Gene Query: ZCCHC8

Dataset Description Geneva Score
The translation termination factor GSPT1 is a phenotypically relevant off-target of heterobifunctional phthalimide degraders 74.12
Recruiting Endogenous ADARs with Antisense Oligonucleotides to Reprogram the Transcriptome 35.58
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 33.83
Patient-derived luminal breast cancer xenografts with progestins 33.83
Transcriptome analysis in Neobractatin treated cells 29.36
Effect of OVO-like 1 knockdown on global transcript expression in differentiated BeWo trophoblast cells 21.16
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [RNA-Seq] 19.43
EZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation 19.43
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma shRNA Clone TRCN0000005418 targeting RIOK3 with puromycin selection RNAseq 19.4
Gene expression analysis of dengue-infected cells 18.44
Metabolic reprogramming of Kaposi’s sarcoma associated herpes virus infected B-cells in hypoxia 17.16
Loss of CREBBP results in H3K27Ac loss at enhancers and gene expression repression in lymphoma cells 16.62
Loss of CREBBP results in gene expression repression in lymphoma cells 16.62
Human HAP1 cells before and after nutrient deprivation 15.84
Transcriptomic profiling of human HAP1 cells before and after nutrient deprivation 15.84
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 15.03
RNA-seq in HT-29 colorectal cancer cells after F. nucleatum treatment 14.94
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 14.9
RNA-Sequencing experiment for effects of PKF115-584 treatment on four T-ALL cell lines (RPMI8402, HPB-ALL, Jurkat, CCRF-CEM). 14.21
Genome-wide analysis of the Integrator complex 13.67
Genome-wide analysis of the Integrator complex (HTS) 13.67
HeLa transcriptome induction by IFN gamma and indoleamine 2,3-dioxygenase (IDO) 13.27
Gene expression profiling of leukemia cells following asparagine depletion 13.19
Self-organized amniogenesis by human pluripotent stem cells in a biomimetic implantation-like niche 12.97
Sequencing of freshly produced RNA following exposure of cells to DNA damage-inducing UV mimetic 4-hydroxyaminoquinolone (4-NQO) 12.63
Genome-wide view of the impact of Spt5-Pol II inhibitors (SPIs) on mRNA levels [RNA-Seq 2h] 12.56
DRB/GRO-Seq -/+ UV 12.14
Overexpression of UGT2B17 in MEC1 and JVM2 leukemia cell lines 11.95
R430: A potent inbibitor of DNA and RNA viruses 11.89
Cohesin and CTCF Differentially Affect the Chromatin Architecture and Gene Expression in Human Cells 11.86
Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells 11.0
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 10.98
RNA-sequencing time course of Human Intestinal Epithelial Cells (HIECs) following knockdown of miR-30bcd using complementary locked nucleic acids 10.97
NR4A1 Inhibition Synergizes with Ibrutinib in Killing Mantle Cell Lymphoma Cells 10.88
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 10.87
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 10.87
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation 10.62
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 10.51
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 10.44
Interaction with WDR5 recruits MYC to a small cohort of genes required for tumor onset and maintenance 10.11
Next Generation RNA Sequencing Analysis of AMPK Wild Type, AMPKα-KO and AMPKα1-2A U2OS cell Transcriptomes 9.87
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 9.81
ADAR1 controls apoptosis of stressed cells by inhibiting Staufen-mediated mRNA decay 9.53
MDM2 and MDM4 are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors 9.47
U1 snRNP telescripting regulates size-function stratified human genome 9.4
PTBP1 excludes UPF1 to protect long 3'UTRs from nonsense-mediated mRNA decay 9.37
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 9.31
Transcriptional profiling of LS1034 cells treated with tepoxalin 9.31
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 9.28
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq SS] 9.27
Next generation sequencing on knockdown of AC093323.3 in lung cancer cells 9.23
m6A-seq data analysis of control and PCIF1 knockdown transcriptome 9.19
LED, a long non-coding RNA activator of enhancer RNAs, is hypermethylated in human cancers 9.03
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors 9.0
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma 8.87
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma (RNA-Seq) 8.87
A role for p53 in the adaptation to glutamine starvation through the expression of Slc1a3 8.83
Transient stabilization, rather than inhibition of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma 8.46
Developmental stage specific chromosome architecture in human erythroid cells 8.33
Developmental stage specific chromosome architecture in human erythroid cells (RNA-seq) 8.33
Global analysis of pre-mRNA subcellular localization upon splicing inhibition by spliceostatin A 8.33
The evolution of N6-methyladenosine in primates 8.23
Nrf2 regulated genes in A549 cells 8.19
Identification of Nrf2 regulated genes by RNA sequencing 8.19
Gene expression in PANC1 cells treated with Rakicidin 8.19
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 8.18
