Gene Query: ZNRF1

Dataset Description Geneva Score
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance (RNA-Seq) 34.85
MicroRNA-mediated suppression of the TGF-β pathway confers transmissible and reversible CDK4/6 inhibitor resistance 34.85
Evolved Labels of Placental Invasion in Human and Bovine Endometrial Stroma 29.78
Genome wide expression change in LCC2 and MCF-7 cells 26.69
Analysis and expansion of the eosinophilic esophagitis transcriptome by RNA sequencing 24.36
RNA-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 22.43
RNA-Seq and ATAC-Seq in SMARCD2 k/d NB4 cells with/without ATRA differentiation 22.43
IL-1β induces the rapid secretion of the antimicrobial protein IL-26 from Th17 cells 21.71
Targeted inhibition of STAT/TET1 axis as a potent therapeutic strategy for acute myeloid leukemia 20.95
Single-Cell Genotyping of Transcriptomes 20.48
RNA-seq of Single-Cell Genotyping of Transcriptomes 20.48
Expression levels of genes of NKG2C+ NK cells after in vitro treatment 19.15
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes 18.98
Global Transcriptome Analysis and Enhancer Landscape of Human Primary T Follicular Helper and T Effector Lymphocytes (RNA-Seq) 18.98
PR isoform-specific ER and PR chromatin binding and gene expression observed in-vitro in breast cancer cells. 18.58
Myeloid-derived suppressor cells facilitie invasion and metastasis of papillary thyroid cancer cells by repressing miR-486-3p 17.32
Transcriptional profiling of MCF7 cells treated with H3B05942, E2, or standard of care compounds 16.6
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development [BM low-input mRNA-seq] 16.45
Salmonella activation of STAT3 signaling by SarA effector promotes intracellular replication and production of IL-10 15.79
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor [RNA-seq] 15.65
Development of a selective CDK9 degrader from a multi-targeted CDK inhibitor 15.65
Interphase condensins regulate ligand-depedent enhancer activation (GRO-seq) 14.75
Interphase condensins regulate ligand-depedent enhancer activation 14.75
Gene expression profiles of primary human NK cells before and after expansion on CSTX002 feeder cells, with and without IL-21 stimulation 14.46
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (3' RNA) 14.23
The E3 ubiquitin ligase HectD1 suppresses EMT and metastasis by targeting the +TIP protein ACF7 for degradation 14.09
Whole-Transcriptome Profiling of Canine and Human in Vitro Models Exposed to a G-Quadruplex Binding Small Molecule 13.86
TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation 13.82
RNA-seq in acute myeloid leukemia (AML) cells with and without knockdown of METTL14 13.78
Transcriptomic profile of T cell acute lymphoblastic leukemia (T-ALL) cell from patients in CHCQMU 13.69
RNA-seq analysis of the role of HBO1 (KAT7/MYST2) in the ovarian cancer cell line UWB1.289. 13.4
NR2F2 study 12.23
Estrogen response in breast cancer cell line MCF-7 is dependent on NR2F2 [RNA-seq] 12.23
In vivo genome editing restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers 12.14
Epigenetic reprogramming at estrogen-receptor binding sites alters the 3D chromatin landscape in endocrine resistant breast cancer [RNA-seq] 12.05
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine resistant breast cancer 12.05
RNA-Seq analysis of human Tr1, Tregs and IL10neg cells 11.76
ZRANB2 and SYF2 mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin 11.7
Three-dimensional Oxabicycloheptene sulfonate targets the homologous recombination and repair programs through estrogen receptor α antagonism 11.02
RNA-seq of H1299 cells in which either PRKCI or SOX2 was silenced by validated lentiviral shRNA constructs 10.91
Next Generation Sequencing Facilitates Quantitative Analysis of miR-29b-1 and miR-29a targets in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells 10.8
The effect of REST and its alternatively spliced transcript, REST-003, on breast cancer invasiveness 10.69
Genome Wide Chromatin Mapping of accessibility (ATAC-seq) and H3K27ac histone modifications in CD56bright and CD56dim natural killer cells 10.58
Dynamic gene expression in T-ALL following treatment and release of gamma-secretase inhibition [GRO-Seq] 10.56
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone [IMR90_MCF7_RNA-Seq] 10.25
Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone 10.25
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing 10.08
Transcriptome analysis of Jurkat T-ALL clones from control and CBAP-knockdown/knockout sets 10.03
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer [RNA-seq] 9.9
A non-canonical role of YAP/TEAD is required for activation of estrogen-regulated enhancers in breast cancer 9.9
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia [RNA-seq] 9.9
Lymphocyte-specific chromatin accessibility pre-determines glucocorticoid resistance in acute lymphoblastic leukemia 9.9
The long non-coding RNA MALAT1 contributes to the pathogenesis of multiple sclerosis through alternative splicing and backsplicing regulation 9.43
MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia. 9.27
RNA-seq of YB5 and MCF7 treated with different doses of decitabine 9.22
24hr CA treatment vs. DMSO in HCT116 cells (from 'Identification of CDK8 and CDK19 substrates in human cells using cortistatin A and quantitative phosphoproteomics') 9.15
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [d7+d14] 9.06
Genome-wide expression change by SHARPIN knockdown in MCF-7 cells 8.99
Comparative genome-wide analysis of human BM IL3Rα-high precursors show a more MΦ-, DC- and OC committed gene expression profile, as compared to IL3Rα-low precursors 8.91
Comparative total RNA and mRNA sequencing and systems analysis reveals nascent transcriptional response to early HIV-1 infection in a CD4+ T cell line 8.88
