Gene Query: ZNF558

Dataset Description Geneva Score
Transcriptomic profiling of O-GlcNAcylated mRNA-protein complexes by using OG-CLAP in HeLa cells. 19.77
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 17.0
Meta-organization of Translation Centers Revealed by Proximity Mapping of Endoplasmic Reticulum Ribosome Interactors 16.15
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 15.98
Patient-derived luminal breast cancer xenografts with progestins 15.98
A potent and selective small-molecule degrader of STAT3 achieves complete tumor regression in vivo 14.2
Effect of Hotair overexpression in human breast cancer cell lines 13.18
RNAseq data from SCCOHT1 and OVCAR8 ovarian cancer cells treated with BET inhibitors 10.89
Expression data from fresh human embryonic lung epithelial tip and stalk cells and cultured organoids derived from tip and stalk. 9.46
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 9.25
Heterozygous p53-R280T mutation promotes proliferation of NPC cells through activating PI3K/Akt signaling pathway 8.6
Post-transcriptional remodelling is temporally deregulated during motor neurogenesis in human ALS models 8.47
Mllt3 Governs Self-Renewal And Engraftment Of Human Hematopoietic Stem Cells 8.0
RNA-seq of MLLT3-overexpressing cultued HSPC, compared to non-overexpressing and uncutured FL-HSPC [RNAseq_MLLT3_OE] 8.0
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 7.43
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors That Can Function as a Cell of Origin for Prostate Cancer 7.43
Expression profile of HNF1A knockdown and overexpression in 22RV1 and LNCaP cells respectively 7.1
Integrative analysis identifies targetable CREB1/FoxA1 transcriptional co-regulation as a predictor of prostate cancer recurrence 6.66
An Alternative Splicing Event Amplifies Evolutionary Differences Between Vertebrates 6.24
RNA-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 6.21
RNA-Seq and ATAC-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 6.21
LMO1 Synergizes with MYCN to Promotes Neuroblastoma Initiation and Metastasis 6.2
Epigenomic conservation of transposable element silencing [RNA-seq] 6.15
Epigenomic conservation of transposable element silencing 6.15
U2AF1 mutations alter splice site recognition in hematological malignancies 6.03
mRNA sequencing of clinical-grade neural stem cells derived from human ES cells 5.79
Proliferation-correlated expression 5.74
Hypoxic transcriptome of SQ20B human head and neck cancer cells 5.74
Polyol pathway links glucose metabolism to the aggressiveness of cancer cells 5.73
Deep sequencing of transcript levels in pluripotent stem cells and their differentiated derivatives in all three germ layers 5.64
Next generation sequencing analysis of transcriptomes at different timepoints after chlorprothixene treatment in NB4 and Kasumi-1 cells 5.61
Transcriptome analysis on TDP43 and SRSF3 downstream genes and binding RNAs in MDA-MB231 cells by Next Generation Sequencing 5.6
Gene expression profile of human iPSC-derived nephron progenitor cells 5.56
Enriched EWSR1 and EWS-FLI1 RNA-seq of HNRNPH1-silenced TC32 Ewing sarcoma and 293T human embryonic kidney cells. 5.48
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome 5.45
S-adenosyl-methionine treatment selectively block liver cancer cell lines transformation and invasiveness by alterations of cancer- and invasion specific transcriptome and methylome (RNA-Seq) 5.45
Global Promotion of Alternative Internal Exon Usage by mRNA 3' End Formation Factors 5.36
Global Regulation of Alternative Internal Exon Usage by mRNA 3' End Formation Factors [RNA-Seq] 5.36
The lipodystrophic hotspot lamin A p.R482W mutation deregulates the mesodermal inducer T/Brachyury and early vascular differentiation gene networks 5.28
Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia [shRNA] 5.21
Studying iPSCs from a hibernating mammal reveals molecular mechanisms of cold resistance in neural tissues 5.16
Induced DNA demethylation, genome instability and transcription 5.09
Impact of DNA demethylation agents (5-azacytidine or vitamin C) on gene expression in glioblastoma HSR-GBM1 cells 5.09
Downregulation of DDX5/DDX17 and REST 4.95
Transcriptome variation among human embryonic stem cell lines impacts on their differentiation 4.92
Transcriptome analysis of H9 hESC derived cerebral organoids 4.88
Transcriptome profiling of self-renewing hESCs and multipotent mesoderm progenitor cells as a function of substrate stiffness 4.76
Expression profile of LNCaP/AR cells with or without HNF4G expression grown for long term in charcoal stripped-serum (CSS) media 4.74
JAG1 Mediated Notch Signaling Regulates Secretory Cell Differentiation of the Human Airway Epithelium 4.74
Loss of CHD1 facilitates oncogenic hijacking of AR during cancer progression 4.73
Loss of CHD1 facilitates oncogenic hijacking of AR during cancer progression [RNA-seq] 4.73
SMN deficiency in spinal muscular atrophy causes widespread intron retention and DNA damage 4.71
Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells 4.7
Transcriptome-wide identification of CELF2 functional targets in T cells 4.61
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer 4.6
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer [RNA-seq] 4.6
The evolution of N6-methyladenosine in primates 4.6
Transcriptome analysis of immature and matured human oocytes from patients of young and advanced maternal age 4.59
RNA-seq analysis of control and NRDE2-depleted breast cancer cells 4.57
PolyA+ RNA-seq in ALL-SIL upon TLX1 knockdown 4.39
RNA Sequencing of default, melanocyte biased and enteric human neural crest populations (NC) and neuroectoderm (CNS) 4.39