Inhibition of SF3B1 by molecules targeting the spliceosome in Rh18 cells 8.06
DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy 7.78
Transcriptomes analysis for the regulation of Z36 induced autophagy in HeLa cell death 7.63
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 7.5
microRNAs with an AAGUGC seed motif constitute an integral part of a signaling network driving NSCLC cell proliferation 7.49
Capturing the Interactome of Newly Transcribed RNA 7.38
Capturing the Interactome of Newly Transcribed RNA (RICK) 7.38
Tracking of dCas9-methyltransferase footprints 7.32
SETBP1-WT and SETBP1-G870S epigenetic landscapes 7.28
SETBP1-WT and SETBP1-G870S transcriptional profiles [RNA-Seq] 7.28
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression 7.26
DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq) 7.26
Cell-specific expression and function patterns of microRNA-150-5p in liver fibrogenesis 7.04
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 6.92
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 6.92
Subcellular RNA fractions of HSV-1 infected primary human fibroblasts 6.9
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia [RNA-seq] 6.78
CBFb-SMMHC inhibition triggers apoptosis by disrupting MYC chromatin dynamics in acute myeloid leukemia 6.78
Widespread backtracking by RNA pol II is a major effector of gene activation, 5’ pause release, termination and transcription elongation rate 6.76
The RNA-binding profile of Acinus, a peripheral component of the Exon junction complex, reveals its role in splicing regulation 6.7
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 6.69
Propargite, an environmental chemical, interacts with GWAS identified diabetes genes to impact human pancreatic β-cell death 6.57
The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin 6.5
Transcriptomics analysis of gene expression in normal and METTL3 or WTAP deficient Human HeLa cells 6.43
Effect of FGF13 depletion on the H460 cell line 6.31
Transcriptome sequencing after MAGOHB knockdown in MAGOH-deleted or non-deleted cancer cells 6.22
Targets of CDK12 on ZR-75-30 breast cancer cells (RNA-seq) 6.14
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 6.11
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 6.09
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 6.05
BET-Bromodomain Inhibitors Engage The Host Immune System And Regulate Expression Of The Immune Checkpoint Ligand PD-L1 [3mRNA-seq] 6.05
Regulation of mRNA half-life by an inhibitor of human decapping enzyme Dcp2 following transcription shutoff in HEK293T cells 6.03
LncRNA-GAS5 negative regulation of YAP-target genes expression 5.86
Transcriptional changes in pancreatic cancer cells associated with gemcitabine resistance 5.85
Targeting MTHFD2 in Acute Myeloid Leukemia 5.84
Dual inhibition of HDMX and HDM2 as a Therapeutic Strategy in Leukemia 5.83
Transcriptome analysis-identified long noncoding RNA CRNDE in maintaining endothelial cell proliferation, migration, and tube formation 5.7
CXCR4 regulates extra-medullary myeloma through epithelial-mesenchymal transition-like transcriptional activation 5.61
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma [RNA-seq] 5.55
Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma 5.55
Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML 5.51
The ARID1A tumor suppressor controls global transcription via pausing of RNA Polymerase II 5.45
TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma 5.44
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 5.4
Mitochondrial hypoxic stress induces RNA editing by APOBEC3G in lymphocytes 5.38
Human blood CD1c⁺ dendritic cells encompass CD5-high and CD5-low subsets that differ significantly in phenotype, gene expression and functions 5.34
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (chromatin-bound RNA-seq) 5.25
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression 5.21
A global identification of PUM1 and PUM2 mRNA targets and their protein cofactors in human seminoma TCam-2 cells 5.2
Transcriptomic and gene ontology profiling of the human corneal cell types 5.13
CRISPR adenine and cytosine base editors with reduced RNA off-target activities [CBE] 5.11
CRISPR adenine and cytosine base editors with reduced RNA off-target activities 5.11
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 5.08
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 5.02
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma [RNA-seq] 4.97
Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma 4.97
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells 4.94
VAMP8 contributes to TRIM6-mediated type-I interferon antiviral response upon West Nile virus (WNV) infection 4.93
RNA-seq profiling of the human neutrophil genome during PMA- and E. coli encounter-induced activation 4.86
Human neutrophil genome during PMA- and E. coli encounter-induced activation 4.86
ATF4 inhibition by p62 represses stromal metabolic reprogramming and tumorigenesis II 4.72
Ultracentifugation and nanoscale deterministic lateral displacement (nanoDLD) of samples for exRNA analysis 4.7
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 4.69
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 4.68