Landscape of human mast cell chromatin: a rich resource for identification of novel mediators and genetic drivers of allergic and inflammatory diseases 8.73
Transcriptomic profiling of human CD34+ derived mast cells [RNA-Seq] 8.73
BET bromodomain proteins function as master transcription elongation factors independent of CDK9 recruitment [NET-seq] 8.66
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer 8.63
The splicing factor RBM25 controls MYC activity in Acute Myeloid Leukemia 8.61
Gene expression analysis of ER+ and ER- breast cancer cell lines with acquired resistance to palbociclib 8.43
Human Treg IL-12 stimulation 8.3
Bone marrow derived human B cells [normal proB] 8.09
Identification of global regulators of T-helper cell lineage specification 8.07
Identification of global regulators of T-helper cell lineage specification (RNA-Seq) 8.07
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells [RNA-Seq] 8.0
CTCF and CohesinSA-1 Mark Active Promoters and Boundaries of Repressive Chromatin Domains in Primary Human Erythroid Cells 8.0
The role of TFEB in retinoid induced differentiation of NB4 APL leukemic cells (shTFEB) 8.0
Long Non-coding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity 7.98
Silencing p300 in MCF7 cells to study expression and alternative splicing 7.94
Interaction between mitoNEET and NAF-1 in cancer cells 7.89
Microenvironmental-derived Regulation of HIF-Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme 7.86
Gene expression in control and DOCK8 CRISPR KHYG1 NK cells 7.81
Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis [ZNF787] 7.79
Expression profiling of MCF-7 cells with treatment of TCDD 7.77
Expression profiling of MCF-7 cells with 10nM treatment of TCDD 7.77
Induction of human SST and PV neurons by expressing a single transcription factor LHX6 7.72
Modulation of Indoleamine 2, 3-dioxygenase 1 Expression by Activated Human T cells in Breast Cancer Cells is Controlled by DNA Promoter Methylation 7.64
Parkinson’s Disease Genetic Risk in a Midbrain Neuronal Cell Line 7.58
Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection 7.55
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer 7.43
Transcriptional Targeting Of Oncogene Addiction In Medullary Thyroid Cancer [RNA-Seq] 7.43
Transcriptome-wide identification of CELF2 functional targets in T cells 7.43
Energy Metabolism during Anchorage-Independence 7.4
snRNAs as regulators of alternative splicing 7.38
Single Cell Analysis Reveals Unexpected Transcriptional Heterogeneity of Neural Progenitors in the Developing Human Cortex 7.3
Mutant p53 controls tumor metabolism and metastasis by regulating PGC-1α 7.16
RNA-seq data from human lymphoma cell lines 7.07
ChIP-seq and RNA-seq from human lymphoma cell lines 7.07
BET bromodomain inhibitor iBET151 impedes human ILC2 activation and prevents experimental allergic lung inflammation 7.06
Knockdown of FOXP1 promotes the development of lung adenocarcinoma 7.06
Gene expression profile of regenerated CD8αα T cells and CD8αβ T cells from LMP2 T-iPSCs 7.06
Expression profiling of ILC transitional populations and Aiolos accessability and H3K27ac histone modifications in transfected MNK3 cells 6.92
RNA-Seq from human ILC transitional populations 6.92
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits 6.84
Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits [mRNA-Seq] 6.84
Distinct and shared functions of ALS-associated TDP-43, FUS, and TAF15 revealed by comprehensive multi-system integrative analyses [RNA-Seq_human] 6.79
Luminal lncRNAs Regulation by ERα-controlled Enhancers in a Ligand-independent Manner in Breast Cancer Cells 6.78
RNA-Seq of human induced pluripotent stem cell-derived cardiomyocytes from a cardiomyopathy patient and familial control 6.78
Tumors with TSC mutations are sensitive to CDK7 inhibition through NRF2 and glutathione depletion 6.76
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth [RNA-Seq] 6.7
ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth 6.7
Luminal subtype-specific circRNAs in breast cancer cells by a novel tool for external data analysis. 6.67
Integration of kinase and calcium signaling at the level of chromatin underlines inducible gene activation in T cells 6.61
Epigenetic Therapy Increases Therapeutic Efficacy in Myeloproliferative Neoplasms Through Inhibition of Aberrant Inflammatory Signaling 6.56
Transcriptomic analysis of healthy donor and Sickle Cell Disease (SCD) hematopoietic stem/progenitor cells 6.54
Gene expression profile in breast cancer cell lines using RNA sequencing 6.45
Epigenomic landscape during organ formation in human early embryos 6.37
Antibodies That Convert Bone Marrow Into Trafficking Microglia-Like Cells Reduce Brain Amyloid 6.35
Identification of the O-GlcNAc-regulated alternative splicing events by performing RNA sequencing on HeLa cells with altered O-GlcNAc level. 6.34
Integrin signaling regulates YAP/TAZ to control skin homeostasis 6.34
Human Pancreatic Islets Expressing HNF1A Variant Have Defective β cell Transcriptional Regulatory Networks 6.3
Perivascular signals alter global genomic profile of glioblastoma and response to temozolomide in a gelatin hydrogel 6.29
Activating PAX Gene Family Paralogs to Complement PAX5 Leukemia Driver Mutations 6.28
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq B-ALL) 6.28
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq] 6.26
RNA seq data of Hep3B-control, Hep3B-sertraline, Hep3B-XL413, Hep3B-XL413-sertraline, Huh7-control, Huh7-sertraline, Huh7-XL413, Huh7-XL413-sertraline cells 6.12
Temporal dynamic reorganization of 3D chromatin in hormone-induced breast cancer and endocrine resistance 6.04
Endothelial Cells Control Pancreatic Cell Fate at Defined Stages through EGFL7 Signaling 6.03
