is a novel therapeutic pathway in Multiple Myeloma 17.09
Combined cistrome and transcriptome analysis of SKI in AML cells identifies SKI as a co-repressor for RUNX1 16.59
Transcriptome analysis of SKI knock-out in HL60 cells 16.59
EWSR1 influences alternative splicing through direct and indirect mechanisms 16.35
G-quadruplex structures mark human regulatory chromatin 15.74
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis 14.77
KMT2D regulates p63 target enhancers to coordinate epithelial homeostasis [RNA-Seq] 14.77
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 14.46
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 14.42
Comparison between THP-1 cells obtained from either ATCC or DSMZ biorepository 14.32
Dynamic incorporation of histone H3 variants into chromatin is essential for acquisition of aggressive traits and metastatic colonization 14.28
DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation 14.02
RNA-seq of YB5 cells treated with Proscillaridin A 13.94
Adipocyte-derived lipids mediate melanoma progression via FATP proteins 13.68
Assessing the effect of SUPT4H1 RNAi on the transcription of a repeat-containing reporter construct 13.67
TNF response in promyelocytic and granulocytic forms of HL60/S4 cells 13.61
Divergent effects of eRF3 and Upf1 on the expression of uORF carrying mRNAs and ribosome protein genes 13.41
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation 13.24
To investigate the decay constants (half-lives) of transcript isoforms generated by alternative polyadenylation in proliferating and quiescent cells 13.24
β-catenin/Tcf7l2 dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer 12.81
Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with Eralpha 12.61
FOXD3 is a novel tumor suppressor in lung cancer 12.46
KLF6-dependent transcription in renal cancer cells 12.4
ChIP-seq and RNA-seq in BGC823 cells after downregulation of GAS1 expression 12.16
A novel lncRNA GAS1 promotes gastric carcinogenesis and acts as a modular scaffold of WDR5 and KAT2A complexes to specify the histone modification pattern [RNA-seq] 12.16
A novel lncRNA lncRNA-AK096729 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 12.12
Transcriptome analysis in Neobractatin treated cells 11.84
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 11.76
Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain 11.6
Combined use of astragalus polysaccharide and berberine attenuates insulin resistance in IR-HepG2 cells via regulation of the gluconeogenesis signaling pathway 11.53
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification [Mouse and Human RNA-seq and BS-seq] 11.32
Comparative principles of DNA methylation reprogramming during human and mouse in vitro primordial germ cell specification 11.32
RNA-seq transcriptonal profiling in human primary adult erythroid progenitor cells (ProEs) after shRNA-mediated depletion of TFAM and PHB2 expression 10.83
Nucleosome dynamics in human colorectal cancer specimens reveal activation of a CNOT3-regulated pathway of embryonic stem cell self-renewal 10.59
Identification of diverse target RNAs that are functionally regulated by human Pumilio proteins 10.56
Targeting MYC dependency in ovarian cancer through inhibition of CDK7 and CDK12/13 10.51
RNA-sequencing of human mammary epithelial cells (HMLEs) transduced in vitro with a shRNA against SOX4 or a scrambled shRNA in untreated and TGF-β-treated (16 hours) conditions 10.41
RNA-seq analysis of uveal melanoma cells treated with FR900359 10.34
RNA-seq analysis of FET cells treated with RSPO1 or TGFβ1 10.27
Wnt addiction of genetically defined cancers reversed by PORCN inhibition 10.26
Energy Metabolism during Anchorage-Independence 10.21
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 10.06
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 10.05
A damaged genome's transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks 10.04
Transriptional profiling upon heat shock and recovery in cells deficient for FBXW7 and their wild type counterpart. 9.92
FBXW7 modulates stress response by post-translational modification of HSF1 9.92
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells 9.91
Biological effect of chronic mistranslation in mammalian cells 9.84
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 [RNA-seq] 9.8
ARID2 promotes clear cell renal cell carcinoma in the absence of functional PBRM1 9.8
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3] 9.56
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 9.54
Effect of FGF13 depletion on the H460 cell line 9.45
Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas 9.42
RNA sequencing of BT142 and TS603 cell lines 9.42
miR-191 regulates human cell proliferation and directly targets multiple oncogenes [seq] 9.42
Genome wide miR-191 target profile determined by RIP and gene expression profiling 9.42
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 9.4
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 9.4
DGCR8 acts as a novel adaptor for the exosome complex to degrade double-stranded structured RNAs 9.4