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2 [RNA-seq] 4.37
MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network 4.37
Gene expression profiling via RNA sequencing of patient brain tumors cultured in 3D bioengineered cultures 4.27
Transcriptional profile of CAOV2 primary and CAOV2 recurrent cells 4.27
Transcription control by the ENL YEATS domain in acute leukemia 4.19
Transcription control by the ENL YEATS domain in acute leukemia [RNA-seq] 4.19
Integrative transcriptome-wide analyses reveal critical HER2-regulated mRNAs and lincRNAs in HER2+ breast cancer 4.17
RNA-Seq comparative analysis of human neuroblastoma cells before and after their confrontation to the embryonic microenvironment 4.16
Immunophenotyping and Transcriptomic Outcomes in PDX-Derived TNBC Tissue 4.16
Transcriptomic analysis of human iPS cells derived from fragile X syndrome patients during neural differentiation 4.1
RNA-Seq study of Cell lines rendered resistant to idelalisib and ibrutinib 4.06
Temporal activation of NR5A2 and RARγ induce functional human naïve pluripotent state via modulating TGFβ pathway 4.05
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection 4.04
Suppression of ribosomal pausing by eIF5A is necessary to maintain the fidelity of start codon selection (RNA-sequencing) 4.04
FOXP2's impact on the primate transcriptome 3.96
Human TFIIH kinase CDK7 regulates transcription-associated epigenetic modification 3.94
Quantitative Analysis of PPARD Transcriptomes in Colon Cancer Cells by Next Generation Sequencing (NGS) 3.82
Chromatin remodeling mediated by ARID1A is indispensable for normal hematopoiesis in mice (human RNA-Seq) 3.81
The regulartory role of ZCCHC24 in splicing machinery 3.81
The RNA helicase DDX6 regulates self-renewal and differentiation of human and mouse stem cells [RNA-seq] 3.71
Effects of NSUN2 deficiency on the mRNA 5-methylcytosine modification and gene expression profile in HEK293 cells (RNA-Seq) 3.69
Whole transcriptome splicing analysis in isogenic lung epithelial and adenocarcinoma cell lines with or without a recurrent splicing factor mutation, U2AF1 (S34F) 3.66
Dynamics of the human and viral m6A RNA methylomes during HIV-1 infection of T cells 3.64
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 3.64
Comparison of the transcriptome and chromatin state between human cord blood HSC and human iPSC derived hematopoietic progenitor using next-generation sequencing 3.6
Gene expression profiling in lung and breast cancer cells treated by Bloom-specific siRNAs 3.57
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines [RNA-seq] 3.57
Mapping of DHT-responsive or -independent AR-binding sites induced by activated Src in prostate cancer cell lines 3.57
RNA transcriptome analysis of IRF1 and IRF3 knockout in immortalized primary hepatocytes infected with hepatitis A virus 3.56
SUV420H2 knockdown in PANC-1 3.53
Transcription-dependent control of stem cell self-renewal and differentiation by the splicing factor U2AF1 3.53
RING-finger protein 6 amplification activates JAK/STAT3 pathway by modifying SHP-1 ubiquitylation and associates with poor outcome in colorectal cancer 3.52
Codon usage optimization in pluripotent embryonic stem cells [RNA-seq] 3.5
mRNAseq of Huntington's disease and control patient iPSC-derived brain microvascular endothelial cells 3.49
Exploiting drug addiction mechanisms to select against MAPKi resistant melanoma 3.48
Heterogeneous effects of massive hypoxia pathway activation in kidney cancer 3.48
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 3.42
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 3.42
Gene expression changes associated with resistance to tagraxofusp (SL-401) 3.4
Region-specific Innate Antiviral Responses of the Human Epididymis 3.4
Differential gene expression tools exhibit substandard performance for long non-coding RNA-sequencing data 3.35
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 3.35
The effects of U1 snRNA mutation in chronic lymphocytic leukemia cell lines 3.33
Identification of ZEB1-regulated gene expression changes in HCC827 human lung adenocarcinoma cells 3.33
Differential susceptibility of human pleural and peritoneal mesothelial cells to asbestos exposure 3.3
Characterization of parental and rociletinib-resistant derived H1975 cell lines 3.29
shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 reveals set of genes potentially coregulated by MED25 and ETV4 3.29
Genome-wide occupancy of FLAG-MED25 and ETV4 and expression profiling of shRNA-mediated knockdown of ETV4 and MED25 in the prostate cell line PC3 3.29
RNA sequencing of human fibroblasts after SUPT4H1 siRNA treatment 3.28
Analysis of MGE Transcriptomes with or without Ctnnb1 knockout in human through RNA Sequencing 3.28
IGF2BP3 controls cancer cell invasiveness by modulation RISC function 3.26
Analysis of transcrptomes of Danon patient derived hiPSC-cardiomyocytes by RNA-deep Sequencing 3.25
Food-derived Compounds Apigenin and Luteolin Modulate mRNA Splicing of Introns with Weak Splice Sites 3.25
Endometrial epithelial cell transcriptome response to co-culture with adipose stromal cells 3.23
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 3.22
RNA expression following TMPRSS11B overexpression or depletion 3.19
BRG1 governs Glucocorticoid Receptor interactions with chromatin and pioneer factors across the genome 3.18
Gene expression in GBM with Cav3.2 inhibition 3.16
DHX36 resolves G-rich structures in mRNA untranslated region to allow their translation [ChrRNA-seq] 3.12
Enhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest 3.11