Small molecule targets TMED9, promotes lysosomal degradation to reverse proteinopathy 4.67
Major roles of cyclobutane pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation 4.66
Differential mRNA expression upon 9p21 deletion in HEK TE single-cell derived clones 4.61
Loss of 9p21 regulatory hub promotes kidney cancer progression by upregulating HOXB13 4.61
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion [12Z_RNA-seq] 4.59
Transciptome profiling of NoDice and RNaseIII null cells prior to and after polyIC treatment 4.58
Global unleashing of transcription elongation waves in response to genotoxic stress restricts somatic mutation rate 4.58
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 4.56
Transcriptome-wide analysis links the short-term expression of the b isoforms of T-cell intracellular antigens to protective proteostasis-mediated survival and quiescence 4.51
RNA-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 4.49
RNA-sequencing and MeDIP-sequencing of shSRC-1 and shNT tamoxifen treated LY2 cells 4.49
MicroRNA-125a-5p overexpression in human macrophages 4.48
RNA polymerase in pre-B-ALL cell lines 4.47
Epigenetic silencing of the tumor suppressor RASSF4 favors multiple myeloma progression 4.47
Identification of a LIF-responsive replication-competent human β cell 4.46
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 4.44
Transcriptome analysis of human immortilized astrocytes reprogrammed into dopaminergic neurons 4.42
Differentially expressed genes post knock down of lincDUSP26 4.32
Gene expression analysis upon mtDNA depletion [RNA-seq] 4.32
Gene expression analysis upon mtDNA depletion 4.32
A cell-permeable stapled peptide inhibitor of the estrogen receptor/coactivator interaction 4.31
mRNA expression profile of Lymphocytes 4.31
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies [RNA-Seq] 4.29
Discovery of first-in-class reversible dual small molecule inhibitors against G9a and DNMTs with in vivo activity in hematological malignancies 4.29
Mutually Exclusive CBC-Containing Complexes Contribute to RNA Fate. 4.29
Interactions of aCPs with Cytosine-rich Polypyrimidine Tracts Enhance Splicing of Cassette Exons 4.26
Single-cell transcription profiling in KS1 patient iPSCs and NPCs 4.25
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 4.24
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 4.24
Uridylation by TUT4 and TUT7 marks mRNA for degradation 4.23
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line [RNA-Seq] 4.22
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line 4.22
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation [RNA-Seq rescue_SS] 4.21
4.19
Global transcriptional profiling changes upon knockout of USP22 in human Non-small cell lung cancer cells 4.18
In Vivo Chemical Screen Nominates Valproic Acid as Pharmacologic Modulator of Hematopoietic Stem and Progenitor Cell Activity 4.17
RNA-seq analysis of HT-29, MCF10A, and MDA-MB-436 cells 4.16
shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 reveals set of genes potentially coregulated by MED25 and ETV4 4.13
Genome-wide occupancy of FLAG-MED25 and ETV4 and expression profiling of shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 4.13
Structure and degradation of circular RNAs regulate PKR activation in innate immunity 4.11
Lysine benzoylation is a novel histone mark 4.11
Lysine benzoylation is a novel histone mark [RNA-seq] 4.11
RNAseq Analysis in glioblastoma cells treated with Mepazine 4.11
A549 cells and MSR-A549 cells 4.09
mRNA expression profile of A549 cells and MSR-A549 cells with or without JQ1 treatment 4.09
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells (RNA-seq) 4.08
Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells 4.08
Simultaneous and systematic analysis of cellular and viral gene expression during Enterovirus 71-induced host shutoff 4.06
Modulation of SF3B1 causes global intron retention and downregulation of the B-cell receptor pathway in chronic lymphocytic leukemia 4.05
Effect of drugs on transcriptomic profiles 4.03
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells 4.02
Dioxin and AHR impairs mesoderm gene expression and cardiac differentiation in human embryonic stem cells (RNA-Seq) 4.02
RNA-seq, ChIP-seq and single cell RNA-seq of human skin Langerhans cells 4.0
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 3.98
RNA sequence of mRNA in HUVEC cells after depleting EGFL6 3.98
The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways 3.96
Biological effect of chronic mistranslation in mammalian cells 3.96
Evolved Labels of Placental Invasion in Human and Bovine Endometrial Stroma 3.93
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq] 3.92
IDH3a KO RNA-seq 3.91
IRF1 regulates IFN dependent and independent gene expression 3.9
LNCaP treated with iBET 3.9
Plasma cell mitochondrial pyruvate import controls the duration of humoral immunity. 3.9
Direct Isolation and Characterization of Human Nephron Progenitors. 3.88
Mouse Dux is myotoxic and shares partial functional homology with its human paralog DUX4 3.87
An RNA-centric dissection of host complexes controlling flavivirus infection 3.86
An RNA-centric dissection of host complexes controlling flavivirus infection [RNA-Seq] 3.86