Splicing towards noncoding isoforms in colorectal carcinoma is associated with tumor hypoxia and the DNA damage response 9.3
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 9.19
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 9.1
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 8.97
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma (RNA-Seq) 8.93
The role of PHF19 in promoting H3K27me3 deposition in multiple myeloma 8.93
Global Bidirectional Transcription of the Epstein-Barr Virus Genome During Reactivation 8.87
Hypertonic saline attenuates the cytokine-induced pro-inflammatory signature in primary human lung epithelia 8.82
Widespread N6-methyladenosine-dependent RNA Structural Switches Regulate RNA-Protein Interactions 8.81
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 8.76
Genome wide mapping of polyadenylation sites in proliferating and contact-inhibited cells and cells with knockdown of cleavage and polyadenylation factors 8.74
Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids 8.63
Hierarchy of mono- and bi-allelic TP53 alterations in Multiple Myeloma cell fitness 8.57
Safeguarding nucleolar homeostasis by CBX4 alleviates senescence and osteoarthritis 8.56
Base-resolution mapping reveals distinct classes of N1-methyladenosine methylome in nuclear- and mitochondrial-encoded transcripts 8.49
PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7 8.39
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction 8.39
RUNX1-ETO and RUNX1-EVI-1 differentially program the chromatin landscape in t(3;21) and t(8;21) AML but share global C/EBP-alpha dysfunction (RNA-Seq) 8.39
Next Generation Sequencing Facilitates Quantitative Analysis of HIV-1 Latency in Central Memory T Cells 8.38
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer 8.37
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 8.33
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 8.33
Genes significantly down or Up-regulated upon RNF219 knockdown. [RNA-Seq] 8.08
Supraphysiological Androgens Repress Prostate Cancer Growth and Induce DNA Damage Augmented by PARP Inhibition 8.07
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 8.01
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer (BRD4_JQ1_RNA-seq) 7.99
Regulating Interleukin-2 activity with engineered receptor signaling clamps 7.93
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 7.92
hnRNP C is a key regulator of protein synthesis in mitosis 7.9
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex (RNA-Seq I) 7.87
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator [RNA-seq] 7.84
Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator 7.84
Retinoic Acid Induced Transcriptional Repressor HIC1 is Required for Suppressive Function of Human Induced Regulatory T cells [RNA-Seq 1] 7.81
TALENs-mediated gene disruption of FLT3 in leukemia cells: Using genome-editing approach for exploring the molecular basis of gene abnormality 7.79
Dtx3L and Androgen Signaling in Prostate Cancer 7.79
RNA-seq in SUNE-1 cells after downregulation of DANCR expression 7.78
H3B-8800, a novel oral splicing modulator, induces lethality in spliceosome mutant cancers [Nalm-6] 7.77
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 7.73
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 7.73
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 7.72
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 7.72
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [BAA] 7.69
Conservative alteration of chromosomal expression pattern across human solid tumor types 7.64
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 7.64
UMI-count modeling and differential expression analysis for single-cell RNA sequencing 7.62
Inhibition of TNBC metastasis by Gpx1 7.62
LINE-1 elements are derepressed in senescent cells and elicit a chronic Type-I Interferon response 7.58
Gene expression profiling of leukemia cells following asparagine depletion 7.56
shRNA knockdown of YAP1 in HCC364 cells, various drug conditions 7.52
DDX54 regulates transcriptome dynamics during DNA damage response [RNA-seq2] 7.51
Polysome-associated mRNA profiling of cancer cells in response to CXCL12 and IGF1 7.5
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface 7.49
Differentially expressed vascular development genes for iPSC-ECs from CDI 7.46
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor 7.41
RNA seq data of Hep3B-control, Hep3B-sertraline, Hep3B-XL413, Hep3B-XL413-sertraline, Huh7-control, Huh7-sertraline, Huh7-XL413, Huh7-XL413-sertraline cells 7.41
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 7.33
PR isoform-specific ER and PR chromatin binding and gene expression observed in-vitro in breast cancer cells. 7.31
Atheroprotective flow alters EZH2/H3K27me3 dependent transcriptional profile in human endothelial cells 7.22
AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition 7.21
Coordination of neuron production in mouse and human cerebral cortex by the homolog of Drosophila Mastermind protein 7.2