Global transcript structure resolution of high gene density genomes through multi-platform data integration: Illumina RNA-Seq 3.08
Isolation and sequencing of AGO-bound RNAs reveals characteristics of stem-loop processing in vivo 3.06
Retinoic acid suppresses MYB in adenoid cystic carcinoma [RNA-seq] 3.06
Retinoic acid suppresses MYB in adenoid cystic carcinoma 3.06
Elucidating the microRNA-203 specific biological processes in glioblastoma cells from comprehensive high-throughput RNA-sequencing transcriptome profiling 3.05
Transcriptional profiling of MDA-MB-231 and its ρ0 cells (lacking mtDNA) after 48h arginine depletion by arginine deiminase (ADI). 2.99
Transcription differences in DLBCL cell lines U2932, DOHH2 on treatment with TK compound compared to DMSO 2.98
Regulartory effect of HNRNPL and LARP on RNA expression in LNCaP prostate cancer cells 2.98
HNRNPL and its RNA Targets in Prostate Cancer 2.98
MPTAC determines APP fragmentation via sensing sulfur amino acid catabolism 2.97
Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes (ALK) 2.94
IL-11 neutralising therapies for the treatment of nonalcoholic steatohepatitis 2.9
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export II 2.89
RNA isoform screens reveal the essentiality and tumor suppressor activity of ultraconserved poison exons 2.86
Genome-wide maps of chromatin state and Gene Expression Profiling in HCT116 cells 2.84
Gene Expression Profiling of WT and KDM3A Knocked out Cell 2.84
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 2.83
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation [bulk RNA-Seq] 2.82
Single-cell epigenomics maps the continuous regulatory landscape of human hematopoietic differentiation 2.82
Differential YAP expression in glioma cells induces cell competition and promotes tumorigenesis 2.81
MYCi361 regulates MYC target genes 2.8
Amiloride, an old diuretic drug, is a potential therapeutic agent for multiple myeloma 2.79
Transcriptomic profiling of normal human cardiac fibroblast treated with halofuginone 2.79
Effect of 48h treatment with 100nM GSK2879552 on T-ALL cell lines HSB2 and RPMI8402 2.78
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes 2.75
DNA breaks and chromatin structural changes enhance the transcription of Autoimmune Regulator target genes [RNA-Seq] 2.75
Capturing the biology of mild versus severe disease in a pluripotent stem cell-based model of Familial Dysautonomia 2.75
Vitamin d receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy 2.74
Apatinib preferentially inhibits Gefitinib-resistant lung cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway 2.74
Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation 2.72
RNA-seq Profiles in RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 2.72
RBPJ Maintains Brain Tumor Initiating Cells through CDK9-mediated Transcriptional Elongation 2.72
Expression data from human perivascular stem cell-derived extracellular vesicles (PSC-EVs) and PSCs 2.7
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival 2.69
AKT Inhibition Promotes Non-autonomous Cancer Cell Survival [RNA-Seq] 2.69
Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML 2.69
CD73 knockdown effect in pancreatic cancer cell lines 2.66
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia (RNA-seq) 2.64
Chromatin Topology Reorganization and Transcription Repression by PML/RARα in Acute Promyeloid Leukemia 2.64
A549 cell transcriptome responses to infection with H7N9 influenza virus 2.62
Human Sandhoff Disease Cerebral Organoids Exhibit Enlarged Size, Increased Cellular Proliferation, and Impaired Differentiation 2.59
SETDB2 links E2A-PBX1 to cell cycle dysregulation in acute leukemia through CDKN2C repression [sequencing] 2.57
Stranded RNA-seq were performed on total RNA following ribosomal RNAs depletion (Ribo-zero removal kit, illumina) for 3 brain , 8 IDHwt and 5 IDHmut glioma samples. 2.56
Discovery of cis-spliced chimeric RNAs between adjacent genes in human prostate cells 2.55
Modeling human brain evolution using induced pluripotent stem cells: comparative analysis of neuronal development in humans and chimpanzees 2.54
Dnmt3a and Dnmt3b associate with enhancers to regulate human epidermal stem cell homeostasis 2.53
Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify 2.52
Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection with Transcriptome Analysis 2.51
N6-methyladenine DNA Modification in Glioblastoma [RNA-seq] 2.47
N6-methyladenine DNA Modification in Glioblastoma 2.47
RNA-seq of tumor cells following angiopellosis extravasation 2.45
O-glcnAc reprograms cellular energetics 2.45
Global gene expression profiles of cardiomyocytes differentiated from human pluripotent stem cells (hiPSC-CMs) in 3D culture exposed to ethanol 2.44
GREB1 amplifies androgen receptor output in prostate cancer and contributes to antiandrogen resistance 2.44
Total RNA-seq in ALL-SIL upon TLX1 knockdown 2.44
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 2.44
Patient iPSC-derived neural stem cells display progressive enlargement of lysosomes and disruptions of glycosaminoglycan pathway and autophagy in concordance with clinical severity of Mucopolysaccharidosis I 2.43
C9orf72 Intermediate Repeats are Associated with Corticobasal Degeneration, Increased C9orf72 Expression and Disruption of Autophagy 2.43
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 2.42
Risk SNPs mediated promoter-enhancer switching promotes prostate cancer progression through lncRNA PCAT19 (RNA-seq data sets) 2.42
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line [RNA-Seq] 2.42
B-cell activating factor (BAFF) stimulation of Burkitt Lymphoma cell line 2.42
Hijacking of stress response machinery by oncogenes in acute leukaemia 2.41