Charaterization of genetic alterations and gene expression signatures found in BCR-ABL inhibitor-resistant KCL-22 subpopulations and single clones 6.03
Role of miR-146a in neural stem cell differentiation and neural lineage determination: relevance for neurodevelopmental disorders 6.02
Cancerous inhibitor of PP2A (CIP2A) Constrains Th17 Differentiation by Modulating STAT3 Signaling 5.98
Total RNA-seq in ALL-SIL upon JQ1 inhibition 5.96
CDK12 catalytic activity is rate-limiting for RNAPII processivity on core DNA replication genes and G1/S progression (nuclear RNA) 5.95
Transcriptomic analysis of human tonsillar TFH subsets 5.95
TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells 5.89
TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells [RNA-seq] 5.89
Hijacking of stress response machinery by oncogenes in acute leukaemia 5.87
Hijacking of stress response machinery by oncogenes in acute leukaemia [RNA-seq] 5.87
RNA-Seq analysis of breast cancer cells after shikonin treatment 5.86
Compensatory Csf2-driven macrophage activation blunts long-term efficacy of therapeutic Csf1r inhibition in breast-to-brain metastasis 5.82
Comparative gene expression profiling of MHH-CALL4 cells subject to pharmacological JAK2 inhibitor treatment (ruxolitinib or CHZ868) or shRNA-mediated JAK2 depletion in vitro 5.77
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias 5.77
The DNM3OS lncRNA is a reservoir of fibromiRs with major functions in fibroblast response to TGF-beta and fibrogenesis 5.75
RNA-Seq analysis of human lung fibroblasts exposed to TGF-β 5.75
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells [RNA-seq] 5.74
Distinct Roles of BET Family Members in ERα Enhancer Function and Gene Regulation in Breast Cancer Cells 5.74
Disrupted prenatal RNA processing and myogenesis in congenital myotonic dystrophy 5.73
Transcriptome splicing analysis in K562 cells expressing rare and private spliceosomal mutations 5.7
MLL-AF4 binds directly to a BCL-2 specific enhancer and impacts H3K27 acetylation 5.67
Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis . 5.67
a-synuclein accumulation in an iPSC derived model of early onset sporadic Parkinson’s Disease reveals novel drug targets 5.66
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells 5.61
DNA methylation state is associated with the formation of loops and links in hematopoietic stem cells [RNA-seq] 5.61
Evolution of a transcriptional regulator from a transmembrane nucleoporin 5.55
RNA-seq in HepG2 and IMR90 cells 5.55
Role of SUMOylation in differential ERα transcriptional repression by SERMs and pure antiestrogens in breast cancer cells 5.54
Integrated analysis of MLL-AF9 AML patients and model leukemias highlights RET and other novel therapeutic targets (RNA-seq AML development) 5.53
Transcriptome profile of ATP7B KO cells and WT cells treated with Copper (Cu) to study Autophagy as a pro-survival mechanism in Wilson disease 5.49
Patient iPSC-Derived Neurons for Disease Modeling of Frontotemporal Dementia with Mutation in CHMP2B 5.37
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice 5.34
Cistromic re-programming by truncating GATA3 mutations promotes mesenchymal transformation in vitro, but not mammary tumour formation in mice [RNA-seq] 5.34
Single-cell transcriptomic analysis of tissue resident memory T cells in human lung cancer [ 10x genomics] 5.31
TCR and inflammatory signals tune human MAIT cells to exert specific tissue repair and effector functions 5.27
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia 5.26
Effect of BCL11B overexpression on transcriptome of T-cell acute lymphoblastic leukemia (T-ALL) cells 5.24
Specific inhibition of DPY30 activity by peptides suppresses blood cancer cell growth 5.22
Characterization of human ILC2 subsets 5.14
RNA-sequencing of mRNAs from control and CAP-D3 deficient Salmonella infected HT-29 cells 5.14
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing Mbnl1 [RNA-seq & Ribo-seq] 5.14
The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1 5.14
Complete deconvolution of cellular mixtures based on linearity of transcriptional signatures 5.14
UPA-Seq: Prediction of functional lncRNAs using the sensitivities to UV-crosslinking 5.13
An integrative analysis of non-coding regulatory DNA variations associated with autism 5.11
Transcriptomic profiling of human peripheral blood-derived mast cells 5.09
Genome-wide analyses of chromatin state in human mast cells reveal molecular drivers and mediators of allergic and inflammatory diseases 5.09
Multiple mechanisms disrupt let-7 miRNA biogenesis and function in neuroblastoma [longRNA] 5.06
RNA-seq analysis of BAP1-depleted uveal melanoma cells 5.06
Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease 5.06
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 [RNA-seq] 5.05
C/EBPα overexpression overrides epigenetic reprogramming by RUNX1-ETO and RUNX1-EVI1 5.05
Genetic disruption of COX-1 inhibits multiple oncogenic pathways 5.05
Combinatorial Reprogramming of Estrogen Signaling by the Nuclear Receptor Family 3C 5.04
A faithful in vivo model of human MLL-AF4 proB acute lymphoblastic leukemia 5.04
RNA-Seq Analysis of Anacardic Acid Treated MCF7 and MDA-MB-231 Breast Cancer Cell Lines 4.99
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion 4.99
Long non-coding RNA RP11-19E11.1 is an E2F1 target required for tumor cell proliferation and survival in basal breast cancer 4.95
Expression profile of Lo19S state cells in the presence and absence of bortezomib treatment 4.93
Analysis of Th17 gene signature in the presence of CD28 costimulation in human CD4 naïve T cells 4.89
mRNA-seq from Nutlin-3a, doxorubicin, and DMSO treated HCT116 p21-/- cells 4.88