Selectively targeting bromodomain and extraterminal proteins for degradation as a novel anti-glioblastoma strategy [RNA-seq] 7.18
RNAseq of PRMT4KD in human cord blood derived CD34+ cells 7.12
RNA-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 7.11
RNA-Seq and ATAC-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 7.11
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 7.1
Glioblastoma stem cells infected by ZIKA virus 7.07
circ-ZNF609 regulates G1-S progression in Rhabdomyosarcoma 7.06
Genomic basis for clinical response to histone deacetylase inhibition in advanced urothelial carcinoma 7.02
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 7.01
Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly-dividing de-differentiated state 7.0
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 7.0
A map of gene expression in neutrophil-like cell lines 6.97
A non-catalytic function of carbonic anhydrase IX contributes to the glycolytic phenotype and pH regulation in human breast cancer cells 6.93
RNA-seq analysis of control and NRDE2-depleted breast cancer cells 6.92
Simultaneous quantification of antibody-RNA conjugates and the transcriptome from fixed cells by RAID 6.91
RNA-Seq Samples of siTFE3 in 8988T PDA Cell Line to Investigate Transcriptional Control of the Autophagy-Lysosome System 6.86
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 6.85
Neurotrophic Tyrosine Kinase Receptor 1 is Epigenetically Regulated by IL-13 and Contributes to Allergic Inflammation 6.82
Neonatal and adult human testis defined at the single-cell level 6.79
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines [RNA-Seq] 6.78
Discovery of naturally occurring ESR1 mutations during acquisition of resistance to endocrine therapy in widely used estrogen receptor positive breast cancer cell lines 6.78
STVI-120 Induction of differentiation in human epidermal stem cells followed by differential splicing analysis 6.77
NET-CAGE Characterizes the Dynamics and Topology of Human Transcribed Cis-regulatory Elements 6.73
Transcriptomic Reprogramming of Prostate Cancer Cells Driven by Stroma-Derived SPINK1 6.72
Mechanistic Model-Guided Study of Embryonic Morphogenesis 6.68
Transcriptomes analysis for the regulation of Z36 induced autophagy in HeLa cell death 6.66
Expression analysis of Mebendazole treated THP-1 cells in three paired samples 6.64
Effect of ER stress on MUC1 kidney disease patient derived cells and and treatment by BRD4780 6.64
Cleavage Factor Im as a key regulator of 3’ UTR length 6.64
Transcriptome analysis of A549 cells expressing a SUMOylation-deficient TRIM28 mutant in the context of influenza A virus infection 6.61
Identifying lincRNA as prognostic biomarker for clear cell renal cell carcinoma 6.6
Global transcriptional profiling changes upon knockout of USP22 in human Non-small cell lung cancer cells 6.58
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance 6.57
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq) 6.57
Transcriptional profile of human STAT1-/- fibroblasts expressing IFI6 or empty control vector 6.57
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice [RNA-seq] 6.54
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice 6.54
Genome-wide analysis of STAT3 in diffuse large B-cell lymphoma 6.53
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 6.53
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 6.53
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 6.51
Global analysis of alternative splicing regulated by RBM10 6.5
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 6.44
Hijacking of stress response machinery by oncogenes in acute leukaemia 6.44
Global Transcriptome Analyses of Mammalian Terminal Erythroid Differentiation 6.44
High-throughput sequencing of pluripotent cells 6.44
Distinct gene expression profile of Huh7 cell lines stably overexpressing CRABP1 or 2 6.43
Genome-wide Gene Expression Profiling in DLBCL Cell Lines Treated with CUDC-907 6.43
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines LOUCY and PEER 6.41
Paxillin regulates genomic networks in prostate cancer [LNCaP] 6.41
Gene target specificity of the Super Elongation Complex (SEC) family: How HIV-1 Tat employs selected SEC members to activate viral transcription 6.4
Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases 6.4
EIF1AX-A113 splice and RAS mutations cooperate to drive thyroid tumorigenesis through ATF4 and c-MYC 6.39
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq] 6.38
Differential gene expression of human melanoma cells [RNA-seq] 6.37
GDF6-induced BMP signaling reawakens a neural crest identity in melanoma to prevent cell death and differentiation 6.37
REPROGRAMMING IDENTIFIES FUNCTIONALLY DISTINCT STAGES OF CLONAL EVOLUTION IN MYELODYSPLASTIC SYNDROMES 6.35
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation 6.35
Benzotriazoles reactivate latent HIV-1 through inactivation of STAT5 SUMOylation (RNA-Seq) 6.35
RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells. 6.34