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 2.41
a-synuclein accumulation in an iPSC derived model of early onset sporadic Parkinson’s Disease reveals novel drug targets 2.4
Modulation of ESRP2 and MBNL2 in normal kidney and clear cell renal cell carcinoma cell lines for analysis of stability programs 2.39
Sequencing-based analyses characterize a tumor suppressive role of mir-1271 repressed by DNA hypermethylation in gastric cancer 2.38
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 2.38
Highly-motile versus unsorted MDA-MB-231 breast cancer cells 2.38
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 2.37
mRNA and RNC-mRNA deep sequencing of three hepatocellular carcinoma cell lines 2.37
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 2.36
Transcriptomic hallmarks of tumor plasticity and stromal interactions in brain metastasis 2.36
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 2.31
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes 2.3
Gene expression analysis of the impact of TDP-43 knockout in human cells. 2.3
MDM2 and MDM4 are Therapeutic Vulnerabilities in Malignant Rhabdoid Tumors 2.29
Cystathionine-β-Synthase Promotes Colon Carcinogenesis 2.29
Total RNA-Seq data from leukemic patients with complex structural variants 2.28
Transcriptomic analysis of IPF lung-associated and normal peripheral blood T cells 2.27
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 2.26
Differential RNA-seq analysis comparing APC-defective and APC-restored SW480 colorectal cancer cells 2.26
The effect of insulin on mRNA transcription of human pluripotent stem cells 2.25
Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons 2.24
Improving fibroblast characterization using single-cell RNA sequencing: an optimized tissue disaggregation and data processing pipeline 2.24
Epigenetic silencing of the tumor suppressor RASSF4 favors multiple myeloma progression 2.23
Major roles of cyclobutane pyrimidine dimers, nucleotide excision repair and ATR in the alternative splicing response to UV irradiation 2.22
The β-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner 2.2
Gene expression analysis upon mtDNA depletion 2.2
Gene expression analysis upon mtDNA depletion [RNA-seq] 2.2
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition [RNA-Seq] 2.19
Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition 2.19
Next Generation Sequencing Facilitates Quantitative Analysis of Human Primary and Pluripotent Stem Cell-Derived Epicardial Cell Transcriptomes 2.18
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 2.17
RNA sequencing of CACO-2 cells incubated with Bifidobacteria breve grown on human milk oligosaccharides. 2.15
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 2.14
Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses (Experiment 1: RNA-seq) 2.13
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 2.13
The ribosomal prolyl-hydroxylase OGFOD1 decreases during cardiac differentiation, modulates translation and spliceosomal processes 2.12
Comparing gene expression in iPSC derived RPE from control and AMD donors 2.12
Bromodomain protein BRD4 is a transcriptional repressor of autophagy and lysosomal function 2.09
Polarized B -cell functions 2.08
Activation Dynamics and Immunoglobulin Evolution of Pre-existing and Newly Generated Human Memory B-cell Responses to Influenza Hemagglutinin 2.07
Rational targeting of RNA structure in SMN2 transcripts reverses Spinal Muscular Atrophy molecular phenotypes 2.07
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation 2.06
Identification of an NKX3.1-G9a-UTY regulatory network that controls prostate differentiation (Human_RWPE1_RNA-Seq) 2.06
The mechanism of HHT in treating acute myeloid leukemia on RNA level. 2.05
CHCHD10 gene KO effect in iPSC drived motor neurons 2.04
Deep sequencing of transcript levels of human embryonic stem cell derived mesothelium (epithelial and mesenchymal forms) and mesothelium from neonatal mouse E15.5 of the heart, lung, liver and gut and ChIP-seq data of the mesenchymal form of mesothelium 2.03
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 2.03
RNA seq with AML (NB4) cells upon FTO inhibition 2.03
Tracing transcriptome profiles of human oocyte cultured by growth hormone or not in vitro by single cell RNA-seq 2.02
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 2.02
Transciptomic profiling of human fetal lung samples 2.02
Regulation of hypoxia-inducible factor activity by ZMYND8 2.01
Small molecule targets TMED9, promotes lysosomal degradation to reverse proteinopathy 2.01
Hit-and-run' programing of CAR-T cells using mRNA nanocarriers 2.0
Inhibition of ERG Activity in Patient Derived Prostate Cancer Xenografts using the Small Molecule Inhibitor YK-4-279 1.99
Mutation independent activation of the Notch pathway is associated with Lapatinib resistance in Her2+ breast cancer cell lines 1.99
HeLa transcriptome induction by IFN gamma and indoleamine 2,3-dioxygenase (IDO) 1.98
Profiling in vivo Bone Lesion (IVBL) and Orthotopic tumors by Next Generation Sequencing 1.98
Patient-iPSC-derived kidney organoids show functional validation of a ciliopathic renal phenotype 1.98
Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer 1.97
Illumina Total RNA-seq in HeLa 1.96
hMTR4 plays a central role in creating balanced nuclear RNA pools for degradation and export 1.95
Human pluripotent stem cell-derived brain tumor model uncovered embryonic stem cell signature as a key driver in atypical teratoid/rhabdoid tumor (RNA-Seq) 1.94
Canonical poly(A) polymerase activity promotes the decay of a wide variety of mammalian nuclear RNAs 1.92