Next Generation Sequencing for Quantitative Analysis of transcriptome of follicular compared to non-follicular CD8 T cells from HIV+ Lymph nodes 4.87
Examining serotonergic neuron differentiation from human iPSCs 4.84
Specific modulation of HIV RNA splicing and upregulation of anti-inflammatory miR-124 by the new drug candidate ABX464 4.84
TMED9-gated CNIH4 and TGFa signaling promotes pro-metastatic states in human primary colon cancer cells 4.82
A systematic analysis of nuclear heat-shock protein 90 identifies a metazoan-specific regulatory module 4.81
RNA-seq data corresponding to: AZD4573 is a highly selective CDK9 inhibitor that suppresses Mcl-1 and induces apoptosis in hematological cancer cells 4.81
Differential Gene Expression between MCF10A and MCF7 cells 4.8
RNA-sequencing WT vs SOCS3 knockout Glioblastoma stem-cells 4.78
RNA expression profiling of human mPB or CB-derived CD34+ cells treated with UM171 at different doses 4.74
Identification of PRMT5-dependent genes in ESA+CD24lowCD44+ MCF7 cells 4.71
The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia 4.69
Transcriptomic analysis of the effect of trastuzumab in human iPSC-CMs 4.65
RNA-seq analysis of SKMEL28 melanoma cells following DIRC3 and IGFBP5 ASO knockdown 4.63
The transcriptomic landscape of MAIT cell development in the thymus (NN41 RNAseq data set) 4.58
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming 4.52
Neurofibromin is an Estrogen Receptor alpha Transcriptional Co-repressor in Breast cancer 4.5
Messenger RNA expression after silencing or inhibition of MEN1in MCF-7 breast cancer cells 4.49
Urinary sediment transcriptomic and longitudinal data to investigate renal function decline in type 1 diabetes 4.49
RNA-seq analysis of AML cells in response to ASLAN003 4.44
Rational targeting of cooperating layers of the epigenome yields enhanced therapeutic efficacy against AML 4.43
A high-throughput screening strategy identifies regulators of alternative splicing via interaction with RNA G-quadruplexes 4.41
RNA-seq transcriptional profiling in human primary fetal and adult CD34+ hematopoietic stem/progenitor cells (HSPCs) erythroid progenitor cells (ProEs) 4.4
RNAseq of cell lines with knocked in ESR1 mutations 4.38
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 4.37
Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer. 4.37
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference [RNA-Seq] 4.35
Inhibition of DNA methylation promotes breast tumor sensitivity to netrin-1 interference 4.35
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq 4.34
Gene expression analysis of airway epithelial cells exposed to flagellin via RNA-seq and microarray 4.34
Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration 4.32
DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation 4.32
RNA-Sequencing experiment for effects of PKF115-584 treatment on four T-ALL cell lines (RPMI8402, HPB-ALL, Jurkat, CCRF-CEM). 4.32
Genome wide expression change by RNF168 knocking down in MCF-7 cells 4.3
A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity 4.3
Global gene expression profile of dasatinib-resistant RCH-ACV cells 4.29
The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin Remodeling Complexes 4.28
Brain organoids reproducibly generate the cellular diversity of the human cerebral cortex 4.27
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation 4.25
Bromodomain protein BRD4 is required for estrogen receptor-dependent transcription and enhancer activation [RNA-Seq] 4.25
Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid 4.22
Integrative Genomic and Transcriptomic Analysis Identified Candidate Genes Implicated in the Pathogenesis of Hepatosplenic T-cell Lymphoma 4.2
Hepatosplenic T cell lymphoma 4.2
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo 4.17
RNA sequencing Facilitates Quantitative Analysis of luminal breast cancer cells and basal breast cancer cells Transcriptomes 4.16
MYOD Remodeling of the Genome Architecture during Myogenic Conversion of Somatic Cells 4.15
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis 4.14
MKL1 augments megakaryocyte maturation by enhancing the SRF regulatory axis [RNA-seq] 4.14
Time series single-cell transcriptomic analysis of AEC2 directed differentiation 4.11
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug. 4.1
Transcriptome analysis reveals malignant and hypoxic signature of glioblastoma 4.1
Profiling of protrusion-enriched RNAs from human breast cancer cell line MDA-MB-231 4.09
ERK potentiates transactivation and oncogenic function of ERG by phosphorylation induced dissociation of PRC2 complex 4.08
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L 4.02
Effect of OVO-like 1 knockdown on global transcript expression in differentiated BeWo trophoblast cells 4.01
CHCHD10 gene KO effect in iPSC drived motor neurons 4.01
Gene expression in GBM with Cav3.2 inhibition 3.98
Patient-derived luminal breast cancer xenografts with progestins 3.94
RNAseq analysis of patient-derived luminal breast cancer xenografts treated with progestins 3.94
Defining the Transcriptional Landscape during Cytomegalovirus Latency with Single-Cell RNA Sequencing 3.93
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 3.92
Stretch-Enhancers Delineate Disease-Associated Regulatory Nodes in T Cells 3.91
RNA-seq analysis of umbilical cord blood cells upon knockdown of NAP1L3 3.9
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques 3.9
ChIP-seq of ER and RUNX2 in MCF7 breast cancer cell lines 3.89
Transcriptome analysis of genetically matched human induced pluripotent stem cells disomic or trisomic for chromosome 21 3.88
Peptidomimetic blockade of MYB in acute myeloid leukemia 3.86
Peptidomimetic blockade of MYB in acute myeloid leukemia [RNA-seq] 3.86