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 6.34
Involvement of Condensin in Cellular Senescence through Gene Regulation and Compartmental Reorganization 6.28
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 6.27
Enhancing human kidney organoid differentiation from pluripotent stem cells with high-throughput automation 6.25
RNA-seq analysis of differentiating human erythroblasts 6.25
Complementary Post Transcriptional Regulatory Information is Detected by PUNCH-P and Ribosome Profiling 6.24
N6-methyladenosine Recruits HNRNPG for Alternative Splicing Regulation 6.24
Novel mutations segregating with Complete Androgen Insensitivity Syndrome and their molecular characteristics. 6.22
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition [RNA-Seq] 6.21
Cooptation of tandem DNA repeats for the control of epithelial-to-mesenchymal transition. 6.21
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 6.15
Selective expression of long non-coding RNAs in a breast cancer cell progression model 6.14
RNA sequencing of primary human platelets and in vitro cell lines 6.13
Induction of Prolonged Early G1 Arrest by CDK4/CDK6 Inhibition Reprograms Lymphoma Cells for Durable PI3Kδ Inhibition Through PIK3IP1 6.12
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 6.12
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-Seq] 6.11
Genome-wide CRISPR-Cas9 screen identifies functionally relevant microRNAs in AML 6.08
Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines 6.08
MOF acetyl transferase regulates transcription and respiration in mitochondria 6.03
Transcriptomic analysis of senescent cells upon PTBP1 knockdown and EXOC7 knockdown 6.03
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma 6.01
RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients 6.0
The interplay between SOX4 and SMAD3 in the context of breast cancer 5.99
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 5.99
PHF20 readers link methylation of histone H3K4 and p53 with H4K16 acetylation 5.98
Mining the stiffness-sensitive transcriptome in human vascular smooth muscle cells identifies long non-coding RNA stiffness regulators 5.97
Identification of Sin3B regulated genes during quiescence 5.96
Translocation of dense granule effectors across the parasitophorous vacuole membrane in Toxoplasma-infected cells requires the activity of ROP17, a rhoptry protein kinase 5.95
RNAseq analysis of ESRP regulated splicing events in prostate cancer 5.94
Total RNA deep sequencing (ribosomal depleted) of human umbilical vein endothelial cells exposed to hypoxia (0.2%) for 12h and 24h or kept under normoxic conditions. 5.93
Endothelial gene expression analysis 5.93
RNA-Seq analysis RPE1 cells following exposure to Nutlin-3 to identify target genes of p53 [tpo12] 5.92
miR941 overexpression experiment 5.91
RNA-Seq to assess the transcriptional effects of G quadruplex stabilization by the G4 ligand PhenDC3 in HT-1080 cells 5.87
Transcriptome Sequencing of Adipose-Derived Mesechymal Stromal Cells 5.86
Mesenchymal stem/stromal cell engulfment reveals metastatic advantage in breast cancer 5.85
Identification of HOXB13 target genes responsive to BET inhibitors 5.85
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of LMNA KD) 5.85
Quiescent glioblastoma cells shift to an epithelial-mesenchymal transition-like gene program 5.83
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 5.79
The Human Testis Cell Atlas via Single-cell RNA-seq 5.75
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 5.7
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 5.67
RNA-seq analysis of RALD iPSCs after in vitro differentiation 5.67
Transcriptomic profiling of O-GlcNAcylated mRNA-protein complexes by using OG-CLAP in HeLa cells. 5.66
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc 5.64
A novel lncRNA lncRNA-AF339830 promotes colorectal carcinogenesis and glucose metabolism by stabilizing and specifying the transcription modification pattern of c-Myc [RNA-Seq] 5.64
Transcriptional landscape changes during human embryonic stem cell derivation 5.59
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 5.56
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 5.56
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 5.55
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer 5.54
Grainyhead-like 2 is essential for androgen receptor expression and activity in prostate cancer (RNA-seq) 5.54
Identifying the molecular mode of action of itraconazole in colorectal cancer 5.54
Biosynthesis of histone messenger RNA employs a specific 3' end endonuclease 5.52
RNA-Seq analysis of cSCC cells after siRNA-induced gene knockdown of lncRNA PRECSIT 5.52
RNA splicing alteration on glioblastoma and normal neural stem cells 5.5
Transcriptomic profiling discloses molecular and cellular events related to neuronal differentiation in SH-SY5Y cells 5.48
FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA 5.46
Gene expression profile in FTSEC cells (FT190 and FT194 cell lines) transduced with shRNA to knockdown RNF20 or with control shRNA using RNA-seq. 5.46