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma (RNA-Seq) 1.9
Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma 1.9
LINE-2 transposable elements are a source of functional human microRNAs and target sites 1.9
A histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing 1.9
RNA-seq in untreated and flagellin-treated Human Intestinal Myofibroblast cells (HIMF) 1.88
TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma 1.86
Nonpregnant and term pregnant human myometrial tissues 1.85
Transcriptomic profiles of nonpregnant and term pregnant human myometrial tissues 1.85
P120-catenin dependent glioma-cell networks drive growth and diffuse brain infiltration 1.85
Coordinate regulation of alternative pre-mRNA splicing events by the human RNA chaperone proteins hnRNPA1 and DDX5 1.83
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function 1.83
Epigenetic reprogramming of immune cells in women with PCOS impact genes controlling reproductive function [RNAseq] 1.83
RNA-seq and m6A-seq of AML cells with FTO knockdown or inhibition 1.82
Human iPSC-derived microglia assume a primary microglia-like state after transplantation into the neonatal mouse brain [Single Cell RNAseq] 1.82
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 1.81
Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D 1.79
Pre-mRNA Splicing is Facilitated by an Optimal RNA Polymerase II Elongation Rate 1.79
Adaptation of the Kinome Promotes Resistance to BET Bromodomain Inhibitors in Ovarian Cancer 1.79
EWSR1 influences alternative splicing through direct and indirect mechanisms 1.79
Entrectinib Resistance in a Neuroblastoma Xenograft Model 1.78
Dynamics of Proteo-Transcriptomic Response to HIV-1 Infection 1.77
Paxillin regulates genomic networks in prostate cancer [PC3] 1.77
Comparing oestrogen-responsive genes in endometrial and breast cancer cell lines 1.77
RNA-seq of resting and activated CD4+ T cells +-JQ1 1.76
Cancer-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1 1.75
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 1.74
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. 1.73
Gene expression profiling in follicular lymphoma (FL) samples and paired transformed follicular lymphoma (tFL) (n=6 samples) 1.73
Identification of Sin3B regulated genes during quiescence 1.73
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells 1.72
Mitotically associated long non-coding RNA, MANCR regulates cell cycle in triple negative breast cancer cells  1.71
Generating Patterned Kidney Organoids for Studying Development and Diseases [bulk RNA-Seq] 1.7
Genome-wide transcriptome analysis of NIPBL iPSC and commited cardiomyoctes 1.7
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT, U0126, CYHX, ActD, EGF, FGF, or IGF and labelled with 4SU 1.69
Time-course expression data from HEK293∆RAF1:ER cells stimulated with 4OHT and labelled with 4SU 1.69
Studying the selectivity of a small molecule Synucleozid on transcriptome 1.69
RNA-seq in neurons derived from iPSCs in controls and patients with schizophrenia and 22q11 del 1.67
Pharmacologic inhibition of STAT5 in AML 1.67
Comprehensive molecular phenotypic effects of the large deletion on chromosome 22q11.2 1.66
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice 1.66
De novo reconstruction of human adipose reveals conserved lncRNAs as regulators of brown adipogenesis 1.65
Identifying the molecular mode of action of itraconazole in colorectal cancer 1.64
Engineered human pluripotent stem cell-derived intestinal tissues with a functional enteric nervous system 1.64
Multiple waves of transcriptome changes during extended hypoxic induction in human pulmonary microvascular endothelial cells 1.59
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence 1.59
Large-Scale Atlas of Mutant IDH1-Dependent Chromatin State Reprogramming, Reversibility, and Persistence [RNA-seq] 1.59
Gene expression profiles in NORAD knockout and PUMILIO overexpressing cells 1.58
Transcriptional profiles of human blood dendritic cell (DC) subsets at steady state 1.58
Identification of grade and origin specific cell populations in serous epithelial ovarian cancer by single cell RNA-seq 1.58
Activation of the p53 transcriptional program sensitizes cancer cells to Cdk7 inhibitors 1.56
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 1.56
Treatment of prostate cancer cells with S-adenosylmethionine leads to genomewide alterations of transcription profiles 1.55
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 1.54
RNA-seq of naive and primed ES cells (NHSM) 1.53
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade 1.51
Identification of altered developmental pathways in human juvenile HD iPSC with 71Q and 109Q using transcriptome profiling 1.51
Transcriptome profiling of 5 human adenocarcinoma cell lines 1.49
Cooperation between TLX1 and the NUP214-ABL1/STAT5 signaling in T-cell acute lymphoblastic leukemia 1.48
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells 1.46
Disease-associated mutation in SRSF2 misregulates splicing by altering RNA binding affinities 1.45
Expression profiling and occupancy after knockdown or over-expression of HFN1A or HNF4G in prostate cancer cells 1.44
Splicing and gene expression changes in human mammary epithelial MCF-10A cells expressing SR or SR-like proteins 1.43
HEXIM1 is induced by DHODH inhibition to suppress melanoma [Gro-Seq] 1.42
HEXIM1 is induced by DHODH inhibition to suppress melanoma 1.42
Single cell analysis of HSV-1 infection reveals anti-viral and developmental programs are activated in distinct sub-populations with opposite outcomes 1.42
Expression profiles of the four human major ectodermal lineages 1.4