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin 3.85
Inherent DNA binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin (RNA-seq) 3.85
Gene expression and 4sUDRB-seq for NF90/NF110 of human scramble and KD HeLa cells. 3.85
mRNA Sequencing of Human PromoCells Using Random Primed mRNA-Sequencing Technique 3.85
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 3.85
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 3.85
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 3.84
Human Nonsense-Mediated RNA Decay Initiates Widely by Endonucleolysis and Targets snoRNA Host Genes 3.83
Differential effects of estrogen receptor beta isoforms on glioblastoma progression 3.82
Seletive inhibition of CDK9 in DLBCL cell lines 3.79
Polarized B -cell functions 3.78
Single cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid  during virologically suppressed HIV 3.76
RNA-Seq analysis of JIB-04 effects on global cellular transcription and HIV in 2D10 T cells 3.75
CD73 knockdown effect in pancreatic cancer cell lines 3.71
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer [RNA-seq] 3.68
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer 3.68
IGF2BP3 controls cancer cell invasiveness by modulation RISC function 3.67
Single-cell analysis reveals stochastic regulation of type I IFN production by plasmacytoid dendritic cells and identifies host-derived environmental cues as amplifier of type I IFN production 3.66
Bach1 Regulates the Self-renewal and Mesendodermal Differentiation of Human Embryonic Stem Cells 3.65
Human Adult Sorted Live Cell Erythroblasts transduced with Sigma non-targeting shRNA negative control (SHC002V) with puromycin selection RNAseq 3.65
RNA sequencing of GlyH-101-treated MCF-7 cell line 3.65
The CDK7 Inhibitor THZ1 Alters RNA Polymerase Dynamics at the 5’ and 3’ Ends of Genes 3.64
RNA-seq after siRNA targeting DDX24 applied to iHUVECs cell lines 3.62
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 3.62
mRNA profiles of JMJD3 overexpression- and JMJD3 knockout- HL-60 cells 3.61
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis 3.61
EZH2 and BCL6 cooperate to assemble CBX8-BCOR Polycomb complex to repress bivalent promoters, mediate germinal center formation and promote lymphomagenesis [RNA-seq] 3.61
UV_24h_GRO-Seq 3.6
Therapeutic targeting of GCB- and ABC-DLBCLs by rationally designed BCL6 inhibitors 3.59
Targeted enhancer activation by a subunit of the integrator complex 3.57
H3K27Ac in MCF7 Y537S ER mutant cells and RNAseq with and without treatment with THZ1 3.56
Meta-organization of Translation Centers Revealed by Proximity Mapping of Endoplasmic Reticulum Ribosome Interactors 3.55
Genetic and pharmacological restoration of TET2 function blocks stem cell self-renewal and progression of leukemia 3.54
RNA-sequencing of human leukemia cells and mouse hematopoietic progenitors 3.54
Transcriptomic analysis of acute mitochondrial pyruvate carrier inhibition using UK5099 in ABL prostate cancer cells 3.54
Primate transcript and protein expression levels evolve under compensatory selection pressures 3.53
Genetic disarray follows mutant KLF1-E325K expression in a congenital dyserythropoietic anemia patient 3.52
Generation of KRAS signatures using immortalized isogenic lung cells. 3.5
hnRNP L protects mRNAs from nonsense-mediated mRNA decay 3.49
Polysome profiling RNAseq of cells transfected with an oligonucleotide targeting the ES6S region of the 40S subunit 3.48
Bioinformatics analysis of transcriptome related to blood stasis syndrome in diabetes mellitus patients 3.46
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer 3.46
Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer (RNA-Seq) 3.46
RNASeq of MV4;11 cells transduced with scramble shRNA or BRD4 shRNA in combination with DMSO or SGC0946 3.44
Gene expression in GBM with Cav3.2 inhibition 3.43
Quantitative Analysis of p53 and/or TGFBR2 Knockdown Endothelial Transcriptomes after Irradiation 3.41
Transcriptomics analysis of gene expression in multiple human and mouse cells and tissues 3.36
ARID1A and PI3-Kinase pathway mutations in the endometrium drive epithelial transdifferentiation and collective invasion 3.34
Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells 3.33
The effects of chemokines CCL2/7 on MDA-MB-231-FOXC1 cells 3.33
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 3.31
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 3.31
CpG dinucleotides introduced into gag can inhibit HIV-1 gene expression by modulating pre-mRNA splicing 3.29
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia 3.28
SNHG15 is a bifunctional MYC-regulated noncoding locus encoding a lncRNA that promotes cell proliferation, invasion and drug resistance in colorectal cancer by interacting with AIF 3.28
Molecular Signatures Associated with ZIKV Exposure in Human Cortical Neural Progenitors 3.27
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival 3.26
RNA splicing alteration on glioblastoma and normal neural stem cells 3.24
SLAM-seq for K562 endogenous mRNA decay 3.23
MLL-AF4 binds directly to a BCL-2 specific enhancer and impacts H3K27 acetylation 3.22
LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs [GRO-seq II] 3.2
4sU-seq of HFF exposed to salt and heat stress 3.2
ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing 3.19
Expression data from A2780 cells treated with DMSO, Olaparib(Ola), Palbociclib(PD), and their combination (Ola/PD) 3.19
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (separate infection) 3.18
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [ChrRNA-seq] 3.16
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 3.15
Influenza Vaccination Primes Human Myeloid Cell Cytokine Secretion and Natural Killer Cell Function 3.09
Gene expression analysis of CD4+ and CD4- ILC1 subsets by RNAseq 3.04
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers (RNA-Seq) 3.03
Transcription factor p63 bookmarks genomic loci in epithelial cells and regulates a subset of target genes during epidermal differentiation through dynamic enhancers 3.03
Gene expression by high-throughput sequencing of T47D-MTVL human breast cancer cells upon H1.4 knock-down and multiple H1 variants 3.0
Paxillin regulates genomic networks in prostate cancer [PC3] 2.99
RNA-Seq of CD34+ Bone Marrow Progenitors from Healthy Donors 2.99
Quantitative mass spectrometry-based proteomics reveals the dynamic protein landscape during initiation of human Th17 cell polarization 2.98
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 2.98
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 2.98
HNF1A deficiency impairs β-cell fate, granule maturation and function 2.96
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. 2.96
Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear RNA 2.94
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons 2.92
Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons [RNA-Seq] 2.92
Discovery of Drug Candidates that Inhibit and Eliminate Zika Virus Infection in Fetal and Adult Brain 2.9
Hijacking of stress response machinery by oncogenes in acute leukaemia 2.9
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 2.9
RNA m5C Methylation in breast cancer using MeRIP-Seq 2.89
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 2.88
Mapping interactions for the TNIP2 hub protein 2.87
DIGIT regulates endoderm differentiation of human embryonic stem cells 2.87
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury 2.84
Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury [human iPS] 2.84
NKX2.2 2.84
RNA-Seq analysis of NKX2.2 knockdown in human pancreatic islets 2.84
Identification of miR-100 and miR-125b targets by AGO2 RIP-seq and RNA-seq after ectopic expression of miR-100 or miR-125b and evaluation of the TGFb expression signature in PANC-1 cells by RNA-seq 2.83
Human Adult Sorted Live Cell Erythroblasts RNA-Seq. 2.83
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 2.82
Knockout human reveal an essential role for Paternally Expressed 10 (PEG10) in JEG3 cell line development 2.81
The pause-initiation limit restricts transcription activation in human cells 2.77
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 2.76
RNA-Seq from human ILC transitional populations 2.75
Expression profiling of ILC transitional populations and Aiolos accessability and H3K27ac histone modifications in transfected MNK3 cells 2.75
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 2: scRNA-seq) 2.75
Poly(ADP-ribose) polymerase 1 is necessary for coactivating hypoxia-inducible factor-1-dependent gene expression by Epstein-Barr virus latent membrane protein 1 2.72
Sirt6 Oncogene Mediates PI3K/Akt Signaling Activation in Diffuse Large B-Cell Lymphoma 2.71
Transcriptome analysis in a radiosensitive and a radioresistant cell line after ionizing radiation 2.7
Single-cell analysis of human kidney organoids 2.7
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 2.66
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 2.66
Resistance to BET inhibitor leads to new therapeutic vulnerabilities in castration resistant prostate cancer 2.65
Evaluation of RNA amplification and RNA-Seq library preparation protocols for spermatozoa RNA profiling 2.64
Loss of Function Mutations in ETS2 Repressor Factor (ERF) Reveal a Balance Between Positive and Negative ETS Factors Controlling Prostate Oncogenesis [22PC RNA-seq] 2.63
Transcriptome analysis of Jurkat T-ALL clones from control and CBAP-knockdown/knockout sets 2.63
Integrin αvβ3 acting as membrane receptor for thyroid hormones mediates angiogenesis in malignant T cells 2.62
Impact of GDF15 expression of ovarian cancer cell on stroma and Cisplatin responses 2.6
FMRP-associated MOV10 facilitates and antagonizes miRNA-mediated regulation 2.54
Transcriptome-wide identification of splicing defects upon XAB2 knockdown 2.52
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (ChIP-seq & RNA-seq datasets) 2.51
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 2.47
Genome-wide profile of cJun and p27 and gene expression profile in breast cancer cells 2.45
Gene expression profile in breast cancer cells 2.45
Genome-wide analysis of Dengue virus 2 infected cells 2.44
Locally transplanted human urine-induced nephron progenitor cells contribute to renal repair in mice kidney with diabetic nephropathy 2.44
Transcriptional profiling of PBMC from patients with aGvHD and patients without aGvHD after alloHSCT 2.44
RNAseq Study in CC-671 Treated Cal-51 Cells 2.44