Functional Importance of eRNAs for Estrogen-dependent Gene Transcriptional Activation 3.85
Global epigenomic reconfiguration during mammalian brain development 3.83
Suppression of NAF-1 in Breast Cancer Cells Reduces their Tumorigenicity by Interfering with Cellular Iron Distribution and Metabolism and Ensuing ROS Formation and Apoptosis 3.79
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex 3.79
Enhancer Activation Requires Trans-Recruitment of a Mega Transcription Factor Complex (Gro-seq) 3.79
Targeting the androgen receptor N-terminus via the cochaperone Bag-1L [RNA-seq C-terminal mutant] 3.76
3.71
HuR controls apoptosis and activation response without effects on cytokine 3′ UTRs 3.71
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation [RNA-Seq] 3.69
IFN-g Regulates mTORC1, Cellular Metabolism and mRNA Translation to Potentiate Inflammatory Macrophage Activation 3.69
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner 3.69
IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner [Huh-7] 3.69
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and PVT1 Knockdown by CRISPRi in MDA-MB-231 human breast cancer cell line 3.69
Promoter of lncRNA gene *PVT1* is a tumor suppressor DNA element 3.69
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer 3.68
The Chromatin-Looping Factor ZNF143 Engages at Looping Promoters to Favor the Estrogen Response in Breast Cancer (RNA-seq) 3.68
BCL11B 3.66
TGFβ-induced fibroblast activation requires persistent and targeted HDAC-mediated gene repression 3.66
Restoration of Progranulin Expression Rescues Cortical Neuron Generation in Induced Pluripotent Stem Cell Model of Frontotemporal Dementia 3.66
Disruption of Na+/H+ exchanger regulatory factor 2 scaffold suppresses colon cancer proliferation 3.63
Global Gene Expression analysis of CUTLL1 cell lines after treatment with Perhexiline 3.62
Impact of DNA MMR activity on antiviral gene expression in H441 cells infected with influenza A virus 3.62
RNA-Sequencing of HUVEC treated with Tie2 activating antibody 3.6
Estrogen deprivation triggers and immunosuppressive phenotype in breast cancer cells 3.59
Serotonin-induced hyperactivity in SSRI-resistant major depressive disorder patient-derived neurons 3.59
Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with Eralpha 3.58
MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia [inhibitor MRT199665] 3.57
Overexpression of ERG in cord blood progenitors promotes expansion and recapitulates molecular signatures of high ERG leukemias 3.51
APT1 regulates the asymmetric partitioning of Notch and Wnt signaling during cell division 3.5
Transcriptome wide analysis of translation efficiency in MCF7 cells using polysome profiling with and without eIF4A inhibition by hippuristanol treatment 3.49
Insulin receptor associates with promoters genome-wide and regulates gene expression [RNA-seq 2] 3.49
Regulation of hypoxia-inducible factor activity by ZMYND8 3.43
Transcriptome analysis of PC9 cells with gefitinib or/and hypoxia treatment and comparison with gefitinib resistant PC9 cells and ALDH positive PC9 cells 3.41
RNA Sequencing Facilitates Quantitative Analysis of Transcriptomes of H1 and H1 after SNAI1 deletion at Day2 after human early hematopoietic differentiation . 3.41
Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing 3.39
RNA-seq analysis of human KMT2A rearranged MV4;11 AML cell line treated with DOT1L and/or EZH2 inhibitor 3.36
Mllt3 Governs Self-Renewal And Engraftment Of Human Hematopoietic Stem Cells 3.34
RNA-seq of MLLT3-overexpressing cultued HSPC, compared to non-overexpressing and uncutured FL-HSPC [RNAseq_MLLT3_OE] 3.34
RNA-Seq characterization of human H1-derived NPC differentiation timecourse 3.31
Neonatal and adult human testis defined at the single-cell level 3.31
Active translatome profiling with RiboLace in MCF7 cells 3.26
Genetic disarray follows mutant KLF1-E325K expression in a congenital dyserythropoietic anemia patient 3.21
Regulation of cellular heterogeneity and rates of symmetric and asymmetric divisions in triple-negative breast cancer 3.21
Consequences of Ribosomal Protein Haploinsufficiency in Human Hematopoiesis 3.17
Determination of a comprehensive alternative splicing regulatory network and the combinatorial regulation by key factors during Epithelial-to-Mesenchymal Transition [ESRP KD] 3.15
CHCHD2 gene KO effect in iPSC drived motor neurons 3.13
A single cell reference map for human blood and tissue T cell activation 3.12
CXCR4 is a host factor that regulates Plasmodium development in hepatocytes 3.12
Regulators of cellular heterogeneity in basal-like breast cancer influence symmetric versus asymmetric division rates (shRNA targeting) 3.12
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer 3.12
Characterizing the contrasting roles of JMJD3 and UTX histone demethylases in T cell acute lymphoblastic leukemia [GSKJ4_RNA-seq] 3.11
Nuclear receptor RORγ is a targetable master regulator of cholesterol in a subtype of breast cancer [RNA-Seq] 3.05
Differential Protein Occupancy Profiling of the mRNA Transcriptome 3.04
HMGA1 and FOXM1 synergistically regulate a common gene network modulating angiogenesis in breast cancer 2.96
Expression and functions of long noncoding RNAs during human T helper cell differentiation 2.94
Hyperactive mTOR and MNK1 phosphorylation of eIF4E confer tamoxifen resistance and estrogen independence through selective mRNA translation reprogramming 2.89
Transciptomic profiling of human fetal lung samples 2.88
Gene expression and genome-wide location analysis of breast cancer cell-lines 2.85
Gene expression analysis of breast cancer cell-lines 2.85
Genome-wide transcriptional profiling of YAP target genes in human endothelial cells 2.85
FOXP3 protects conventional human T cells from premature restimulation-induced cell death 2.78