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 5.44
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 5.43
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 5.41
Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2 5.41
RNA-seq analysis to identify the genes regulated by p53-SET interplay 5.4
Transcriptome-wide study of the response of human trabecular meshwork cells to the substrate stiffness increase 5.38
Characterisation of HIF-dependent alternative isoforms in pancreatic cancer 5.38
The SUMO Pathway as a Therapeutic Option in Pancreatic Cancer 5.36
LEDGF and HDGF2, histone H3K36 methyl-binding proteins that assist RNA polymerase II transcription through nucleosomes 5.36
Gene expressions of H9s in different culture systems 5.35
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer 5.35
An evolutionarily conserved function of polycomb silences the MHC class I antigen presentation pathway and enables immune evasion in cancer [RNA-Seq] 5.35
RNA transcriptome sequencing analysis of SGC-7901 cells transfected with tcons_00001221 shRNA or control shRNA 5.34
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma 5.33
Cellular acidosis triggers MondoA transcriptional activity by driving mitochondrial ATP production 5.33
Functional role of CPPED1 in trophoblasts. 5.21
Targeting HuH7 cells with JumonjiC Lysine Demethylase Inhibitors (RNA-Seq) 5.2
RNA-seq of RKO cells with cTAZ KO or putback 5.19
METTL3 and WTAP 5.18
Tumor hypoxia causes DNA hypermethylation by reducing TET activity 5.18
Tumor hypoxia causes DNA hypermethylation by reducing TET activity (RNA-Seq) 5.18
RNA transcriptome analysis during HSV-1 infection 5.17
H3K27ac ChIP-Seq and mRNA-Seq analysis of five human B-lymphoblastoid cell lines (LCLs) prepared from the same healthy male individual (CEPH/UTAH). 5.16
Tracing Enhancer Networks using Epigenetic Traits (TENET) 5.16
An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell 5.14
Epigenetic Lanscape and BRD4 Transcriptional Dependency of PAX3-FOXO1 Driven Rhabdomyosarcoma 5.13
PAX3-FOXO1 requires BRD4 to drive oncogene addiction in RMS cells [RNA-seq] 5.13
Gene expression analysis of human CD8+ T cells treated with a DOT1L inhibitor 5.12
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution [III] 5.12
Deciphering the ‘m6A code’ via quantitative profiling of m6A at single-nucleotide resolution 5.12
AMPK signaling for naïve pluripotency 5.1
AMPK signaling for naïve pluripotency [Hs] 5.1
A comparison of gene expression between lesional and non-lesional derived keratinocytes of Hailey-Hailey disease patients. 5.08
Lyophilized human cells stored at room temperature preserve multiple RNA species at excellent quality for RNA sequencing 5.08
Genomic profiling of human spermatogonial stem cells [BulkRNA-Seq] 5.07
Expression profiles of restoration of BAP1 in a BAP1 deficient cell line 5.06
Transcriptome analysis of BAP1 knockout and restoration 5.06
Exploiting Prmt5-orchestrated intron detention signatures to treat splicing-addicted malignant glioma tumors 5.06
A Surveillance System of Active Enhancers by a RACK7-histone Demethylase Complex 5.02
Uridylation-mediated RNA quality control pathway in mammalian cytoplasm [RNA-Seq] 5.02
TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. 5.02
Differential gene expression by suppression of either SOX2 or TP63 in KYSE70 human esophageal squamous carcinoma cell line. 4.94
Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells 4.93
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction 4.92
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 4.91
RNAseq of ribosomal fractionation to assess the effect of CBFB on translation regulation 4.91
mRNA gene expression profiling in a human AML cell line treated with small molecule inhibitors that impact different RNA polymerase transcription complexes, or their combination, in comparison to a global DNA-damaging anthracycline compound 4.89
Peptidomimetic blockade of MYB in acute myeloid leukemia 4.84
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 4.84
mRNA-seq from Nutlin-3a, doxorubicin, and DMSO treated HCT116 p21-/- cells 4.84
Nm-seq finds thousands of modified 2’-O-methylation sites in mRNA with base precision 4.78
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 2] 4.77
Cajal bodies are linked to genome conformation 4.74
Cajal bodies are linked to genome conformation [RNA-Seq] 4.74
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 4.72
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 4.72
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 4.7
A quantitative chemotherapy genetic interaction map identifies new factors associated with PARP inhibitor resistance 4.7
RNAseq Study in CC-671 Treated Cal-51 Cells 4.65
Innate-like activation of mucosal-associated invariant T cells in mycobacterial infection 4.65
Trans-chromosomal regulation by a novel lincRNA required for adipogenesis that escapes X-chromosome inactivation 4.64
Downregulation of DDX5/DDX17 and REST 4.6
SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF 4.59