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer [RNA-Seq] 1.39
Systematic Functional Perturbations Uncover a Prognostic Genetic Network Driving Human Breast Cancer 1.39
Gene-Edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development 1.38
SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia [RNA-seq] 1.38
Differential expression of pancreatic cancer PANC1 cells treated with pilocarpine 1.38
Conserved roles for murine mDUX and human DUX4 in activating cleavage stage genes and MERVL/HERVL retrotransposons [RNA-Seq] 1.36
Sequencing of messenger RNAs with N6-methyladenosine modifications in acute myeloid leukemia (AML) with and without forced expression of FTO 1.36
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence 1.36
ATRX is necessary for cellular senescence and represses HRAS to drive cells from quiescence into senescence [RNA-Seq] 1.36
PANCR, the PITX2 adjacent noncoding RNA, is specifically expressed in human left atria and regulates PITX2c expression 1.35
CDK4/6 inhibitor resistance in prostate cancer 1.33
Characterization of human ILC2 subsets 1.32
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 1.31
Parvovirus B19 NS1 protein induces cell cycle arrest at G2 phase 1.3
Epigenome regulation during epidermal lineage commitment [RNA-seq] 1.29
Transcriptomic analysis to underly the heterogeneity between 4 cellular models derived from patients diagnosed with pediatric high-grade gliomas under controlled atmosphere (modulation of oxygen level). 1.28
quanTIseq: quantifying immune contexture of human tumors 1.28
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 1.28
mRNAseq of Huntington's disease and control patient iPSC-derived neural cells 1.27
Transcriptomic and Epigenomic analysis of Huntington's disease and control patient iPSC-derived neural cells 1.27
Image based identification and targeting of cancer stem cells in pancreatic adenocarcinoma (PDAC) 1.27
Simultaneous detection and relative quantification of coding and non-coding RNA using a single sequencing reaction 1.27
Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer 1.26
Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes 1.26
SMUG1 promotes telomere maintenance through telomerase RNA end-processing 1.26
The effect of Abl kinases on non-small cell carcinoma global transcriptome 1.24
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 1.24
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 1.23
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 1.23
Next-generation sequencing of control and schizophrenia hiPSC derived NPC 1.21
Genome-wide transcriptome profiles in Control and Schizophrenia hiPSC-dervied NPC [RNA-seq] 1.21
RNA-Seq analysis of cSCC cells followed by siRNA-induced gene knockdown of C1s. 1.2
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 1.19
Total RNA sequencing of APC mutant and wt colonic organoids 1.19
Investigate A2M treatment on human prostate cancer xenograft in mice 1.14
Investigate A2M treatment on human prostate cancer and mouse liver 1.14
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma 1.12
INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq] 1.12
RNA sequencing of hiPSC derived neural crest populations from Familial Dysautonomia patients 1.12
The ARID1A tumor suppressor controls global transcription via pausing of RNA Polymerase II 1.12
Oncolytic reactivation of KSHV as a therapeutic approach for primary effusion lymphoma: RNA-sequencing of PEL cell lines during KSHV reactivation 1.08
Identification of Resistance Genes to BRAF Inhibitor in Melanoma by piggyBac Transposon Activation Mutagenesis Screen 1.08
A single-cell transcriptome atlas of the human pancreas 1.07
Single cell RNA sequencing reveals microglia-like cells in cerebrospinal fluid  during virologically suppressed HIV 1.06
Cellular recruitment by podocyte-derived pro-migratory factors in assembly of the human renal filter 1.05
RNA sequencing quantitative analysis of RNA editing levels in ADAR1, ADAR2, AIMP2 overexpression and wild type HEK293 cells 1.04
A Basal Stem Cell Signature Identifies Aggressive Prostate Cancer Phenotypes 1.04
RNA sequencing of MDA-MB231 and U2OS cancer cell lines exposed to the alkylating agent methyl methanesufonate (MMS) and classical chemotherapeutics  1.03
Disruption of GRIN2B impairs differentiation in human neurons 1.01
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice [HCT116_RNA-seq] 1.01
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice 1.01
Electronic cigarettes 1.01
Sequence dependency and regulatory function of dimeric NOTCH1/RBPJ complexes on coding and non-coding transcription in T-lymphoblastic leukemia 1.01
A Stable Transcription Factor Complex Nucleated by Dimeric AML1-ETO Controls Leukaemogenesis 0.99
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 0.99
PNET animal model: new insights (II) 0.97
Expression profiling by high throughput sequencing of tumors derived from human prostate epithelial cells transformed with the oncogenes N-Myc and myrAKT1. 0.97
RNA sequencing reveals levamisole target genes PTPRZ1 and MDK and their links to interferon pathway in human podocytes 0.95
RB tumor suppressor promotes cancer immunity through downregulating PD-L1 expression 0.95
A Phase II Study of Pomalidomide, Daily Low Dose Oral Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Multiple Myeloma 0.95
Distinct Pathological Signatures in Human Cellular Models of Myotonic Dystrophy Subtypes 0.95
Illumina Human Polycystic Liver Disease and Normal Biliary Stem Cell RNAseq 0.93
Human antimicrobial cytotoxic T lymphocytes, defined by NK receptors and antimicrobial proteins, kill intracellular bacteria 0.93