Loss of the Chr16p11.2 candidate gene QPRT leads to aberrant neuronal differentiation 2.78
GRHL2 is a key lineage determining factor which collaborates with FOXA1 to establish a targetable collateral pathway in the setting of endocrine therapy-resistant breast cancer (RNA-Seq data set 1) 2.76
Effect of drugs on transcriptomic profiles 2.74
In Vitro and In Vivo Modulation of Alternative Splicing by the Biguanide Metformin. 2.73
Transcriptional profiling of JEG3 cells with HLA-G ablation via deletion of Enhancer L 2.69
Highly-motile versus unsorted MDA-MB-231 breast cancer cells 2.69
Chemical Modulation of Glycolysis Regulates the KEAP1-NRF2 Pathway Through a Metabolite-Induced Posttranslational Modification 2.68
Nudt3 is a mRNA Decapping Enzyme That Modulates Cell Migration 2.62
Inactivation of CFTR by CRISPR/Cas9 alters transcriptional regulation of inflammatory pathways and other networks 2.6
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros 2.6
A CLK3-HMGA2 alternative splicing axis impacts human hematopoietic stem cell molecular identity throughout development (HPC-5F RNAseq) 2.56
Identification of epigenetic interactions between miRNA and DNA methylation associated with polycystic ovarian syndrome 2.55
Transcriptome Profiling Reveals the key genes and pathways involved in polycystic ovary syndrome [RNA-seq] 2.55
HMGA2 Promotes Long-Term Engraftment and Myelo-Erythroid Differentiation of Human Hematopoietic Stem and Progenitor Cells 2.53
Transcriptome analysis of Riociguat and Vehicle control treatment in human hematopoietic stem and progenitor cells 2.51
Next Generation Sequencing Facilitates Quantitative Analysis of UVB(20mJ/cm2 and 40mJ/cm2) exposed and untreated HaCaT keratinocytes Transcriptomes 2.5
ARID1A and ARID1B loss in HCT116 and TOV21G cells 2.5
RNA-seq of healthy CD34+ HSPCs after co-culture with myelodyplastic syndrome patient-derived mesenchymal stromal cells 2.49
Transcriptome analyses of iPSC-derived neural stem/progenitor cells and cerebral organoids from monozygotic twins discordant for schizoaffective bipolar disorder 2.48
Discovering human diabetes-risk gene function with genetics and physiological assays 2.46
MAIT cell RNA sequencing 2.45
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes 2.45
Integrative Analysis of Tamoxifen-resistant Cell Line Models Based on Sequencing Genomes, Transcriptomes and Epigenomes [seq] 2.45
Therapy-induced hypoxia contributes to AML drug-resistance through BMX Kinase upregulation 2.44
Iron response of HepG2 cells 2.43
Recapitulation of Human Neural Microenvironment Signatures in iPSC-Derived NPC 3D Differentiation 2.41
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures 2.4
Repression of stress-induced LINE-1 expression protects cancer cell populations from lethal drug-exposures [RNA-Seq] 2.4
Sequence dependency and regulatory function of dimeric NOTCH1/RBPJ complexes on coding and non-coding transcription in T-lymphoblastic leukemia 2.37
LncRNA-dependent mechanisms of androgen receptor-regulated gene activation programs 2.37
Insulin induced alterations in chromatin acetylation and transcriptome in triple negative breast cancer cells 2.34
A cell cycle-based functional screen to identify lncRNA-based cancer biomarkers 2.33
Transcriptome profiling in primary human skeletal myotubes with MondoA knockdown 2.32
MondoA Links Muscle Lipid Accumulation and Insulin Resistance Driven by Nutrient Overload 2.32
Long non-coding RNA profiling of human lymphoid progenitors reveals transcriptional divergence of B cell and T cell lineages 2.31
Leucegene: AML sequencing (part 6) 2.31
ELAVL2-regulated transcriptional networks in human neurons link atlernative splicing, autism and human neocortical evolution 2.3
Generation and persistence of human tissue-resident memory T cells in lung transplantation 2.29
G9a-Mediated Methylation of ERα Links the PHF20/MOF Histone Acetyltransferase Complex to Hormonal Gene Expression 2.29
RNA profiling Analysis of the Serum Exosomes Derived from Active and Latent M.tuberculosis infectious Patients 2.28
Decoding breast cancer tissue-stroma interactions using species-specific sequencing 2.24
Kinetics of cytokine receptor trafficking determine signaling and functional selectivity 2.23
SHANK2 mutations associated with autism spectrum disorder cause hyperconnectivity of human neurons 2.22
FGF2 regulation of gene expression in stable inducible Neurons 2.22
Research resource: global identification of estrogen receptor β target genes in triple negative breast cancer cells 2.21
Gene expression profiling in follicular lymphoma (FL) samples and paired transformed follicular lymphoma (tFL) (n=6 samples) 2.21
The serine hydroxymethyltransferase-2 (SHMT2) initiates lymphoma development through epigenetic tumor suppressor silencing. 2.21
Gene expression regulated by CSA and CSB in neuroblastoma cell line 2.21
Transcriptional profiling of CD45RO+CD57+CD4+ T cells 2.2
Disruption of GRIN2B impairs differentiation in human neurons 2.17
Human Adult Sorted Live Cell Erythroblasts RNA-Seq. 2.13
Impact of library preparation on downstream analysis and interpretation of RNA-seq data: comparison between Illumina PolyA and NuGEN Ovation protocol 2.07
Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence. 2.06
Identification of novel recurrent ETV6-IGH fusions in primary central nervous system lymphoma using high throughput RNA sequencing 2.02
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process (RNA-seq) 2.0
Cockayne syndrome A and B proteins regulate the transcription arrest upon genotoxic stress through a ubiquitin/proteasome degradation process 2.0
Effect on small molecule RBPJ inhibitor (RIN1) on gene expression in Jurkat cells compared to gamma secretase inhibition and siRNA knockdown of RBPJ 1.98