The Wnt/β-catenin and RAS-ERK Pathways were Activated in Tissues of Chemotherapy-Resistant Gastric Cancer PDX Tumor 4.56
Neurofibromin is an Estrogen Receptor alpha Transcriptional Co-repressor in Breast cancer 4.53
Poly(A)-ClickSeq resolves CF25-mediated alternative poly-adenylation, HeLa 4.52
Genome-wide modelling of transcription kinetics reveals patterns of RNA processing delays 4.52
Pluripotent stem cell model of Nakajo-Nishimura syndrome untangles proinflammatory pathways mediated by oxidative stress 4.5
Alarmin S100A11 initiates a chemokine response to the human pathogen Toxoplasma gondii 4.49
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 4.42
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 4.42
BASP1 modifies the Tamoxifen response 4.41
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of AIM2. 4.41
Regulation of stem cell property and drug resistance of cancer cells by targeting transcriptional machinery via inhibition of neddylation 4.35
Landscape of Hematopoiesis Described in Induced Pluripotent Stem Cells and Human Bone Marrow 4.35
RNA-sequencing of the GSI treatment of the CUTLL1 cell line 4.31
The impact of pro-inflammatory cytokines on the β-cell regulatory landscape provides insights into the genetics of type 1 diabetes 4.28
Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells 4.22
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 4.21
RNA isoform screens reveal the essentiality and tumor suppressor activity of ultraconserved poison exons 4.2
SMYD2 specificly regulate BIX-01294 induced TP53 target genes revealed by RNA-Seq 4.2
CHD7 is Suppressed in the Perinecrotic/Ischemic Microenvironment and is a Novel Regulator of Angiogenesis 4.18
Tyrosine-1 of RNAPII CTD controls global termination of gene transcription in mammals 4.15
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 4.11
RNA-seq of synchronized S phase or G2 phase cells treated with an ATR inhibitor 4.11
Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid. 4.11
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells 4.1
Comparative whole-transcriptomic analysis between normal and AKAP-Lbc-depleted human embryonic stem cells 4.1
Cell cycle positioning drives heterogeneity within the pluripotent stem cell compartment 4.09
DAOY-Notch1/Notch2 knockout: transcriptome comparison 4.08
Neuronal Development And The Onset Of Electrical Activity In The Human Enteric Nervous System 4.08
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. [RNA-Seq] 4.07
The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. 4.07
BRD9 defines a novel SWI/SNF sub-complex and constitutes a specific vulnerability in malignant rhabdoid tumors [RNA-seq 2] 4.06
Direct identification of endogenous SMG6 targets and a preferred motif spanning SMG6 cleavage sites by parallel analysis of RNA ends in human cells 4.01
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 4.01
Genome-wide Dose-dependent Inhibition of Histone Deacetylases Reveals Their Roles in Enhancer Remodeling and Suppression of Oncogenic Super-enhancers 3.99
RNA-seq of cells with TET1 knockout 3.96
Nuclear Actin Regulates Inducible Transcription by Enhancing RNA Polymerase II Clustering 3.92
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 3.91
MiR-CLIP capture of a miRNA targetome uncovers a lincRNA H19-miR-106a interaction [III] 3.86
Perlman syndrome nuclease DIS3L2 controls cytoplasmic non-coding RNAs and provides surveillance pathway for maturing snRNAs 3.86
Differential Protein Occupancy Profiling of the mRNA Transcriptome 3.85
CREB5 promotes resistance to androgen-receptor antagonists and androgen deprivation in prostate cancer 3.84
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 3.84
MCF-7 as a model for functional analysis of breast cancer risk variants 3.8
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells 3.78
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 3.76
Comparative Analysis of Cas9 Activators Across Multiple Species 3.72
Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP 3.69
Flura-seq identifies organ-specific adaptations in metastasis-initiating cells 3.58
6mer seed toxicity in viral microRNAs 3.56
The cytokine environment influence on human skin-derived T cells 3.52
RNA-seq profile of expanded human ST2-transduced Tregs cultured with IL-2 and TCR in the presence or absence of IL-33 3.51
TAF1 is critical for AE driven leukemogenesis 3.5
TAF1 is critical for AE driven leukemogenesis [RNA-seq] 3.5
Next Generation Sequencing (RNA-Sequencing) for the analysis of RUNX3 targets in H460, H460-ERT2-RUNX3 WT and H460-ERT2-RUNX3 MT(K94/171R mutation) 3.41
6mer seed toxicity in tumour suppressive microRNAs 3.31
Mutant KRAS/BRAF Reprograms the Enhancer Landscape via GATA1 to Drive Chemoresistance 3.3
TT-Seq captures the human transient transcriptome 3.27
The transcriptomic differences between Th1, Tr1, and Tneg cells in controlled human malaria infection 3.26
KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression 3.21
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 3.18