FBP2 inhibits sarcoma progression by restraining mitochondrial biogenesis 2.43
Potent and targeted activation of HIV-1 using the CRISPR/Cas9 activator Complex 2.42
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 2.41
A549 cell transcriptome responses to infection with H7N9 influenza virus 2.4
RNA sequencing of human macrophages treated with iron chelator deferiprone (DEF), with and without lipopolysaccharide (LPS) 2.39
RNA-sequencing of bulk CD19+ Thymic B cells from young (3 month - 4 year) and old (42 - 61 years) humans 2.37
RNA-sequencing of bulk CD19+ Thymic B cells from mice and humans 2.37
A single-cell atlas of the human cortex reveals drivers of transcriptional changes in Alzheimer’s disease in specific cell subpopulations 2.36
The immediate impact of exoribonucleolysis on nuclear RNA processing, turnover and transcriptional control revealed by rapid depletion of DIS3, EXOSC10 or XRN2 from human cells 2.36
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 2.35
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 2.34
The LINC01138 Drives Malignancies via Activating Arginine Methyltransferase 5 in Hepatocellular Carcinoma 2.34
Novel Form of JARID2 is Required to Regulate Differentiation in Keratinocytes. 2.33
LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs 2.32
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway [RNA-Seq] 2.31
RC3H1 posttranscriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-kB pathway 2.31
SnapShot-Seq: a method for extracting genome-wide, in vivo mRNA dynamics from a single total RNA sample 2.26
The IMiDs, through loss of Ikaros and Aiolos, primes myeloma cells for daratumumab mediated killing by upregulation of CD38 2.25
Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. 2.25
Effect of low-dose sorafenib and alkylating agents in inflammation and angiogenesis in breast cancer 2.24
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 2.23
Disruption of GRIN2B impairs differentiation in human neurons 2.21
Profiles of ribosome-associated mRNAs regulated by expression of wild-type (WT) or R534H variant of DDX3 with or without Sodium Arsenite treatment 2.2
Total RNA profiles associated with DDX3 wild-type (WT) or R534H variant expression with or without sodium arsenite treatment [RNA-seq] 2.2
Interactome (iCLIP) and Translatome ( Polysome profiling) of Musashi 2 (MSI2) targets in K562 2.18
Inhibition of ERG Activity in Patient Derived Prostate Cancer Xenografts using the Small Molecule Inhibitor YK-4-279 2.14
Assessing the impact of loss of ATF7IP and SETDB1 on the transcriptome 2.14
ATF7IP-mediated stabilization of the histone methyltransferase SETDB1 is essential for heterochromatin formation by the HUSH complex 2.14
Microprocessor mediates transcription termination in long noncoding microRNA genes 2.12
Hepatitis C virus functionally sequesters miR-122 2.12
Hepatitis C virus functionally sequesters miR-122 [RNA-Seq] 2.12
Identification of differentially spliced genes by wild type or S34F mutation of U2AF1 2.12
Binding to SMN2 pre-mRNA-Protein complex elicits specificity for small molecule splicing modifiers 2.09
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 2.07
SPOP mutation confers intrinsic BET inhibitor resistance in prostate cancer 2.06
Transcriptome-wide modulation of splicing by the exon junction complex 2.05
TT-Seq captures the human transient transcriptome 2.04
Huntingtin aggregation impairs autophagy leading to Argonaute-2 accumulation and global microRNA dysregulation 2.04
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma 2.04
‘Naïve’ ESRRB+ iPSCs with the capacity for rapid neural differentiation 2.0
Transcriptome analysis of peripheral blood monocytes 2.0
Cis-SAGe fusion RNAs in transcription splicing factors knocking-down 293T cells 2.0
Modulation of nonsense-mediated decay by rapamycin 1.98
Transcriptomic analysis of the effect of histone H4 K31R mutation in U2OS cells 1.95
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells 1.94
Cell differentiation grade determines distinct FOXA2 contributions to the cis-regulatory networks of pancreatic cancer cells [RNA-seq] 1.94
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 1.9
CRISPR activation of long non-coding RNAs transiently expressed during cortical neuron differentiation associated with Field, et al, Stem Cell Reports 2018 1.88
Rate of elongation by RNA polymerase II is influenced by specific gene features and histone modifications 1.86
Single-Cell Transcriptome Analysis of Lineage Diversity and Microenvironment in High-Grade Glioma 1.84
mRNA expression levels in splenic human mononuclear cells of mock- and HIV-1-infected humanized mice 1.83
An integrative analysis of non-coding regulatory DNA variations associated with autism 1.83
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability 1.81
Selective Inhibition of the Second Bromodomain of BET Family Maintains Anti-Tumor Efficacy and Improves Tolerability (22RV1 RNA-seq) 1.81
ADAR1-editing of cellular and measles virus-derived duplex RNA 1.8
ADAR1-editing in HeLa, p150-KO and ADAR1-KO transcriptomes 1.8
The identification of RBM47 binding sites and RBM47-dependent alternative splicing events in brain metastatic breast cancer cells 1.79