Transcriptome analysis of the HepG2 cells expressing hepatic transcription factors 1.96
Aberrant splicing in B-cell acute lymphoblastic leukemia [B-ALL] 1.94
RNA-Seq of LRRK2 G2019S Parkinson’s iPSC-derived astrocytes 1.93
Human Treg NaCl stimulation 1.9
Single cell RNA-seq resolves lineage-specific activation dynamics of human blood and tissue T cells 1.87
Mutated H3 Histones Drive Human Pre-Leukemic Hematopoietic Stem Cell Expansion And Promote Leukemic Aggressiveness 1.87
mRNA profiling reveals determinants of trastuzumab efficiency in HER2-positive breast cancer 1.85
miRNAs affected by antagomiR-17 treatment 1.83
single cell RNA-seq from Purkinje cell (ENCSR888LYA) 1.76
Gene expression of thyroid cancer cell lines 1.75
Expression data for KDM1B knockdown in Glioma-Initiating Cells (GICs) 1.71
THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors 1.68
Single-cell Transcriptomics reveals multi-step adaptations to endocrine therapy 1.68
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders 1.67
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders [lnc-Nr2f1 overexpression] 1.67
Gene expression profile of LMSU gastric cancer cell p53 KO and KD 1.66
Tissue-resident memory T cells mediate immune homeostasis in the human pancreas through the PD-1/PD-L1 pathway 1.65
DDX54 regulates transcriptome dynamics during DNA damage response [4SU-seq] 1.65
JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML 1.65
JAK dependent survival of ALK- ALCL 1.63
SILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors 1.62
Genome-wide expression from the esophageal biopsies of subjects with and without eosinophilic esophagitis 1.6
Gene expression changes due to PARP knockdown in human cells 1.58
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection 1.56
Self-organized cerebral organoids with human specific features predict effective drugs to combat Zika virus infection [RNA-seq] 1.56
Single-cell transcriptomics of human oocytes: environment-driven metabolic competition and compensatory mechanisms during oocyte maturation 1.54
Mutational landscape of aggressive natural killer-cell leukemia and drug profiling highlight JAK-STAT signaling as a therapeutic target in NK-cell malignancies 1.53
Distinct Pathological Signatures in Human Cellular Models of Myotonic Dystrophy Subtypes 1.51
H1609088 Human RNA-Sequencing 1.5
Human Embryoid Body Transcriptomes Reveal Maturation Differences Influenced by Size and Formation in Custom Microarrays 1.49
Characterisation of the myeloid differentiation process of human hematopoietic stem cells 1.49
The Hippo pathway kinase LATS1 scaffolds Beclin1 in autophagy regulation in hepatocellular carcinoma 1.48
Total RNA-seq in ALL-SIL upon TLX1 knockdown 1.47
Fusion discovery in breast cancer cell line 1.47
Transcriptome-wide analysis of IL2RA enhancer activation by CRISPRa 1.45
Transcriptomic analysis of human neural progenitor cells differentiation into astrocytes 1.41
Expression Analysis of dic(1;7)(q10;p10) in Myelodysplastic Syndromes (MDS) compared to control cohort and therapy-related Myeloid Neoplasms (t-MN) 1.4
A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS) 1.4
Integrated high-throughput screen to identify novel treatment leads for pediatric acute myeloid leukemia (AML) 1.38
RNA-seq on Enasidenib or DMSO Treated CD71+ Cells from Umbilical Cord Blood (UCB) 1.37
Impact on erythroid progenitor type on erythroid differntiation 1.35
Genome-wide Analysis of Chromatin Interactions in Human Cells 1.29
5hmC and gene expression data in breast cancer cell lines treated with an antioxidant 1.29
Targeting MTHFD2 in Acute Myeloid Leukemia 1.29
Role of FGFR1 in neuronal devlopment 1.28
RNAseq of CCRF-CEM, a T-cell acute lymphoblastic leukemia cell line, after knockdown with 2 control hairpins and 6 hairpins targeting the PRC2 complex. 1.28
Neural cell adhesion molecule 1 (NCAM1; CD56) promotes leukemogenesis and confers drug resistance in acute myeloid leukemia. 1.27
α Cell Function and Gene Expression Are Compromised in Type 1 Diabetes 1.24
Primate-specific gene TMEM14B promotes cortical expansion and folding 1.23
Transcriptomic profiling of sequential tumours from breast cancer patients provides a global view of metastatic expression changes following endocrine therapy 1.19
RNA sequencing of 13 T-cell acute lymphoblastic leukemia patients (5 TCRAD-MYC translocated T-ALL_8TAL1-LMO2 T-ALL) 1.18
MARS Seq data from human cortical organoids 1.17
Dermal endothelial cells of type 2 diabetic patients 1.17
Splicing and gene expression changes in human MDAM-MB231 breast cancer cells with TRA2B knockdown 1.16
MCF-7 as a model for functional analysis of breast cancer risk variants 1.15
Profiling in vivo Bone Lesion (IVBL) and Orthotopic tumors by Next Generation Sequencing 1.14
Transcriptome of Primitive Human Hematopoietic Cells: A New Resource to Find hHSC-Specific Genes 1.13
RNAseq of T-ALL upon long non coding rna purturbation 1.12
The RNA-binding protein RBM47 suppresses metastatic breast cancer progression 1.12
Intrinsic Plasma Cell Differentiation Defects in BENTA Patient B cells 1.12
Single amino acid change underlies distinct roles of H2A.Z subtypes in human syndrome 1.07
Rescue of Fragile X syndrome neurons by DNA methylation editing of the FMR1 gene [RNA-seq] 1.04
Rescue of Fragile X syndrome by DNA methylation editing of the FMR1 1.04
Expression alterations induced by restoration of AXIN1 expression in SNU449 hepatocellular carcinoma cells 0.98
Impeding transcription of expanded microsatellite repeats by deactivated Cas9 0.94
Direct Isolation and Characterization of Human Nephron Progenitors. 0.94
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors 0.92
RNA-seq expression data from FL-HSPCs after HOXA7 knockdown 0.92