Acquired resistance to MEK-CDK4/6 inhibitor combinations in cutaneous melanoma 3.17
JUNB is a critical AP1 component for SMAD2/3 binding after TGFβ stimulation [RNA-seq] 3.15
SMAD2/3 are redirected to novel sites in MCF10A MII after prolonged TGFβ stimulation 3.15
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 3.13
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 3.1
RNA-Guided Human Gene Activation by Cas9/CRISPR-Based Engineered Transcription Factors 3.08
RNA-seq of MDA-MB-231 cells with TET1 knockout 3.07
RBM25 is a global splicing factor promoting inclusion of alternatively spliced exons 3.07
Global host gene expression changes in KSHV+ PEL cells upon KSHV reactivation 3.03
MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells 3.01
Muscleblind-like 1 suppresses breast cancer metastatic colonization and stabilizes metastasis suppressor transcripts 3.01
MARCKS and lnc-MARCKS act as inflammation regulators 2.99
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 2.94
RNA seq comparison between scrambled and shGRP78 cells 2.93
Gene expression profile of HGC27 gastric cancer cell p53 KO and KD 2.92
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription 2.8
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 2.79
Analysis of gene expression in SKOV3 ovarian cancer cells after knockdown of the long non-coding RNA DNM3OS 2.69
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 2.63
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 2.63
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing [whole transcriptome RNA-seq] 2.6
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation 2.59
Generation of low passage high grade serous ovarian cancer cell lines from primary tumors 2.54
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [Toxin] 2.53
RNA sequencing analysis of triple cytokine-captured human CD4 T cells 2.51
RNA-seq of HEK293T cells overexpressing TET1-FL or TET1-ALT 2.47
Tracing transcriptome profiles of human oocyte cultured by growth hormone or not in vitro by single cell RNA-seq 2.38
The metabolome regulates the epigenetic landscape during naïve to primed human embryonic stem cell transition 2.35
Analysis of an artificial zinc finger epigenetic modulator: widespread binding but limited regulation 2.3
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 2.26
RNA-Seq analysis of human Tr1, Tregs and IL10neg cells 2.23
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary (I) 2.22
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 2.19
Systematic analysis of gene expression profiles controlled by hnRNP Q and hnRNP R, two closely related human heterogeneous nuclear ribonucleoproteins. 2.14
Determining mRNA half-lives on a transcriptome-wide scale 2.13
Effects of transcription factor CEBPA knockdown on vitamin D target gene regulation in THP-1 cells 2.05
The pioneer factor CEBPA modulates vitamin D signaling 2.05
Azithromycin induces epidermal differentiation and multivesicular bodies in airway epithelia 2.01
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 1.96
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 1.96
Small-molecule targeting of brachyury transcription factor addiction in chordoma [rnaseq_compound] 1.88
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 1.87
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 1.86
Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival 1.85
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability [RNA-seq] 1.84
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability 1.84
Dual RNA-seq – High-resolution comparative Dual RNA-seq time-course 1.81
Dual RNA-seq of diverse human, mouse and pig cell-types infected with various Salmonella strains 1.81
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 1.81
An siRNA screen identifies CHD4 as a target for epigenetic therapy 1.78
Transposon-based construction of strand-specific RNA-seq libraries 1.74
Polarized B -cell functions 1.69
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 1.69
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 1.69
RNA seq with AML (NB4) cells upon FTO inhibition 1.66
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 1.53
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 1.53
RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures 1.52
Disruption of the TFAP2A regulatory domain causes Branchio-Oculo-Facial Syndrome (BOFS) and illuminates pathomechanisms for other human neurocristopathies 1.52
Analysis of gene expression in primary human foreskin keratinocytes +/- HPV16 E7 or PTPN14 knockout 1.49
Transcriptome analysis of human embryonic stem cells (hESCs) upon siRNA-mediated knockdown of hESC-essential genes 1.46
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 1.46
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 1.46
Retinoic acid suppresses MYB in adenoid cystic carcinoma [RNA-seq] 1.4
Retinoic acid suppresses MYB in adenoid cystic carcinoma 1.4
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells (RNA-Seq) 1.4