Expression analysis of PC3 cells treated with scramble AON or AON directed against MBNL1 0.92
Altered mRNA splicing by mutant p53 activates oncogenic RAS in pancreatic cancer 0.92
The mithralog EC-7072 is highly cytotoxic to chronic lymphocytic leukemia cells by targeting the B-cell receptor signaling pathway 0.91
CUREfast: Accelerating research with families 0.91
iPSC derived motor neuron cultures from C9ORF72 carriers 0.91
Differential responses of human fetal brain neural stem cells to Zika virus infection 0.91
Prospective Isolation and Comparison of Human Germinal Matrix and Glioblastoma EGFR+ Populations with Stem Cell Properties 0.89
ZMYND8 reads the dual histone mark H3K4me1-H3K14ac to antagonize the expression of metastasis-linked genes 0.88
MicroRNA-28 replacement for non-Hodgkin lymphoma therapy 0.87
RNA-Seq analysis of proliferating 4N and 2N RPE1 cells derived from single cell clones following inhibition of Aurora B to induce polyploidization [tpo10] 0.85
HLA peptides derived from tumor antigens induced by inhibition of DNA methylation for development of drug-facilitated immunotherapy 0.83
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 0.8
DRB/GRO-Seq -/+ UV 0.8
Generation of Patient-Matched Malignant and Normal Primary Cell Cultures from Clear Cell Renal Cell Carcinoma Patients 0.79
TrapSeq: An RNA Sequencing-based pipeline for the identification of genetrap insertions in mammalian cells 0.77
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG [RNA-seq] 0.76
Re-programing chromatin with a bifunctional LSD1/HDAC inhibitor induces therapeutic differentiation in DIPG 0.76
Cerebral Organoids Recapitulate Epigenomic Signatures of the Human Fetal Brain 0.76
RNA-sequencing of Wnt-dependent and Wnt-independent of Glioblastoma stem cell cultures 0.76
Endometrial transcriptome and PGR cistrome in cycling fertile women [RNA-seq] 0.75
Endometrial transcriptome and PGR cistrome in cycling fertile women 0.75
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 0.74
A Primate lncRNA Mediates Notch Signaling During Neuronal Development by Sequestering miRNA [SHSY5Y cells] 0.74
Campylobacter concisus pathotypes induce distinct global responses in intestinal epithelial cells [UNSWCD] 0.72
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships 0.7
RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships (RNA-seq) 0.7
RNA-seq analysis of YFV-17D specific and total naive CD8 T cells in humans 0.68
RNA deep sequencing to compare genome-wide differences between PRMT5/knockdown and control AML cells 0.67
Alternative classification of glioblastoma based on BUB1B-inhibition sensitivity 0.67
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition [RNA-Seq] 0.66
The ALK downregulated target gene HBP1 and repressor of MYCN activity as synergistic target for combined PI3K/HDAC inhibition 0.66
Patient Derived Xenograft for Delivery of Precision Medicine in Castrate Resistant Prostate Cancer 0.66
Mutated H3 Histones Drive Human Pre-Leukemic Hematopoietic Stem Cell Expansion And Promote Leukemic Aggressiveness 0.66
Transcriptomic Dynamics during Differentiation Process of Human Pluripotent Cells into Hepatocyte-like Cells 0.63
RNA-seq analysis of PRMT5-regulated genes in irradiated/non-irradiated LNCaP cells 0.62
Expression profiles of long non-coding RNAs located in autoimmune disease-associated regions reveal immune cell type specificity 0.62
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 0.57
Transcriptomes of iPSC-derived and post-mortum Hypothalamus Neurons from obese and control donors 0.56
Global gene expression profiles of cardiac progenitors differentiated from human pluripotent stem cells in 3D culture under simulated microgravity 0.55
Long Non-coding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity 0.54
Osmostress induced changes of chromatin architecture and transcription in mammalian cells 0.54
Osmostress induced changes of chromatin architecture and transcription in mammalian cells [RNA-Seq, HiC] 0.54
microRNAs with an AAGUGC seed motif constitute an integral part of a signaling network driving NSCLC cell proliferation 0.53
Changes in human endometrial gland transcriptome over the window of implantation 0.53
Profiling gene expression changes in primary ovarian tumors compared to matched normal fallopian tubes 0.52
Transcriptome of human ILC2s; primary vs IL-1b-primed 0.52
TOP2B disturbed the quality of human oocytes with advanced maternal age 0.51
RNA sequencing of T-ALL (COG study) 0.5
Analyses of T-ALL (COG study) 0.5
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells 0.5
Histone variant H2A.Bbd is associated with active transcription and mRNA processing in human cells [RNA-Seq] 0.5
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 0.49
MHC Transcriptomic landscape at haplotype-specific resolution 0.47
ERK signaling regulates opposing functions of JUN family transcription factors in prostate cancer cell migration 0.46
Potential signaling pathways and gene signatures associated with brain metastases in NSCLC patients 0.45
SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-dependent Tumors 0.44
The expression of genes encoding palmitoylated proteins in axonal and synaptic compartments is affected in CLN1/PPT1 transfected neuronal cells 0.43
Positively selected enhancer elements endow tumor cells with metastatic competence 0.42
Inhibition of the integrin alpha-V beta-3 reverts the paradoxical effect of levothyroxine replacement during bexarotene therapy in cutaneous T-cell lymphoma 0.41
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma 0.41
Direct interaction of MYCN and p53 regulate transcriptional responses in neuroblastoma [RNA-Seq] 0.41