Identification of alternatively spliced transcripts in brain metastatic derivatives of MDA-MB-231 breast cancer cells in response to RBM47 expression 1.79
Studying the selectivity of a targeted small molecule degrading a hypoxia-associated non-coding RNA 1.79
Cellular recruitment by podocyte-derived pro-migratory factors in assembly of the human renal filter 1.77
Genome-Wide Transcriptional Effects of the Anti-Cancer Agent Camptothecin 1.75
Leucegene: AML sequencing (part 6) 1.73
Controlling for gene expression changes in transcription factor protein networks. 1.69
CUREfast: Accelerating research with families 1.67
The effect of doxycycline-induced expression of host-cell-factor 2 (HCF-2) proteins on the global gene expression in HEK-293 cells 1.66
Oxaliplatin resistance is enhanced by saracatinib via upregulation of ABCG1 and Wnt/β-catenin signaling in hepatocellular carcinoma 1.66
quanTIseq: quantifying immune contexture of human tumors 1.65
Transcriptome-wide profiling of poly(A)-tail length, translation efficiency and mRNA stability using TED-seq, mRNA-seq, Ribo-seq and PRO-seq in ER stress conditions 1.65
A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (RNA-Seq) 1.64
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 1.64
4sUDRB-seq: measuring transcription elongation and initiation genomewide 1.63
Functional significance of the HIV-1 Tat signature amino acid residues 1.6
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells [GRO-seq] 1.59
TNFα Signaling Exposes Latent Estrogen Receptor Binding Sites in Breast Cancer Cells 1.59
Selective roles of vertebrate PCF11 in premature and full-length transcript termination (human 3' mRNA-seq) 1.55
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 1.53
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 1.53
LIN28A Over-expression RNAseq 1.52
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [NALM6 RNA-Seq] 1.52
Functional TRIM24 degraders via conjugation of ineffectual bromodomain and VHL ligands [RNA-seq] 1.51
Dissecting cell composition and cell-cell interaction network of human disease heart tissue by single-cell sequencing 1.49
Gene expression profiles of tumor-infiltrating CD8 T cells in hepatocellular carcinoma 1.49
The DPYSL2 gene connects mTOR and schizophrenia 1.49
RNA-seq analysis of PRMT5-regulated genes in irradiated/non-irradiated LNCaP cells 1.48
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 1.46
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 1.46
Exploring ILF2 regulatory genes by next-generation sequencing 1.45
Noncoding regions are the main source of targetable tumor-specific antigens 1.45
BCL6 confers KRAS-mutant NSCLCs resistance to BET inhibitors 1.43
Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) 1.39
Genome wide association study of bone size yields eleven loci that also affect height, bone density, osteoarthritis and fractures 1.39
Genome-wide mapping of TEL-AML1 targets in acute leukemia 1.37
PRMT5 Interacts with the BCL6 Oncoprotein and is Required for Germinal Center Formation and Lymphoma Cell Survival 1.37
RNA sequencing to study transcriptomic changes in DLD-1 (colorectal adenocarcinoma) cells exposed to soft polyacrylamide matrices (~2 kPa and ~55 kPa) for short time scale of 90 minutes 1.35
Total RNA was extracted from three samples of CD33 CAR or control T cells from three different donors 1.34
Transcriptomics analysis of gene expression in normal and YTHDC1, SRSF1, SRSF3, SRSF7, SRSF9 or SRSF10 deficient human HeLa cells 1.32
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 1.3
Quantitative Proteomics Reveals a Unique Wiring of Signaling Pathways that Protects Human Regulatory T Cell Identity 1.29
Nickel exposure induces persistent mesenchymal phenotype in human lung epithelial cells through epigenetic activation of ZEB1 1.25
Gene expression from AsPC-1 cells treated with PTC596 and DMSO 1.23
UV-Irradiation Induces a Noncoding RNA that Functionally Opposes the Protein Encoded by the Same Gene 1.16
Determining mRNA half-lives on a transcriptome-wide scale 1.15
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 1.15
Ewing sarcoma resistance to SP-2509 is not mediated through KDM1A/LSD1 mutation II 1.09
Profiling of lung tumor-infiltrating CD8 T cells according to their expression status of CD39 1.06
The ZZ-type zinc finger of ZZZ3 modulates the ATAC complex-mediated histone acetylation and gene activation 1.06
Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice 1.05
miR-155 plays a crucial role in ALS and is an immune therapeutic target [RNA-Seq] 1.05
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 1.05
The hepatitis C viral protein NS5A stabilizes growth-regulatory human transcripts 1.02
Transcriptomic profiling of O-GlcNAcylated mRNA-protein complexes by using OG-CLAP in HeLa cells. 0.99
An intramolecular salt bridge linking TDP43’s RNA recognition motifs dictates RNA binding, protein stability and TDP43-dependent neurodegeneration 0.95
Trisomy of a ‘Down syndrome critical region’ globally amplifies transcription via HMGN1 overexpression [SLAM-Seq] 0.92
Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq 0.9
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 0.89
Transcriptome analysis of V336Y mutant mitochondrial ribosomal protein in human HEK293 cell line 0.88