Illumina Total RNA-seq in HeLa 0.88
Next Generation Sequencing Quantitative Analysis of Wild Type and AML1-ETO Related Fusion Circular RNA (F-CircAE) Knockdown Kasumi-1 Cells Transcriptomes 0.87
Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements 0.85
Long noncoding RNA signatures induced by TLR7 and type I IFN signaling in activated human plasmacytoid dendritic cells 0.84
Specific molecular signatures underlie response to decitabine in CMML [RNA-seq] 0.81
Specific molecular signatures underlie response to decitabine in CMML 0.81
RNA-seq analysis of breast cancer 0.78
RNA-seq analysis and shRNA screen of breast cancer 0.78
High Resolution Mapping of RNA Polymerases Identifies Mechanisms of Sensitivity and Resistance to BET Inhibitors in t(8;21) AML 0.78
Transcriptome-wide identification of transient RNA G-quadruplexes in human cells 0.76
Mutant p63 disrupts the key specification switch from the multipotent cell state to stratified epithelia during epithelial differentiation/in ectodermal dysplasia disorders 0.73
miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia 0.73
Next generation sequencing of the transcriptome in MCF-7 cells with/without SRA knockdown 0.72
RNA sequencing of isogenic BRCA2 haploinsufficient vs. wild-type T-ALL cells 0.7
RNA-Sequencing of HepG2 cells treated with TGFBeta 0.7
RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 0.69
RNA-seq and small RNA-seq analysis of BORIS/CTCFL knockdown in K562 cell line 0.69
Transcriptome Analysis Reveals Distinct Responses to Physiologic versus Toxic Manganese Exposure in Human Neuroblastoma Cells 0.68
Effect of SF3B1 suppression in cancer cells with different SF3B1 copy-number levels 0.67
Effect of venetoclax, tedizolid, and combination treatment on gene expression in a venetoclax-resistant AML cell line 0.65
Muscle transcriptome analysis following Total Knee Arthroplasty with Tourniquet 0.63
Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (ChIP-seq & RNA-seq datasets) 0.61
TT-seq captures simultaneous activation of eRNAs and promoters during T cell activation 0.57
Gene expression profiles of PD1-high, PD1-intermediate, and PD1-negative tumor-infiltrating CD8 T cells in hepatocellular carcinoma 0.56
Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula 0.55
KRASG12C inhibition produces a driver-limited state revealing collateral dependencies 0.54
ChIP-seq and RNA-seq analysis of PRC2 core subunits in primary human erythroid progenitor cells 0.52
RNA-seq transcriptional profiling in primary human erythroid progenitor cells upon shRNA-mediated knockdown of PRC2 core subunits 0.52
Identification of a core p53 transcriptional program with highly fractionated tumor suppressive activity 0.48
GRO-seq from HCT116, MCF7 and SJSA cell lines treated with DMSO and Nutlin 0.48
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers (RNA-Seq) 0.47
Transcriptional Down-regulation of CCR5 in a Subset of HIV+ Controllers 0.47
RB tumor suppressor promotes cancer immunity through downregulating PD-L1 expression 0.44
Enhancer divergence and cis-regulatory evolution in the human and chimpanzee neural crest 0.35
Leucegene: ALL sequencing 0.35
LIN28A Over-expression RNAseq 0.34
Effects of plasticizers (bisphenol A, bisphenol AF) and an herbicide in MCF7 human breast cancer cells 0.34
BASP1 modifies the Tamoxifen response 0.34
Combinatorial Regulation Mediated by Biochemically Distinct Forms of SWI/SNF [RNA-Seq] 0.32
Genome-Wide Transcriptional Regulation Mediated By Biochemically Distinct Forms of SWI/SNF 0.32
RNA-sequencing of healthy human skeletal myocytes 0.32
Precise Gene Editing Preserves Hematopoietic Stem Cell Function Following Transient p53-Mediate DNA Damage Response [bulk RNA-seq] 0.31
Analyses of T-ALL (COG study) 0.28
RNA sequencing of T-ALL (COG study) 0.28
Gene Expression Profiling of Cutaneous CD30+ Lymphoproliferative Disorders by RNA-seq 0.27
Comparative Transcriptomic Analysis of Hematopoietic System Across Species by Microwell-Seq 0.26
Activity-dependent transcriptional changes in human neurons 0.25
AML subtype is a major determinant of the association between prognostic gene expression signatures and their clinical significance. 0.23
Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma 0.23
Acetylation of spliceosome protein PHF5A modulates stress responses and colorectal carcinogenesis through alternative splicing mediated upregulation of KDM3A 0.18
Targets of ROR2 overexpression in MCF-7 cells revealed a differentially regulated module of non-canonical WNT signaling pathway 0.18
Genomic expression analysis of K562 cells expressing shRNA targeting lncRNA-IIRX and control cells 0.18
Single cell transcriptomics reveals new insights on the dynamical function of transcription factors during blood stem and progenitor cell formation 0.13
Single-cell RNAseq analysis of the empty and i8TF cell lines after 3 days of BL-CFC culture 0.13
Function and hormonal regulation of GATA3 in human first trimester placentation 0.1
Migration through a small pore disrupts inactive chromatin organisation in neutrophil-like cells [RNA-seq] 0.08
RNA-seq and Hi-C sequencing of neutrophil-like cells migrated through large or small pores 0.08
RNA-seq differential expression studies: more sequence, or more replication? 0.07
Effect of Ro 08-2750 treatment on gene expression of human leukemia cell lines MOLM13 and K562 0.07
A toxicogenomics approach to screen chlorinated flame retardants tris(2-chloroethyl) phosphate and tris(2-chloroisopropyl) phosphate for potential health effects 0.06
ALS implicated protein TDP-43 sustains levels of STMN2 a mediator of motor neuron growth and repair 0.03
Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function 0.02


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