ETS1 is a genome-wide effector of RAS/ERK signaling in epithelial cells 1.4
Analysis of transcriptomes of healthy donor and CD46 deficient CD8 T cells 1.39
Transcriptome analysis of CD8+ T cells from healthy controls and patients wth CD46 deficiency 1.39
Epigenome Editing by CRISPR/Cas9 Repressors for Silencing of Distal Regulatory Elements 1.38
Functional Comparison of the HGF/Met and MSP/Ron Systems in a Pancreatic Cancer Model 1.37
KDM1A confers invasive and metastatic attributes in lung adenocarcinoma by modulating a non-canonical Integrin ß3-KRAS signaling pathway 1.27
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers 1.25
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers (RNA-Seq) 1.25
Single-cell Transcriptomics reveals multi-step adaptations to endocrine therapy 1.24
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 1.14
Loss of CREBBP results in gene expression repression in lymphoma cells 1.14
CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy 1.14
ChIP-seq and RNA-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells 1.05
RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits 1.05
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 1.02
Function and hormonal regulation of GATA3 in human first trimester placentation 1.0
The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression 0.95
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 0.91
mitoCPR - a surveillance pathway that protects mitochondria in response to mitochondrial import stress 0.91
mitoCPR - a surveillance pathway that protects mitochondria in response to mitochondrial import stress [human] 0.91
NF-κB p65 dimerization and DNA-binding is important for inflammatory gene expression 0.91
RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811. 0.86
Small-molecule targeting of brachyury transcription factor addiction in chordoma 0.81
ChIP-seq and RNA-seq analysis of KMT2D-silenced metastatic melanoma cells 0.79
Transcriptional profiling of SF295 cells following MTF1 knockout by CRISPR/Cas9 0.78
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 0.77
RNA seq analysis of human Fetal and adult derived Enterospheres 0.76
Suppression of the FOXM1 transcriptional program via novel small molecule inhibition 0.75
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity 0.69
DNMT1-associated long non-coding RNA regulate global gene expression and DNA methylation in colon cancer 0.64
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.62
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 0.6
Effect of Polybrominated diphenyl ethers (PBDEs) on gene expression of MCF7 cells 0.59
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 0.59
Nucleotide stress induction of HEXIM1 suppresses melanoma by modulating cancer cell-specific gene transcription [RNA-Seq1] 0.54
Acriflavine inhibits the epithelial-to-mesenchymal transition in vitro in liver and pancreatic cancer cells (part of study on HepG2) 0.49
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 0.34
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.32
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates [RNA-seq] 0.31
Genome-wide mapping of DROSHA cleavage sites on primary microRNAs and novel substrates 0.31
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle 0.26
O-GlcNAc transferase fine-tunes MYC-dependent transcription to promote cell cycle [RNA-seq] 0.26
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 0.26
Transcriptional response of human endocervical epithelial A2EN cells to infection with wild-type or CpoS-deficient Chlamydia trachomatis L2/434/Bu 0.24
HNRNPM-regulated splicing dependencies in prostate cancer 0.22
HNRNPM-regulated splicing dependencies in prostate cancer [RNA-Seq] 0.22
Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes 0.2
RNA sequencing from FOXM1 knockout HEK293T cells reconstituted with FOXM1 isoforms a, b and c. 0.17
DLX3-dependent p53 signaling network controls keratinocyte cell cycle and squamous tumor growth 0.16
DLX3 alters transcriptomic profile of adhesion, cell cycle, and cell death in Squamous Cell Carcinoma Cells 0.16
Genome-wide search for differentially expressed RNAs responsible for the effects induced by Ebola virus replication and transcription 0.16
hsa-miR-503, hsa-miR-103, and hsa-miR-494 genome wide target profiles [RNA-Seq and RIP-Seq] 0.14
Genome-wide hsa-miR-503, hsa-miR-103, and hsa-miR-494 target profiles 0.14
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation 0.09
T-bet recruits P-TEFb to super-enhancers to regulate T helper cell differentiation (RNA-Seq) 0.09
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 0.05
Evolution of an lncRNA leads to a primate specific modulation of alternative splicing 0.05
Loss of ANCO1 repression of AIB1/YAP drives breast cancer progression 0.05
Targeting Spt5-Pol II small-molecule inhibitors uncouple distinct activities and reveal additional regulatory roles 0.01
RNA-seq analysis of PRMT5-regulated genes in irradiated/non-irradiated LNCaP cells 0.01


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