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 0.88
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 0.88
Pseudouridylation of tRNA-derived fragments steers translation control in stem cells [Polysome-Seq] 0.87
RNA-sequencing analysis of glucose and acetate regulated transcripts in glioblastoma cells 0.85
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 0.83
Aging Human Hematopoietic Stem Cells Manifest Profound Epigenetic Reprogramming of Enhancers That May Predispose to Leukemia (RNA-Seq of HSCe) 0.82
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 0.82
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 0.82
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.79
Domain-focused CRISPR-screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells 0.78
High-resolution comparative analysis of great ape genomes 0.78
Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors [Modifications - screen] 0.77
Human Cord Blood Sorted Live Cell Erythroblasts RNA-Seq 0.76
The RNA exosome nuclease complex regulates human embryonic stem cell differentiation 0.75
Identification and characterization of circular RNAs as a new class of putative biomarkers in human blood 0.7
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 0.69
Global transcriptome analysis in the MYCN-amplified neuroblastoma cell line IMR5-75 upon inducible MYCN-knockdown 0.66
Comparative gene expression profiling of MHH-CALL4 cells subject to pharmacological JAK2 inhibitor treatment (ruxolitinib or CHZ868) or shRNA-mediated JAK2 depletion in vitro 0.63
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias 0.63
Allergen-specific immunotherapy modulates the balance of circulating Tfh and Tfr cells 0.61
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 0.6
RNA-Seq of SLNCR1 over-expression in the melanoma cell line A375 0.6
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [RNA-Seq] 0.59
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration 0.57
Induction of Cardiomyocyte Proliferation [pz-822_human] 0.57
Transcriptome of human ILC2s; primary vs IL-1b-primed 0.55
Myc activation coordinates gene transcription and protein translation responses 0.54
A SRp55-regulated alternative splicing network controls pancreatic beta cell survival and function 0.53
HEXIM1 is induced by DHODH inhibition to suppress melanoma [Gro-Seq] 0.53
HEXIM1 is induced by DHODH inhibition to suppress melanoma 0.53
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.52
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.52
Knock-down of Ror1 in MDA-MB-231 cell line decreases cell invasiveness 0.49
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex (Gro-seq) 0.48
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex 0.48
C19ORF66 broadly escapes viral-induced endonuclease cleavage and restricts Kaposi’s Sarcoma Associated Herpesvirus (KSHV) 0.46
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 0.45
Multiplexed engineering and analysis of endogenous enhancer activity in single cells: Mosaic-Seq of beta-globin locus (pooled infection) 0.41
Radiomic and gEnomic approaches for the enhanced DIagnosis of REnal Cancer (REDIRECt): A translational pilot study 0.37
m6A level and isoform characterization sequencing (m6A-LAIC-seq) reveal the census and complexity of the m6A epitranscriptome 0.28
Interphase condensins regulate ligand-depedent enhancer activation (GRO-seq) 0.28
Interphase condensins regulate ligand-depedent enhancer activation 0.28
Human MAIT cells exit peripheral tissues and re-circulate via lymph in steady state conditions 0.24
FOXO1 is an oncogenic mediator in AML1-ETO leukemia 0.22
RNA seq analysis of human macrophages after treatment of glimepiride versus empagliflozin. 0.2
Transcriptional response to the HSP70 inhibitor MAL3-101 in parental rhabdomyosarcoma cells and isogenic acquired-resistance lines. 0.18
Impact on erythroid progenitor type on erythroid differntiation 0.17
Primate-specific gene TMEM14B promotes cortical expansion and folding 0.16
Aging-associated patterns in the expression of human endogenous retroviruses 0.15
RNA-seq of primary patient AML samples 0.13
Distinct structural classes of activating FOXA1 alterations in prostate cancer progression 0.11
RNA-Seq characterization of human H1-derived NPC differentiation timecourse 0.11
RB tumor suppressor promotes cancer immunity through downregulating PD-L1 expression 0.11
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 0.09
Non-IG Aberrations of FOXP1 in B-Cell Malignancies Lead to an Aberrant Expression of N-Truncated Isoforms of FOXP1 0.09
Non-inflammatory tumor microenvironment of Diffuse Intrinsic Pontine Glioma (DIPG) 0.08
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.07
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 0.07
Oncogenic Antisense LncRNA P14AS Regulates Expression of ANRIL through AUF1 Binding 0.05
Critical role for Lymphocytes in Producing FLT3LG in Tumors and Driving Checkpoint Therapy-Receptive Immune Microenvironments 0.04
YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction. 0.04
YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction [RNA-seq] 0.04
Uridylation by TUT4 and TUT7 marks mRNA for degradation [RNA-Seq] 0.03


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