Subtle asymmetry of gene expression in embryonic and foetal human brains 0.4
Gene expression and splicing alterations analyzed by high throughput RNA sequencing of chronic lymphocytic leukemia specimens 0.39
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium [RNA-Seq] 0.38
Role of OSGIN1 in Mediating Smoking-induced Autophagy in the Human Airway Epithelium 0.38
Integrator complex regulates NELF-mediated RNA Polymerase II pause/release and processivity at coding genes. 0.38
Functional significance of the HIV-1 Tat signature amino acid residues 0.38
Smoking Dysregulates the Human Airway Basal Cell Transcriptome at COPD-linked Risk Locus 19q13.2 0.38
Glioblastoma stem cells infected by ZIKA virus 0.38
HIV Reprograms Human Airway Basal Stem/Progenitor Cells to Acquire a Tissue Destructive Phenotype 0.36
FOXO1 is an oncogenic mediator in AML1-ETO leukemia 0.36
RNA-seq analysis in knockdown Jurkat samples for each factor of TAL1 complex 0.36
Oncogenic roles of ARID5B in T-ALL 0.36
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.35
A comprehensive gene expression analysis identifies novel immune signatures in cesarean-born infants 0.34
RNAseq transcriptome analysis of White Blood Cells (WBCs) from individuals with and without trisomy 21 [stranded] 0.33
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis 0.33
The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis [RNA-Seq_Hs] 0.33
A Non-Canonical Nuclear Activity Triggered by Small RNAs and Argonaute Proteins in Human Cells 0.32
Role of BET proteins in YAP/TAZ-dependent transcription [RNA-seq 1] 0.32
The MEF2B Regulatory Network 0.31
The MEF2B Regulatory Network - RNA-seq data 0.31
Sex-specific gene expression differences are evident in human embryonic stem cells and during in vitro differentiation of human placental progenitor cells 0.3
Generation of Brain Region-specific Organoids using a Miniaturized Spinning Bioreactor and Modelling ZIKV Exposure 0.28
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. [RNA-Seq] 0.27
Direct in vivo evidence for B-cell receptor and NF-KB activation in mantle cell lymphoma: role of the lymph node microenvironment and activating mutations. 0.27
RNA-Seq in PWS iPSC-derived neurons 0.27
Sodium butyrate ameliorates aSyn-induced transcription deregulation and DNA damage 0.26
Role of FGFR1 in neuronal devlopment 0.25
RNA sequencing data of whole blood cells of normal glucose tolerant (NGT) and gestational diabetes (GDM) pregnant women 0.25
Hsa-miR-371a-5p and hsa-miR-518a-3p regulated genes in choriocarcinoma cells 0.23
Dissecting cell composition and cell-cell interaction network of normal human heart tissue by single-cell sequencing 0.22
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 0.2
Global Long Terminal Repeat activation participates in establishing the unique gene expression program of classical Hodgkin Lymphoma [RNA-Seq] 0.2
RNAseq of Breast cancer PDX samples 0.2
Transcriptome sequencing of a large human family identifies the impact of rare non-coding variants 0.19
Gene expression in TAL1-driven T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.16
T-cell ALL in response to TAL1-KD, UTX-KD, and GSKJ4 treatment 0.16
Human MAIT cells exit peripheral tissues and re-circulate via lymph in steady state conditions 0.14
YAP and MRTF-A, transcriptional co-activators of RhoA- mediated gene expression, are critical for glioblastoma tumorigenicity 0.14
Efficient and precise editing of endogenous transcripts with SNAP-tagged ADARs 0.13
The lung-enriched p53 mutants V157F and R158L/P regulate a novel transcriptome in lung cancer 0.13
SOX10 Single Transcription Factor Based Fast and Efficient Generation of Oligodendrocytes from Human Pluripotent Stem Cells 0.12
Transcription factors and stress response gene alterations in human keratinocytes following Solar Simulated Ultra Violet Radiation 0.11
YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction. 0.11
YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction [RNA-seq] 0.11
RNASeq of Healthy Human Skin Tregs and CD4 Teffs versus Psoriatic Human Skin Tregs and CD4 Teffs 0.11
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex 0.1
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex (Gro-seq) 0.1
Novel SF3B1 Deletion Mutations Result in Aberrant RNA Splicing in CLL Patients 0.1
The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression [ELL2 rescue] 0.1
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 0.1
Single cell transcriptomics analysis of induced pluripotent stem cell-derived cortical neurons reveals frequent dual layer identity 0.09
Characterizing the Chemoresistant Ovarian Cancer Population using the Heterogeneous PDX 0.09
Gene expression changes due to PARP knockdown in human cells 0.08
Hyper-excitability of Neurons generated from Patients with Bipolar Disorder 0.06
The transcriptome of human endometrial mesenchymal stem cells under TGFβR inhibition reveals improved potential for cell-based therapies 0.06
Reduced CYFIP1 in human neural progenitors as 15q11.2 deletion model: donor specific dysregulation of schizophrenia/epilepsy genes 0.05
Organelle-based therapy for immune mediated disease: mitochondrial transfer elicits Tregs reprogramming 0.05
HSB-2 cells stably expressing LDB1 or mutant LDB1 proteins 0.05
Low-dose decitabine priming endows CAR T cells with enhanced and persistent anti-tumor potential by epigenetic reprogramming 0.03
Kinetics of cytokine receptor trafficking determine signaling and functional selectivity 0.02
Concomitant BCORL1 and BRAF mutations in vemurafenib-resistant melanoma cells 0.01


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